nad has been researched along with tryptophan in 354 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 181 (51.13) | 18.7374 |
| 1990's | 49 (13.84) | 18.2507 |
| 2000's | 52 (14.69) | 29.6817 |
| 2010's | 41 (11.58) | 24.3611 |
| 2020's | 31 (8.76) | 2.80 |
| Authors | Studies |
|---|---|
| Friedrich, B; Friedrich, CG; Schlegel, HG | 1 |
| Obrebska, M; Wrońska-Nofer, T | 1 |
| Badawy, AA | 4 |
| Verjee, ZH | 1 |
| Shibata, Y | 1 |
| Badawy, AA; Evans, M; Punjani, NF | 1 |
| Casida, JE; Engel, JL; Moscioni, AD | 1 |
| Seed, JR; Stibbs, HH | 1 |
| Iweibo, I; Weiner, H | 2 |
| Gaertner, FH; Shetty, AS | 2 |
| Pfleiderer, G | 1 |
| Beaudoin, AR | 1 |
| Rao, BS; Satyanarayana, U | 3 |
| Narasinga Rao, BS; Satyanarayana, U | 1 |
| Schellenberg, KA | 3 |
| Streffer, C | 4 |
| Bapurao, S; Krishnaswamy, K | 1 |
| Steinberg, IZ | 2 |
| Argoudelis, CJ | 1 |
| Forster, LS; O'Neal, CC; Rupley, JA; Torikata, T | 1 |
| Forster, LS; Johnson, RE; Rupley, JA; Torikata, T | 1 |
| Collier, RJ; DeLange, RJ; Drazin, RE; Williams, LC | 1 |
| Barton, RA; Chaffin, WL; Jacobson, EL; Jacobson, MK | 1 |
| Fan, CC; Plaut, GW; Tomcho, LA | 1 |
| Pewnim, T; Seifert, J | 1 |
| Rao, CM; Zigler, JS | 1 |
| Borriello, SP; Lobban, MD | 1 |
| Disher, RM; Ramdas, L; Wensel, TG | 1 |
| Kido, R; Okuno, E | 1 |
| Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G | 1 |
| Bender, DA; Danielian, PS; Njagi, EN | 1 |
| Chumachenko, YV; Demchenko, AP; Sytnik, AI | 1 |
| Eftink, MR; Emerich, DW; Ghiron, CA; Waters, JK | 1 |
| Gonnelli, M; Strambini, GB | 1 |
| Galley, WC; Gonnelli, M; Strambini, GB | 1 |
| Chambers, JE; Snawder, JE | 1 |
| Hove-Jensen, B | 1 |
| Kiyohara, Y; Sano, K; Shin, M; Shirasawa, K; Umezawa, C | 1 |
| Bender, DA | 2 |
| Fu, CS; Jacob, RA; McKee, RW; Swendseid, ME | 1 |
| Aoki, N; Inoue, K; Sanada, H; Wada, O | 1 |
| Gabellieri, E; Strambini, GB | 1 |
| Grahn, H; Grätz, R; Kröger, H | 4 |
| Hayakawa, T; Iwai, K; Murata, K; Shibata, K | 1 |
| Bender, DA; Olufunwa, R | 1 |
| Kitos, PA; Kushaba-Rugaaju, S | 1 |
| Kanoh, T; Mizoguchi, I; Suzuki, T | 1 |
| Ibrahim, M; Lohmann, C; Lohmann, W | 1 |
| Eftink, MR; Hagaman, KA | 1 |
| el Kebbaj, MS; Latruffe, N; Monsigny, M; Obrenovitch, A | 1 |
| Haba, K; Maeda, Y; Sano, K; Shin, M; Umezawa, C | 1 |
| De Bersaques, J | 1 |
| Palmieri, F; Quagliariello, E | 1 |
| Badawy, AA; Evans, M | 2 |
| Nath, MC; Shastri, NV | 1 |
| Oguri, S | 1 |
| Kaseda, H; Kido, R; Ora, H | 1 |
| Berry, LJ | 1 |
| Maayan, ML; Rosenberg, IN | 1 |
| Sawyer, B; Slater, TF; Sträuli, U | 1 |
| Cross, DG; Fisher, HF | 1 |
| Ahmad, F; Moat, AG | 1 |
| Glombitza, KW | 1 |
| Hayaishi, O; Higuchi, K | 1 |
| Gholson, RK; Shimoyama, M; Yamaguchi, K | 1 |
| Keleti, T | 1 |
| Greenbaum, AL; Pinder, S | 1 |
| Rosenbloom, J | 1 |
| McDonald, JW; Rathbun, FJ; Stewart, HB | 1 |
| Moses, D; Weiner, M | 1 |
| Ichiyama, A; Nakamura, S; Nishizuka, Y | 2 |
| Penzer, GR; Radda, GK | 1 |
| Bray, D; Kapoor, M | 1 |
| Moore, TC; Shaner, CA | 1 |
| Loverde, A; Strittmatter, P | 1 |
| Hayaishi, O; Ichiyama, A; Ijichi, H | 1 |
| Asakawa, T; Wada, H; Yamano, T | 1 |
| Elzinga, M; Lam, KW; Swann, D | 1 |
| Sakamoto, H; Shimoyama, M; Takeuchi, T; Ueda, I; Yamaguchi, K | 1 |
| Griffin, MJ | 1 |
| Cassen, T; Kearns, DR | 1 |
| Lojkin, ME | 1 |
| Brown, RR; Madsen, PO; Price, JM; Wolf, H | 1 |
| Brown, AT; Wagner, C | 1 |
| Brand, L; Conrad, RH; Heitz, JR | 1 |
| Huc, C; Olomucki, A; Pho, DB; Thoai, NV | 1 |
| Powanda, MC; Wannemacher, RW | 2 |
| Favilla, R; Luisi, PL | 1 |
| Allen, LM; Wolfe, RG | 1 |
| Amar, A; Bekierkunst, A; Flechner, I | 1 |
| Champney, WS; Jensen, RA | 1 |
| Galley, WC; Purkey, RM | 1 |
| Braidman, IP; Rose, DP | 1 |
| D'Alessio, G; Josse, J | 1 |
| Wolf, H | 1 |
| Dornand, J; Mani, JC; Mousseron-Canet, M; Vial-Reveillon, F | 1 |
| Shigehisa, S; Shimoyama, M; Ueda, I | 1 |
| Allison, WS; Connors, MJ; White, HB | 1 |
| Brand, L; Heitz, JR | 1 |
| Brown, RR; Wolf, H | 1 |
| Cole, KW; Gaertner, FH; Welch, GR | 1 |
| Jacobson, KB; Knopp, JA | 1 |
| Barry, RE; Corcoran, D; Strittmatter, P | 1 |
| Bruice, TC; Kasperek, GJ; Main, L | 1 |
| Myer, YP; Pal, PK | 1 |
| Brown, RR; Hankes, LV; Jansen, CR; Leklem, J; Mekel, RC | 1 |
| Scholz, G; Streffer, C | 1 |
| Mauron, J; Mottu, F; Spohr, G | 1 |
| Scott, MD; Sykes, BD | 1 |
| Audette, RC; Purvis, JL; Worthen, LR; Youngken, HW | 1 |
| v Muiswinkel-Voetberg, H; Veeger, C | 1 |
| Coleman, PL; Weiner, H | 1 |
| Grunicke, H; Keller, J; Liersch, M | 1 |
| Baici, A; Karlovic, D; Luisi, PL; Olomucki, A | 1 |
| Frith, LO; Kirsch, RE; Saunders, SJ; Stead, RH | 1 |
| Danson, MJ; Weitzman, PD | 1 |
| Camerman, A; Deranleau, DA; Herriott, JR | 1 |
| Pizer, LI; Winicov, I | 1 |
| Jörnvall, H; Koberstein, R; Noack, K; Rasched, I; Sund, H; Witzemann, V | 1 |
| Imamura, A; Nagata, C; Umeyama, H | 1 |
| Gross, D | 1 |
| Haljasmaa, O; Ross, SB | 1 |
| Cho-Chung, YS; Pitot, HC | 1 |
| DeMoss, RD; Jean, M | 1 |
| Ceauşi, G; Dumitrescu, C | 1 |
| Gholson, RK | 1 |
| Greengard, P; Kalinsky, H; Manning, TJ; Zak, SB | 1 |
| Masana, Y; Nakagawa, I; Suzuki, T; Takahashi, T | 1 |
| Sourkes, TL | 1 |
| Teuscher, G | 1 |
| Friedrich, B; Schlegel, HG | 1 |
| Brody, S | 1 |
| Ohguri, S | 1 |
| Henderson, M; Kitos, PA | 1 |
| Motooka, K; Murata, K; Shibata, K | 1 |
| Bender, DA; Magboul, BI; Wynick, D | 1 |
| Fujii, K; Imai, H; Nasu, S; Sakakibara, S; Ueda, I; Yamaguchi, K | 1 |
| Sano, K; Shin, M; Umezawa, C | 2 |
| Bender, DA; Totoe, L | 1 |
| Vekshin, NL | 2 |
| Davis, JM; Maki, AH | 1 |
| Hayakawa, T; Iwai, K | 1 |
| Imai, H; Nasu, S; Sakakibara, S; Ueda, I; Yamaguchi, K | 1 |
| Abu El Failat, RR; Davies, JV; Moore, JS | 1 |
| Sano, K; Shin, M; Umezawa, C; Yamada, O | 1 |
| Babu, P; Siddiqui, SS | 1 |
| Sauberlich, HE | 1 |
| Brand, L; Ross, JB; Schmidt, CJ | 1 |
| Eftink, MR; Selvidge, LA | 1 |
| Marquardt, RR; Park, IK | 1 |
| Iwai, K; Motooka, K; Murata, K; Shibata, K | 2 |
| Badawy, AA; Evans, CM; Evans, M; Punjani, NF | 1 |
| Arend, RA; Brown, RR; Walter, S; Wolf, H | 1 |
| Arend, RA; Brown, RR; Wolf, H | 1 |
| Ritzmann, RF; Tabakoff, B | 1 |
| Ishizaki, T; Morii, N; Narumiya, S; Nemoto, Y; Saito, Y; Watanabe, N | 1 |
| Bhaduri, A; Mukherji, S; Ray, S | 1 |
| Kacser, H; Small, JR | 1 |
| Blanke, SR; Collier, RJ; Reich, KA; Wilson, BA | 1 |
| Driscoll, ER; Jackson, TM; Kirkland, JB; Rawling, JM | 1 |
| Baker, DH; Oduho, GW | 1 |
| Henning, SM; Swendseid, ME; Zhang, JZ | 1 |
| Borchardt, RT; Rawitch, A; Squier, TC; Yeh, J; Yuan, CS | 1 |
| Bhattacharyya, A; Bhattacharyya, B; Roy, S | 1 |
| Li, J; Liang, SJ; Lin, ZJ; Song, SY; Tsou, CL; Yang, J; Zhang, FM | 1 |
| Dame, AJ; Jacobson, EL; Jacobson, MK; Pyrek, JS | 1 |
| Jackson, TM; Kirkland, JB; Poirier, GG; Rawling, JM; Roebuck, BD | 1 |
| Bizouarn, T; Cotton, NP; Diggle, C; Grimley, RL; Jackson, JB; Quirk, PG; Thomas, CM | 1 |
| Bizouarn, T; Cotton, NP; Diggle, C; Grimley, RI; Jackson, JB; Quirk, PG; Thomas, CM | 1 |
| Fujita, Y; Kimura, A; Mori, Y; Sano, K; Shin, M; Umezawa, C; Yoshida, K | 1 |
| Branlant, G; Gabellieri, E; Rahuel-Clermont, S; Strambini, GB | 1 |
| Beattie, BK; Merrill, AR; Prentice, GA | 1 |
| Kondo, T; Marugami, M; Shibata, K; Umezawa, C | 1 |
| de Murcia, G; Jacobson, MK; Kim, H; Ménissier-de Murcia, J; Reinbolt, J; Rolli, V; Ruf, A; Schulz, G; Simonin, F | 1 |
| Bisswanger, H; Hennig, J; Hübner, G; Kern, G; Neef, H; Spinka, M | 1 |
| Gupta, GS; Kang, BP | 1 |
| Hashimoto, C; Nakakita, S; Sano, K; Shin, M; Umezawa, C | 1 |
| Bahnson, BJ; Chin, JK; Colby, TD; Goldstein, BM; Klinman, JP | 1 |
| Blinder, KL; Moffett, JR; Namboodiri, MA; Venkateshan, CN | 1 |
| Bertoloni, G; Jori, G; Polo, L; Presti, F; Schindl, A; Schindl, L | 1 |
| Beattie, BK; Merrill, AR | 1 |
| Ma, H; Penning, TM; Ratnam, K | 1 |
| Iguchi, S; Ohnishi, M; Sano, K; Shin, M; Umezawa, C | 1 |
| Gathof, BS; Jacomelli, G; Manzoni, F; Micheli, V; Peruzzi, L; Pompucci, G; Rocchigiani, M; Sestini, S; Zammarchi, E | 1 |
| Cotton, NP; Jackson, JB; Peake, SJ; Venning, JD | 1 |
| Grant, RS; Kapoor, V; Matanovic, G; Passey, R; Smythe, G | 1 |
| Murray, MF | 1 |
| Digits, JA; Hedstrom, L | 1 |
| Hölzer, M; van Pée, KH | 1 |
| Park, MH; Wolff, EC; Wolff, J | 1 |
| Jackson, JB; Peake, SJ; Quirk, PG; Venning, JD | 1 |
| Espinosa, M; Grant, RS; Kapoor, V; Naif, H | 1 |
| Brown, OR; Dale, WE; Dang, Y | 1 |
| Feyereisen, R; Murataliev, MB | 1 |
| Yankovsky, NK; Zdanovskaia, MV; Zdanovsky, AG | 1 |
| Doehr, O; Gutierrez, A; Paine, M; Roberts, GC; Scrutton, NS; Wolf, CR | 1 |
| Fukuwatari, T; Shibata, K; Sugimoto, E | 3 |
| Fukuwatari, T; Fushiki, T; Ishihara, K; Shibata, K; Sugimoto, E | 1 |
| Merrill, AR; Mohammadi, F; Prentice, GA | 1 |
| Fukuwatari, T; Hayakawa, F; Morikawa, Y; Shibata, K; Sugimoto, E | 1 |
| He, XY; Lin, D; Mehta, P; Merz, G; Schulz, H; Wen, GY; Yang, SY; Yang, YZ | 1 |
| Fukuwatari, T; Shibata, K; Sugimoto, E; Suzuki, Y | 1 |
| Bécam, AM; Herbert, CJ; Kucharczyka, R; Nawara, M; Panozzo, C; Rytka, J; Skoneczny, M; Suski, C | 1 |
| Fukuwatari, T; Morikawa, Y; Shibata, K; Sugimoto, E | 1 |
| Baran, H; Draxler, M; Kepplinger, B; Nohl, H; Staniek, K; Stur, J | 1 |
| Chiarugi, A; Dello Sbarba, P; Moroni, F; Rovida, E | 1 |
| Andris, F; Leo, O; Rongvaux, A; Van Gool, F | 1 |
| Moffett, JR; Namboodiri, MA | 1 |
| Birdsong, WT; Fjeld, CC; Goodman, RH | 1 |
| Grant, R; Kapoor, V | 1 |
| Broos, J; Gabellieri, E; Jackson, JB; Strambini, GB; van Boxel, GI | 1 |
| ALIVISATOS, SG | 1 |
| REMILY, C; WOLFE, RG | 1 |
| BERRY, LJ; SMYTHE, DS | 1 |
| GIBSON, F; GIBSON, MI; MORGAN, PN | 1 |
| KIMURA, S; MIKUNI, M; TAKESHIMA, M | 1 |
| CONTRERAS, E; CROXATTO, R; HUIDOBRO, F | 1 |
| HJELT, L; LAHIKAINEN, T; OHMAN, S; VISAKORPI, JK | 1 |
| IMSANDE, J | 1 |
| KAPLAN, NO; MCKAY, RH | 1 |
| BROWN, FC | 1 |
| Harper, AE; Savage, JR | 1 |
| FRATTA, I; GREENGARD, P; SIGG, EB; ZAK, SB | 1 |
| CHATTERJEE, SK; GAL, EM; MARSHALL, FD | 1 |
| HATANAKA, M; HAYAISHI, O; KUNO, S; KURIHARA, N; NAKAJIMA, M; TANIUCHI, H | 1 |
| GREENGARD, P; QUINN, GP; REID, MB | 1 |
| HAYAISHI, O; NAKAMURA, S; NISHIZUKA, Y | 1 |
| GHOLSON, RK; HAYAISHI, O; ICHIYAMA, A; NISHIZUKA, Y | 1 |
| HAYAISHI, O; HONJO, T; ICHIYAMA, A; KAWAI, H; NAKAMURA, S; NISHIZUKA, Y; SENOH, S | 1 |
| HAYAISHI, O; ICHIYAMA, A; IKEDA, M; NAKAMURA, S; NISHIZUKA, Y; TSUJI, H | 1 |
| Boulla, G; Deterre, P; Lacapère, JJ; Lund, FE; Oppenheimer, N; Primack, J; Schuber, F | 1 |
| Anantha, S; Begley, TP; Colabroy, K; Gerdes, S; Goral, V; Kurnasov, O; Osterman, A | 1 |
| Fukuwatari, T; Sasaki, R; Shibata, K; Wada, H | 1 |
| Okamoto, H | 1 |
| Ohnishi, M; Sano, K; Shin, M; Umezawa, C | 1 |
| Fukuoka, S; Fukuwatari, T; Ohsaki, S; Sasaki, R; Shibata, K; Suzuki, Y | 1 |
| Chandy, M; Gifford, DK; Hannett, NM; Pokholok, DK; Rinaldi, NJ; Robert, F; Rolfe, A; Workman, JL; Young, RA | 1 |
| Connor, SC; Delaney, J; Haselden, JN; Hodson, MP; Holder, JC; Hutton, KA; Kenny, SP; McGill, PJ; Sweatman, BC; Thakkar, H; Waterfield, CJ | 1 |
| Fukuwatari, T; Kimtjra, N; Ohta, M; Sasaki, R; Shibata, K | 1 |
| van der Donk, WA; Woodyer, R; Zhao, H | 1 |
| Cai, RX; Wang, H; Wang, J; Xu, J | 1 |
| Egashira, Y; Nagaki, S; Sanada, H | 1 |
| Gonzalez, FJ; Inoue, Y; Kim, I; Kimura, S; Shin, M | 1 |
| Egashira, Y; Sanada, H; Sato, M; Shin, M; Sugawara, R; Tanabe, A | 1 |
| Kirkland, JB; Thorn, SL; Young, GS | 1 |
| Forouhar, F; Khan, JA; Tao, X; Tong, L | 1 |
| Darlington, LG; Forrest, CM; Mackay, GM; Stone, TW; Stoy, N | 1 |
| Kujundzić, RN; Lowenthal, JW | 1 |
| Engel, PC; Hamza, MA | 1 |
| Herman, P; Vecer, J | 1 |
| Boubellouta, T; Dufour, E; Leriche, F; Tourkya, B | 1 |
| Li, D; Qu, JY; Zheng, W | 2 |
| Fukuwatari, T; Okuno, A; Shibata, K; Takahashi, K | 1 |
| Sevrioukova, IF | 1 |
| Esposito, L; Pennacchio, A; Raia, CA; Rossi, M; Zagari, A | 1 |
| Fülöp, F; Klivényi, P; Toldi, J; Vámos, E; Vécsei, L; Zádori, D | 1 |
| Feng, YL; Liao, X; Poon, R; Rubab, M; Zhu, J | 1 |
| Domanska, G; Fusch, G; Gruendling, M; Haas, JP; Holtfreter, B; Reinke, P; Schefold, JC; Schuett, C; Westerholt, A; Zeden, JP | 1 |
| Demos, SG; Lin, B; Matthews, DL; Saroufeem, RM; Urayama, S | 1 |
| Alfano, RR; Pu, Y; Savage, HE; Schantz, SP; Tang, GC; Wang, WB | 1 |
| Gustafsson, FS; Meints, CE; Scrutton, NS; Wolthers, KR | 1 |
| Král, V; Petkova, GA; Záruba, K | 1 |
| Alfano, RR; Ebenezar, J; Liu, CH; Pu, Y; Wang, WB | 1 |
| Alfano, RR; Pu, Y; Wang, W; Yang, Y | 1 |
| Callender, R; Deng, H; Desamero, R; Nie, B | 1 |
| Li, D; Li, S; Qu, JY; Teh, SK; Yang, Y; Zeng, Y; Zheng, W | 1 |
| Arabi, H; Bahari, A; Karimi, F; Karimi-Maleh, H; Moradi, R; Sadeghi, R; Sebt, SA | 1 |
| Adams, S; Ahrendt, T; Bode, HB; Guillemin, GJ; Oezen, I; Opitz, CA; Platten, M; Radlwimmer, B; Sahm, F; von Deimling, A; Wick, W | 1 |
| Jyothikumar, V; Periasamy, A; Sun, Y | 1 |
| Oxenkrug, G | 1 |
| Egashira, Y; Gomi, RT; Hirai, S; Matsuda, H | 1 |
| Achilefu, S; Ackerstaff, E; Alfano, RR; Gu, Y; Koutcher, JA; Pu, Y; Tang, R; Wang, W; Xu, B; Xue, J | 1 |
| Lundblad, JR; Madison, DL; Siess, D; Wirz, JA | 1 |
| Fukuwatari, T; Morita, N; Shibata, K; Shibata, Y | 1 |
| Doi, K; Mutaguchi, Y; Ogura, R; Ohshima, T; Wakamatsu, T | 1 |
| Egashira, Y; Hirai, S; Koshiguchi, M; Matsuda, H; Sato, M; Yakushiji, M | 1 |
| Alsaeed, AH; AlSalhi, MS; Devanesan, S; Ganesh, KM; Masilamani, V; Palled, S; Perinbam, K; Prasad, S; Ravikumar, M | 1 |
| Alfano, RR; Budansky, Y; Pu, Y; Sordillo, LA; Sordillo, PP | 1 |
| Braidy, N; Bustamante, S; Grant, R; Guillemin, GJ; Lovejoy, D; Sheipouri, D | 1 |
| Bertuch, AA; Polleys, EJ | 1 |
| Badawy, AA; Moffett, JR; Namboodiri, AM | 1 |
| Cheng, X; Hao, H; Li, Q; Liu, F; Liu, H; Wang, G; Wang, H; Xing, R; Ye, H; Zhao, M | 1 |
| James, EL; Karoly, ED; Lane, JA; Michalek, RD; Parkinson, EK | 1 |
| Hanna-Rose, W; Holleran, LM; McReynolds, MR; Wang, W | 1 |
| Alfano, RR; Harvey, G; Harvey, T; Lu, L; Rodríguez-Contreras, A; Shi, L | 1 |
| Essen, LO; Geisselbrecht, Y; Ignatz, E; Kiontke, S | 1 |
| Baur, JA; Chellappa, K; Frederick, DW; Hui, S; Krukenberg, K; Liu, L; Migaud, M; Mitchison, TJ; Quinn, WJ; Rabinowitz, JD; Redpath, P; Su, X; White, E; Zhan, L | 1 |
| AlSalhi, MS; Atif, M; Devanesan, S; Farhat, K; Masilamani, V; Rabah, D | 1 |
| Chen, C; Hanson, AR; Kerr, BJ; Saqui-Salces, M; Shurson, GC; Urriola, PE; Wang, L; Yao, D | 1 |
| Bauche, A; Fliegert, R; Guse, AH; Harneit, A; Kulow, F; Rosche, A; Wolters, V | 1 |
| Andreasson, KI; Bernstein, D; Contrepois, K; Coronado, M; Dove, C; Joshi, AU; Lee, BA; Liu, L; Majeti, R; Mhatre, S; Migaud, M; Minhas, PS; Mochly-Rosen, D; Moon, PK; Rabinowitz, JD; Snyder, MP; Wang, Q | 1 |
| Cao, R; Periasamy, A; Rehman Alam, S; Siller, K; Wallrabe, H | 1 |
| Periasamy, A | 1 |
| Adanyeguh, I; Collins, B; Durr, A; Evans, RM; Fan, W; Ichou, F; Kinoshita, C; La Spada, AR; Mochel, F; Morrison, RS; Muotri, AR; Niu, C; Sopher, BL; Stoyas, CA; Switonski, PM; Wall, CE; Ward, JM | 1 |
| Savitz, J | 1 |
| Kibi, M; Kobayashi, T; Kodama, Y; Nishiumi, S; Yoshida, M | 1 |
| Audrito, V; Deaglio, S; Gaudino, F; Managò, A; Messana, VG; Raffaelli, N; Sorci, L | 1 |
| Berge, RK; Bjørndal, B; Lindquist, C; Lund, A; Nygård, O; Skorve, J; Slettom, G; Svardal, A | 1 |
| Castro-Portuguez, R; Sutphin, GL | 1 |
| Arun, P; Badawy, AA; Ives, JA; Moffett, JR; Namboodiri, AM; Puthillathu, N; Vengilote, R | 1 |
| Chakraborty, A; Chatterjee, SK; Dasgupta, AK | 1 |
| Altman, RA; Borel, T; Davis, I; de Azambuja, F; Johnson, D; Liu, A; Sorrentino, JP; Udokwu, C; Yang, Y | 1 |
| Gao, X; Pu, Y; Smith, J; Wang, C; Wu, B; Xue, J | 1 |
| Bruls, YMH; Connell, NJ; de Vogel, J; Fealy, CE; Geurts, J; Grevendonk, L; Hageman, R; Havekes, B; Hoeks, J; Houtkooper, RH; Moonen-Kornips, E; Schrauwen, P; Schrauwen-Hinderling, VB; Zapata-Perez, R | 1 |
| Lednev, IK; Weber, A; Wójtowicz, A | 1 |
| An, SY; Bohney, S; Bommi, PV; Calcutt, MW; Chandel, NS; Gao, P; Gibbs, B; Huang, S; Kapitsinou, PP; Kavanaugh, MA; Kerr, EW; Leonardi, R; Rajendran, G; Schonfeld, M; Tiwari, R; Torosyan, R; Truax, AD | 1 |
| Anglicheau, D; Bignon, Y; Cippà, PE; Fohlen, B; Galichon, P; Hertig, A; Karras, A; Lenoir, O; Nadour, Z; Naesens, M; Nemazanyy, I; Pallet, N; Poindessous, V; Rinaldi, A; Weill-Raynal, P | 1 |
| Battaglia, S; Cheever, MA; Chiello, J; Chodon, T; D'Amico, L; Danaher, P; Dennis, L; Disis, ML; Fling, SP; Geller, MA; Gunawan, R; Hutson, A; Kaiser, JC; Koya, R; Lacroix, AM; Lele, S; Liu, S; Lugade, AA; Mager, DE; Matsuzaki, J; McGray, AJR; Morishima, C; Morrison, CD; Nguyen, VA; Odunsi, K; Putluri, N; Putluri, V; Qian, F; Ramchurren, N; Ravi, S; Rosario, S; Tsuji, T; Warren, S; Yu, H; Zha, W; Zsiros, E | 1 |
| Boos, D; Chuang, TD; Khorram, O; Quintanilla, D | 1 |
| Elliott, MA; Nanga, RPR; Reddy, R; Soni, ND; Swago, S; Swain, A; Wilson, N; Witschey, WR | 1 |
| Burdett, H; Damaraju, N; DiAntonio, A; Eastman, S; Grant, M; Gu, W; Guo, M; Hancock, SJ; Hartley-Tassell, L; Kargios, N; Kobe, B; Landsberg, MJ; Li, S; Lim, BYJ; Manik, MK; Maruta, N; Masic, V; Milbrandt, J; Mosaiab, T; Nanson, JD; Prokes, I; Schembri, MA; Shi, Y; Smith, TG; Song, L; Vasquez, E; Ve, T; Weagley, JS; Zaydman, MA | 1 |
| Barr, DB; Batross, J; Baumert, BO; D'Souza, P; Fiedler, N; Kaewthit, K; Kohsuwan, K; Liang, D; Mangklabruks, A; Naksen, W; Panuwet, P; Pingwong, S; Prapamontol, T; Promkam, N; Ryan, PB; Sittiwang, S; Suttiwan, P; Tan, Y; Yakimavets, V | 1 |
| Liu, Q; Liu, R; Lu, Q; Pu, Y; Wang, S; Yin, L; Yu, X; Zhang, H; Zhang, Y; Zhao, C; Zhou, J | 1 |
| Ejtemaei-Mehr, S; Ghahremani, MH; Ghanbari, A; Ghazi-Khansari, M; Guillemin, GJ; Jand, Y | 1 |
| Fan, X; Li, L; Sun, P; Wang, J; Xu, Q; Yu, Y; Yu, Z; Zhang, Z | 1 |
| Chailyan, SG; Danielyan, KE; Ginosyan, SV; Grabski, HV; Tiratsuyan, SG | 1 |
| Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S | 1 |
| Bozon, K; Bröer, S; Cuny, H; Dunwoodie, SL; Kirk, RB; Sheng, DZ | 1 |
| Bakker, BM; Bandsma, RHJ; Bourdon, C; Calon, MM; Chi, L; Furse, S; Gonzales, GB; Hu, G; Kim, PK; Koulman, A; Lee, D; Ling, C; Swann, JR; Thind, MK; Versloot, CJ | 1 |
| Bolaños-Jiménez, F; Croyal, M; García Santillán, JA; Gourdel, M; Mezo-González, CE; Reyes-Castro, LA | 1 |
| Aggarwal, S; Bedi, O; Maiwall, R; Maras, JS; Pamecha, V; Ramakrishna, G; Rastogi, A; Trehanpati, N; Yadav, V | 1 |
| Arslan, AA; Behndig, AF; Brennan, P; Cai, Q; Chen, C; Chen, Y; Fanidi, A; Freedman, ND; Gaziano, JM; Giles, GG; Huang, WY; Johansson, M; Koh, WP; Langhammer, A; Le Marchand, L; Manjer, J; Meyer, K; Midttun, Ø; Prentice, R; Robbins, HA; Sandsveden, M; Sesso, HD; Shu, XO; Stevens, VL; Sørgjerd, EP; Ueland, PM; Ulvik, A; Visvanathan, K; Wang, Y; Weinstein, SJ; Yuan, JM; Zahed, H; Zhang, X; Zheng, W | 1 |
| Barberis, E; Bleve, A; Bombace, S; Bottazzi, B; Condorelli, G; Consonni, FM; Durante, B; Garlatti, V; Manfredi, M; Marengo, E; My, I; Pandolfo, C; Sica, A; Torri, V; Vanella, VV | 1 |
| Elliott, MA; Nanga, RPR; Reddy, R; Swago, S; Swain, A; Wilson, NE; Witschey, WR | 1 |
| Ciampa, EJ; Clark, AJ; Etzrodt, V; Flores, BM; Huang, H; Parikh, SM; Saade, MC; Takakura, A; Vemireddy, V; Vu, KQ; Zandi-Nejad, K; Zsengellér, ZK | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
25 review(s) available for nad and tryptophan
| Article | Year |
|---|---|
The functions and regulation of tryptophan pyrrolase.
Topics: Allosteric Regulation; Aminolevulinic Acid; Animals; Dactinomycin; Feedback; Gluconeogenesis; Heme; Kinetics; Kynurenine; Liver; NAD; NADP; Rats; Tryptophan; Tryptophan Oxygenase | 1977 |
Circular polarization of luminescence: biochemical and biophysical applications.
Topics: Acridines; Amino Acids; Antibodies; Antigen-Antibody Reactions; Binding Sites; Biopolymers; Chlorophyll; Chymotrypsin; Coloring Agents; Conalbumin; Dipeptides; Europium; Lasalocid; Luminescent Measurements; Models, Biological; Molecular Conformation; NAD; Optical Rotation; Oxidoreductases; Phosphorylases; Proteins; Spectrum Analysis; Terbium; Transferrin; Tryptophan | 1978 |
Comparison of tryptophan metabolism in vivo and in isolated hepatocytes from vitamin B6 deficient mice.
Topics: Adrenalectomy; Adult; Animals; Cells, Cultured; Child; Female; Humans; Hydrolases; Kinetics; Kynurenine; Kynurenine 3-Monooxygenase; Liver; Male; Mice; Middle Aged; Mixed Function Oxygenases; NAD; Ovariectomy; Oxidation-Reduction; Rats; Tryptophan; Tryptophan Oxygenase; Vitamin B 6 Deficiency | 1991 |
Nicotinamide deficiency and adrenocortical steroids.
Topics: Adrenal Cortex Hormones; Animals; Deficiency Diseases; Dogs; Female; Liver; NAD; Rats; Tryptophan | 1968 |
Excretion of tryptophan metabolites as affected by pregnancy, contraceptive steroids, and steroid hormones.
Topics: Androsterone; Animals; Contraceptives, Oral; Enzyme Induction; Estradiol; Female; Humans; Hydrocortisone; Kynurenine; Liver; Male; Megestrol; NAD; Niacinamide; ortho-Aminobenzoates; Pregnancy; Pyridoxine; Rats; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1971 |
Long-range nonradiative transfer of electronic excitation energy in proteins and polypeptides.
Topics: Adrenocorticotropic Hormone; Catalase; Chemical Phenomena; Chemistry, Physical; Coloring Agents; Copper; Dipeptides; Energy Transfer; Fluorescence; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Hemoglobins; Indoles; Insulin; L-Lactate Dehydrogenase; Mathematics; Monoiodotyrosine; Myoglobin; NAD; Parathyroid Hormone; Peptides; Phenols; Phenylalanine; Phosphoric Acids; Picolines; Plant Proteins; Proteins; Pyridoxal Phosphate; Thyroxine; Transferrin; Tryptophan; Tyrosine | 1971 |
Nuclear magnetic resonance studies of the dynamic aspects of molecular structure and interaction in biological systems.
Topics: Aspartate Carbamoyltransferase; Aspirin; Chymotrypsin; Histidine; Ligands; Macromolecular Substances; Magnetic Resonance Spectroscopy; Muramidase; NAD; Penicillin G; Peptides; Protein Binding; Protein Conformation; Protein Denaturation; Ribonucleases; Serum Albumin; Staphylococcus; Sulfonamides; Tryptophan; Valinomycin | 1972 |
[Naturally occurring material containing pyridine and its biosynthesis].
Topics: Alkaloids; Bacteria; Carbon Radioisotopes; Isomerism; Molecular Conformation; NAD; Niacinamide; Nicotinic Acids; Oxygen Consumption; Picolinic Acids; Plants; Pyridines; Species Specificity; Streptomyces; Structure-Activity Relationship; Terpenes; Tryptophan | 1970 |
[Physiopathology of the nutritional imbalance caused by deficiency of vitamin PP].
Topics: Amino Acids; Animals; Avitaminosis; Humans; NAD; NADP; Niacinamide; Pellagra; Tryptophan | 1968 |
Interactions of thiamin, riboflavin, and other B-vitamins.
Topics: Adult; Animals; Ascorbic Acid; Aspartate Aminotransferases; Biotin; Cricetinae; Female; Humans; Male; NAD; Nicotinic Acids; Pantothenic Acid; Pyridoxine; Riboflavin; Riboflavin Deficiency; Thiamine; Tryptophan; Vitamin B 12; Vitamin B 6 Deficiency; Vitamin B Complex | 1980 |
Evaluating the role of niacin in human carcinogenesis.
Topics: Anticarcinogenic Agents; Diet; Erythrocytes; Humans; NAD; Niacin; Niacinamide; Poly Adenosine Diphosphate Ribose; Tryptophan | 1995 |
Tryptophan and niacin nutrition--is there a problem?
Topics: Adult; Animals; Cognition Disorders; Environmental Exposure; Humans; Hydrolases; Iron Deficiencies; Kynurenine 3-Monooxygenase; Lead Poisoning; Liver; Mixed Function Oxygenases; NAD; NADP; Neoplasms; Niacin; Nutritional Requirements; Oxidative Stress; Trace Elements; Tryptophan; Zinc | 1996 |
Reconstructing eukaryotic NAD metabolism.
Topics: Adenosine Diphosphate Ribose; Animals; Eukaryotic Cells; Humans; NAD; Tryptophan | 2003 |
Tryptophan and the immune response.
Topics: Animals; Dendritic Cells; Dioxygenases; Humans; Immune System; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; NAD; Oxygenases; Poly(ADP-ribose) Polymerases; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase | 2003 |
Recent advances in physiological and pathological significance of tryptophan-NAD+ metabolites: lessons from insulin-producing pancreatic beta-cells.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Cyclic ADP-Ribose; Diabetes Mellitus, Experimental; DNA Repair; Humans; Insulin; Islets of Langerhans; Membrane Glycoproteins; Models, Biological; NAD; Poly Adenosine Diphosphate Ribose; Signal Transduction; Tryptophan | 2003 |
Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery.
Topics: Acrylamides; Adenosine Diphosphate Ribose; Aging; Animals; Antineoplastic Agents; Autoimmune Diseases; Clinical Trials, Phase II as Topic; Cyclic ADP-Ribose; DNA Damage; Drug Design; Enzyme Inhibitors; Humans; Kynurenine; Mice; NAD; Neoplasms; Neurodegenerative Diseases; Neuroprotective Agents; Piperidines; Poly Adenosine Diphosphate Ribose; Signal Transduction; Sirtuins; Tryptophan | 2007 |
Tryptophan, adenosine, neurodegeneration and neuroprotection.
Topics: Adenosine; Animals; Hepatic Encephalopathy; Humans; Kynurenine; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Tryptophan | 2007 |
Frequency domain fluorometry with pulsed light-emitting diodes.
Topics: Acrylamide; Computers; Equipment Design; Fluorescence Polarization; Fluorometry; Lasers; Light; NAD; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Tryptophan | 2008 |
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies.
Topics: Animals; Brain; Glutamic Acid; Humans; Kynurenic Acid; Mitochondrial Diseases; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolinic Acid; Tryptophan | 2009 |
Insulin resistance and dysregulation of tryptophan-kynurenine and kynurenine-nicotinamide adenine dinucleotide metabolic pathways.
Topics: Biomarkers; Humans; Insulin Resistance; Kynurenine; Metabolic Networks and Pathways; NAD; Tryptophan | 2013 |
The end of the road for the tryptophan depletion concept in pregnancy and infection.
Topics: Antigen-Presenting Cells; Communicable Diseases; Female; Fetus; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; NAD; Oxidative Stress; Pregnancy; Pregnancy Complications; Protein Binding; T-Lymphocytes; Tryptophan; Tryptophan Oxygenase | 2016 |
The kynurenine pathway: a finger in every pie.
Topics: Aging; Animals; Energy Metabolism; Humans; Kynurenine; Mental Disorders; NAD; Neurodegenerative Diseases; Signal Transduction; Tryptophan | 2020 |
NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer.
Topics: Biosynthetic Pathways; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Humans; Immunity, Cellular; Immunity, Innate; NAD; Neoplasms; Sirtuins; Tryptophan; Tumor Microenvironment | 2019 |
Kynurenine pathway, NAD
Topics: Aging; Animals; Brain; Humans; Kynurenine; Longevity; Metabolic Networks and Pathways; Mice; Mitochondria; Mitophagy; NAD; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Tryptophan | 2020 |
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan | 2022 |
1 trial(s) available for nad and tryptophan
| Article | Year |
|---|---|
NAD+-Precursor Supplementation With L-Tryptophan, Nicotinic Acid, and Nicotinamide Does Not Affect Mitochondrial Function or Skeletal Muscle Function in Physically Compromised Older Adults.
Topics: Aged; Dietary Supplements; Female; Humans; Male; Mitochondria; Muscle, Skeletal; NAD; Niacin; Niacinamide; Tryptophan | 2021 |
328 other study(ies) available for nad and tryptophan
| Article | Year |
|---|---|
Regulation of Chorismate mutase-prephenate dehydratase and prephenate dehydrogenase from alcaligenes eutrophus.
Topics: Alcaligenes; Cell-Free System; Chorismate Mutase; Enzyme Activation; Feedback; Hydro-Lyases; Hydrogen-Ion Concentration; Isomerases; NAD; Oxidoreductases; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Pyruvates; Temperature; Tryptophan; Tyrosine | 1976 |
Studies on the rate of incorporation of tryptophan into nicotinamide-adenine dinucleotides in rats chronically exposed to carbon disulphide.
Topics: Animals; Carbon Disulfide; Kinetics; Liver; NAD; NADP; Rats; Tryptophan | 1976 |
Tryptophan metabolism in baboons: effect of riboflavin and pyridoxine deficiency.
Topics: 11-Hydroxycorticosteroids; Animals; Erythrocytes; Haplorhini; Kynurenine; Male; NAD; NADP; Papio; Riboflavin Deficiency; Tryptophan; Vitamin B 6 Deficiency | 1975 |
On the regulation of tryptophan metabolism "via" kynurenine.
Topics: Animals; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Hydroxylation; Kynurenine; Mixed Function Oxygenases; NAD; NADP; Nicotinic Acids; ortho-Aminobenzoates; Phenylalanine; Rats; Serotonin; Solubility; Tryptophan; Xanthurenates | 1978 |
Prevention by pyrazole of the effects of chronic ethanol administration on the redox states of the hepatic nicotinamide--adenine dinucleotide (phosphate) couples and on liver and brain tryptophan metabolism in the rat.
Topics: Animals; Brain; Ethanol; Liver; Male; NAD; NADP; Oxidation-Reduction; Pyrazoles; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase | 1979 |
Kynurenine formamidase inhibition as a possible mechanism for certain teratogenic effects of organophosphorus and methylcarbamate insecticides in chicken embryos.
Topics: Amidohydrolases; Animals; Arylformamidase; Carbamates; Chick Embryo; Chickens; In Vitro Techniques; Insecticides; Kynurenine; Liver; Male; Mice; NAD; Organophosphorus Compounds; Structure-Activity Relationship; Teratogens; Tryptophan; Tryptophan Oxygenase | 1977 |
Further studies on the metabolism of tryptophan in Trypanosoma brucei gambiense: cofactors, inhibitors, and end-products.
Topics: Acetates; Carbon Radioisotopes; Chromatography; Enzyme Inhibitors; Indoles; Ketoglutaric Acids; Lactates; NAD; Pyridoxal Phosphate; Trypanosoma brucei gambiense; Tryptophan | 1975 |
Coenzyme interaction with horse liver alcohol dehydrogenase. Evidence for allosteric coenzyme binding sites from thermodynamic equilibrium studies.
Topics: Alcohol Oxidoreductases; Allosteric Site; Animals; Dialysis; Horses; Liver; Molecular Weight; NAD; Protein Binding; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 1975 |
Kynureninase-Type enzymes of Penicillum roqueforti, Aspergillus niger, Rhizopus stolonifer, and Pseudomonas fluorescens: further evidence for distinct kynureninase and hydroxykynureninase activities.
Topics: Ammonium Sulfate; Aspergillus; Cell Fractionation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Induction; Hydrolases; Hydroxylation; Kynurenine; NAD; ortho-Aminobenzoates; Penicillium; Protamines; Pseudomonas fluorescens; Rhizopus; Species Specificity; Tryptophan | 1975 |
On the role of tryptophan residues in the mechanism of action of glyceraldehyde-3phosphate dehydrogenase as tested by specific modification.
Topics: Apoproteins; Benzyl Compounds; Binding Sites; Chromatography, Gel; Chymotrypsin; Dialysis; Electrophoresis, Disc; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; NAD; Nitro Compounds; Protein Binding; Saccharomyces cerevisiae; Sulfhydryl Compounds; Sulfonium Compounds; Trypsin; Tryptophan | 1975 |
NAD precursors as antiteratogens against aminothiadiazole.
Topics: Animals; Dose-Response Relationship, Drug; Female; Fetal Resorption; Gestational Age; Kynurenine; Male; NAD; Niacinamide; Nicotinic Acids; Pregnancy; Quinolinic Acids; Rats; Teratogens; Thiadiazoles; Tryptophan | 1976 |
Kynureninase-type enzymes and the evolution of the aerobic tryptophan-to-nicotinamide adenine dinucleotide pathway.
Topics: Animals; Anura; Biological Evolution; Chickens; Fungi; Hydrolases; Kynurenine; Liver; Mice; NAD; Pseudomonas fluorescens; Species Specificity; Trout; Tryptophan; Turtles; Xanthomonas | 1977 |
Effect of dietary protein level on some key enzymes of the tryptophan-NAD pathway.
Topics: Animals; Dietary Proteins; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kidney; Liver; NAD; Nicotinic Acids; Pentosyltransferases; Quinolinic Acids; Rats; Tryptophan; Tryptophan Oxygenase | 1977 |
Effect of diet restriction on some key enzymes tryptophan-NAD pathway in rats.
Topics: Animals; Carboxy-Lyases; Dietary Proteins; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Liver; Male; NAD; Nicotinamide Mononucleotide; Nicotinic Acids; Nutrition Disorders; Pentosephosphates; Pentosyltransferases; Picolinic Acids; Quinolinic Acids; Rats; Tryptophan; Tryptophan Oxygenase | 1977 |
The reaction of protein tryptophanyl residues with reduced nicotinamide adenine dinucleotide. Structure of a model adduct.
Topics: Alcohol Oxidoreductases; Binding Sites; Carbon Radioisotopes; L-Lactate Dehydrogenase; Malate Dehydrogenase; Mass Spectrometry; NAD; Oxidation-Reduction; Protein Binding; Tritium; Tryptophan | 1977 |
The contribution of tryptophan to the regulation of the NAD+ level in mouse liver.
Topics: Aging; Animals; Liver; Mice; NAD; Niacinamide; Nicotinic Acids; Organ Specificity; Tryptophan | 1975 |
Vitamin B6 nutritional status of pellagrins and their leucine tolerance.
Topics: Adult; Drug Tolerance; Humans; Leucine; Middle Aged; NAD; Nutritional Requirements; Pellagra; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1978 |
Mode of action of isoniazid on yeast.
Topics: Culture Media; Isoniazid; Lactobacillus; NAD; ortho-Aminobenzoates; Saccharomyces; Tryptophan | 1978 |
Lifetimes and NADH quenching of tryptophan fluorescence in pig heart lactate dehydrogenase.
Topics: Animals; Kinetics; L-Lactate Dehydrogenase; Myocardium; NAD; Oxidation-Reduction; Spectrometry, Fluorescence; Swine; Tryptophan | 1979 |
Lifetimes and NADH quenching of tryptophan fluorescence in pig heart cytoplasmic malate dehydrogenase.
Topics: Animals; Cytoplasm; Kinetics; Malate Dehydrogenase; Myocardium; NAD; Oxidation-Reduction; Protein Conformation; Swine; Tryptophan | 1979 |
The amino acid sequence of fragment A, an enzymically active fragment of diphtheria toxin. III. The chymotryptic peptides, the peptides derived by cleavage at tryptophan residues, and the complete sequence of the protein.
Topics: Adenosine Diphosphate Sugars; Amino Acid Sequence; Chymotrypsin; Diphtheria Toxin; NAD; Nucleotidyltransferases; Peptide Elongation Factors; Peptide Fragments; Ribose; Tryptophan | 1979 |
Nicotinamide adenine dinucleotide metabolism in Candida albicans.
Topics: Biological Transport; Candida albicans; Kinetics; NAD; Niacinamide; Nicotinic Acids; Tryptophan | 1979 |
The ultraviolet fluorescence spectra of DPN-linked isocitrate dehydrogenase from bovine heart.
Topics: Animals; Binding Sites; Cattle; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Myocardium; NAD; Oxidation-Reduction; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1975 |
Alteration of mice L-tryptophan metabolism by the organophosphorous acid triester diazinon.
Topics: Animals; Arylformamidase; Diazinon; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Models, Biological; NAD; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1992 |
Levels of reduced pyridine nucleotides and lens photodamage.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Lens, Crystalline; NAD; NADP; Oxidation-Reduction; Rabbits; Rana catesbeiana; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Tryptophan; Ultraviolet Rays; Xenopus | 1992 |
Specific binding of nucleotides and NAD+ to Clostridium difficile toxin A.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Bacterial Toxins; Binding Sites; Clostridioides difficile; Enterotoxins; Guanosine Triphosphate; Molecular Sequence Data; NAD; Nucleotides; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1992 |
Nucleotide exchange and cGMP phosphodiesterase activation by pertussis toxin inactivated transducin.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Animals; Catalysis; Cattle; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hydrolysis; Kinetics; NAD; Nucleotides; Pertussis Toxin; Rod Cell Outer Segment; Structure-Activity Relationship; Transducin; Tryptophan; Virulence Factors, Bordetella | 1991 |
Kynureninase and kynurenine 3-hydroxylase in mammalian tissues.
Topics: Animals; Eulipotyphla; Humans; Hydrolases; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mitochondria; Mixed Function Oxygenases; NAD; Organ Specificity; Rats; Rats, Inbred Strains; Species Specificity; Tryptophan; Tryptophan Oxygenase | 1991 |
Relationships between pteridine synthesis and tryptophan degradation.
Topics: Biopterins; Cells, Cultured; Enzyme Induction; Humans; Hydrolases; Interferon-gamma; Macrophages; NAD; Neopterin; Pteridines; Tryptophan; Tryptophan Oxygenase | 1991 |
Spectroscopic evidence for NADH-induced conformational changes in rabbit muscle aldolase.
Topics: Animals; Binding Sites; Energy Transfer; Fluorescence Polarization; Fructose-Bisphosphate Aldolase; Luminescent Measurements; Muscles; NAD; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Temperature; Tryptophan | 1991 |
Assessment of niacin status in humans.
Topics: Adult; Erythrocytes; Humans; Male; NAD; Niacin; Nutritional Status; Tryptophan | 1990 |
Fluorescence studies with malate dehydrogenase from Bradyrhizobium japonicum 3I1B-143 bacteroids: a two-tryptophan containing protein.
Topics: Kinetics; Lasers; Malate Dehydrogenase; NAD; Oxidation-Reduction; Protein Binding; Rhizobiaceae; Spectrometry, Fluorescence; Tryptophan | 1990 |
Tryptophan luminescence from liver alcohol dehydrogenase in its complexes with coenzyme. A comparative study of protein conformation in solution.
Topics: Alcohol Dehydrogenase; Amides; Animals; Chemical Phenomena; Chemistry; Coenzymes; Horses; Kinetics; Liver; Luminescent Measurements; Molecular Structure; NAD; Oxidation-Reduction; Protein Conformation; Pyrazoles; Solutions; Tryptophan | 1990 |
Room temperature phosphorescence of Trp-314 as a monitor of subunit communications in alcohol dehydrogenase from horse liver.
Topics: Alcohol Dehydrogenase; Amides; Animals; Coenzymes; Horses; Kinetics; Liver; Luminescent Measurements; Molecular Structure; NAD; Oxidation-Reduction; Protein Conformation; Temperature; Tryptophan | 1990 |
Critical time periods and the effect of tryptophan in malathion-induced developmental defects in Xenopus embryos.
Topics: Animals; Female; Malathion; Male; NAD; Teratogens; Time Factors; Tryptophan; Xenopus laevis | 1990 |
Mutation in the phosphoribosylpyrophosphate synthetase gene (prs) that results in simultaneous requirements for purine and pyrimidine nucleosides, nicotinamide nucleotide, histidine, and tryptophan in Escherichia coli.
Topics: Escherichia coli; Histidine; Mutation; NAD; Phosphoribosyl Pyrophosphate; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Purine Nucleosides; Purine-Nucleoside Phosphorylase; Pyrimidine Nucleosides; Ribose-Phosphate Pyrophosphokinase; Tryptophan; Uridine Phosphorylase | 1988 |
Tryptophan metabolism by the isolated rat liver cells--effects of leucine and its metabolites.
Topics: Acetoacetates; Animals; In Vitro Techniques; Keto Acids; Leucine; Liver; NAD; Pentosyltransferases; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1989 |
Effects of a dietary excess of leucine and of the addition of leucine and 2-oxo-isocaproate on the metabolism of tryptophan and niacin in isolated rat liver cells.
Topics: Animals; Caproates; In Vitro Techniques; Keto Acids; Kynurenine; Leucine; Liver; Male; NAD; Niacin; Niacinamide; Rats; Rats, Inbred Strains; Tryptophan; Xanthurenates | 1989 |
Biochemical markers for assessment of niacin status in young men: levels of erythrocyte niacin coenzymes and plasma tryptophan.
Topics: Adult; Biomarkers; Diet; Erythrocytes; Food, Fortified; Humans; Leucine; Male; NAD; NADP; Niacin; Nutritional Status; Tryptophan | 1989 |
Effects of dietary pyrazinamide, tryptophan, or nicotinic acid and gamma-ray irradiation on levels of NAD and NADP in various organs of mice.
Topics: Animals; Eating; Female; Gamma Rays; Mice; Mice, Inbred C3H; NAD; NADP; Niacin; Organ Specificity; Pyrazinamide; Thymus Gland; Tryptophan | 1989 |
Phosphorescence properties and protein structure surrounding tryptophan residues in yeast, pig, and rabbit glyceraldehyde-3-phosphate dehydrogenase.
Topics: Animals; Glyceraldehyde-3-Phosphate Dehydrogenases; In Vitro Techniques; Luminescent Measurements; Molecular Structure; Muscles; NAD; Protein Conformation; Rabbits; Saccharomyces cerevisiae; Spectrophotometry; Swine; Tryptophan | 1989 |
Influence of ethanol upon the introduction of tyrosine aminotransferase in liver, upon the NAD content in liver and brain, and upon the activity of glutamate oxalate aminotransferase and glutamate pyruvate aminotransferase in the serum of rats.
Topics: Adrenalectomy; Alanine Transaminase; Animals; Aspartate Aminotransferases; Brain Chemistry; Ethanol; Liver; Methionine; NAD; Niacinamide; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine Transaminase | 1985 |
Effect of dietary orotic acid on the levels of liver and blood NAD in rats.
Topics: Animals; Body Weight; Creatinine; Diet; DNA; Fats; Liver; Male; NAD; Niacin; Organ Size; Orotic Acid; Proteins; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Time Factors; Tryptophan | 1985 |
Utilization of tryptophan, nicotinamide and nicotinic acid as precursors for nicotinamide nucleotide synthesis in isolated rat liver cells.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Male; NAD; NADP; Niacin; Niacinamide; Rats; Rats, Inbred Strains; Tryptophan | 1988 |
Effects of diazinon on nucleotide and amino acid contents of chick embryos. Teratogenic considerations.
Topics: Abnormalities, Drug-Induced; Amino Acids; Animals; Chick Embryo; Diazinon; Insecticides; NAD; Niacinamide; Nucleotides; Tryptophan | 1985 |
Increased urinary excretion of tryptophan metabolites in rats exposed to nitrogen dioxide.
Topics: Animals; Body Weight; Kynurenic Acid; Liver; Male; NAD; NADP; Nitrogen Dioxide; Pyridoxal Phosphate; Rats; Rats, Inbred F344; Tryptophan; Xanthurenates | 1988 |
Fluorescence spectra of NADH/NAD, kynurenine, tryptophan, and tyrosine.
Topics: Kynurenine; NAD; Oxidation-Reduction; Oxidoreductases; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1988 |
Fluorescence lifetime and anisotropy studies with liver alcohol dehydrogenase and its complexes.
Topics: Acrylamide; Acrylamides; Alcohol Dehydrogenase; Animals; Fluorescence Polarization; Horses; Indoles; Kinetics; Liver; NAD; Protein Binding; Spectrometry, Fluorescence; Tryptophan | 1986 |
Interactions between apo-(D-beta-hydroxybutyrate dehydrogenase) and phospholipids studied by intrinsic and extrinsic fluorescence.
Topics: Apoenzymes; Apoproteins; Binding Sites; Diphenylhexatriene; Fluorescence Polarization; Hydroxybutyrate Dehydrogenase; NAD; Phospholipids; Protein Conformation; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tryptophan | 1986 |
Effect of leucine on intestinal absorption of tryptophan in rats.
Topics: Amino Acids, Essential; Animals; Caseins; Intestinal Absorption; Kinetics; Leucine; Liver; Male; NAD; Rats; Rats, Inbred Strains; Tryptophan | 1985 |
Spectrophotometric determination of some peptidases.
Topics: Amino Acid Oxidoreductases; Isoleucine; Leucine; Methionine; Methods; Microchemistry; NAD; Peptide Hydrolases; Peroxidases; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1970 |
Effects of tryptophan metabolites on enzymes of oxidative phosphorylation.
Topics: Acetoacetates; Adenine Nucleotides; Amino Acids; Animals; Antimycin A; Cyanides; Cytochromes; Depression, Chemical; Dicumarol; Hydroxybutyrates; In Vitro Techniques; Ketoglutaric Acids; Kynurenic Acid; Kynurenine; Liver; Manometry; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; NAD; Nitriles; ortho-Aminobenzoates; Oxidative Phosphorylation; Oxygen Consumption; Phenylbutyrates; Phenylhydrazines; Polarography; Rats; Rotenone; Spectrophotometry; Stimulation, Chemical; Temperature; Tryptophan; Uncoupling Agents; Xanthurenates | 1971 |
The effects of chronic phenobarbitone administration and subsequent withdrawal on the activity of rat liver tryptohan pyrrolase and their resemblance to those of ethanol.
Topics: Animals; Depression, Chemical; Ethanol; Humans; Hydrocortisone; Injections, Intraperitoneal; Kynurenine; Liver; NAD; NADP; Phenobarbital; Rats; Sodium Chloride; Sodium Salicylate; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Oxygenase | 1973 |
Effect of acetoacetate on liver and blood pyridine nucleotides in rats.
Topics: Acetoacetates; Administration, Oral; Animals; Deficiency Diseases; Depression, Chemical; Liver; Male; NAD; NADP; Nicotinic Acids; Rats; Tryptophan | 1973 |
The relation between urinary excretion of tryptophan and niacin metabolites and pyridine nucleotides in the liver in rats fed a tryptophan-deficient diet.
