nad has been researched along with nicotinamide mononucleotide in 305 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 101 (33.11) | 18.7374 |
| 1990's | 22 (7.21) | 18.2507 |
| 2000's | 30 (9.84) | 29.6817 |
| 2010's | 61 (20.00) | 24.3611 |
| 2020's | 91 (29.84) | 2.80 |
| Authors | Studies |
|---|---|
| Claycomb, WC | 1 |
| Brown, A; Cross, DG; Fisher, HF | 1 |
| Bryson, TA; Dunlap, RB; Ellis, PD; Fisher, RR; Williams, TJ; Wisowaty, JC; Zens, AP | 2 |
| Firshein, W; Greene, M | 1 |
| Brady, RO; Brewer, HB; Fishman, PH; Moss, J; Osborne, JC; Vaughan, M | 1 |
| Woolf, JH; Yuan, JH | 1 |
| Greene, KM; Shen, WC; Van Vunakis, H | 1 |
| Mosbach, K | 1 |
| Reisbig, RR; Woody, RW | 1 |
| Goda, K; Ishiguro, I; Kotake, Y; Naito, J; Otsuka, H; Ueda, T | 1 |
| Ceccuzzi, ML; Ricci, C; Sestini, S | 1 |
| Gross, CJ; Henderson, LM | 1 |
| Billen, D; Hellermann, G | 1 |
| Buchwalow, IB; Hartmann, M; Kleschtschinow, WM; Raikhlin, NT; Unger, E | 1 |
| Billen, D; Hellermann, GR; Stallions, DR | 1 |
| Elliott, G; Rechsteiner, M | 1 |
| Billen, D; Hellermann, GR | 1 |
| Lehman, IR; Modrich, P; Panasenko, SM | 1 |
| Braun, AD; Makarova, TG; Mozhenok, TP; Nemchinskaia, VL | 1 |
| Setlow, RB; Waldstein, EA | 1 |
| Hollaway, MR; Osborne, HH | 1 |
| Affonso, OR; Lemos, MF; Mitidieri, E | 1 |
| Jacobson, MK; Lange, RA | 1 |
| Narasinga Rao, BS; Satyanarayana, U | 1 |
| Joppich-Kuhn, R; Luisi, PL | 1 |
| Lohrmann, R; Orgel, LE | 1 |
| Apitz-Castro, R; Bull, HG; Cordes, EH; Ferraz, JP; Ribbi, A | 1 |
| Foster, JW; Kinney, DM; Moat, AG | 1 |
| Arnold, LJ; Kaplan, NO; Lee, CY; Oppenheimer, NJ | 1 |
| Braun, RD; Elving, PJ; Santhanam, KS | 1 |
| Das, K; Dunnill, P; Lilly, MD | 1 |
| Greenfield, NJ | 1 |
| Christ, W; Hensel, W; Rakow, D | 1 |
| Jacomelli, G; Magagnoli, C; Pescaglini, M; Rocchigiani, M; Sestini, S; Simmonds, HA | 1 |
| Hayakawa, T; Iwai, K; Shibata, K; Taguchi, H | 1 |
| Jayaram, HN; Paulik, E; Weber, G | 1 |
| Roth, JR; Zhu, N | 1 |
| Olivera, BM; Roth, JR; Zhu, N | 1 |
| Niven, DF; O'Reilly, T | 3 |
| Imai, T | 4 |
| Fridovich, I; Liochev, S | 1 |
| Durand, P; Langrené, S; Le Goffic, F; Sicsic, S | 1 |
| Brougher, DS; Foster, AC; Okuno, E; Schwarcz, R | 1 |
| Anderson, BM; Imai, T | 1 |
| Foster, JW; Holley-Guthrie, EA; Warren, F | 1 |
| Antonetti, A; Berrod, S; Gauduel, Y; Migus, A; Yamada, N | 1 |
| Foster, JW; Hill, JM; Holley, EA; Spector, MP | 1 |
| Micheli, V; Ricci, C; Sestini, S | 1 |
| Machida, M; Matsuzawa, H; Miyazawa, T; Ohta, T; Yokoyama, S | 1 |
| Kato, T; Lowry, OH | 1 |
| Chaykin, S; Kuwahara, M | 1 |
| Lundquist, R; Olivera, BM | 1 |
| Belavady, B; Khan, L; Rao, PU | 1 |
| Blumenstein, M; Raftery, MA | 1 |
| Catanzarite, V; Rechsteiner, M | 1 |
| Henderson, LM; Lan, SJ; Lin, LF; Richardson, AH | 1 |
| Henderson, LM; Lin, LF | 1 |
| Bonhoeffer, F; Olivera, BM | 1 |
| Scholz, G; Streffer, C | 1 |
| Dürwald, H; Hess, U; Hoffmann- Berling, H | 1 |
| Lehman, IR; Modorich, P | 1 |
| Kasărov, LB; Moat, AG | 1 |
| Burkhalter, A; MacGregor, JT | 1 |
| Glaser, L; Langer, R | 1 |
| Ise, N; Okubo, T | 1 |
| Karkas, JD | 1 |
| Leroi, GE; Patrick, DM; Wilson, JE | 1 |
| Heik, P; Jeck, R; Woenckhaus, C | 1 |
| Jaus, H; Sauermann, G; Siebert, G | 1 |
| Iwai, K; Taguchi, H | 2 |
| Paulus, H; Sarkar, N | 1 |
| Anderson, BM; Yuan, JH | 1 |
| Darr, D; Fridovich, I | 1 |
| Eklund, H; Jones, TA; Samama, JP | 1 |
| Foster, JW; Holley, EA; Mya, S | 1 |
| Christ, W; Coper, H | 1 |
| Foster, JW | 1 |
| Foster, J; Liu, G; Manlapaz-Ramos, P; Olivera, BM | 1 |
| Amos, H; Lively, MK; Lombardi, D; Mandel, KG | 1 |
| Heard, JT; Tritz, GJ | 1 |
| Kameyama, M; Nakamura, S | 1 |
| Behr, A; Gholson, RK; Taguchi, H | 1 |
| Hankes, LV; Wessels, LM; Yeh, YK | 1 |
| McPheat, WL | 1 |
| London, RE; Unkefer, CJ | 1 |
| Baskowsky-Foster, AM; Foster, JW | 1 |
| Niven, DF | 1 |
| Richards, CD; Snell, CR; Snell, PH | 1 |
| Bovalini, L; Ferri, S; Franchi, GG; Martelli, P | 1 |
| Kiyohara, Y; Sano, K; Umezawa, C; Yamada, O | 1 |
| Rupp, WD; Seeberg, E; Strike, P | 1 |
| Cruz, LJ; Hillyard, D; Imperial, JS; Manlapaz-Ramos, P; Olivera, BM; Rechsteiner, M | 1 |
| Hayaishi, O; Ogata, N; Ueda, K | 1 |
| Hassinen, I; Jämsä, T | 1 |
| Baum, CL; Rosenberg, IH; Selhub, J | 1 |
| Guerin, MC; Marchand, J; Torreilles, J | 1 |
| Peters, G; Rodgers, MA | 1 |
| Kuwahara, M | 1 |
| Cheng, W; Roth, J | 1 |
| Amici, A; Emanuelli, M; Magni, G; Raffaelli, N; Ruggieri, S | 1 |
| Setlow, P; Sun, D | 1 |
| Colman, RF; Ozturk, DH; Park, I; Soundar, S | 1 |
| Hove-Jensen, B | 1 |
| Barile, M; Danese, G; Passarella, S; Quagliariello, E | 1 |
| Callis, P; Gryczynski, I; Kierdaszuk, B; Lakowicz, JR; Malak, H | 1 |
| Aghajanian, SA; Engel, PC | 1 |
| Colman, RF | 1 |
| Micheli, V; Sestini, S | 1 |
| Hagen, T; Ziegler, M | 1 |
| Lee, HC; Munshi, C; Sauve, AA; Schramm, VL | 1 |
| Ahvazi, B; Meighen, E; Szittner, R; Vrielink, A; Zhang, L | 1 |
| Kemmer, G; Kraiss, A; Reidl, J; Schlör, S; Schmidt-Brauns, J; Soleva, E | 1 |
| Kissner, R; Koppenol, WH; Prütz, WA; Rüegger, H | 1 |
| Bugg, CW; Huang, F; Yarus, M | 1 |
| Fiske, MJ; Green, BA; Herbert, M; Kemmer, G; Kraiss, A; Reidl, J; Reilly, TJ; Schlör, S; Schmidt-Brauns, J; Smith, A; Zlotnik, GW | 1 |
| Lauhon, CT; Szostak, JW | 1 |
| Liu, R; Visscher, J | 1 |
| Ariyoshi, M; Hirano, T; Ishihara, K; Jingami, H; Morikawa, K; Yamamoto-Katayama, S | 1 |
| Hatori, M; Imai, T | 1 |
| Hisatsune, J; Itogawa, Y; Katunuma, N; Nagahama, M; Nishimura, H; Sakaguchi, Y; Sakurai, J; Tsuge, H | 1 |
| Amici, A; Carnevali, F; Emanuelli, M; Magni, G; Pierella, F; Raffaelli, N | 1 |
| Andersen, C; Benz, R; Blass, J; Hilpert, AK; Kemmer, G; Maier, E; Reidl, J | 1 |
| HANDLER, P; IMSANDE, J | 1 |
| HAYAISHI, O; NISHIZUKA, Y | 1 |
| GHOLSON, RK; HENDERSON, LM; OGASAWARA, N; UEDA, I | 1 |
| Amici, A; Emanuelli, M; Magni, G; Orsomando, G; Raffaelli, N; Ruggieri, S | 1 |
| Shuman, S | 1 |
| Gajiwala, KS; Pinko, C | 1 |
| Ali, TH; Elzainy, TA | 1 |
| Hardeland, R; Leon, J; Manchester, LC; Mayo, JC; Poeggeler, B; Reiter, RJ; Sainz, RM; Tan, DX | 1 |
| Grunwald, SK; Ludden, PW; Ponnuraj, RK; Rubio, LM | 1 |
| Hara, N; Osago, H; Shibata, T; Tsuchiya, M; Yamada, K | 1 |
| Gerdes, SY; Kurnasov, OV; Osterman, AL; Overbeek, R; Polanuyer, B; Shatalin, K; Sloutsky, R; Vonstein, V | 1 |
| Gakière, B; Noctor, G; Queval, G | 1 |
| Hashida, SN; Kawai-Yamada, M; Takahashi, H; Uchimiya, H | 1 |
| Pichersky, E; Wang, G | 1 |
| Dasgupta, B; Garten, A; Imai, S; Kiess, W; Körner, A; Milbrandt, J; Mills, KF; Revollo, JR; Sasaki, Y; Satoh, A; Townsend, RR; Wang, T; Wolberger, C | 1 |
| Imai, S; Mills, KF; Ramsey, KM; Satoh, A | 1 |
| Burgos, ES; Schramm, VL | 1 |
| Graeff, R; Hao, Q; Jiang, H; Kriksunov, IA; Lee, HC; Lin, H; Liu, Q | 1 |
| Lee, JK; Rozenberg, A | 1 |
| Eyobo, Y; Klose, KE; Magni, G; Martynowski, D; Nikolaev, EV; Osterman, AL; Rodionov, DA; Sorci, L; Zhang, H; Zogaj, X | 1 |
| Chiarugi, A; Formentini, L; Moroni, F | 1 |
| Belenky, P; Bogan, KL; Brenner, C; Burant, CF; Evans, C; Kennedy, R; Song, P | 1 |
| Balan, IS; Fiskum, G; Kristian, T | 1 |
| Imai, S | 1 |
| Di Martino, C; Pallotta, ML | 1 |
| Amici, A; Brunetti, L; Di Stefano, M; Galassi, L; Magni, G; Orsomando, G; Ruggieri, S | 1 |
| Chen, X; Liu, Y; Wang, T; Wu, D; Wu, J; Yu, Q; Zhai, Q; Zhou, X | 1 |
| Allegrone, G; Bruzzone, S; Canella, L; Cassani, C; De Flora, A; Garavaglia, S; Mannino, E; Millo, E; Rizzi, M; Sturla, L | 1 |
| Imai, S; Mills, KF; Yoon, MJ; Yoshino, J | 1 |
| Humphries, KM; Kotake, Y; Matsuzaki, S | 1 |
| Ashihara, H; Katahira, R; Mimura, T; Sasamoto, H; Watanabe, S; Yin, Y | 1 |
| Bam, R; Barlogie, B; Epstein, J; Khan, S; Li, X; Ling, W; Usmani, S; van Rhee, F; Venkateshaiah, SU; Yaccoby, S | 1 |
| Birrell, JA; Hirst, J | 1 |
| Bruzzone, S; Caffa, I; De Flora, A; Grozio, A; Nencioni, A; Raffaelli, N; Salis, A; Sociali, G; Soncini, D; Sturla, L | 1 |
| Bell, EL; Fendt, SM; Guarente, L; Keibler, MA; Mayers, JR; Olenchock, BA; Stephanopoulos, G; Vander Heiden, MG; Vokes, NI; Wasylenko, TM | 1 |
| Masumoto, M; Niimi, T; Orita, M; Takeuchi, M; Yamamoto, T; Yokota, H | 1 |
| Ji, D; Lin, X; Liu, W; Liu, Y; Wang, L; Zhang, Y; Zhao, ZK; Zhou, YJ | 1 |
| Shapiro, AB | 1 |
| Byun, J; Ikeda, Y; Oka, S; Sadoshima, J; Yamamoto, T; Zhai, P | 1 |
| Amici, A; Mazzola, F; Orsomando, G; Raffaelli, N; Ruggieri, S; Zamporlini, F | 1 |
| Agarwal, B; Baur, JA; Dávila, A; Davis, JG; Frederick, DW; Michan, S; Nakamaru-Ogiso, E; Puchowicz, MA | 1 |
| Borradaile, NM; Chan, P; Hughes-Large, JM; Pang, DK; Robson, DL; Toma, J | 1 |
| Jiang, WX; Lu, JT; Lu, YB; Tang, C; Wei, EQ; Wu, M; Zhang, WP; Zhang, XQ | 1 |
| Fishman, PS; Kristian, T; Long, AN; Owens, K; Schlappal, AE; Schuh, RA | 1 |
| Kraus, WL | 1 |
| Lavandero, S; López-Crisosto, C; Oyarzún, AP; Parra, V; Pedrozo, Z; Pennanen, C; Sánchez, G; Sotomayor-Flores, C; Troncoso, R; Westermeier, F | 1 |
| Akazawa, H; Kamo, T; Komuro, I; Kudo-Sakamoto, Y; Lee, JK; Naito, AT; Oka, T; Sakata, Y; Shimizu, Y; Suzuki, J; Yabumoto, C; Yagi, H; Yano, M | 1 |
| Bianchi, G; Bruzzone, S; Emionite, L; Magnone, M; Nahimana, A; Nencioni, A; Raffaelli, N; Raffaghello, L; Sociali, G; Sturla, L; Vigliarolo, T; Zamporlini, F | 1 |
| Li, WL; Miao, CY; Wang, SN; Xu, TY | 1 |
| Hu, X; Sakurai, T; Takata, T; Wang, X; Yang, Y | 1 |
| Avelar-González, FJ; Guerrero-Barrera, AL; Jacques, M; Labrie, J; Loera-Muro, A; Oropeza-Navarro, R; Tremblay, YD | 1 |
| Burkholder, TJ; Hsu, CG | 1 |
| Kristian, T; Long, A; Owens, K; Park, JH | 1 |
| Apte, RS; Ban, N; Imai, SI; Kubota, M; Kubota, S; Lin, JB; Nakamura, R; Santeford, A; Sene, A; Tsubota, K; Yoshida, M; Yoshino, J; Zapata, N | 1 |
| Kawamura, T; Mori, N; Shibata, K | 1 |
| Auwerx, J; Boutant, M; Brenner, C; Canela, N; Cantó, C; Joffraud, M; Kulkarni, SS; Migaud, ME; Ras, R; Ratajczak, J; Redpath, P; Rodrigues, M; Trammell, SA; Yanes, O | 1 |
| Amici, A; Mazzola, F; Mozzon, M; Orsomando, G; Raffaelli, N; Ruggieri, S; Ummarino, S; Zamporlini, F | 1 |
| Bathke, J; Becker, K; Brandstädter, C; Burkhardt, A; Fritz-Wolf, K; Jortzik, E; Rahlfs, S | 1 |
| Guan, Y; Hao, CM; Huang, XZ; Shang, D; Wang, SR; Xie, QH; Xu, YY | 1 |
| Guan, YF; Kong, YY; Li, GQ; Miao, CY; Wang, P; Wei, CC | 1 |
| Deng, KY; Guan, XH; Hu, L; Huang, CC; Qian, YS; Wang, LF; Wang, XN; Xiao, YF; Xin, HB | 1 |
| Kimura, M; Miwa, A; Nishiuchi, T; Sato, K; Sawada, Y; Tamaoki, D; Yokota Hirai, M | 1 |
| Djouder, N; Garrido, A | 1 |
| Cheng, MH; Hua, X; Kong, YY; Li, GQ; Miao, CY; Wang, P; Wei, CC; Zheng, SL | 1 |
| Fujioka, H; Liao, X; Sangwung, P; Shen, Y; Zhang, L; Zhang, R; Zhou, L | 1 |
| Garten, A; Gebhardt, R; Gorski, T; Kiess, W; Penke, M; Schuster, S | 1 |
| Hokazono, E; Kawano, M; Kayamori, Y; Konishi, K; Osawa, S; Sakasegawa, SI; Tamura, T; Ueda, S | 1 |
| Baur, JA; Imai, SI; Yoshino, J | 1 |
| Atomi, H; Hachisuka, SI; Sato, T | 1 |
