nafoxidine has been researched along with tamoxifen in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 60 (72.29) | 18.7374 |
| 1990's | 18 (21.69) | 18.2507 |
| 2000's | 4 (4.82) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Kon, OL; Ng, SC; Sim, KY; Teo, CC | 1 |
| Fiechtner, B; Glossmann, H; Hoffmann, RD; Laggner, C; Langer, T; Moebius, FF; Poles, G; Schieferer, C | 1 |
| Ernst, B; Lill, MA; Vedani, A; Winiger, F | 1 |
| Anantpadma, M; Cheng, H; Cooper, L; Davey, RA; Dye, K; Li, Y; Medegan Fagla, B; Nowar, R; Rong, L; Schafer, A; Shen, Z; Thatcher, GRJ; Xiong, R | 1 |
| Braunsberg, H | 1 |
| Carbone, PP | 1 |
| Tagnon, HJ | 1 |
| Davis, HL; Legha, SS; Muggia, FM | 1 |
| Etgen, AM | 2 |
| Görlich, M; Heise, E; Kerpel-Fronius, S; Számel, I | 1 |
| Horwitz, KB; McGuire, WL | 3 |
| Capony, F; Rochefort, H | 1 |
| McIntosh, IH; Thynne, GS | 1 |
| Dodge, AH | 1 |
| Davenport, CE; Fletcher, WS; Kraybill, WG; Leung, BS; Moseson, DL; Sasaki, GH | 1 |
| Horwitz, KB; Koseki, Y; McGuire, WL | 1 |
| Deboel, MC; Heuson, JC; Leclercq, G; Longeval, E; Mattheiem, WH; Sylvester, RJ | 1 |
| Legha, S; Muggia, FM | 1 |
| Bulger, WH; Kupfer, D | 1 |
| Carter, SK; Legha, SS | 1 |
| Bolan, G; Huff, K; Lippman, M | 1 |
| Eskenazi, F; Gorins, A | 1 |
| Bern, HA; Chou, YC; Iguchi, T | 1 |
| Cantabrana, B; Hidalgo, A | 1 |
| Gottardis, MM; Jordan, VC; Satyaswaroop, PG | 1 |
| Carvalho, AP; Lopes, MC; Tavares, MC; Vale, MG | 1 |
| Iguchi, T; Irisawa, S; Kusunoki, S; Takasugi, N; Uesugi, Y | 1 |
| Bauch, HJ | 1 |
| Courion-Guichardaz, C; Fanidi, A; Fayard, JM; Laugier, C; Pageaux, JF | 1 |
| Hayashi, K; Kida, N; Mori, K; Yoshimura, T | 1 |
| Barrera, G; Dianzani, MU; Farina, A; Ferretti, C; Frati, L; Gulino, A; Paradisi, L; Parola, M; Screpanti, I; Vacca, A | 1 |
| Giambiagi, N; Pasqualini, JR; Sumida, C | 1 |
| Bayard, F; Beauregard, G; Fargin, A; Faye, JC; le Maire, M; Potier, M | 1 |
| Beattie, CW; Hitselberger, MH; Schleicher, RL | 1 |
| Nomura, Y; Takaeko, F; Tashiro, H | 1 |
| Bover, L; Bravo, AI; Dain, L; Guman, N; Mordoh, J; Podhajcer, OL | 1 |
| Dey, SK; Huet, YM | 1 |
| Hertner, T; Jiricny, J; Jost, JP; Moncharmont, B; Saluz, H | 1 |
| Ali, AM; Khar, A | 1 |
| Baldi, A; Medrano, EE; Santa Cruz, AR | 1 |
| Forsberg, JG | 1 |
| Ariens, AT; Labruyère, W; Lindeman, J; van Marle, J; van Weeren-Kramer, J | 1 |
| Flandroy, L; Galand, P | 1 |
| Auricchio, F; Castoria, G; Migliaccio, A | 1 |
| Burghardt, RC; Kurten, R; Mitchell, PA | 1 |
| Hsueh, AJ; Jia, XC; Jones, PB; Welsh, TH; Zhuang, LZ | 1 |
| Brown, AM; Chambon, P; Krust, A; Lippman, ME; May, FE; Rochefort, H; Westley, B | 1 |
| Lax, ER; Peetz, A; Plasczyk, H; Rumstadt, F; Schriefers, H | 1 |
| Boldt, DH; Estrada, P; Osborne, CK | 1 |
| Gulino, A; Pasqualini, JR; Screpanti, I; Sumida, C | 1 |
| Attardi, B | 2 |
| Gelly, C; Gulino, A; Nguyen, BL; Pasqualini, JR; Sumida, C; Tardy, J | 1 |
| Katzenellenbogen, BS; Kneifel, MA | 1 |
| Devi, PK | 1 |
| Majid, E; Senior, J | 1 |
| Clark, JH; Markaverich, BM; Panko, WB; Syne, JS | 1 |
| Drutz, DJ; Huppert, M; McGuire, WL; Sun, SH | 1 |
| Major, FJ; Moore, GE; Myers, AM | 1 |
| Clark, JH; Guthrie, SC; McCormack, SA | 1 |
| Stoll, BA | 1 |
| Lippman, ME; Monaco, ME; Strobl, JS | 1 |
| Clark, JH; McCormack, SA | 1 |
