Compounds > nad
Page last updated: 2024-08-17

nad and temozolomide

nad has been researched along with temozolomide in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's2 (18.18)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Boulton, S; Curtin, NJ; Durkacz, BW; Golding, BT; Griffin, RJ; Pemberton, LC; Porteous, JK1
Boulton, S; Durkacz, BW; Kyle, S1
Almassy, RJ; Boritzki, TJ; Calabrese, CR; Calvert, AH; Canan Koch, SS; Curtin, NJ; Ekker, A; Golding, BT; Griffin, RJ; Hostomsky, Z; Kumpf, RA; Kyle, S; Li, J; Maegley, KA; Mansour, RN; Newell, DR; Thomas, HD; Thoresen, LH; Tikhe, JG; Wang, LZ; Webber, SE; Yu, XH; Zhang, C; Zhang, KE; Zook, SE1
Arris, CA; Calvert, HA; Canan-Koch, S; Curtin, NJ; Durkacz, BW; Hostomsky, Z; Kyle, S; Newell, DR; Wang, LZ; Webber, SE; Yiakouvaki, A1
Brown, AR; Goellner, EM; Grimme, B; Lin, YC; Mitchell, L; Sobol, RW; Sugrue, KF; Tang, JB; Trivedi, RN; Wang, XH1
Adams, S; Ahrendt, T; Bode, HB; Guillemin, GJ; Oezen, I; Opitz, CA; Platten, M; Radlwimmer, B; Sahm, F; von Deimling, A; Wick, W1
Chaumeil, MM; Gaensler, K; Ito, M; Jalbert, LE; Mukherjee, J; Nelson, SJ; Park, I; Pieper, RO; Ronen, SM1
Batchelor, TT; Cahill, DP; Chi, AS; Fisher, DE; Higuchi, F; Iafrate, AJ; Koerner, MVA; Lelic, N; Miller, JJ; Shankar, GM; Tanaka, S; Tateishi, K; Wakimoto, H1
Ikeda, K; Kamada, M; Manome, Y1
Chun, JH; Huang, RCC; Jackson, TLB; Kimura, K; Liang, YC; Lin, YL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1

Other Studies

11 other study(ies) available for nad and temozolomide

ArticleYear
Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors.
    British journal of cancer, 1995, Volume: 72, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Survival; Dacarbazine; DNA Damage; Drug Synergism; Enzyme Inhibitors; Isoquinolines; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Temozolomide

1995
Low nicotinamide mononucleotide adenylyltransferase activity in a tiazofurin-resistant cell line: effects on NAD metabolism and DNA repair.
    British journal of cancer, 1997, Volume: 76, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Division; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; Nicotinamide-Nucleotide Adenylyltransferase; Ribavirin; Temozolomide

1997
Novel tricyclic poly(ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity: design, synthesis, and X-ray cocrystal structure.
    Journal of medicinal chemistry, 2002, Nov-07, Volume: 45, Issue:23

    Topics: Antineoplastic Agents; Crystallography, X-Ray; Dacarbazine; Drug Design; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Humans; Indoles; Isoquinolines; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship; Temozolomide; Topotecan; Tumor Cells, Cultured

2002
Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-01, Volume: 10, Issue:3

    Topics: Adenine; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Azulenes; Base Pair Mismatch; Benzodiazepines; Cell Division; Cell Line, Tumor; Cisplatin; Dacarbazine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Genotype; Guanine; Humans; Models, Chemical; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Temozolomide

2004
Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair.
    Cancer research, 2011, Mar-15, Volume: 71, Issue:6

    Topics: Acrylamides; Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Glioblastoma; Humans; Hydroxylamines; Immunoblotting; Methyl Methanesulfonate; NAD; Piperidines; Poly(ADP-ribose) Polymerases; RNA Interference; Temozolomide

2011
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress.
    Cancer research, 2013, Jun-01, Volume: 73, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Microglia; NAD; Oxidative Stress; Pentosyltransferases; Quinolinic Acid; Temozolomide; Tryptophan; Tryptophan Oxygenase

2013
Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor of temozolomide response in glioblastoma cells.
    Cancer research, 2014, Dec-01, Volume: 74, Issue:23

    Topics: Apoptosis; Biomarkers, Tumor; Carrier Proteins; Cell Line, Tumor; Checkpoint Kinase 1; Dacarbazine; DNA Damage; DNA Repair; Gene Expression; Glioblastoma; Humans; L-Lactate Dehydrogenase; Magnetic Resonance Imaging; Membrane Proteins; Methyltransferases; NAD; Protein Kinases; Pyruvic Acid; Temozolomide; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2014
The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in
    Cancer research, 2017, 08-01, Volume: 77, Issue:15

    Topics: Acrylamides; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Dacarbazine; Enzyme Inhibitors; Female; Glioma; Humans; Isocitrate Dehydrogenase; Mice; Mice, SCID; Mutation; NAD; Nicotinamide Phosphoribosyltransferase; Piperidines; Random Allocation; Stress, Physiological; Temozolomide; Xenograft Model Antitumor Assays

2017
Effect of Phosphoribosyltransferase Down-regulation on Malignant Glioma Cell Characteristics.
    Anticancer research, 2020, Volume: 40, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Proliferation; Cytokines; Down-Regulation; Glioma; Humans; NAD; Nicotinamide Phosphoribosyltransferase; Pentosyltransferases; RNA, Small Interfering; Temozolomide

2020
Tetra-O-methyl-nordihydroguaiaretic acid inhibits energy metabolism and synergistically induces anticancer effects with temozolomide on LN229 glioblastoma tumors implanted in mice while preventing obesity in normal mice that consume high-fat diets.
    PloS one, 2023, Volume: 18, Issue:5

    Topics: Animals; Cell Line, Tumor; Diet, High-Fat; Energy Metabolism; Glioblastoma; Humans; Masoprocol; Mice; NAD; Temozolomide; Tumor Microenvironment

2023
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010