nad has been researched along with tiazofurin in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (38.10) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goto, H; Ogasawara, N; Yamada, Y; Yoshino, M | 1 |
| Natsumeda, Y; Pillwein, K; Weber, G | 1 |
| Ahluwalia, GS; Cooney, DA; Dion, RL; Gebeyehu, G; Jayaram, HN; Johns, DG; Kelley, JA; Marquez, VE; Van Cott, A; Wilson, YA | 1 |
| Kuttan, R; Saunders, P | 1 |
| Berger, NA; Berger, SJ; Catino, DM; Petzold, SJ; Robins, RK | 1 |
| Betts, CR; Cooney, DA; Gebeyehu, G; Jayaram, HN; Johns, DG; Kelley, JA; Marquez, VE | 1 |
| Ahluwalia, GS; Cooney, DA; Dion, RL; Gebeyehu, G; Jayaram, HN; Johns, DG; Kelley, JA; Marquez, VE; Robins, RK | 1 |
| Cooney, DA; Gebeyehu, G; Glazer, RI; Jayaram, HN; Johns, DG; Kelley, JA; Marquez, VE; Van Cott, AC; Zwelling, LA | 1 |
| Faderan, MA; Liepnieks, JJ; Lui, MS; Weber, G | 1 |
| Barzi, A; Cappellacci, L; Carrell, C; Franchetti, P; Goldstein, BM; Grifantini, M; Jayaram, HN; Nocentini, G; O'Connor, A; Yang, H | 1 |
| Alvarez, E; Arimilli, S; Krohn, K; Muhs, MA; Saunders, PP; Surve-lyer, R | 1 |
| Boulton, S; Durkacz, BW; Kyle, S | 1 |
| Digits, JA; Hedstrom, L | 1 |
| Goldstein, BM; Jayaram, HN; Lesiak-Watanabe, K; Pankiewicz, KW; Watanabe, KA | 1 |
| Clark, JL; Lostia, S; Otto, MJ; Pankiewicz, KW; Patterson, SE; Stuyver, LJ; Watanabe, KA | 1 |
| Black, PL; Goldstein, BM; Jayaram, HN; Pankiewicz, KW; Patterson, SE; Risal, D; Schinazi, RF; Stuyver, LJ | 1 |
| Bieganowski, P; Brenner, C | 1 |
| Bennett, EM; Bonnac, L; Chen, L; Felczak, K; Gao, G; Hedstrom, L; Jayaram, HN; Pankiewicz, KW; Patterson, SE; Wilson, D | 1 |
| Aldrich, C; Bennett, E; Cappellacci, L; Chen, L; Di Stefano, M; Felczak, K; Franchetti, P; Grifantini, M; Magni, G; Mazzola, F; Pankiewicz, KW; Petrelli, R; Sham, YY; Wilson, D; Yu, JS | 1 |
| Bell, JE; Goldstein, BM; Marquez, VE | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
1 review(s) available for nad and tiazofurin
| Article | Year |
|---|---|
Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target.
Topics: Catalysis; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Molecular Mimicry; Molecular Structure; Mycophenolic Acid; NAD; Ribavirin; Ribonucleosides | 2004 |
20 other study(ies) available for nad and tiazofurin
| Article | Year |
|---|---|
IMP dehydrogenase and action of antimetabolites in human cultured blast cells.
Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Humans; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Kinetics; Leukemia; NAD; Ribavirin; Ribonucleosides | 1990 |
Targets and markers of selective action of tiazofurin.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Guanine Nucleotides; IMP Dehydrogenase; Liver; Liver Neoplasms, Experimental; NAD; Phosphoribosyl Pyrophosphate; Rats; Rats, Inbred Strains; Ribavirin; Ribonucleosides | 1985 |
Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogues. Synthesis, structure, and interactions with IMP dehydrogenase.
Topics: Animals; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Leukemia P388; Mice; NAD; Organoselenium Compounds; Ribavirin; Ribonucleosides; Selenium | 1985 |
Inhibitors of inosinate dehydrogenase.
Topics: Allosteric Site; Animals; Binding Sites; Binding, Competitive; Cell Line; Cricetinae; Cricetulus; Female; Fibroblasts; IMP Dehydrogenase; Ketone Oxidoreductases; NAD; Ovary; Protein Binding; Ribavirin; Ribonucleotides | 1987 |
Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by the synthetic "C" nucleoside analogs, tiazofurin and selenazofurin. A new strategy for cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Leukemia L1210; Mice; NAD; Nucleoside Diphosphate Sugars; Organoselenium Compounds; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Ribavirin; Ribonucleosides; Selenium | 1985 |
The conversion of 2-beta-D-ribofuranosylthiazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties.
Topics: Adenosine; Animals; Antineoplastic Agents; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Leukemia P388; Male; Mice; NAD; Ribavirin; Ribonucleosides | 1982 |
Conversion of 2-beta-D-ribofuranosylselenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties.
Topics: Animals; Gas Chromatography-Mass Spectrometry; IMP Dehydrogenase; Ketone Oxidoreductases; Leukemia P388; Leukemia, Experimental; Mice; NAD; Organoselenium Compounds; Ribavirin; Ribonucleosides; Selenium | 1983 |
Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity.
Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Guanosine Triphosphate; IMP Dehydrogenase; Ketone Oxidoreductases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; NAD; Ribavirin; Ribonucleosides; Spectrophotometry | 1983 |
Tiazofurin-induced selective depression of NAD content in hepatoma 3924A.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; NAD; Rats; Rats, Inbred ACI; Ribavirin; Ribonucleosides | 1984 |
Furanfurin and thiophenfurin: two novel tiazofurin analogues. Synthesis, structure, antitumor activity, and interactions with inosine monophosphate dehydrogenase.
Topics: Animals; Antineoplastic Agents; Crystallography, X-Ray; Humans; IMP Dehydrogenase; Inosine Monophosphate; Magnetic Resonance Spectroscopy; Mice; NAD; Neoplasms; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured | 1995 |
Metabolism and action of benzamide riboside in Chinese hamster ovary cells.
Topics: Animals; Antineoplastic Agents; CHO Cells; Cricetinae; Drug Resistance; Enzyme Inhibitors; NAD; Nucleosides; Phosphorylation; Ribavirin | 1996 |
Low nicotinamide mononucleotide adenylyltransferase activity in a tiazofurin-resistant cell line: effects on NAD metabolism and DNA repair.
Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Division; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; Nicotinamide-Nucleotide Adenylyltransferase; Ribavirin; Temozolomide | 1997 |
Drug selectivity is determined by coupling across the NAD+ site of IMP dehydrogenase.
Topics: Adenosine Diphosphate; Animals; Cricetinae; Cricetulus; Drug Resistance; Drug Synergism; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Mutagenesis, Site-Directed; Mycophenolic Acid; NAD; Ribavirin; Spectrometry, Fluorescence; Tritrichomonas foetus; Tryptophan | 2000 |
The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside.
Topics: Antineoplastic Agents; Cell Survival; Humans; IMP Dehydrogenase; NAD; Niacinamide; Organoselenium Compounds; Pyridinium Compounds; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured | 2002 |
Inhibitors of the IMPDH enzyme as potential anti-bovine viral diarrhoea virus agents.
Topics: Animals; Cattle; Cell Line; Computer Systems; Culture Media, Conditioned; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Guanosine Triphosphate; IMP Dehydrogenase; Kidney; Molecular Structure; Mycophenolic Acid; NAD; Nucleosides; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; Ribonucleosides; Viral Plaque Assay; Virus Replication | 2002 |
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans.
Topics: Chromosomes, Human, Pair 9; Energy Metabolism; Evolution, Molecular; Fungi; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Humans; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; NAD; Niacinamide; Nucleosides; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pyridinium Compounds; Ribavirin; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid | 2004 |
Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues.
Topics: Adenosine Monophosphate; Antineoplastic Agents; Diphosphonates; Drug Screening Assays, Antitumor; Humans; IMP Dehydrogenase; Isoenzymes; K562 Cells; Models, Molecular; Mycophenolic Acid; NAD; Protein Binding; Ribavirin | 2007 |
Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues.
Topics: Adenosine; Binding Sites; Disulfides; Humans; Models, Molecular; Molecular Conformation; Mycobacterium tuberculosis; NAD; Phosphotransferases (Alcohol Group Acceptor); Ribavirin | 2009 |
Dehydrogenase binding by tiazofurin anabolites.
Topics: Adenine Nucleotides; Antineoplastic Agents; Binding, Competitive; Computer Simulation; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Models, Chemical; Oxidoreductases; Ribavirin; Ribonucleosides | 1990 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |