Page last updated: 2024-08-17

nad and xanthine

nad has been researched along with xanthine in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199013 (22.03)18.7374
1990's21 (35.59)18.2507
2000's19 (32.20)29.6817
2010's6 (10.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heyde, E; Morrison, JF; Nagabhushanam, A; Vonarx, M1
Alamillo, JM; Cárdenas, J; Pérez-Vicente, R; Pineda, M1
Kamiński, ZW; Zakrzewska, B1
Hedstrom, L; Wang, CC1
Cassens, RG; Faustman, C1
Alaoui Jamali, MA; Boudreau, A; Castonguay, A; Lautier, D; Poirier, D; Poirier, G1
Coulombe, RA; Grover, TA; Keller, RJ; Piette, LH; Sharma, RP1
Fridovich, I; Ivancheva, E; Liochev, S1
Ikegami, T; Natsumeda, Y; Weber, G; Yamada, Y1
Natsumeda, Y; Weber, G; Yamada, Y; Yamaji, Y1
Mela-Riker, L; Vlessis, AA1
Massey, V; Nishino, T; Schopfer, LM1
Kootstra, G; Maessen, JG; van der Vusse, GJ; Vork, M1
Bruguera, P; Canela, EI; Lopez-Cabrera, A1
Gullapalli, S; Khandke, L; Patole, MS; Ramasarma, T1
Armiger, LC; Hollis, DG; Seelye, RN1
Jezewska, MM; Kamiński, ZW1
Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T1
Aggarwal, S; Singh, N1
Bory, C; Boulieu, R; Chantin, C1
Nishino, T; Okamoto, K1
den Besten, PJ; Lemaire, P; Livingstone, DR1
Antonino, LC; Wu, JC1
Hunt, J; Massey, V1
Pugh, ME; Skibo, EB1
Gustafson, DL; Pritsos, CA1
Dalal, NS; Shi, X1
Bollinger, RR; Canada, AT; Coleman, LR; Fabian, MA1
Bray, RC; Burke, JF; Chovnick, A; Doyle, WA; Dutton, FL; Whittle, JR1
Hedstrom, L; Wang, W1
Dambrova, M; Uhlén, S; Wikberg, JE1
Afanas'ev, IB; Korkina, LG; Ostrachovitch, EA1
Tampo, Y; Tsukamoto, M; Yonaha, M1
Blake, DR; Doel, JJ; Eisenthal, R; Godber, BL; Harrison, R; Sapkota, GP; Stevens, CR1
Crause, P; Gloe, T; Keller, M; Pohl, U; Sohn, HY1
Cahoon, M; Hedstrom, L; McMillan, FM; Petsko, GA; Ringe, D; White, A1
Baumane, L; Dambrova, M; Kalvinsh, I; Kiuru, A; Wikberg, JE1
Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM1
Ampola, F; Gueli, MC; Nicotra, CM; Paganini, A; Taibi, G1
Caron, PR; DeCenzo, MT; Futer, O; Livingston, DJ; Nimmesgern, E; Raybuck, SA; Sintchak, MD1
Di Fonzo, N; Laus, MN; Passarella, S; Pastore, D1
Luecke, H; Prosise, GL1
Ichida, K; Matsumura, T; Yamaguchi, Y1
Aikoh, H1
AGUSTINARZENO, J; DEFERNANDEZBLANCO, JF; FERNANDEZBLANCO, E1
Jeong, HY; Kim, CD1
Hille, R; Igarashi, K; Leimkühler, S; Nishino, T; Stockert, AL1
Cui, H; Li, H; Liu, X; Zweier, JL1
Moriwaki, Y; Takahashi, S; Yamamoto, T1
Baghiani, A; Benboubetra, M; Harrison, R1
Berg, A; Boitz, JM; Dobie, F; Jardim, A1
Bando, M; Kawai, K; Obazawa, H; Oka, M; Takehana, M1
Hedstrom, L; Josephine, HR; Riera, TV; Wang, W1
Bittner, F; Kaspari, K; Mendel, RR; Rethmeier, R; Stagge, S; Zarepour, M1
Bernhardt, PV; Kalimuthu, P; Leimkühler, S1
Anderson, WF; Binkowski, TA; Gollapalli, DR; Gornicki, P; Hedstrom, L; Jedrzejczak, R; Joachimiak, A; Kim, Y; Kuhn, ML; Mack, JC; Makowska-Grzyska, M; Maltseva, N; Mulligan, R; Wang, XK; Wilton, R; Wu, R; Zhang, R1
Hille, R; Komatsu, T; Lee, MC; Velayutham, M; Zweier, JL1
Maia, LB; Mira, L; Moura, JJ; Pereira, V1
Anthony, S; Ji, Y; Peterson, JR1

