Page last updated: 2024-08-17

nad and pyrazinamide

nad has been researched along with pyrazinamide in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199011 (57.89)18.7374
1990's2 (10.53)18.2507
2000's3 (15.79)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doi, K1
Aoki, N; Inoue, K; Sanada, H; Wada, O1
Abeles, RH; Alston, TA1
Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Yamamoto, T1
Bekierkunst, A; Bricker, A1
Dulin, WE; Wyse, BM1
Toida, I2
Protivinsky, R1
Berger, NA; Berger, SJ; Catino, DM; Sikorski, GW; Sims, JL1
Imai, H; Nasu, S; Sakakibara, S; Ueda, I; Yamaguchi, K1
Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T1
Iwamoto, N; Sano, K; Shin, M; Umezawa, C; Yamashita, M1
Fukuwatari, T; Shibata, K; Sugimoto, E2
Egashira, Y; Sanada, H; Sato, M; Shin, M; Sugawara, R; Tanabe, A1
Attalla, SM; Carter, WG; Christie, D; Elmorsy, E; Fikry, E; Kocon, A; Nwidu, LL; Turner, R; Warren, A1
Dartois, V; Dick, T; Gopal, P; GrĂ¼ber, G; Kaya, F; Manimekalai, MSS; Nartey, W; Ragunathan, P; Sarathy, J; Setzer, C; Yee, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1

Reviews

1 review(s) available for nad and pyrazinamide

ArticleYear
Chemotherapeutics with tuberculostatic action.
    Antibiotics and chemotherapy, 1971, Volume: 17

    Topics: Aminosalicylic Acids; Antitubercular Agents; Catalase; Ethambutol; Ethionamide; Hemin; Humans; Hydrogen Peroxide; Isoniazid; Isonicotinic Acids; Metals; NAD; Pyrazinamide; Structure-Activity Relationship; Thiosemicarbazones

1971

Trials

1 trial(s) available for nad and pyrazinamide

ArticleYear
Xylitol-induced increase in the concentration of oxypurines and its mechanism.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:6

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cytosol; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Inosine; Intestine, Small; Lactates; Lactic Acid; Liver; Male; Middle Aged; NAD; Phosphates; Pyrazinamide; Pyruvates; Pyruvic Acid; Saline Solution, Hypertonic; Serum Albumin; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines; Xylitol

1995

Other Studies

17 other study(ies) available for nad and pyrazinamide

ArticleYear
[Studies on the mechanism of the diabetogenic activity of streptozotocin and on the ability of compounds to block the diabetogenic activity of streptozotocin (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1975, Mar-20, Volume: 51, Issue:3

    Topics: Adenoma, Islet Cell; Amides; Animals; Blood Glucose; Cats; Cystine; Deoxyglucose; Diabetes Mellitus; Dimethylnitrosamine; Fatty Acids, Nonesterified; Glutathione; Guinea Pigs; Insulin; Islets of Langerhans; Male; Mannoheptulose; Mice; NAD; Niacinamide; Nicotinic Acids; Pancreatic Neoplasms; Picolinic Acids; Pyrazinamide; Rabbits; Rats; Streptozocin; Tolbutamide; Uric Acid

1975
Effects of dietary pyrazinamide, tryptophan, or nicotinic acid and gamma-ray irradiation on levels of NAD and NADP in various organs of mice.
    Journal of nutritional science and vitaminology, 1989, Volume: 35, Issue:5

    Topics: Animals; Eating; Female; Gamma Rays; Mice; Mice, Inbred C3H; NAD; NADP; Niacin; Organ Specificity; Pyrazinamide; Thymus Gland; Tryptophan

1989
Substrate specificity of nicotinamide methyltransferase isolated from porcine liver.
    Archives of biochemistry and biophysics, 1988, Feb-01, Volume: 260, Issue:2

    Topics: Animals; Glycerol; Hydrogen-Ion Concentration; Isoquinolines; Liver; Methyltransferases; Molecular Weight; NAD; Niacinamide; Nicotinamide N-Methyltransferase; Pyrazinamide; Pyridines; Quinolines; Substrate Specificity; Sulfhydryl Compounds; Swine; Tetrahydroisoquinolines

1988
In vitro conversion of pyrazinamide into 5-hydroxypyrazinamide and that of pyrazinoic acid into 5-hydroxypyrazinoic acid by xanthine oxidase from human liver.
    Biochemical pharmacology, 1987, Oct-01, Volume: 36, Issue:19

    Topics: Humans; Liver; NAD; Pyrazinamide; Xanthine Oxidase

1987
Studies on the mode of action of isoniazid on mycobacteria.
    Archives of biochemistry and biophysics, 1967, Volume: 122, Issue:2

    Topics: Aminosalicylic Acids; Drug Resistance, Microbial; Hot Temperature; Isoniazid; Mycobacterium tuberculosis; N-Glycosyl Hydrolases; NAD; Pyrazinamide; Streptomycin

1967
Studies on the ability of compounds to block the diabetogenic activity of streptozotocin.
    Diabetes, 1969, Volume: 18, Issue:7

    Topics: Amino Acids; Animals; Diabetes Mellitus; Diaphragm; Diazoxide; Epinephrine; Ethanol; Glucosamine; Glucose; Hyperglycemia; Hypoglycemic Agents; Male; NAD; Niacinamide; Nitroso Compounds; Pyrazinamide; Pyrazines; Pyrazoles; Rats; Tolbutamide

1969
Effect of pyrazinamide on nicotinamide adenine dinucleotide glycohydrolase of tuberculous host.
    The American review of respiratory disease, 1973, Volume: 107, Issue:4

    Topics: Animals; Drug Resistance, Microbial; Isoniazid; Liver; Male; Mice; Mycobacterium Infections; Mycobacterium tuberculosis; N-Glycosyl Hydrolases; NAD; Niacinamide; Pyrazinamide

1973
Effects of cord factor on microsomal enzymes.
    The American review of respiratory disease, 1974, Volume: 110, Issue:5

    Topics: Amidohydrolases; Aminopyrine N-Demethylase; Animals; Cattle; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Depression, Chemical; Disaccharides; Glucose-6-Phosphatase; Glycolipids; Mice; Microsomes, Liver; Mycobacterium tuberculosis; N-Glycosyl Hydrolases; NAD; Proteins; Pyrazinamide; Trehalose

1974
Poly(adenosinediphosphoribose) polymerase inhibitors stimulate unscheduled deoxyribonucleic acid synthesis in normal human lymphocytes.
    Biochemistry, 1982, Apr-13, Volume: 21, Issue:8

    Topics: Benzamides; DNA; DNA Repair; Humans; Lymphocytes; Methylnitronitrosoguanidine; NAD; NAD+ Nucleosidase; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Purines; Pyrazinamide

1982
The effect of pyrazines on the metabolism of tryptophan and nicotinamide adenine dinucleotide in the rat. Evidence of the formation of a potent inhibitor of aminocarboxy-muconate-semialdehyde decarboxylase from pyrazinamide.
    Biochimica et biophysica acta, 1981, Sep-18, Volume: 677, Issue:1

    Topics: Animals; Carboxy-Lyases; Kidney; Liver; Male; NAD; Nicotinic Acids; Poly(ADP-ribose) Polymerases; Pyrazinamide; Pyrazines; Rats; Rats, Inbred Strains; Tryptophan

1981
Pyridine nucleotide levels in liver of rats fed clofibrate- or pyrazinamide-containing diets.
    Biochemical pharmacology, 1998, Feb-01, Volume: 55, Issue:3

    Topics: Animals; Clofibrate; Diet; Female; Hypolipidemic Agents; Liver; Male; NAD; NADP; Pyrazinamide; Rats; Rats, Sprague-Dawley

1998
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:6

    Topics: Animals; Antitubercular Agents; Diet; Eating; Liver; Male; NAD; NADP; Niacin; Pyrazinamide; Quinolinic Acid; Rats; Rats, Wistar; Serotonin; Tryptophan; Weight Gain

2001
Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:7

    Topics: Animals; Antitubercular Agents; Carboxy-Lyases; Diet; Eating; Injections, Intraperitoneal; Kidney; Kynurenic Acid; Liver; Male; NAD; Niacin; Pyrazinamide; Rats; Rats, Wistar; Tryptophan; Weight Gain; Xanthurenates

2002
Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2006, Volume: 76, Issue:3

    Topics: Analysis of Variance; Animals; Antitubercular Agents; Carboxy-Lyases; Clofibrate; Diet, Fat-Restricted; Diet, Protein-Restricted; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hypolipidemic Agents; Kidney; Liver; Male; Models, Animal; NAD; Peroxisome Proliferators; Pyrazinamide; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Tryptophan; Weight Gain

2006
Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics.
    Human & experimental toxicology, 2017, Volume: 36, Issue:6

    Topics: Adenosine Triphosphate; Antitubercular Agents; Drug Interactions; Electron Transport Complex I; Electron Transport Complex III; Energy Metabolism; Hep G2 Cells; Humans; Isoniazid; Lactic Acid; Membrane Potential, Mitochondrial; NAD; Pyrazinamide; Rifampin

2017
Pyrazinoic Acid Inhibits Mycobacterial Coenzyme A Biosynthesis by Binding to Aspartate Decarboxylase PanD.
    ACS infectious diseases, 2017, 11-10, Volume: 3, Issue:11

    Topics: Antitubercular Agents; Binding Sites; Carbon; Carboxy-Lyases; Coenzyme A; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Models, Molecular; Mycobacterium bovis; Mycobacterium tuberculosis; NAD; Protein Binding; Protein Conformation; Pyrazinamide

2017
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010