Topics: Adenine Nucleotides; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Deficiency Diseases; Female; Liver; NAD; NADP; Niacinamide; Nicotinic Acids; Nucleotides; Organ Size; Pyridones; Rats; Tryptophan | 1974 |
Enzymic demethylation of a carcinogenic tryptophan metabolite, 8-methoxykynurenic acid.
Topics: Animals; Carcinogens; Kidney; Kinetics; Kynurenic Acid; Liver; NAD; NADP; Organ Specificity; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Rats; Tryptophan | 1974 |
Effect of endotoxin on metabolic regulation in mice.
Topics: Animals; Carbon Radioisotopes; Cortisone; Cyproheptadine; Drug Antagonism; Endotoxins; Energy Metabolism; Enzyme Induction; Injections, Intraperitoneal; Injections, Intravenous; Kynurenine; Lethal Dose 50; Leucine; Liver; Mice; NAD; NADP; Orotic Acid; Protein Biosynthesis; RNA; Tryptophan; Tryptophan Oxygenase; Tyrosine Transaminase | 1973 |
Pyridine nucleotides in the thyroid gland. II. Effect of nicotinamide, nicotinic acid and L-tryptophan administration.
Topics: Animals; Kinetics; Male; NAD; NADP; Niacin; Niacinamide; Oxidation-Reduction; Rats; Thyroid Gland; Tryptophan | 1968 |
An assay procedure for nicotinamide-adenine dinucleotides in rat liver and other tissues.
Topics: Alcohol Oxidoreductases; Animals; Buffers; Chemistry Techniques, Analytical; Edetic Acid; Ethanol; Glucosephosphate Dehydrogenase; In Vitro Techniques; Indicators and Reagents; Liver; NAD; NADP; Niacinamide; Phenazines; Phenols; Phosphates; Rats; Spectrophotometry; Subcellular Fractions; Tryptophan | 1964 |
The involvement of a tryptophan residue of glutamate dehydrogenase in the binding of L-glutamate.
Topics: Chemical Phenomena; Chemistry; Glutamate Dehydrogenase; Glutamates; NAD; Spectrophotometry; Tryptophan | 1965 |
Nicotinic acid biosynthesis in prototrophs and tryptophan auxotrophs of Saccharomyces cerevisiae.
Topics: Amidohydrolases; Aspartic Acid; Glutamates; In Vitro Techniques; Molecular Biology; Mutation; NAD; Nicotinic Acids; Oxidoreductases; Pyridines; Saccharomyces; Tryptophan | 1966 |
Tryptophan as intermediate in dehydrogenase action. 3. Evidence for complete cycle of hydrogen transfer between substrate and tryptophanyl residues in rabbit muscle lactate dehydrogenase.
Topics: Animals; In Vitro Techniques; L-Lactate Dehydrogenase; Lactates; Muscles; NAD; Perchlorates; Rabbits; Tritium; Tryptophan; Urea | 1967 |
[On the question of indolyl-3-acetaldehyde-mutase in microorganisms].
Topics: Acetaldehyde; Alcohol Oxidoreductases; Ascomycota; Dialysis; Ethanol; Indoleacetic Acids; Indoles; Mitosporic Fungi; NAD; Oxidoreductases; Rhizobium; Spectrophotometry; Tryptophan | 1967 |
Enzymic formation of D-kynurenine from D-tryptophan.
Topics: Adenine Nucleotides; Animals; Hydrogen Peroxide; Ileum; In Vitro Techniques; Intestine, Small; Kynurenine; Methylene Blue; NAD; Nucleosides; Oxygen Consumption; Oxygenases; Rabbits; Tryptophan; Tryptophan Oxygenase | 1967 |
[The formation of nicotinamide-adenine-dinucleotide from tryptophan after whole-body irradiation].
Topics: Animals; Female; Liver; Mice; NAD; Radiation Effects; Tryptophan | 1967 |
Measurements of tryptophan pyrrolase in vivo: induction and feedback inhibition.
Topics: Adrenalectomy; Carbon Dioxide; Carbon Isotopes; Enzyme Induction; Feedback; Hypophysectomy; Liver; NAD; Niacinamide; Nicotinic Acids; Tryptophan; Tryptophan Oxygenase | 1967 |
Fluorescence of D-glyceraldehyde-3-phosphate dehydrogenase-substrate complexes.
Topics: Acetone; Animals; Binding Sites; Charcoal; Fluorescence; Glyceraldehyde; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerolphosphate Dehydrogenase; Glycerophosphates; Hydrogen-Ion Concentration; Iodoacetates; Methylation; Muscles; NAD; Phosphates; Protein Binding; Rabbits; Sulfhydryl Compounds; Tryptophan; Tyrosine; Yeasts | 1968 |
The pathway of biosynthesis of nicotinamide-adenine dinucleotide in rat mammary gland.
Topics: Animals; Female; Glucosyltransferases; Kinetics; Lactation; Mammary Glands, Animal; Models, Biological; NAD; Niacinamide; Nicotinic Acids; Nucleotides; Nucleotidyltransferases; Pregnancy; Rats; Tryptophan | 1968 |
The mechanism of end product inhibition of serine biosynthesis. 3. Physical and chemical properties of phosphoglycerate dehydrogenase.
Topics: Alcohol Oxidoreductases; Amino Acids; Benzoates; Binding Sites; Centrifugation, Zonal; Chemical Phenomena; Chemistry, Physical; Fluorescence; Glyceric Acids; Guanidines; Hydrogen-Ion Concentration; Mercury; Molecular Weight; NAD; Phosphates; Silver; Spectrum Analysis; Sulfhydryl Compounds; Tryptophan; Ultracentrifugation | 1968 |
The utilization of trytophan and its metabolites for pyridine nucleotide synthesis in tumors and host liver.
Topics: Adenine Nucleotides; Animals; Brain; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; In Vitro Techniques; Kidney; Liver; Lung; Mice; Muscles; NAD; Nucleotides; ortho-Aminobenzoates; Oxygen Consumption; Pyridines; Rats; Spleen; Tryptophan | 1968 |
The effect of glucagon and insulin on the prothrombin response to coumarin anticoagulants.
Topics: Acenocoumarol; Animals; Glucagon; Guinea Pigs; Insulin, Long-Acting; NAD; Prothrombin; Prothrombin Time; Tryptophan; Tyrosine | 1968 |
Studies on the biosynthesis of nicotinamide adenine dinucleotide (NAD) in mammals and its regulatory mechanism. I.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cats; Diabetes Mellitus, Experimental; Glutarates; Kidney; Liver; Liver Neoplasms; Mice; NAD; Rats; Tryptophan | 1967 |
The biosynthesis of NAD in the liver of irradiated mice.
Topics: Adrenalectomy; Animals; Carbon Isotopes; Chromatography; Hydrocortisone; Hydrolases; Liver; Mice; Mixed Function Oxygenases; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinic Acids; Nucleotides; Radiation Effects; Transaminases; Tryptophan; Tryptophan Oxygenase | 1968 |
The chemistry of flavines and flavorproteins. Photoreduction of flavines by amino acids.
Topics: Aldehydes; Benzene Derivatives; Carbon Dioxide; Dimethyl Sulfoxide; Edetic Acid; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Glycine; Kinetics; Light; NAD; Oxidation-Reduction; Phenylacetates; Potassium Iodide; Riboflavin; Serotonin; Temperature; Tryptophan; Urea | 1968 |
Feedback inhibition of glutamine synthetase of Neurospora crassa by nicotinamide-adenine dinucleotide.
Topics: Adenosine Triphosphate; Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Feedback; Glutamates; Glutamine; Guanine Nucleotides; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Ligases; NAD; Neurospora; ortho-Aminobenzoates; Phenylalanine; Quaternary Ammonium Compounds; Tryptophan; Tyrosine | 1968 |
Synthesis of indoleacetic acid from tryptophan via indolepyruvic acid in cell-free extracts of pea seedlings.
Topics: Aldehydes; Carbon Isotopes; Cell-Free System; Chromatography, Ion Exchange; Chromatography, Thin Layer; Indoleacetic Acids; Indoles; Ketoglutaric Acids; NAD; Plants; Pyridoxal Phosphate; Pyruvates; Thiamine Pyrophosphate; Tryptophan | 1968 |
The role of lysyl residues in the structure and reactivity of cytochrome B5 reductase.
Topics: Acetates; Amides; Anhydrides; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Cytochromes; Drug Stability; Electron Transport; Fluorescence; Kinetics; Liver; Lysine; Microsomes; NAD; Nitrobenzenes; Oxidoreductases; Protein Denaturation; Spectrophotometry; Succinates; Sulfonic Acids; Tryptophan | 1968 |
Studies on the biosynthesis of NAD by a direct method of tracing metabolism in vivo.
Topics: Animals; Carbon Isotopes; Liver; Mice; NAD; Niacinamide; Nicotinic Acids; Pyridines; Tryptophan | 1967 |
Enzymatic conversion of phenylpyruvate to phenylacetate.
Topics: Acetates; Alcaligenes; Aldehydes; Carboxy-Lyases; Chromatography, Gas; Chromatography, Gel; Enzyme Induction; Hydrogen-Ion Concentration; Infrared Rays; Kinetics; Magnesium; Methods; NAD; Oxidoreductases; Oxygen Consumption; Phenylhydrazines; Pyruvates; Spectrum Analysis; Thiamine; Thiamine Pyrophosphate; Tryptophan; Xylenes | 1968 |
Studies on the biosynthesis of nicotinamide adenine dinucleotide (NAD) in mammals and its regulatory mechanism. II.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Chromatography; Chromatography, Paper; Digestive System; Liver; Mice; NAD; Niacinamide; Nicotinic Acids; Pyridines; Radiometry; Tryptophan | 1967 |
Studies on oxidative phosphorylation. XVII. Physical and chemical properties of factor B.
Topics: Adenosine Triphosphate; Amides; Amino Acids; Centrifugation, Density Gradient; Coloring Agents; Cystine; Electrophoresis, Disc; Iodine; Mitochondria; NAD; Nucleotides; Oxidative Phosphorylation; Proteins; Spectrum Analysis; Sulfhydryl Compounds; Sulfonic Acids; Sulfur; Tryptophan; Ultracentrifugation; Ultraviolet Rays | 1969 |
The biosynthesis and degradation of nicotinamide-adenine dinucleotide during cick embryonic development.
Topics: Aging; Animals; Carbon Isotopes; Chick Embryo; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinic Acids; Phosphoric Monoester Hydrolases; Tryptophan | 1969 |
Separation and characterization of HeLa alkaline pyrophosphatase isoenzymes.
Topics: Adenine Nucleotides; Alkaline Phosphatase; Binding Sites; Centrifugation, Density Gradient; Chromatography, Gel; Cysteine; Cytosine Nucleotides; Dialysis; Electrophoresis; Electrophoresis, Disc; Guanine Nucleotides; HeLa Cells; Hydrogen-Ion Concentration; Isoenzymes; Magnesium; Molecular Weight; NAD; Nucleotides; Phenylalanine; Pyrophosphatases; Stereoisomerism; Tryptophan; Uracil Nucleotides | 1969 |
Phosphorescence and energy transfer in enzymes.
Topics: Alcohol Oxidoreductases; Amylases; Animals; Aspergillus; Bacillus subtilis; Carboxypeptidases; Cattle; Chymotrypsin; Cold Temperature; Energy Transfer; Enzymes; Luminescent Measurements; Methods; Muramidase; NAD; Pancreas; Papain; Pepsin A; Ribonucleases; Saccharomyces; Spectrum Analysis; Tryptophan; Tyrosine | 1969 |
Tryptophan and nitrogen metabolism and pregnancy of the rat as affected by dietary supplementations with leucine and with amino acid mixtures.
Topics: Amino Acids; Animals; Deficiency Diseases; Diet; Dietary Proteins; Feces; Female; Fetal Death; Fetus; Isoleucine; Kidney; Leucine; Liver; Male; Maternal-Fetal Exchange; NAD; Niacinamide; Nicotinic Acids; Nitrogen; Pregnancy; Pregnancy, Animal; Rats; Tryptophan; Valine | 1970 |
Effect of hormones on the biosynthesis of nicotinic acid from tryptophan in man.
Topics: Carboxy-Lyases; Chlorotrianisene; Chromatography, Ion Exchange; Diethylstilbestrol; Humans; Hydrocortisone; Male; NAD; Niacinamide; Nicotinic Acids; Picolinic Acids; Progestins; Prostatic Neoplasms; Pyridones; Tryptophan | 1970 |
Regulation of enzymes involved in the conversion of tryptophan to nicotinamide adenine dinucleotide in a colorless strain of Xanthomonas pruni.
Topics: Amidohydrolases; Enzyme Induction; Hydrolases; Kynurenine; Mutation; NAD; ortho-Aminobenzoates; Oxygenases; Tryptophan; Tryptophan Oxygenase; Xanthomonas | 1970 |
Characterization of a fluorescent complex between auramine O and horse liver alcohol dehydrogenase.
Topics: Alcohol Oxidoreductases; Aniline Compounds; Animals; Binding Sites; Chemical Phenomena; Chemistry; Dialysis; Energy Transfer; Fluorescent Dyes; Fluorometry; Horses; Kinetics; Liver; NAD; Protein Binding; Pyrazoles; Spectrophotometry; Tryptophan | 1970 |
Spectrophotometric studies of binary and ternary complexes of octopine dehydrogenase.
Topics: Amino Acids; Animals; Arginine; Binding Sites; Chemical Phenomena; Chemistry; Methods; Molecular Weight; Mollusca; Muscles; NAD; Oxidoreductases; Spectrophotometry; Tryptophan; Ultraviolet Rays | 1970 |
Evidence for a linear correlation between the level of dietary tryptophan and hepatic NAD concentration and for a systematic variation in tissue NAD concentration in the mouse and the rat.
Topics: Adrenal Glands; Adrenalectomy; Animals; Circadian Rhythm; Diet; Liver; Male; Mice; Myocardium; NAD; Rats; Spleen; Tryptophan; Tryptophan Oxygenase | 1970 |
Tryptophan fluorescence quenching in horse liver alcohol dehydrogenase.
Topics: Alcohol Oxidoreductases; Animals; Binding Sites; Chemical Phenomena; Chemistry; Fluorescence; Horses; Liver; NAD; Tryptophan | 1970 |
A study of tryptophan tritiation in supernatant malate dehydrogenase from pig heart.
Topics: Animals; Chemical Precipitation; Chromatography, Paper; Dialysis; Malate Dehydrogenase; Malates; Myocardium; NAD; Peptides; Perchlorates; Swine; Tritium; Tryptophan | 1970 |
NAD biosynthesis in polymorphonuclear leucocytes of guinea pigs. Comparative studies on different NAD precursors in intact cells.
Topics: Animals; Carbon Isotopes; Cell-Free System; Guinea Pigs; Leukocytes; NAD; Niacinamide; Nicotinic Acids; Nucleotides; Pyridines; Tryptophan | 1970 |
The enzymology of prephenate dehydrogenase in Bacillus subtilis.
Topics: Bacillus subtilis; Chemical Phenomena; Chemistry; Cyclohexanes; Enzyme Repression; Fluorometry; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mutation; NAD; Oxidoreductases; Phenylalanine; Phenylpyruvic Acids; Protein Binding; Pyruvates; Stereoisomerism; Tryptophan; Tyrosine | 1970 |
Phosphorescence studies of environmental heterogeneity for tryptophyl residues in proteins.
Topics: Alcohol Oxidoreductases; Animals; Chemical Phenomena; Chemistry; Energy Transfer; Fluorescence; Horses; Liver; Luminescent Measurements; Models, Chemical; NAD; Papain; Spectrum Analysis; Trypsin; Tryptophan; Yeasts | 1970 |
Glyceraldehyde phosphate dehydrogenase of Escherichia coli. Structural and catalytic properties.
Topics: Acetylesterase; Adenine Nucleotides; Amino Acids; Animals; Arginine; Benzoates; Charcoal; Crystallization; Cysteine; Escherichia coli; Formates; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanidines; Hydrogen-Ion Concentration; Iodoacetates; Lysine; Mercaptoethanol; Molecular Weight; Muscles; NAD; Oxidation-Reduction; Peptides; Protein Denaturation; Rabbits; Spectrophotometry; Sulfhydryl Compounds; Sulfides; Trypsin; Tryptophan; Ultracentrifugation; Ultraviolet Rays | 1971 |
Hormonal alteration of efficiency of conversion of tryptophan to urinary metabolites of niacin in man.
Topics: Chlorotrianisene; Contraceptives, Oral; Depression, Chemical; Diethylstilbestrol; Humans; Hydrocortisone; Male; NAD; Niacinamide; Nicotinic Acids; Norethynodrel; Prostatic Diseases; Pyridones; Stimulation, Chemical; Tryptophan | 1971 |
[Study by fluorescence of the binding of TNS with horse liver alcohol dehydrogenase (HLADH)].
Topics: Alcohol Oxidoreductases; Animals; Binding Sites; Chemical Phenomena; Chemistry; Energy Transfer; Ethanol; Fluorescence; Horses; Liver; NAD; Naphthalenes; Pyrazoles; Spectrum Analysis; Tryptophan | 1971 |
Nicotinamide adenine dinucleotide in developing chick embryo.
Topics: Aging; Alcohol Oxidoreductases; Animals; Chick Embryo; Egg White; Egg Yolk; Female; Hydrogen-Ion Concentration; Liver; NAD; Niacinamide; Nicotinic Acids; Ovalbumin; Pyridines; Tryptophan | 1971 |
Studies on the hydrogen-transfer reactions catalyzed by pyridine nucleotide linked dehydrogenases.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen; L-Lactate Dehydrogenase; Muscles; NAD; Nephropidae; Tritium; Tryptophan | 1971 |
Fluorescence changes associated with denaturation of alcohol dehydrogenase.
Topics: Alcohol Oxidoreductases; Aniline Compounds; Animals; Chemical Phenomena; Chemistry; Fluorescence; Fluorescent Dyes; Fluorometry; Horses; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; Naphthalenes; Osmolar Concentration; Protein Denaturation; Pyrazoles; Sodium Chloride; Spectrophotometry; Sulfonic Acids; Toluene; Tryptophan; Ultraviolet Rays | 1971 |
Studies on tryptophan metabolism in male subjects treated with hydrocortisone.
Topics: Chromatography, Ion Exchange; Humans; Hydrocortisone; Kynurenic Acid; Kynurenine; Male; NAD; Pyridoxine; Statistics as Topic; Tryptophan | 1971 |
Evidence for distinct kynureninase and hydroxykynureninase activities in Neurospora crassa.
Topics: Cell-Free System; Chromatography, DEAE-Cellulose; Culture Media; Enzyme Induction; Fluorometry; Hydrolases; Kynurenine; Magnesium Sulfate; Models, Chemical; NAD; Neurospora; ortho-Aminobenzoates; Pyridoxal Phosphate; Tryptophan | 1971 |
Role of zinc in horse liver alcohol dehydrogenase. Coenzyme and substrate binding.
Topics: Acetates; Adenine Nucleotides; Alcohol Oxidoreductases; Alcohols; Amides; Animals; Apoproteins; Binding Sites; Ethanol; Horses; Kinetics; Liver; Macromolecular Substances; Mathematics; NAD; Nitro Compounds; Nucleoside Diphosphate Sugars; Protein Binding; Ribose; Spectrometry, Fluorescence; Tryptophan; Zinc | 1972 |
Multiple forms of drosophila alcohol dehydrogenase. IV. Protein fluorescence studies.
