nadp has been researched along with quinazolines in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allegra, CJ; Chabner, BA; Drake, JC; Kovacs, JA; Masur, H; Swan, JC | 1 |
| Albrecht, AM; Hutchison, DJ | 1 |
| Lakshmanan, MR; Narindrasorasak, S | 1 |
| Jaffe, JJ; McCormack, JJ; Meymarian, E | 1 |
| Albrecht, AM; Biedler, JL; Hutchison, DJ | 1 |
| Beechem, JM; Bradrick, TD; Howell, EE | 1 |
| Cook, RJ | 1 |
| Cody, V; Galitsky, N; Gangjee, A; Kisliuk, RL; Li, R; Luft, JR; Pangborn, W; Queener, SF; Vasudevan, A; Vidwans, AP | 1 |
| Baccanari, DP; Chan, JH; Hardman, KD; Hong, JS; Howard, AJ; Kuyper, LF; Stewart, D; Tansik, RL; Whitlow, M | 1 |
| García-Martín, E; Gutiérrez-Merino, C; Martín-Romero, FJ | 1 |
| Cody, V; Galitsky, N; Gangjee, A; Luft, JR; Pangborn, W; Queener, SF | 1 |
| Anderson, KS; Atreya, CE; Chang, SY; Johnson, EF; Liang, PH; Williamson, J | 1 |
| Avery, MA; Carvalho, P; Gibellini, F; Hunter, WN; McLuskey, K | 1 |
| Chan, EC; Chua, TB; Ho, HK; Nelson, SD; New, LS; Yap, CW | 1 |
| An, K; Ishii, Y; Nishimura, Y; Yamada, H | 1 |
| Cheng, W; Hu, Y; Peng, P; Qiu, N; Sheng, R; Yuan, Y | 1 |
16 other study(ies) available for nadp and quinazolines
| Article | Year |
|---|---|
Activity of antifolates against Pneumocystis carinii dihydrofolate reductase and identification of a potent new agent.
Topics: Biological Transport; Folic Acid Antagonists; Kinetics; Methotrexate; NADP; Pneumocystis; Quinazolines; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1987 |
Folate reductase of the amethopterin-resistant Streptococcus faecium var. durans-Ak. I. Inhibition by amethopterin and methasquin, a new quinazoline antifolate.
Topics: Aspartic Acid; Chromatography, DEAE-Cellulose; Electrophoresis; Folic Acid Antagonists; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Molecular Weight; NADP; Potassium Chloride; Quinazolines; Streptococcus; Tetrahydrofolate Dehydrogenase | 1970 |
Conversion of retinyl methyl ether into retinol in the rat in vitro.
Topics: Aluminum; Animals; Edetic Acid; Enzyme Activation; Ethers; Intestinal Mucosa; Kinetics; Lithium; Liver; Magnesium; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Models, Chemical; NADP; Oxygenases; Pteridines; Quinazolines; Rats; Subcellular Fractions; Tritium; Vitamin A | 1972 |
Comparative properties of schistosomal and filarial dihydrofolate reductases.
Topics: Anthelmintics; Chromatography, Gel; Eukaryota; Filarioidea; Folic Acid Antagonists; Molecular Weight; NADP; Pyrimethamine; Quinazolines; Schistosoma mansoni; Structure-Activity Relationship; Suramin; Tetrahydrofolate Dehydrogenase; Trimethoprim | 1972 |
Two different species of dihydrofolate reductase in mammalian cells differentially resistant to amethopterin and methasquin.
Topics: Animals; Cell Line; Cricetinae; Drug Resistance; Folic Acid Antagonists; Hydrogen-Ion Concentration; In Vitro Techniques; Isoenzymes; Kinetics; Methotrexate; Molecular Weight; Mutagens; NADP; Quinazolines; Tetrahydrofolate Dehydrogenase | 1972 |
Unusual binding stoichiometries and cooperativity are observed during binary and ternary complex formation in the single active pore of R67 dihydrofolate reductase, a D2 symmetric protein.
