nafamostat and gemcitabine

nafamostat has been researched along with gemcitabine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's7 (58.33)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Gocho, T; Hirohara, S; Ito, R; Misawa, T; Sadaoka, S; Sakamoto, T; Shiba, H; Uwagawa, T; Wakiyama, S; Yanaga, K1
Chiao, PJ; Gocho, T; Hirohara, S; Misawa, T; Uwagawa, T; Yanaga, K1
Gocho, T; Hirohara, S; Ito, R; Misawa, T; Sadaoka, S; Tsutsui, N; Uwagawa, T; Yanaga, K1
Fujiwara, Y; Furukawa, K; Gocho, T; Haruki, K; Iwase, R; Misawa, T; Shiba, H; Uwagawa, T; Yanaga, K1
Fujiwara, Y; Furukawa, K; Haruki, K; Iwase, R; Misawa, T; Ohashi, T; Shiba, H; Uwagawa, T; Yanaga, K2
Uwagawa, T; Yanaga, K1
Fujiwara, Y; Futagawa, Y; Misawa, T; Shiba, H; Uwagawa, T; Yanaga, K1
Haruki, K; Horiuchi, T; Iwase, R; Ohashi, T; Saito, N; Shiba, H; Shirai, Y; Uwagawa, T; Yanaga, K1
Furukawa, K; Gocho, T; Onda, S; Sakamoto, T; Shiba, H; Shiozaki, H; Uwagawa, T; Yanaga, K; Yasuda, J1
Furukawa, K; Gocho, T; Hamura, R; Ikegami, T; Onda, S; Sakamoto, T; Shiba, H; Shirai, Y; Uwagawa, T; Yanaga, K; Yasuda, J1

Reviews

1 review(s) available for nafamostat and gemcitabine

ArticleYear
Effect of NF-κB inhibition on chemoresistance in biliary-pancreatic cancer.
    Surgery today, 2015, Volume: 45, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamidines; Biliary Tract Neoplasms; Bortezomib; Camptothecin; Curcumin; Deoxycytidine; Ditiocarb; Drug Resistance, Neoplasm; Gemcitabine; Guanidines; Humans; Irinotecan; Molecular Targeted Therapy; NF-kappa B; Paclitaxel; Pancreatic Neoplasms; Pregnenediones; Treatment Outcome

2015

Trials

5 trial(s) available for nafamostat and gemcitabine

ArticleYear
A phase I study of full-dose gemcitabine and regional arterial infusion of nafamostat mesilate for advanced pancreatic cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzamidines; Biomarkers, Tumor; CA-19-9 Antigen; Deoxycytidine; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Gemcitabine; Guanidines; Humans; Infusions, Intra-Arterial; Male; Maximum Tolerated Dose; Middle Aged; Molecular Structure; Pancreatic Neoplasms; Remission Induction; Survival Analysis; Time Factors; Treatment Outcome

2009
Phase II study of gemcitabine in combination with regional arterial infusion of nafamostat mesilate for advanced pancreatic cancer.
    American journal of clinical oncology, 2013, Volume: 36, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamidines; Deoxycytidine; Female; Gemcitabine; Guanidines; Humans; Infusions, Intra-Arterial; Kaplan-Meier Estimate; Male; Middle Aged; Pancreatic Neoplasms; Treatment Outcome

2013
Prognostic factors of unresectable pancreatic cancer treated with nafamostat mesilate combined with gemcitabine chemotherapy.
    Anticancer research, 2012, Volume: 32, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamidines; Deoxycytidine; Female; Gemcitabine; Guanidines; Humans; Male; Middle Aged; Pancreatic Neoplasms; Prognosis; Survival Analysis

2012
Phase II Study of Adjuvant Chemotherapy With Gemcitabine and Nafamostat Mesilate for Pancreatic Cancer.
    Pancreas, 2021, 03-01, Volume: 50, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamidines; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Exanthema; Female; Gemcitabine; Guanidines; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neutropenia; Pancreatic Neoplasms; Postoperative Period; Treatment Outcome

2021
Phase II trial of nafamostat mesilate/gemcitabin/S-1 for unresectable pancreatic cancer.
    PloS one, 2022, Volume: 17, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamidines; Deoxycytidine; Female; Gemcitabine; Guanidines; Humans; Male; Pancreatic Neoplasms; Treatment Outcome

2022

Other Studies

6 other study(ies) available for nafamostat and gemcitabine

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Combination chemotherapy of nafamostat mesilate with gemcitabine for pancreatic cancer targeting NF-kappaB activation.
    Anticancer research, 2009, Volume: 29, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Benzamidines; Cell Cycle; Deoxycytidine; Drug Therapy, Combination; Electrophoretic Mobility Shift Assay; Gemcitabine; Guanidines; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Nude; NF-kappa B; Pancreatic Neoplasms; Ribonucleotide Reductases; Serine Proteinase Inhibitors; Tumor Cells, Cultured

2009
Inhibition of nuclear factor kappa-B enhances the antitumor effect of combination treatment with tumor necrosis factor-alpha gene therapy and gemcitabine for pancreatic cancer in mice.
    Journal of the American College of Surgeons, 2013, Volume: 216, Issue:2

    Topics: Adenoviridae; Analysis of Variance; Animals; Benzamidines; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Deoxycytidine; Enzyme-Linked Immunosorbent Assay; Gemcitabine; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Guanidines; Humans; In Situ Nick-End Labeling; Mice; Mice, Nude; NF-kappa B; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays

2013
Combination chemotherapy of nafamostat mesylate with gemcitabine for gallbladder cancer targeting nuclear factor-κB activation.
    The Journal of surgical research, 2013, Volume: 184, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Benzamidines; Carcinoma; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Gallbladder Neoplasms; Gemcitabine; Guanidines; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Serine Proteinase Inhibitors; Xenograft Model Antitumor Assays

2013
Radical Resection of a Primarily Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy Using Gemcitabine, TS-1, and Nafamostat Mesilate; Report of a Case.
    International surgery, 2015, Volume: 100, Issue:2

    Topics: Antimetabolites, Antineoplastic; Benzamidines; Deoxycytidine; Gemcitabine; Guanidines; Humans; Male; Middle Aged; Neoadjuvant Therapy; Pancreatic Neoplasms; Pancreaticoduodenectomy; Silicates; Titanium; Tomography, X-Ray Computed

2015
New treatment strategy with nuclear factor-κB inhibitor for pancreatic cancer.
    The Journal of surgical research, 2016, Volume: 206, Issue:1

    Topics: Albumins; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamidines; Biomarkers; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Drug Administration Schedule; Gemcitabine; Guanidines; Humans; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Paclitaxel; Pancreatic Neoplasms; Xenograft Model Antitumor Assays

2016