Topics: Alcohol Oxidoreductases; Animals; Drosophila melanogaster; Electrophoresis; Kinetics; NAD; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1972 |
Tryptic conversion of cytochrome b 5 reductase to an active derivative containing two peptide chains.
Topics: Amino Acids; Binding Sites; Catalysis; Chromatography, Gel; Chromatography, Ion Exchange; Cytochromes; Electrophoresis, Disc; Flavin-Adenine Dinucleotide; Flavoproteins; Molecular Weight; NAD; Oxidoreductases; Peptides; Protein Binding; Protein Conformation; Protein Denaturation; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectrophotometry; Sulfhydryl Compounds; Trypsin; Tryptophan; Ultracentrifugation | 1972 |
Kinetics and mechanism of the isoalloxazine (flavine) dehydrogenation of dimethyl dihydrophthalates.
Topics: Aniline Compounds; Chemical Phenomena; Chemistry; Diazomethane; Esters; Flavins; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Methanol; Models, Chemical; NAD; Nitro Compounds; Nitrobenzenes; Oxidation-Reduction; Phthalic Acids; Polarography; Spectrometry, Fluorescence; Tryptophan | 1972 |
Spectroscopic properties of N-bromosuccinimide-modified horse heart cytochrome c + .
Topics: Amino Acid Sequence; Amino Acids; Animals; Chemical Phenomena; Chemistry; Cytochrome c Group; Electron Transport; Horses; Hydrogen-Ion Concentration; Iron; Methionine; Myocardium; NAD; Oxidation-Reduction; Oxidoreductases; Phenols; Pyrrolidinones; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Succinate Dehydrogenase; Succinimides; Tryptophan | 1972 |
Abnormal tryptophan metabolism in patients with scurvy-type skin.
Topics: Acetates; Adult; Aminohippuric Acids; Black or African American; Black People; Ethnicity; Glucuronates; Hemosiderosis; Humans; Indoles; Kynurenic Acid; Kynurenine; Male; NAD; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Scurvy; South Africa; Sulfuric Acids; Tryptophan; Xanthurenates | 1973 |
Metabolism of pyridine nucleotides and its relation to DNA synthesis in regenerating mouse liver.
Topics: Adenine Nucleotides; Animals; DNA; Female; Hepatectomy; Hydrolases; Kynurenine; Liver; Liver Regeneration; Mice; Mice, Inbred Strains; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotidyltransferases; ortho-Aminobenzoates; Pentosyltransferases; Transaminases; Tryptophan | 1972 |
Reciprocal induction and repression of serine dehydratase and phosphoglycerate dehydrogenase by proteins and dietary-essential amino acids in rat liver.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Caseins; Dietary Proteins; Egg Proteins; Enzyme Induction; Enzyme Repression; Glutens; Glyceric Acids; L-Serine Dehydratase; Liver; Male; Methionine; Models, Biological; NAD; Organophosphorus Compounds; Protein Biosynthesis; Rats; Serine; Threonine; Tryptophan; Valine | 1973 |
Pyridine nucleotide biosynthesis in Claviceps.
Topics: Ascomycota; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Culture Media; Hydrolysis; NAD; Niacinamide; Nicotinic Acids; Nucleotides; Pyridines; Solvents; Time Factors; Tryptophan | 1973 |
Conformational studies on lipoamide dehydrogenase from pig heart. 2. Spectroscopic studies on the apoenzyme and the monomeric and dimeric forms.
Topics: Animals; Apoproteins; Circular Dichroism; Dihydrolipoamide Dehydrogenase; Dioxins; Energy Transfer; Flavin-Adenine Dinucleotide; Hot Temperature; Macromolecular Substances; Myocardium; NAD; Optical Rotatory Dispersion; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry; Swine; Tryptophan | 1973 |
Interaction of chloride ion with horse liver alcohol dehydrogenase-reduced nicotinamide adenine dinucleotide complexes.
Topics: Alcohol Oxidoreductases; Animals; Binding Sites; Chemical Phenomena; Chemistry; Horses; Liver; NAD; Optical Rotatory Dispersion; Oxidation-Reduction; Protein Binding; Protein Conformation; Sodium Chloride; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan | 1973 |
[Significance of nicotinic acid amide for the biosynthesis of NAD in the isolated perfused rat liver].
Topics: Animals; In Vitro Techniques; Liver; NAD; Niacinamide; Nicotinic Acids; Perfusion; Rats; Tryptophan | 1972 |
The mechanism of inhibition of rat liver tryptophan pyrrolase activity by 4-hydroxypyrazolo(3,4-d)pyrimidine (Allopurinol).
Topics: Allopurinol; Alloxan; Animals; Ascorbic Acid; Cyclic AMP; Ethanol; Heme; Hydrocortisone; Hypoxanthines; Injections, Intraperitoneal; Liver; Male; NAD; Rats; Tryptophan; Tryptophan Oxygenase; Xanthine Oxidase; Xanthines | 1973 |
Fluorescence properties of octopine dehydrogenase.
Topics: Amino Acids, Dicarboxylic; Arginine; Chemical Phenomena; Chemistry; Guanidines; Hydrogen-Ion Concentration; Ligands; NAD; Osmolar Concentration; Oxidoreductases; Protein Binding; Spectrometry, Fluorescence; Temperature; Tryptophan | 1973 |
Effect of alcohol on albumin synthesis by the isolated perfused rat liver.
Topics: Albumins; Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Carbonates; Ethanol; In Vitro Techniques; Kinetics; Liver; Male; Methylene Blue; NAD; Oxidation-Reduction; Perfusion; Rats; Sodium; Tryptophan; Urea | 1973 |
Functional groups in the activity and regulation of Escherichia coli citrate synthase.
Topics: Amino Acids; Benzoates; Benzyl Compounds; Binding Sites; Citrate (si)-Synthase; Cysteine; Densitometry; Disulfides; Escherichia coli; Esters; Formates; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Ketoglutaric Acids; Kinetics; Methylene Blue; Molecular Weight; NAD; Nitro Compounds; Nitrobenzenes; Oxidation-Reduction; Oxo-Acid-Lyases; Phenols; Photochemistry; Rose Bengal; Tryptophan | 1973 |
Crystal structure of 1-(2-indol-3-ylethyl)-3-carbamidopyridinium chloride, an intramolecular model of the nicotinamide adenine dinucleotide--tryptophan charge-transfer complex.
Topics: Electron Transport; Molecular Conformation; NAD; Pyridinium Compounds; Tryptophan | 1974 |
The mechanism of end product inhibition of serine biosynthesis. IV. Subunit structure of phosphoglycerate dehydrogenase and steady state kinetic studies of phosphoglycerate oxidation.
Topics: Alcohol Oxidoreductases; Alkylation; Amino Acids; Binding Sites; Carbon Radioisotopes; Crystallization; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Glyceric Acids; Kinetics; Macromolecular Substances; NAD; Organophosphorus Compounds; Oxidation-Reduction; Peptide Fragments; Pyridines; Serine; Spectrometry, Fluorescence; Temperature; Trypsin; Tryptophan | 1974 |
Studies of glutamate dehydrogenase: chemical modification and quantitative determination of tryptophan residues.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Amino Acids; Animals; Benzyl Compounds; Binding Sites; Cattle; Chromatography, Gel; Chymotrypsin; Circular Dichroism; Dansyl Compounds; Glutamate Dehydrogenase; Guanine Nucleotides; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; Oxidation-Reduction; Peptide Fragments; Phenols; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Tryptophan; Ultracentrifugation | 1974 |
Molecular orbital study on the interaction between coenzymes and enzymes; NAD+ or NADH and dehydrogenases.
Topics: Apoproteins; Chemical Phenomena; Chemistry, Physical; Glyceraldehyde-3-Phosphate Dehydrogenases; Indoles; Magnetic Resonance Spectroscopy; Models, Chemical; NAD; Oxidoreductases; Spectrophotometry, Atomic; Sulfhydryl Compounds; Tryptophan | 1974 |
[Proceedings: NAD biosynthesis from tryptophan in mouse liver].
Topics: Animals; DNA; Hydrolases; Kynurenine; Liver; Liver Regeneration; Mice; NAD; Niacinamide; Nicotinic Acids; Thymidine; Tryptophan | 1972 |
Inhibition of liver phenylalanine and tryptophan hydroxylating enzyme systems in vitro and in vivo.
Topics: Aminopterin; Animals; Brain Chemistry; Coumarins; Enzyme Induction; Enzymes; Flavonoids; In Vitro Techniques; Liver; Liver Extracts; Methyldopa; Mice; Mixed Function Oxygenases; NAD; NADP; Phenylacetates; Phenylalanine; Rats; Serotonin; Tryptophan | 1966 |
Feedback control of rat liver tryptophan pyrrolase. I. End product inhibition of trytophan pyrrolase activity.
Topics: Animals; Buffers; Chromatography; Electrophoresis; Enzymes; Hot Temperature; Kinetics; Liver; Molecular Weight; NAD; NADP; Niacinamide; Nicotinic Acids; Nucleotides; Oxidoreductases; Rats; Tryptophan; Ultracentrifugation | 1967 |
Indolelactate dehydrogenase from Clostridium sporogenes.
Topics: Clostridium; Indoles; Kinetics; L-Lactate Dehydrogenase; NAD; NADP; Tryptophan | 1968 |
Regulation of NAD biosynthesis via the pyridine nucleotide cycle.
Topics: Adenosine Triphosphate; Animals; Bacillus; Carbon Isotopes; Escherichia coli; Hypophysectomy; In Vitro Techniques; Liver; NAD; NADP; Niacinamide; Nicotinic Acids; Nucleotides; Pyridines; Pyrophosphatases; Rats; Transferases; Tryptophan; Tryptophan Oxygenase | 1968 |
Prevention and remission by adrenocortical steriods of nicotinamide deficiency disease. II. A study of the mechanism.
Topics: Adrenal Cortex Hormones; Animals; Corticosterone; Deficiency Diseases; NAD; NADP; Niacinamide; Nucleotides; Pyridines; Rats; Tryptophan | 1968 |
Effect in man of the addition of tryptophan oniacin to the diet on the excretion of their metabolites.
Topics: Creatinine; Diet; Female; Humans; Kynurenic Acid; NAD; NADP; Niacinamide; Nicotinic Acids; Nitrogen; Pyridones; Tryptophan; Urea; Xanthurenates | 1969 |
Effects of amino acid derivatives and drugs on the metabolism of tryptophan.
Topics: Adrenal Glands; Adrenalectomy; Animals; Brain; Carbon Dioxide; Carbon Isotopes; Chromatography, Paper; Deficiency Diseases; Depression, Chemical; Hydrocortisone; Hydroxyindoleacetic Acid; Liver; Metabolism; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; NAD; NADP; Oxidation-Reduction; Protein Biosynthesis; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase; Yohimbine | 1971 |
Tryptophan availability as a control of hepatic pyridine nucleotide concentration in mice.
Topics: Adrenalectomy; Allopurinol; Animals; Depression, Chemical; Hydrocortisone; Kinetics; Liver; Male; Mice; NAD; NADP; Stimulation, Chemical; Tryptophan; Tryptophan Oxygenase | 1971 |
[Tryptophan metabolism of streptomycetes. 3. Tryptophan degradation in cell free extracts of Streptomyces cremeus].
Topics: Ammonium Sulfate; Coenzymes; Enzyme Induction; Methylene Blue; NAD; NADP; ortho-Aminobenzoates; Streptomyces; Toluidines; Tryptophan | 1971 |
[Hydroxylation of phenylalanine by Hydrogenomonas eutropha H 16].
Topics: Cell-Free System; Chromatography, Gel; Enzyme Induction; Mixed Function Oxygenases; NAD; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pseudomonas; Tryptophan; Tyrosine | 1972 |
Regulation of pyridine nucleotide levels and ratios in Neurospora crassa.
Topics: Culture Media; Genetics, Microbial; Glucosephosphate Dehydrogenase; Kynurenine; Mixed Function Oxygenases; Mutation; NAD; NADP; Neurospora; Neurospora crassa; Nicotinic Acids; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Tryptophan | 1972 |
Influence of azacytidine on the induction of tyrosine aminotransferase and the NAD metabolism in rat liver.
Topics: Adrenalectomy; Animals; Azacitidine; Cell Nucleus; Enzyme Induction; Hydrocortisone; Liver; NAD; Rats; Tryptophan; Tyrosine Transaminase | 1984 |
Effects of excess leucine on growth and tryptophan and niacin metabolism in rats.
Topics: Animals; Body Weight; Diet; Erythrocytes; Female; Hydroxyindoleacetic Acid; Isoleucine; Leucine; NAD; NADP; Nicotinic Acids; Organ Size; Pellagra; Quinolinic Acids; Rats; Time Factors; Tryptophan; Valine; Vitamin B 6 Deficiency | 1980 |
Do organophosphate insecticides inhibit the conversion of tryptophan to NAD+ in ovo?
Topics: Abnormalities, Drug-Induced; Animals; Arylformamidase; Chick Embryo; Diazinon; Female; Insecticides; Morphogenesis; NAD; Ovum; Tryptophan | 1982 |
The differences in growth and activity of the tryptophan-NAD pathway between Wistar and Sprague Dawley strains of rats fed on tryptophan-limited diet.
Topics: Animals; Carboxy-Lyases; Growth; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; NAD; Niacin; Niacinamide; Nicotinic Acids; Quinolinic Acids; Rats; Rats, Inbred Strains; Species Specificity; Tryptophan; Tryptophan Oxygenase | 1982 |
Probable mechanisms of regulation of the utilization of dietary tryptophan, nicotinamide and nicotinic acid as precursors of nicotinamide nucleotides in the rat.
Topics: Animals; Diet; Liver; Male; NAD; Niacin; Niacinamide; Nicotinamidase; Nicotinic Acids; Pentosyltransferases; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1982 |
Effect of L-leucine-supplemented diet on the nicotinamide adenine dinucleotide content of rat liver.
Topics: Animals; Diet; Dose-Response Relationship, Drug; Intestinal Absorption; Leucine; Liver; Male; NAD; Niacinamide; Nicotinic Acids; Pentosyltransferases; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase | 1982 |
Effect of L-tryptophan and L-leucine on biosynthesis of niacin-related compounds in Saccharomyces carlsbergensis.
Topics: Culture Media; Leucine; NAD; NADP; Niacin; Niacinamide; Nicotinamidase; Pentosyltransferases; Saccharomyces; Tryptophan | 1982 |
Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra.
Topics: Animals; Castration; Estrone; Female; Liver; NAD; NADP; Niacinamide; Pellagra; Rats; Rats, Inbred Strains; Tryptophan | 1984 |
Influence of N-methylformamide on the development, the NAD synthesis, and the activity of the ADPR transferase of rat embryos.
Topics: Animals; Embryo, Mammalian; Female; Fetal Growth Retardation; Fetal Resorption; Formamides; Maternal-Fetal Exchange; Methionine; NAD; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Pregnancy; Rats; Rats, Inbred Strains; Tryptophan | 1983 |
Influence of D-galactosamine upon the NAD-metabolism in rat liver.
Topics: Adrenalectomy; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Liver; Methionine; NAD; Niacinamide; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains; Tryptophan | 1983 |
Luminescence studies on the conformational behavior of horse-liver alcohol dehydrogenase.
Topics: Adenosine; Adenosine Diphosphate; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Energy Transfer; Ethanol; Horses; Liver; Luminescent Measurements; Mathematics; NAD; Protein Conformation; Tryptophan | 1984 |
Comparative phosphorescence and optically detected magnetic resonance studies of pig and yeast glyceraldehyde-3-phosphate dehydrogenase.
Topics: Animals; Glyceraldehyde-3-Phosphate Dehydrogenases; Luminescent Measurements; Muscles; NAD; Rabbits; Saccharomyces cerevisiae; Spectrophotometry; Swine; Tryptophan | 1984 |
Effect of tryptophan and/or casein supplementation on NAD levels in livers of the rats fed on niacin- and protein-free diet.
Topics: Animals; Caseins; Diet; Liver; Male; NAD; Niacin; Protein Deficiency; Rats; Rats, Inbred Strains; Tryptophan | 1984 |
The effect of pyrazines on the metabolism of tryptophan and nicotinamide adenine dinucleotide in the rat. Evidence of the formation of a potent inhibitor of aminocarboxy-muconate-semialdehyde decarboxylase from pyrazinamide.
Topics: Animals; Carboxy-Lyases; Kidney; Liver; Male; NAD; Nicotinic Acids; Poly(ADP-ribose) Polymerases; Pyrazinamide; Pyrazines; Rats; Rats, Inbred Strains; Tryptophan | 1981 |
The radiation inactivation of glutamate dehydrogenase.
Topics: Binding Sites; Cysteine; Electrons; Enzyme Activation; Free Radicals; Gamma Rays; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; NAD; Pulse Radiolysis; Tryptophan; Tyrosine | 1983 |
In vivo conversion of tryptophan to nicotinic acid in rats studied by simultaneous incorporation of [3H]-tryptophan and [14C]-nicotinic acid into liver NAD and NADP.
Topics: Animals; Dietary Proteins; Liver; NAD; NADP; Niacin; Rats; Rats, Inbred Strains; Tryptophan; Weaning | 1983 |
Effect of leucine and alpha-ketoisocaproic acid on NAD biosynthesis from tryptophan or nicotinic acid in the isolated rat liver cells.
Topics: Animals; In Vitro Techniques; Keto Acids; Ketone Bodies; Leucine; Liver; NAD; Nicotinic Acids; Palmitic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1983 |
Kynurenine hydroxylase mutants of the nematode Caenorhabditis elegans.
Topics: Animals; Caenorhabditis; Chromosome Mapping; Genetic Complementation Test; Kynurenine 3-Monooxygenase; Mixed Function Oxygenases; Mutation; NAD; NADP; Tryptophan | 1980 |
Time-resolved fluorescence of the two tryptophans in horse liver alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Horses; Kinetics; Liver; Mathematics; NAD; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1981 |
Fluorescence quenching of liver alcohol dehydrogenase by acrylamide.
Topics: Acrylamides; Alcohol Oxidoreductases; Fluorescence; Liver; NAD; Protein Binding; Spectrometry, Fluorescence; Trifluoroethanol; Tryptophan | 1982 |
Effects of niacin deficiency on pyridine nucleotide levels and enzyme activities in various organs of young growing quail.
Topics: Animals; Body Weight; Coturnix; Dose-Response Relationship, Drug; Liver; Muscles; NAD; NADP; Niacin; Nicotinic Acids; Quail; Tryptophan | 1982 |
Increased in growth rate and activity of the tryptophan-NAD pathway caused by di-n-butylphthalate in rats fed on a tryptophan-limited diet.
Topics: Animals; Body Weight; Dibutyl Phthalate; Diet; Male; NAD; Phthalic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1982 |
Inhibition of rat brain tryptophan metabolism by ethanol withdrawal and possible involvement of the enhanced liver tryptophan pyrrolase activity.
Topics: Animals; Behavior, Animal; Brain; Corticosterone; Ethanol; Humans; Liver; Male; NAD; Rats; Serotonin; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase | 1980 |
Metabolic control for maintaining NAD in rats fed on tryptophan-limiting amino acid diets.
Topics: Amino Acids; Animals; Body Weight; Diet; Kidney; Liver; Male; NAD; Rats; Tryptophan | 1980 |
Possible involvement of the enhanced tryptophan pyrrolase activity in the corticosterone- and starvation-induced increases in concentrations of nicotinamide-adenine dinucleotides (phosphates) in rat liver.
Topics: Allopurinol; Animals; Corticosterone; Dactinomycin; Glucose; Liver; Male; NAD; NADP; Propranolol; Rats; Starvation; Stimulation, Chemical; Tryptophan; Tryptophan Oxygenase | 1981 |
Effect of natural oestrogens on tryptophan metabolism: evidence for interference of oestrogens with kynureninase.
Topics: Aged; Estradiol; Estriol; Estrogens; Female; Humans; Hydrolases; Kynurenine; Menopause; Middle Aged; NAD; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan | 1980 |
The kynurenine load test, an adjunct to the tryptophan load test.
Topics: 3-Hydroxyanthranilic Acid; Aged; Female; Humans; Kynurenine; Menopause; Middle Aged; NAD; Pyridoxine; Tryptophan | 1980 |
Dietary tryptophan level and the enzymes of tryptophan NAD pathway.
Topics: Animals; Carboxy-Lyases; Diet; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kidney; Liver; Male; NAD; Nicotinic Acids; Pentosyltransferases; Rats; Tryptophan; Tryptophan Oxygenase | 1980 |
Strain differences in the development of acute tolerance to ethanol.
Topics: Animals; Body Temperature; Diet; Drug Tolerance; Ethanol; Liver; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; NAD; Species Specificity; Tryptophan | 1980 |
Identification of Glu173 as the critical amino acid residue for the ADP-ribosyltransferase activity of Clostridium botulinum C3 exoenzyme.
Topics: 3T3 Cells; ADP Ribose Transferases; Animals; Base Sequence; Binding Sites; Botulinum Toxins; Glutamic Acid; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship; Tryptophan | 1995 |
Two tryptophans at the active site of UDP-glucose 4-epimerase from Kluyveromyces fragilis.
Topics: Binding Sites; Bromosuccinimide; Energy Transfer; Kinetics; Kluyveromyces; NAD; Spectrometry, Fluorescence; Tryptophan; UDPglucose 4-Epimerase | 1995 |
A method for increasing the concentration of a specific internal metabolite in steady-state systems.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Anthranilate Synthase; Chorismate Mutase; Diffusion; Feedback; Kinetics; Models, Biological; NAD; Protein Biosynthesis; Saccharomyces cerevisiae; Transaminases; Tryptophan; Tryptophan Synthase | 1994 |
Active-site mutations of diphtheria toxin. Tryptophan 50 is a major determinant of NAD affinity.
Topics: Binding Sites; Diphtheria Toxin; Kinetics; Mutagenesis, Site-Directed; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases; Spectrometry, Fluorescence; Tryptophan | 1994 |
Dietary niacin deficiency lowers tissue poly(ADP-ribose) and NAD+ concentrations in Fischer-344 rats.
Topics: Animals; Eating; Kidney; Liver; Lung; Male; Myocardium; NAD; Niacin; Pellagra; Poly Adenosine Diphosphate Ribose; Rats; Rats, Inbred F344; Tryptophan; Vitamin B Deficiency | 1994 |
Quantitative efficacy of niacin sources for chicks: nicotinic acid, nicotinamide, NAD and tryptophan.
Topics: Analysis of Variance; Animal Feed; Animals; Biological Assay; Chickens; Dose-Response Relationship, Drug; Eating; Liver; Male; Muscles; NAD; NADP; Niacin; Niacinamide; Regression Analysis; Tryptophan; Weight Gain | 1993 |
Poly(ADP-ribose) polymerase activity and DNA strand breaks are affected in tissues of niacin-deficient rats.
Topics: Animals; Body Weight; DNA Damage; Eating; Liver; Lung; Lymphocytes; Male; Muscles; NAD; Niacin; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Spleen; Tryptophan; Vitamin B Deficiency; Weight Gain | 1993 |
Ligand-dependent changes in intrinsic fluorescence of S-adenosylhomocysteine hydrolase: implications for the mechanism of inhibitor-induced inhibition.
Topics: Adenosylhomocysteinase; Animals; Binding Sites; Computer Simulation; Energy Transfer; Fluorescence; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Ligands; Liver; Models, Molecular; NAD; Protein Structure, Tertiary; Rats; Spectrometry, Fluorescence; Tryptophan | 1993 |
A study of colchicine tubulin complex by donor quenching of fluorescence energy transfer.
Topics: Acrylamide; Acrylamides; Alcohol Dehydrogenase; Animals; Colchicine; Dimethyl Sulfoxide; Energy Transfer; Horses; Liver; NAD; Spectrometry, Fluorescence; Tryptophan; Tubulin | 1993 |
Structure of D-glyceraldehyde-3-phosphate dehydrogenase from Palinurus versicolor carrying the fluorescent NAD derivatives at 2.7 A resolution.
Topics: Animals; Binding Sites; Crystallization; Energy Transfer; Fluorescence; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen Bonding; Molecular Structure; NAD; Nephropidae; Tryptophan; Ultraviolet Rays; X-Ray Diffraction | 1993 |
The effect of niacin deficiency on diethylnitrosamine-induced hepatic poly(ADP-ribose) levels and altered hepatic foci in the Fischer-344 rat.
Topics: Animals; Diethylnitrosamine; Glutathione Transferase; Liver; Male; NAD; Niacin; Poly Adenosine Diphosphate Ribose; Rats; Rats, Inbred F344; Tryptophan | 1995 |
Interaction of nucleotides with the NAD(H)-binding domain of the proton-translocating transhydrogenase of Rhodospirillum rubrum.
Topics: Biological Transport; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; NAD; NADP Transhydrogenases; Oxidation-Reduction; Rhodospirillum rubrum; Spectrometry, Fluorescence; Tryptophan | 1996 |
Mutation of Tyr235 in the NAD(H)-binding subunit of the proton-translocating nicotinamide nucleotide transhydrogenase of Rhodospirillum rubrum affects the conformational dynamics of a mobile loop and lowers the catalytic activity of the enzyme.
Topics: Asparagine; Binding Sites; Biological Transport; Catalysis; Magnetic Resonance Spectroscopy; NAD; NADP Transhydrogenases; Phenylalanine; Protein Conformation; Rhodospirillum rubrum; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan; Tyrosine | 1996 |
NAD+ biosynthesis and metabolic fluxes of tryptophan in hepatocytes isolated from rats fed a clofibrate-containing diet.
Topics: Animals; Cells, Cultured; Clofibrate; Diet; Liver; Male; NAD; Niacin; Pentosyltransferases; Rats; Rats, Sprague-Dawley; Tryptophan | 1996 |
Effects of NAD+ binding on the luminescence of tryptophans 84 and 310 of glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Fluorescence; Geobacillus stearothermophilus; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; Luminescent Measurements; Mutagenesis, Site-Directed; Mutation; NAD; Protein Conformation; Tryptophan | 1996 |
Investigation into the catalytic role for the tryptophan residues within domain III of Pseudomonas aeruginosa exotoxin A.
Topics: ADP Ribose Transferases; Bacterial Toxins; Binding Sites; Bromosuccinimide; Catalysis; Crystallography, X-Ray; Exotoxins; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; NAD; NAD+ Nucleosidase; Oxidation-Reduction; Phenylalanine; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan; Virulence Factors | 1996 |
Increased conversion ratio of tryptophan to niacin by the administration of clofibrate, a hypolipidemic drug, to rats.
Topics: Animals; Clofibrate; Hypolipidemic Agents; Liver; Male; NAD; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Weaning; Weight Gain | 1996 |
Photoaffinity labelling of human poly(ADP-ribose) polymerase catalytic domain.
Topics: Affinity Labels; Amino Acid Sequence; Azides; Binding Sites; DNA Mutational Analysis; Humans; Light; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Fragments; Photochemistry; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Sequence Analysis; Tryptophan | 1997 |
Molecular mechanism of regulation of the pyruvate dehydrogenase complex from E. coli.
Topics: Coenzymes; Diethyl Pyrocarbonate; Enzyme Activation; Escherichia coli; Kinetics; NAD; Protein Binding; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Spectrometry, Fluorescence; Thiamine Pyrophosphate; Tryptophan | 1997 |
LDH-C4-substrate binary complexes studied by intrinsic fluorescence method.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Isoenzymes; L-Lactate Dehydrogenase; Mice; NAD; Spectrometry, Fluorescence; Tryptophan | 1997 |
NAD+ biosynthesis from tryptophan in the presence of nicotinic acid or vice versa by rat hepatocytes--effect of clofibrate-feeding.
Topics: Animals; Biological Transport; Clofibrate; Glutarates; Hydrolases; Liver; Male; Microbodies; NAD; Niacin; Rats; Rats, Sprague-Dawley; Tryptophan | 1998 |
Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes.
Topics: Alanine; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Binding Sites; Coenzymes; Crystallography, X-Ray; Horses; Ligands; Liver; Models, Molecular; NAD; Niacinamide; Phenylalanine; Structure-Activity Relationship; Substrate Specificity; Tryptophan; Valine | 1998 |
Differential effects of kynurenine and tryptophan treatment on quinolinate immunoreactivity in rat lymphoid and non-lymphoid organs.
Topics: Animals; Immunohistochemistry; Injections, Intraperitoneal; Kynurenine; Lymphoid Tissue; Male; NAD; Organ Specificity; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Tryptophan | 1998 |
Resonant energy transfer from proteins to pyridine nucleotides in mitochondria.
Topics: Animals; Energy Transfer; In Vitro Techniques; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Proteins; Rats; Spectrometry, Fluorescence; Tryptophan | 1998 |
Role of ground and excited singlet state oxygen in the red light-induced stimulation of Escherichia coli cell growth.
Topics: Azides; Deuterium Oxide; Escherichia coli; Histidine; Lasers; Light; NAD; NADH Dehydrogenase; Oxygen; Photobiology; Singlet Oxygen; Time Factors; Tryptophan; Water | 1999 |
A fluorescence investigation of the active site of Pseudomonas aeruginosa exotoxin A.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Bacterial Toxins; Binding Sites; Circular Dichroism; Exotoxins; Fluorescence Polarization; Kinetics; Molecular Sequence Data; Mutation; NAD; NAD+ Nucleosidase; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Recombinant Proteins; Tryptophan; Virulence Factors | 1999 |
The arginine 276 anchor for NADP(H) dictates fluorescence kinetic transients in 3 alpha-hydroxysteroid dehydrogenase, a representative aldo-keto reductase.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Arginine; Binding Sites; Kinetics; Liver; Methionine; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Rats; Recombinant Proteins; Spectrometry, Fluorescence; Static Electricity; Time Factors; Tryptophan | 1999 |
Peroxisome-proliferator regulates key enzymes of the tryptophan-NAD+ pathway.
Topics: Animals; Biomarkers; Body Weight; Cells, Cultured; Eating; Hypertrophy; Liver; Male; NAD; Peroxisome Proliferators; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Tryptophan | 1999 |
Hypoxanthine-guanine phosphoribosyltransferase deficiency and erythrocyte synthesis of pyridine coenzymes.
Topics: Adolescent; Adult; Amide Synthases; Child; Child, Preschool; Erythrocytes; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Infant; Kinetics; Lesch-Nyhan Syndrome; Male; Middle Aged; NAD; Nicotinic Acids; Pentosyltransferases; Purine Nucleotides; Purines; Pyridines; Pyrimidine Nucleotides; Tryptophan | 1999 |
Evidence for the stabilization of NADPH relative to NADP(+) on the dIII components of proton-translocating transhydrogenases from Homo sapiens and from Rhodospirillum rubrum by measurement of tryptophan fluorescence.
Topics: Animals; Binding Sites; Fluorescence; Hominidae; Humans; Kinetics; NAD; NADP; NADP Transhydrogenases; Oxidation-Reduction; Rhodospirillum rubrum; Tryptophan | 1999 |
Evidence for increased de novo synthesis of NAD in immune-activated RAW264.7 macrophages: a self-protective mechanism?
Topics: Animals; Benzamides; Cell Line; Dexamethasone; Enzyme Inhibitors; Interferon-gamma; Macrophage Activation; Macrophages; Mice; NAD; NG-Nitroarginine Methyl Ester; Niacinamide; Nitric Oxide Synthase; Poly(ADP-ribose) Polymerase Inhibitors; Quinolinic Acid; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase | 1999 |
Niacin as a potential AIDS preventive factor.
Topics: Acquired Immunodeficiency Syndrome; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Humans; Membrane Glycoproteins; NAD; NAD+ Nucleosidase; Niacin; Pellagra; Tryptophan | 1999 |
Drug selectivity is determined by coupling across the NAD+ site of IMP dehydrogenase.
Topics: Adenosine Diphosphate; Animals; Cricetinae; Cricetulus; Drug Resistance; Drug Synergism; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Mutagenesis, Site-Directed; Mycophenolic Acid; NAD; Ribavirin; Spectrometry, Fluorescence; Tritrichomonas foetus; Tryptophan | 2000 |
Effects of peroxisome-proliferators on the TRP-NAD pathway.
Topics: Animals; Carboxy-Lyases; Cells, Cultured; Clofibrate; Female; Liver; Male; NAD; NADP; Niacin; Oxidation-Reduction; Pentosyltransferases; Peroxisome Proliferators; Peroxisomes; Phenothiazines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan | 1999 |
Specific enzymatic chlorination of tryptophan and tryptophan derivatives.
Topics: Halogens; NAD; Oxidation-Reduction; Oxidoreductases; Peroxidases; Substrate Specificity; Tryptophan | 1999 |
Deoxyhypusine synthase generates and uses bound NADH in a transient hydride transfer mechanism.
Topics: Hydrogen; NAD; Oxidoreductases Acting on CH-NH Group Donors; Spectrometry, Fluorescence; Tryptophan | 2000 |
Stopped-flow reaction kinetics of recombinant components of proton-translocating transhydrogenase with physiological nucleotides.
Topics: Dose-Response Relationship, Drug; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; NAD; NADP Transhydrogenases; Nucleotides; Oxidation-Reduction; Protons; Recombinant Proteins; Spectrometry, Fluorescence; Temperature; Tryptophan | 2000 |
IDO induction in IFN-gamma activated astroglia: a role in improving cell viability during oxidative stress.
Topics: Astrocytes; Astrocytoma; Benzamides; Cell Survival; Enzyme Induction; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; NAD; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured | 2000 |
Tryptophan metabolism through the kynurenine pathway in rat brain and liver slices.
Topics: Aerobiosis; Animals; Brain; In Vitro Techniques; Kynurenine; Liver; Male; NAD; Organ Specificity; Oxygen; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Tryptophan | 2000 |
Functional interactions in cytochrome P450BM3. Evidence that NADP(H) binding controls redox potentials of the flavin cofactors.
Topics: Animals; Bacterial Proteins; Binding, Competitive; Cytochrome P-450 Enzyme System; Electron Transport; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Flavoproteins; Mixed Function Oxygenases; Mutagenesis, Site-Directed; NAD; NADP; NADP Transhydrogenases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Phosphorus Radioisotopes; Protein Binding; Protein Structure, Tertiary; Protons; Rats; Spectrometry, Fluorescence; Tryptophan | 2000 |
Diphtheria toxin NAD affinity and ADP ribosyltransferase activity are reduced at tryptophan 153 substitutions for alanine or phenylalanine.
Topics: Adenosine Diphosphate Ribose; Alanine; Amino Acid Substitution; Diphtheria Toxin; Mutagenesis, Site-Directed; NAD; Peptide Fragments; Phenylalanine; Poly(ADP-ribose) Polymerases; Temperature; Tryptophan | 2000 |
Trp-676 facilitates nicotinamide coenzyme exchange in the reductive half-reaction of human cytochrome P450 reductase: properties of the soluble W676H and W676A mutant reductases.
Topics: Alanine; Binding Sites; Catalysis; Cytochrome c Group; Enzyme Activation; Flavin-Adenine Dinucleotide; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Structure, Tertiary; Recombinant Proteins; Solubility; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 2000 |
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.
Topics: Animals; Antitubercular Agents; Diet; Eating; Liver; Male; NAD; NADP; Niacin; Pyrazinamide; Quinolinic Acid; Rats; Rats, Wistar; Serotonin; Tryptophan; Weight Gain | 2001 |
Elevation of blood NAD level after moderate exercise in young women and mice.
Topics: Adult; Animals; Exercise; Female; Humans; Male; Mice; Mice, Inbred ICR; NAD; NADP; Physical Exertion; Tryptophan | 2001 |
Protein-protein interaction using tryptophan analogues: novel spectroscopic probes for toxin-elongation factor-2 interactions.
Topics: ADP Ribose Transferases; Bacterial Toxins; Cloning, Molecular; Escherichia coli; Exotoxins; Kinetics; NAD; Peptide Elongation Factor 2; Promoter Regions, Genetic; Proteins; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Recombinant Proteins; Spectrophotometry; Tryptophan; Virulence Factors | 2001 |
[Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats].
Topics: Animals; Kidney; Liver; Male; Mushroom Poisoning; NAD; Niacin; Rats; Rats, Wistar; Tryptophan | 2001 |
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats.
Topics: 3-Hydroxyanthranilic Acid; Adenine; Animals; Kidney; Kynurenic Acid; Liver; Male; NAD; Niacin; Quinolinic Acid; Rats; Rats, Wistar; Renal Insufficiency; Tryptophan; Xanthurenates | 2001 |
Abundant type 10 17 beta-hydroxysteroid dehydrogenase in the hippocampus of mouse Alzheimer's disease model.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxyacyl CoA Dehydrogenases; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Base Sequence; Binding Sites; Cloning, Molecular; Disease Models, Animal; DNA, Complementary; Hippocampus; Humans; Mice; Mice, Transgenic; Mitochondria; Molecular Sequence Data; NAD; Presynaptic Terminals; Protein Isoforms; Protein Structure, Tertiary; Signal Transduction; Steroids; Tryptophan | 2002 |
Elucidation of the toxic mechanism of the plasticizers, phthalic acid esters, putative endocrine disrupters: effects of dietary di(2-ethylhexyl)phthalate on the metabolism of tryptophan to niacin in rats.
Topics: Administration, Oral; Animals; Body Weight; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Energy Intake; Liver; NAD; NADP; Niacin; Organ Size; Rats; Tryptophan | 2002 |
Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae.
Topics: Aerobiosis; Anaerobiosis; Gene Deletion; Genes, Fungal; Hydrolases; NAD; Niacin; Pentosyltransferases; Saccharomyces cerevisiae; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type III; Symporters; Tryptophan | 2002 |
Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.
Topics: Animals; Diet; Fats; Fatty Liver; Feeding Behavior; Liver; Male; NAD; NADP; Niacin; Organ Size; Orotic Acid; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Vitamin B Deficiency; Weight Gain | 2002 |
Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity.
Topics: Animals; Antitubercular Agents; Carboxy-Lyases; Diet; Eating; Injections, Intraperitoneal; Kidney; Kynurenic Acid; Liver; Male; NAD; Niacin; Pyrazinamide; Rats; Rats, Wistar; Tryptophan; Weight Gain; Xanthurenates | 2002 |
Kynurenines and the respiratory parameters on rat heart mitochondria.
Topics: 3-Hydroxyanthranilic Acid; Animals; Free Radical Scavengers; In Vitro Techniques; Kinetics; Kynurenine; Male; Mitochondria, Heart; Mitochondrial Proteins; NAD; ortho-Aminobenzoates; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Succinates; Tryptophan | 2003 |
Tryptophan availability selectively limits NO-synthase induction in macrophages.
Topics: Animals; Arginine; Cell Line; Enzyme Induction; Interferon-gamma; Kynurenine; Macrophages; Mice; NAD; Nitric Oxide; Nitric Oxide Synthase; Tryptophan; Tryptophan Oxygenase; Tumor Necrosis Factor-alpha | 2003 |
Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor.
Topics: Alcohol Oxidoreductases; Animals; Binding Sites; Cell Differentiation; Crystallography, X-Ray; DNA-Binding Proteins; Fluorescence Resonance Energy Transfer; Humans; Kinetics; Models, Chemical; Models, Molecular; NAD; Oxidation-Reduction; Phosphoproteins; Plasmids; Protein Binding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Transcription, Genetic; Tryptophan; X-Ray Diffraction | 2003 |
Inhibition of indoleamine 2,3-dioxygenase activity in IFN-gamma stimulated astroglioma cells decreases intracellular NAD levels.
Topics: Astrocytes; Astrocytoma; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; NAD; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured | 2003 |
Tryptophan phosphorescence spectroscopy reveals that a domain in the NAD(H)-binding component (dI) of transhydrogenase from Rhodospirillum rubrum has an extremely rigid and conformationally homogeneous protein core.
Topics: Acrylamide; Dimerization; Escherichia coli; Glycerol; Kinetics; Luminescent Measurements; Models, Molecular; NAD; NADP; NADP Transhydrogenases; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protons; Rhodospirillum rubrum; Spectrometry, Fluorescence; Spectrophotometry; Temperature; Time Factors; Tryptophan | 2003 |
Diphosphopyridine nucleotide-tryptophan interactions.
Topics: Coenzymes; NAD; Tryptophan | 1961 |
Spectrophotometric studies of diphosphopyridine nucleotide tryptophan interaction.
Topics: Coenzymes; NAD; Spectrophotometry; Tryptophan | 1960 |
EFFECTS OF BACTERIAL ENDOTOXINS ON METABOLISM. VI. THE ROLE OF TRYPTOPHAN PYRROLASE IN RESPONSE OF MICE TO ENDOTOXIN.
Topics: Adrenalectomy; Animals; Cortisone; Endotoxins; Liver; Mice; NAD; Niacin; Niacinamide; Nicotinic Acids; Nucleotides; Peroxidases; Polysaccharides; Polysaccharides, Bacterial; Proteins; Research; Salmonella typhimurium; Serratia marcescens; Tryptophan; Tryptophan Oxygenase | 1963 |
THE CONVERSION OF SHIKIMIC ACID INTO CERTAIN AROMATIC COMPOUNDS BY CELL-FREE EXTRACTS OF AEROBACTER AEROGENES AND ESCHERICHIA COLI.
Topics: Adenosine Triphosphate; Chromatography; Enterobacter aerogenes; Escherichia coli; Metabolism; NAD; ortho-Aminobenzoates; Phenylpyruvic Acids; Pyruvates; Research; Shikimic Acid; Spectrophotometry; Tryptophan | 1963 |
[TRIALS OF A NEW ANTIHYPERTENSIVE, ALPHA-METHYL-DOPA (ALDOMET) WITH SPECIAL REFERENCE TO CHANGES IN RETINAL BLOOD FLOW].
Topics: Angiotensins; Antihypertensive Agents; Blood Circulation; Blood Pressure; Blood Pressure Determination; Dopamine; Epinephrine; Hemodynamics; Methyldopa; NAD; Norepinephrine; Phenylalanine; Renin; Retinal Vessels; Serotonin; Tryptophan; Tyrosine | 1963 |
STUDIES ON MORPHINE. IV. EFFECTS OF SOME METABOLITES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
Topics: Alanine; Cyanides; Fluoroacetates; Glutamine; Iodoacetates; Mice; Morphine; NAD; Nalorphine; Niacin; Niacinamide; Pharmacology; Pyridines; Pyridoxine; Research; Serine; Toxicology; Tryptophan | 1963 |
HARTNUP DISEASE IN TWO SIBLINGS. CLINICAL OBSERVATIONS AND BIOCHEMICAL STUDIES.
Topics: Adolescent; Ataxia; Child; Eczema; Genetics, Medical; Hartnup Disease; Humans; NAD; NADP; Niacin; Nicotinic Acids; Pellagra; Protein Deficiency; Renal Aminoacidurias; Siblings; Tryptophan | 1964 |
A COMPARATIVE STUDY OF THE REGULATION OF PYRIDINE NUCLEOTIDE FORMATION.
Topics: Bacillus subtilis; Carbon Isotopes; Cryptococcus; Culture Media; Escherichia coli; Genetics; Liver; Metabolism; NAD; Niacin; Nicotinic Acids; Phosphotransferases; Rats; Research; Salmonella typhimurium; Serratia marcescens; Tetrahymena; Transferases; Tryptophan; Vitamin B Deficiency; Yeasts | 1964 |
STUDIES OF PROTEIN AND BOUND COENZYME FLUORESCENCE OF LACTATE DEHYDROGENASES.
Topics: Animals; Cattle; Coenzymes; Fluorescence; Fluorometry; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Muscles; Myocardium; NAD; Poultry; Research; Spectrophotometry; Tryptophan; Tyrosine | 1964 |
NICOTINAMIDE ADENINE DINUCLEOTIDE LEVELS IN RAT BRAIN.
Topics: Brain; Dietary Fats; Metabolism; NAD; NADP; Niacin; Niacinamide; Nicotinic Acids; Pharmacology; Protein Deficiency; Rats; Research; Reserpine; Tryptophan | 1964 |
INFLUENCE OF GELATIN ON GROWTH AND LIVER PYRIDINE NUCLEOTIDE CONCENTRATION OF THE RAT.
Topics: Amino Acids; Caseins; Diet; Gelatin; Glycine; Growth; Liver; NAD; NADP; Niacin; Nicotinic Acids; Nucleotides; Rats; Research; Tryptophan | 1964 |
FETAL DEATH FROM NICOTINAMIDE-DEFICIENT DIET AND ITS PREVENTION BY CHLORPROMAZINE AND IMIPRAMINE.
Topics: Animals; Avitaminosis; Chlorpromazine; Diet; Female; Fetal Death; Fetus; Imipramine; Liver; NAD; Niacin; Niacinamide; Nicotinic Acids; Pharmacology; Pregnancy; Pregnancy, Animal; Rats; Research; Tryptophan | 1964 |
DIVERGENT RESPONSE TO INHIBITION BY PHENYLALANINE AND TRYPTOPHAN HYDROXYLATING SYSTEMS IN VITRO.
Topics: Amino Acids; Ascorbic Acid; Benzoates; Borates; Dimercaprol; Enzyme Inhibitors; Hydroxylation; In Vitro Techniques; Liver; Mixed Function Oxygenases; NAD; Pharmacology; Phenylalanine; Pterins; Rats; Research; Thioctic Acid; Tryptophan | 1964 |
ENZYMATIC FORMATION OF CATECHOL FROM ANTHRANILIC ACID.
Topics: Benzene; Benzoates; Carbon Isotopes; Catechols; Glycols; Kynurenic Acid; Levulinic Acids; Metabolism; Mixed Function Oxygenases; NAD; NADP; ortho-Aminobenzoates; Oxidoreductases; Pseudomonas; Research; Salicylic Acid; Tryptophan | 1964 |
PITUITARY INFLUENCE OF PYRIDINE NUCLEOTIDE METABOLISM OF RAT LIVER.
Topics: Adrenal Glands; Brain Chemistry; Fluorometry; Hypophysectomy; Intestines; Kidney; Liver; Lung; Metabolism; Muscles; Myocardium; NAD; NADP; Niacin; Niacinamide; Pharmacology; Pituitary Gland; Rats; Research; Spectrophotometry; Spleen; Tryptophan | 1964 |
REGULATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE BIOSYNTHESIS BY ADENOSINE TRIPHOSPHATE.
Topics: Adenosine Triphosphate; Carbon Isotopes; Chromatography; Glucosyltransferases; Liver Extracts; Metabolism; NAD; Niacin; Nicotinic Acids; Phosphates; Phosphoric Monoester Hydrolases; Rats; Tryptophan; Ultracentrifugation | 1964 |
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. I. ENZYMIC FORMATION OF GLUTARIC ACID FROM 3-HYDROXYANTHRANILIC ACID.
Topics: 3-Hydroxyanthranilic Acid; Amino Acids; Animals; Benzene; Carbon Dioxide; Carbon Isotopes; Cats; Chromatography; Coenzyme A; Electrophoresis; Glutarates; Keto Acids; Kynurenine; Liver; Metabolism; NAD; ortho-Aminobenzoates; Pseudomonas; Pyridines; Research; Tryptophan | 1965 |
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. II. ENZYMIC FORMATION OF ALPHA-AMINOMUCONIC ACID FROM 3-HYDROXYANTHRANILIC ACID.
Topics: 3-Hydroxyanthranilic Acid; Acids; Aldehydes; Animals; Benzene; Carboxy-Lyases; Cats; Chromatography; Dicarboxylic Acids; Edetic Acid; Electrophoresis; Hydrogen-Ion Concentration; Liver; Metabolism; NAD; ortho-Aminobenzoates; Oxidoreductases; Pyridines; Research; Tryptophan | 1965 |
EVIDENCE FOR THE PARTICIPATION OF TRYPTOPHAN AS INTERMEDIATE IN TRANSFER OF HYDROGEN BETWEEN DIPHOSPHOPYRIDINE NUCLEOTIDE AND SUBSTRATE IN YEAST ALCOHOL DEHYDROGENASE.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Coenzymes; Hydrogen; NAD; Oxidation-Reduction; Radiometry; Research; Tritium; Tryptophan | 1965 |
STUDIES ON THE BIOSYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE. II. A ROLE OF PICOLINIC CARBOXYLASE IN THE BIOSYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE FROM TRYPTOPHAN IN MAMMALS.
Topics: Animals; Carbon Isotopes; Cats; Diabetes Mellitus, Experimental; Glutarates; Kidney; Kynurenine; Ligases; Liver; Mammals; Metabolism; NAD; Nucleotides; Phosphotransferases; Radiometry; Rats; Research; Transferases; Tryptophan | 1965 |
Fluorometric studies of ligand-induced conformational changes of CD38.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Binding Sites; Humans; Hydrolysis; Kinetics; Ligands; Membrane Glycoproteins; Mice; Models, Molecular; NAD; Niacinamide; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Temperature; Tryptophan | 2003 |
NAD biosynthesis: identification of the tryptophan to quinolinate pathway in bacteria.
Topics: Arylformamidase; Bacteria; Chromosomes, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Complementation Test; Hydrolases; Kinetics; Molecular Sequence Data; NAD; Oxidoreductases; Quinolinic Acid; Tryptophan | 2003 |
Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats.
Topics: Animals; Dose-Response Relationship, Drug; Eating; Liver; Male; NAD; NADP; Niacinamide; Nicotinic Acids; Predictive Value of Tests; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Weaning; Weight Gain | 2004 |
NAD levels in the rat primary cultured hepatocytes affected by peroxisome-proliferators.
Topics: Animals; Cells, Cultured; Clofibrate; Hepatocytes; NAD; Peroxisome Proliferators; Rats; Tryptophan | 2003 |
The effects of phthalate esters on the tryptophan-niacin metabolism.
Topics: 3-Hydroxyanthranilic Acid; Animals; Dibutyl Phthalate; Diethylhexyl Phthalate; Kynurenic Acid; Liver; Male; NAD; Niacin; ortho-Aminobenzoates; Phthalic Acids; Plasticizers; Rats; Rats, Wistar; Tryptophan; Xanthurenates | 2003 |
Global position and recruitment of HATs and HDACs in the yeast genome.
Topics: Acetyltransferases; Cell Cycle; DNA-Binding Proteins; Genome; Histone Acetyltransferases; Histone Deacetylases; NAD; Protein Kinases; Ribosomal Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirtuin 2; Sirtuins; Spores, Fungal; Transcription Factors; Tryptophan | 2004 |
Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation.
Topics: Animals; Biomarkers; Carboxy-Lyases; Chromatography, High Pressure Liquid; Gene Expression; Hepatocytes; Hypolipidemic Agents; Immunohistochemistry; Lipids; Lipoproteins; Liver Function Tests; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microscopy, Electron, Transmission; Models, Statistical; NAD; Organ Size; Pentosyltransferases; Peroxisome Proliferators; Peroxisomes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tryptophan | 2005 |
Conversion ratio of tryptophan to niacin in Japanese women fed a purified diet conforming to the Japanese Dietary Reference Intakes.
Topics: Adult; Diet; Female; Humans; Japan; Male; NAD; NADP; Niacin; Niacinamide; Nutrition Policy; Sex Characteristics; Tryptophan | 2004 |
Mechanistic investigation of a highly active phosphite dehydrogenase mutant and its application for NADPH regeneration.
Topics: Deuterium; Escherichia coli Proteins; Kinetics; Mutation; NAD; NADH, NADPH Oxidoreductases; NADP; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structural Homology, Protein; Time Factors; Tryptophan; Xylitol | 2005 |
Study on the influence of potassium iodate on the metabolism of Escherichia coli by intrinsic fluorescence.
Topics: Escherichia coli; Fluorescence; Iodates; NAD; Potassium Compounds; Tryptophan | 2006 |
Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis.
Topics: Animals; Carboxy-Lyases; Kidney; Liver; Male; NAD; Nephrosis; Niacin; Niacinamide; Puromycin Aminonucleoside; Rats; Rats, Wistar; Serum Albumin; Tryptophan; Weight Gain | 2006 |
Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor a
Topics: Animals; Base Sequence; Binding Sites; Carboxy-Lyases; Chlorocebus aethiops; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 4; Humans; Liver; Mice; Mice, Transgenic; Molecular Sequence Data; NAD; Peroxisome Proliferators; PPAR alpha; Promoter Regions, Genetic; Pyrimidines; Signal Transduction; Transcription Initiation Site; Transfection; Tryptophan | 2006 |
Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.
Topics: Analysis of Variance; Animals; Antitubercular Agents; Carboxy-Lyases; Clofibrate; Diet, Fat-Restricted; Diet, Protein-Restricted; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hypolipidemic Agents; Kidney; Liver; Male; Models, Animal; NAD; Peroxisome Proliferators; Pyrazinamide; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Tryptophan; Weight Gain | 2006 |
The guinea-pig is a poor animal model for studies of niacin deficiency and presents challenges in any study using purified diets.
Topics: Animals; Bone Marrow; Caseins; Dietary Supplements; Disease Models, Animal; Gelatin; Guinea Pigs; Humans; Male; NAD; Niacin; Survival Analysis; Tryptophan; Weight Gain | 2007 |
The role of tryptophan metabolism in iNOS transcription and nitric oxide production by chicken macrophage cells upon treatment with interferon gamma.
Topics: Animals; Cell Line, Tumor; Chickens; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Macrophages; NAD; Nitric Oxide; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Transcription, Genetic; Tryptophan | 2008 |
Homotropic allosteric control in clostridial glutamate dehydrogenase: different mechanisms for glutamate and NAD+?
Topics: Allosteric Regulation; Bacterial Proteins; Clostridium symbiosum; Glutamate Dehydrogenase; Glutamates; Mutation; NAD; Phenylalanine; Tryptophan | 2008 |
Fluorescence spectroscopy as a promising tool for a polyphasic approach to pseudomonad taxonomy.
Topics: Amino Acids, Aromatic; Bacterial Typing Techniques; DNA, Bacterial; Genotype; NAD; Pseudomonas; Sensitivity and Specificity; Spectrometry, Fluorescence; Tryptophan | 2009 |
Two-photon autofluorescence microscopy of multicolor excitation.
Topics: Animals; Cell Line; Humans; Microscopy, Fluorescence, Multiphoton; NAD; Tryptophan | 2009 |
Comparison of the nicotinamide catabolism among rat strains.
Topics: Animals; Body Weight; Eating; Male; NAD; NADP; Niacinamide; Rats; Rats, Inbred Strains; Solubility; Species Specificity; Tryptophan; Vitamins; Water | 2009 |
Redox-linked conformational dynamics in apoptosis-inducing factor.
Topics: Amino Acid Sequence; Animals; Apoptosis; Apoptosis Inducing Factor; Catalytic Domain; Crystallography, X-Ray; Eukaryotic Cells; Mice; Models, Molecular; Molecular Sequence Data; NAD; Oxidation-Reduction; Peptides; Protein Binding; Protein Folding; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Alignment; Stereoisomerism; Surface Properties; Tryptophan | 2009 |
Role of tryptophan 95 in substrate specificity and structural stability of Sulfolobus solfataricus alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Amino Acid Substitution; Archaeal Proteins; Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Genes, Archaeal; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; NAD; Protein Conformation; Protein Denaturation; Recombinant Proteins; Spectrometry, Fluorescence; Substrate Specificity; Sulfolobus solfataricus; Temperature; Tryptophan | 2009 |
Imaging of epithelial tissue in vivo based on excitation of multiple endogenous nonlinear optical signals.
Topics: Animals; Cricetinae; Epithelium; Fluorescence; Humans; Hydrogen-Ion Concentration; Image Enhancement; Microscopy, Fluorescence, Multiphoton; NAD; Optics and Photonics; Photons; Tryptophan | 2009 |
An analytical method for the measurement of acid metabolites of tryptophan-NAD pathway and related acids in urine.
Topics: Acids; Chromatography, High Pressure Liquid; NAD; Spectrometry, Mass, Electrospray Ionization; Tryptophan | 2010 |
Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients.
Topics: Adult; Critical Illness; Female; Humans; Kynurenine; Male; Middle Aged; NAD; Renal Insufficiency; Sepsis; Tryptophan | 2010 |
Characterizing the origin of autofluorescence in human esophageal epithelium under ultraviolet excitation.
Topics: Barrett Esophagus; Biopsy; Collagen; Epithelium; Esophagus; Fluorescence; Humans; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Mucous Membrane; NAD; Optics and Photonics; Tryptophan; Ultraviolet Rays | 2010 |
Native fluorescence spectroscopic evaluation of chemotherapeutic effects on malignant cells using nonnegative matrix factorization analysis.
Topics: Algorithms; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Female; Flavins; Humans; NAD; Reference Standards; Sensitivity and Specificity; Spectrometry, Fluorescence; Tretinoin; Tryptophan | 2011 |
Tryptophan 697 modulates hydride and interflavin electron transfer in human methionine synthase reductase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Biocatalysis; Electron Transport; Ferredoxin-NADP Reductase; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Flavoproteins; Humans; Hydrogen; Kinetics; Mutant Proteins; NAD; NADP; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Sequence Alignment; Tryptophan | 2011 |
Synthesis of silica particles and their application as supports for alcohol dehydrogenases and cofactor immobilizations: conformational changes that lead to switch in enzyme stereoselectivity.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Circular Dichroism; Coenzymes; Enzymes, Immobilized; Horses; Kinetics; Liver; NAD; Nanoparticles; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Unfolding; Silicon Dioxide; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Substrate Specificity; Tryptophan | 2012 |
Stokes shift spectroscopy pilot study for cancerous and normal prostate tissues.
Topics: Collagen; Flavin-Adenine Dinucleotide; Humans; Male; NAD; Pilot Projects; Prostatic Neoplasms; Sensitivity and Specificity; Spectrometry, Fluorescence; Tryptophan | 2012 |
Stokes shift spectroscopic analysis of multifluorophores for human cancer detection in breast and prostate tissues.
Topics: Biomarkers; Breast Neoplasms; Collagen; Female; Humans; Male; NAD; Optical Imaging; Prostatic Neoplasms; ROC Curve; Sensitivity and Specificity; Tryptophan | 2013 |
Large scale dynamics of the Michaelis complex in Bacillus stearothermophilus lactate dehydrogenase revealed by a single-tryptophan mutant study.
Topics: Catalytic Domain; Geobacillus stearothermophilus; Kinetics; L-Lactate Dehydrogenase; Models, Molecular; NAD; Oxamic Acid; Point Mutation; Protein Conformation; Temperature; Tryptophan | 2013 |
Multimodal nonlinear optical microscopy improves the accuracy of early diagnosis of squamous intraepithelial neoplasia.
Topics: Animals; Carcinoma in Situ; Collagen; Cricetinae; Early Diagnosis; Epidermis; Keratins; Mesocricetus; Microscopy; Multivariate Analysis; NAD; Neoplasms, Squamous Cell; Nonlinear Dynamics; Optical Imaging; Tryptophan | 2013 |
Synthesis and application of FePt/CNTs nanocomposite as a sensor and novel amide ligand as a mediator for simultaneous determination of glutathione, nicotinamide adenine dinucleotide and tryptophan.
Topics: Amides; Electrochemical Techniques; Electrodes; Glutathione; Iron; Ligands; Metal Nanoparticles; NAD; Nanotubes, Carbon; Oxidation-Reduction; Platinum; Tryptophan | 2013 |
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Microglia; NAD; Oxidative Stress; Pentosyltransferases; Quinolinic Acid; Temozolomide; Tryptophan; Tryptophan Oxygenase | 2013 |
Investigation of tryptophan-NADH interactions in live human cells using three-photon fluorescence lifetime imaging and Förster resonance energy transfer microscopy.
Topics: Cell Line, Tumor; Cell Nucleus; Cytosol; Diagnostic Imaging; Fluorescence Resonance Energy Transfer; Glucose; HeLa Cells; Humans; Mitochondria; NAD; Optics and Photonics; Photons; Tryptophan | 2013 |
Effect of dietary phytol on the expression of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism, in rats.
Topics: Animals; Body Weight; Carboxy-Lyases; Diet; Eating; Gene Expression Regulation, Enzymologic; Hepatocytes; Male; NAD; Niacin; Organ Size; Phytol; Rats; Rats, Sprague-Dawley; Tryptophan | 2013 |
Native fluorescence spectroscopy reveals spectral differences among prostate cancer cell lines with different risk levels.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Diagnosis, Differential; Humans; Male; Molecular Imaging; NAD; Prostatic Neoplasms; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity; Spectrometry, Fluorescence; Tryptophan | 2013 |
Nicotinamide adenine dinucleotide-induced multimerization of the co-repressor CtBP1 relies on a switching tryptophan.
Topics: Alcohol Oxidoreductases; Amino Acid Motifs; Binding Sites; Cell Line, Tumor; Chromatography, Gel; Cross-Linking Reagents; DNA-Binding Proteins; Fluorescence Resonance Energy Transfer; Gene Expression Regulation, Neoplastic; Humans; Mutagenesis; NAD; Nucleotides; Protein Binding; Protein Multimerization; Protein Structure, Tertiary; Tryptophan; Two-Hybrid System Techniques | 2013 |
Enzymes that control the conversion of L-tryptophan-nicotinamide and the urinary excretion ratio (N(1)-methyl-2-pyridone-5-carboxamide + N(1)-methyl-4-pyridone-3-carboxamide)/N(1)-methylnicotinamide in mice.
Topics: Animals; Body Weight; Eating; Enzymes; Male; Mice; NAD; Niacinamide; Pyridones; Quinolinic Acid; Tryptophan | 2013 |
Biochemical characterization of an L-tryptophan dehydrogenase from the photoautotrophic cyanobacterium Nostoc punctiforme.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Bacterial Proteins; Enzyme Stability; Genes, Bacterial; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Weight; NAD; NADP; Nostoc; Phylogeny; Recombinant Proteins; Sequence Homology, Amino Acid; Stereoisomerism; Substrate Specificity; Temperature; Tryptophan | 2014 |
Regulation of rat hepatic α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme in the tryptophan- NAD pathway, by dietary cholesterol and sterol regulatory element-binding protein-2.
Topics: Animals; Carboxy-Lyases; Cholesterol, Dietary; Gene Expression Regulation, Enzymologic; Hepatocytes; Hydroxycholesterols; Hypercholesterolemia; Liver; Male; Models, Animal; NAD; Rats; Rats, Sprague-Dawley; RNA, Messenger; Simvastatin; Sterol Regulatory Element Binding Protein 2; Tryptophan | 2014 |
Fluorescence spectral diagnosis of malaria: a preliminary study.
Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Female; Flavin-Adenine Dinucleotide; Humans; Malaria; Male; NAD; Porphyrins; Sensitivity and Specificity; Spectrometry, Fluorescence; Tryptophan; Tyrosine; Young Adult | 2014 |
Differences in fluorescence profiles from breast cancer tissues due to changes in relative tryptophan content via energy transfer: tryptophan content correlates with histologic grade and tumor size but not with lymph node metastases.
Topics: Aged; Breast Neoplasms; Case-Control Studies; Female; Humans; Lymph Nodes; Lymphatic Metastasis; Middle Aged; NAD; Optical Imaging; Spectrometry, Fluorescence; Tryptophan | 2014 |
Characterisation of the kynurenine pathway in skin-derived fibroblasts and keratinocytes.
Topics: Cells, Cultured; Chromatography, Gas; Chromatography, High Pressure Liquid; Fibroblasts; Humans; Immunohistochemistry; Interferon-gamma; Keratinocytes; Kynurenine; L-Lactate Dehydrogenase; NAD; Skin; Tryptophan; Ultraviolet Rays | 2015 |
Tryptophan-Dependent Control of Colony Formation After DNA Damage via Sea3-Regulated TORC1 Signaling in Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems; Bleomycin; DNA Damage; DNA Repair; Galactose; Mechanistic Target of Rapamycin Complex 1; Membrane Proteins; Multiprotein Complexes; NAD; Quinolinic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Telomere; TOR Serine-Threonine Kinases; Tryptophan | 2015 |
De-novo NAD+ synthesis regulates SIRT1-FOXO1 apoptotic pathway in response to NQO1 substrates in lung cancer cells.
Topics: A549 Cells; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Forkhead Box Protein O1; Gene Expression Regulation, Neoplastic; Humans; Large Neutral Amino Acid-Transporter 1; Lung Neoplasms; Mice; Mice, Nude; NAD; NAD(P)H Dehydrogenase (Quinone); Neoplasm Transplantation; Oxidative Stress; Oxygen; Signal Transduction; Sirtuin 1; Tryptophan | 2016 |
Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism.
Topics: Cell Cycle; Cell Proliferation; Cells, Cultured; Cellular Senescence; Cluster Analysis; Fibroblasts; Homeostasis; Humans; Intracellular Space; Metabolome; Metabolomics; Models, Biological; NAD; Niacinamide; Oxidation-Reduction; Principal Component Analysis; Tryptophan | 2016 |
Uridine monophosphate synthetase enables eukaryotic
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Multienzyme Complexes; Mutation; NAD; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Quinolinic Acid; Tryptophan | 2017 |
Label-Free Fluorescence Spectroscopy for Detecting Key Biomolecules in Brain Tissue from a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Brain; Disease Models, Animal; Early Diagnosis; Flavin-Adenine Dinucleotide; Humans; Mice; Mice, Transgenic; NAD; Spectrometry, Fluorescence; Tryptophan | 2017 |
Nicotinamide Adenine Dinucleotides Arrest Photoreduction of Class II DNA Photolyases in FADH
Topics: Archaeal Proteins; Deoxyribodipyrimidine Photo-Lyase; Electron Transport; Flavin-Adenine Dinucleotide; Kinetics; Light; Methanosarcina; Molecular Conformation; Mutation; NAD; NADP; Oxidation-Reduction; Tryptophan | 2018 |
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes.
Topics: Animals; Female; HCT116 Cells; Hep G2 Cells; Humans; Intestine, Small; Liver; Mice; Mice, Inbred C57BL; Muscle, Skeletal; NAD; Niacinamide; Poly(ADP-ribose) Polymerases; Sirtuins; Spleen; Tryptophan | 2018 |
A study for the detection of kidney cancer using fluorescence emission spectra and synchronous fluorescence excitation spectra of blood and urine.
Topics: Adult; Biomarkers, Tumor; Female; Flavin-Adenine Dinucleotide; Humans; Kidney Neoplasms; Male; Middle Aged; NAD; Porphyrins; Sensitivity and Specificity; Spectrometry, Fluorescence; Tryptophan | 2018 |
Identification of activation of tryptophan-NAD
Topics: Animals; Biomarkers; Body Weight; Chromatography, Liquid; Cooking; Lipid Metabolism; Liver; Male; Mass Spectrometry; Metabolomics; Mice, Inbred C57BL; NAD; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors; Signal Transduction; Soybean Oil; Triglycerides; Tryptophan | 2018 |
NAD binding by human CD38 analyzed by Trp189 fluorescence.
Topics: ADP-ribosyl Cyclase 1; Binding Sites; HEK293 Cells; Humans; Kinetics; Membrane Glycoproteins; NAD; Tryptophan | 2019 |
Macrophage de novo NAD
Topics: Aging; Animals; Cells, Cultured; Homeostasis; Immunity, Innate; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NAD; Oxidative Phosphorylation; Pentosyltransferases; Phagocytosis; Signal Transduction; Tryptophan | 2019 |
Single-cell redox states analyzed by fluorescence lifetime metrics and tryptophan FRET interaction with NAD(P)H.
Topics: Cytosol; Doxorubicin; Energy Metabolism; Flavin-Adenine Dinucleotide; Fluorescence; Fluorescence Resonance Energy Transfer; HeLa Cells; Humans; Microscopy, Fluorescence, Multiphoton; Mitochondria; NAD; NADP; Optical Imaging; Oxidation-Reduction; Oxidative Phosphorylation; Reactive Oxygen Species; Single-Cell Analysis; Tryptophan | 2019 |
Special Issue on Metabolism Cytometry A.
Topics: Flavin-Adenine Dinucleotide; Flow Cytometry; Humans; NAD; Optical Imaging; Spectrometry, Fluorescence; Tryptophan | 2019 |
Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease.
Topics: Adipose Tissue; Animals; Ataxin-7; Blood Glucose; Energy Metabolism; Humans; Kynurenine; Metabolomics; Mice; Mitochondria; Mitochondrial Diseases; NAD; Neural Stem Cells; Organelles; Peptides; Phenotype; Purkinje Cells; Reproducibility of Results; Spinocerebellar Ataxias; Trinucleotide Repeat Expansion; Tryptophan | 2019 |
GC/MS and LC/MS-based Tissue Metabolomic Analysis Detected Increased Levels of Antioxidant Metabolites in Colorectal Cancer.
Topics: Antioxidants; Chromatography, Liquid; Colorectal Neoplasms; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; NAD; Tryptophan | 2019 |
Increased fatty acid oxidation and mitochondrial proliferation in liver are associated with increased plasma kynurenine metabolites and nicotinamide levels in normolipidemic and carnitine-depleted rats.
Topics: Animals; Carnitine; Cell Proliferation; Kynurenine; Lipid Metabolism; Liver; Male; Metabolic Networks and Pathways; Methylhydrazines; Mitochondria; NAD; Niacinamide; Oxidation-Reduction; Peroxisomes; Rats; Tryptophan | 2020 |
Quinolinate as a Marker for Kynurenine Metabolite Formation and the Unresolved Question of NAD
Topics: Animals; Biomarkers; Cell Movement; Gerbillinae; Hippocampus; HSP90 Heat-Shock Proteins; Immunity; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Pokeweed Mitogens; Poly(ADP-ribose) Polymerases; Quinolinic Acid; Rats; Spleen; Tryptophan | 2020 |
Label-free detection of thalassemia and other ROS impairing diseases.
Topics: Algorithms; Arthritis, Rheumatoid; Humans; Kynurenine; NAD; Oxidative Stress; Principal Component Analysis; Reactive Oxygen Species; ROC Curve; Spectrometry, Fluorescence; Spectrum Analysis, Raman; Thalassemia; Tryptophan | 2020 |
Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway.
Topics: Bacterial Proteins; Binding Sites; Biosynthetic Pathways; Carboxy-Lyases; Catalytic Domain; Crystallography, X-Ray; Diflunisal; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kynurenine; Molecular Docking Simulation; NAD; Pseudomonas fluorescens; Structure-Activity Relationship; Tryptophan | 2021 |
Identifying metastatic ability of prostate cancer cell lines using native fluorescence spectroscopy and machine learning methods.
Topics: Cell Line, Tumor; Humans; Lactic Acid; Machine Learning; Male; NAD; Neoplasm Metastasis; Principal Component Analysis; Prostatic Neoplasms; Reproducibility of Results; ROC Curve; Spectrometry, Fluorescence; Support Vector Machine; Tryptophan | 2021 |
Post deposition aging of bloodstains probed by steady-state fluorescence spectroscopy.
Topics: Blood Chemical Analysis; Blood Stains; Female; Flavins; Humans; Male; NAD; Oxidation-Reduction; Spectrometry, Fluorescence; Time Factors; Tryptophan | 2021 |
Hypoxic preconditioning protects against ischemic kidney injury through the IDO1/kynurenine pathway.
Topics: Animals; Hypoxia; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Ischemia; Kidney; Kynurenine; Metabolome; Mice, Inbred C57BL; Mice, Knockout; NAD; Procollagen-Proline Dioxygenase; Protective Agents; Tryptophan | 2021 |
Cell stress response impairs de novo NAD+ biosynthesis in the kidney.
Topics: Acute Kidney Injury; Animals; Cell Line; Endoplasmic Reticulum Stress; Kidney; Male; Mice; Mice, Inbred C57BL; NAD; Pentosyltransferases; Quinolinic Acid; Tryptophan | 2022 |
Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses.
Topics: Animals; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymphocyte Activation; Mice; NAD; Ovarian Neoplasms; Tryptophan; Tumor Microenvironment | 2022 |
Further characterization of tryptophan metabolism and its dysregulation in fibroids.
Topics: Amino Acid Transport Systems, Neutral; Female; Humans; Kynurenic Acid; Leiomyoma; NAD; RNA, Messenger; Serotonin; Tryptophan | 2022 |
Identification of l-Tryptophan by down-field
Topics: Brain; Deuterium; Humans; Magnetic Resonance Spectroscopy; NAD; Protons; Serotonin; Tryptophan | 2022 |
Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling.
Topics: Adaptor Proteins, Vesicular Transport; ADP-ribosyl Cyclase; Bacteria; Bacterial Proteins; Cyclic ADP-Ribose; Isomerism; NAD; Plant Immunity; Protein Domains; Receptors, Interleukin-1; Signal Transduction; Toll-Like Receptors; Tryptophan | 2022 |
Metabolome-wide association study of the relationship between chlorpyrifos exposure and first trimester serum metabolite levels in pregnant Thai farmworkers.
Topics: Biomarkers; Child; Chlorpyrifos; Creatinine; Cystine; Cytochromes; Farmers; Fatty Acids; Female; Glutathione; Humans; Insecticides; Metabolome; NAD; Niacinamide; Organophosphorus Compounds; Pesticides; Pregnancy; Pregnancy Trimester, First; Reactive Oxygen Species; Thailand; Tryptophan | 2022 |
Metabolomic transition trajectory and potential mechanisms of N-nitrosomethylbenzylamine induced esophageal squamous cell carcinoma in rats.
Topics: Animals; Carcinogens; Carcinogens, Environmental; Cell Transformation, Neoplastic; Dimethylnitrosamine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Metabolome; NAD; Niacin; Niacinamide; Nitrogen; Nitrosamines; Rats; Sphingolipids; Tryptophan; Tumor Microenvironment | 2022 |
Melatonin ameliorates disease severity in a mouse model of multiple sclerosis by modulating the kynurenine pathway.
Topics: Animals; Biological Factors; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Melatonin; Mice; Mice, Inbred C57BL; Multiple Sclerosis; NAD; Nicotinamide N-Methyltransferase; Receptors, Aryl Hydrocarbon; RNA, Messenger; Severity of Illness Index; Tryptophan | 2022 |
Metabolic engineering of Escherichia coli for efficient production of L-5-hydroxytryptophan from glucose.
Topics: 5-Hydroxytryptophan; Escherichia coli; Fermentation; Glucose; Metabolic Engineering; NAD; Neurotransmitter Agents; Serotonin; Tryptophan; Tryptophan Hydroxylase; Xylose | 2022 |
Experimental Clarification of PRPS-1 Structural Essentials.
Topics: Diphosphates; Histidine; Molecular Docking Simulation; NAD; NADP; Nucleotides; Phosphates; Phosphoribosyl Pyrophosphate; Purines; Pyridines; Pyrimidines; Ribose-Phosphate Pyrophosphokinase; Tryptophan | 2022 |
Tryptophan metabolism and disposition in cancer biology and immunotherapy.
Topics: Amino Acid Transport System ASC; Biology; Glucocorticoids; Humans; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Minor Histocompatibility Antigens; NAD; Neoplasms; Serotonin; Sirtuins; Tryptophan | 2022 |
Maternal heterozygosity of Slc6a19 causes metabolic perturbation and congenital NAD deficiency disorder in mice.
Topics: Amino Acid Transport Systems, Neutral; Animals; Congenital Abnormalities; Female; Heterozygote; Kidney; Mice; NAD; Niacinamide; Pregnancy; Tryptophan | 2023 |
The role of the tryptophan-NAD + pathway in a mouse model of severe malnutrition induced liver dysfunction.
Topics: Animals; Liver Diseases; Mice; NAD; Tryptophan | 2022 |
Obesity-Induced Memory Deficits in Female Rats Are Oestrous Cycle Dependent and Linked to Impaired Brain Kynurenine Pathway Metabolism.
Topics: Animals; Brain; Female; Kynurenic Acid; Kynurenine; Memory Disorders; NAD; Obesity; Rats; Tryptophan | 2023 |
Metabolomic analysis shows dysregulation in amino acid and NAD+ metabolism in palmitate treated hepatocytes and plasma of non-alcoholic fatty liver disease spectrum.
Topics: Amino Acids; Hepatocytes; Humans; Kynurenine; Liver; Liver Cirrhosis; NAD; Non-alcoholic Fatty Liver Disease; Palmitates; Palmitic Acid; Tryptophan | 2023 |
A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium.
Topics: Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Humans; Inflammation; Interferon-gamma; Kynurenine; Lung Neoplasms; NAD; Neopterin; Tryptophan | 2023 |
Immunometabolic interference between cancer and COVID-19.
Topics: COVID-19; Humans; Leukocytes, Mononuclear; NAD; Neoplasms; SARS-CoV-2; Tryptophan | 2023 |
Identification of new resonances in downfield
Topics: Humans; Muscle, Skeletal; NAD; Protons; Tryptophan; Water | 2023 |
The kynurenine pathway of tryptophan metabolism: a neglected therapeutic target of COVID-19 pathophysiology and immunotherapy.
Topics: COVID-19; Humans; Immunotherapy; Kynurenine; NAD; Poly(ADP-ribose) Polymerase Inhibitors; SARS-CoV-2; Tryptophan | 2023 |
Hepatocyte nuclear factor 4α mediated quinolinate phosphoribosylltransferase (QPRT) expression in the kidney facilitates resilience against acute kidney injury.
Topics: Acute Kidney Injury; Animals; Hepatocyte Nuclear Factors; Kidney; Mice; NAD; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Quinolinic Acid; Tryptophan | 2023 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |