nafagrel has been researched along with thromboxane a2 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 10 (76.92) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iimura, O; Iwamoto, T; Miura, T; Ogawa, T; Shimamoto, K; Tsuchida, A | 1 |
| Abe, Y; Ashida, S; Irie, K; Kunitada, S; Masumura, H | 1 |
| Iwanaga, T; Kitamura, S; Kobayashi, J; Kuratomi, Y; Shimizu, K | 1 |
| Furuhama, K; Matsumoto, K; Takami, M; Takata, Y; Tsukada, W | 1 |
| Hidaka, T; Ishizuka, T; Kawaguchi, Y; Kawakami, M; Matsuki, Y; Nakamura, H; Suzuki, K | 1 |
| Homma, M; Ichikawa, Y; Kameda, H; Tojo, T; Yoshida, T | 1 |
| Abe, K; Funakoshi, M; Horiguchi, S; Karibe, A; Katoh, H; Keitoku, M; Kohzuki, M; Nose, M; Okayama, H; Satoh, S; Shirato, K; Suzuki, S; Takeuchi, M; Watanabe, J | 1 |
| Takami, M; Tsukada, W | 4 |
| Koseki, J; Nagamatsu, T; Nagao, T; Suzuki, Y | 1 |
| Hirata, D; Iwamoto, M; Kaneko, N; Masuyama, J; Minota, S; Nara, H; Okazaki, H; Yoshio, T | 1 |
1 trial(s) available for nafagrel and thromboxane a2
| Article | Year |
|---|---|
Improvement of renal function with a selective thromboxane A2 synthetase inhibitor, DP-1904, in lupus nephritis.
Topics: Adult; Enzyme Inhibitors; Female; Humans; Imidazoles; Indomethacin; Kidney; Lupus Nephritis; Middle Aged; Prostaglandins; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane-A Synthase | 1996 |
12 other study(ies) available for nafagrel and thromboxane a2
| Article | Year |
|---|---|
Inhibition of thromboxane A2 synthetase failed to limit myocardial infarct size in a rabbit ischemia-reperfusion model.
Topics: Animals; Constriction; Coronary Vessels; Disease Models, Animal; Heparin; Imidazoles; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Necrosis; Rabbits; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane-A Synthase | 1991 |
A thromboxane A2 synthase inhibitor, DP-1904, prevents rat renal injury.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Hydronephrosis; Imidazoles; Ischemia; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1991 |
[Effects of thromboxane A2 synthetase inhibitor, DP-1904 on the action of vasoactive substances in rabbit blood vessel smooth muscle preparations].
Topics: Animals; Aorta, Thoracic; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Pulmonary Artery; Rabbits; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane-A Synthase; Vasoconstrictor Agents | 1989 |
Possible role of thromboxane A2 in hyperresponsiveness of isolated rat lung tissue in a Sephadex-induced eosinophilia model.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Atropine; Bronchial Hyperreactivity; Dextrans; Dose-Response Relationship, Drug; Imidazoles; Leukotriene D4; Lung; Male; Methysergide; Prostaglandin Endoperoxides, Synthetic; Pulmonary Eosinophilia; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thromboxane A2; Vasoconstrictor Agents | 1995 |
DP-1904, a specific inhibitor of thromboxane A2 synthesizing enzyme, suppresses ICAM-1 expression by stimulated vascular endothelial cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Cell Division; Cells, Cultured; Cycloheximide; Endothelium, Vascular; Epoprostenol; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-1; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Recombinant Proteins; Tetrahydronaphthalenes; Thrombin; Thromboxane A2; Thromboxane-A Synthase; Tumor Necrosis Factor-alpha; Umbilical Veins | 1994 |
FMLP actions and its binding sites in isolated human coronary arteries.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Coronary Vessels; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Imidazoles; Indomethacin; Intramolecular Oxidoreductases; Isomerases; Isometric Contraction; Macrophages; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Prostaglandins; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; RNA, Messenger; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane-A Synthase | 1997 |
Correlative alteration of thromboxane A2 with antigen-induced bronchoconstriction and the role of platelets as a source of TXA2 synthesis in guinea pigs: effect of DP-1904, an inhibitor of thromboxane synthetase.
Topics: Animals; Anti-Asthmatic Agents; Antigens; Asthma; Blood Platelets; Enzyme Inhibitors; Guinea Pigs; Imidazoles; Male; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1998 |
In vitro effect of DP-1904, a novel anti-asthma agent, against antigen-induced constriction and TXB2 release from the isolated guinea-pig lung parenchymal tissue.
Topics: Animals; Anti-Asthmatic Agents; Antigens; Benzoquinones; Bronchoconstriction; Chromones; Enzyme Inhibitors; Guinea Pigs; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Lung; Male; Pyrilamine; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1998 |
Effects of DP-1904, a thromboxane synthetase inhibitor, on the antigen-induced airway hyperresponsiveness and infiltration of inflammatory cells in guinea-pigs.
Topics: Acetylcholine; Animals; Bronchoalveolar Lavage; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Imidazoles; Lymphocytes; Male; Respiratory Hypersensitivity; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Time Factors | 1998 |
A possible involvement of thromboxane A2 and peptide leukotrienes in hyperresponsiveness of Sephadex-treated rat lung parenchyma.
Topics: Animals; Anti-Asthmatic Agents; Benzoquinones; Dextrans; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Heptanoic Acids; Imidazoles; Indazoles; Indomethacin; Leukotrienes; Lung; Male; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Serotonin; Tetrahydronaphthalenes; Thromboxane A2 | 1999 |
Thromboxane A(2) causes retarded clearance of aggregated protein in glomeruli of nephritic mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antibodies; Autoantibodies; Benzenesulfonates; Cells, Cultured; Cycloheptanes; Enzyme Inhibitors; Glomerular Mesangium; Hot Temperature; Imidazoles; Kidney Glomerulus; Lupus Nephritis; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Nephritis; Receptors, Thromboxane; Serum Albumin, Bovine; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane-A Synthase; Vasoconstrictor Agents | 2001 |
Production of thromboxane A2 and prostaglandin i2 affected by interaction of heat aggregated IgG, endothelial cells, and platelets in lupus nephritis.
Topics: Antigen-Antibody Complex; Blood Platelets; Cells, Cultured; Coculture Techniques; Complement C1q; Endothelium, Vascular; Epoprostenol; Hot Temperature; Humans; Imidazoles; Immunoglobulin G; Infant, Newborn; Lupus Nephritis; Male; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane-A Synthase | 2002 |