Compounds > nad

Page last updated: 2024-08-17

nad and o-acetyl-adp-ribose

nad has been researched along with o-acetyl-adp-ribose in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	13 (76.47)	29.6817
2010's	3 (17.65)	24.3611
2020's	1 (5.88)	2.80

Authors

Authors	Studies
Denu, JM; Landry, J; Sternglanz, R; Tanner, KG	1
Moazed, D; Tanny, JC	1
Avalos, J; Boeke, JD; Celic, I; Deng, H; Sauve, AA; Schramm, VL	1
Borra, MT; Denu, JM; Foltz, KR; Jackson, MD; Marshall, B; O'Neill, FJ; Verdin, E	1
Denu, JM; Jackson, MD	1
Sauve, AA; Schramm, VL	1
Borra, MT; Denu, JM; Langer, MR; Slama, JT	1
Kruger, RG; Liou, GG; Moazed, D; Tanny, JC; Walz, T	1
Hothorn, M; Kustatscher, G; Ladurner, AG; Pugieux, C; Scheffzek, K	1
Hoff, KG; Wolberger, C	1
Khan, AN; Lewis, PN	1
Boeke, JD; Sauve, AA; Schramm, VL; Wolberger, C	1
Avalos, JL; Hoff, KG; Sens, K; Wolberger, C	1
Baur, JA	1
Hirschey, MD; Ho, L; Huang, JY; Shimazu, T; Verdin, E	1
Koppetsch, KJ; Perni, RB; Szczepankiewicz, BG	1
Chea, C; Ishiwata-Endo, H; Kato, J; Koike, K; Lee, DY; Moss, J; Yamashita, S	1

Reviews

5 review(s) available for nad and o-acetyl-adp-ribose

Article	Year
SIR2: the biochemical mechanism of NAD(+)-dependent protein deacetylation and ADP-ribosyl enzyme intermediates. Current medicinal chemistry, 2004, Volume: 11, Issue:7 Topics: Acetylation; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Catalysis; Histone Deacetylases; Hydrolysis; Kinetics; Models, Molecular; NAD; Niacinamide; O-Acetyl-ADP-Ribose; Protein Processing, Post-Translational; Protein Structure, Tertiary; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins	2004
The biochemistry of sirtuins. Annual review of biochemistry, 2006, Volume: 75 Topics: ADP Ribose Transferases; Aging; Amino Acid Sequence; Animals; Caloric Restriction; Humans; Molecular Sequence Data; Molecular Structure; Multigene Family; NAD; O-Acetyl-ADP-Ribose; Protein Conformation; Protein Isoforms; Sequence Alignment; Sirtuins	2006
Biochemical effects of SIRT1 activators. Biochimica et biophysica acta, 2010, Volume: 1804, Issue:8 Topics: Animals; Cardiotonic Agents; Energy Metabolism; Enzyme Activation; Heterocyclic Compounds, 4 or More Rings; Humans; Insulin Resistance; Learning; Longevity; Memory; Mice; Models, Biological; NAD; Neoplasms; Niacinamide; O-Acetyl-ADP-Ribose; Resveratrol; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Stilbenes	2010
Mitochondrial sirtuins. Biochimica et biophysica acta, 2010, Volume: 1804, Issue:8 Topics: Acetylation; Animals; Group III Histone Deacetylases; Humans; Mice; Mitochondria; Mitochondrial Proteins; Models, Biological; NAD; O-Acetyl-ADP-Ribose; Sirtuin 3; Sirtuins	2010
ARH Family of ADP-Ribose-Acceptor Hydrolases. Cells, 2022, Nov-30, Volume: 11, Issue:23 Topics: Adenosine Diphosphate Ribose; Animals; Apoptosis Inducing Factor; Arginine; Glycoside Hydrolases; Humans; Hydrogen Peroxide; Hydrolysis; Mice; Mice, Knockout; NAD; O-Acetyl-ADP-Ribose; Poly(ADP-ribose) Polymerase Inhibitors	2022

Other Studies

12 other study(ies) available for nad and o-acetyl-adp-ribose

Article	Year
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose. Proceedings of the National Academy of Sciences of the United States of America, 2000, Dec-19, Volume: 97, Issue:26 Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Histone Deacetylases; Histones; Molecular Sequence Data; Molecular Structure; NAD; O-Acetyl-ADP-Ribose; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Trans-Activators	2000
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product. Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-16, Volume: 98, Issue:2 Topics: Acetylation; Adenosine Diphosphate Ribose; Coenzymes; Fungal Proteins; Gene Expression Regulation, Fungal; Gene Silencing; Histone Deacetylases; Histones; Hydrolysis; Models, Biological; NAD; O-Acetyl-ADP-Ribose; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Trans-Activators	2001
Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions. Biochemistry, 2001, Dec-25, Volume: 40, Issue:51 Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Arabinose; Archaeal Proteins; Bacterial Proteins; Deuterium Oxide; Enzyme Inhibitors; Fungal Proteins; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Isomerism; Kinetics; Molecular Sequence Data; NAD; Nuclear Magnetic Resonance, Biomolecular; O-Acetyl-ADP-Ribose; Oxygen Isotopes; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Sirtuin 2; Sirtuins; Substrate Specificity; Trans-Activators	2001
Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases. The Journal of biological chemistry, 2002, Apr-12, Volume: 277, Issue:15 Topics: Acetylesterase; Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Catalysis; Cell Cycle; Chick Embryo; Drosophila Proteins; Histone Deacetylases; Molecular Sequence Data; NAD; O-Acetyl-ADP-Ribose; Phenotype; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Sirtuin 2; Sirtuins; Trans-Activators	2002
Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases. The Journal of biological chemistry, 2002, May-24, Volume: 277, Issue:21 Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Chromatography, High Pressure Liquid; Histone Deacetylases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; NAD; O-Acetyl-ADP-Ribose; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Trans-Activators	2002
Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases. Biochemistry, 2004, Aug-03, Volume: 43, Issue:30 Topics: Acetylation; Amino Acid Sequence; Catalysis; Dialysis; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Kinetics; Molecular Sequence Data; NAD; O-Acetyl-ADP-Ribose; Peptide Fragments; Protein Binding; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Substrate Specificity	2004
Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation. Cell, 2005, May-20, Volume: 121, Issue:4 Topics: Binding Sites; Histone Deacetylases; Histones; Lysine; Macromolecular Substances; NAD; O-Acetyl-ADP-Ribose; Phosphoglycerate Dehydrogenase; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins	2005
Splicing regulates NAD metabolite binding to histone macroH2A. Nature structural & molecular biology, 2005, Volume: 12, Issue:7 Topics: Alternative Splicing; Amino Acid Sequence; Crystallography; Gene Components; Heterochromatin; Histones; Humans; Models, Molecular; Molecular Sequence Data; NAD; O-Acetyl-ADP-Ribose; Sirtuins	2005
Getting a grip on O-acetyl-ADP-ribose. Nature structural & molecular biology, 2005, Volume: 12, Issue:7 Topics: Gene Silencing; Heterochromatin; Models, Biological; NAD; O-Acetyl-ADP-Ribose; Sirtuins	2005
Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases. The Journal of biological chemistry, 2006, Apr-28, Volume: 281, Issue:17 Topics: Acetylation; Amino Acid Sequence; Binding Sites; Catalysis; Histone Deacetylases; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis; NAD; O-Acetyl-ADP-Ribose; Point Mutation; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Substrate Specificity	2006
Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acetylated peptide. Structure (London, England : 1993), 2006, Volume: 14, Issue:8 Topics: Crystallization; Crystallography, X-Ray; Models, Molecular; Multiprotein Complexes; NAD; O-Acetyl-ADP-Ribose; Peptides; Sirtuins	2006
One-step, nonenzymatic synthesis of O-acetyl-ADP-ribose and analogues from NAD and carboxylates. The Journal of organic chemistry, 2011, Aug-19, Volume: 76, Issue:16 Topics: Amino Acid Sequence; Carboxylic Acids; Histone Deacetylases; Molecular Sequence Data; Molecular Structure; NAD; O-Acetyl-ADP-Ribose; Sirtuin 2; Sirtuins	2011