nalidixic acid and oxolinic acid

nalidixic acid has been researched along with oxolinic acid in 121 studies

Research

Studies (121)

Timeframe	Studies, this research(%)	All Research%
pre-1990	91 (75.21)	18.7374
1990's	15 (12.40)	18.2507
2000's	13 (10.74)	29.6817
2010's	2 (1.65)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Albrecht, HA; Beskid, G; Chan, KK; Christenson, JG; Cleeland, R; Deitcher, KH; Georgopapadakou, NH; Keith, DD; Pruess, DL; Sepinwall, J	1
Domagala, JM; Hanna, LD; Heifetz, CL; Hutt, MP; Mich, TF; Sanchez, JP; Solomon, M	1
Domagala, JM; Heifetz, CL; Mich, TF; Nichols, JB	1
Drake, SD; Högberg, T; Khanna, I; Mitscher, LA; Shen, LL	1
Irikura, T; Itoh, A; Koga, H; Murayama, S; Suzue, S	1
Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT	1
Aubry, A; Cambau, E; Jarlier, V; Matrat, S; Petrella, S; Sougakoff, W	1
Aarflot, L; Colquhoun, DJ; Melvold, CF	1
Aubry, A; Cambau, E; Jarlier, V; Matrat, S	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Girgis, AS; Hall, CD; Katritzky, AR; Liaqat, S; Panda, SS; Samir, A	1
Edmiston, CE; Gordon, RC; Mohan, K; Stevens, LI	1
Balogh, F; Kocsis, B; Köves, S	2
Schneck, PK; Staudenbauer, WL	1
Cozzarelli, NR; Kreuzer, KN; Peebles, CL; Sugino, A	1
Eichenwald, HF; McCracken, GH	1
Castora, FJ; Simpson, MV	1
Gilis, PM; Haemers, A; Pattyn, SR	1
Gellert, M; Itoh, T; Mizuuchi, K; O'Dea, MH; Tomizawa, JI	1
Croize, J; Le Noc, P	1
Kelenhegyi, M; Soltész, I; Szabó, Z; Varga, A	1
Little, PJ; Peddie, BA; Sincock, AR	1
Greenwood, D	1
Langsádl, L; Polívková-Konícková, L; Roubínek, F	1
Rich, GE; Steele, TW	1
Garcia Rodgriguez, JA; Gomez Garcia, AC; Saenz Gonzalez, MC	1
Sternglanz, R; Timmers, K	1
Galiński, J; Hebanowski, M; Manitius, A; Nowicki, B	1
Bobin, B; de Rautlin de la Roy, Y; Toma, V	1
Staudenbauer, WL	1
Pap, A; Szabó, I	1
Marosvári, I; Schmidt, M	1
Koch, WL; Sondack, DL	1
Acar, JF; Chabbert, YA; Duval, J; Kitzis, MD; Soussy, CJ; Thibault, M	1
Carlson, W; Dyke, JW; Gordon, RC; Stevens, LI; Thompson, TR	1
Lhotská, M; Vondrejs, V	1
Benesch, L; Graber, H; Ludwig, E; Perényi, T	1
Männistö, PT	1
Klein, D; Matsen, JM	1
Cárdenas, AM; Cortés, MP; Fernández, E; Peña, W	1
DeMarini, DM; Lawrence, BK	2
Edler, L; Popanda, O; Thielmann, HW	1
Agasøster, T; Rasmussen, KE	1
Helton, DR; Williams, PD	1
Cárdenas, AM; Cortés, MP; Fernández, E; Navarrete, E	1
Fiser-Littell, RM; Hanas, JS	1
Horikoshi, J; Kaneko, M	3
Harada, K; Ikai, Y; Kawamura, N; Nakazawa, H; Oka, H; Suzuki, M; Yamada, M	1
Duschak, VG; Goldemberg, SH	1
Brizgys, LM; Warters, RL	1
Barbanti-Brodano, G; Cermelli, C; Grossi, MP; Mannini-Palenzona, A; Paolini, L; Pietrosemoli, P; Portolani, M	1
Bia, FJ; Divo, AA; Patton, CL; Sartorelli, AC	1
Kmiec, EB; Sekiguchi, JA	1
Page, WJ; Patrick, J	1
Laporte, JM; Michel-Briand, Y; Uccelli, V	1
Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL	2
Cremer, AW; Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL; Robbins, MJ; Wall, RA; Williams, AH	1
Barba, D; Esposito, S; Galante, D; Pennucci, C	3
Albritton, WL; Cabrera-Juárez, E; Mutschler, A; Setlow, JK; Spikes, D	1
Gallagher, M; Simpson, MV; Weinberg, R	1
Angehrn, P; Dix, BA; Georgopapadakou, NH; Olson, GL; Wick, A	1
Daguet, GL; Delisle-Mizon, F; Lesage, D; Vergez, P	1
Golier, J; Langsádl, L; Menkyna, R; Silan, L	1
Amaral, L; Lorian, V; Schwarz, U	1
Smith, JT	1
Horii, S; Matsumoto, M; Yasuoka, C	1
Horie, M; Hoshino, Y; Mochizuki, E; Nakazawa, H; Nose, N; Saito, K	1
Hamamoto, K	1
Chaudhury, AM; Smith, GR	1
Grüneberg, RN	1
Capek, A; Hanová, J; Sulcová, V; Vondrejs, V	1
Vihanová, D; Vondrejs, V	1
Priel, E	1
Stevens, PJ	1
Levine, MM	1
Bebear, C; Cantet, P; Quentin, C; Renaudin, H	1
Vuye, A	1
Gadebusch, HH; Shungu, DL; Weinberg, E	1
Barry, AL; Jones, RN	2
Ayers, LW; Barry, AL; Gerlach, EH; Jones, RN; Sommers, HM; Thornsberry, C	1
Gabriel, FG; Mumtaz, G; Oriel, JD; Ridgway, GL	1
Cozzarelli, NR	1
Francke, B; Margolin, J	1
Mandelstam, J; Vazquez-Ramos, JM	1
Castora, FJ; Simpson, MV; Vissering, FF	1
Slack, R	1
Bán, E; Fehér, L; Szalka, A	1
Bonhommet, M; David, JC; Rusquet, R	1
Adeleine, P; Assenat, H; Davoine, P; François, B; Gille, Y; Schmuck, N	1
Hemmens, VJ; Moore, DE; Yip, H	1
Bán, E; Szalka, A	1
Goldstein, DJ; Nurse, KC; Wright, HT	1
Andriole, VT; Mayrer, AR	1
Bertolini, A; Castelli, M; Garuti, M; Genedani, S	1
Eda, Y; Irie, K; Izawa, A; Kisaki, Y; Komatsu, T; Nakagome, T	1
Kataoka, K; Miki, T; Mizushima, T; Ogata, Y; Sekimizu, K	1
Kondo, F; Nagata, S; Saitanu, K; Tsai, CE	1
Greenlees, KJ; Jarboe, H; Kleinow, KM; Shoemaker, KE; Toth, BR	1
Jo, K; Topal, MD	1
Miki, T; Mizushima, T; Mori, H; Ohtsuka, Y; Sekimizu, K	1
Neumann, S; Quiñones, A	1
Durán Merás, I; Galeano Díaz, T; Rodriguez Cáceres, MI; Salinas López, F	1
Chen, SN; Lee, KK; Liu, PC	1
Büyükgüzel, K	1
Jun, MJ; Kim, KM; Kim, YS; Sohn, YS; Song, R	1
Jain, A; Rajeswari, MR	1
Blanco, MM; Domínguez, L; Fernández-Garayzábal, JF; Gibello, A; Liébana, P; Moreno, MA; Porrero, MC; Vela, AI	1
Aranishi, F; Izumi, S	1
Barbato, F; Donati, E; Fanali, S; Quaglia, MG	1
Holzgrabe, U; Kiefer, W; Neugebauer, U; Popp, J; Schmitt, M; Szeghalmi, A	1
Katritzky, AR; Khelashvili, L; Kovacs, J; Munawar, MA	1
Kitano, T; Matayoshi, M; Nakamura, M; Sasaki, T	1

Reviews

5 review(s) available for nalidixic acid and oxolinic acid

Article	Year
Antimicrobial therapy in infants and children. Part I. Review of antimicrobial agents. The Journal of pediatrics, 1978, Volume: 93, Issue:3 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacitracin; Bacterial Infections; Cephalosporins; Child; Child, Preschool; Chloramphenicol; Clindamycin; Drug Combinations; Drug Therapy, Combination; Erythromycin; Humans; Infant; Kidney Diseases; Lincomycin; Nalidixic Acid; Nitrofurans; Oxolinic Acid; Penicillin Resistance; Penicillins; Polymyxins; Rifampin; Sulfamethoxazole; Sulfonamides; Tetracyclines; Trimethoprim; Vancomycin	1978
Bacillary dysentery: mechanisms and treatment. The Medical clinics of North America, 1982, Volume: 66, Issue:3 Topics: Ampicillin; Animals; Anti-Infective Agents, Urinary; Antigens, Bacterial; Bacterial Toxins; Drug Combinations; Dysentery, Bacillary; Fluid Therapy; Host-Parasite Interactions; Humans; Intestines; Lactulose; Nalidixic Acid; O Antigens; Oxolinic Acid; Polysaccharides, Bacterial; Shiga Toxins; Shigella; Sulfamethoxazole; Tetracycline; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1982
DNA gyrase and the supercoiling of DNA. Science (New York, N.Y.), 1980, Feb-29, Volume: 207, Issue:4434 Topics: Adenosine Triphosphatases; Animals; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Superhelical; Escherichia coli; Eukaryotic Cells; Genes; Macromolecular Substances; Nalidixic Acid; Novobiocin; Oxolinic Acid; Substrate Specificity; Topoisomerase II Inhibitors	1980
Review of bacterial resistance--a challenge to the treatment of urinary infection. The Journal of antimicrobial chemotherapy, 1984, Volume: 13 Suppl B Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Humans; Nalidixic Acid; Oxolinic Acid; Quinolines; Urinary Tract Infections	1984
Urinary tract antiseptics. The Medical clinics of North America, 1982, Volume: 66, Issue:1 Topics: Anti-Infective Agents, Urinary; Bacteria; Bacteriuria; Humans; Methenamine; Nalidixic Acid; Nitrofurantoin; Oxolinic Acid; Urinary Tract Infections	1982

Trials

4 trial(s) available for nalidixic acid and oxolinic acid

Article	Year
Examinations with oxolinic acid and nalidixic acid: (comparative study on the in vitro and therapeutic action). Therapia Hungarica (English edition), 1977, Volume: 25, Issue:3 Topics: Bacterial Infections; Clinical Trials as Topic; Humans; Nalidixic Acid; Oxolinic Acid; Urinary Tract Infections	1977
[Clinical experience with the use of oxolinic acid (Gramurin) and nalidixic acid (Nevigramon)]. Orvosi hetilap, 1978, Sep-10, Volume: 119, Issue:37 Topics: Anti-Infective Agents, Urinary; Clinical Trials as Topic; Drug Evaluation; Humans; Nalidixic Acid; Oxolinic Acid; Urinary Tract Infections	1978
[Letter: The effect of nalidixic acid on the mixed-fuction-oxidase system of the liver]. Orvosi hetilap, 1976, Jun-20, Volume: 117, Issue:25 Topics: Animals; Chloramphenicol; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Interactions; Humans; Liver; Nalidixic Acid; Oxolinic Acid; Rats	1976
Oxolinic acid (Prodoxol) for urinary tract infection. Drug and therapeutics bulletin, 1975, Aug-29, Volume: 13, Issue:18 Topics: Clinical Trials as Topic; Drug Evaluation; Humans; Nalidixic Acid; Oxolinic Acid; Urinary Tract Infections	1975

Other Studies

112 other study(ies) available for nalidixic acid and oxolinic acid

Article	Year
Cephalosporin 3'-quinolone esters with a dual mode of action. Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: Animals; Anti-Infective Agents; Cefotaxime; Cephalosporins; Chemical Phenomena; Chemistry; Ciprofloxacin; Enterobacter; Escherichia coli Infections; Fleroxacin; Fluoroquinolones; Hydrolysis; Mice; Molecular Structure; Pneumococcal Infections; Prodrugs; Quinolones; Rats; Staphylococcus aureus; Structure-Activity Relationship	1990
New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay. Journal of medicinal chemistry, 1986, Volume: 29, Issue:3 Topics: Anti-Bacterial Agents; Bacteria; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Microbial Sensitivity Tests; Naphthyridines; Plasmids; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors	1986
1-Ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4- dihydro-4-oxo-3-quinoline-carboxylic acid. New quinolone antibacterial with potent gram-positive activity. Journal of medicinal chemistry, 1986, Volume: 29, Issue:4 Topics: Animals; Anti-Bacterial Agents; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors	1986
Structure-activity relationships among DNA gyrase inhibitors. Synthesis and biological evaluation of 1,2-dihydro-4, 4-dimethyl-1-oxo-2-naphthalenecarboxylic acids as 1-carba bioisosteres of oxolinic acid. Journal of medicinal chemistry, 1984, Volume: 27, Issue:3 Topics: Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Naphthalenes; Oxolinic Acid; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Topoisomerase II Inhibitors	1984
Structure-activity relationships of antibacterial 6,7- and 7,8-disubstituted 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids. Journal of medicinal chemistry, 1980, Volume: 23, Issue:12 Topics: Anti-Bacterial Agents; Bacteria; Quinolines; Structure-Activity Relationship	1980
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones	2003
Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5 Topics: Anti-Infective Agents; DNA; DNA Gyrase; DNA, Superhelical; Enzyme Inhibitors; Mycobacterium leprae; Quinolones; Topoisomerase II Inhibitors	2007
gyrA and parC Mutations and associated quinolone resistance in Vibrio anguillarum serotype O2b strains isolated from farmed Atlantic cod (Gadus morhua) in Norway. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Animals; Base Sequence; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fish Diseases; Fisheries; Gadus morhua; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Norway; Quinolones; Serotyping; Vibrio; Vibrio Infections	2007
Are all the DNA gyrase mutations found in Mycobacterium leprae clinical strains involved in resistance to fluoroquinolones? Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2 Topics: Anti-Infective Agents; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium leprae	2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Novel antibacterial active quinolone-fluoroquinolone conjugates and 2D-QSAR studies. Bioorganic & medicinal chemistry letters, 2015, Sep-15, Volume: 25, Issue:18 Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Quinolones	2015
Comparative in vitro studies of cinoxacin, nalidixic acid, and oxolinic acid. Antimicrobial agents and chemotherapy, 1976, Volume: 10, Issue:6 Topics: Culture Media; Dioxolanes; Drug Resistance, Microbial; Hydrogen-Ion Concentration; Nalidixic Acid; Oxolinic Acid; Protein Binding; Pyridazines; Shigella flexneri; Shigella sonnei	1976
Oxolinic acid, nalidixic acid and 5Nok in the treatment of urinary tract infections. Therapia Hungarica (English edition), 1978, Volume: 26, Issue:1 Topics: Drug Evaluation; Humans; Hydroxyquinolines; Nalidixic Acid; Oxolinic Acid; Oxyquinoline; Urinary Tract Infections	1978
Escherichia coli DNA synthesis in vitro: insensitivity of ATP-dependent DNA repair to inhibition by novobiocin. Nucleic acids research, 1977, Volume: 4, Issue:6 Topics: Adenosine Triphosphate; DNA; DNA Repair; Escherichia coli; Guanosine Monophosphate; Kinetics; Nalidixic Acid; Novobiocin; Oxolinic Acid; Ultraviolet Rays	1977
Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:11 Topics: Bacterial Proteins; Coliphages; DNA Replication; DNA Topoisomerases, Type I; DNA, Superhelical; Enzyme Inhibitors; Escherichia coli; Molecular Weight; Nalidixic Acid; Oxolinic Acid; Protein Biosynthesis; Transduction, Genetic	1977
Search for a DNA gyrase in mammalian mitochondria. The Journal of biological chemistry, 1979, Nov-25, Volume: 254, Issue:22 Topics: Animals; Anti-Bacterial Agents; Coumarins; DNA Topoisomerases, Type II; DNA, Mitochondrial; Kinetics; Mitochondria, Liver; Nalidixic Acid; Novobiocin; Oxolinic Acid; Pyrroles; Rats	1979
Comparative in vitro studies of nalidixic acid, oxolinic acid, and a new analog with thieno (2,3-b) pyridine structure. Antimicrobial agents and chemotherapy, 1978, Volume: 13, Issue:3 Topics: Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry; Microbial Sensitivity Tests; Nalidixic Acid; Nicotinic Acids; Oxolinic Acid	1978
Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity. Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:11 Topics: DNA, Bacterial; DNA, Superhelical; Drug Resistance, Microbial; Escherichia coli; Nalidixic Acid; Oxolinic Acid	1977
[Present frequency of the different Serratia species isolated in Grenoble University Hospital Center (author's transl)]. Pathologie-biologie, 1977, Volume: 25, Issue:9 Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Cross Infection; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Nicotinic Acids; Oxolinic Acid; Piperazines; Serratia; Urine	1977
Urinary tract infection in general practice. The New Zealand medical journal, 1978, Oct-25, Volume: 88, Issue:622 Topics: Adolescent; Amoxicillin; Ampicillin; Escherichia coli; Family Practice; Female; Follow-Up Studies; Gram-Negative Anaerobic Bacteria; Humans; Klebsiella; Leukocyte Count; Male; Nalidixic Acid; Oxolinic Acid; Pregnancy; Proteus; Urinary Tract Infections	1978
Activity of flumequine against Escherichia coli: in vitro comparison with nalidixic and oxolinic acids. Antimicrobial agents and chemotherapy, 1978, Volume: 13, Issue:3 Topics: Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Oxolinic Acid; Quinolizines	1978
[A comparison of the effects of three urinary infection chemotherapeutics - nalidixic, oxolinic, and pipemidic acids (author's transl)]. Casopis lekaru ceskych, 1979, May-11, Volume: 118, Issue:19 Topics: Animals; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Microbial Sensitivity Tests; Nalidixic Acid; Nicotinic Acids; Oxolinic Acid; Pipemidic Acid; Rats; Urinary Tract Infections	1979
The rational use of antibiotics in general practice. Australian family physician, 1977, Volume: 6, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Clindamycin; Drug Combinations; Epididymitis; Epiglottis; Erythromycin; Family Practice; Female; Humans; Intestinal Diseases; Laryngitis; Male; Mouth Diseases; Nalidixic Acid; Nitrofurantoin; Otitis Media; Oxolinic Acid; Penicillins; Pharyngitis; Respiratory Tract Infections; Skin Diseases, Infectious; Sulfamethoxazole; Tetracyclines; Trimethoprim; Urethritis; Urinary Tract Infections	1977
In vitro susceptibility studies with piromidic acid. The Journal of antimicrobial chemotherapy, 1978, Volume: 4, Issue:3 Topics: Anti-Bacterial Agents; Dioxolanes; Enterobacteriaceae; Microbial Sensitivity Tests; Nalidixic Acid; Nicotinic Acids; Oxolinic Acid; Staphylococcus aureus	1978
Ionization and divalent cation dissociation constants of nalidixic and oxolinic acids. Bioinorganic chemistry, 1978, Volume: 9, Issue:2 Topics: Cations, Divalent; Chemical Phenomena; Chemistry; Nalidixic Acid; Oxolinic Acid; Potentiometry; Spectrophotometry, Ultraviolet	1978
[Comparison of antibacterial activity of oxolinic acid (Gramurin) and nalidixic acid (Nevigramon) in vitro and in patients with urinary tract infections]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1978, Aug-21, Volume: 33, Issue:34 Topics: Adult; Aged; Bacteria; Female; Humans; Male; Middle Aged; Nalidixic Acid; Oxolinic Acid; Urinary Tract Infections	1978
In vitro activity of oxolinic acid and nalidixic acid against common urinary pathogens: a comparative study. Current medical research and opinion, 1978, Volume: 5, Issue:9 Topics: Bacteria; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Oxolinic Acid; Urinary Tract Infections	1978
Replication of Escherichia coli DNA in vitro: inhibition by oxolinic acid. European journal of biochemistry, 1976, Mar-01, Volume: 62, Issue:3 Topics: Adenosine Triphosphate; DNA Replication; Escherichia coli; Kinetics; Nalidixic Acid; Oxolinic Acid; Structure-Activity Relationship; Transcription, Genetic	1976
[Oxolinic acid therapy of urinary tract infections in infancy]. Acta paediatrica Academiae Scientiarum Hungaricae, 1976, Volume: 17, Issue:4 Topics: Anti-Infective Agents, Urinary; Child, Preschool; Drug Resistance, Microbial; Escherichia coli Infections; Female; Humans; Infant; Klebsiella Infections; Male; Nalidixic Acid; Oxolinic Acid; Proteus Infections; Urinary Tract Infections	1976
Analysis of urinary tract antibacterial agents in pharmaceutical dosage form by high-performance liquid chromatography. Journal of chromatography, 1977, Feb-11, Volume: 132, Issue:2 Topics: Anti-Infective Agents, Urinary; Chromatography, High Pressure Liquid; Dioxolanes; Dosage Forms; Nalidixic Acid; Oxolinic Acid; Pyridazines	1977
[Comparative study of six quinolone antibacterials (author's transl)]. Annales de microbiologie, 1977, Volume: 128B, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; Dioxolanes; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; Nalidixic Acid; Nicotinic Acids; Oxolinic Acid; Pyridazines; Pyrrolidines; Quinolizines; Species Specificity	1977