| Baur, JA; Chellappa, K; Davila, A; Liu, L; Migaud, ME; Nakamaru-Ogiso, E; Paolella, LM; Rabinowitz, JD; Redpath, P; Zhang, Z | 1 |
| Bartoli, M; Fuller, J; Jadeja, RN; Jones, MA; Joseph, E; Martin, PM; Powell, FL; Thounaojam, MC | 1 |
| Brookes, PS; Munger, J; Nadtochiy, SM; Nehrke, K; Wang, YT | 1 |
| Baur, JA; Botolin, P; Davila, A; Guan, Y; Mukherjee, S; Sims, CA; Singh, K | 1 |
| Brenner, C; Cambronne, XA; Cohen, MS; Goodman, RH; Liu, HW; Migaud, ME; Schmidt, MS; Smith, CB | 1 |
| Klimova, N; Kristian, T | 1 |
| Chowdhury, S; Haque, S; Mehedi, I; Nahid, NA; Poddar, SK; Sifat, AE | 1 |
| Abell, L; Caudal, A; Lee, CF; Nagana Gowda, GA; Tian, R | 1 |
| Badalzadeh, R; Hosseini, L; Mahmoudi, J; Vafaee, MS | 1 |
| Hasegawa, K | 1 |
| Brooks, J; Burgos, ES; Cohen, SE; Culver, J; Dispagna, M; Falter, R; Gardell, SJ; Hampton Sessions, E; Hirschi, JS; Hopf, M; Kapoor, N; Khan, A; Ma, CT; Petucci, C; Pinkerton, AB; Sergienko, E; Smith, SR; Tanaka, J | 1 |
| Chondronikola, M; Franczyk, MP; Gunawardana, SC; Klein, S; Piston, DW; Porter, LC; Qi, N; Rensing, N; Sasaki, Y; Stromsdorfer, KL; Wong, M; Wozniak, DF; Yamaguchi, S; Yoshino, J | 1 |
| Black, WB; Cui, Y; Fong, B; King, E; Li, H; Mak, WS; Maxel, S; Sanchez Martinez, A; Siegel, JB; Zhang, L | 1 |
| Fu, Z; Li, Z; Shen, Q; Xiao, Q; Xie, X; Xiong, Z; Yu, C; Zhou, J | 1 |
| Fearnow, A; Klimova, N; Kristian, T; Long, A | 1 |
| Braidy, N; Liu, Y | 1 |
| Deterding, LJ; Fan, W; Kabanov, AV; Lee, E; Li, JL; Li, L; Li, W; Li, X; Lih, FB; Lim, C; Liu, J; Locasale, JW; Makarov, MV; Migaud, ME; Randall, TA; Shats, I; Sokolsky, M; Williams, JG; Wu, X; Xu, X | 1 |
| Guskov, A; Jaehme, M; Singh, R; Slotboom, DJ; Stetsenko, A | 1 |
| Choi, JY; Kang, BE; Ryu, D; Stein, S | 1 |
| Brenner, C; Schmidt, MS | 1 |
| Bruzzone, S; Grozio, A; Imai, SI; Lei, HC; Migaud, M; Mills, K; Sasaki, Y; Sociali, G; Tokizane, K; Yoshino, J | 1 |
| Aspacio, D; Bever, D; Black, WB; King, E; Li, H; Zhang, L | 1 |
| Cui, Z; Gao, Q; Miao, Y; Rui, R; Xiong, B | 1 |
| Bai, X; Bratkowski, M; Brown, SP; Burdett, TC; Cantor, A; Danao, J; Danko, G; Kozak, JA; Lad, S; Mathur, P; Sambashivan, S; Thayer, DA; Xie, T; Yang, YS | 1 |
| Xia, J; Xu, B; Zhao, N | 1 |
| Agorrody, G; Baker, DJ; Baur, JA; Chellappa, K; Childs, BG; Chini, CCS; Chini, EN; Clarke, S; Dang, K; De Cecco, M; de Oliveira, GC; Espindola-Netto, JM; Gomez, LS; Hogan, KA; Jankowski, C; Kanamori, KS; Kashyap, S; Kirkland, AL; Kirkland, JL; McReynolds, MR; Peclat, TR; Puranik, AS; Rabinowitz, JD; Sedivy, JM; Tarragó, MG; Tchkonia, T; Thompson, KL; van Deursen, JM; van Schooten, W; Vidal, P; Warner, GM; Witte, MA | 1 |
| Ishii, J; Kondo, A; Makino, H; Shoji, S; Yamaji, T | 1 |
| Amorim, JA; Barbisan, P; Chen, X; Iesato, Y; Ishihara, K; Lee, JJ; Lu, L; Moustafa, GA; Sinclair, DA; Togka, KA; Ueta, T; Vavvas, DG; Yu, Z | 1 |
| Khodorkovskiy, M; Kropotov, A; Kulikova, V; Migaud, ME; Nerinovski, K; Nikiforov, A; Solovjeva, L; Sudnitsyna, J; Svetlova, M; Yakimov, A; Ziegler, M | 1 |
| Deng, H; Li, T; Liu, X; Liu, Y; Luo, C; Zhang, W; Zong, Z | 1 |
| Hasegawa, K; Itoh, H; Kanda, T; Kawaguchi, T; Kusahana, E; Muraoka, H; Ono, T; Sakamaki, Y; Tokuyama, H; Wakino, S; Yasuda, I | 1 |
| Bao, J; Chen, C; Dai, J; He, Y; Hu, G; Husain, SZ; Jiang, M; Li, B; Li, L; Niu, M; Wen, L; Wu, Z; Zhang, X | 1 |
| Chatton, JY; Gallart-Ayala, H; Ivanisevic, J; Maillard, V; Rosenberg, N; Teav, T; van der Velpen, V | 1 |
| Franczyk, MP; Imai, SI; Kayser, BD; Klein, S; Mills, KF; Patterson, BW; Patti, GJ; Pietka, T; Sindelar, M; Yoshino, J; Yoshino, M | 1 |
| Hao, X; Hu, M; Liao, B; Wang, D; Zhang, X; Zhao, Y | 1 |
| Liu, Y; Yasawong, M; Yu, B | 1 |
| Gibb, Z; Grupen, CG; Hawdon, A; Pollard, CL; Swegen, A | 1 |
| Fischer-Posovszky, P; Roos, J; Zinngrebe, J | 1 |
| Chen, LM; Guo, ZY; Li, C; Liu, XQ; Meng, CX; Wang, ZM; Yan, Y; Yang, H; Yi, H; Zhang, D; Zhao, JY | 1 |
| Chai, H; Chen, Y; Cheng, Y; Liu, X; Wei, Z | 1 |
| Okumura, K; Takeda, K | 1 |
| Cheng, DY; Peng, F; Shen, Q; Xue, YP; Xue, YZ; Zhang, SJ; Zheng, YG | 1 |
| Kim, BS; Maharjan, A; Singhvi, M | 1 |
| Kang, D; Nomiyama, T; Setoyama, D; Yasukawa, T | 1 |
| Asalla, S; Desai, T; Ghadieh, HE; Ghanem, SS; Giacca, A; Ivovic, A; Jentz, EM; Joseph, JW; Joseph, YD; Mori, Y; Muturi, HT; Nahle, A; Najjar, SM; Pereira, S; Poon, F | 1 |
| Bessert, D; Damschroder, D; Greenberg, ML; Ji, J; Lazcano, P; Reynolds, CA; Wessells, R | 1 |
| Li, D; Liu, X; Liu, Z; Niu, Y; Shen, C; Song, Y; Zang, Y; Zhang, B; Zhang, W | 1 |
| Beleva, YM; Bhasin, S; Cheng, M; Dos Santos, M; Lavu, S; Livingston, D; Pencina, KM | 1 |
| Bertoldo, MJ; Campbell, JM; Gilchrist, RB; Goldys, EM; Goss, DM; Habibalahi, A; Ledger, WL; Mahbub, SB; Wu, LE | 1 |
| Homma, K; Irie, J; Itoh, H; Kosugi, S; Miyashita, K; Nagahisa, T; Yamaguchi, S; Yoshino, J | 1 |
| Gibb, Z; Grupen, CG; Pollard, CL; Swegen, A; Younan, A | 1 |
| Jantama, K; Kamkaew, A; Khunnonkwao, P; Lai, RY; Lasin, P; Ngivprom, U; Worakaensai, S | 1 |
| Lalam, SK; Soma, M | 1 |
| Li, J; Lu, J; Nadeeshani, H; Ying, T; Zhang, B | 1 |
| Dong, X; Guan, YF; Hong, C; Hu, WJ; Miao, CY; Qi, Q; Wang, DS; Zhang, C; Zheng, SL | 1 |
| Chen, Y; Deng, H; Ding, W; Liu, X; Luo, C; Zhu, S | 1 |
| Kothari, D; Li, Y; Liang, J; Niu, K; Ru, M; Wang, R; Wang, W; Wu, X; Zhai, Z | 1 |
| Dong, Z; Gao, L; Guo, X; Li, C; Li, M; Li, S; Li, T; Liang, X; Ma, C; Sun, R; Tan, S; Tian, P; Wang, T; Wang, Y; Wu, Z; Yamagata, K; Yan, L; Yan, Y; Yue, X; Zhang, Y | 1 |
| Cai, W; Hu, C; Li, T; Ren, C; Shen, T; Wu, Y; Yu, D; Yu, J; Zou, A | 1 |
| Cao, Y; Li, D; Li, J; Liu, N; Luo, Y; Niu, K; Qiu, J; Wang, H; You, Y; Zhang, Y; Zhu, Z | 1 |
| Campbell, JM | 1 |
| Auchus, RJ; Braun, RT; Breynaert, E; Casalino, LP; Chandran, CV; Chauvin, JR; De Man, WL; Delcour, JA; Ding, S; He, L; Huang, X; Huang, Z; Im, SC; Jung, HY; Khodade, VS; Krishnarjuna, B; Li, L; Li, N; Li, Q; Marte, J; Martens, JA; Myslinski, Z; Pratt, DA; Radhakrishnan, S; Ramamoorthy, A; Ravula, T; Rodriguez, D; Song, L; Toscano, JP; Unruh, MA; Wang, X; Wang, Z; Wouters, AGB; Wu, Z; Yu, S; Zhang, T; Zhang, W; Zhou, J | 1 |
| Fukamizu, Y; Kosaka, H; Sakurai, T; Sato, T; Shigekawa, A; Uchida, Y | 1 |
| Bian, J; Dunstan, CR; Jiang, L; Jiang, X; Lesani, P; Li, N; Li, Y; Lu, Z; Luo, D; Wang, G; Ye, Y; Zhang, W; Zreiqat, H | 1 |
| Aflatounian, A; Bertoldo, MJ; Cochran, BJ; Edwards, MC; Gilchrist, RB; Ledger, WL; Paris, VR; Richani, D; Walters, KA; Wu, LE | 1 |
| Li, Q; Meng, D; You, C | 1 |
| Kong, LH; Liu, TY; Qin, JY; Xu, WN; Yao, QS; Zhang, XH | 1 |
| Gvaramiya, IA; Gvozdik, TE; Karal-Ogly, DD; Keburiya, VV; Klots, IN; Mukhametzyanova, EI; Shamsutdinova, OA | 1 |
| Borrelli, M; Kahn, B; Libby, T | 1 |
| Chen, H; Geng, XL; Li, GQ; Li, L; Li, ZB; Liu, LW; Lu, TQ; Shang, LR; Sui, YH; Sun, B; Wang, YW; Xie, Y; Xue, DB; Yang, WB; Zhang, T; Zhang, YY; Zhao, ZJ | 1 |
| Campelj, D; Philp, A | 1 |
| Chen, Y; Deng, H; Liu, C; Liu, X; Ma, Y; Wang, Q; Wang, W; Yi, M | 1 |
| Katayoshi, T; Kitajima, N; Nakajo, T; Tsuji-Naito, K; Yamaura, N | 1 |
| Akasaka, H; Asano, K; Fujimoto, T; Hara, C; Imai, SI; Kanou, M; Minami, T; Nakagami, H; Nishida, K; Rakugi, H; Shiraki, A; Sugimoto, K; Yamamoto, K; Yamana, K; Yasunobe, Y | 1 |
| Angeletti, C; Cialabrini, L; Coleman, MP; Gasparrini, M; Gilley, J; Kocia, M; Llobet Rosell, A; Loreto, A; Neukomm, LJ; Orsomando, G; Paglione, M; Perillo, G; Raffaelli, N; Wu, PH | 1 |
| Andhalkar, N; Avhad, G; Kumbhar, V; Lin, Z; Maier, AB; Pendse, S; Tao, R; Thasma, S; Vaidya, A; Yi, L | 1 |
| Braidy, N; Helman, T | 1 |
| Abudupataer, M; Lai, H; Li, J; Ming, Y; Wang, C; Xiang, B; Yin, X; Zhu, K | 1 |
| Chabloz, S; Ewald, CY; Lapides, RA; Roider, E; Sharma, A | 1 |
| Apte, RS; Bhargava, A; Bhasin, S; Cheng, M; Ghattas-Puylara, C; Latham, N; Lavu, S; Lawney, B; Lin, AP; Livingston, D; Memish-Beleva, Y; Merugumala, S; Orkaby, AR; Ozimek, NE; Pencina, KM; Reid, KF; Sinclair, DA; Storer, T; Swain, PM; Valderrabano, R; Wilson, L; Wipper, B | 1 |
| Han, W; Li, Z; Liu, C; Liu, H; Zhu, S | 1 |
| Tian, D; Wang, H; Wang, M; Xi, P; Zhang, Y; Zhu, W | 1 |
| Chen, Y; Huang, J; Ke, C; Tao, Y; Yang, X; Zhou, C | 1 |
| Cheng, J; Liu, R; Ma, H; Yu, J; Zhao, Y; Zhu, X | 1 |
| Li, J; Li, Y; Sun, S; Tan, M; Xiang, S; Zhang, X; Zhou, C | 1 |
| Duan, R; Gao, M; Hu, X; Li, Y; Wang, Y; Zeng, J; Zhang, R | 1 |
| Craighead, DH; Freeberg, KA; Martens, CR; Seals, DR; Udovich, CC | 1 |
| Acharjee, A; Anderson, DG; Astuti, D; Barrett, T; Buganim, Y; Cartwright, D; Chipara, M; Cohen, MA; Frickel, EM; Gsponer, J; Huerta-Uribe, A; Hughes, GW; Jaenisch, R; Kataura, T; Kauffman, KJ; Korolchuk, VI; Korsgen, ME; Kuechler, ER; Lara-Reyna, S; Lavery, GG; Maddocks, ODK; Otten, EG; Palhegyi, AM; Panda, PK; Roberts, J; Rosenstock, TR; Sahay, G; Sarkar, S; Sedlackova, L; Seranova, E; Silva, LFSE; Sun, C; Tennant, DA; Torresi, J; Trushin, S; Trushina, E; Wang, H; Ward, C; Zatyka, M; Zhang, S | 1 |
| Dou, Y; He, B; Huang, Y; Yang, B; Yang, X; Zhang, K; Zhang, X | 1 |
| Deng, XM; Li, HR; Li, P; Liu, Q; Sun, CY; Sun, XY; Wang, JF; Yu, CM; Zhu, CL | 1 |
| Borén, J; Doganay, HL; Jin, H; Li, X; Mardinoglu, A; Nielsen, J; Ozturk, G; Turkez, H; Uhlén, M; Yang, H; Zhang, C | 1 |
| Alegre, GFS; Pastore, GM | 1 |
| Bamba, T; Imai, M; Uchiyama, S; Yamane, T | 1 |
| Gong, JS; Liu, Y; Marshall, G; Shi, JS; Su, C; Xu, ZH | 1 |
| Kang, S; Rathmann, A; Sauve, AA; Wang, Q; Yang, Y; Zhang, N | 1 |
| Chalmers, TJ; Das, A; Kim, LJ; Li, C; Madawala, R; Poon, EWK; Quek, LE; Sinclair, DA; Smith, GC; Tucker, SP; Wang, J; Wu, LE | 1 |
| Imamura, H; Kitano, H; Kratz, A; Nishino, T; Sano, H; Shimizu, N; Yachie, A; Yoshida, Y | 1 |
| Bifulco, E; Ferrario, E; Houry, D; Kursula, P; Niere, M; Raasakka, A; Ziegler, M | 1 |
| Chen, L; Chen, M; Hou, Y; Hu, M; Liu, R; Luan, J; Wang, P; Yu, Q | 1 |
| Chonchol, M; Freeberg, KA; Ludwig, KR; Rossman, MJ; Seals, DR | 1 |
| Icso, JD; Thompson, PR | 1 |
| Abe, C; Do, Y; Fukahori, Y; Hirai, H; Kang, D; Miki, K; Nabeshima, YI; Setoyama, D; Toshima, T; Uchiumi, T; Yagi, M | 1 |
| Guan, X; Jiang, G; Pang, T; Tang, L; Xie, L; Zhao, N; Zhu, X | 1 |
| Goswami, L; Kafle, SR; Kim, BS; Kushwaha, A; Maharjan, A | 1 |
| Cao, T; Ding, W; Fan, GC; Ji, X; Ni, R; Peng, T; Zhang, Z | 1 |
| Bell, JE; Goldstein, BM; Marquez, VE | 1 |
| Abell, C; Blundell, TL; Ciulli, A; Smith, AG; Williams, G | 1 |
28 review(s) available for nad and nicotinamide mononucleotide
| Article | Year |
|---|---|
Immobilized coenzymes in general ligand affinity chromatography and their use as active coenzymes.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Affinity; Coenzyme A; Coenzymes; Drug Stability; Enzymes; Isoenzymes; Ligands; NAD; NADP; Nicotinamide Mononucleotide; Protein Binding; Structure-Activity Relationship | 1978 |
Significance of V-factor dependency in the taxonomy of Haemophilus species and related organisms.
Topics: Actinobacillus; Haemophilus; NAD; Niacinamide; Nicotinamide Mononucleotide; Pasteurella; Pasteurellaceae; Pyridines; Pyridinium Compounds; Structure-Activity Relationship | 1990 |
Structure and function of nicotinamide mononucleotide adenylyltransferase.
Topics: Adenosine Triphosphate; Animals; Catalysis; Histone Deacetylases; Humans; Kinetics; Models, Biological; Models, Molecular; Molecular Structure; NAD; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Protein Structure, Tertiary; Silent Information Regulator Proteins, Saccharomyces cerevisiae | 2004 |
NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions.
Topics: Amino Acid Sequence; Cell Compartmentation; Molecular Sequence Data; NAD; NADP; Nicotinamide Mononucleotide; Oxidation-Reduction; Plants; Quinolinic Acid; Sequence Homology, Amino Acid | 2006 |
A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis.
Topics: Aging; Animals; Drug Design; Enzyme Activation; Flavonoids; Humans; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Phenols; Polyphenols; Sirtuins; Small Molecule Libraries | 2010 |
Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis.
Topics: Aging; Animals; Humans; NAD; Nervous System Diseases; Neurogenesis; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase | 2016 |
NAD
Topics: Aging; Humans; Incidence; Life Expectancy; Longevity; NAD; Neoplasms; Niacinamide; Nicotinamide Mononucleotide; Vitamin B Complex | 2017 |
NAD
Topics: Aging; Animals; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds | 2018 |
Multi-targeted Effect of Nicotinamide Mononucleotide on Brain Bioenergetic Metabolism.
Topics: Animals; Brain; Humans; Hydrolases; Mitochondria; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Mononucleotide | 2019 |
Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule.
Topics: Alzheimer Disease; Animals; Cardiovascular Diseases; Diabetes Mellitus; Humans; NAD; Nicotinamide Mononucleotide; Obesity | 2019 |
Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditions.
Topics: Aging; Drug Discovery; Humans; Ischemia; Mitochondria; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds | 2019 |
Novel tubular-glomerular interplay in diabetic kidney disease mediated by sirtuin 1, nicotinamide mononucleotide, and nicotinamide adenine dinucleotide Oshima Award Address 2017.
Topics: Animals; Awards and Prizes; Claudin-1; Diabetic Nephropathies; Epigenesis, Genetic; Gene Expression Regulation; Glucose Transporter Type 2; Humans; Kidney Glomerulus; Kidney Tubules; NAD; Nicotinamide Mononucleotide; Signal Transduction; Sirtuin 1; Sodium-Glucose Transporter 2 | 2019 |
NAD
Topics: Animals; Brain Ischemia; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; NAD; Neurons; Nicotinamide Mononucleotide; Reactive Oxygen Species; Sirtuin 3 | 2020 |
NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis.
Topics: Aging; Animals; Humans; Inflammation; Mice; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Mononucleotide; Oxidative Stress; Pyridinium Compounds; Rats; Risk Assessment | 2020 |
Implications of NAD
Topics: ADP-ribosyl Cyclase; Aging; Animals; Biosynthetic Pathways; Carboxy-Lyases; Clinical Trials as Topic; Enzyme Inhibitors; Gastrointestinal Microbiome; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Probiotics; Pyridinium Compounds; Sirtuins; Translational Research, Biomedical | 2020 |
Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?
Topics: Aging; Dietary Supplements; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide | 2021 |
Biological synthesis of nicotinamide mononucleotide.
Topics: Adenosine; Adenosine Triphosphate; Aging; Cytokines; Humans; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nucleotides; Ribose; Xylose | 2021 |
The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions.
Topics: Aging; Animals; Chronic Disease; Humans; Longevity; Mice; NAD; Nicotinamide Mononucleotide | 2022 |
Nicotinamide mononucleotide (NMN) as an anti-aging health product - Promises and safety concerns.
Topics: Aged; Aging; Cognitive Dysfunction; Humans; Longevity; NAD; Nicotinamide Mononucleotide | 2022 |
Supplementation with NAD
Topics: Animals; Cognitive Dysfunction; Dietary Supplements; Humans; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide | 2022 |
A Narrative Review of Nicotinamide Adenine Dinucleotide (NAD)+ Intermediates Nicotinamide Riboside and Nicotinamide Mononucleotide for Keratinocyte Carcinoma Risk Reduction.
Topics: Carcinoma; Humans; Keratinocytes; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Risk Reduction Behavior | 2022 |
NAD
Topics: Animals; Exercise; Humans; Muscle, Skeletal; NAD; Nicotinamide Mononucleotide | 2022 |
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders.
Topics: Aging; Dietary Supplements; Humans; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Mononucleotide | 2023 |
Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan.
Topics: Adolescent; Dietary Supplements; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotides; Senotherapeutics; Sirtuin 1 | 2023 |
[Advances in physiological activities and synthesis of β-nicotinamide mononucleotide].
Topics: NAD; Nicotinamide Mononucleotide | 2023 |
Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions.
Topics: Aged; Aging; Dietary Supplements; Humans; NAD; Nicotinamide Mononucleotide; Obesity | 2023 |
NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health.
Topics: Diet; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide | 2023 |
Technology and functional insights into the nicotinamide mononucleotide for human health.
Topics: Aging; Humans; NAD; Nicotinamide Mononucleotide; Technology | 2023 |
8 trial(s) available for nad and nicotinamide mononucleotide
| Article | Year |
|---|---|
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.
Topics: Aged; Body Composition; Dietary Supplements; Double-Blind Method; Female; Humans; Insulin; Insulin Resistance; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; NAD; Nicotinamide Mononucleotide; Obesity; Overweight; Postmenopause; Prediabetic State; RNA-Seq; Signal Transduction | 2021 |
Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study.
Topics: Adult; Bicycling; Body Composition; Dietary Supplements; Double-Blind Method; Exercise Test; Exercise Tolerance; Female; Heart Rate; Humans; Male; Middle Aged; Muscle, Skeletal; NAD; Nicotinamide Mononucleotide; Oxygen Consumption; Physical Conditioning, Human; Placebos; Running; Time Factors | 2021 |
MIB-626, an Oral Formulation of a Microcrystalline Unique Polymorph of β-Nicotinamide Mononucleotide, Increases Circulating Nicotinamide Adenine Dinucleotide and its Metabolome in Middle-Aged and Older Adults.
Topics: Aged; Body Mass Index; Humans; Mass Spectrometry; Metabolome; Middle Aged; NAD; Nicotinamide Mononucleotide | 2023 |
Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women.
Topics: Administration, Oral; Adult; Aged; Female; Humans; Male; Middle Aged; NAD; Nicotinamide Mononucleotide; Young Adult | 2022 |
Effects of nicotinamide mononucleotide on older patients with diabetes and impaired physical performance: A prospective, placebo-controlled, double-blind study.
Topics: Animals; Diabetes Mellitus; Double-Blind Method; Male; NAD; Nicotinamide Mononucleotide; Prospective Studies | 2023 |
The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.
Topics: Animals; Dietary Supplements; Double-Blind Method; Humans; Middle Aged; NAD; Nicotinamide Mononucleotide; Treatment Outcome | 2023 |
Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study.
Topics: Aged; Body Weight; Cholesterol; Humans; Insulin Resistance; Middle Aged; NAD; Nicotinamide Mononucleotide; Obesity; Overweight | 2023 |
The acute effect of different NAD
Topics: Humans; Metabolic Diseases; NAD; Neurodegenerative Diseases; Niacin; Niacinamide; Nicotinamide Mononucleotide | 2023 |
269 other study(ies) available for nad and nicotinamide mononucleotide
| Article | Year |
|---|---|
Inhibition of DNA synthesis in differentiating cardiac muscle by NAD.
Topics: Animals; Animals, Newborn; Biological Transport, Active; Cell Differentiation; DNA Replication; Female; Heart; Kinetics; Male; Myocardium; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Pregnancy; Rats; Thymidine | 1976 |
Hydrogen exchange at the amide group of reduced pyridine nucleotides and the inhibition of that reaction by dehydrogenases.
Topics: Alcohol Oxidoreductases; Animals; Cattle; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Liver; NAD; NADP; Nicotinamide Mononucleotide; Oxidation-Reduction; Protein Binding; Ribonucleotides; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet | 1976 |
Nuclear magnetic resonance studies on pyridine dinucleotides. The pH dependence of the carbon-13 nuclear magnetic resonance of NAD+ analogs.
Topics: Adenosine Monophosphate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Conformation; NAD; NADP; Nicotinamide Mononucleotide; Structure-Activity Relationship | 1976 |
Role of deoxyribonucleic acid ligase in a doxyribonucleic acid membrane fraction extracted from pneumococci.
Topics: Adenosine Triphosphate; Cell-Free System; Deoxyribonucleases; DNA Nucleotidyltransferases; DNA, Bacterial; NAD; Nicotinamide Mononucleotide; Nucleotides; Phosphotransferases; Polynucleotide Ligases; Streptococcus pneumoniae; Subcellular Fractions | 1976 |
Effect of gangliosides and substrate analogues on the hydrolysis of nicotinamide adenine dinucleotide by choleragen.
Topics: Adenine; Adenine Nucleotides; Bacterial Toxins; Gangliosides; NAD; NAD+ Nucleosidase; NADP; Niacinamide; Nicotinamide Mononucleotide; Protein Conformation; Spectrometry, Fluorescence; Structure-Activity Relationship; Vibrio cholerae | 1977 |
Studies of yeast alcohol dehydrogenase with 3-aminopyridine monucleotide.
Topics: Alcohol Oxidoreductases; Hydrogen-Ion Concentration; Kinetics; NAD; Nicotinamide Mononucleotide; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1977 |
Detection by radioimmunoassay of nicotinamide nucleotide analogues in tissues of rabbits injected with nicotine and cotinine.
Topics: Animals; Antibody Specificity; Cotinine; Haptens; NAD; NADP; Nicotinamide Mononucleotide; Nicotine; Pyrrolidinones; Rabbits; Radioimmunoassay | 1977 |
Characterization of a long-wavelength feature in the absorption and circular dichroism spectra of beta-nicotinamide adenine dinucleotide. Evidence for a charge transfer transition.
Topics: Circular Dichroism; Molecular Conformation; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Temperature | 1978 |
The metabolism of [carboxyl-14C]anthranilic acid. I. The incorporation of radioactivity into NAD+ and NADP+.
Topics: Animals; Hydroxylation; Liver; Male; Microsomes, Liver; Models, Biological; NAD; NADP; Nicotinamide Mononucleotide; ortho-Aminobenzoates; Rats | 1978 |
[Characteristics of NAD glycohydrolase of rat thymocytes].
Topics: Animals; Chemical Fractionation; Hydrolases; Lymphocytes; NAD; NADP; Nicotinamide Mononucleotide; Rats; Spleen; Thymus Gland | 1978 |
Metabolism of niacin and niacinamide in perfused rat intestine.
Topics: Animals; Biological Transport; Injections; Intestinal Absorption; Intestine, Small; Male; NAD; NAD+ Nucleosidase; NADP; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Perfusion; Rats; Ribonucleotides; Time Factors | 1979 |
Depression by NAD of x-ray-induced repair-type DNA synthesis in toluene-treated Bacillus subtilis.
Topics: Adenosine Triphosphate; Bacillus subtilis; DNA Nucleotidyltransferases; DNA Repair; DNA, Bacterial; Kinetics; NAD; Nicotinamide Mononucleotide; Radiation Effects; Time Factors; Toluene | 1975 |
Ultrastructural demonstration of NAD-pyrophosphorylase activity in mouse liver nuclei.
Topics: Adenosine Triphosphatases; Animals; Cell Nucleus; Chromatin; Ethanol; Formaldehyde; Histocytochemistry; Liver; Mice; Microscopy, Electron; NAD; Nicotinamide Mononucleotide; Nucleotidyltransferases | 1975 |
Role for deoxyribonucleic acid ligase in deoxyribonucleic acid polymerase i-dependent repair synthesis in toluene-treated escherichia coli.
Topics: DNA Nucleotidyltransferases; DNA Repair; DNA, Bacterial; Enzyme Activation; Escherichia coli; Genes; Mutation; NAD; Nicotinamide Mononucleotide; Polynucleotide Ligases; Radiation Effects; Temperature; Toluene; X-Rays | 1975 |
Pyridine nucleotide metabolism in mitotic cells.
Topics: Cell Line; Colchicine; Kinetics; Mitosis; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids | 1975 |
Role of deoxyribonucleic acid polymerases and deoxyribonucleic acid ligase in x-ray-induced repair synthesis in toluene-treated Escherichia coli K-12.
Topics: Adenosine Triphosphate; Cell Membrane Permeability; DNA Nucleotidyltransferases; DNA Repair; DNA, Bacterial; Escherichia coli; Isoenzymes; Mutation; NAD; Nicotinamide Mononucleotide; Polynucleotide Ligases; Radiation Effects; Toluene; X-Rays | 1976 |
Modification of Escherichia coli DNA ligase by cleavage with trypsin.
Topics: Escherichia coli; NAD; Nicotinamide Mononucleotide; Peptide Fragments; Polynucleotide Ligases; Trypsin | 1976 |
[Synthesis of nicotinamide adenine dinucleotide in the nuclei of pigeon erythrocytes].