| Gulino, A; Pasqualini, JR | 1 |
| Brooks, SC; Saunders, DE; Singhakowinta, A; Vaitkevicius, VK | 1 |
| Chauhan, SC; Dwivedi, A; Kamboj, VP; Singh, MM; Trivedi, RN | 1 |
| Collins, DC; Gagliardi, A | 1 |
| Halliwell, B; Wiseman, H | 1 |
| Wiseman, H | 1 |
| Dwivedy, I; Katzenellenbogen, JA; O'Neil, JP; Ray, S; Tandon, A; Wilson, SR | 1 |
| Allan, GF; Beekman, JM; O'Malley, BW; Tsai, MJ; Tsai, SY | 1 |
| Bryant, HU; Rippy, MK; Sato, M | 1 |
| Lee, YS; Wurster, RD | 1 |
| Logie, C; Nichols, M; Rientjes, JM; Stewart, AF | 1 |
| Arnold, SF; Chen, J; Jin, L; McLachlan, JA; Tran, DQ | 1 |
| Chiappetta, C; Hyder, SM; Stancel, GM | 1 |
| Jeannin, E; Liu, JW; Picard, D | 1 |
| Prasad, MR; Sankaran, MS | 1 |
| Atlas, L; Dvilansky, A; Hayon, T; Levy, E; Nathan, I; Shpilberg, O | 1 |
| Durmaz, R; Kabadere, S; Oztopçu, P; Uyar, R; Yaz, G | 1 |
6 review(s) available for nafoxidine and tamoxifen
| Article | Year |
|---|---|
Antiestrogens in treatment of breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Clomiphene; Estrogen Antagonists; Ethinyl Estradiol; Female; Humans; Menopause; Middle Aged; Nafoxidine; Neoplasm Metastasis; Pyrrolidines; Stilbenes; Tamoxifen | 1977 |
Hormonal therapy of breast cancer: new approaches and concepts.
Topics: Adrenalectomy; Breast Neoplasms; Castration; Clomiphene; Ergotamines; Estrogen Antagonists; Female; Humans; Hypophysectomy; Levodopa; Nafoxidine; Neoplasm Metastasis; Prolactin; Receptors, Estrogen; Tamoxifen | 1978 |
[Cytostatic drugs. 2: Bleomycins, antimetabolites, mitotic spindle poisons, L-asparaginase and anti-hormones].
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Asparaginase; Bleomycin; Cell Survival; DNA, Neoplasm; Humans; Nafoxidine; Spindle Apparatus; Tamoxifen; Tumor Cells, Cultured | 1989 |
Pharmacodynamic and biological effects of anti-estrogens in different models.
Topics: Animals; Antibodies, Monoclonal; Cell Division; Clomiphene; DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Female; Growth Substances; Humans; Lipoproteins, LDL; Liver; Nafoxidine; Nitromifene; Polyunsaturated Alkamides; Pyrrolidines; Receptors, Estrogen; Receptors, Progesterone; Species Specificity; Structure-Activity Relationship; Tamoxifen; Thiophenes; Uterus | 1988 |
Studies on mechanisms of estrogen and antiestrogen action in human breast cancer.
Topics: Breast Neoplasms; Cell Line; Cell Nucleus; Cytoplasm; Dactinomycin; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Nafoxidine; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1980 |
Antiestrogens.
Topics: Animals; Centchroman; Chemical Phenomena; Chemistry; Clomiphene; Estrogen Antagonists; Humans; Nafoxidine; Tamoxifen | 1981 |
1 trial(s) available for nafoxidine and tamoxifen
| Article | Year |
|---|---|
Antiestrogens in treatment of breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Clomiphene; Estrogen Antagonists; Ethinyl Estradiol; Female; Humans; Menopause; Middle Aged; Nafoxidine; Neoplasm Metastasis; Pyrrolidines; Stilbenes; Tamoxifen | 1977 |
77 other study(ies) available for nafoxidine and tamoxifen
| Article | Year |
|---|---|
Synthesis of 2-(p-chlorobenzyl)-3-aryl-6-methoxybenzofurans as selective ligands for antiestrogen-binding sites. Effects on cell proliferation and cholesterol synthesis.
