Page last updated: 2024-08-22

nafenopin and pirinixic acid

nafenopin has been researched along with pirinixic acid in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.04)18.7374
1990's15 (65.22)18.2507
2000's5 (21.74)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersson, K; DePierre, JW; Eriksson, AM; Lundgren, B1
Brodhecker, CA; Eacho, PI; Lanier, TL1
Bergstrand, A; DePierre, JW; Karlsson, K; Lundgren, B1
Fahl, WE; Goel, SK; Lalwani, ND; Reddy, JK1
Butterworth, BE; Cattley, RC; Popp, JA; Richardson, KK; Smith-Oliver, T1
Fahl, WE; Lalwani, ND; Reddy, JK; Reddy, MK1
Gonzalez, FJ; McBride, OW; Sher, T; Yi, HF1
Cunninghame, ME; Evans, JG; Lake, BG; Price, RJ1
Greim, H; Leibold, E; Schwarz, LR1
Alvares, K; Capone, JP; Dadras, SS; Fan, C; Iannaccone, PM; Rachubinski, RA; Rao, MS; Reddy, JK; Subramani, S; Yeldandi, AV1
Davies, MJ; Lake, BG; Price, RJ; Rumsby, PC1
Adam, M; Boie, Y; Kennedy, BP; Rushmore, TH1
Beamand, JA; Cunninghame, ME; Lake, BG; Price, RJ1
Bojes, HK; Thurman, RG2
Anderson, NL; Eacho, P; Esquer-Blasco, R; Foxworthy, P; Richardson, F1
James, NH; Roberts, RA1
Roberts, RA1
Armstrong, MJ; Ashby, J; Galloway, SM; Johnson, TE1
Depierre, JW; Xie, Y; Yang, Q1
Berger, W; Kainzbauer, E; Parzefall, W; Schulte-Hermann, R; Teufelhofer, O; Thurman, RG1
Geoghagen, TE; Miller, KK; Prough, RA; Ripp, SL; Tamasi, V; Vila, E1
Dizhe, EB; Lapikov, IA; Mogilenko, DA; Orlov, SV; Perevozchikov, AP; Shavva, VS1

Reviews

1 review(s) available for nafenopin and pirinixic acid

ArticleYear
Non-genotoxic hepatocarcinogenesis: suppression of apoptosis by peroxisome proliferators.
    Annals of the New York Academy of Sciences, 1996, Dec-27, Volume: 804

    Topics: Animals; Anticholesteremic Agents; Apoptosis; Calcium; Cyproterone Acetate; DNA; DNA Fragmentation; Inositol Phosphates; Liver Neoplasms; Liver Neoplasms, Experimental; Nafenopin; Protein Kinase C; Pyrimidines; S Phase

1996

Other Studies

22 other study(ies) available for nafenopin and pirinixic acid

ArticleYear
Is the cytosolic catalase induced by peroxisome proliferators in mouse liver on its way to the peroxisomes?
    FEBS letters, 1992, Aug-17, Volume: 308, Issue:2

    Topics: Animals; Catalase; Clofibrate; Cytosol; Enzyme Induction; Liver; Male; Mice; Mice, Inbred C57BL; Microbodies; Nafenopin; Pyrimidines

1992
Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: comparison of WY-14,643 to clofibric acid, nafenopin and LY171883.
    Carcinogenesis, 1991, Volume: 12, Issue:9

    Topics: Acetophenones; Animals; Bromodeoxyuridine; Clofibric Acid; DNA Replication; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Nafenopin; Oxidation-Reduction; Pyrimidines; Rats; Rats, Inbred F344; Tetrazoles

1991
Effects of dietary treatment with clofibrate, nafenopin or WY-14.643 on mitochondria and DNA in mouse liver.
    Biochimica et biophysica acta, 1990, Aug-17, Volume: 1035, Issue:2

    Topics: Animals; Anticholesteremic Agents; Cell Nucleus; Clofibrate; DNA; Enzymes; Liver; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron; Mitochondria, Liver; Nafenopin; Propionates; Pyrimidines; Rats; Rats, Inbred Strains; Reference Values

1990
Lack of covalent binding of peroxisome proliferators nafenopin and Wy-14 643 to DNA in vivo and in vitro.
    Toxicology letters, 1985, Volume: 24, Issue:1