Topics: Adenosine Triphosphate; Animals; Columbidae; Erythrocytes; NAD; Nicotinamide Mononucleotide | 1975 |
Repair of x-ray-induced single strand breaks in toluenized Escherichia coli cells.
Topics: Adenosine Triphosphate; Deoxyribonucleotides; DNA Repair; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; NAD; Nicotinamide Mononucleotide; Radiation Effects; Ribonucleotides; Thymidine; Toluene | 1976 |
An investigation of the nicotinamide-adenine dinucleotide-induced 'tightening' of the structure of glyceraldehyde 3-phosphate dehydrogenase.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Sugars; Adenosine Monophosphate; Adenosine Triphosphate; Glyceraldehyde-3-Phosphate Dehydrogenases; Inosine Nucleotides; Kinetics; Magnesium; NAD; Nicotinamide Mononucleotide; Protein Binding; Protein Conformation; Saccharomyces cerevisiae | 1976 |
Stimulation of the hypoxanthine and NADH-dehydrogenation by nicotinamide.
Topics: Animals; Hypoxanthines; Ketone Oxidoreductases; Liver; Male; NAD; Nicotinamide Mononucleotide; Rats; Xanthine Dehydrogenase | 1976 |
Synthesis of pyridine nucleotides by mitochondrial fractions of yeast.
Topics: Adenosine Triphosphate; Magnesium; Mitochondria; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Phosphoribosyl Pyrophosphate; Saccharomyces cerevisiae; Sonication | 1976 |
Effect of diet restriction on some key enzymes tryptophan-NAD pathway in rats.
Topics: Animals; Carboxy-Lyases; Dietary Proteins; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Liver; Male; NAD; Nicotinamide Mononucleotide; Nicotinic Acids; Nutrition Disorders; Pentosephosphates; Pentosyltransferases; Picolinic Acids; Quinolinic Acids; Rats; Tryptophan; Tryptophan Oxygenase | 1977 |
Circular dichroic properties and conformation of thionicotinamide dinucleotides.
Topics: Adenosine Monophosphate; Circular Dichroism; Molecular Conformation; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Thionucleotides | 1978 |
Formation of P1, P2-dinucleoside 5'-pyrophosphates under potentially prebiological conditions.
Topics: Adenosine; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Imidazoles; Magnesium; NAD; Nicotinamide Mononucleotide; Uracil Nucleotides; Uridine Diphosphate; Uridine Monophosphate | 1978 |
Concerning the mechanism of the enzymatic and nonenzymatic hydrolysis of nicotinamide nucleotide coenzymes.
Topics: Animals; Brain; Deuterium; Kinetics; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Neurospora crassa; Nicotinamide Mononucleotide; Swine | 1978 |
Pyridine nucleotide cycle of Salmonella typhimurium: regulation of nicotinic acid phosphoribosyltransferase and nicotinamide deamidase.
Topics: Amidohydrolases; Enzyme Repression; Mutation; NAD; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinic Acids; Pentosyltransferases; Salmonella typhimurium | 1979 |
Proton nuclear magnetic resonance study of the conformation and configuration of the cyclized pyridine nucleotide adducts.
Topics: Acetaldehyde; Magnetic Resonance Spectroscopy; Molecular Conformation; NAD; Nicotinamide Mononucleotide; Oxaloacetates; Pyrimidine Nucleotides; Pyruvates | 1979 |
Electrochemical oxidation in aqueous and nonaqueous media of dihydropyridine nucleotides NMNH, NADH, and NADPH.
Topics: Dimethyl Sulfoxide; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; NAD; NADP; Nicotinamide Mononucleotide; Oxidation-Reduction; Ribonucleotides; Water | 1975 |
Nuclear magnetic resonance studies on pyridine dinucleotides. II. Solution conformational dynamics of nicotinamide adenine dinucleotide and nicotinamide mononucleotide as viewed by proton T1 measurements.
Topics: Energy Transfer; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Conformation; NAD; Nicotinamide Mononucleotide; Protons; Ribonucleotides; Solutions; Temperature | 1975 |
Affinity chromatography of enzyme cofactors: the separation of NAD on immobilised dehydrogenase colums.
Topics: Alcohol Oxidoreductases; Chromatography, Affinity; DEAE-Cellulose; Dialysis; Evaluation Studies as Topic; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; NAD; Nicotinamide Mononucleotide; Protein Binding; Saccharomyces cerevisiae; Sepharose; Ultrafiltration | 1975 |
Circular dichroism studies of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli B, MB 1428: ternary complexes.
Topics: Adenosine Diphosphate Sugars; Binding Sites; Circular Dichroism; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Methotrexate; NAD; NADP; Nicotinamide Mononucleotide; Protein Binding; Protein Conformation; Ribose; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase | 1975 |
Convenient method for preparation and purification of nicotinamide mononucleotide analogs.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Animals; Horses; Liver; Methods; NAD; NADP; Nicotinamide Mononucleotide; Nucleotidyltransferases; Pyrophosphatases; Ribonucleotides; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine | 1975 |
NAD synthesis in human erythrocytes: study of adenylyl transferase activities in patients bearing purine enzyme disorders.
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; Erythrocytes; Humans; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Kinetics; NAD; Nicotinamide Mononucleotide; Nucleotidyltransferases; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors | 1991 |
Regulation of pyridine nucleotide coenzyme metabolism.
Topics: Animals; Dietary Proteins; Liver; Male; NAD; Niacin; Nicotinamide Mononucleotide; Organ Specificity; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Determination of NAD pyrophosphorylase activity in biological samples.
Topics: Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver; Male; NAD; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Rats; Rats, Inbred Strains; Reproducibility of Results; Sensitivity and Specificity | 1991 |
The nadI region of Salmonella typhimurium encodes a bifunctional regulatory protein.
Topics: Bacterial Proteins; Biological Transport; Chromosome Deletion; Genes, Bacterial; Genes, Dominant; Genetic Complementation Test; Mutagenesis, Insertional; Mutation; NAD; Nicotinamide Mononucleotide; Phenotype; Promoter Regions, Genetic; Salmonella typhimurium; Transcription Factors; Transcription, Genetic | 1991 |
Activity of the nicotinamide mononucleotide transport system is regulated in Salmonella typhimurium.
Topics: Bacterial Proteins; Biological Transport; Gene Expression Regulation, Bacterial; Genes, Bacterial; Membrane Proteins; Mutation; NAD; Nicotinamide Mononucleotide; Salmonella typhimurium; Transcription Factors | 1991 |
Purification and characterization of a pyridine nucleotide glycohydrolase from rabbit spleen.
Topics: Animals; Catalysis; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Chromatography, Gel; Glycosides; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; N-Glycosyl Hydrolases; NAD; Nicotinamide Mononucleotide; Rabbits; Solubility; Spleen; Substrate Specificity | 1989 |
Kinetic analysis of the transglycosidation reaction catalyzed by rabbit spleen pyridine nucleotide glycohydrolase.
Topics: Animals; Catalysis; Detergents; Glycosides; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; N-Glycosyl Hydrolases; NAD; NADP; Niacin; Nicotinamide Mononucleotide; Octoxynol; Polyethylene Glycols; Rabbits; Spleen; Substrate Specificity | 1989 |
Superoxide is responsible for the vanadate stimulation of NAD(P)H oxidation by biological membranes.
Topics: Animals; Antimycin A; Intracellular Membranes; Male; Microsomes, Liver; NAD; NADP; Nicotinamide Mononucleotide; Oxidation-Reduction; Paraquat; Rats; Rotenone; Superoxides; Vanadates | 1988 |
Activity of NMN+, nicotinamide ribose and analogs in alcohol oxidation promoted by horse-liver alcohol dehydrogenase. Improvement of this activity and structural requirements of the pyridine nucleotide part of the NAD+ coenzyme.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcohols; Animals; Coenzymes; Horses; Kinetics; Liver; NAD; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Pyridinium Compounds; Structure-Activity Relationship | 1986 |
Defining the metabolic and growth responses of porcine haemophili to exogenous pyridine nucleotides and precursors.
Topics: Animals; Glucose; Haemophilus; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Swine | 1986 |
Pyridine nucleotide metabolism by extracts derived from Haemophilus parasuis and H. pleuropneumoniae.
Topics: Adenosine Triphosphate; Haemophilus; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Species Specificity | 1986 |
A radioenzymatic assay for quinolinic acid.
Topics: Adult; Humans; Male; NAD; Nicotinamide Mononucleotide; Pentosyltransferases; Pyridines; Quinolinic Acid; Quinolinic Acids; Tritium | 1986 |
Metabolism of nicotinamide mononucleotide in beef liver.
Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Cattle; Liver; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Nicotinamide Mononucleotide; Nucleotidases; Purine-Nucleoside Phosphorylase | 1987 |
Regulation of NAD metabolism in Salmonella typhimurium: genetic analysis and cloning of the nadR repressor locus.
Topics: Biological Transport; Chromosome Deletion; Cloning, Molecular; DNA Transposable Elements; Mutation; NAD; Nicotinamide Mononucleotide; Operator Regions, Genetic; Operon; Oxygen; Repressor Proteins; Salmonella typhimurium; Transcription Factors; Transcription, Genetic | 1987 |
Femtosecond charge separation in organized assemblies: free-radical reactions with pyridine nucleotides in micelles.
Topics: Adenosine Monophosphate; Electron Transport; Free Radicals; Kinetics; Micelles; Models, Biological; NAD; Nicotinamide Mononucleotide; Phenothiazines; Sodium Dodecyl Sulfate; Time Factors | 1988 |
Genetic characterization of pyridine nucleotide uptake mutants of Salmonella typhimurium.
Topics: Biological Transport; Chromosome Mapping; Genetic Linkage; Genotype; Mutation; NAD; Niacin; Nicotinamide Mononucleotide; Salmonella typhimurium | 1985 |
Purine and pyridine nucleotide production in human erythrocytes.
Topics: Adenine Nucleotides; Adenine Phosphoribosyltransferase; Adenosine Triphosphate; Erythrocytes; Humans; In Vitro Techniques; Kinetics; NAD; Nicotinamide Mononucleotide; Pentosyltransferases | 1986 |
Allosteric effect of fructose 1,6-bisphosphate on the conformation of NAD+ as bound to L-lactate dehydrogenase from Thermus caldophilus GK24.
Topics: Adenosine; Allosteric Regulation; Allosteric Site; Fructosediphosphates; Hexosediphosphates; Kinetics; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Molecular Conformation; NAD; Nicotinamide Mononucleotide; Protein Binding; Thermus | 1985 |
Purification and properties of nicotinamide mononucleotide amidohydrolase from Azotobacter vinelandii.
Topics: Amidohydrolases; Ammonium Sulfate; Azotobacter; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Glycosides; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Nicotinamide Mononucleotide; Nucleotidyltransferases; Optical Rotatory Dispersion; Pentosyltransferases; Phosphoric Diester Hydrolases; Spectrophotometry; Streptomycin; Time Factors; Ultraviolet Rays | 1973 |
Distrbution of enzymes between nucleus and cytoplasm of single nerve cell bodies.
Topics: Adenosine Triphosphate; Animals; Cell Nucleus; Cytoplasm; Ganglia, Spinal; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Hexokinase; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Malate Dehydrogenase; Male; NAD; NADP; Neurons; Nicotinamide Mononucleotide; Nucleotidyltransferases; Phosphofructokinase-1; Phosphogluconate Dehydrogenase; Rabbits; Solubility; Surface-Active Agents | 1973 |
Biosynthesis of pyridine nucleotides in early embryos of the mouse (Mus musculus).
Topics: Animals; Azaserine; Carbon Isotopes; Chorionic Gonadotropin; Embryo Implantation; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fertilization; Humans; Male; Mice; Mitosis; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Ovum; Pregnancy; Pyridines | 1973 |
Pyridine nucleotide metabolism in Escherichia coli. II. Niacin starvation.
Topics: Carbon Isotopes; Cell Division; Chromatography, Paper; Culture Media; Dose-Response Relationship, Drug; Escherichia coli; Microscopy, Electron; Mutation; NAD; NADP; Nicotinamide Mononucleotide; Nicotinic Acids; Species Specificity; Time Factors | 1973 |
Effects of leucine and isoleucine on nicotinamide nucleotides of erythrocytes.
Topics: Adult; Blood Glucose; Carbon Dioxide; Carbon Radioisotopes; Drug Synergism; Erythrocytes; Feces; Glycolysis; Humans; Isoleucine; Lactates; Leucine; Male; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Pyridines; Ribonucleotides; Time Factors | 1973 |
Natural abundance 13C nuclear magnetic resonance spectra of nicotinamide adenine dinucleotide and related nucleotides.
Topics: Adenosine Monophosphate; Carbon Isotopes; Chemical Phenomena; Chemistry; Magnetic Resonance Spectroscopy; Molecular Conformation; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Protons; Ribose; Time Factors | 1973 |
The biosynthesis and turnover of nicotinamide adenine dinucleotide in enucleated culture cells.
Topics: Autoradiography; Azaserine; Bone Marrow; Bone Marrow Cells; Cell Fractionation; Cell Line; Cell Nucleus; Cells, Cultured; Chromatography, Paper; Microsomes; N-Glycosyl Hydrolases; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Tritium | 1974 |
Pyridine nucleotide synthesis. Purification of nicotinamide mononucleotide pyrophosphorylase from rat erythrocytes.
Topics: Adenosine Triphosphate; Ammonium Sulfate; Animals; Carbon Isotopes; Chromatography, DEAE-Cellulose; Drug Stability; Edetic Acid; Erythrocytes; Hemolysis; Hydrogen-Ion Concentration; Kinetics; Magnesium; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Nucleotidyltransferases; Pentosephosphates; Phosphoric Acids; Rats | 1972 |
Pyridinium precursors of pyridine nucleotides in perfused rat kidney and in the testis.
Topics: Adenosine Triphosphate; Amidohydrolases; Animals; Carbon Isotopes; Kidney; Male; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Nucleotidyltransferases; Perfusion; Pyridines; Pyridinium Compounds; Rats; Testis; Uric Acid | 1972 |
Discontinuous DNA replication in vitro. I. Two distinct size classes of intermediates.
Topics: Carbon Isotopes; Centrifugation, Density Gradient; Deoxyribonucleotides; DNA Replication; DNA, Bacterial; Escherichia coli; Kinetics; Ligases; NAD; Nicotinamide Mononucleotide; Polynucleotide Ligases; Polynucleotides; Thymine Nucleotides; Tritium | 1972 |
Metabolism of pyridine nucleotides and its relation to DNA synthesis in regenerating mouse liver.
Topics: Adenine Nucleotides; Animals; DNA; Female; Hepatectomy; Hydrolases; Kynurenine; Liver; Liver Regeneration; Mice; Mice, Inbred Strains; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotidyltransferases; ortho-Aminobenzoates; Pentosyltransferases; Transaminases; Tryptophan | 1972 |
DNA synthesis in nucleotide-permeable Escherichia coli cells. VII. Conversion of phi chi-174 DNA to its replicative form.
Topics: Centrifugation, Density Gradient; Coliphages; DNA Replication; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Kinetics; Ligases; NAD; Nicotinamide Mononucleotide; Nucleosides; Phosphorus Isotopes; Sulfur Isotopes; Tritium | 1973 |
Deoxyribonucleic acid ligase. A steady state kinetic analysis of the reaction catalyzed by the enzyme from Escherichia coli.
Topics: Adenosine Monophosphate; Catalysis; Cations, Monovalent; Deoxyribonucleotides; DNA; Escherichia coli; Exonucleases; Kinetics; NAD; Nicotinamide Mononucleotide; Phosphorus Radioisotopes; Polynucleotide Ligases; Polynucleotides; Quaternary Ammonium Compounds; Regression Analysis; Structure-Activity Relationship; Tritium | 1973 |
Biosynthesis of NAD in Haemophilus haemoglobinophilus.
Topics: Carbon Radioisotopes; Chromatography, Paper; Electrophoresis, Paper; Haemophilus; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Pentosyltransferases; Pyridines; Ribose | 1973 |
Biliary excretion of nicotinamide riboside. A possible role in the regulation of hepatic pyridine nucleotide dynamics.
Topics: Animals; Bile; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Female; Fluorometry; Freeze Drying; Liver; Methylation; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Rats; Ribonucleosides; Time Factors | 1973 |
Interaction of nucleotides with liver uridine diphosphate-glucose-4'-epimerase.
Topics: Adenine Nucleotides; Ammonium Sulfate; Animals; Apoproteins; Carbohydrate Epimerases; Cattle; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Glucose; Liver; Macromolecular Substances; Molecular Weight; NAD; Nicotinamide Mononucleotide; Nucleotides; Picolinic Acids; Protein Binding; Protein Conformation; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Uridine Diphosphate Sugars | 1974 |
The equilibria and reaction rates of nicotinamide-adenine dinucleotide and its related compounds with cyanide ion in the presence of polyelectrolytes.
Topics: Allyl Compounds; Chemical Phenomena; Chemistry; Cyanides; DNA; Kinetics; NAD; Niacinamide; Nicotinamide Mononucleotide; Polymers; Polynucleotides; Polyvinyls; Pyridinium Compounds; Quaternary Ammonium Compounds; Ribonucleotides; Surface-Active Agents; Thermodynamics | 1974 |
A new method of assay for polynucleotide ligase.
Topics: Adenine Nucleotides; Chromatography, DEAE-Cellulose; Deoxyribonucleases; Deoxyribonucleotides; DNA Nucleotidyltransferases; Escherichia coli; Evaluation Studies as Topic; Kinetics; Methods; Mutation; NAD; Nicotinamide Mononucleotide; Oligonucleotides; Pancreas; Polynucleotide Ligases; Polynucleotides; Spectrophotometry, Ultraviolet; Templates, Genetic; Thymine Nucleotides; Time Factors; Tritium | 1974 |
A Raman and infrared spectroscopic study of the 3-carbonyl group of pyridine nucleotide coenzymes and related model compounds.
Topics: Acetates; Aldehydes; Chemical Phenomena; Chemistry; Coenzymes; Deuterium; Dioxins; Drug Stability; Models, Chemical; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Oxidation-Reduction; Pyridines; Ribonucleotides; Spectrophotometry, Infrared; Spectrum Analysis | 1974 |
Simple methods of preparing nicotinamide mononucleotide.
Topics: Animals; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Evaluation Studies as Topic; Horses; L-Lactate Dehydrogenase; Methods; NAD; Niacinamide; Nicotinamide Mononucleotide; Plants; Pyrophosphatases; Ribonucleotides; Spectrophotometry, Ultraviolet | 1974 |
Continuous synthesis of NAD in a nuclear column.
Topics: Adenosine Triphosphate; Animals; Cell Nucleus; Drug Stability; Evaluation Studies as Topic; Kinetics; Liver; Methods; NAD; Nicotinamide Mononucleotide; Nucleotidyltransferases; Pressure; Rats; Solubility; Time Factors | 1973 |
Purification and properties of quinolinate phosphoribosyltransferase from the "Shiitake" mushroom (Lentinus edodes).
Topics: Basidiomycota; Carbon Radioisotopes; Cations, Divalent; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Fractional Precipitation; Hydrogen-Ion Concentration; Kinetics; Metals; Microsomes; Mitochondria; Molecular Weight; NAD; Nicotinamide Mononucleotide; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Quinolinic Acids; Spectrophotometry, Ultraviolet; Subcellular Fractions | 1974 |
Characteristics of quinolinate phosphoribosyltransferase from the "Shiitake" mushroom (Lentinus edodes).
Topics: Adenosine Triphosphate; Aluminum; Anti-Bacterial Agents; Basidiomycota; Chlorides; Iron; Isomerism; Lactones; Metals; NAD; Nickel; Nicotinamide Mononucleotide; Nitrates; Nucleotides; Organophosphorus Compounds; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Quinolinic Acids; Structure-Activity Relationship; Sulfhydryl Reagents; Temperature; Zinc | 1974 |
Nucleotide-dependent inactivation of RNA polymerase from Bacillus brevis.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bacillus; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Cytosine Nucleotides; DNA-Directed RNA Polymerases; Electrophoresis, Polyacrylamide Gel; Glycerol; Guanosine Triphosphate; Molecular Weight; NAD; NADP; Nicotinamide Mononucleotide; Peptides; Phosphorus Isotopes; Ribonucleotides; Uracil Nucleotides | 1972 |
Bull semen nicotinamide adenine dinucleotide nucleosidase. V. Kinetic studies.
Topics: Adenine Nucleotides; Aldehydes; Animals; Binding, Competitive; Catalysis; Cattle; Drug Stability; Feedback; Hydrolysis; Hypoxanthines; Kinetics; Male; Mathematics; N-Glycosyl Hydrolases; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Nucleotides; Pyridines; Ribonucleotides; Semen; Structure-Activity Relationship; Sulfides | 1973 |
Vanadate and molybdate stimulate the oxidation of NADH by superoxide radical.
Topics: Free Radicals; Molybdenum; NAD; Nicotinamide Mononucleotide; Osmolar Concentration; Oxidation-Reduction; Superoxide Dismutase; Superoxides; Vanadates; Vanadium | 1984 |
Crystallographic investigations of nicotinamide adenine dinucleotide binding to horse liver alcohol dehydrogenase.
Topics: Adenine; Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallography; Diphosphates; Liver; Molecular Conformation; NAD; Niacinamide; Nicotinamide Mononucleotide; Protein Conformation; Ribose | 1984 |
NAD metabolism in Salmonella typhimurium: isolation of pyridine analogue supersensitive (pas) and pas suppressor mutants.
Topics: 6-Aminonicotinamide; Chromosome Mapping; Chromosomes, Bacterial; DNA Transposable Elements; Genes, Bacterial; Genes, Regulator; Mutation; NAD; Niacin; Nicotinamide Mononucleotide; Pentosyltransferases; Phenotype; Salmonella typhimurium; Suppression, Genetic; Transduction, Genetic | 1984 |
Preparation and purification of nicotinamide mononucleotide analogs.
Topics: Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Crotalid Venoms; Kinetics; NAD; NADP; Nicotinamide Mononucleotide; Pyrophosphatases | 1980 |
Pyridine nucleotide cycle of Salmonella typhimurium: in vitro demonstration of nicotinamide adenine dinucleotide glycohydrolase, nicotinamide mononucleotide glycohydrolase, and nicotinamide adenine dinucleotide pyrophosphatase activities.
Topics: Enzyme Repression; Feedback; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Nicotinamide Mononucleotide; Periodicity; Pyrophosphatases; Salmonella typhimurium | 1981 |
Nucleoside salvage pathway for NAD biosynthesis in Salmonella typhimurium.
Topics: NAD; Niacinamide; Nicotinamide Mononucleotide; Phosphorylation; Pyridinium Compounds; Salmonella typhimurium | 1982 |
Reactivation of NAD(H) biosynthetic pathway by exogenous NAD+ in Nil cells severely depleted of NAD(H).
Topics: Animals; Cell Division; Cell Line; Cricetinae; DNA; Fibroblasts; Glucose; Interphase; Lactates; Lactic Acid; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Protein Biosynthesis | 1983 |
Isoniazid perturbation of the pyridine nucleotide cycle of Escherichia coli.
Topics: Escherichia coli; Isoniazid; Mutation; NAD; NADP; Niacin; Niacinamide; Nicotinamide Mononucleotide | 1982 |
The role of membrane-bound 5'-nucleotidase in the transport and utilization of nicotinic acid ribonucleotide.
Topics: 5'-Nucleotidase; Animals; Biological Transport; Liver; Male; NAD; Nicotinamide Mononucleotide; Nicotinic Acids; Nucleotidases; Rats; Ribonucleosides; Tissue Distribution | 1980 |
Apparent pyridine nucleotide synthesis in mitochondria: an artifact of NMN and NAD glycohydrolase activity?
Topics: Animals; Female; In Vitro Techniques; Microsomes, Liver; Mitochondria, Liver; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Rats | 1981 |
Pyridine nucleotide metabolism in the erythrocyte of South African blacks with primary hepatoma.
Topics: Black People; Carcinoma, Hepatocellular; Erythrocytes; Humans; Liver Neoplasms; Models, Biological; NAD; NADP; Niacin; Niacinamide; Nicotinamide Mononucleotide; South Africa | 1982 |
Preliminary evidence for a pyridine nucleotide cycle in Bordetella pertussis.
Topics: Bordetella pertussis; NAD; Niacin; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide | 1984 |
In vivo studies of pyridine nucleotide metabolism in Escherichia coli and Saccharomyces cerevisiae by carbon-13 NMR spectroscopy.
Topics: Escherichia coli; Magnetic Resonance Spectroscopy; NAD; NADP; Nicotinamide Mononucleotide; Nicotinic Acids; Oxidation-Reduction; Saccharomyces cerevisiae | 1984 |
Pyridine nucleotide cycle of Salmonella typhimurium: in vivo recycling of nicotinamide adenine dinucleotide.
Topics: Amidohydrolases; Mutation; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinic Acids; Salmonella typhimurium | 1980 |
The cytochrome complement of Haemophilus parasuis.
Topics: Ascorbic Acid; Carbon Monoxide; Culture Media; Cytochromes; Haemophilus; Ligands; NAD; NADP; Nicotinamide Mononucleotide; Osmotic Pressure; Oxygen Consumption; Spectrophotometry; Succinates; Succinic Acid; Tetramethylphenylenediamine | 1984 |
Degradation of NAD by synaptosomes and its inhibition by nicotinamide mononucleotide: implications for the role of NAD as a synaptic modulator.
Topics: Adenosine; Animals; Brain; Evoked Potentials; Guinea Pigs; NAD; Nicotinamide Mononucleotide; Rats; Synapses; Synaptic Membranes; Synaptosomes | 1984 |
[Bioavailability of pyridine compounds in seeds of Ricinus communis L. at various stages of germination].
Topics: Biological Availability; Chromatography, High Pressure Liquid; NAD; NADP; Nicotinamide Mononucleotide; Plants, Toxic; Pyridines; Ricinus; Seeds | 1984 |
Pyridine nucleotide synthesis in human blood--effect of leucine, alpha-ketoisocaproic acid and ketone bodies.
Topics: Adenine Nucleotides; Humans; Keto Acids; Ketone Bodies; Leucine; NAD; NADP; Niacin; Nicotinamide Mononucleotide | 1983 |
Impaired incision of ultraviolet-irradiated deoxyribonucleic acid in uvrC mutants of Escherichia coli.
Topics: DNA Repair; DNA, Bacterial; Escherichia coli; Genes; NAD; Nicotinamide Mononucleotide; Toluene; Ultraviolet Rays | 1980 |
The pyridine nucleotide cycle. Studies in Escherichia coli and the human cell line D98/AH2.
Topics: Escherichia coli; HeLa Cells; Humans; Kinetics; NAD; Nicotinamide Mononucleotide; Species Specificity | 1981 |
Synthesis of [ribose (NMN)-14C]nicotinamide adenine dinucleotide from D-[14C]glucose.
Topics: Carbon Radioisotopes; Glucose; NAD; Nicotinamide Mononucleotide; Radioisotope Dilution Technique | 1981 |
A reflectance spectrophotometer-surface fluorometer suitable for monitoring changes in hemoprotein spectra and fluorescence of flavins and nicotinamide nucleotides in intact tissues.
Topics: Animals; Flavins; Fluorometry; Hemeproteins; Mitochondria, Heart; NAD; NADP; Nicotinamide Mononucleotide; Oxygen Consumption; Rats; Spectrometry, Fluorescence | 1982 |
The hydrolysis of nicotinamide adenine nucleotide by brush border membranes of rat intestine.
Topics: Animals; Cell Fractionation; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Intestinal Mucosa; Microvilli; NAD; Nicotinamide Mononucleotide; Rats; Rats, Inbred Strains; Time Factors | 1982 |
NAD(P) adducts as protective agents against glutamate dehydrogenase inactivation by pyridoxal 5'-phosphate: a tool for the study of oxidized coenzyme activated state in enzymatic evolutive and abortive complexes.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Glutamate Dehydrogenase; Ketoglutaric Acids; Male; NAD; NADP; Nicotinamide Mononucleotide; Oxaloacetates; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Structure-Activity Relationship; Time Factors | 1982 |
Single-electron transfer from NADH analogues to singlet oxygen.
Topics: Chemical Phenomena; Chemistry; Electron Transport; Lasers; Mathematics; NAD; NADP; Nicotinamide Mononucleotide; Oxygen; Photolysis | 1981 |
Formation of nicotinamide ribose diphosphate ribose, a new metabolite of the NAD pathway, by Aspergillus niger.
Topics: Aspergillus niger; Methods; NAD; Nicotinamide Mononucleotide; Spectrophotometry, Ultraviolet | 1980 |
Isolation of NAD cycle mutants defective in nicotinamide mononucleotide deamidase in Salmonella typhimurium.
Topics: Amidohydrolases; Chromosome Mapping; DNA Ligases; Genetic Linkage; Hot Temperature; Mutagenesis, Insertional; Mutation; NAD; Nicotinamide Mononucleotide; Phenotype; Protein Denaturation; Salmonella typhimurium; Subcellular Fractions | 1995 |
Pyridine dinucleotide biosynthesis in archaebacteria: presence of NMN adenylyltransferase in Sulfolobus solfataricus.
Topics: Adenosine Triphosphate; Hot Temperature; Isoelectric Point; Kinetics; Molecular Weight; NAD; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Subcellular Fractions; Sulfolobus | 1994 |
Cloning, nucleotide sequence, and regulation of the Bacillus subtilis nadB gene and a nifS-like gene, both of which are essential for NAD biosynthesis.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA, Bacterial; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Kinetics; Molecular Sequence Data; Mutation; NAD; Nicotinamide Mononucleotide; Nitrogen Fixation; Restriction Mapping; Sequence Homology, Amino Acid | 1993 |
Nicotinamide ribose 5'-O-[S-(3-bromo-2-oxopropyl)]thiophosphate: a new affinity label for NMN sites in enzymes.
Topics: Adenosine Diphosphate; Affinity Labels; Allosteric Regulation; Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Guanosine Triphosphate; Kinetics; Liver; NAD; NADP; Nicotinamide Mononucleotide; Organothiophosphates; Spectrophotometry, Ultraviolet | 1993 |
Phosphoribosyl diphosphate synthetase-independent NAD de novo synthesis in Escherichia coli: a new phenotype of phosphate regulon mutants.
Topics: Escherichia coli; Mutation; NAD; Nicotinamide Mononucleotide; Phenotype; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase | 1996 |
Rat liver mitochondria can synthesize nicotinamide adenine dinucleotide from nicotinamide mononucleotide and ATP via a putative matrix nicotinamide mononucleotide adenylyltransferase.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Diphosphates; Hydrogen-Ion Concentration; Male; Mitochondria, Liver; NAD; NADP; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Rats; Substrate Specificity | 1996 |
Fluorescence of reduced nicotinamides using one- and two-photon excitation.
Topics: Absorptiometry, Photon; Anisotropy; Fluorescence; Fluorescent Dyes; NAD; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Spectrometry, Fluorescence | 1996 |
The role and importance of different fragments of NAD+ in refolding of Clostridium symbiosum glutamate dehydrogenase.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Clostridium; Glutamate Dehydrogenase; Guanosine Triphosphate; Kinetics; NAD; Nicotinamide Mononucleotide; Protein Denaturation; Protein Folding; Urea | 1997 |
Affinity labels for NAD(P)-specific sites.
Topics: Adenine Nucleotides; Affinity Labels; Animals; Cattle; Glutamate Dehydrogenase; Isocitrate Dehydrogenase; Liver; Myocardium; NAD; NADP; Nicotinamide Mononucleotide; Organothiophosphates; Salmonella typhimurium; Swine | 1997 |
Determining NAD synthesis in erythrocytes.
