nad has been researched along with triclosan in 30 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (13.33) | 18.2507 |
2000's | 16 (53.33) | 29.6817 |
2010's | 9 (30.00) | 24.3611 |
2020's | 1 (3.33) | 2.80 |
Authors | Studies |
---|---|
Heath, RJ; Holland, DR; Rock, CO; Rubin, JR; Snow, ME; Zhang, E | 1 |
Kisker, C; Parikh, S; Stewart, MJ; Tonge, PJ; Xiao, G | 1 |
Britton, CJ; Camble, R; Clayton, E; Colls, JG; Hales, NJ; Holdgate, GA; Jude, DA; McLean, EG; Minshull, CA; Mistry, A; Nichols, WW; Pauptit, RA; Rowsell, S; Taylor, IW; Timms, D; Ward, WH | 1 |
Abdel-Meguid, SS; Court, RI; Janson, CA; Payne, DJ; Qiu, X; Smyth, MG | 1 |
Surolia, A; Surolia, N | 1 |
Suguna, K; Surolia, A; Surolia, N | 1 |
Copeland, RA; Jiang, W; Kopcho, LM; Locke, G; Luo, Y; Marcinkeviciene, J | 1 |
Baldock, C; Clough, JM; Levy, CW; Rafferty, JB; Rice, DW; Sedelnikova, S; Slabas, AR; Stuitje, AR; Viner, RC; Wallace, AJ | 1 |
Dar, MJ; Kapoor, M; Surolia, A; Surolia, N | 1 |
Cho, YH; Kim, EJ; Lee, IH; Lee, JK | 1 |
Muralidharan, J; Suguna, K; Surolia, A; Surolia, N | 1 |
McLeod, R; Muench, SP; Prigge, ST; Rafferty, JB; Rice, DW | 1 |
Cui, G; Johnson, F; Novichenok, P; Simmerling, C; Sivaraman, S; Sullivan, TJ; Tonge, PJ | 1 |
Kapoor, M; Mukhi, PL; Suguna, K; Surolia, A; Surolia, N | 1 |
Gopalakrishnapai, J; Kapoor, M; Surolia, A; Surolia, N | 1 |
Kapoor, M; Pidugu, LS; Suguna, K; Surolia, A; Surolia, N | 1 |
Kirisits, MJ; McLeod, R; Muench, SP; Prigge, ST; Rice, DW; Roberts, CW; Wernimont, S; Zhu, L | 1 |
Cheng, X; Cui, G; Rafi, SB; Simmerling, C; Song, K; Tonge, PJ | 1 |
Kirisits, MJ; McLeod, R; Muench, SP; Mui, EJ; Prigge, ST; Rafferty, JB; Rice, DW; Roberts, CW | 1 |
Cai, J; Cai, X; Lorraine Fuller, A; McDougald, LR; Sacchettini, JC; Tan, X; Wang, F; Zhu, G | 1 |
Lu, H; Tonge, PJ | 1 |
Chen, YD; Lu, XY; You, QD | 1 |
Johnson, ME; Mehboob, S; Santarsiero, BD; Truong, K | 1 |
Chi, YM; Lee, JH; Lee, KS; Moon, JH; Park, AK | 1 |
Lindert, S; McCammon, JA | 1 |
Guardado-Calvo, P; Llamas-Saiz, AL; Noël, AJ; Otero, JM; Pingoud, A; Schierling, B; van Raaij, MJ; Wende, W | 1 |
Afanador, GA; Anderson, JW; Cheng, G; Fidock, DA; Fishwick, CW; Fomovska, A; Freire, E; Freundlich, JS; Jacobus, DP; Kozikowski, AP; McLeod, R; McPhillie, M; Muench, SP; Prigge, ST; Rice, DW; Schön, A; Shieh, HM; Stec, J; Zhou, Y | 1 |
Chen, Y; Hong, SJ; Liu, L; Liu, M; Liu, XD; Tang, XG; Xie, QS; Xu, J; Yang, HY; Yang, TT; Yang, YT; Zhao, KJ; Zhou, YQ; Zhu, L | 1 |
Ge, RS; Hu, Z; Li, H; Li, J; Li, X; Shi, L; Tang, Y; Tian, F; Wang, S; Wang, Y; Zhu, Y | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
1 review(s) available for nad and triclosan
Article | Year |
---|---|
Recent progress in the identification and development of InhA direct inhibitors of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Enzyme Inhibitors; Isoniazid; Mycobacterium tuberculosis; NAD; Oxidoreductases; Pyrazoles; Triclosan | 2010 |
29 other study(ies) available for nad and triclosan
Article | Year |
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Mechanism of triclosan inhibition of bacterial fatty acid synthesis.
Topics: Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Models, Molecular; Molecular Structure; Mutation, Missense; NAD; Oxidoreductases; Protein Binding; Triclosan | 1999 |
Structural basis and mechanism of enoyl reductase inhibition by triclosan.
Topics: Anti-Bacterial Agents; Boron Compounds; Crystallography; Drug Resistance, Microbial; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Models, Molecular; NAD; Oxidoreductases; Triclosan | 1999 |
Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan.
Topics: Anti-Infective Agents, Local; Binding, Competitive; Catalysis; Chromatography, Gel; Crystallization; Crystallography, X-Ray; Dose-Response Relationship, Drug; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Kinetics; Mass Spectrometry; Models, Chemical; NAD; Oxidoreductases; Structure-Activity Relationship; Triclosan | 1999 |
Molecular basis for triclosan activity involves a flipping loop in the active site.
Topics: Amino Acid Sequence; Anti-Infective Agents, Local; Binding Sites; Crystallography, X-Ray; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Escherichia coli; Hydrogen Bonding; Isoleucine; Models, Molecular; Molecular Sequence Data; NAD; Oxidoreductases; Protein Conformation; Serine; Triclosan | 1999 |
Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum.
Topics: Amino Acid Sequence; Animals; Antimalarials; Disease Models, Animal; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Malaria; Mice; Mice, Inbred BALB C; Molecular Sequence Data; NAD; Oxidoreductases; Plasmodium berghei; Plasmodium falciparum; Triclosan | 2001 |
Structural basis for triclosan and NAD binding to enoyl-ACP reductase of Plasmodium falciparum.
Topics: Animals; Brassica; Computer Simulation; Drug Design; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Ligands; Models, Chemical; Models, Molecular; NAD; Oxidoreductases; Plasmodium falciparum; Structure-Activity Relationship; Substrate Specificity; Triclosan | 2001 |
Enoyl-ACP reductase (FabI) of Haemophilus influenzae: steady-state kinetic mechanism and inhibition by triclosan and hexachlorophene.
Topics: Binding Sites; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Haemophilus influenzae; Hexachlorophene; Kinetics; Models, Chemical; NAD; Oxidoreductases; Triclosan | 2001 |
A study of the structure-activity relationship for diazaborine inhibition of Escherichia coli enoyl-ACP reductase.
Topics: Binding Sites; Boron Compounds; Crystallography, X-Ray; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Escherichia coli; Models, Molecular; NAD; Oxidoreductases; Protein Binding; Protein Conformation; Protein Subunits; Structure-Activity Relationship; Triclosan | 2001 |
Kinetic determinants of the interaction of enoyl-ACP reductase from Plasmodium falciparum with its substrates and inhibitors.
Topics: Acyl Coenzyme A; Animals; Antimalarials; Cloning, Molecular; Drug Design; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Fatty Acid Synthases; Humans; Kinetics; Malaria, Falciparum; NAD; Oxidoreductases; Plasmodium falciparum; Recombinant Proteins; Substrate Specificity; Triclosan | 2001 |
Characterization of a novel enoyl-acyl carrier protein reductase of diazaborine-resistant Rhodobacter sphaeroides mutant.
Topics: Amino Acid Sequence; Anti-Infective Agents, Local; Bacterial Proteins; Binding Sites; Boron Compounds; Drug Resistance, Bacterial; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oxidoreductases; Point Mutation; Rhodobacter sphaeroides; Sequence Alignment; Triclosan | 2002 |
Exploring the interaction energies for the binding of hydroxydiphenyl ethers to enoyl-acyl carrier protein reductases.
Topics: Animals; Bacillus; Enoyl-(Acyl-Carrier Protein) Reductase (NADPH, B-Specific); Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Fatty Acids; Hexachlorophene; Molecular Structure; NAD; NADP; Oxidoreductases; Phenyl Ethers; Plasmodium falciparum; Protein Conformation; Protozoan Proteins; Staphylococcus aureus; Substrate Specificity; Thermodynamics; Triclosan | 2003 |
Expression, purification and crystallization of the Plasmodium falciparum enoyl reductase.
Topics: Animals; Carrier Proteins; Cloning, Molecular; Crystallization; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Maltose-Binding Proteins; NAD; Oxidoreductases; Plasmodium falciparum; Recombinant Fusion Proteins; Triclosan; X-Ray Diffraction | 2003 |
Inhibition of the bacterial enoyl reductase FabI by triclosan: a structure-reactivity analysis of FabI inhibition by triclosan analogues.
Topics: Anti-Bacterial Agents; Bacteria; Crystallography, X-Ray; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Microbial Sensitivity Tests; Models, Molecular; Mutation; NAD; Oxidoreductases; Protein Binding; Structure-Activity Relationship; Thermodynamics; Triclosan | 2004 |
Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD+.
Topics: Alanine; Animals; Asparagine; Carbon-Carbon Ligases; Cloning, Molecular; Crystallography, X-Ray; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); NAD; Niacinamide; Oxidoreductases; Plasmodium falciparum; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Surface Plasmon Resonance; Triclosan | 2004 |
Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, Gel; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oxidoreductases; Plasmodium falciparum; Protein Structure, Quaternary; Triclosan | 2004 |
Structural basis for the variation in triclosan affinity to enoyl reductases.
Topics: Brassica; Crystallography, X-Ray; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Genetic Variation; Hydrogen Bonding; Models, Molecular; Molecular Structure; NAD; Oxidoreductases; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Substrate Specificity; Triclosan; Water | 2004 |
Expression, purification and preliminary crystallographic analysis of the Toxoplasma gondii enoyl reductase.
Topics: Animals; Antiprotozoal Agents; Crystallization; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); NAD; Protozoan Proteins; Solvents; Toxoplasma; Triclosan; X-Ray Diffraction | 2006 |
Insight through molecular mechanics Poisson-Boltzmann surface area calculations into the binding affinity of triclosan and three analogues for FabI, the E. coli enoyl reductase.
Topics: Binding Sites; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Escherichia coli Proteins; Fatty Acid Synthase, Type II; Hydrogen Bonding; Models, Molecular; NAD; Protein Binding; Quantitative Structure-Activity Relationship; Thermodynamics; Triclosan | 2006 |
Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents.
Topics: Amino Acid Sequence; Animals; Antimalarials; Antiparasitic Agents; Apoenzymes; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Drug Design; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Models, Molecular; Molecular Sequence Data; NAD; Plant Proteins; Plasmodium falciparum; Protein Conformation; Sequence Alignment; Species Specificity; Toxoplasma; Triclosan; Water | 2007 |
Biochemical characterization of enoyl reductase involved in Type II fatty acid synthesis in the intestinal coccidium Eimeria tenella (Phylum Apicomplexa).
Topics: Animals; Cloning, Molecular; Coenzyme A; Coenzymes; DNA, Protozoan; Eimeria tenella; Enzyme Inhibitors; Fatty Acid Desaturases; Gene Expression; Microscopy, Confocal; Molecular Sequence Data; NAD; Organelles; Recombinant Proteins; Sequence Analysis, DNA; Triclosan | 2007 |
Mechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia mallei.
Topics: Bacterial Proteins; Burkholderia mallei; Catalysis; Catalytic Domain; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; NAD; Protein Binding; Substrate Specificity; Triclosan | 2010 |
Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD(+) and triclosan.
Topics: Crystallography, X-Ray; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Francisella tularensis; Models, Molecular; NAD; Protein Binding; Protein Structure, Tertiary; Structural Homology, Protein; Triclosan | 2010 |
Crystallization and preliminary X-ray crystallographic studies of enoyl-acyl carrier protein reductase (FabI) from Psuedomonas aeruginosa.
Topics: Apoenzymes; Bacterial Proteins; Crystallization; Crystallography, X-Ray; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acid Synthases; Molecular Weight; NAD; Pseudomonas aeruginosa; Triclosan; X-Ray Diffraction | 2011 |
Dynamics of Plasmodium falciparum enoyl-ACP reductase and implications on drug discovery.
Topics: Binding Sites; Computer-Aided Design; Drug Discovery; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Hydrogen Bonding; Ligands; Molecular Dynamics Simulation; NAD; Plasmodium falciparum; Protein Binding; Triclosan | 2012 |
High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan.
Topics: Amino Acid Sequence; Apoenzymes; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Stability; Models, Molecular; Molecular Sequence Data; NAD; Protein Binding; Protein Structure, Quaternary; Sequence Alignment; Structural Homology, Protein; Thermus thermophilus; Triclosan | 2012 |
Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.
Topics: Antiprotozoal Agents; Bacterial Proteins; Cell Proliferation; Cells, Cultured; Drug Design; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Fibroblasts; High-Throughput Screening Assays; Hot Temperature; Humans; Inhibitory Concentration 50; Kinetics; Luminescent Proteins; Molecular Conformation; Molecular Docking Simulation; NAD; Oxidation-Reduction; Protein Unfolding; Protozoan Proteins; Recombinant Proteins; Toxoplasma; Triclosan | 2013 |
Characteristics of β-oxidative and reductive metabolism on the acyl side chain of cinnamic acid and its analogues in rats.
Topics: Animals; Cinnamates; Fatty Acids; Hepatocytes; Male; Methacrylates; Microsomes, Liver; Mitochondria, Liver; Molecular Structure; NAD; Oxidation-Reduction; Pyrazines; Rats, Sprague-Dawley; Triclosan | 2019 |
Inhibition of human and rat placental 3β-hydroxysteroid dehydrogenase/Δ
Topics: Animals; Female; Fungicides, Industrial; Humans; Insecticides; Isomerases; Multienzyme Complexes; NAD; Placenta; Pregnancy; Pregnenolone; Rats; Triclosan | 2023 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |