nalidixic acid and clozapine

nalidixic acid has been researched along with clozapine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's5 (31.25)18.2507
2000's1 (6.25)29.6817
2010's9 (56.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Marsden, CA; Rivest, R1
Defife, K; Gudelsky, GA; Nash, JF; Nwajei, EE1
Jolicoeur, FB; Marsden, CA; Rivest, R1
Brougham, LR; Conway, PG; Ellis, DB1
Compton, DR; Johnson, KM1
Mueller, K1

Reviews

1 review(s) available for nalidixic acid and clozapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for nalidixic acid and clozapine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Differential effects of amfonelic acid on the haloperidol- and clozapine-induced increase in extracellular DOPAC in the nucleus accumbens and the striatum.
    Synapse (New York, N.Y.), 1992, Volume: 10, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clozapine; Corpus Striatum; Drug Interactions; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Male; Membrane Potentials; Nalidixic Acid; Naphthyridines; Nucleus Accumbens; Rats; Rats, Inbred Strains; Ritanserin; Time Factors

1992
Effects of amfonelic acid and GBR 12909 on the haloperidol- and clozapine-induced activation of dopamine neurons.
    Psychopharmacology bulletin, 1992, Volume: 28, Issue:3

    Topics: Animals; Clozapine; Dopamine; Haloperidol; Male; Nalidixic Acid; Naphthyridines; Neurons; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley

1992
Use of amfonelic acid to discriminate between classical and atypical neuroleptics and neurotensin: an in vivo voltammetric study.
    Brain research, 1991, Mar-22, Volume: 544, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Cerebral Ventricles; Clozapine; Corpus Striatum; Electrochemistry; Haloperidol; Injections, Intraventricular; Male; Nalidixic Acid; Naphthyridines; Neurotensin; Perphenazine; Rats; Rats, Inbred Strains; Thioridazine

1991
Effect of ritanserin on the interaction of amfonelic acid and neuroleptic-induced striatal dopamine metabolism.
    Neuropharmacology, 1991, Volume: 30, Issue:10

    Topics: Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Clozapine; Corpus Striatum; Dopamine; Haloperidol; Male; Nalidixic Acid; Naphthyridines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Substantia Nigra; Synaptic Transmission

1991
Effects of acute and chronic clozapine and haloperidol on in vitro release of acetylcholine and dopamine from striatum and nucleus accumbens.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:2

    Topics: Acetylcholine; Amphetamine; Animals; Clozapine; Corpus Striatum; Dibenzazepines; Dopamine; Electric Stimulation; Haloperidol; In Vitro Techniques; Male; Nalidixic Acid; Naphthyridines; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Tetrahydronaphthalenes

1989
Locomotor stereotypy is produced by methylphenidate and amfonelic acid and reduced by haloperidol but not clozapine or thioridazine.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:1

    Topics: Animals; Antipsychotic Agents; Clozapine; Haloperidol; Male; Methylphenidate; Motor Activity; Nalidixic Acid; Naphthyridines; Rats; Rats, Wistar; Stereotyped Behavior; Thioridazine

1993