Antimicrobial resistance of Shigellae isolated in Michigan. JAMA, 1975, Mar-17, Volume: 231, Issue:11 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Dysentery, Bacillary; Humans; Michigan; Nalidixic Acid; Oxolinic Acid; Rural Population; Shigella; Shigella boydii; Shigella dysenteriae; Shigella flexneri; Shigella sonnei; Sulfamethoxazole; Tetracycline; Trimethoprim; Urban Population	1975
DNA synthesis - dependent cell division of Escherichia coli 15 TAU after arginine and uracil starvation. Folia microbiologica, 1975, Volume: 20, Issue:1 Topics: Arginine; Cell Count; Cell Division; Colorimetry; DNA Replication; DNA, Bacterial; Escherichia coli; Mutation; Nalidixic Acid; Oxolinic Acid; Thymine; Time Factors; Uracil	1975
[Studies on the interaction of nalidixic acid and oxolinic acid]. Orvosi hetilap, 1975, Dec-14, Volume: 116, Issue:50 Topics: Drug Interactions; Drug Therapy, Combination; Humans; Liver; Nalidixic Acid; Oxolinic Acid; Urinary Tract Infections	1975
Pharmacokinetics of nalidixinic acid and oxolinic acid in healthy women. Clinical pharmacology and therapeutics, 1976, Volume: 19, Issue:1 Topics: Administration, Oral; Adult; Biological Assay; Drug Administration Schedule; Drug Storage; Eating; Female; Humans; Kinetics; Middle Aged; Nalidixic Acid; Oxolinic Acid; Time Factors	1976
In vitro susceptibility comparisons and recommendations for oxolinic acid. Antimicrobial agents and chemotherapy, 1976, Volume: 9, Issue:4 Topics: Bacteria; Enterobacteriaceae; Microbial Sensitivity Tests; Nalidixic Acid; Oxolinic Acid; Spectrophotometry, Ultraviolet; Staphylococcus	1976
Lipid peroxidation and loss of potassium from red blood cells produced by phototoxic quinolones. Toxicology, 1992, Volume: 72, Issue:2 Topics: 4-Quinolones; Anti-Infective Agents; Cell Membrane Permeability; Cholesterol; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Lipid Peroxidation; Nalidixic Acid; Oxidation-Reduction; Oxolinic Acid; Photolysis; Potassium; Quinolones	1992
Prophage induction by DNA topoisomerase II poisons and reactive-oxygen species: role of DNA breaks. Mutation research, 1992, Volume: 267, Issue:1 Topics: Amsacrine; Azides; Bacteriophage lambda; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Ellipticines; Escherichia coli; Free Radicals; Hydrogen Peroxide; Lysogeny; Nalidixic Acid; Novobiocin; Oxolinic Acid; Oxygen; Paraquat; Sodium Azide; SOS Response, Genetics; Teniposide; Topoisomerase II Inhibitors; Virus Replication	1992
The effects of inhibitors of topoisomerase II and quinacrine on ultraviolet-light-induced DNA incision in normal and xeroderma pigmentosum fibroblasts. Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:1 Topics: Aminocoumarins; Cell Cycle; Cells, Cultured; Coumarins; DNA; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Fibroblasts; Genetic Variation; Humans; Nalidixic Acid; Novobiocin; Oxolinic Acid; Quinacrine; Topoisomerase II Inhibitors; Ultraviolet Rays; Xeroderma Pigmentosum	1991
Automated analysis of oxolinic acid and flumequine in salmon whole blood and plasma using dialysis combined with trace enrichment as on-line sample preparation for high-performance liquid chromatography. Journal of chromatography, 1991, Mar-08, Volume: 564, Issue:1 Topics: Animals; Autoanalysis; Chromatography, High Pressure Liquid; Dialysis; Fluoroquinolones; Nalidixic Acid; Oxolinic Acid; Quinolizines; Salmon	1991
The proconvulsive activity of quinolone antibiotics in an animal model. Toxicology letters, 1991, Volume: 58, Issue:1 Topics: Animals; Anti-Infective Agents; Convulsants; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Nalidixic Acid; Oxolinic Acid; Pentylenetetrazole; Picrotoxin; Seizures; Strychnine	1991
Phototoxicity induced by nalidixic and oxolinic acids: decrease in cell survival of chick embryo fibroblasts and Hep-2 cells. Journal of photochemistry and photobiology. B, Biology, 1991, Volume: 9, Issue:2 Topics: Animals; Carcinoma; Cell Line; Cell Survival; Chick Embryo; Fibroblasts; Humans; Laryngeal Neoplasms; Light; Nalidixic Acid; Oxolinic Acid; Tumor Cells, Cultured	1991
Novobiocin inhibits Xenopus transcription factor IIIA-DNA interactions. The Journal of biological chemistry, 1987, Sep-05, Volume: 262, Issue:25 Topics: Aminocoumarins; Animals; Coumarins; Deoxyribonuclease I; DNA; Escherichia coli; Nalidixic Acid; Novobiocin; Nucleic Acid Renaturation; Oxolinic Acid; RNA; Topoisomerase II Inhibitors; Transcription Factor TFIIIA; Transcription Factors; Xenopus laevis	1987
Reversible suppression by nalidixic acid of anchorage-independent growth of mouse cells transformed by 3-methylcholanthrene or an activated c-Ha-ras gene. British journal of cancer, 1989, Volume: 60, Issue:6 Topics: Animals; Cell Line, Transformed; Clone Cells; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mitosis; Nalidixic Acid; Oncogene Protein p21(ras); Oncogenes; Oxolinic Acid; Pipemidic Acid	1989
Improvement of chemical analysis of antibiotics. XVI. Simple and rapid determination of residual pyridonecarboxylic acid antibacterials in fish using a prepacked amino cartridge. Journal of chromatography, 1989, Aug-30, Volume: 477, Issue:2 Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Drug Residues; Fishes; Food Analysis; Nalidixic Acid; Oxolinic Acid; Piromidic Acid	1989
Effects of DNA gyrase inhibitors in a polyamine-auxotrophic strain of Escherichia coli. Biochimica et biophysica acta, 1987, Oct-09, Volume: 910, Issue:1 Topics: DNA, Bacterial; Escherichia coli; Heat-Shock Proteins; Nalidixic Acid; Novobiocin; Oxolinic Acid; Polyamines; Putrescine; Topoisomerase II Inhibitors	1987
Topoisomerase inhibitors suppressed lithocholic acid-induced promotion of transformation in BALB/3T3. British journal of cancer, 1987, Volume: 56, Issue:5 Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Fibroblasts; Lithocholic Acid; Methylcholanthrene; Mice; Nalidixic Acid; Oxolinic Acid; Topoisomerase I Inhibitors	1987
Effect of topoisomerase II inhibitors on hyperthermic cytotoxicity. Cancer research, 1988, Jul-15, Volume: 48, Issue:14 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Female; HeLa Cells; Hot Temperature; Humans; Nalidixic Acid; Novobiocin; Nucleoproteins; Ovary; Oxolinic Acid; Topoisomerase II Inhibitors	1988
Suppression of BK virus replication and cytopathic effect by inhibitors of prokaryotic DNA gyrase. Antiviral research, 1988, Volume: 9, Issue:3 Topics: Antigens, Viral; BK Virus; Cytopathogenic Effect, Viral; DNA, Viral; Nalidixic Acid; Oxolinic Acid; Polyomavirus; Topoisomerase II Inhibitors; Virus Replication	1988
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8 Topics: Aminocoumarins; Animals; Anti-Infective Agents; Chloroquine; Ciprofloxacin; Coumarins; Drug Interactions; Drug Resistance; Enoxacin; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Oxolinic Acid; Pefloxacin; Plasmodium falciparum; Tetracycline; Topoisomerase II Inhibitors	1988
Studies on DNA topoisomerase activity during in vitro chromatin assembly. Molecular and cellular biochemistry, 1988, Volume: 83, Issue:2 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Chromatin; Diminazene; DNA Topoisomerases, Type I; DNA, Superhelical; In Vitro Techniques; Nalidixic Acid; Nucleosomes; Oxolinic Acid; Plasmids; Xenopus laevis	1988
The DNA gyrase inhibitors, nalidixic acid and oxolinic acid, prevent iron-mediated repression of catechol siderophore synthesis in Azotobacter vinelandii. Biology of metals, 1988, Volume: 1, Issue:1 Topics: Azotobacter; Catechols; Iron; Iron Chelating Agents; Nalidixic Acid; Oxolinic Acid; Peptide Biosynthesis; Peptides; Siderophores; Time Factors; Topoisomerase II Inhibitors	1988
Mutagenicity of topoisomerase-active agents in bacteriophage T4. Teratogenesis, carcinogenesis, and mutagenesis, 1988, Volume: 8, Issue:5 Topics: Amsacrine; Dactinomycin; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Ellipticines; Mutation; Nalidixic Acid; Novobiocin; Oxolinic Acid; T-Phages	1988
[Inhibition of the maintenance and transfer of antibiotic-resistance plasmids by quinolones]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1985, Volume: 179, Issue:5 Topics: Anti-Bacterial Agents; Conjugation, Genetic; Escherichia coli; Fluoroquinolones; Nalidixic Acid; Oxolinic Acid; Quinolines; Quinolizines; R Factors; Structure-Activity Relationship	1985
The comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens. Drugs under experimental and clinical research, 1985, Volume: 11, Issue:4 Topics: 4-Quinolones; Aeromonas; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter fetus; Cinoxacin; Ciprofloxacin; Diarrhea; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Intestines; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Salmonella; Shigella; Vibrio cholerae; Vibrio parahaemolyticus; Yersinia enterocolitica	1985
The comparative activity of twelve 4-quinolone antimicrobials against Haemophilus influenzae and Streptococcus pneumoniae. Drugs under experimental and clinical research, 1985, Volume: 11, Issue:4 Topics: 4-Quinolones; Anti-Infective Agents; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Streptococcus pneumoniae	1985
Comparative in vitro studies with 4-quinolone antimicrobials. Drugs under experimental and clinical research, 1985, Volume: 11, Issue:5 Topics: 4-Quinolones; Anti-Infective Agents; Bacteria; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones	1985
Comparative in vitro activity of ciprofloxacin and five other quinoline derivatives against gram-negative isolates. Drugs under experimental and clinical research, 1985, Volume: 11, Issue:5 Topics: Bacteriuria; Cinoxacin; Ciprofloxacin; Gram-Negative Bacteria; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Pipemidic Acid; Quinolines	1985
Mutations affecting gyrase in Haemophilus influenzae. Journal of bacteriology, 1985, Volume: 164, Issue:2 Topics: Aminocoumarins; Coumarins; DNA Repair; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Genes, Regulator; Genetic Complementation Test; Genetic Linkage; Haemophilus influenzae; Mutation; Nalidixic Acid; Novobiocin; Oxolinic Acid; Phenotype; Promoter Regions, Genetic; R Factors; Recombination, Genetic; Rifampin; Ultraviolet Rays	1985
Effect of the bacterial DNA gyrase inhibitors, novobiocin, nalidixic acid, and oxolinic acid, on oxidative phosphorylation. The Journal of biological chemistry, 1986, Jul-05, Volume: 261, Issue:19 Topics: Animals; Escherichia coli; Glutamine; Kinetics; Mitochondria, Liver; Nalidixic Acid; Novobiocin; Oxidative Phosphorylation; Oxolinic Acid; Rats; Topoisomerase II Inhibitors	1986
Monocyclic and tricyclic analogs of quinolones: mechanism of action. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:4 Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; DNA Replication; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Klebsiella pneumoniae; Nalidixic Acid; Nicotinic Acids; Oxolinic Acid; Quinolines; Quinolones; Staphylococcus aureus; Structure-Activity Relationship	1987
Cross resistance of quinolone derivatives in gram-negative bacteria. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1985, Volume: 4, Issue:2 Topics: Ciprofloxacin; Drug Resistance, Microbial; Gram-Negative Bacteria; Humans; Mutation; Nalidixic Acid; Nicotinic Acids; Oxolinic Acid; Pipemidic Acid; Quinolines	1985
Occurrence of gram negative bacteria in midstream bladder urine and their sensitivity to quinoline derivatives. Microbiologica, 1985, Volume: 8, Issue:3 Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Drug Resistance, Microbial; Female; Gram-Negative Bacteria; Humans; Male; Middle Aged; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Pipemidic Acid; Quinolines; Species Specificity; Urinary Tract Infections; Urine	1985
[Comparison of the in vitro activity of 6 quinolones on Pseudomonas sp]. Pathologie-biologie, 1985, Volume: 33, Issue:5 Topics: Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Pseudomonas; Pseudomonas aeruginosa; Quinolines	1985
Nalidixic acid and oxolinic acid reversibly suppress 3-methylcholanthrene-induced cell transformation of BALB/3T3 mouse cells. International journal of cancer, 1988, Dec-15, Volume: 42, Issue:6 Topics: Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Methylcholanthrene; Mice; Nalidixic Acid; Oxolinic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic	1988
[Comparison of the antibacterial effects of ofloxacin, oxolinic acid and nalidixic acid]. Ceskoslovenska epidemiologie, mikrobiologie, imunologie, 1988, Volume: 37, Issue:5 Topics: Anti-Bacterial Agents; Bacteriuria; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Oxolinic Acid; Pseudomonas	1988
Penicillin-binding proteins of filaments of Escherichia coli induced by low concentrations of nalidixic acid, oxolinic acid, novobiocin or nitrofurantoin. Drugs under experimental and clinical research, 1986, Volume: 12, Issue:8 Topics: Acyltransferases; Anti-Infective Agents, Urinary; Bacterial Proteins; Carrier Proteins; Escherichia coli; Hexosyltransferases; Multienzyme Complexes; Muramoylpentapeptide Carboxypeptidase; Nalidixic Acid; Nitrofurantoin; Novobiocin; Oxolinic Acid; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases	1986
Frequency and expression of mutational resistance to the 4-quinolone antibacterials. Scandinavian journal of infectious diseases. Supplementum, 1986, Volume: 49 Topics: 4-Quinolones; Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fluoroquinolones; Mutation; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pipemidic Acid; Quinolines; Quinolizines; Quinolones	1986
High-performance liquid chromatographic method for the simultaneous determination of oxolinic, nalidixic and piromidic acids in cultured fish. Journal of chromatography, 1987, Feb-13, Volume: 388, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Culture Techniques; Fishes; Nalidixic Acid; Nicotinic Acids; Oxolinic Acid; Piromidic Acid; Spectrophotometry, Ultraviolet	1987
Simultaneous determination of nalidixic acid, oxolinic acid and piromidic acid in fish by high-performance liquid chromatography with fluorescence and UV detection. Journal of chromatography, 1987, Jul-31, Volume: 402 Topics: Animals; Carps; Chromatography, High Pressure Liquid; Fishes; Indicators and Reagents; Mass Spectrometry; Nalidixic Acid; Nicotinic Acids; Oxolinic Acid; Piromidic Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Trout	1987
Rapid high-performance liquid chromatographic method for the determination of oxolinic acid in chicken plasma. Journal of chromatography, 1986, Sep-05, Volume: 381, Issue:2 Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Kinetics; Nalidixic Acid; Oxolinic Acid; Spectrophotometry, Ultraviolet	1986
Role of Escherichia coli RecBC enzyme in SOS induction. Molecular & general genetics : MGG, 1985, Volume: 201, Issue:3 Topics: DNA Repair; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Escherichia coli Proteins; Exodeoxyribonuclease V; Exodeoxyribonucleases; Gene Expression Regulation; Genes, Bacterial; Nalidixic Acid; Oxolinic Acid	1985
Letter: Oxolinic acid in urinary infections. Lancet (London, England), 1974, Nov-02, Volume: 2, Issue:7888 Topics: Drug Evaluation; Drug Resistance, Microbial; Enterobacteriaceae; Humans; Nalidixic Acid; Oxolinic Acid; Pseudomonas; Staphylococcus; Urinary Tract Infections	1974
Effect of derivatives of 3-quinolinecarboxylic acid on DNA synthesis, growth and division in Escherichia coli 15 TAU. Folia microbiologica, 1974, Volume: 19, Issue:4 Topics: Carboxylic Acids; Cell Count; Cell Division; Chemical Phenomena; Chemistry; DNA Replication; DNA, Bacterial; Escherichia coli; Nalidixic Acid; Oxolinic Acid; Quinolines; Thymine; Tritium	1974
Induction of bacteriophage lambda with oxolinic and nalidixic acid. Folia microbiologica, 1974, Volume: 19, Issue:5 Topics: Coliphages; Culture Media; Escherichia coli; Lysogeny; Nalidixic Acid; Oxolinic Acid; Time Factors; Virus Replication	1974
Inhibition of postreplication recombinational repair by DNA-gyrase antagonists in Escherichia coli. Cell biology international reports, 1984, Volume: 8, Issue:9 Topics: Aminocoumarins; Bacterial Proteins; Coumarins; DNA Repair; DNA, Bacterial; Escherichia coli; Nalidixic Acid; Oxolinic Acid; Recombination, Genetic; Topoisomerase II Inhibitors	1984
Bactericidal effect against Escherichia coli of nalidixic acid and four structurally related compounds. The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol; DNA, Bacterial; Escherichia coli; Nalidixic Acid; Oxolinic Acid; Rifampin; RNA, Bacterial	1980
[Comparative in vitro effect of 7 quinolones on Ureaplasma urealyticum]. Pathologie-biologie, 1983, Volume: 31, Issue:6 Topics: 4-Quinolones; Anti-Bacterial Agents; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Ureaplasma	1983
In vitro comparison of norfloxacin with nalidixic acid, cinoxacin and oxolinic acid. Arzneimittel-Forschung, 1983, Volume: 33, Issue:12 Topics: Anti-Bacterial Agents; Cinoxacin; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Oxolinic Acid	1983
Effectiveness of the antimicrobial removal device, BACTEC 16B medium, and thiol broth in neutralizing antibacterial activities of imipenem, norfloxacin, and related agents. Journal of clinical microbiology, 1984, Volume: 19, Issue:2 Topics: Anti-Bacterial Agents; Bacteria; Bacteriological Techniques; Blood; Cefoxitin; Ceftazidime; Cephalosporins; Culture Media; Evaluation Studies as Topic; Humans; Imipenem; Moxalactam; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Sulfhydryl Compounds; Thienamycins; Urine	1984
Norfloxacin (MK-0366, AM-715): in vitro activity and cross-resistance with other organic acids including quality control limits for disk diffusion testing. Diagnostic microbiology and infectious disease, 1983, Volume: 1, Issue:2 Topics: Acinetobacter; Anti-Infective Agents, Urinary; Bacteria; Cinoxacin; Drug Combinations; Drug Resistance, Microbial; Enterobacteriaceae; Enterococcus faecalis; Escherichia coli; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Pseudomonas; Pseudomonas aeruginosa; Quality Control; Reference Standards; Staphylococcus aureus; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1983
Antibacterial activities of ciprofloxacin, norfloxacin, oxolinic acid, cinoxacin, and nalidixic acid. Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:5 Topics: Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Micrococcaceae; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Quinolines	1984