    Topics: Animals; Benzo(a)pyrene; DNA; Microbodies; Microsomes, Liver; Nafenopin; Propionates; Pyrimidines; Rats; Rats, Inbred F344; RNA

1985
Effect of peroxisome proliferator carcinogens on unscheduled DNA synthesis in rat hepatocytes determined by autoradiography.
    Cancer letters, 1986, Volume: 33, Issue:3

    Topics: Animals; Autoradiography; Carcinogens; Cell Division; Diethylhexyl Phthalate; DNA Repair; In Vitro Techniques; Liver; Male; Microbodies; Nafenopin; Pyrimidines; Rats; Rats, Inbred F344

1986
Induction of peroxisomal enzymes in livers of neonatal rats exposed to lactating mothers treated with hypolipidaemic drugs. Role of drug metabolite transfer in milk.
    The Biochemical journal, 1983, Mar-15, Volume: 210, Issue:3

    Topics: Animals; Animals, Newborn; Enzyme Induction; Female; Lactation; Liver; Microbodies; Milk; Nafenopin; Peptides; Pregnancy; Propionates; Pyrimidines; Rats; Rats, Inbred F344

1983
cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor.
    Biochemistry, 1993, Jun-01, Volume: 32, Issue:21

    Topics: Acyl-CoA Oxidase; Amino Acid Sequence; Animals; Base Sequence; Chloramphenicol O-Acetyltransferase; Chromosome Mapping; Chromosomes, Human, Pair 22; Clofibrate; Cloning, Molecular; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Gene Library; Genetic Linkage; Humans; Lod Score; Mice; Microbodies; Mixed Function Oxygenases; Molecular Sequence Data; Nafenopin; Oligodeoxyribonucleotides; Oxidoreductases; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Promoter Regions, Genetic; Pyrimidines; Rabbits; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Thymidine Kinase; Transcription Factors

1993
Comparison of the hepatic effects of nafenopin and WY-14,643 on peroxisome proliferation and cell replication in the rat and Syrian hamster.
    Environmental health perspectives, 1993, Volume: 101 Suppl 5

    Topics: Animals; Carcinogens; Cell Division; Cricetinae; DNA Replication; Fatty Acids; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Microbodies; Nafenopin; Organ Size; Oxidation-Reduction; Pyrimidines; Rats; Rats, Sprague-Dawley; Species Specificity

1993
Inhibition of intercellular communication of rat hepatocytes by nafenopin: involvement of protein kinase C.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: Animals; Cell Communication; Diethylhexyl Phthalate; Isoenzymes; Liver; Male; Nafenopin; Protein Kinase C; Pyrimidines; Rats; Rats, Wistar

1994
An upstream region of the enoyl-coenzyme A hydratase/3-hydroxyacyl-coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice.
    Cancer research, 1994, May-01, Volume: 54, Issue:9

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Clofibric Acid; Diethylhexyl Phthalate; Enoyl-CoA Hydratase; Fibric Acids; Genes, Reporter; Liver; Luciferases; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Microbodies; Nafenopin; Pyrimidines

1994
Effect of some peroxisome proliferators on transforming growth factor-beta 1 gene expression and insulin-like growth factor II/mannose-6-phosphate receptor gene expression in rat liver.
    Carcinogenesis, 1994, Volume: 15, Issue:2

    Topics: Animals; Clofenapate; Clofibric Acid; Corn Oil; Gene Expression; Liver; Male; Microbodies; Nafenopin; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 2; Transforming Growth Factor beta

1994
Enantioselective activation of the peroxisome proliferator-activated receptor.
    The Journal of biological chemistry, 1993, Mar-15, Volume: 268, Issue:8

    Topics: Acyl-CoA Oxidase; Animals; Base Sequence; Cells, Cultured; Clofibric Acid; DNA; Microbodies; Molecular Sequence Data; Nafenopin; Oxidoreductases; Propionates; Pyrimidines; Quinolines; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Regulatory Sequences, Nucleic Acid; Stereoisomerism; Transcription Factors; Transcriptional Activation

1993
Culture of precision-cut liver slices: effect of some peroxisome proliferators.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1993, Volume: 31, Issue:2

