nad has been researched along with mycophenolic acid in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 7 (30.43) | 18.2507 |
| 2000's | 10 (43.48) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hedstrom, L; Wang, CC | 1 |
| Azzolina, BA; Behrens, ND; Hupe, DJ | 1 |
| Scrimgeour, KG; Wu, TW | 1 |
| Anderson, WK; Kajtár-Peredy, M; Keserû, GM; Makara, GM | 1 |
| Bruzzese, FJ; Chambers, SP; Connelly, PR; Fleming, MA; Fox, T; Fulghum, JR; Hoe, ST; Livingston, DJ; Nimmesgern, E; Sintchak, MD; Stuver, CM; Thomson, JA; Wilson, KP | 1 |
| Hoyt, JC; Parry, RJ | 1 |
| Goldstein, BM; Lesiak, K; Majumdar, A; Pankiewicz, KW; Powell, J; Seidman, M; Vanderveen, K; Watanabe, KA | 1 |
| Digits, JA; Hedstrom, L | 2 |
| Lesiak-Watanabe, K; Malinowski, K; Pankiewicz, KW; Watanabe, KA | 1 |
| Nimmesgern, E; Sintchak, MD | 1 |
| Daxecker, H; Müller, MM; Raab, M | 1 |
| Luecke, H; Prosise, GL | 1 |
| Clark, JL; Lostia, S; Otto, MJ; Pankiewicz, KW; Patterson, SE; Stuyver, LJ; Watanabe, KA | 1 |
| Black, PL; Goldstein, BM; Jayaram, HN; Pankiewicz, KW; Patterson, SE; Risal, D; Schinazi, RF; Stuyver, LJ | 1 |
| Anderson, WK; Bernacki, RJ; El-Araby, ME; Makara, GM; Pera, PJ | 1 |
| Berg, A; Boitz, JM; Dobie, F; Jardim, A | 1 |
| Bennett, EM; Bonnac, L; Chen, L; Felczak, K; Gao, G; Hedstrom, L; Jayaram, HN; Pankiewicz, KW; Patterson, SE; Wilson, D | 1 |
| Brandhorst, G; Coffing, MJ; Domke, I; Liebisch, G; Luthe, H; Marquet, P; Oellerich, M; Schmitz, G; Shaw, LM; Streit, F | 1 |
| Anderson, WF; Binkowski, TA; Gollapalli, DR; Gornicki, P; Hedstrom, L; Jedrzejczak, R; Joachimiak, A; Kim, Y; Kuhn, ML; Mack, JC; Makowska-Grzyska, M; Maltseva, N; Mulligan, R; Wang, XK; Wilton, R; Wu, R; Zhang, R | 1 |
| Luvisi, A; Panattoni, A; Rinaldelli, E; Triolo, E | 1 |
| Bessho, T; Djikeng, A; Duszenko, M; Inui, T; Kubata, KB; Kusumoto, T; Martin, SK; Morii, S; Nishimura, S; Noda, M; Shinohara, T; Shuto, S; Uchiyama, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
2 review(s) available for nad and mycophenolic acid
| Article | Year |
|---|---|
The structure of inosine 5'-monophosphate dehydrogenase and the design of novel inhibitors.
Topics: Animals; Autoimmune Diseases; Drug Design; Enzyme Inhibitors; Guanine Nucleotides; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Mycophenolic Acid; NAD | 2000 |
Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target.
Topics: Catalysis; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Molecular Mimicry; Molecular Structure; Mycophenolic Acid; NAD; Ribavirin; Ribonucleosides | 2004 |
21 other study(ies) available for nad and mycophenolic acid
| Article | Year |
|---|---|
Mycophenolic acid and thiazole adenine dinucleotide inhibition of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: implications on enzyme mechanism.
Topics: Adenine Nucleotides; Animals; Binding Sites; Binding, Competitive; IMP Dehydrogenase; Isomerism; Ketone Oxidoreductases; Kinetics; Mycophenolic Acid; NAD; Ribonucleotides; Tritrichomonas; Xanthine | 1990 |
IMP dehydrogenase from the intracellular parasitic protozoan Eimeria tenella and its inhibition by mycophenolic acid.
Topics: Animals; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Eimeria; Humans; Hypoxanthine Phosphoribosyltransferase; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Liver; Lymphoma; Models, Chemical; Mycophenolic Acid; NAD; Placenta; Rats; Sarcoma 180 | 1986 |
Properties of inosinic acid dehydrogenase from Bacillus subtilis. II. Kinetic properties.
Topics: Adenosine Monophosphate; Bacillus subtilis; Binding Sites; Binding, Competitive; Catalysis; Cations, Monovalent; Enzyme Activation; Feedback; Guanine Nucleotides; Hot Temperature; Hydrogen-Ion Concentration; Inosine Nucleotides; Ketone Oxidoreductases; Kinetics; Mycophenolic Acid; NAD; Osmolar Concentration; Potassium | 1973 |
Nuclear magnetic resonance and molecular modeling study on mycophenolic acid: implications for binding to inosine monophosphate dehydrogenase.
Topics: Enzyme Inhibitors; IMP Dehydrogenase; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Mycophenolic Acid; NAD | 1996 |
Inhibition of IMPDH by mycophenolic acid: dissection of forward and reverse pathways using capillary electrophoresis.
Topics: Animals; Base Sequence; Cricetinae; Crystallization; DNA Primers; Electrophoresis, Capillary; Enzyme Inhibitors; Escherichia coli; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Chemical; Molecular Sequence Data; Mycophenolic Acid; NAD; Protein Binding; Recombinant Proteins | 1996 |
Purification and preliminary characterization of (E)-3-(2,4-dioxo-6-methyl-5-pyrimidinyl)acrylic acid synthase, an enzyme involved in biosynthesis of the antitumor agent sparsomycin.
Topics: Acrylates; Amino Acids; Antibiotics, Antineoplastic; Cations; Diethyl Pyrocarbonate; Hypoxanthines; Isoelectric Point; Kinetics; Molecular Weight; Mycophenolic Acid; NAD; Oxygenases; Purines; Pyrimidinones; Sparsomycin; Streptomyces; Substrate Specificity; Sulfhydryl Reagents | 1997 |
Synthesis of a methylenebis(phosphonate) analogue of mycophenolic adenine dinucleotide: a glucuronidation-resistant MAD analogue of NAD.
Topics: Adenine Nucleotides; Antineoplastic Agents; Biotransformation; Cell Division; Glucuronates; Glucuronosyltransferase; Humans; IMP Dehydrogenase; Indicators and Reagents; Molecular Structure; Mycophenolic Acid; NAD; Structure-Activity Relationship; Tumor Cells, Cultured | 1998 |
Kinetic mechanism of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cysteine; Deuterium; Humans; IMP Dehydrogenase; Kinetics; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Mycophenolic Acid; NAD; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Tritrichomonas foetus | 1999 |
Novel mycophenolic adenine bis(phosphonate)s as potential immunosuppressants.
Topics: Dose-Response Relationship, Drug; HT29 Cells; Humans; Immunosuppressive Agents; IMP Dehydrogenase; K562 Cells; Kinetics; Mycophenolic Acid; NAD | 1999 |
Drug selectivity is determined by coupling across the NAD+ site of IMP dehydrogenase.
Topics: Adenosine Diphosphate; Animals; Cricetinae; Cricetulus; Drug Resistance; Drug Synergism; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Mutagenesis, Site-Directed; Mycophenolic Acid; NAD; Ribavirin; Spectrometry, Fluorescence; Tritrichomonas foetus; Tryptophan | 2000 |
Influence of mycophenolic acid on inosine 5'-monophosphate dehydrogenase activity in human peripheral blood mononuclear cells.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Indicators and Reagents; Kinetics; Monocytes; Mycophenolic Acid; NAD; Spectrophotometry, Ultraviolet | 2002 |
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
Topics: Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Mycophenolic Acid; NAD; Protein Conformation; Ribavirin; Ribonucleotides; Tritrichomonas foetus; Xanthine | 2003 |
Inhibitors of the IMPDH enzyme as potential anti-bovine viral diarrhoea virus agents.
Topics: Animals; Cattle; Cell Line; Computer Systems; Culture Media, Conditioned; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Guanosine Triphosphate; IMP Dehydrogenase; Kidney; Molecular Structure; Mycophenolic Acid; NAD; Nucleosides; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; Ribonucleosides; Viral Plaque Assay; Virus Replication | 2002 |
Synthesis, molecular modeling, and evaluation of nonphenolic indole analogs of mycophenolic acid.
Topics: Animals; Binding Sites; Cell Line, Tumor; Cricetinae; Humans; IMP Dehydrogenase; Indoles; Models, Molecular; Mycophenolic Acid; NAD; Structure-Activity Relationship | 2004 |
Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.
Topics: Amino Acid Sequence; Animals; Enzyme Inhibitors; Escherichia coli; Guanosine Monophosphate; Inosine Monophosphate; Leishmania donovani; Microbodies; Microscopy, Confocal; Mycophenolic Acid; NAD; Peroxisome-Targeting Signal 1 Receptor; Phylogeny; Protein Binding; Protozoan Proteins; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Ribonucleotides; Sequence Alignment; Subcellular Fractions; Substrate Specificity; Xanthine | 2007 |
Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues.
Topics: Adenosine Monophosphate; Antineoplastic Agents; Diphosphonates; Drug Screening Assays, Antitumor; Humans; IMP Dehydrogenase; Isoenzymes; K562 Cells; Models, Molecular; Mycophenolic Acid; NAD; Protein Binding; Ribavirin | 2007 |
Multicenter evaluation of a new inosine monophosphate dehydrogenase inhibition assay for quantification of total mycophenolic acid in plasma.
Topics: Antibody Specificity; Chromatography, High Pressure Liquid; Cross Reactions; Drug Monitoring; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Inosine Monophosphate; Mass Spectrometry; Mycophenolic Acid; NAD; Reproducibility of Results | 2008 |
Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
Topics: Amino Acid Sequence; Apoenzymes; Bacillus anthracis; Benzimidazoles; Catalytic Domain; Enzyme Inhibitors; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Mycophenolic Acid; NAD; Protein Binding; Ribonucleotides; Triazoles; Xanthine | 2012 |
Effect of mycophenolic acid on trans-plasma membrane electron transport and electric potential in virus-infected plant tissue.
Topics: Analysis of Variance; Antiviral Agents; Cell Membrane; Cucumovirus; Electron Transport; Enzyme Inhibitors; Membrane Potentials; Mycophenolic Acid; NAD; Nicotiana; Plant Diseases; Plant Leaves | 2012 |
Characterization of the novel Trypanosoma brucei inosine 5'-monophosphate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Escherichia coli; Humans; Hydrogen-Ion Concentration; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Mycophenolic Acid; NAD; Nucleotides; Protein Multimerization; Recombinant Proteins; Ribonucleosides; Sequence Alignment; Trypanosoma brucei brucei | 2013 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |