nafagrel has been researched along with thromboxane b2 in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 15 (93.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, Y; Ashida, S; Irie, K; Kunitada, S; Masumura, H | 2 |
| Echizen, H; Fujiwara, H; Ishizaki, T; Ohnishi, A; Tanaka, T; Yasuda, K | 1 |
| Matsumoto, K; Ono, S; Takami, M; Takata, Y; Tsukada, W | 1 |
| Hakusui, H; Nii, S; Ono, K; Shibata, H; Shiozawa, T; Suzuki, T; Takegoshi, T; Tanaka, M | 1 |
| Inoue, H; Kawakubo, K; Murakawa, Y; Nozaki, A; Sugimoto, T; Toda, I; Yoshimoto, N | 1 |
| Hakusui, H; Nii, S; Ono, K; Shibata, H; Shiozawa, T; Takegoshi, T; Tanaka, M | 1 |
| Nii, S; Ono, K; Shibata, H; Shiozawa, T; Suzuki, T; Takegoshi, T; Tanaka, M | 1 |
| Ito, M; Nagamatsu, T; Nagao, T; Suzuki, Y | 1 |
| Homma, M; Ichikawa, Y; Tojo, T; Yoshida, T | 1 |
| Asai, S; Fukushima, C; Hara, K; Kohno, S; Matsuse, H; Sakai, H; Shimoda, T; Takao, A | 1 |
| Nagamatsu, T; Nagao, T; Suzuki, Y | 1 |
| Homma, M; Ikeda, Y; Kameda, H; Masashi, A; Yoshida, T | 1 |
| Takami, M; Tsukada, W | 3 |
1 trial(s) available for nafagrel and thromboxane b2
| Article | Year |
|---|---|
Improvement of renal function with selective thromboxane A2 synthetase inhibitor, DP-1904 in lupus nephritis.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Cross-Over Studies; Enzyme Inhibitors; Female; Humans; Imidazoles; Indomethacin; Lupus Nephritis; Male; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1997 |
15 other study(ies) available for nafagrel and thromboxane b2
| Article | Year |
|---|---|
A thromboxane A2 synthetase inhibitor retards hypertensive rat diabetic nephropathy.
Topics: Acetylglucosaminidase; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; gamma-Glutamyltransferase; Heart Rate; Hypertension; Imidazoles; Kidney; Prostaglandins; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1992 |
Effects of a sustained thromboxane synthase inhibition on exercise-induced changes in eicosanoid formation, catecholamine concentration, and platelet aggregation in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Chromatography, High Pressure Liquid; Epinephrine; Humans; Imidazoles; Male; Norepinephrine; Physical Exertion; Platelet Aggregation; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1992 |
Effect of DP-1904, a new thromboxane A2 synthetase inhibitor, on guinea pig experimental asthma.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antigens; Asthma; Bronchoconstriction; Guinea Pigs; Imidazoles; In Vitro Techniques; Lung; Ovalbumin; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1991 |
The pharmacokinetics and pharmacodynamics of a new thromboxane synthetase inhibitor, 6-(1-imidazolylmethyl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (DP-1904) in man after repeated oral doses.
Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Half-Life; Humans; Imidazoles; Male; Metabolic Clearance Rate; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1990 |
A thromboxane A2 synthase inhibitor, DP-1904, prevents rat renal injury.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Hydronephrosis; Imidazoles; Ischemia; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1991 |
Effects of a thromboxane A2 synthetase inhibitor on ventricular fibrillation threshold during coronary artery occlusion and reperfusion.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Coronary Disease; Coronary Vessels; Dogs; Electrophysiology; Female; Heart Rate; Heart Ventricles; Imidazoles; Ligation; Male; Naphthalenes; Refractory Period, Electrophysiological; Reperfusion; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase; Ventricular Fibrillation | 1990 |
Disposition and effect of the new thromboxane synthetase inhibitor 6-(1-imidazolylmethyl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid in man.
Topics: Adult; Feces; Half-Life; Humans; Imidazoles; Male; Naphthalenes; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1990 |
The pharmacokinetics and pharmacodynamics of a new thromboxane synthetase inhibitor, 6-(1-imidazolylmethyl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (DP-1904), in man after single oral administration.
Topics: Administration, Oral; Adult; Humans; Imidazoles; Male; Middle Aged; Naphthalenes; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1989 |
Effect of DP-1904, a thromboxane A2 synthetase inhibitor, on crescentic nephritis in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Basement Membrane; Cholesterol; Dinoprostone; Fluorescent Antibody Technique; Imidazoles; Kidney Glomerulus; Male; Methacrylates; Nephritis, Interstitial; Platelet Aggregation; Proteinuria; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1994 |
Abnormal prostanoid metabolism in lupus nephritis and the effects of a thromboxane A2 synthetase inhibitor, DP-1904.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Enzyme Inhibitors; Female; Humans; Imidazoles; Kidney Diseases; Lupus Erythematosus, Systemic; Lupus Nephritis; Male; Middle Aged; Prostaglandins; Reference Values; Regression Analysis; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1996 |
Inhibitory effect of thromboxane A2 synthetase inhibitor, DP-1904, on antigen-induced contraction of human lung parenchyma.
Topics: Aged; Animals; Antigens; Bronchoconstriction; Dose-Response Relationship, Immunologic; Enzyme Inhibitors; Female; Humans; Imidazoles; Leukotrienes; Lung; Male; Middle Aged; Mites; Muscle Contraction; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1996 |
Effect of DP-1904, a thromboxane A2 synthase inhibitor, on passive Heymann nephritis in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antibodies; Azathioprine; Creatinine; Dinoprostone; Drug Interactions; Enzyme Inhibitors; Glomerulonephritis; Imidazoles; Immunoglobulin G; Immunosuppressive Agents; Kidney Glomerulus; Male; Methacrylates; Proteinuria; Rabbits; Rats; Rats, Sprague-Dawley; Renal Circulation; Tetrahydronaphthalenes; Thromboxane B2; Thromboxane-A Synthase | 1996 |
Correlative alteration of thromboxane A2 with antigen-induced bronchoconstriction and the role of platelets as a source of TXA2 synthesis in guinea pigs: effect of DP-1904, an inhibitor of thromboxane synthetase.
Topics: Animals; Anti-Asthmatic Agents; Antigens; Asthma; Blood Platelets; Enzyme Inhibitors; Guinea Pigs; Imidazoles; Male; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1998 |
In vitro effect of DP-1904, a novel anti-asthma agent, against antigen-induced constriction and TXB2 release from the isolated guinea-pig lung parenchymal tissue.
Topics: Animals; Anti-Asthmatic Agents; Antigens; Benzoquinones; Bronchoconstriction; Chromones; Enzyme Inhibitors; Guinea Pigs; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Lung; Male; Pyrilamine; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1998 |
Effects of DP-1904, a thromboxane synthetase inhibitor, on the antigen-induced airway hyperresponsiveness and infiltration of inflammatory cells in guinea-pigs.
Topics: Acetylcholine; Animals; Bronchoalveolar Lavage; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Imidazoles; Lymphocytes; Male; Respiratory Hypersensitivity; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Time Factors | 1998 |