Topics: Allosteric Regulation; Binding Sites; Calorimetry; Fluorescence Polarization; Folic Acid; Kinetics; Ligands; NADP; Protein Binding; Quinazolines; R Factors; Tetrahydrofolate Dehydrogenase | 1996 |
Use of 10-formyl-5,8-dideazafolate as substrate for rat 10-formyltetrahydrofolate dehydrogenase.
Topics: Acyltransferases; Animals; Folic Acid; Hydrolysis; Hydroxymethyl and Formyl Transferases; Leucovorin; Molecular Structure; NADP; Oxidoreductases Acting on CH-NH Group Donors; Phosphoribosylglycinamide Formyltransferase; Quinazolines; Rats; Spectrophotometry; Stereoisomerism | 1997 |
Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Division; Crystallography, X-Ray; Drug Design; Drug Screening Assays, Antitumor; Escherichia coli; Folic Acid Antagonists; Humans; Liver; Models, Molecular; Molecular Structure; NADP; Pneumocystis; Pyridines; Pyrimidines; Quinazolines; Rats; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Toxoplasma; Tumor Cells, Cultured | 1998 |
X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor.
Topics: Candida albicans; Crystallography, X-Ray; Folic Acid Antagonists; Models, Molecular; NADP; Niacinamide; Quinazolines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2001 |
Inhibition of oxidative stress produced by plasma membrane NADH oxidase delays low-potassium-induced apoptosis of cerebellar granule cells.
Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cell Membrane; Cell Survival; Cell-Free System; Cells, Cultured; Cerebellum; Cytoprotection; DNA Fragmentation; Enzyme Inhibitors; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; NADP; Neurons; Oxidative Stress; Potassium; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Superoxide Dismutase | 2002 |
Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase.
Topics: Crystallography, X-Ray; Folic Acid Antagonists; Models, Molecular; Molecular Structure; NADP; Pneumocystis; Pyrimidines; Quinazolines; Tetrahydrofolate Dehydrogenase | 2002 |
Probing electrostatic channeling in protozoal bifunctional thymidylate synthase-dihydrofolate reductase using site-directed mutagenesis.
Topics: Animals; Binding Sites; Catalysis; Crystallization; Enzyme Stability; Fluorodeoxyuridylate; Folic Acid; Hydrocarbons; Kinetics; Leishmania major; Methane; Models, Molecular; Molecular Structure; Multienzyme Complexes; Mutagenesis, Site-Directed; NADP; Quinazolines; Spectrophotometry; Static Electricity; Structure-Activity Relationship; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidylate Synthase | 2003 |
Inhibition of Leishmania major pteridine reductase by 2,4,6-triaminoquinazoline: structure of the NADPH ternary complex.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Electrons; Enzyme Inhibitors; Hydrogen Bonding; Leishmania major; Methotrexate; Models, Chemical; Models, Molecular; NADP; Oxidoreductases; Protein Conformation; Quinazolines | 2004 |
Interaction of lapatinib with cytochrome P450 3A5.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dealkylation; Humans; Hydroxylation; Lapatinib; Midazolam; NADP; Protein Kinase Inhibitors; Quinazolines; Testosterone | 2012 |
ATP serves as an endogenous inhibitor of UDP-glucuronosyltransferase (UGT): a new insight into the latency of UGT.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alamethicin; Animals; Catalytic Domain; Cetomacrogol; Endoplasmic Reticulum; Gefitinib; Glucuronosyltransferase; Humans; Male; Microsomes, Liver; NADP; Quinazolines; Rats; Rats, Sprague-Dawley; UDP-Glucuronosyltransferase 1A9 | 2012 |
Identification of novel 4-anilinoquinazoline derivatives as potent EGFR inhibitors both under normoxia and hypoxia.
Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; HT29 Cells; Humans; Molecular Docking Simulation; NADP; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Quinazolines; Structure-Activity Relationship | 2014 |