Page last updated: 2024-08-23

nafazatrom and thromboxane b2

nafazatrom has been researched along with thromboxane b2 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buchanan, MR; Butt, RW; Turpie, AG1
Carey, F; Forder, RA1
Mehta, J; Mehta, P; Roy, L1
Bennett, A; Carroll, MA; Corrigan, CJ; Melhuish, PB; Patel, S; Stamford, IF1
Choi, K; Karmali, RA; Otter, G; Schmid, F1
Bayorh, MA; Faden, AI; Feuerstein, G; Goldstein, DS; Ramwell, PW; Stull, R; Zerbe, RL1
Fiedler, VB; Grützmann, R; Mardin, M; Perzborn, E1
Coker, SJ; Parratt, JR1
Deckmyn, H; Van Houtte, E; Vermylen, J; Verstraete, M1
Fischer, S; Struppler, M; Weber, PC1

Trials

2 trial(s) available for nafazatrom and thromboxane b2

ArticleYear
Effect of nafazatrom on platelet function and release: relationship to symptomatic episodes in patients with peripheral vascular disease.
    American heart journal, 1987, Volume: 113, Issue:5

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adult; Aged; Arterial Occlusive Diseases; beta-Thromboglobulin; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Epoprostenol; Humans; Hydroxyeicosatetraenoic Acids; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Pyrazoles; Pyrazolones; Random Allocation; Thromboxane B2

1987
Lack of efficacy of nafazatrom, a novel anti-thrombotic compound, in patients with coronary artery disease.
    American heart journal, 1985, Volume: 109, Issue:5 Pt 1

    Topics: 6-Ketoprostaglandin F1 alpha; beta-Thromboglobulin; Blood Pressure; Coronary Disease; Exercise Test; Female; Fibrinolytic Agents; Heart Rate; Humans; Male; Middle Aged; Platelet Count; Platelet Factor 4; Pyrazoles; Pyrazolones; Thromboxane B2

1985

Other Studies

8 other study(ies) available for nafazatrom and thromboxane b2

ArticleYear
Radioimmunoassay of LTB4 and 6-trans LTB4: analytical and pharmacological characterisation of immunoreactive LTB4 in ionophore stimulated human blood.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 22, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antibodies; Antibody Specificity; Calcimycin; Catechols; Chromatography, High Pressure Liquid; Cross Reactions; Dose-Response Relationship, Drug; Female; Humans; Leukotriene B4; Male; Masoprocol; Pyrazoles; Pyrazolones; Rabbits; Radioimmunoassay; Thromboxane B2; Time Factors

1986
Survival of mice with NC carcinoma is unchanged by drugs that are thought to inhibit thromboxane synthesis or increase prostacyclin formation.
    British journal of cancer, 1986, Volume: 54, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antineoplastic Agents; Female; Imidazoles; Mammary Neoplasms, Experimental; Mice; Prostaglandins E; Pyrazoles; Pyrazolones; Thromboxane B2; Thromboxane-A Synthase

1986
Eicosanoids and metastasis: experimental aspects in Lewis lung carcinoma.
    Cancer biochemistry biophysics, 1986, Volume: 9, Issue:1

    Topics: Animals; Body Weight; Carcinoma; Imidazoles; Lung; Lung Neoplasms; Mice; Neoplasm Metastasis; Organ Size; Prostaglandins; Prostaglandins E; Prostaglandins F; Pyrazoles; Pyrazolones; Thromboxane B2

1986
Effects of nafazatrom on cardiovascular, sympathetic, and endocrine responses to hemorrhagic shock in conscious rats.
    Circulatory shock, 1985, Volume: 17, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine Vasopressin; Blood Pressure; Epinephrine; Fibrinolytic Agents; Heart Rate; Male; Norepinephrine; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Strains; Shock, Hemorrhagic; SRS-A; Thromboxane B2

1985
The effects of nafazatrom in an acute occlusion-reperfusion model of canine myocardial injury.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:2-3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Coronary Circulation; Disease Models, Animal; Dogs; Electrocardiography; Female; Male; Myocardial Infarction; Perfusion; Platelet Aggregation; Pyrazoles; Pyrazolones; Thromboxane B2

1985
The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds.
    Journal of molecular and cellular cardiology, 1984, Volume: 16, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia; Animals; Arrhythmias, Cardiac; Coronary Disease; Dogs; Epoprostenol; Female; Fibrinolytic Agents; Male; Perfusion; Prostaglandins; Pyrazoles; Pyrazolones; Thromboxane B2

1984
Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom.
    Biochemical pharmacology, 1983, Sep-15, Volume: 32, Issue:18

    Topics: Animals; Aspirin; Dinoprost; Drug Interactions; Fibrinolytic Agents; Functional Laterality; Imidazoles; Kinetics; Male; Prostaglandins F; Pyrazoles; Pyrazolones; Rabbits; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
In vivo and in vitro effects of nafazatrom (Bay g 6575), an antithrombotic compound, on arachidonic acid metabolism in platelets and vascular tissue.
    Biochemical pharmacology, 1983, Jul-15, Volume: 32, Issue:14

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acids; Blood Platelets; Blood Vessels; Fibrinolytic Agents; Humans; Kidney Cortex; Male; Microsomes; Middle Aged; Platelet Aggregation; Platelet Count; Pyrazoles; Pyrazolones; Thromboxane B2

1983