nafamostat has been researched along with camostat in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.70) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 19 (70.37) | 2.80 |
| Authors | Studies |
|---|---|
| Franco, FM; Han, Z; Harris, PK; Janetka, JW; Jarvis, CM; Jones, DE; Wildman, SA | 1 |
| Birchall, K; Chapman, TM; Desai, B; Klefström, J; Mukonoweshuro, A; Pant, SM; Ramjee, MK; Selway, CN; Tarver, GJ; Tervonen, TA; Wright, AG | 1 |
| Agard, DA; Ashworth, A; Barrio-Hernandez, I; Batra, J; Beltrao, P; Bennett, MJ; Bohn, M; Bouhaddou, M; Braberg, H; Broadhurst, DJ; Cai, Y; Cakir, M; Calviello, L; Cavero, DA; Chang, JCJ; Chorba, JS; Craik, CS; d'Enfert, C; Dai, SA; Eckhardt, M; Emerman, M; Fabius, JM; Fletcher, SJ; Floor, SN; Foussard, H; Frankel, AD; Fraser, JS; Fujimori, DG; Ganesan, SJ; García-Sastre, A; Gordon, DE; Gross, JD; Guo, JZ; Haas, K; Haas, P; Hernandez-Armenta, C; Hiatt, J; Huang, XP; Hubert, M; Hüttenhain, R; Ideker, T; Jacobson, M; Jang, GM; Jura, N; Kaake, RM; Kim, M; Kirby, IT; Klippsten, S; Koh, C; Kortemme, T; Krogan, NJ; Kuzuoglu-Ozturk, D; Li, Q; Liboy-Lugo, J; Lin, Y; Liu, X; Liu, Y; Lou, K; Lyu, J; Mac Kain, A; Malik, HS; Mathy, CJP; McGregor, MJ; Melnyk, JE; Memon, D; Meyer, B; Miorin, L; Modak, M; Moreno, E; Mukherjee, S; Naing, ZZC; Noack, J; O'Meara, MJ; O'Neal, MC; Obernier, K; Ott, M; Peng, S; Perica, T; Pilla, KB; Polacco, BJ; Rakesh, R; Rathore, U; Rezelj, VV; Richards, AL; Roesch, F; Rosenberg, OS; Rosenthal, SB; Roth, BL; Roth, TL; Ruggero, D; Safari, M; Sali, A; Saltzberg, DJ; Savar, NS; Schwartz, O; Sharp, PP; Shen, W; Shengjuler, D; Shi, Y; Shoichet, BK; Shokat, KM; Soucheray, M; Stroud, RM; Subramanian, A; Swaney, DL; Taunton, J; Tran, QD; Trenker, R; Tummino, TA; Tutuncuoglu, B; Ugur, FS; Vallet, T; Venkataramanan, S; Verba, KA; Verdin, E; Vignuzzi, M; von Zastrow, M; Wang, HY; Wankowicz, SA; Wenzell, NA; White, KM; Xu, J; Young, JM; Zhang, Z; Zhou, Y | 1 |
| Chen, J; Chen, W; Choudhry, N; Xu, D; Yang, Z; Zanin, M; Zhao, X | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Chiba, S; Horiuchi, A; Iwatsuki, K; Ren, LM; Yonekura, H | 1 |
| Takeuchi, T; Toki, F; Yoshida, K | 1 |
| Fuchinoue, S; Honda, H; Kawai, T; Sanaka, T; Takahashi, K; Tanabe, K; Teraoka, S; Toma, H; Yagisawa, T; Yamaguchi, Y | 1 |
| De Clercq, E; Hosoya, M; Ishii, T; Shigeta, S; Suzuki, H | 1 |
| Noda, Y; Yin, J; Yotsuyanagi, T | 1 |
| Hide, M; Kameyoshi, Y; Shindo, H; Takahagi, S; Watanabe, M | 1 |
| Fang, Y; Meng, XM; Ni, WJ; Shen, AZ; Xu, T; Zhou, H | 1 |
| Deng, X; Kikuchi, A; Nagatomi, R; Nishimura, H; Yamaya, M | 1 |
| Gohda, J; Imai, M; Inoue, JI; Iwatsuki-Horimoto, K; Kawaguchi, Y; Kawaoka, Y; Kinoshita, N; Kiso, M; Matsuda, Z; Ohmagari, N; Sakai-Tagawa, Y; Semba, K; Takeda, M; Yamamoto, M | 1 |
| Fätkenheuer, G; Malin, JJ; Rybniker, J; Simonis, A; Theobald, SJ | 1 |
| Al-Rejaie, S; ElMasry, G; Kishk, RM; Kishk, SM; Nafie, MS; Nemr, NA; Simons, C; Yassen, ASA | 1 |
| Chinnasamy, K; Iruthayaraj, A; Kandasamy, S; Magudeeswaran, S; Poomani, K; Ramakrishnan, J | 1 |
| Bojkova, D; Ciesek, S; Cinatl, J; Claussen, C; Ellinger, B; Geisslinger, G; Gribbon, P; Keminer, O; Kuzikov, M; Reinshagen, J; Westhaus, S; Wolf, M; Zaliani, A | 1 |
| Huang, X; Omenn, GS; Pearce, R; Zhang, Y | 1 |
| Bartlett, JA; Li, K; McCray, PB; Meyerholz, DK | 1 |
| Balistreri, G; Kirchhausen, T; Kreutzberger, AJB; Ojha, R; Pyle, JD; Sanyal, A; Vapalahti, O | 1 |
| Hayashi, H; Hongo, S; Kawakami, K; Matsuzaki, Y; Nishimura, H; Sato, K; Shimotai, Y; Yamaya, M | 1 |
| Azouz, NP; Chung, DH; Craik, CS; Damalanka, VC; Hoffmann, M; Janetka, JW; Karmakar, P; Klampfer, L; Klingler, AM; Lee, M; Lourenço, AL; Mahoney, M; Mayer Bridwell, AE; O'Donoghue, AJ; Pöhlmann, S; Pwee, D; Rothenberg, ME; Rothlauf, PW; Stallings, CL; Tartell, MA; Thompson, CE; Voss, J; Whelan, SPJ | 1 |
| Barygin, OI; Zhigulin, AS | 1 |
| Barygin, OI; Tikhonov, DB; Zhigulin, AS | 1 |
| C, AM; Ponnuraj, K; Wessler, S | 1 |
| Fujimoto, KJ; Kondo, A; Yanai, T | 1 |
3 review(s) available for nafamostat and camostat
| Article | Year |
|---|---|
Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Topics: Antiviral Agents; China; Coronavirus Protease Inhibitors; COVID-19; COVID-19 Drug Treatment; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; SARS-CoV-2; Small Molecule Libraries | 2020 |
Potential therapeutic targets and promising drugs for combating SARS-CoV-2.
Topics: Adenosine Monophosphate; Alanine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Basigin; Benzamidines; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; COVID-19 Vaccines; Cytokine Release Syndrome; Esters; Gabexate; Genome, Viral; Guanidines; Humans; Immunization, Passive; Immunosuppressive Agents; Medicine, Chinese Traditional; Nucleic Acid Synthesis Inhibitors; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Protease Inhibitors; RNA-Dependent RNA Polymerase; SARS-CoV-2; Serine Endopeptidases; Spike Glycoprotein, Coronavirus; Viral Vaccines; Virus Internalization; Virus Replication | 2020 |
A comparative analysis of remdesivir and other repurposed antivirals against SARS-CoV-2.
Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Benzamidines; COVID-19 Drug Treatment; Drug Repositioning; Esters; Guanidines; Guanine; Humans; Indoles; Lopinavir; Protease Inhibitors; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Virus Internalization; Virus Replication | 2021 |
24 other study(ies) available for nafamostat and camostat
| Article | Year |
|---|---|
Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.
Topics: Amidines; Antineoplastic Agents; Arginine; Benzamidines; Catalytic Domain; Drug Design; Enzyme Assays; Guanidines; High-Throughput Screening Assays; Humans; Kinetics; Molecular Docking Simulation; Neoplasm Proteins; Peptidomimetics; Phenylalanine; Piperazines; Protease Inhibitors; Recombinant Proteins; Serine Endopeptidases; Structure-Activity Relationship; Urea | 2015 |
Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform.
Topics: Breast Neoplasms; Cell Proliferation; Drug Design; Enzyme Inhibitors; Female; High-Throughput Screening Assays; Humans; Models, Molecular; Molecular Structure; Protein Conformation; Serine Endopeptidases; Tumor Cells, Cultured | 2018 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Topics: Animals; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Cloning, Molecular; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; HEK293 Cells; Host-Pathogen Interactions; Humans; Immunity, Innate; Mass Spectrometry; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; Protein Binding; Protein Biosynthesis; Protein Domains; Protein Interaction Mapping; Protein Interaction Maps; Receptors, sigma; SARS-CoV-2; SKP Cullin F-Box Protein Ligases; Vero Cells; Viral Proteins | 2020 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Gabexate and camostat, synthetic proteinase inhibitors, as direct inducing factors of water and bicarbonate secretion in the isolated and blood-perfused dog pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aprotinin; Benzamidines; Bicarbonates; Body Water; Cyclic AMP; Dogs; Esters; Female; Gabexate; Glycoproteins; Guanidines; In Vitro Techniques; Male; Pancreas; Perfusion; Protease Inhibitors; Secretin | 1990 |
[Antienzyme preparations in the treatment of acute pancreatitis].
Topics: Acute Disease; Adult; Aprotinin; Benzamidines; Cytidine Diphosphate Choline; Disseminated Intravascular Coagulation; Esters; Gabexate; Glycoproteins; Guanidines; Humans; Male; Multiple Organ Failure; Pancreatitis; Serine Proteinase Inhibitors; Trypsin Inhibitors | 1990 |
New approach to management of chronic vascular rejection with prostacyclin analogue after kidney transplantation.
Topics: alpha-Cyclodextrins; Benzamidines; Blood Platelets; Cyclodextrins; Epoprostenol; Esters; Gabexate; Graft Rejection; Guanidines; Humans; Kidney; Kidney Transplantation; Vascular Diseases | 1987 |
Comparative inhibitory effects of various nucleoside and nonnucleoside analogues on replication of influenza virus types A and B in vitro and in ovo.
Topics: Adenosine; Animals; Antiviral Agents; Benzamidines; Cells, Cultured; Chick Embryo; Dextran Sulfate; Dose-Response Relationship, Drug; Esters; Gabexate; Guanidines; Guanosine; Influenza A virus; Influenza B virus; Nucleosides; Protease Inhibitors; Ribavirin; Virus Replication | 1993 |
Properties of poly(lactic-co-glycolic acid) nanospheres containing protease inhibitors: camostat mesilate and nafamostat mesilate.
Topics: Benzamidines; Chemistry, Pharmaceutical; Esters; Gabexate; Guanidines; Lactic Acid; Molecular Weight; Nanotubes; Particle Size; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Protease Inhibitors; Solubility | 2006 |
Refractory chronic urticaria treated effectively with the protease inhibitors, nafamostat mesilate and camostat mesilate.
Topics: Adult; Benzamidines; Chronic Disease; Drug Therapy, Combination; Esters; Female; Gabexate; Guanidines; Humans; Male; Middle Aged; Protease Inhibitors; Treatment Outcome; Urticaria | 2010 |
Protease Inhibitors: Candidate Drugs to Inhibit Severe Acute Respiratory Syndrome Coronavirus 2 Replication.
Topics: Antiviral Agents; Benzamidines; Betacoronavirus; Cells, Cultured; Coronavirus 229E, Human; Coronavirus Infections; COVID-19; Culture Media, Conditioned; Epithelial Cells; Esters; Gabexate; Guanidines; Humans; Nasal Mucosa; Pandemics; Pneumonia, Viral; Primary Cell Culture; Protease Inhibitors; SARS-CoV-2; Serine Endopeptidases; Spike Glycoprotein, Coronavirus; Viral Load; Virus Replication | 2020 |
The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner.
Topics: Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticoagulants; Benzamidines; Betacoronavirus; Cell Line; Chlorocebus aethiops; Coronavirus Infections; COVID-19; Esters; Gabexate; Guanidines; HEK293 Cells; Humans; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; SARS-CoV-2; Serine Endopeptidases; Spike Glycoprotein, Coronavirus; Vero Cells; Virus Internalization | 2020 |
Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies.
Topics: Antiviral Agents; Benzamidines; Betacoronavirus; Coronavirus Infections; COVID-19; Esters; Gabexate; Glycine; Guanidines; Humans; Ligands; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Pandemics; Pneumonia, Viral; Protein Structure, Tertiary; SARS-CoV-2; Sequence Homology, Amino Acid; Serine Endopeptidases; Serine Proteinase Inhibitors; Sulfonamides | 2020 |
Strong Binding of Leupeptin with TMPRSS2 Protease May Be an Alternative to Camostat and Nafamostat for SARS-CoV-2 Repurposed Drug: Evaluation from Molecular Docking and Molecular Dynamics Simulations.
Topics: Antiviral Agents; Benzamidines; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Esters; Guanidines; Humans; Leupeptins; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; SARS-CoV-2; Serine Endopeptidases | 2021 |
A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection.
Topics: Antiviral Agents; Benzamidines; Caco-2 Cells; Cetylpyridinium; COVID-19; Drug Evaluation, Preclinical; Drug Repositioning; Esters; Guanidines; Humans; Lopinavir; Mefloquine; Papaverine; SARS-CoV-2 | 2021 |
Identification of 13 Guanidinobenzoyl- or Aminidinobenzoyl-Containing Drugs to Potentially Inhibit TMPRSS2 for COVID-19 Treatment.
Topics: Antiviral Agents; Benzamidines; Binding Sites; Catalytic Domain; COVID-19; COVID-19 Drug Treatment; Esters; Guanidines; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Serine Endopeptidases; Serine Proteinase Inhibitors; Thermodynamics | 2021 |
The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19.
Topics: Angiotensin-Converting Enzyme 2; Animals; Benzamidines; Cells, Cultured; COVID-19 Drug Treatment; Disease Models, Animal; Drug Evaluation, Preclinical; Esters; Guanidines; Humans; Lung; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle East Respiratory Syndrome Coronavirus; Respiratory Mucosa; SARS-CoV-2; Serine Endopeptidases; Serine Proteinase Inhibitors; Spike Glycoprotein, Coronavirus; Virus Internalization | 2021 |
Synergistic Block of SARS-CoV-2 Infection by Combined Drug Inhibition of the Host Entry Factors PIKfyve Kinase and TMPRSS2 Protease.
Topics: Animals; Antiviral Agents; Benzamidines; Cell Line, Tumor; Chlorocebus aethiops; COVID-19 Drug Treatment; Drug Synergism; Esters; Guanidines; Humans; Hydrazones; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protease Inhibitors; Pyrimidines; SARS-CoV-2; Serine Endopeptidases; Vero Cells; Virus Internalization | 2021 |
TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus.
Topics: Amino Acid Sequence; Animals; Antiviral Agents; Benzamidines; Cell Line; Cell Line, Tumor; Cells, Cultured; Dogs; Esters; Gammainfluenzavirus; Guanidines; Hemagglutinins, Viral; Host Microbial Interactions; Humans; Influenza, Human; Madin Darby Canine Kidney Cells; Orthomyxoviridae Infections; Serine Endopeptidases; Trypsin; Viral Fusion Proteins; Viral Proteins | 2021 |
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
Topics: Animals; Benzamidines; Benzothiazoles; Cell Line; COVID-19; COVID-19 Drug Treatment; Drug Design; Epithelial Cells; Esters; Guanidines; Humans; Lung; Mice; Middle East Respiratory Syndrome Coronavirus; Oligopeptides; SARS-CoV-2; Serine Endopeptidases; Small Molecule Libraries; Substrate Specificity; Virus Internalization | 2021 |
Mechanisms of NMDA receptor inhibition by nafamostat, gabexate and furamidine.
Topics: Animals; Benzamidines; Drug Repositioning; Esters; Gabexate; Guanidines; Hippocampus; Inhibitory Concentration 50; Male; Models, Animal; Neurodegenerative Diseases; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine Proteinase Inhibitors | 2022 |
Mechanisms of acid-sensing ion channels inhibition by nafamostat, sepimostat and diminazene.
Topics: Acid Sensing Ion Channels; Animals; Diminazene; Gabexate; Guanidines; Hydrogen-Ion Concentration; Rats | 2023 |
Inhibition of Listeria Monocytogenes HtrA Protease with Camostat, Gabexate and Nafamostat Mesylates and the Binding Mode of the Inhibitors.
Topics: COVID-19; Gabexate; Humans; Listeria monocytogenes; Mesylates; Peptide Hydrolases; Protease Inhibitors; RNA, Viral; SARS-CoV-2 | 2023 |
A quantum chemical study on the anti-SARS-CoV-2 activity of TMPRSS2 inhibitors.
Topics: COVID-19; Guanidines; Humans; SARS-CoV-2; Serine Endopeptidases | 2023 |