Compounds > nadolol

nadolol and metoprolol

nadolol has been researched along with metoprolol in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Charlton, SJ; Dickson, CJ; Duca, JS; Fairhurst, RA; Hornak, V; McKay, DJ; Pearlstein, RA; Reilly, J; Sandham, DA; Shaw, D; Sykes, DA; Velez-Vega, C1
Álvarez, M; Cheng, X; De Clercq, E; Gao, P; Liu, X; Luczkowiak, J; Menéndez-Arias, L; Pannecouque, C; Song, S; Sun, L; Zhan, P1
Avigliano, M; Carbajo, R; Crutcher, P; Morozzi, C; Pertusati, F; Sandoval, L; Sedláková, J; Serpi, M; Thomas, S; Valles-Ayoub, Y1
Ahuja, VT; Allen, J; Bristow, LJ; Bronson, JJ; Brown, JM; Camac, D; Dandapani, K; Dokania, M; Dzierba, CD; Easton, A; Elavazhagan, S; Gulianello, M; Hamman, BD; Hartz, RA; Hunihan, L; Kiefer, SE; Kostich, W; Kumar, CMV; Lewis, M; Lippy, JS; Macor, JE; Muckelbauer, JK; Nara, SJ; Pattipati, SN; Rajamani, R; Surti, N1
Borrego, D; Clercq, E; Frutos-Beltrán, E; Gao, S; Kang, D; Liu, X; López-Carrobles, N; Menéndez-Arias, L; Pannecouque, C; Río, JMD; Wei, F; Xu, S; Zhan, P; Zhang, J; Zhang, L; Zhao, F1

Reviews

1 review(s) available for nadolol and metoprolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for nadolol and metoprolol

ArticleYear
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Uncoupling the Structure-Activity Relationships of β2 Adrenergic Receptor Ligands from Membrane Binding.
    Journal of medicinal chemistry, 2016, 06-23, Volume: 59, Issue:12

    Topics: Binding Sites; Cell Membrane; Dose-Response Relationship, Drug; Humans; Ligands; Models, Molecular; Molecular Structure; Receptors, Adrenergic, beta-2; Structure-Activity Relationship

2016
Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H,3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase.
    Bioorganic & medicinal chemistry, 2019, 09-01, Volume: 27, Issue:17

    Topics: Anti-HIV Agents; Caco-2 Cells; Cell Line; Cell Membrane Permeability; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; HIV Integrase; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Models, Molecular; Molecular Structure; Quinazolinones; Ribonuclease H, Human Immunodeficiency Virus; Structure-Activity Relationship

2019
Targeting GNE Myopathy: A Dual Prodrug Approach for the Delivery of
    Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17

    Topics: Animals; Caco-2 Cells; Cell Survival; Cells, Cultured; CHO Cells; Cricetulus; Distal Myopathies; Dose-Response Relationship, Drug; Drug Delivery Systems; Hexosamines; Humans; Molecular Structure; N-Acetylneuraminic Acid; Phosphotransferases (Alcohol Group Acceptor); Prodrugs; Structure-Activity Relationship; Sugar Phosphates

2019
Discovery, Structure-Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain.
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Caco-2 Cells; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Molecular Structure; Neuralgia; Protein Kinases; Protein Serine-Threonine Kinases; Structure-Activity Relationship

2021
Design, synthesis, and biological evaluation of novel double-winged galloyl derivatives as HIV-1 RNase H inhibitors.
    European journal of medicinal chemistry, 2022, Oct-05, Volume: 240

    Topics: Anti-HIV Agents; HIV Reverse Transcriptase; HIV-1; Humans; Reverse Transcriptase Inhibitors; Ribonuclease H; Ribonuclease H, Human Immunodeficiency Virus; Structure-Activity Relationship

2022