Topics: Adenine Nucleotides; Amide Synthases; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Ligases; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nicotinamide-Nucleotide Adenylyltransferase; Nucleotidyltransferases; Pentosyltransferases | 1997 |
Detection and identification of NAD-catabolizing activities in rat tissue homogenates.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Detergents; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Kidney Cortex; Male; Molecular Weight; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Pyrophosphatases; Rats; Rats, Wistar; Spleen; Zinc | 1997 |
The reaction mechanism for CD38. A single intermediate is responsible for cyclization, hydrolysis, and base-exchange chemistries.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Binding, Competitive; Catalysis; Cyclic ADP-Ribose; Fluorescence Polarization; Guanosine Diphosphate Sugars; Humans; Hydrolysis; Kinetics; Membrane Glycoproteins; Methanol; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Spectrometry, Fluorescence; Substrate Specificity | 1998 |
Change of nucleotide specificity and enhancement of catalytic efficiency in single point mutants of Vibrio harveyi aldehyde dehydrogenase.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Aldehyde Dehydrogenase; Amino Acid Sequence; Catalysis; Enzyme Activation; Enzyme Inhibitors; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Nicotinamide Mononucleotide; Point Mutation; Substrate Specificity; Vibrio | 1999 |
NADP and NAD utilization in Haemophilus influenzae.
Topics: Adenosine; Bacterial Outer Membrane Proteins; Cell Division; Enzyme Inhibitors; Esterases; Haemophilus influenzae; Lipoproteins; Mutation; NAD; NADP; Nicotinamide Mononucleotide; Nucleotidases | 2000 |
On the irreversible destruction of reduced nicotinamide nucleotides by hypohalous acids.
Topics: Bromates; Chlorates; Hydrogen-Ion Concentration; Iodine Compounds; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; NAD; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Oxygen; Pyridines; Time Factors | 2000 |
RNA-Catalyzed CoA, NAD, and FAD synthesis from phosphopantetheine, NMN, and FMN.
Topics: Coenzyme A; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Gene Library; NAD; Nicotinamide Mononucleotide; Pantetheine; RNA; Sequence Analysis, RNA | 2000 |
NadN and e (P4) are essential for utilization of NAD and nicotinamide mononucleotide but not nicotinamide riboside in Haemophilus influenzae.
Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; Biological Transport; Esterases; Haemophilus influenzae; Lipoproteins; Models, Biological; Multienzyme Complexes; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotidases; Pyridinium Compounds; Pyrophosphatases | 2001 |
RNA aptamers that bind flavin and nicotinamide redox cofactors.
Topics: Base Sequence; Binding Sites; Evolution, Molecular; Guanosine; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Riboflavin; RNA; Sequence Analysis, RNA; Uridine | 1995 |
A novel preparation of nicotinamide mononucleotide.
Topics: Catalysis; Hydrolysis; NAD; Nicotinamide Mononucleotide; Pyrophosphatases; Zirconium | 1994 |
Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities.
Topics: Adenosine Triphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Antigens, CD; Antigens, Differentiation; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Dimerization; Disulfides; GPI-Linked Proteins; Humans; Ligands; Membrane Glycoproteins; Models, Chemical; Models, Molecular; Molecular Sequence Data; NAD; NAD+ Nucleosidase; NADP; Niacinamide; Nicotinamide Mononucleotide; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Sequence Alignment; Substrate Specificity | 2002 |
Substrate specificity of mammalian pyridine nucleotide transglycosidases.
Topics: Animals; Cattle; Glycoside Hydrolases; Guinea Pigs; Hydrolysis; Kinetics; Liver; Multienzyme Complexes; N-Glycosyl Hydrolases; NAD; NADP; Niacin; Nicotinamide Mononucleotide; Rabbits; Spectrophotometry; Spleen; Substrate Specificity; Swine; Transferases | 2002 |
Synthesis of pyridine nucleotide analogs consisting of nicotinoylamino acids by means of transglycosidation reactions catalyzed by mammalian pyridine nucleotide transglycosidases.
Topics: Animals; Catalysis; Glycoside Hydrolases; Guinea Pigs; Hydrolysis; Magnetic Resonance Spectroscopy; Multienzyme Complexes; N-Glycosyl Hydrolases; NAD; NADP; Nicotinamide Mononucleotide; Rabbits; Spleen; Transferases | 2002 |
Crystal structure and site-directed mutagenesis of enzymatic components from Clostridium perfringens iota-toxin.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Animals; Bacterial Toxins; Catalytic Domain; Clostridium perfringens; Crystallography, X-Ray; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; NAD; Nicotinamide Mononucleotide; Protein Conformation; Sequence Alignment | 2003 |
Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Molecular Sequence Data; NAD; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid | 2003 |
Porin OmpP2 of Haemophilus influenzae shows specificity for nicotinamide-derived nucleotide substrates.
Topics: Bacterial Outer Membrane Proteins; Binding Sites; Biological Transport; Haemophilus influenzae; Mutation; NAD; Nicotinamide Mononucleotide; Protein Binding; Substrate Specificity | 2003 |
Biosynthesis of diphosphopyridine nucleotide. III. Nicotinic acid mononucleotide pyrophos-phorylase.
Topics: NAD; Niacin; Nicotinamide Mononucleotide; Nicotinic Acids; Nucleosides; Nucleotides; Phosphorylases | 1961 |
STUDIES ON THE BIOSYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE. I. ENZYMIC SYNTHESIS OF NIACIN RIBONUCLEOTIDES FROM 3-HYDROXYANTHRANILIC ACID IN MAMMALIAN TISSUES.
Topics: 3-Hydroxyanthranilic Acid; Animals; Cats; Chromatography; Electrophoresis; Liver; NAD; Niacin; Nicotinamide Mononucleotide; Nucleotides; ortho-Aminobenzoates; Rats; Research | 1963 |
THE ENZYMATIC CONVERSION OF QUINOLINATE TO NICOTINIC ACID MONONUCLEOTIDE IN MAMMALIAN LIVER.
Topics: Aniline Compounds; Animals; Carbon Isotopes; Cattle; Chromatography; Glycerol; Lactobacillus; Liver; Liver Extracts; Magnesium; Manganese; Metabolism; NAD; Niacin; Nicotinamide Mononucleotide; Nicotinic Acids; Pyridines; Quinolinic Acid; Research | 1964 |
NAD+ specificity of bacterial DNA ligase revealed.
Topics: Bacteria; DNA Ligases; DNA, Bacterial; Molecular Structure; NAD; Nicotinamide Mononucleotide; Protein Structure, Tertiary | 2004 |
Structural rearrangement accompanying NAD+ synthesis within a bacterial DNA ligase crystal.
Topics: Cloning, Molecular; Crystallization; Crystallography, X-Ray; DNA Ligases; Enterococcus faecalis; Models, Molecular; NAD; Nicotinamide Mononucleotide; Protein Structure, Tertiary | 2004 |
NAD deamidation "a new reaction" by an enzyme from Aspergillus terreus DSM 826.
Topics: Acetamides; Acrylic Resins; Asparagine; Aspergillus; Chromatography, Liquid; Deamination; Enzyme Inhibitors; Enzyme Stability; Freezing; Glutamine; Hydrogen-Ion Concentration; Kinetics; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Substrate Specificity; Temperature | 2005 |
Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin.
Topics: Animals; Catalase; Cell-Free System; Humans; Hydrogen Peroxide; Kynuramine; Melatonin; NAD; Nicotinamide Mononucleotide; Oxyhemoglobins; PC12 Cells; Rats; Superoxide Dismutase | 2005 |
NAD-, NMN-, and NADP-dependent modification of dinitrogenase reductases from Rhodospirillum rubrum and Azotobacter vinelandii.
Topics: Adenosine Diphosphate Ribose; Azotobacter vinelandii; Dinitrogenase Reductase; NAD; NADP; Nicotinamide Mononucleotide; Rhodospirillum rubrum; Ribonucleotides | 2005 |
The simultaneous measurement of nicotinamide adenine dinucleotide and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Chromatography, Liquid; Erythrocytes; HL-60 Cells; Humans; Mice; Mice, Inbred BALB C; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2006 |
Comparative genomics of NAD biosynthesis in cyanobacteria.
Topics: Amide Synthases; Cyanobacteria; Escherichia coli; Gene Transfer, Horizontal; Genome, Bacterial; Glutamine; Models, Biological; Multigene Family; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nucleotidyltransferases; Pentosyltransferases; Synteny | 2006 |
Arabidopsis thaliana nicotinate/nicotinamide mononucleotide adenyltransferase (AtNMNAT) is required for pollen tube growth.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Flowers; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Complementation Test; Molecular Sequence Data; Molecular Structure; Mutation; NAD; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Pollen Tube; Recombinant Fusion Proteins | 2007 |
Nicotinamidase participates in the salvage pathway of NAD biosynthesis in Arabidopsis.
Topics: Arabidopsis; Gene Expression; Metabolic Networks and Pathways; NAD; NADP; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinic Acids; Plant Roots | 2007 |
Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme.
Topics: Adipose Tissue, Brown; Animals; Cell Differentiation; Cell Line; Female; Glucose Intolerance; Immunoprecipitation; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Kidney; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Signal Transduction | 2007 |
Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice.
Topics: Aging; Animals; Female; Glucose; Glucose Tolerance Test; In Vitro Techniques; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ion Channels; Islets of Langerhans; Male; Mice; Mice, Transgenic; Mitochondrial Proteins; NAD; Nicotinamide Mononucleotide; Sirtuin 1; Sirtuins; Uncoupling Protein 2 | 2008 |
Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase.
Topics: Acrylamides; Adenosine Triphosphate; Cytokines; Enzyme Inhibitors; Enzyme Stability; Humans; Hydrolysis; In Vitro Techniques; Kinetics; Models, Biological; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Phosphorylation; Piperidines; Recombinant Proteins; Thermodynamics | 2008 |
Covalent and noncovalent intermediates of an NAD utilizing enzyme, human CD38.
Topics: ADP-ribosyl Cyclase 1; Catalysis; Crystallography, X-Ray; Glycosides; Humans; Models, Molecular; Molecular Structure; NAD; Nicotinamide Mononucleotide; Protein Binding | 2008 |
Theoretical studies of the quinolinic acid to nicotinic acid mononucleotide transformation.
Topics: Carbon; Carbon Dioxide; Chemistry, Organic; Computational Biology; Decarboxylation; Models, Chemical; Models, Theoretical; NAD; Nicotinamide Mononucleotide; Orotidine-5'-Phosphate Decarboxylase; Quinolinic Acid; Software; Solvents; Thermodynamics | 2008 |
Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis.
Topics: Bacillus anthracis; Bacterial Proteins; Computer Simulation; Francisella tularensis; Genome, Bacterial; Kinetics; Models, Molecular; NAD; Nicotinamide Mononucleotide; Protein Structure, Quaternary; Protein Structure, Tertiary | 2009 |
Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo.
Topics: Acetophenones; Acrylamides; Animals; Cell Survival; Chromatography, High Pressure Liquid; Cytokines; Enzyme Inhibitors; Formates; HeLa Cells; Humans; Male; Mice; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Organ Specificity; Piperidines; U937 Cells | 2009 |
Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.
Topics: 5'-Nucleotidase; Gene Knockout Techniques; Glucose; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Ribonucleosides; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Vitamins | 2009 |
Visualization and quantification of NAD(H) in brain sections by a novel histo-enzymatic nitrotetrazolium blue staining technique.
Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Enzyme Inhibitors; Formazans; Hippocampus; Male; NAD; NAD+ Nucleosidase; Nicotinamide Mononucleotide; Nitroblue Tetrazolium; Perchlorates; Rats; Rats, Inbred F344; Spectrometry, Fluorescence; Staining and Labeling; Time Factors | 2010 |
Mitochondria-localized NAD biosynthesis by nicotinamide mononucleotide adenylyltransferase in Jerusalem artichoke (Helianthus tuberosus L.) heterotrophic tissues.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Adenosine Triphosphate; Cell Fractionation; Chromatography, High Pressure Liquid; Diphosphates; Helianthus; Heterotrophic Processes; Hydrogen-Ion Concentration; Kinetics; Mitochondria; NAD; NADP; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Oxygen; Plant Tubers; Substrate Specificity; Temperature | 2011 |
Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Cloning, Molecular; Enzyme Activation; Escherichia coli; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Pentosyltransferases; Plasmids; Recombinant Proteins; Structural Homology, Protein; Sugar Phosphates | 2012 |
Wld(S) reduces paraquat-induced cytotoxicity via SIRT1 in non-neuronal cells by attenuating the depletion of NAD.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Herbicides; Hydrogen Peroxide; Injections, Intraperitoneal; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Mitochondria, Liver; Mutation; NAD; Nerve Tissue Proteins; Nicotinamide Mononucleotide; Oxidants; Paraquat; Reactive Oxygen Species; Sirtuin 1 | 2011 |
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Crystallization; Gene Expression Regulation, Bacterial; Haemophilus influenzae; Humans; Models, Molecular; Molecular Sequence Data; NAD; Nicotinamide Mononucleotide; Nucleotidases; Protein Conformation; Pyrophosphatases; Zinc | 2012 |
Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice.
Topics: Aging; Animals; Circadian Rhythm; Cytokines; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation; Glucose; Hypoglycemic Agents; Insulin; Lipid Metabolism; Mice; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Oxidative Stress; Sirtuin 1 | 2011 |
Identification of mitochondrial electron transport chain-mediated NADH radical formation by EPR spin-trapping techniques.
Topics: Animals; Biocatalysis; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Electron Transport Chain Complex Proteins; Electron Transport Complex I; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Kinetics; Male; Mitochondria, Heart; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spin Trapping; Submitochondrial Particles; Uncoupling Agents | 2011 |
Comparison of the formation of nicotinic acid conjugates in leaves of different plant species.
Topics: Alkaloids; Carbon Radioisotopes; Embryophyta; Glucosides; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Plant Leaves; Species Specificity; Time Factors | 2012 |
NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity.
Topics: Acrylamides; Animals; Bone and Bones; Cell Differentiation; Coculture Techniques; Cytokines; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mice; Mice, SCID; Multiple Myeloma; NAD; Neoplasm Proteins; NF-kappa B; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Osteoclasts; Osteolysis; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rabbits; Sirtuin 1; Tumor Cells, Cultured; Up-Regulation | 2013 |
Investigation of NADH binding, hydride transfer, and NAD(+) dissociation during NADH oxidation by mitochondrial complex I using modified nicotinamide nucleotides.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Binding, Competitive; Cattle; Coenzymes; Electron Transport Complex I; Flavins; Hydrogen; Kinetics; Mitochondria, Heart; Models, Molecular; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction; Protein Binding | 2013 |
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells.
Topics: 5'-Nucleotidase; Acrylamides; ADP-ribosyl Cyclase 1; Cell Death; Cell Line, Tumor; Cytokines; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; GPI-Linked Proteins; Humans; Membrane Glycoproteins; NAD; Neoplasm Proteins; Neoplasms; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines | 2013 |
Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.
Topics: Acetates; Cell Hypoxia; Cell Line, Tumor; Cells; Citric Acid; Citric Acid Cycle; Fatty Acids; Glutamine; Humans; Ketoglutaric Acids; Lactic Acid; Models, Biological; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase | 2013 |
Discovery of a novel nicotinamide phosphoribosyl transferase (NAMPT) inhibitor via in silico screening.
Topics: Animals; Antineoplastic Agents; Apoptosis; Computer Simulation; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia; Mice; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase | 2014 |
Identification of UshA as a major enzyme for NAD degradation in Escherichia coli.
Topics: 5'-Nucleotidase; Biocatalysis; Cell Membrane Permeability; Escherichia coli K12; Escherichia coli Proteins; Gene Deletion; Half-Life; Hydrolysis; NAD; Nicotinamide Mononucleotide; Periplasm; Phosphoric Diester Hydrolases; Pyrophosphatases; Recombinant Proteins | 2014 |
Complete steady-state rate equation for DNA ligase and its use for measuring product kinetic parameters of NAD⁺-dependent DNA ligase from Haemophilus influenzae.
Topics: Adenosine Monophosphate; DNA Ligase ATP; DNA Ligases; Haemophilus influenzae; Kinetics; Least-Squares Analysis; NAD; Nicotinamide Mononucleotide; Nonlinear Dynamics | 2014 |
Nicotinamide mononucleotide, an intermediate of NAD+ synthesis, protects the heart from ischemia and reperfusion.
Topics: Animals; Caloric Restriction; Cardiotonic Agents; Heart; Ischemic Preconditioning; Male; Mice; Myocardial Infarction; Myocardial Ischemia; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Reperfusion Injury; Sirtuin 1; Up-Regulation | 2014 |
Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the NAD(+) biosynthetic machinery in mammalian cells.
Topics: Animals; Biosynthetic Pathways; Cell Line; Cell-Free System; Enzyme Assays; Fluorometry; Humans; Liver; Mice; Mice, Inbred C57BL; NAD; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Organ Specificity; Pentosyltransferases; Phosphotransferases (Alcohol Group Acceptor) | 2014 |
Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism.
Topics: Animals; Binding Sites; Calorimetry; Chromatography, High Pressure Liquid; Cytokines; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria, Muscle; Muscle, Skeletal; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Oxidation-Reduction; Oxygen; Poly(ADP-ribose) Polymerases | 2015 |
Niacin receptor activation improves human microvascular endothelial cell angiogenic function during lipotoxicity.
Topics: Animals; Aorta; Apoptosis; Cattle; Cell Death; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Drug Combinations; Endothelial Cells; Gene Expression Regulation; Humans; Immunohistochemistry; Laminin; Lipids; Metabolic Syndrome; Microcirculation; NAD; Niacin; Nicotinamide Mononucleotide; Obesity; Protein Binding; Proteoglycans; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Nicotinic; RNA Interference; RNA, Small Interfering; Serum Albumin | 2014 |
NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms.
Topics: Acrylamides; Acute Disease; Animals; Astrocytes; Brain; Brain Injuries; Calcium-Binding Proteins; Cell Count; Chronic Disease; Cold Temperature; Cytokines; Disease Models, Animal; Macrophages; Male; Mice, Inbred BALB C; Microfilament Proteins; Microglia; NAD; Neurons; Neuroprotective Agents; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines | 2015 |
Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model.
Topics: Alzheimer Disease; Animals; Brain; Female; Male; Mice; Mice, Transgenic; Mitochondria; NAD; Neurodegenerative Diseases; Nicotinamide Mononucleotide; Oxygen Consumption | 2015 |
PARPs and ADP-Ribosylation: 50 Years … and Counting.
Topics: Adenosine Diphosphate Ribose; Biomedical Research; Biosynthetic Pathways; Forecasting; Humans; Interviews as Topic; Molecular Structure; NAD; Niacinamide; Nicotinamide Mononucleotide; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Time Factors | 2015 |
FK866 compromises mitochondrial metabolism and adaptive stress responses in cultured cardiomyocytes.
Topics: Acrylamides; Animals; Cells, Cultured; Cytokines; Gene Expression Regulation; Hydrogen Peroxide; Insulin; Mitochondria; Myocytes, Cardiac; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Norepinephrine; Piperidines; Rats; Stress, Physiological | 2015 |
Monocyte-derived extracellular Nampt-dependent biosynthesis of NAD(+) protects the heart against pressure overload.
Topics: Animals; Cytokines; Heart; Male; Mice; Mice, Inbred C57BL; Monocytes; Myocardium; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Protective Agents; Sirtuin 1; Up-Regulation | 2015 |
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.
Topics: 5'-Nucleotidase; Acrylamides; Adenosine Triphosphate; Animals; Cell Line, Tumor; Cytokines; Female; GPI-Linked Proteins; Humans; Mice; Mice, Nude; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Ovarian Neoplasms; Piperidines; Pyridinium Compounds; RNA Interference; RNA, Small Interfering | 2016 |
Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death.
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Death; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Memory; Mitochondria; NAD; Neurons; Neuroprotective Agents; Nicotinamide Mononucleotide; Peptide Fragments; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Tissue Culture Techniques | 2016 |
Auxotrophic Actinobacillus pleurpneumoniae grows in multispecies biofilms without the need for nicotinamide-adenine dinucleotide (NAD) supplementation.
Topics: Acetylglucosamine; Actinobacillus Infections; Actinobacillus pleuropneumoniae; Animals; Biofilms; Bordetella bronchiseptica; Culture Media; Deoxyribonuclease I; Endopeptidase K; Escherichia coli; In Situ Hybridization, Fluorescence; Microscopy, Confocal; NAD; Niacinamide; Nicotinamide Mononucleotide; Pasteurella multocida; Pyridines; Pyridinium Compounds; Species Specificity; Staphylococcus aureus; Stem Cells; Streptococcus suis; Swine; Swine Diseases | 2016 |
Independent AMP and NAD signaling regulates C2C12 differentiation and metabolic adaptation.
Topics: Acetylation; Adaptation, Physiological; Adenosine Monophosphate; Aminoimidazole Carboxamide; Animals; Cell Differentiation; Cell Line; Electron Transport Complex IV; Gene Expression Regulation; Glucose Transporter Type 1; Histones; Mice; Mitochondria; Myoblasts; Myosin Heavy Chains; NAD; Nicotinamide Mononucleotide; Ribonucleotides; Signal Transduction; Sirtuin 1 | 2016 |
Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia.
Topics: Animals; Brain Injuries; Brain Ischemia; Cell Death; Disease Models, Animal; Hippocampus; Male; Mice, Inbred C57BL; NAD; Niacinamide; Nicotinamide Mononucleotide | 2016 |
NAMPT-Mediated NAD(+) Biosynthesis Is Essential for Vision In Mice.
Topics: Animals; Cell Death; Cytokines; Diabetic Retinopathy; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Signal Transduction; Sirtuin 3; Sirtuins; Streptozocin; Vision, Ocular | 2016 |
β-Nicotinamide Mononucleotide, an Anti-Aging Candidate Compound, Is Retained in the Body for Longer than Nicotinamide in Rats.
Topics: Aging; Animals; Injections, Intraperitoneal; Longevity; Male; NAD; Niacinamide; Nicotinamide Mononucleotide; Rats; Rats, Wistar | 2016 |
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells.
Topics: Animals; Hep G2 Cells; Hepatocytes; Humans; Injections, Intraperitoneal; Mammals; Mice, Knockout; NAD; Niacinamide; Nicotinamide Mononucleotide; Phosphotransferases (Alcohol Group Acceptor); Pyridinium Compounds | 2016 |
Simultaneous quantitation of nicotinamide riboside, nicotinamide mononucleotide and nicotinamide adenine dinucleotide in milk by a novel enzyme-coupled assay.
Topics: Animals; Cattle; Enzyme Assays; Equidae; Fluorometry; Food Analysis; Food Handling; Humans; Milk; Milk, Human; NAD; Niacinamide; Nicotinamide Mononucleotide; Pasteurization; Pyridinium Compounds | 2017 |
Structural and Functional Characterization of Plasmodium falciparum Nicotinic Acid Mononucleotide Adenylyltransferase.
Topics: Catalytic Domain; Crystallography, X-Ray; Cysteine; Models, Molecular; NAD; NADP; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Plasmodium falciparum; Protein Conformation; Substrate Specificity; Surface Plasmon Resonance | 2016 |
Nicotinamide Mononucleotide, an NAD
Topics: Acute Kidney Injury; Age Factors; Animals; Disease Susceptibility; JNK Mitogen-Activated Protein Kinases; Mice; NAD; Nicotinamide Mononucleotide; Sirtuin 1 | 2017 |
Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway.
Topics: Animals; Biomarkers; Brain Injuries; Cell Death; Cerebral Hemorrhage; Disease Models, Animal; Heme Oxygenase-1; Immunohistochemistry; Inflammation Mediators; Mice; Microglia; NAD; Neuroprotection; Neutrophil Infiltration; NF-E2-Related Factor 2; Nicotinamide Mononucleotide; Oxidative Stress; Protective Agents; Signal Transduction; Time Factors | 2017 |
Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway.
Topics: Acrylamides; AMP-Activated Protein Kinases; Animals; Carbazoles; Cell Line; Cytokines; Diet, High-Fat; Enzyme Inhibitors; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Non-alcoholic Fatty Liver Disease; Oleic Acid; Piperidines; Resveratrol; Signal Transduction; Sirtuin 1; Sterol Regulatory Element Binding Protein 1; Stilbenes | 2017 |
Nicotinamide mononucleotide and related metabolites induce disease resistance against fungal phytopathogens in Arabidopsis and barley.
Topics: Arabidopsis; Disease Resistance; Flowers; Fusarium; Hordeum; NAD; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Plant Diseases; Plant Leaves; Plant Proteins; Salicylic Acid; Signal Transduction | 2017 |
NAD replenishment with nicotinamide mononucleotide protects blood-brain barrier integrity and attenuates delayed tissue plasminogen activator-induced haemorrhagic transformation after cerebral ischaemia.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Intracranial Hemorrhages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; NAD; Nicotinamide Mononucleotide; Tight Junction Proteins; Tissue Plasminogen Activator | 2017 |
Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure.
Topics: Acetylation; Animals; Cell Death; Fatty Acids; Heart Failure; Homeostasis; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Proteins; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Oxidation-Reduction; Pressure; Rats; Reactive Oxygen Species; Sirtuin 3 | 2017 |
Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells.
Topics: Acrylamides; Apoptosis; Cell Survival; Cytokines; Enzyme Inhibitors; Gene Expression; Hep G2 Cells; Hepatocytes; Humans; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Oleic Acid; Palmitic Acid; Piperidines; Primary Cell Culture; RNA, Messenger | 2017 |
Characterization and application of a novel nicotinamide mononucleotide adenylyltransferase from Thermus thermophilus HB8.
Topics: Enzyme Assays; Escherichia coli; NAD; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Tetrazolium Salts; Thermus thermophilus | 2018 |
Hyperthermophilic Archaeon Thermococcus kodakarensis Utilizes a Four-Step Pathway for NAD
Topics: Deamination; Hot Temperature; NAD; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinic Acids; Nucleotidyltransferases; Pentosyltransferases; Recombinant Proteins; Substrate Specificity; Thermococcus | 2018 |
Nicotinamide adenine dinucleotide is transported into mammalian mitochondria.
Topics: Animals; Biological Transport; Cell Line; HEK293 Cells; HL-60 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Mitochondria, Muscle; Myoblasts; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds | 2018 |
Loss of NAMPT in aging retinal pigment epithelium reduces NAD
Topics: Acrylamides; Aging; Animals; Cells, Cultured; Cytokines; Epithelial Cells; Gene Expression Regulation; Humans; Male; Mice; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction | 2018 |
Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH.
Topics: Acidosis; Acids; Adenosine Triphosphate; Animals; Cardiotonic Agents; Glucose; Glycolysis; Humans; Hydrogen-Ion Concentration; Mice; Myocardium; Myocytes, Cardiac; NAD; Naphthalenes; Nicotinamide Mononucleotide; Pyrones; Reperfusion Injury; Sirtuin 1; Sirtuin 3 | 2018 |
Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock.
Topics: Acidosis, Lactic; Adenosine Triphosphate; Animals; Cytokines; Hepatocytes; Humans; Inflammation; Interleukin-6; Kidney; Liver; Male; Mitochondria; Mitochondrial Diseases; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nicotinamide-Nucleotide Adenylyltransferase; Rats; Resuscitation; Shock, Hemorrhagic; Survival Analysis | 2018 |
Pharmacological bypass of NAD
Topics: Acrylamides; Animals; Antineoplastic Agents, Phytogenic; Drug Combinations; Francisella tularensis; Ganglia, Spinal; NAD; Nerve Degeneration; Neurons; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines; Pyridinium Compounds; Vincristine | 2018 |
Targeting NAD
Topics: Animals; Brain; Disease Models, Animal; Electron Transport Complex I; Female; Leigh Disease; Longevity; Male; Mice; Mice, Knockout; Mitochondria; Molecular Targeted Therapy; NAD; Nicotinamide Mononucleotide | 2019 |
Boosting NAD
Topics: A549 Cells; Animals; Biocatalysis; Enzyme Activators; Humans; Intracellular Space; Liver; Mice; Molecular Structure; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Phosphorylation; Small Molecule Libraries | 2019 |
Adipose tissue NAD
Topics: Adaptation, Physiological; Adipose Tissue, Brown; Animals; Caveolin 1; Cold Temperature; Cytokines; Energy Metabolism; Fasting; Homeostasis; Humans; Mice; Mice, Knockout; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Thermogenesis | 2019 |
Engineering a nicotinamide mononucleotide redox cofactor system for biocatalysis.
Topics: Biocatalysis; Carbon; Chromatography, Gas; Cyclohexanones; Escherichia coli; Kinetics; NAD; NADP; Nicotinamide Mononucleotide; Oxidation-Reduction; Protein Conformation; Protein Engineering; Pseudomonas putida; Ralstonia; Software | 2020 |
Nicotinamide mononucleotide ameliorates the depression-like behaviors and is associated with attenuating the disruption of mitochondrial bioenergetics in depressed mice.
Topics: Animals; Depression; Energy Metabolism; Mice; Mitochondria; NAD; Nicotinamide Mononucleotide | 2020 |
Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway.
Topics: Administration, Oral; Amides; Animals; Biosynthetic Pathways; Cell Line, Tumor; Cytokines; Energy Metabolism; Female; Gastrointestinal Microbiome; Humans; Male; Mammals; Metabolome; Mice, Inbred C57BL; Mycoplasma; NAD; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Pyridinium Compounds | 2020 |
Structural and Functional Characterization of NadR from
Topics: Amino Acid Sequence; Bacterial Proteins; Enzyme Activation; Kinetics; Lactococcus lactis; Models, Molecular; Molecular Conformation; NAD; Nicotinamide Mononucleotide; Protein Binding; Protein Interaction Domains and Motifs; Repressor Proteins; Structure-Activity Relationship; Substrate Specificity | 2020 |
Absence of evidence that Slc12a8 encodes a nicotinamide mononucleotide transporter.
Topics: Membrane Transport Proteins; NAD; Nicotinamide Mononucleotide | 2019 |
Reply to: Absence of evidence that Slc12a8 encodes a nicotinamide mononucleotide transporter.
Topics: Membrane Transport Proteins; NAD; Nicotinamide Mononucleotide | 2019 |
Metabolic engineering of Escherichia coli for optimized biosynthesis of nicotinamide mononucleotide, a noncanonical redox cofactor.
Topics: Biocatalysis; Biosynthetic Pathways; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Industrial Microbiology; Metabolic Engineering; Mutation; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction | 2020 |
Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes.
Topics: Aging; Animals; Apoptosis; Cellular Senescence; Chromosomes, Mammalian; Cytoplasmic Granules; Dietary Supplements; DNA Damage; Embryonic Development; Female; Fertilization; Kinetochores; Male; Meiosis; Metalloproteases; Mice, Inbred ICR; Microtubules; Mitochondria; NAD; Nicotinamide Mononucleotide; Oocytes; Reactive Oxygen Species; Spermatozoa; Spindle Apparatus; Transcriptome | 2020 |
Structural and Mechanistic Regulation of the Pro-degenerative NAD Hydrolase SARM1.
Topics: Animals; Armadillo Domain Proteins; Cell Death; Cell Line, Tumor; Cryoelectron Microscopy; Cytoskeletal Proteins; Female; HEK293 Cells; Humans; Mice, Inbred C57BL; Models, Molecular; NAD; Neurons; Nicotinamide Mononucleotide; Protein Domains | 2020 |
Physical exercise may exert its therapeutic influence on Alzheimer's disease through the reversal of mitochondrial dysfunction via SIRT1-FOXO1/3-PINK1-Parkin-mediated mitophagy.
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Brain-Derived Neurotrophic Factor; Disease Progression; Exercise; Forkhead Box Protein O1; Humans; Mitochondria; Mitochondrial Diseases; Mitophagy; NAD; Niacinamide; Nicotinamide Mononucleotide; Protein Kinases; Pyridinium Compounds; Reactive Oxygen Species; Sirtuin 1; Ubiquitin-Protein Ligases | 2021 |
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD
Topics: Adipocytes, White; Adipose Tissue, White; ADP-ribosyl Cyclase 1; Aging; Animals; Bone Marrow Transplantation; Cellular Senescence; HEK293 Cells; Humans; Inflammation; Liver; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NAD; Nicotinamide Mononucleotide; Phenotype | 2020 |
Metabolic design for selective production of nicotinamide mononucleotide from glucose and nicotinamide.
Topics: Biosynthetic Pathways; Escherichia coli; Glucose; NAD; Niacinamide; Nicotinamide Mononucleotide | 2021 |
Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment.
Topics: Animals; Apoptosis; CD11b Antigen; Cell Line; Glial Fibrillary Acidic Protein; Heme Oxygenase-1; In Situ Nick-End Labeling; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; NAD; Neuroprotective Agents; Nicotinamide Mononucleotide; Oxidative Stress; Photoreceptor Cells, Vertebrate; Protein Carbonylation; Retinal Degeneration; Retinal Detachment; Sirtuin 1 | 2020 |
Equilibrative Nucleoside Transporters Mediate the Import of Nicotinamide Riboside and Nicotinic Acid Riboside into Human Cells.
Topics: Aging; Cytosol; Equilibrative Nucleoside Transport Proteins; HEK293 Cells; Humans; Magnetic Resonance Spectroscopy; Membrane Transport Proteins; Metabolomics; NAD; Niacinamide; Nicotinamide Mononucleotide; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pyridinium Compounds; Recombinant Proteins; Ribonucleosides | 2021 |
Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD
Topics: Animals; Cell Cycle; Citric Acid Cycle; Glycolysis; Mice; NAD; Nicotinamide Mononucleotide | 2021 |
Pre-emptive Short-term Nicotinamide Mononucleotide Treatment in a Mouse Model of Diabetic Nephropathy.
Topics: Albuminuria; Animals; Claudin-1; Cytokines; Diabetic Nephropathies; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; Dose-Response Relationship, Drug; Epigenesis, Genetic; Glomerular Mesangium; Glycated Hemoglobin; Histones; Male; Mice; Mice, Knockout; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nicotinamide-Nucleotide Adenylyltransferase; Podocytes; Sirtuin 1; Survival Rate; Time Factors | 2021 |
Inhibition of nicotinamide phosphoribosyltransferase protects against acute pancreatitis via modulating macrophage polarization and its related metabolites.
Topics: Acute Disease; Animals; Ceruletide; Cytokines; Macrophages; Mice; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Pancreatitis; Sirtuin 1 | 2021 |
Sex-specific alterations in NAD+ metabolism in 3xTg Alzheimer's disease mouse brain assessed by quantitative targeted LC-MS.
Topics: Alzheimer Disease; Animals; Chromatography, High Pressure Liquid; Encephalitis; Female; Humans; Kynurenic Acid; Kynurenine; Male; Metabolome; Mice; Mice, Transgenic; NAD; Neuroprotection; Nicotinamide Mononucleotide; Sex Characteristics; Tandem Mass Spectrometry | 2021 |
Metabolic engineering of Escherichia coli for biosynthesis of β-nicotinamide mononucleotide from nicotinamide.
Topics: Escherichia coli; Metabolic Engineering; NAD; Niacinamide; Nicotinamide Mononucleotide | 2021 |
Supplementing media with NAD
Topics: Animals; Culture Media; Embryonic Development; In Vitro Oocyte Maturation Techniques; NAD; Niacin; Nicotinamide Mononucleotide; Swine | 2021 |
Nicotinamide mononucleotide: a potential effective natural compound against insulin resistance.
Topics: Biological Products; Female; Humans; Insulin; Insulin Resistance; NAD; Nicotinamide Mononucleotide; Overweight; Randomized Controlled Trials as Topic | 2021 |
[Determination of β-nicotinamide mononucleotide and nicotinamide adenine dinucleotide in Dendrobium officinale and congeneric species by UPLC-MS/MS].
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Dendrobium; NAD; Nicotinamide Mononucleotide; Tandem Mass Spectrometry | 2021 |
Nicotinamide mononucleotide augments the cytotoxic activity of natural killer cells in young and elderly mice.
Topics: Aging; Animals; Killer Cells, Natural; Mice; Mice, Inbred BALB C; NAD; Nicotinamide Mononucleotide | 2021 |
Biosynthesis of a Therapeutically Important Nicotinamide Mononucleotide through a Phosphoribosyl Pyrophosphate Synthetase 1 and 2 Engineered Strain of
Topics: Biosynthetic Pathways; Escherichia coli; Glucose; Metabolic Engineering; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotides; Ribose-Phosphate Pyrophosphokinase | 2021 |
Mitochondria metabolomics reveals a role of β-nicotinamide mononucleotide metabolism in mitochondrial DNA replication.
Topics: DNA, Mitochondrial; HEK293 Cells; Humans; Metabolomics; Mitochondria; NAD; Nicotinamide Mononucleotide | 2022 |
Nicotinamide Mononucleotide Prevents Free Fatty Acid-Induced Reduction in Glucose Tolerance by Decreasing Insulin Clearance.
Topics: Animals; Fatty Acids, Nonesterified; Glucose; Glucose Intolerance; Hep G2 Cells; Humans; Infusions, Intravenous; Insulin; Male; Mice; Mice, Inbred C57BL; NAD; Nicotinamide Mononucleotide; Oleic Acid; Sirtuin 1; Up-Regulation | 2021 |
NAD supplementation improves mitochondrial performance of cardiolipin mutants.
Topics: Barth Syndrome; Cardiolipins; Dietary Supplements; Humans; Mitochondria; NAD; Nicotinamide Mononucleotide | 2022 |
Nicotinamide mononucleotide promotes pancreatic islet function through the SIRT1 pathway in mice after severe burns.
Topics: Animals; Burns; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; NAD; Nicotinamide Mononucleotide; Sirtuin 1 | 2022 |
Multispectral autofluorescence characteristics of reproductive aging in old and young mouse oocytes.
Topics: Aging; Animals; Female; Fertility; Mice; NAD; Nicotinamide Mononucleotide; Oocytes | 2022 |
Intestinal Epithelial NAD+ Biosynthesis Regulates GLP-1 Production and Postprandial Glucose Metabolism in Mice.
Topics: Animals; Cytokines; Glucagon-Like Peptide 1; Glucose; Mice; NAD; Nicotinamide Mononucleotide; Postprandial Period | 2022 |
Insights into the NAD
Topics: Animals; Cattle; Hydrolyzable Tannins; Meiosis; Mice; NAD; Niacin; Nicotinamide Mononucleotide; Oocytes; Swine | 2022 |
Synthesis of Nicotinamide Mononucleotide from Xylose via Coupling Engineered Escherichia coli and a Biocatalytic Cascade.
Topics: Escherichia coli; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nucleotides; Ribose; Xylose | 2022 |
Distribution of Nicotinamide Mononucleotide after Intravenous Injection in Normal and Ischemic Stroke Mice.
Topics: Animals; Injections, Intravenous; Ischemic Stroke; Mice; NAD; Nicotinamide Mononucleotide | 2023 |
Nicotinamide Mononucleotide Administration Amends Protein Acetylome of Aged Mouse Liver.
Topics: Animals; Chromatography, Liquid; Liver; Mice; NAD; Nicotinamide Mononucleotide; Tandem Mass Spectrometry | 2022 |
Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells.
Topics: Aging; Animals; Antioxidants; Cellular Senescence; Claudin-1; Dietary Supplements; Galactose; Mice; NAD; Nicotinamide Mononucleotide; Occludin; RNA, Messenger; Sirtuins | 2022 |
NAD + salvage governs mitochondrial metabolism, invigorating natural killer cell antitumor immunity.
Topics: Animals; Carcinoma, Hepatocellular; Cytokines; Humans; Killer Cells, Natural; Liver Neoplasms; Mice; NAD; Nicotinamide Mononucleotide; Tumor Microenvironment | 2023 |
Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.
Topics: Cellular Senescence; Humans; Inflammation; Iodates; Macular Degeneration; NAD; Nicotinamide Mononucleotide; Oxidative Stress; Retinal Pigment Epithelium | 2022 |
Quantitative Acetylomics Reveals Dynamics of Protein Lysine Acetylation in Mouse Livers During Aging and Upon the Treatment of Nicotinamide Mononucleotide.
Topics: Acetylation; Animals; Liver; Lysine; Mammals; Mice; NAD; Nicotinamide Mononucleotide; Sirtuins | 2022 |
Topics: Aged; Animals; Antipsychotic Agents; Arabinose; Cell Wall; Cohort Studies; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Dimyristoylphosphatidylcholine; Electron Transport; Escherichia coli; Female; Ferroptosis; Fibroblasts; Flour; Humans; Indicators and Reagents; Inulin; Ligands; Lipid Bilayers; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Medicare; Membrane Proteins; Mice; NAD; NADPH-Ferrihemoprotein Reductase; Nanostructures; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nursing Homes; Pain; Palladium; Phospholipids; Pressure Ulcer; Spectroscopy, Fourier Transform Infrared; Sulfhydryl Compounds; Triticum; United States; Water; Xylans; Xylose | 2021 |
Nicotinamide Mononucleotide Alleviates Osteoblast Senescence Induction and Promotes Bone Healing in Osteoporotic Mice.
Topics: Animals; Humans; Mice; NAD; Nicotinamide Mononucleotide; Osteoblasts; Osteogenesis; Osteoporosis; Tumor Necrosis Factor-alpha | 2023 |
Declining muscle NAD
Topics: Animals; Dihydrotestosterone; Female; Humans; Hyperandrogenism; Insulin Resistance; Lipids; Metabolic Syndrome; Mice; Muscle, Skeletal; NAD; Nicotinamide Mononucleotide; Obesity; Polycystic Ovary Syndrome | 2022 |
An artificial multi-enzyme cascade biocatalysis for biomanufacturing of nicotinamide mononucleotide from starch and nicotinamide in one-pot.
Topics: Biocatalysis; NAD; Niacinamide; Nicotinamide Mononucleotide; Prospective Studies; Starch | 2023 |
Enhancing the biosynthesis of nicotinamide mononucleotide in Lactococcus lactis by heterologous expression of FtnadE.
Topics: Lactococcus lactis; NAD; Niacinamide; Nicotinamide Mononucleotide | 2023 |
Effects of Combined Treatment with Compounds Affecting Mitochondria on Physiological Parameters in Old Monkey.
Topics: Animals; Antioxidants; Male; Mitochondria; NAD; Nicotinamide Mononucleotide | 2022 |
Gut microbiota-derived nicotinamide mononucleotide alleviates acute pancreatitis by activating pancreatic SIRT3 signalling.
Topics: Acute Disease; Animals; Ceruletide; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Mice; NAD; Nicotinamide Mononucleotide; Pancreatitis; Rats; Sirtuin 3 | 2023 |
Oxidative degradation of dihydrofolate reductase increases CD38-mediated ferroptosis susceptibility.
Topics: Animals; Ferroptosis; Mice; NAD; Nicotinamide Mononucleotide; Oxidative Stress; Reactive Oxygen Species; Tetrahydrofolate Dehydrogenase | 2022 |
Porcine placental extract increase the cellular NAD levels in human epidermal keratinocytes.
Topics: Animals; Epidermis; Female; Humans; Keratinocytes; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Placenta; Placental Extracts; Pregnancy; Swine | 2022 |
The NAD
Topics: Animals; Armadillo Domain Proteins; Axons; Cytoskeletal Proteins; Drosophila; Mammals; Mice; NAD; Neurons; Nicotinamide Mononucleotide | 2022 |
Nicotinamide Mononucleotide Alleviates Angiotensin II-Induced Human Aortic Smooth Muscle Cell Senescence in a Microphysiological Model.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Humans; Myocytes, Smooth Muscle; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase | 2023 |
NMN Alleviates NP-Induced Learning and Memory Impairment Through SIRT1 Pathway in PC-12 Cell.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cholinergic Agents; NAD; Nicotinamide Mononucleotide; PC12 Cells; Rats; Serotonin; Sirtuin 1 | 2023 |
Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high-fat diet.
Topics: Animals; Body Composition; Diet, High-Fat; Metabolic Diseases; Mice; NAD; Nicotinamide Mononucleotide; Obesity; Sirtuins | 2023 |
Nicotinamide mononucleotides alleviated neurological impairment via anti-neuroinflammation in traumatic brain injury.
Topics: Animals; Brain Injuries, Traumatic; NAD; Niacinamide; Nicotinamide Mononucleotide; Rats; Toll-Like Receptor 2 | 2023 |
Preparation and evaluation of ovalbumin-fucoidan nanoparticles for nicotinamide mononucleotide encapsulation with enhanced stability and anti-aging activity.
Topics: NAD; Nanoparticles; Nicotinamide Mononucleotide; Ovalbumin; Polysaccharides | 2023 |
Reversing Acute Kidney Injury through Coordinated Interplay of Anti-Inflammation and Iron Supplementation.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents; Dietary Supplements; Humans; NAD; Nicotinamide Mononucleotide; Reactive Oxygen Species | 2023 |
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.
Topics: Autophagy; Humans; Mitochondria; NAD; Neurons; Niacinamide; Nicotinamide Mononucleotide | 2023 |
Nicotinamide mononucleotide supplementation mitigates osteopenia induced by modeled microgravity in rats.
Topics: Animals; Bone Density; Bone Diseases, Metabolic; Dietary Supplements; NAD; Nicotinamide Mononucleotide; Rats; Weightlessness | 2023 |
β-Nicotinamide mononucleotide activates NAD+/SIRT1 pathway and attenuates inflammatory and oxidative responses in the hippocampus regions of septic mice.
Topics: Animals; Brain Ischemia; Hippocampus; Lipopolysaccharides; Mice; NAD; Nicotinamide Mononucleotide; Oxidative Stress; Sepsis; Sirtuin 1 | 2023 |
Nicotinamide mononucleotide (NMN) intake increases plasma NMN and insulin levels in healthy subjects.
Topics: Healthy Volunteers; Humans; Insulins; NAD; Nicotinamide Mononucleotide; Sirtuin 1 | 2023 |
Triple-Isotope Tracing for Pathway Discernment of NMN-Induced NAD
Topics: Aging; Animals; Biological Transport; Humans; Mice; NAD; Nicotinamide Mononucleotide | 2023 |
Host-microbiome interactions in nicotinamide mononucleotide (NMN) deamidation.
Topics: Animals; Anti-Bacterial Agents; Mammals; Microbiota; NAD; Nicotinamide Mononucleotide | 2023 |
Nicotinamide mononucleotide (NMN) alleviates the poly(I:C)-induced inflammatory response in human primary cell cultures.
Topics: Bayes Theorem; Endothelial Cells; Humans; Inflammation; NAD; Nicotinamide Mononucleotide; Primary Cell Culture | 2023 |
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity.
Topics: Animals; Kinetics; Mammals; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Phosphorylation | 2023 |
Fingerstick blood assay maps real-world NAD
Topics: Aging; Female; Humans; Male; NAD; Nicotinamide Mononucleotide; Pyridinium Compounds | 2023 |
NAD
Topics: Adolescent; Adult; Aged; Aged, 80 and over; COVID-19; Endothelial Cells; Female; Humans; Male; Middle Aged; NAD; Nicotinamide Mononucleotide; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; SARS-CoV-2; Young Adult | 2023 |
A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels.
Topics: Armadillo Domain Proteins; Axons; Cell Line; Humans; Hydrolases; NAD; Neurons; Nicotinamide Mononucleotide | 2023 |
Improving lysosomal ferroptosis with NMN administration protects against heart failure.
Topics: Animals; Ferroptosis; Heart Failure; Mice; Mitochondria; NAD; Nicotinamide Mononucleotide | 2023 |
The Combination of Citicoline and Nicotinamide Mononucleotide Induces Neurite Outgrowth and Mitigates Vascular Cognitive Impairment via SIRT1/CREB Pathway.
Topics: Animals; Cognitive Dysfunction; Cytidine Diphosphate Choline; Dementia, Vascular; NAD; Neuroinflammatory Diseases; Neuronal Outgrowth; Nicotinamide Mononucleotide; Rats; Sirtuin 1 | 2023 |
A holistic approach for process intensification of nicotinamide mononucleotide production via high cell density cultivation under exponential feeding strategy.
Topics: Batch Cell Culture Techniques; Bioreactors; Glucose; NAD; Niacinamide; Nicotinamide Mononucleotide | 2023 |
Nicotinamide mononucleotide as a therapeutic agent to alleviate multi-organ failure in sepsis.
Topics: Animals; Endothelial Cells; Inflammation; Mice; Mitochondrial Diseases; NAD; Nicotinamide Mononucleotide; Sepsis; Sirtuin 3 | 2023 |
Dehydrogenase binding by tiazofurin anabolites.
Topics: Adenine Nucleotides; Antineoplastic Agents; Binding, Competitive; Computer Simulation; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Models, Chemical; Oxidoreductases; Ribavirin; Ribonucleosides | 1990 |
Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Binding Sites; Biophysical Phenomena; Biophysics; Calorimetry; Escherichia coli; Ligands; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nucleotides; Protein Binding; Structure-Activity Relationship; Thermodynamics | 2006 |