Cross-resistance among cinoxacin, ciprofloxacin, DJ-6783, enoxacin, nalidixic acid, norfloxacin, and oxolinic acid after in vitro selection of resistant populations. Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:6 Topics: Anti-Bacterial Agents; Bacteria; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Nalidixic Acid; Naphthyridines; Norfloxacin; Oxolinic Acid; Pseudomonas aeruginosa; Quinolines	1984
The activity of ciprofloxacin and other 4-quinolones against Chlamydia trachomatis and Mycoplasmas in vitro. European journal of clinical microbiology, 1984, Volume: 3, Issue:4 Topics: 4-Quinolones; Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Mycoplasma; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Oxytetracycline; Quinolines; Quinolones; Ureaplasma	1984
Effect of novobiocin and other DNA gyrase inhibitors on virus replication and DNA synthesis in herpes simplex virus type 1-infected BHK cells. The Journal of general virology, 1981, Volume: 52, Issue:Pt 2 Topics: Aminocoumarins; Animals; Cell Division; Cell Line; Coumarins; Cricetinae; DNA; DNA, Viral; Nalidixic Acid; Novobiocin; Oxolinic Acid; Pyrroles; Simplexvirus; Topoisomerase II Inhibitors; Virus Replication	1981
Oxolinic acid-resistant mutants of Bacillus subtilis. Journal of general microbiology, 1981, Volume: 127, Issue:1 Topics: Bacillus subtilis; Cell Membrane Permeability; Chromosome Mapping; Chromosomes, Bacterial; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Mutation; Nalidixic Acid; Oxolinic Acid; Time Factors; Topoisomerase II Inhibitors	1981
The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria. Biochimica et biophysica acta, 1983, Sep-09, Volume: 740, Issue:4 Topics: Aminocoumarins; Animals; Anti-Bacterial Agents; Coumarins; DNA Replication; DNA, Mitochondrial; DNA, Superhelical; Escherichia coli; Mitochondria, Liver; Molecular Weight; Nalidixic Acid; Novobiocin; Oxolinic Acid; Rats; Topoisomerase II Inhibitors	1983
Gramurin (oxolinic acid) treatment in acute enterocolitis accompanied by the discharge of bloody stool. Therapia Hungarica (English edition), 1983, Volume: 31, Issue:2 Topics: Acute Disease; Enterocolitis; Humans; Male; Melena; Middle Aged; Nalidixic Acid; Oxolinic Acid	1983
Quinolone antibiotics inhibit eucaryotic DNA polymerase alpha and beta, terminal deoxynucleotidyl transferase but not DNA ligase. Biochemical and biophysical research communications, 1984, Jun-29, Volume: 121, Issue:3 Topics: Animals; Anti-Infective Agents, Urinary; Chickens; DNA Ligases; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; DNA Polymerase I; DNA Polymerase II; Electrophoresis, Polyacrylamide Gel; Kinetics; Nalidixic Acid; Nucleic Acid Synthesis Inhibitors; Oxolinic Acid; Pefloxacin; Polynucleotide Ligases; Quinolines; Thymus Gland	1984
[Variations in vitro of the efficacy of quinolones as a function of pH]. Nephrologie, 1983, Volume: 4, Issue:6 Topics: Anti-Infective Agents, Urinary; Bacteria; Humans; Hydrogen-Ion Concentration; Nalidixic Acid; Oxolinic Acid; Pipemidic Acid; Quinolines	1983
Photosensitization drugs: nalidixic and oxolinic acids. Photochemistry and photobiology, 1984, Volume: 39, Issue:1 Topics: Humans; Nalidixic Acid; Oxolinic Acid; Photosensitivity Disorders; Structure-Activity Relationship; Ultraviolet Rays	1984
Microbiological and clinical examinations supporting the effectivity of oxolinic acid (Gramurin) in the treatment of acute enterocolitis. Therapia Hungarica (English edition), 1982, Volume: 30, Issue:1 Topics: Adult; Child; Enterocolitis; Humans; Male; Microbial Sensitivity Tests; Nalidixic Acid; Oxolinic Acid	1982
Nalidixic acid, oxolinic acid, and novobiocin inhibit yeast glycyl- and leucyl-transfer RNA synthetases. Science (New York, N.Y.), 1981, Jul-24, Volume: 213, Issue:4506 Topics: Amino Acyl-tRNA Synthetases; Glycine-tRNA Ligase; Kinetics; Leucine-tRNA Ligase; Nalidixic Acid; Novobiocin; Oxolinic Acid; Saccharomyces cerevisiae	1981
Trimethoprim enhances the antibacterial activity of nalidixic and oxolinic acids and delays the emergence of resistance. Experientia, 1980, Feb-15, Volume: 36, Issue:2 Topics: Bacteria; Drug Resistance, Microbial; Drug Synergism; Nalidixic Acid; Oxolinic Acid; Species Specificity; Trimethoprim	1980
Antibacterial activity of miloxacin. Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:1 Topics: 4-Quinolones; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Enterobacteriaceae; Mice; Microbial Sensitivity Tests; Nalidixic Acid; Oxolinic Acid	1980
Identification of DNA topoisomerases involved in immediate and transient DNA relaxation induced by heat shock in Escherichia coli. Molecular & general genetics : MGG, 1994, Sep-01, Volume: 244, Issue:5 Topics: DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Electrophoresis, Agar Gel; Escherichia coli; Heat-Shock Proteins; Nalidixic Acid; Nucleic Acid Conformation; Oxolinic Acid; Plasmids; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	1994
Determination of pyridonecarboxylic acids in plasma by reverse-phase high-performance liquid chromatography. Microbios, 1994, Volume: 77, Issue:312 Topics: Animals; Anti-Infective Agents, Urinary; Biological Assay; Carboxylic Acids; Chickens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Residues; Escherichia coli; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Oxolinic Acid; Pipemidic Acid; Sensitivity and Specificity; Spectrophotometry, Ultraviolet	1994
Pharmacokinetics, bioavailability, plasma protein binding and disposition of nalidixic acid in rainbow trout (Oncorhynchus mykiss). Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:9 Topics: Administration, Oral; Animals; Biological Availability; Blood Proteins; Chromatography, High Pressure Liquid; Injections, Intravenous; Nalidixic Acid; Oncorhynchus mykiss; Oxolinic Acid; Protein Binding; Tissue Distribution	1993
Changing a leucine to a lysine residue makes NaeI endonuclease hypersensitive to DNA intercalative drugs. Biochemistry, 1996, Aug-06, Volume: 35, Issue:31 Topics: Amsacrine; Antineoplastic Agents; Binding Sites; Daunorubicin; Deoxyribonuclease EcoRI; Deoxyribonucleases, Type II Site-Specific; DNA Nucleotidyltransferases; DNA Topoisomerases, Type I; Ellipticines; Enzyme Inhibitors; Integrases; Intercalating Agents; Kinetics; Lysine; Nalidixic Acid; Novobiocin; Oxolinic Acid; Point Mutation; Recombinant Proteins; Recombinases; Topoisomerase I Inhibitors	1996
Increase in synthesis and stability of sigma 32 on treatment with inhibitors of DNA gyrase in Escherichia coli. Molecular & general genetics : MGG, 1996, Dec-13, Volume: 253, Issue:3 Topics: Anti-Infective Agents; Bacterial Proteins; DNA Topoisomerases, Type II; Enzyme Inhibitors; Escherichia coli; Heat-Shock Proteins; Mutation; Nalidixic Acid; Novobiocin; Oxolinic Acid; Sigma Factor; Topoisomerase II Inhibitors; Transcription Factors	1996
Discoordinate gene expression of gyrA and gyrB in response to DNA gyrase inhibition in Escherichia coli. Journal of basic microbiology, 1997, Volume: 37, Issue:1 Topics: Aminocoumarins; beta-Galactosidase; Blotting, Southern; Cloning, Molecular; Coumarins; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Electrophoresis, Agar Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Reporter; Lac Operon; Nalidixic Acid; Novobiocin; Oxolinic Acid; Plasmids; Protein Biosynthesis; Quinolones; Topoisomerase II Inhibitors	1997
Determination of the chemotherapeutic quinolonic and cinolonic derivatives in urine by high-performance liquid chromatography with ultraviolet and fluorescence detection in series. Journal of chromatography. A, 1997, Nov-07, Volume: 787, Issue:1-2 Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Cinoxacin; Humans; Nalidixic Acid; Oxolinic Acid; Pipemidic Acid; Piromidic Acid; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet	1997
Susceptibility of different isolates of Vibrio harveyi to antibiotics. Microbios, 1997, Volume: 91, Issue:368-369 Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Ciprofloxacin; Decapoda; Doxycycline; Drug Resistance, Microbial; Erythromycin; Fish Diseases; Fishes; Microbial Sensitivity Tests; Nalidixic Acid; Nitrofurantoin; Novobiocin; Oxolinic Acid; Oxytetracycline; Penicillins; Seawater; Streptomycin; Sulfonamides; Vancomycin; Vibrio; Vibrio Infections; Water Microbiology	1997
Positive effects of some gyrase inhibitors on survival and development of Pimpla turionellae (Hymenoptera: Ichneumonidae) larvae reared on an artificial diet. Journal of economic entomology, 2001, Volume: 94, Issue:1 Topics: Animals; Enzyme Inhibitors; Larva; Nalidixic Acid; Novobiocin; Oxolinic Acid; Topoisomerase II Inhibitors; Wasps	2001
Synthesis, characterization and antitumor activity of quinolone-platinum(II) conjugates. Journal of inorganic biochemistry, 2001, Dec-01, Volume: 87, Issue:3 Topics: Animals; Antineoplastic Agents; Carboplatin; Fluoroquinolones; Leukemia L1210; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Nalidixic Acid; Oxolinic Acid; Platinum; Quinolizines; Quinolones; Spectrophotometry, Infrared; Tumor Cells, Cultured	2001
Preferential binding of quinolones to DNA with alternating G, C / A, T sequences: a spectroscopic study. Journal of biomolecular structure & dynamics, 2002, Volume: 20, Issue:2 Topics: Base Pairing; Base Sequence; Circular Dichroism; DNA, Bacterial; Escherichia coli; Molecular Structure; Nalidixic Acid; Nucleic Acid Conformation; Oxolinic Acid; Polynucleotides; Quinolones; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship	2002
Analysis of the gyrA gene of clinical Yersinia ruckeri isolates with reduced susceptibility to quinolones. Applied and environmental microbiology, 2004, Volume: 70, Issue:1 Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Infective Agents; DNA Gyrase; Drug Resistance, Bacterial; Fish Diseases; Microbial Sensitivity Tests; Molecular Sequence Data; Nalidixic Acid; Oncorhynchus mykiss; Oxolinic Acid; Quinolones; Yersinia ruckeri	2004
Relationship between gyrA mutations and quinolone resistance in Flavobacterium psychrophilum isolates. Applied and environmental microbiology, 2004, Volume: 70, Issue:7 Topics: Amino Acid Sequence; DNA Gyrase; Drug Resistance, Bacterial; Flavobacterium; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nalidixic Acid; Oxolinic Acid; Polymerase Chain Reaction	2004
Micellar electrokinetic chromatography for determination of drug partition in phospholipids. Farmaco (Societa chimica italiana : 1989), 2005, Volume: 60, Issue:1 Topics: Anti-Infective Agents; Chromatography, Micellar Electrokinetic Capillary; Nalidixic Acid; Oxolinic Acid; Phospholipids; Pipemidic Acid	2005
Vibrational spectroscopic characterization of fluoroquinolones. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 61, Issue:7 Topics: Aza Compounds; Cinoxacin; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Enoxacin; Enzyme Inhibitors; Fluoroquinolones; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Models, Theoretical; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxolinic Acid; Quinolines; Quinolones; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Ultraviolet Rays; Vibration; Water	2005
Synthesis of amino acid derivatives of quinolone antibiotics. Organic & biomolecular chemistry, 2009, Jun-07, Volume: 7, Issue:11 Topics: Amino Acids; Anti-Bacterial Agents; Cinoxacin; Fluoroquinolones; Nalidixic Acid; Oxolinic Acid; Quinolines; Triazoles	2009
Resistance phenotypes and genotypes among multiple-antimicrobial-resistant Salmonella enterica subspecies enterica serovar Choleraesuis strains isolated between 2008 and 2012 from slaughter pigs in Okinawa Prefecture, Japan. The Journal of veterinary medical science, 2015, Volume: 77, Issue:6 Topics: Abattoirs; Ampicillin; Animals; Base Sequence; DNA Gyrase; DNA Primers; DNA Topoisomerase IV; Drug Resistance, Microbial; Genes, Bacterial; Genotype; Gentamicins; Islands; Japan; Microbial Sensitivity Tests; Molecular Sequence Data; Nalidixic Acid; Oxolinic Acid; Oxytetracycline; Phenotype; Salmonella enterica; Sequence Analysis, DNA; Species Specificity; Streptomycin; Sulfamethoxazole; Swine; Swine Diseases	2015