nalidixic acid and fluorouracil

nalidixic acid has been researched along with fluorouracil in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's1 (5.26)18.2507
2000's2 (10.53)29.6817
2010's8 (42.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ashenden, S; Bender, A; Cokol, M; Karakoc, I; Kuru, N; Mason, DJ; Meral, S; Stott, I; Weinstein, ZB1
Davies, J; Schindler, D1
Heinonen, J; Kukko, E1
MacNaughton, AW; Winder, FG1
Kaasch, J; Kaasch, M; Quiñones, A1
Donch, J; Green, MH; Greenberg, J1
Abramson, IJ; Smibert, RM1
Kukko, E; Saarento, H1
Arking, R; Kalata, K; Parente, A1
Dahan-Grobgeld, E; Degani, H; Eichenbaum, Z; Livneh, Z; Maretzek, AF; Polak-Charcon, S1

Reviews

2 review(s) available for nalidixic acid and fluorouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Inhibitors of macromolecular synthesis in yeast.
    Methods in cell biology, 1975, Volume: 12

    Topics: Acriflavine; Amphotericin B; Anisomycin; Anti-Bacterial Agents; Antineoplastic Agents; Cycloheximide; Dactinomycin; Daunorubicin; Deoxyadenosines; Depression, Chemical; DNA; Ethidium; Fluorouracil; Fungal Proteins; Hydroxyurea; Mitomycins; Nalidixic Acid; Phenazines; Phenylethyl Alcohol; Porfiromycin; Puromycin; RNA; Saccharomyces cerevisiae; Streptonigrin; Sulfanilamides; Triaziquone; Trichothecenes; Uracil

1975

Other Studies

17 other study(ies) available for nalidixic acid and fluorouracil

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure.
    Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9

    Topics: Anti-Bacterial Agents; Drug Interactions; Molecular Structure

2017
Partial inhibition of DNA synthesis gives rise to increase in the level of inorganic pyrophosphatase in the growing cells of Escherichia coli.
    Chemico-biological interactions, 1977, Volume: 17, Issue:1

    Topics: Depression, Chemical; DNA, Bacterial; Escherichia coli; Fluorouracil; Mitomycins; Nalidixic Acid; Pyrophosphatases; Thymine; Trimethoprim

1977
Increased DNA polymerase and ATP-dependent deoxyribonuclease activities following DNA damages in mycobacterium smegmatis.
    Molecular & general genetics : MGG, 1977, Feb-15, Volume: 150, Issue:3

    Topics: Acridines; Adenosine Triphosphate; Bacterial Proteins; Caffeine; Deoxyribonucleases; DNA-Directed DNA Polymerase; DNA, Bacterial; Ethidium; Ethyl Methanesulfonate; Fluorouracil; Mechlorethamine; Methyl Methanesulfonate; Mitomycins; Mutation; Mycobacterium; Nalidixic Acid; Proflavine; Ultraviolet Rays

1977
Expression of the dnaN and dnaQ genes of Escherichia coli is inducible by mitomycin C.
    Molecular & general genetics : MGG, 1989, Volume: 219, Issue:1-2

    Topics: DNA Damage; DNA Polymerase III; DNA Repair; DNA-Directed DNA Polymerase; Enzyme Induction; Escherichia coli; Fluorouracil; Gene Expression Regulation, Enzymologic; Mitomycin; Mitomycins; Mutation; Nalidixic Acid; SOS Response, Genetics

1989
Effect of inhibitors of DNA synthesis of UV-sensitive derivatives of Escherichia coli strain K-12.
    Mutation research, 1970, Volume: 9, Issue:2

    Topics: DNA; Drug Resistance, Microbial; Escherichia coli; Fluorouracil; Nalidixic Acid; Radiation Effects; Recombination, Genetic; Starvation; Thymine; Ultraviolet Rays

1970
Inhibition of growth of treponemes by antimicrobial agents.
    The British journal of venereal diseases, 1971, Volume: 47, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Benzofurans; Coloring Agents; Drug Resistance, Microbial; Feces; Fluorouracil; Furazolidone; Humans; Methenamine; Mouth; Muramidase; Nalidixic Acid; Nitrofurazone; Rabbits; Sulfonamides; Sulfonic Acids; Swine; Thallium; Tolonium Chloride; Treponema; Uracil

1971
Diphosphate concentration does not correlate with the level of inorganic diphosphatase in Escherichia coli.
    Folia microbiologica, 1984, Volume: 29, Issue:4

    Topics: Diphosphates; DNA Replication; Escherichia coli; Fluorouracil; Inorganic Pyrophosphatase; Kinetics; Mutation; Nalidixic Acid; Pyrophosphatases; Transcription, Genetic; Uracil

1984
Effect of DNA inhibitors upon DNA synthesis and development of Drosophila embryos.
    The Journal of experimental zoology, 1980, Volume: 212, Issue:2

    Topics: Age Factors; Animals; Arabinonucleotides; Cytidine Monophosphate; DNA; Drosophila melanogaster; Fluorouracil; Mitomycins; Nalidixic Acid; Thymidine; Time Factors

1980
Reversible induction of ATP synthesis by DNA damage and repair in Escherichia coli. In vivo NMR studies.
    The Journal of biological chemistry, 1998, Nov-13, Volume: 273, Issue:46

    Topics: Adenosine Triphosphate; Anti-Infective Agents; Bacterial Proteins; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Exodeoxyribonuclease V; Exodeoxyribonucleases; Fluorouracil; Magnetic Resonance Spectroscopy; Nalidixic Acid; Serine Endopeptidases; SOS Response, Genetics

1998