Topics: Benzofurans; Binding Sites; Binding, Competitive; Cell Division; Cell Line; Cholesterol; Estrogen Antagonists; Humans; Ligands; Receptors, Estrogen; Thymidine | 1992 |
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.
Topics: Animals; Carrier Proteins; Databases, Factual; Guinea Pigs; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Isomerism; Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, sigma; Saccharomyces cerevisiae; Sigma-1 Receptor; Steroid Isomerases | 2005 |
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics | 2005 |
Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors.
Topics: Antiviral Agents; Cell Line, Tumor; Drug Evaluation, Preclinical; Filoviridae; Humans; Ligands; Membrane Fusion; Models, Biological; Receptors, Estrogen; Structure-Activity Relationship | 2020 |
Factors influencing the estimation of oestrogen receptors in human malignant breast tumours.
Topics: Breast Neoplasms; Cytosol; Estradiol; Freezing; Humans; Nafoxidine; Nitromifene; Receptors, Cell Surface; Sulfhydryl Reagents; Tamoxifen | 1975 |
Editorial: Antiestrogens and breast cancer treatment.
Topics: Breast Neoplasms; Estrogen Antagonists; Female; Humans; Nafoxidine; Receptors, Cell Surface; Tamoxifen | 1975 |
Antiestrogens: effects of tamoxifen, nafoxidine, and CI-628 on sexual behavior, cytoplasmic receptors, and nuclear binding of estrogen.
Topics: Animals; Brain; Cell Nucleus; Estradiol; Estrogen Antagonists; Female; Nafoxidine; Nitromifene; Pyrrolidines; Rats; Receptors, Estrogen; Sexual Behavior, Animal; Tamoxifen; Time Factors | 1979 |
Chemotherapeutic agents and estradiol receptor binding capacity.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Dianhydrogalactitol; Estradiol; Female; Fluorouracil; Humans; In Vitro Techniques; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mechlorethamine; Nafoxidine; Rats; Receptors, Estrogen; Tamoxifen; Uterus | 1979 |
Estrogen control of progesterone receptor induction in human breast cancer: role of nuclear estrogen receptor.
Topics: Breast Neoplasms; Cell Line; Cell Nucleus; Cytoplasm; Estradiol; Female; Humans; Nafoxidine; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1979 |
Estradiol dependent decrease of binding inhibition by anti-estrogens (a possible test of receptor activation).
Topics: Animals; Binding, Competitive; Cattle; Cytosol; Estradiol; Estrogen Antagonists; Female; Kinetics; Nafoxidine; Receptors, Estrogen; Stilbenes; Tamoxifen; Temperature; Uterus | 1977 |
Tumour stimulation by anti-oestrogens.
Topics: Adult; Breast Neoplasms; Female; Humans; Middle Aged; Nafoxidine; Pyrrolidines; Recurrence; Tamoxifen | 1977 |
Fine structural, G-6-PD isoenzyme, and HaLV gs antigen studies of poly I/C and antiestrogen treated DES-induced hamster renal tumors.
Topics: Animals; Antigens, Neoplasm; Cricetinae; Diethylstilbestrol; Glucosephosphate Dehydrogenase; Isoenzymes; Kidney Neoplasms; Mesocricetus; Nafoxidine; Neoplasms, Experimental; Poly I-C; Tamoxifen | 1977 |
The use of antiestrogens tamoxifen and nafoxidine in the treatment of human breast cancer in correlation with estrogen receptor values. A phase II study.
Topics: Breast Neoplasms; Female; Humans; Nafoxidine; Pyrrolidines; Receptors, Estrogen; Tamoxifen | 1978 |
Nuclear mechanisms of estrogen action. Effects of estradiol and anti-estrogens on estrogen receptors and nuclear receptor processing.
Topics: Binding, Competitive; Cell Line; Cell Nucleus; Cytosol; Estradiol; Kinetics; Nafoxidine; Pyrrolidines; Receptors, Estrogen; Tamoxifen | 1978 |
Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen.
Topics: Breast Neoplasms; Cells, Cultured; Estradiol; Estrogen Antagonists; Humans; Nafoxidine; Receptors, Progesterone; Tamoxifen | 1978 |
Significance of quantitative assessment of estrogen receptors for endocrine therapy in advanced breast cancer.
Topics: Adrenalectomy; Adult; Aged; Androgens; Breast Neoplasms; Castration; Ethinyl Estradiol; Female; Humans; Middle Aged; Nafoxidine; Prognosis; Receptors, Estrogen; Statistics as Topic; Tamoxifen | 1977 |
Letter: Antiestrogens in the treatment of cancer.