    Topics: Animals; Carnitine O-Acetyltransferase; Clofibric Acid; Culture Media; Culture Techniques; Fibric Acids; Liver; Male; Microbodies; Microscopy, Electron; Nafenopin; Oxidation-Reduction; Palmitoyl Coenzyme A; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors

1993
Peroxisome proliferators activate Kupffer cells in vivo.
    Cancer research, 1996, Jan-01, Volume: 56, Issue:1

    Topics: Animals; Carcinogens; Cells, Cultured; Kupffer Cells; Male; Microbodies; Nafenopin; Phagocytosis; Pyrimidines; Rats; Rats, Inbred F344

1996
The effects of peroxisome proliferators on protein abundances in mouse liver.
    Toxicology and applied pharmacology, 1996, Volume: 137, Issue:1

    Topics: Acetophenones; Amino Acid Sequence; Animals; Anticholesteremic Agents; Clofibric Acid; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Image Processing, Computer-Assisted; Liver; Male; Mice; Microbodies; Molecular Sequence Data; Nafenopin; Oxidation-Reduction; Proteins; Pyrimidines; Rats; Tetrazoles

1996
Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis.
    Carcinogenesis, 1996, Volume: 17, Issue:8

    Topics: Animals; Apoptosis; Blood; Clofenapate; Cricetinae; Culture Media; DNA Damage; DNA Replication; Dogs; Guinea Pigs; Homeostasis; Male; Mice; Microbodies; Nafenopin; Phenobarbital; Pyrimidines; Rats; Species Specificity; Transforming Growth Factors

1996
Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver.
    Toxicology and applied pharmacology, 1996, Volume: 140, Issue:2

    Topics: Animals; Antihypertensive Agents; Antioxidants; Caprylates; Cell Division; Hypolipidemic Agents; In Vitro Techniques; Lipid Peroxidation; Male; Microbodies; Microsomes, Liver; Nafenopin; Oxidative Phosphorylation; Perfusion; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Transcription Factors

1996
The genetic toxicity of the peroxisome proliferator class of rodent hepatocarcinogen.
    Mutation research, 2000, Mar-17, Volume: 448, Issue:2

    Topics: Animals; CHO Cells; Clofenapate; Cricetinae; Diethylhexyl Phthalate; Humans; Molecular Structure; Nafenopin; Peroxisome Proliferators; Pyrimidines

2000
Effects of peroxisome proliferators on the thymus and spleen of mice.
    Clinical and experimental immunology, 2000, Volume: 122, Issue:2

    Topics: Animals; Aspirin; Atrophy; B-Lymphocytes; Caprylates; Cell Cycle; Cell Division; Diethylhexyl Phthalate; DNA; Fluorocarbons; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Nafenopin; Peroxisome Proliferators; Pyrimidines; Spleen; T-Lymphocytes; Thymus Gland

2000
Peroxisome proliferators do not increase DNA synthesis in purified rat hepatocytes.
    Carcinogenesis, 2001, Volume: 22, Issue:3

    Topics: Animals; DNA Replication; Hepatocytes; Kupffer Cells; Nafenopin; Peroxisome Proliferators; Pyrimidines; Rats

2001
Modulation of receptor phosphorylation contributes to activation of peroxisome proliferator activated receptor alpha by dehydroepiandrosterone and other peroxisome proliferators.
    Molecular pharmacology, 2008, Volume: 73, Issue:3

    Topics: Animals; Cell Line, Tumor; Cell Survival; Cells, Cultured; Data Interpretation, Statistical; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Genes, Reporter; Hepatocytes; Luciferases; Male; Mutation; Nafenopin; Peroxisome Proliferators; Phosphorylation; Plasmids; PPAR alpha; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transfection

2008
Role of the nuclear receptors HNF4 alpha, PPAR alpha, and LXRs in the TNF alpha-mediated inhibition of human apolipoprotein A-I gene expression in HepG2 cells.
    Biochemistry, 2009, Dec-22, Volume: 48, Issue:50

    Topics: Apolipoprotein A-I; Cell Line, Tumor; Down-Regulation; Hepatocyte Nuclear Factor 4; Humans; Ligands; Liver X Receptors; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Nafenopin; NF-kappa B; Orphan Nuclear Receptors; PPAR alpha; Pyrimidines; Tumor Necrosis Factor-alpha

2009