Reviews

2 review(s) available for nad and xanthine

ArticleYear
[Xanthine dehydrogenase (xanthine oxidase)].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1

    Topics: Allopurinol; Animals; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Free Radicals; Humans; Hyperuricemia; NAD; Reactive Oxygen Species; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase

2003
Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid).
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 356, Issue:1-2

    Topics: Acetyl Coenzyme A; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Ethanol; Humans; Hyperuricemia; Hypoxanthine; Lactic Acid; NAD; Oxidation-Reduction; Uric Acid; Xanthine; Xanthine Dehydrogenase

2005

Trials

1 trial(s) available for nad and xanthine

ArticleYear
Xylitol-induced increase in the concentration of oxypurines and its mechanism.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:6

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cytosol; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Inosine; Intestine, Small; Lactates; Lactic Acid; Liver; Male; Middle Aged; NAD; Phosphates; Pyrazinamide; Pyruvates; Pyruvic Acid; Saline Solution, Hypertonic; Serum Albumin; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines; Xylitol

1995

Other Studies

56 other study(ies) available for nad and xanthine

ArticleYear
Studies on inosine monophosphate dehydrogenase. Steady state kinetics.
    Biochimica et biophysica acta, 1976, May-13, Volume: 429, Issue:3

    Topics: Enterobacter; Guanine Nucleotides; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Lithium; NAD; Nicotinic Acids; Osmolar Concentration; Potassium; Protein Binding; Ribonucleotides; Xanthine; Xanthines

1976
Purification and substrate inactivation of xanthine dehydrogenase from Chlamydomonas reinhardtii.
    Biochimica et biophysica acta, 1992, Sep-15, Volume: 1117, Issue:2

    Topics: Acetaldehyde; Adenine; Animals; Chlamydomonas reinhardtii; Enzyme Activation; Hypoxanthine; Hypoxanthines; NAD; NADP; Spectrophotometry; Xanthine; Xanthine Dehydrogenase; Xanthines

1992
Involvement of histidine residues in catalytic activity of xanthine dehydrogenase from hen liver.
    The International journal of biochemistry, 1992, Volume: 24, Issue:3

    Topics: 2,6-Dichloroindophenol; Animals; Chickens; Diethyl Pyrocarbonate; Enzyme Activation; Female; Histidine; Kinetics; Liver; NAD; Oxidation-Reduction; Photochemistry; Structure-Activity Relationship; Xanthine; Xanthine Dehydrogenase; Xanthines

1992
Mycophenolic acid and thiazole adenine dinucleotide inhibition of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: implications on enzyme mechanism.
    Biochemistry, 1990, Jan-30, Volume: 29, Issue:4

    Topics: Adenine Nucleotides; Animals; Binding Sites; Binding, Competitive; IMP Dehydrogenase; Isomerism; Ketone Oxidoreductases; Kinetics; Mycophenolic Acid; NAD; Ribonucleotides; Tritrichomonas; Xanthine

1990
The effect of cattle breed and muscle type on discoloration and various biochemical parameters in fresh beef.
    Journal of animal science, 1991, Volume: 69, Issue:1

    Topics: Animals; Breeding; Cattle; Glutathione; Glutathione Disulfide; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Lipid Metabolism; Male; Meat; Metmyoglobin; Muscles; NAD; Oxidation-Reduction; Pigments, Biological; Sulfhydryl Compounds; Xanthine; Xanthines

1991
Stimulation of poly(ADP-ribose) synthesis by free radicals in C3H10T1/2 cells: relationship with NAD metabolism and DNA breakage.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1990, Volume: 68, Issue:3

    Topics: Alkaline Phosphatase; Animals; Benzamides; Cell Line; Chromatography, High Pressure Liquid; Clone Cells; DNA Damage; Free Radicals; Gamma Rays; Hydrogen Peroxide; Hydrogen-Ion Concentration; Mice; NAD; Nucleoside Diphosphate Sugars; Phosphoric Diester Hydrolases; Poly Adenosine Diphosphate Ribose; Superoxides; Tritium; Xanthine; Xanthine Oxidase; Xanthines

1990
Importance of hydroxyl radical in the vanadium-stimulated oxidation of NADH.
    Free radical biology & medicine, 1989, Volume: 6, Issue:1

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; NAD; Oxidation-Reduction; Spectrophotometry; Spin Labels; Superoxides; Vanadates; Vanadium; Xanthine; Xanthine Oxidase; Xanthines

1989
Effects of vanadate on the oxidation of NADH by xanthine oxidase.
    Archives of biochemistry and biophysics, 1989, Feb-15, Volume: 269, Issue:1

    Topics: Animals; Catalysis; Cattle; Enzyme Activation; NAD; Oxidation-Reduction; Structure-Activity Relationship; Substrate Specificity; Superoxides; Vanadates; Xanthine; Xanthine Oxidase; Xanthines

1989
Kinetic properties of IMP dehydrogenase purified from rat hepatoma 3924A.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Animals; Dose-Response Relationship, Drug; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Kinetics; Liver Neoplasms, Experimental; NAD; Rats; Ribonucleotides; Tumor Cells, Cultured; Xanthine

1989
Two distinct target sites on IMP dehydrogenase in chemotherapy.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Drug Synergism; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Liver Neoplasms, Experimental; NAD; Nucleotides; Rats; Ribonucleotides; Temperature; Time Factors; Tumor Cells, Cultured; Xanthine

1989
Potential role of mitochondrial calcium metabolism during reperfusion injury.
    The American journal of physiology, 1989, Volume: 256, Issue:6 Pt 1

    Topics: Animals; Calcium; Catalase; Hypoxanthine; Hypoxanthines; Kidney; Kinetics; Male; Mitochondria; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Reperfusion Injury; Superoxide Dismutase; Xanthine; Xanthines

1989
Rapid reaction studies on the reduction and oxidation of chicken liver xanthine dehydrogenase by the xanthine/urate and NAD/NADH couples.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: Animals; Chickens; Dithionite; Electron Transport; Flavin-Adenine Dinucleotide; Ketone Oxidoreductases; Kinetics; Liver; NAD; Oxidation-Reduction; Spectrophotometry; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines

1988
Nucleotides, nucleosides, and oxypurines in human kidneys measured by use of reversed-phase high-performance liquid chromatography.
    Clinical chemistry, 1988, Volume: 34, Issue:6

    Topics: Adenine Nucleotides; Adenosine; Chromatography, High Pressure Liquid; Coenzyme A; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Kidney Cortex; Kidney Transplantation; NAD; NADP; Nucleosides; Nucleotides; Quality Control; Xanthine; Xanthines

1988
Kinetic mechanism of chicken liver xanthine dehydrogenase.
    The Biochemical journal, 1988, Jan-01, Volume: 249, Issue:1

    Topics: Animals; Chickens; Computer Simulation; Ketone Oxidoreductases; Kinetics; Liver; Models, Chemical; NAD; Xanthine; Xanthine Dehydrogenase; Xanthines

1988
Vanadate-stimulated NADH oxidation by xanthine oxidase: an intrinsic property.
    Archives of biochemistry and biophysics, 1986, Feb-01, Volume: 244, Issue:2

    Topics: Animals; Cattle; Dose-Response Relationship, Drug; Hydrogen Peroxide; Hydrogen-Ion Concentration; NAD; Oxidation-Reduction; Oxidoreductases; Oxygen; Superoxide Dismutase; Vanadates; Vanadium; Xanthine; Xanthine Oxidase; Xanthines

1986
Regional variations in the "adenine/oxypurine" pool of the heart in normoxia and oxygen deficiency.
    Experimental pathology, 1986, Volume: 30, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Animals; Chromatography, High Pressure Liquid; Dogs; Energy Metabolism; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine Monophosphate; Male; Myocardium; NAD; Uric Acid; Xanthine; Xanthines

1986
Effect of NADH on hypoxanthine hydroxylation by native NAD+-dependent xanthine oxidoreductase of rat liver, and the possible biological role of this effect.
    The Biochemical journal, 1981, Dec-15, Volume: 200, Issue:3

    Topics: Animals; Hydroxylation; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Ketone Oxidoreductases; Kinetics; Liver; Male; NAD; Rats; Rats, Inbred Strains; Spectrophotometry; Time Factors; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines

1981
The effect of active oxygen generated by xanthine/xanthine oxidase on genes and signal transduction in mouse epidermal JB6 cells.
    International journal of cancer, 1995, Jul-04, Volume: 62, Issue:1

    Topics: Animals; Cells, Cultured; Gene Expression Regulation; Genes, myc; Mice; NAD; Poly(ADP-ribose) Polymerases; Protein Kinase C; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Superoxide Dismutase; Xanthine; Xanthine Oxidase; Xanthines

1995
Abnormal purine and pyrimidine metabolism in inherited superactivity of PRPP synthetase.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Adenine Nucleotides; Allopurinol; Child; Erythrocytes; Female; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; NAD; Nuclear Family; Purine-Pyrimidine Metabolism, Inborn Errors; Reference Values; Ribonucleotides; Ribose-Phosphate Pyrophosphokinase; Uric Acid; Uridine; Uridine Diphosphate Glucose; Xanthine; Xanthines

1994
Mechanism of inhibition of xanthine oxidase with a new tight binding inhibitor.
    The Journal of biological chemistry, 1995, Apr-07, Volume: 270, Issue:14

    Topics: Isomerism; Kinetics; NAD; Oxidation-Reduction; Triazines; Xanthine; Xanthine Oxidase; Xanthines

1995
NADPH-, NADH- and cumene hydroperoxide-dependent metabolism of benzo[a]pyrene by pyloric caeca microsomes of the sea star Asterias rubens L. (Echinodermata: Asteroidea).
    Xenobiotica; the fate of foreign compounds in biological systems, 1994, Volume: 24, Issue:10

    Topics: Animals; Benzene Derivatives; Benzo(a)pyrene; Epoxide Hydrolases; Kinetics; Microsomes; NAD; NADP; Phenols; Proteins; Pylorus; Quinones; Starfish; Trichloroepoxypropane; Xanthine; Xanthine Oxidase; Xanthines

1994
Human IMP dehydrogenase catalyzes the dehalogenation of 2-fluoro- and 2-chloroinosine 5'-monophosphate in the absence of NAD.
    Biochemistry, 1994, Feb-22, Volume: 33, Issue:7

    Topics: Adenosine Deaminase; Binding, Competitive; Catalysis; Chromatography, High Pressure Liquid; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Magnetic Resonance Spectroscopy; NAD; Ribonucleotides; Spectrophotometry, Ultraviolet; Xanthine

1994
Studies of the reductive half-reaction of milk xanthine dehydrogenase.
    The Journal of biological chemistry, 1994, Jul-22, Volume: 269, Issue:29

    Topics: Animals; Cattle; Milk; NAD; Oxidation-Reduction; Spectrum Analysis; Xanthine; Xanthine Dehydrogenase; Xanthines; Xanthopterin

1994
Inosine monophosphate dehydrogenase from porcine (Sus scrofa domestica) thymus: purification and properties.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1993, Volume: 105, Issue:2

    Topics: Adenosine Monophosphate; Amino Acids; Animals; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Guanosine Monophosphate; Hydrogen-Ion Concentration; IMP Dehydrogenase; Inosine Monophosphate; Molecular Weight; NAD; Ribonucleotides; Swine; Thymus Gland; Xanthine

1993
Kinetics and mechanism of mitomycin C bioactivation by xanthine dehydrogenase under aerobic and hypoxic conditions.
    Cancer research, 1993, Nov-15, Volume: 53, Issue:22

    Topics: Aerobiosis; Anaerobiosis; Animals; Biotransformation; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Mice; Mice, Nude; Mitomycin; NAD; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines

1993
Vanadate-mediated hydroxyl radical generation from superoxide radical in the presence of NADH: Haber-Weiss vs Fenton mechanism.
    Archives of biochemistry and biophysics, 1993, Volume: 307, Issue:2

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; NAD; Superoxides; Vanadates; Xanthine; Xanthine Oxidase; Xanthines

1993
Adenine nucleotides of ischemic intestine do not reflect injury.
    The Journal of surgical research, 1993, Volume: 55, Issue:4

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Hot Temperature; Hypoxanthine; Hypoxanthines; Intestinal Diseases; Intestinal Mucosa; Intestines; Ischemia; Kinetics; Male; NAD; NADP; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors; Xanthine; Xanthines

1993
Properties of xanthine dehydrogenase variants from rosy mutant strains of Drosophila melanogaster and their relevance to the enzyme's structure and mechanism.
    European journal of biochemistry, 1996, Aug-01, Volume: 239, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Coenzymes; Conserved Sequence; Cross Reactions; Drosophila melanogaster; Enzyme Activation; Genetic Variation; Kinetics; Metalloproteins; Molecular Sequence Data; Molybdenum Cofactors; Mutagenesis, Site-Directed; Mutation; NAD; Oxidation-Reduction; Pteridines; Sequence Homology, Amino Acid; Structure-Activity Relationship; Xanthine; Xanthine Dehydrogenase; Xanthines

1996
Kinetic mechanism of human inosine 5'-monophosphate dehydrogenase type II: random addition of substrates and ordered release of products.
    Biochemistry, 1997, Jul-15, Volume: 36, Issue:28

    Topics: Humans; Hydrolysis; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Molecular Structure; NAD; Oxidation-Reduction; Ribonucleotides; Spectrometry, Fluorescence; Substrate Specificity; Xanthine

1997
Characterization of guanoxabenz reducing activity in rat brain.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:4

    Topics: Allopurinol; Animals; Antihypertensive Agents; Binding, Competitive; Cerebral Cortex; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Guanabenz; Male; NAD; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Synaptic Membranes; Xanthine

1998
Lucigenin is a mediator of cytochrome C reduction but not of superoxide production.
    Archives of biochemistry and biophysics, 1999, Jun-15, Volume: 366, Issue:2

    Topics: Acridines; Animals; Cattle; Cytochrome c Group; Hydrogen-Ion Concentration; Luminescent Measurements; NAD; Oxidation-Reduction; Superoxides; Xanthine; Xanthine Oxidase

1999
Superoxide production from paraquat evoked by exogenous NADPH in pulmonary endothelial cells.
    Free radical biology & medicine, 1999, Volume: 27, Issue:5-6

    Topics: Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Flavoproteins; Imidazoles; Interleukin-1; Luminescent Measurements; Lung; NAD; NADP; Oxidoreductases; Paraquat; Pyrazines; Spectrophotometry; Succinic Acid; Superoxide Dismutase; Superoxides; Swine; Xanthine

1999
Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase.
    The Journal of biological chemistry, 2000, Mar-17, Volume: 275, Issue:11

    Topics: Anaerobiosis; Animals; Biphenyl Compounds; Catalytic Domain; Cattle; Flavin-Adenine Dinucleotide; Flavoproteins; Kinetics; Metalloproteins; Milk; Molybdenum; NAD; Nitric Oxide; Nitrites; Onium Compounds; Oxidation-Reduction; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase

2000
Pitfalls of using lucigenin in endothelial cells: implications for NAD(P)H dependent superoxide formation.
    Free radical research, 2000, Volume: 32, Issue:3

    Topics: Acridines; Arsenicals; Cells, Cultured; Cytochrome c Group; Imidazoles; Luminescent Measurements; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Neutrophils; Onium Compounds; Pyrazines; Superoxides; Umbilical Veins; Xanthine; Xanthine Oxidase

2000
Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
    Biochemistry, 2000, Apr-18, Volume: 39, Issue:15

    Topics: Amino Acid Sequence; Animals; Binding Sites; Borrelia burgdorferi Group; Catalytic Domain; Crystallography, X-Ray; Cysteine; Drug Design; Humans; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Motion; NAD; Pliability; Protein Conformation; Ribonucleotides; Sequence Alignment; Solvents; Static Electricity; Structure-Activity Relationship; Sulfates; Xanthine

2000
N-Hydroxyguanidine compound 1-(3,4-dimethoxy- 2-chlorobenzylideneamino)-3-hydroxyguanidine inhibits the xanthine oxidase mediated generation of superoxide radical.
    Archives of biochemistry and biophysics, 2000, May-01, Volume: 377, Issue:1

    Topics: Allopurinol; Animals; Binding Sites; Catalysis; Cattle; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Guanidines; Hydroxylamines; Inhibitory Concentration 50; Kinetics; Milk; Models, Chemical; Molybdenum; NAD; Onium Compounds; Oxidation-Reduction; Oxygen; Reperfusion Injury; Superoxides; Uric Acid; Xanthine; Xanthine Oxidase

2000
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
    Teratogenesis, carcinogenesis, and mutagenesis, 2001, Volume: 21, Issue:2

    Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chromatography, Gas; Cytosol; Diet; Enzyme Inhibitors; Ethanol; Free Radicals; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Male; Meat; NAD; Neoplasms; Niacinamide; Phosphodiesterase Inhibitors; Prostate; Prostatic Neoplasms; Purines; Rats; Rats, Sprague-Dawley; Spin Trapping; Temperature; Theobromine; Theophylline; Time Factors; Vasodilator Agents; Xanthine; Xanthine Oxidase

2001
Xanthine oxidase catalyzes the synthesis of retinoic acid.
    Journal of enzyme inhibition, 2001, Volume: 16, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Milk; Molecular Conformation; NAD; Oxygen; Retinaldehyde; Tretinoin; Uric Acid; Xanthine; Xanthine Oxidase

2001
A mutational analysis of the active site of human type II inosine 5'-monophosphate dehydrogenase.
    Biochimica et biophysica acta, 2002, Jan-31, Volume: 1594, Issue:1

    Topics: Binding Sites; Catalysis; Hydrolysis; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; NAD; Ribonucleotides; Xanthine

2002
Reactive oxygen species inhibit the succinate oxidation-supported generation of membrane potential in wheat mitochondria.
    FEBS letters, 2002, Apr-10, Volume: 516, Issue:1-3

    Topics: Kinetics; Membrane Potentials; Mersalyl; Mitochondria; Models, Biological; NAD; Oxidative Stress; Reactive Oxygen Species; Succinates; Succinic Acid; Triticum; Xanthine; Xanthine Oxidase

2002
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
    Journal of molecular biology, 2003, Feb-14, Volume: 326, Issue:2

    Topics: Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Mycophenolic Acid; NAD; Protein Conformation; Ribavirin; Ribonucleotides; Tritrichomonas foetus; Xanthine

2003
Reduction of mercuric ion in vitro by superoxide anion.
    Physiological chemistry and physics and medical NMR, 2002, Volume: 34, Issue:2

    Topics: Ethylenediamines; Ions; Mercury; Methylphenazonium Methosulfate; Multienzyme Complexes; NAD; Nitroblue Tetrazolium; Oxidation-Reduction; Reproducibility of Results; Riboflavin; Sensitivity and Specificity; Superoxides; Xanthine; Xanthine Oxidase

2002
[7-(3-(METHYL-OXYETHYLAMINE)-2-OXYPROPYL)-1, 3-DIMETHYL-XANTHINE NICOTINATE IN CHRONIC OBLITERATING ANGIOPATHIES].
    La Semana medica, 1963, Nov-28, Volume: 123

    Topics: Arteriosclerosis; Arteriosclerosis Obliterans; Cholesterol; Coronary Disease; Humans; Intracranial Arteriosclerosis; Lipid Metabolism; NAD; Niacin; Nicotinic Acids; Pharmacology; Theophylline; Toxicology; Vascular Diseases; Vasodilator Agents; Vasomotor System; Xanthine

1963
p22phox-derived superoxide mediates enhanced proliferative capacity of diabetic vascular smooth muscle cells.
    Diabetes research and clinical practice, 2004, Volume: 64, Issue:1

    Topics: Animals; Aorta; Base Sequence; Cell Division; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA Primers; Gene Expression Regulation, Enzymologic; Male; Membrane Transport Proteins; Muscle, Smooth, Vascular; NAD; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Oligonucleotides, Antisense; Phosphoproteins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Transfection; Xanthine

2004
The role of active site glutamate residues in catalysis of Rhodobacter capsulatus xanthine dehydrogenase.
    The Journal of biological chemistry, 2004, Sep-24, Volume: 279, Issue:39

    Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Dithionite; Dose-Response Relationship, Drug; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Mutation; NAD; Oxygen; Protein Binding; Protein Structure, Tertiary; Rhodobacter capsulatus; Spectrophotometry; Substrate Specificity; Sulfur; Time Factors; Ultraviolet Rays; Uric Acid; Xanthine; Xanthine Dehydrogenase

2004
Xanthine oxidase catalyzes anaerobic transformation of organic nitrates to nitric oxide and nitrosothiols: characterization of this mechanism and the link between organic nitrate and guanylyl cyclase activation.
    The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17

    Topics: Anions; Benzaldehydes; Binding Sites; Biotransformation; Catechols; Electrochemistry; Electrodes; Electron Spin Resonance Spectroscopy; Enzyme Activation; Flavins; Glutathione Transferase; Guanylate Cyclase; Hydrogen-Ion Concentration; Immunoassay; Kinetics; Models, Chemical; Myocardial Ischemia; NAD; Nitrates; Nitric Oxide; Nitrites; Protein Binding; S-Nitrosothiols; Time Factors; Xanthine; Xanthine Oxidase

2005
Purification and partial characterisation of camel milk xanthine oxidoreductase.
    Archives of physiology and biochemistry, 2003, Volume: 111, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Camelus; Cattle; Dithiothreitol; Female; Humans; Milk; Molecular Weight; Molybdenum; NAD; Oxidoreductases; Pterins; Reactive Oxygen Species; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase

2003
Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.
    Molecular and biochemical parasitology, 2007, Volume: 152, Issue:1

    Topics: Amino Acid Sequence; Animals; Enzyme Inhibitors; Escherichia coli; Guanosine Monophosphate; Inosine Monophosphate; Leishmania donovani; Microbodies; Microscopy, Confocal; Mycophenolic Acid; NAD; Peroxisome-Targeting Signal 1 Receptor; Phylogeny; Protein Binding; Protozoan Proteins; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Ribonucleotides; Sequence Alignment; Subcellular Fractions; Substrate Specificity; Xanthine

2007
NADH photo-oxidation is enhanced by a partially purified lambda-crystallin fraction from rabbit lens.
    Molecular vision, 2007, Sep-18, Volume: 13

    Topics: Animals; Crystallins; In Vitro Techniques; Lens, Crystalline; NAD; Oxidation-Reduction; Rabbits; Superoxides; Ultraviolet Rays; Xanthine; Xanthine Oxidase

2007
A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases.
    Biochemistry, 2008, Aug-19, Volume: 47, Issue:33

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cryptosporidium parvum; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Molecular Conformation; Molecular Sequence Data; NAD; Protein Binding; Ribonucleotides; Xanthine

2008
Xanthine dehydrogenase AtXDH1 from Arabidopsis thaliana is a potent producer of superoxide anions via its NADH oxidase activity.
    Plant molecular biology, 2010, Volume: 72, Issue:3

    Topics: Arabidopsis; NAD; Oxidation-Reduction; Pichia; Recombinant Proteins; Superoxides; Xanthine; Xanthine Dehydrogenase

2010
Xanthine dehydrogenase electrocatalysis: autocatalysis and novel activity.
    The journal of physical chemistry. B, 2011, Mar-24, Volume: 115, Issue:11

    Topics: Allopurinol; Biocatalysis; Electrochemistry; Electrodes; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Hypoxanthine; Imines; NAD; Oxidation-Reduction; Rhodobacter capsulatus; Uric Acid; Xanthine; Xanthine Dehydrogenase

2011
Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
    Biochemistry, 2012, Aug-07, Volume: 51, Issue:31

    Topics: Amino Acid Sequence; Apoenzymes; Bacillus anthracis; Benzimidazoles; Catalytic Domain; Enzyme Inhibitors; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Mycophenolic Acid; NAD; Protein Binding; Ribonucleotides; Triazoles; Xanthine

2012
Measurement and characterization of superoxide generation from xanthine dehydrogenase: a redox-regulated pathway of radical generation in ischemic tissues.
    Biochemistry, 2014, Oct-21, Volume: 53, Issue:41

    Topics: Animals; Animals, Inbred Strains; Avian Proteins; Biocatalysis; Cattle; Chickens; Dogs; Electron Spin Resonance Spectroscopy; Heart Ventricles; Isoenzymes; Kinetics; Milk Proteins; Models, Biological; Myocardial Ischemia; NAD; Oxidation-Reduction; Sarcoplasmic Reticulum; Superoxides; Xanthine; Xanthine Dehydrogenase

2014
Nitrite reductase activity of rat and human xanthine oxidase, xanthine dehydrogenase, and aldehyde oxidase: evaluation of their contribution to NO formation in vivo.
    Biochemistry, 2015, Jan-27, Volume: 54, Issue:3

    Topics: Aldehyde Oxidase; Aldehydes; Animals; Biocatalysis; Endothelial Cells; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Microvessels; Models, Molecular; NAD; Nitric Oxide; Nitrite Reductases; Nitrites; Oxidation-Reduction; Oxygen; Rats, Sprague-Dawley; Substrate Specificity; Time Factors; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase

2015
Use of Inosine Monophosphate Dehydrogenase Activity Assay to Determine the Specificity of PARP-1 Inhibitors.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1608

    Topics: Animals; Biological Assay; Humans; IMP Dehydrogenase; Inosine Monophosphate; NAD; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Ribonucleotides; Xanthine

2017