Topics: Breast Neoplasms; Clomiphene; Estrogen Antagonists; Female; Hormone Antagonists; Humans; Male; Nafoxidine; Neoplasms; Tamoxifen | 1976 |
Induction of uterine ornithine decarboxylase (ODC) by antiestrogens. Inhibition of estradiol-mediated induction of ODC: a possible mechanism of action of antiestrogens.
Topics: Animals; Carboxy-Lyases; Castration; Enzyme Induction; Estradiol; Female; Nafoxidine; Ornithine Decarboxylase; Pyrrolidines; Rats; Stilbenes; Tamoxifen; Time Factors; Uterus | 1976 |
Antiestrogens in the treatment of breast cancer.
Topics: Breast Neoplasms; Clomiphene; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Humans; Nafoxidine; Tamoxifen | 1976 |
Interactions of antiestrogens with human breast cancer in long-term tissue culture.
Topics: Animals; Cell Line; Clomiphene; Estradiol; Estrogen Antagonists; Estrogens; Humans; Mammary Neoplasms, Experimental; Nafoxidine; Pyrrolidines; Receptors, Estrogen; Stilbenes; Tamoxifen; Thymidine | 1976 |
[Further aspects of hormone therapy of metastatic breast cancer].
Topics: Breast Neoplasms; Estrogen Antagonists; Female; Humans; Nafoxidine; Prolactin; Pyrrolidines; Stilbenes; Tamoxifen | 1975 |
Effects of antiestrogens on adult and neonatal mouse reproductive organs.
Topics: Animals; Animals, Newborn; Body Weight; Clomiphene; Estrogen Antagonists; Female; Genitalia, Female; Genitalia, Male; Male; Mice; Mice, Inbred C57BL; Nafoxidine; Organ Size; Ovariectomy; Ovary; Piperidines; Raloxifene Hydrochloride; Tamoxifen; Trifluoperazine; Uterus; Vagina | 1992 |
Effects of nonsteroidal antiestrogens in the in vitro rat uterus.
Topics: Animals; Calcium; Clomiphene; Estrogen Antagonists; Ethamoxytriphetol; Female; In Vitro Techniques; Nafoxidine; Rats; Rats, Wistar; Tamoxifen; Uterine Contraction; Uterus | 1992 |
Tamoxifen-stimulated growth of human endometrial carcinoma.
Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Clomiphene; Enclomiphene; Endometrium; Estradiol; Estrogen Antagonists; Female; Humans; Mice; Mice, Inbred BALB C; Nafoxidine; Neoplasm Transplantation; Piperidines; Polyunsaturated Alkamides; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Uterine Neoplasms | 1991 |
Characterization of estrogen and antiestrogen binding to the cytosol and microsomes of breast tumors.
Topics: Binding, Competitive; Breast Neoplasms; Clomiphene; Cytosol; Enclomiphene; Estrogen Antagonists; Estrogens; Humans; Kinetics; Microsomes; Nafoxidine; Tamoxifen | 1991 |
Abnormal development of the os penis in male mice treated neonatally with tamoxifen.
Topics: Animals; Animals, Newborn; Cartilage; Clomiphene; Estrogen Antagonists; Infections; Male; Mice; Nafoxidine; Penis; Tamoxifen; Time Factors | 1990 |
Effects of tamoxifen, tamoxifen metabolites, and nafoxidine on adenosine 3',5'-monophosphate phosphodiesterase: correlations with growth inhibitory activities but not estrogen receptor affinities.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Estradiol; Female; Kinetics; Nafoxidine; Oviducts; Pyrrolidines; Quail; Receptors, Estrogen; Reference Values; Structure-Activity Relationship; Tamoxifen | 1989 |
Hormonal regulation of synthesis and secretion of pS2 protein relevant to growth of human breast cancer cells (MCF-7).
Topics: Androgens; Breast Neoplasms; Cell Division; Cycloheximide; Dactinomycin; DNA, Neoplasm; Estrogens; Humans; In Vitro Techniques; Nafoxidine; Neoplasm Proteins; Progesterone; Proteins; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1989 |
Structure-activity relationships of calmodulin antagonism by triphenylethylene antiestrogens.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Calmodulin; Estradiol; Estrogen Antagonists; Nafoxidine; Stilbenes; Structure-Activity Relationship; Tamoxifen | 1986 |
Solubilization of a tamoxifen-binding protein. Assessment of its molecular mass.
Topics: Animals; Centrifugation, Density Gradient; Cholic Acids; Chromatography, High Pressure Liquid; Detergents; Female; Macromolecular Substances; Microsomes; Molecular Weight; Nafoxidine; Nitromifene; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Estrogen; Solubility; Tamoxifen; Uterus | 1988 |
Inhibition of hamster melanoma growth by estrogen.
Topics: Animals; Cell Division; Cricetinae; Cytosol; Estradiol; Female; Male; Melanoma, Experimental; Mice; Mice, Nude; Monophenol Monooxygenase; Nafoxidine; Receptors, Estrogen; Tamoxifen | 1987 |
[Effects of antiestrogens and medroxyprogesterone acetate on the clonogenic growth of tamoxifen-sensitive and resistant human breast cancer cells].
Topics: Breast Neoplasms; Cell Division; Cell Line; Cells, Cultured; Drug Resistance; Estrogen Antagonists; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Nafoxidine; Tamoxifen | 1985 |
In vitro analysis of the cellular proliferative response to 17-beta-estradiol of human breast cancer.
Topics: Breast Neoplasms; Carcinoembryonic Antigen; Cell Division; Diethylstilbestrol; DNA Replication; DNA, Neoplasm; Estradiol; Humans; Nafoxidine; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Receptors, Estrogen; Stimulation, Chemical; Tamoxifen; Tumor Cells, Cultured | 1988 |
Role of early and late oestrogenic effects on implantation in the mouse.
Topics: Animals; Clomiphene; Embryo Implantation; Embryo Implantation, Delayed; Estradiol; Estriol; Estrogens; Female; Mice; Mice, Inbred Strains; Nafoxidine; Nitromifene; Organ Size; Ovariectomy; Progesterone; Pyrrolidines; Tamoxifen; Thiophenes; Uterus | 1987 |
In vitro secondary activation (memory effect) of avian vitellogenin II gene in isolated liver nuclei.
Topics: Animals; Calcium; Calmodulin; Cell Nucleus; Chickens; Cytoplasm; Estradiol; Flupenthixol; Gene Expression Regulation; Kinetics; Liver; Male; Nafoxidine; Polyamines; Protein Kinases; Quercetin; Receptors, Estradiol; RNA, Messenger; Tamoxifen; Transcription, Genetic; Vitellogenins | 1986 |
Serum protects HeLa cells from antiestrogen effects in culture.
Topics: Animals; Blood Physiological Phenomena; Cattle; Cell Line; Cell Survival; Culture Media; Estrogen Antagonists; Fetus; HeLa Cells; Humans; Nafoxidine; Pyrrolidines; Serum Albumin, Bovine; Tamoxifen | 1987 |
Dolichol-sugar derivative synthesis in human breast cancer cell line (T47D). Effects of estrogens and antiestrogens.
Topics: Breast Neoplasms; Cell Line; Chromatography, Ion Exchange; Chromatography, Thin Layer; Estradiol; Female; Humans; Nafoxidine; Polyisoprenyl Phosphate Monosaccharides; Polyisoprenyl Phosphate Sugars; Pyrrolidines; Tamoxifen | 1985 |
Treatment with different antiestrogens in the neonatal period and effects in the cervicovaginal epithelium and ovaries of adult mice: a comparison to estrogen-induced changes.
Topics: Animals; Cervix Uteri; Diethylstilbestrol; Estradiol; Estrogen Antagonists; Ethamoxytriphetol; Female; Genitalia, Female; Isomerism; Mice; Nafoxidine; Ovary; Pregnancy; Prenatal Exposure Delayed Effects; Tamoxifen; Vagina | 1985 |
Estrogen receptors in human breast cancer. I. Specificity of the histochemical localization of estrogen receptors using an estrogen-albumin FITC complex.
Topics: Animals; Breast Neoplasms; Cattle; Cell Transformation, Neoplastic; Estrogens; Fluorescein-5-isothiocyanate; Fluoresceins; Frozen Sections; Histocytochemistry; Humans; Nafoxidine; Receptors, Estrogen; Serum Albumin, Bovine; Tamoxifen; Thiocyanates; Time Factors | 1982 |
In vitro stimulation by estrogen of guanosine 3',5'-monophosphate accumulation in incubated rat uterus.
Topics: Animals; Dose-Response Relationship, Drug; Estradiol; Female; Guanine Nucleotides; Guanosine Monophosphate; In Vitro Techniques; Nafoxidine; Progesterone; Rats; Tamoxifen; Testosterone; Uterus | 1980 |
Dephosphorylation of oestradiol nuclear receptor in vitro. A hypothesis on the mechanism of action of non-steroidal anti-oestrogens.
Topics: Animals; Cattle; Cell Nucleus; Cytosol; Estradiol; Female; Half-Life; In Vitro Techniques; Mice; Nafoxidine; Phosphoric Monoester Hydrolases; Pyrrolidines; Receptors, Estradiol; Receptors, Estrogen; Tamoxifen; Uterus | 1981 |
Gap junction modulation in rat uterus. II. Effects of antiestrogens on myometrial and serosal cells.
Topics: Animals; Clomiphene; Enclomiphene; Estrogen Antagonists; Female; Intercellular Junctions; Isomerism; Microscopy, Electron; Myometrium; Nafoxidine; Nitromifene; Rats; Tamoxifen; Uterus | 1984 |
Disparate effects of triphenylethylene antiestrogens on estrogen and progestin biosyntheses by cultured rat granulosa cells.
Topics: Animals; Aromatase; Clomiphene; Diethylstilbestrol; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Granulosa Cells; Hydroxyprogesterones; Nafoxidine; Pregnenolone; Progesterone; Progestins; Pyrrolidines; Rats; Rats, Inbred Strains; Tamoxifen | 1984 |
Effects of antiestrogens on the estrogen-regulated pS2 RNA and the 52- and 160-kilodalton proteins in MCF7 cells and two tamoxifen-resistant sublines.
Topics: Breast Neoplasms; Cell Line; Drug Resistance; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Molecular Weight; Nafoxidine; Neoplasm Proteins; Pyrrolidines; RNA, Messenger; Tamoxifen; Transcription, Genetic | 1984 |
Antagonistic action of estrogens, flutamide, and human growth hormone on androgen-induced changes in the activities of some enzymes of hepatic steroid metabolism in the rat.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen Antagonists; Anilides; Animals; Castration; Estrogen Antagonists; Estrogens; Female; Flutamide; Growth Hormone; Male; Microsomes, Liver; Nafoxidine; Rats; Rats, Inbred Strains; Steroids; Tamoxifen | 1983 |
Human breast cancer cell cycle synchronization by estrogens and antiestrogens in culture.
Topics: Breast Neoplasms; Cell Cycle; Cell Line; Culture Media; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Nafoxidine; Pyrrolidines; Tamoxifen | 1984 |
Anti-estrogens in fetal and newborn target tissues.
Topics: Acetylation; Animals; Animals, Newborn; Estradiol; Estrogen Antagonists; Female; Guinea Pigs; Histones; Nafoxidine; Pregnancy; Receptors, Progesterone; Tamoxifen; Thymus Gland; Uterus | 1984 |
Multiple forms of nuclear estrogen receptor in the hypothalamus and pituitary after in vitro exchange with [3H]estradiol or [3H]hydroxytamoxifen.
Topics: Animals; Cell Nucleus; Centrifugation, Density Gradient; Estradiol; Female; Hypothalamus; Nafoxidine; Pituitary Gland; Receptors, Estrogen; Tamoxifen | 1983 |
Multiple forms of nuclear estrogen receptor in the immature rat uterus after in vitro exchange with [3H]estradiol or [3H] antiestrogens.
Topics: Animals; Cell Nucleus; Centrifugation, Density Gradient; Estradiol; Estrogen Antagonists; Female; Nafoxidine; Rats; Receptors, Estrogen; Stilbenes; Tamoxifen; Uterus | 1983 |
[Biological action of estrogens and antiestrogens in the fetal uterus of the guinea pig: uterotrophic effect and action on progesterone receptors].
Topics: Animals; Estradiol; Female; Guinea Pigs; Nafoxidine; Organ Size; Pregnancy; Pyrrolidines; Receptors, Progesterone; Tamoxifen; Uterus | 1980 |
Comparative effects of estrogen and antiestrogen on plasma renin substrate levels and hepatic estrogen receptors in the rat.
Topics: Angiotensinogen; Angiotensins; Animals; Cell Nucleus; Cytoplasm; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Liver; Nafoxidine; Nitromifene; Rats; Receptors, Estrogen; Tamoxifen; Time Factors | 1981 |
Anti-oestrogen modification of uterine responses to oestrogen in the rat.
Topics: Animals; Body Water; Castration; Estradiol; Female; Nafoxidine; Organ Size; Rats; Rats, Inbred Strains; Regional Blood Flow; Tamoxifen; Uterus | 1982 |
Estrogen binding sites in the nucleus of normal and malignant human tissue: characteristics of the multiple nuclear binding sites.
Topics: Breast Neoplasms; Cell Nucleus; Cytosol; DNA, Neoplasm; Estradiol; Female; Humans; Kinetics; Myometrium; Nafoxidine; Polysorbates; Receptors, Estrogen; Reference Values; Tamoxifen; Uterus | 1982 |
Human sex hormones stimulate the growth and maturation of Coccidioides immitis.
Topics: Coccidioides; Estradiol; Estrogen Antagonists; Humans; Nafoxidine; Progesterone; Species Specificity; Spores, Fungal; Tamoxifen; Testosterone | 1981 |
Advanced ovarian carcinoma: response to antiestrogen therapy.
Topics: Adult; Cystadenocarcinoma; Estrogen Antagonists; Female; Humans; Megestrol; Middle Aged; Nafoxidine; Neoplasm Metastasis; Ovarian Neoplasms; Tamoxifen | 1981 |
Differential effects of two estrogen antagonists on the development of masculine and feminine sexual behavior in hamsters.
Topics: Animals; Animals, Newborn; Cricetinae; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Male; Mesocricetus; Nafoxidine; Progesterone; Sex Factors; Sexual Behavior, Animal; Tamoxifen | 1981 |
Neonatal stimulation of the uterus by clomiphene, tamoxifen and nafoxidine: relationship to the development of reproductive tract abnormalities.
Topics: Animals; Animals, Newborn; Clomiphene; Estrogens; Female; Fetus; Genitalia, Female; Male; Nafoxidine; Pyrrolidines; Rats; Rats, Inbred Strains; Tamoxifen; Uterine Neoplasms; Uterus | 1981 |
Clinical experience with tamoxifen in advanced breast cancer.
Topics: Adult; Age Factors; Aged; Breast Neoplasms; Clomiphene; Drug Tolerance; Female; Humans; Hypercalcemia; Male; Middle Aged; Nafoxidine; Neoplasm Metastasis; Pregnancy; Prolactin; Receptors, Estrogen; Remission, Spontaneous; Tamoxifen; Thrombocytopenia | 1980 |
The role of intracellular equilibria and the effect of antiestrogens on estrogen-receptor dissociation kinetics from perfused cultures of human breast cancer cells.
Topics: Binding Sites; Breast Neoplasms; Cell Line; Clomiphene; Estradiol; Estriol; Female; Humans; Kinetics; Nafoxidine; Pyrrolidines; Receptors, Estrogen; Tamoxifen | 1980 |
The effect of clomid and other triphenylethylene derivatives during pregnancy and the neonatal period.
Topics: Animals; Animals, Newborn; Cell Nucleus; Cervix Uteri; Clomiphene; Cytosol; Female; Genitalia, Female; Nafoxidine; Oviducts; Pregnancy; Pregnancy, Animal; Pyrrolidines; Rats; Receptors, Estrogen; Reproduction; Tamoxifen; Uterus; Vagina | 1980 |
Specific binding and biological response of antiestrogens in the fetal uterus of the guinea pig.
Topics: Animals; Binding Sites; Binding, Competitive; Cytosol; Estradiol; Estrone; Female; Fetal Blood; Guinea Pigs; Nafoxidine; Organ Size; Pregnancy; Pyrrolidines; Receptors, Estrogen; Tamoxifen; Uterus | 1980 |
Relation of tumor content of estrogen and progesterone receptors with response of patient to endocrine therapy.
Topics: Breast Neoplasms; Diethylstilbestrol; Estrogen Antagonists; Female; Humans; Nafoxidine; Neoplasms, Hormone-Dependent; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1980 |
Time-related effects of a triphenylethylene antiestrogen on estrogen-induced changes in uterine weight, estrogen receptors, and endometrial sensitivity in rats.
Topics: Administration, Oral; Animals; Centchroman; Decidua; Dose-Response Relationship, Drug; Endometrium; Epithelium; Estradiol; Estrogen Antagonists; Female; Microscopy, Electron, Scanning; Nafoxidine; Organ Size; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen; Time Factors; Uterus | 1995 |
Inhibition of angiogenesis by antiestrogens.
Topics: Animals; Chick Embryo; Clomiphene; Dimethyl Sulfoxide; Dimethylformamide; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Fulvestrant; Heparin; Hydrocortisone; Nafoxidine; Neovascularization, Pathologic; Polyunsaturated Alkamides; Solubility; Tamoxifen | 1993 |
Tamoxifen and related compounds protect against lipid peroxidation in isolated nuclei: relevance to the potential anticarcinogenic benefits of breast cancer prevention and therapy with tamoxifen?
Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cell Nucleus; Estradiol; Estrogen Antagonists; Female; Humans; Lipid Peroxidation; Liver; Male; Nafoxidine; Polyunsaturated Alkamides; Rats; Rats, Wistar; Structure-Activity Relationship; Tamoxifen | 1994 |
The antioxidant action of a pure antioestrogen: ability to inhibit lipid peroxidation compared to tamoxifen and 17 beta-oestradiol and relevance to its anticancer potential.
Topics: Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Brain; Cattle; Estradiol; Ferric Compounds; Lipid Peroxidation; Male; Microsomes, Liver; Nafoxidine; Polyunsaturated Alkamides; Rats; Tamoxifen | 1994 |
An X-ray crystallographic study of the nonsteroidal contraceptive agent centchroman.
Topics: Centchroman; Crystallization; Crystallography, X-Ray; Estradiol; Iodides; Methylation; Molecular Conformation; Molecular Structure; Nafoxidine; Receptors, Estrogen; Stereoisomerism; Tamoxifen | 1994 |
Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain.
Topics: Animals; Baculoviridae; Base Sequence; Binding Sites; Chymotrypsin; Cold Temperature; DNA; Estradiol; Estrogens; Gene Expression Regulation; Humans; Molecular Sequence Data; Moths; Nafoxidine; Polyunsaturated Alkamides; Protein Conformation; Receptors, Estrogen; Recombinant Proteins; Sodium Fluoride; Tamoxifen; Transcription, Genetic; Transcriptional Activation; Transfection | 1993 |
Raloxifene, tamoxifen, nafoxidine, or estrogen effects on reproductive and nonreproductive tissues in ovariectomized rats.
Topics: Adipose Tissue; Animals; Bone Density; Estrogen Antagonists; Estrogens; Female; Lipid Metabolism; Nafoxidine; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Reproduction; Tamoxifen; Uterus | 1996 |
Bepridil enhances in vitro antitumor activity of antiestrogens in human brain tumor cells.
Topics: Bepridil; Brain Neoplasms; Calcium Channel Blockers; Cell Division; Clomiphene; Drug Synergism; Estrogen Antagonists; Humans; Nafoxidine; Tamoxifen; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
FLP recombinase/estrogen receptor fusion proteins require the receptor D domain for responsiveness to antagonists, but not agonists.
Topics: Amino Acid Sequence; Bacterial Outer Membrane Proteins; Diethylstilbestrol; DNA Nucleotidyltransferases; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens, Non-Steroidal; Fulvestrant; Hexestrol; HSP90 Heat-Shock Proteins; Humans; Ligands; Molecular Sequence Data; Nafoxidine; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Recombinant Fusion Proteins; Tamoxifen; Time Factors; Yeasts | 1997 |
Evaluation of clinical and environmental anti-estrogens with human estrogen receptor expressed in Saccharomyces cerevisiae: a novel role for ABC-cassette transporters in mediating anti-estrogenic activity.
Topics: ATP-Binding Cassette Transporters; beta-Galactosidase; Clomiphene; Cloning, Molecular; Estriol; Estrogen Antagonists; Fungal Proteins; Gene Deletion; Genes, Reporter; Humans; Membrane Proteins; Nafoxidine; Polychlorinated Biphenyls; Receptors, Estrogen; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tamoxifen | 1997 |
Triphenylethylene antiestrogens induce uterine vascular endothelial growth factor expression via their partial estrogen agonist activity.
Topics: Animals; Blotting, Northern; Clomiphene; Dose-Response Relationship, Drug; Endothelial Growth Factors; Estradiol; Estrogen Antagonists; Estrogens; Female; Lymphokines; Nafoxidine; Ovariectomy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbenes; Tamoxifen; Time Factors; Uterus; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast system.
Topics: Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Humans; Indoles; Nafoxidine; Piperidines; Polyunsaturated Alkamides; Receptors, Estrogen; Saccharomyces cerevisiae; Sulfones; Tamoxifen; Two-Hybrid System Techniques | 1999 |
Evaluation and mode of action of nonsteroidal antiestrogens.
Topics: Abortifacient Agents; Biology; Chlorotrianisene; Clomiphene; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Contraceptives, Postcoital; Diethylstilbestrol; Endocrine System; Estrogens; Ethamoxytriphetol; Evaluation Studies as Topic; Family Planning Services; Fertility Agents; Hormone Antagonists; Hormones; Membrane Proteins; Nafoxidine; Physiology; Reproductive Control Agents; Spermatogenesis-Blocking Agents; Tamoxifen | 1975 |
Multifactorial activities of nonsteroidal antiestrogens against leukemia.
Topics: Antineoplastic Agents; Cell Line, Tumor; Clomiphene; DNA; Dose-Response Relationship, Drug; Estrogen Antagonists; Flow Cytometry; Humans; Leukemia, T-Cell; Nafoxidine; Tamoxifen | 2003 |
Comparison of the antiproliferative properties of antiestrogenic drugs (nafoxidine and clomiphene) on glioma cells in vitro.
Topics: Animals; Antineoplastic Agents, Hormonal; Cell Division; Cell Line, Tumor; Cell Survival; Clomiphene; Dose-Response Relationship, Drug; Estrogen Antagonists; Glioma; Humans; Nafoxidine; Rats; Tamoxifen; Tumor Stem Cell Assay | 2004 |