Page last updated: 2024-08-17

nad and metyrapone

nad has been researched along with metyrapone in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199019 (73.08)18.7374
1990's4 (15.38)18.2507
2000's2 (7.69)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belvedere, G; Cantoni, L; Garattini, S; Mussini, E; Pachecka, J; Salmona, M1
Klinger, W; Muller, D1
Prochukhanov, RA; Rostovtseva, TI1
Freeman, JJ; Hayes, EP1
Franklin, MR1
Illing, HP; Kunke, S; Netter, KJ1
Dean, PD; Whitehouse, MW1
Kahl, GF; Simon, S1
Sauer, LA1
Kahl, GG; Netter, KJ; Simon, S1
Illing, HP; Netter, KJ1
Dorfman, RI; Raman, PB; Sharma, DC1
Harding, BW; Oldham, SB; Wilson, LD1
Brauser, B; Sies, H1
Dal Pra, P; Melosi, P; Rossini, L1
Porter, WR; Trager, WF; Wheeler, C1
Garattini, E; Gazzotti, G; Salmona, M1
Hollenberg, PF; Koop, DR1
Chen, H; Juchau, MR; Namkung, MJ1
Liu, W; Rosazza, JP1
Maser, E1
Bland, TJ; Robertson, IG1
Gille, L; Nohl, H1
FERRARI, E; GHIRINGHELLI, F; PIOTTI, LE1
Lin, CH; Lin, PH1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1

Other Studies

26 other study(ies) available for nad and metyrapone

ArticleYear
Microsomal styrene mono-oxygenase and styrene epoxide hydrase activities in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1976, Volume: 6, Issue:10

    Topics: Animals; Brain; Carbamazepine; Epoxide Hydrolases; Female; Hydro-Lyases; Kidney; Lung; Male; Methylcholanthrene; Metyrapone; Microsomes; Microsomes, Liver; Myocardium; NAD; NADP; Organ Specificity; Oxygenases; Phenobarbital; Proadifen; Rats; Sex Factors; Spleen; Styrenes

1976
Developmental aspects of xenobiotic transformation.
    Environmental health perspectives, 1976, Volume: 18

    Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Ethylmorphine; Female; Glucosephosphates; Hexobarbital; Hydrogen-Ion Concentration; Metyrapone; Microsomes, Liver; NAD; NADP; Niacinamide; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenobarbital; Pregnancy; Rats; Semicarbazides

1976
[Structuro-metabolic mechanisms for integrating several endocrine organs].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1979, Volume: 65, Issue:1

    Topics: 11-Hydroxycorticosteroids; Adrenal Cortex; Adrenocorticotropic Hormone; Alkaline Phosphatase; Animals; Estrus; Female; Histocytochemistry; Hydroxysteroid Dehydrogenases; Metyrapone; NAD; NADP; Pituitary Gland, Anterior; Pregnancy; Rats

1979
Microsomal metabolism of acetonitrile to cyanide. Effects of acetone and other compounds.
    Biochemical pharmacology, 1988, Mar-15, Volume: 37, Issue:6

    Topics: Acetone; Acetonitriles; Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Ethanol; Female; Metyrapone; Microsomes, Liver; NAD; Proadifen; Proteins; Rats; Rats, Inbred Strains; Time Factors

1988
Piperonyl butoxide metabolism by cytochrome P-450: factors affecting the formation and disappearance of the metabolite-cytochrome P-450 complex.
    Xenobiotica; the fate of foreign compounds in biological systems, 1972, Volume: 2, Issue:6

    Topics: Animals; Cysteamine; Cytochrome P-450 Enzyme System; Dioxoles; Glucuronates; Hexobarbital; Kinetics; Male; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Pesticide Synergists; Piperonyl Butoxide; Protein Binding; Rats; S-Adenosylmethionine; Spectrophotometry; Uridine Diphosphate Sugars

1972
On the spectral intermediate at 440 nm formed during mixed function substrate oxidation.
    Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18

    Topics: Acetanilides; Aniline Compounds; Animals; Barbiturates; Cytochrome P-450 Enzyme System; Desipramine; Imipramine; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pentobarbital; Proadifen; Protein Binding; Rats; Spectrophotometry, Ultraviolet

1974
The effects of mepyrapone (SU 4885) and some hypercholesterolaemic drugs on hepatic sterol and fatty acid oxidation.
    Biochemical pharmacology, 1967, Volume: 16, Issue:3

    Topics: Animals; Anticholesteremic Agents; Carnitine; Cattle; Cholesterol; Drug Antagonism; Fatty Acids; Female; Liver; Male; Metyrapone; Mice; Mitochondria; Myocardium; NAD; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Rats; Sterols; Triparanol

1967
Action of metyrapone on the redox state of free nicotinamide-adenine dinucleotide and on oxygen consumption of perfused rat livers and isolated mitochondria.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 268, Issue:1

    Topics: Acetoacetates; Animals; Depression, Chemical; Electron Transport; Ferrocyanides; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; In Vitro Techniques; Kinetics; Lactates; Liver; Male; Metyrapone; Mitochondria, Liver; NAD; Oxygen Consumption; Perfusion; Polarography; Pyruvates; Rats; Spectrophotometry

1971
Steroid hydroxylations in rat adrenal mitochondria. II. Competition between energy-linked transhydrogenase-dependent steroid hydroxylation and oxidative phosphorylation for high-energy intermediates and NADH.
    Archives of biochemistry and biophysics, 1970, Volume: 139, Issue:2

    Topics: Adenosine Triphosphate; Adrenal Glands; Animals; Corticosterone; Desoxycorticosterone; Electron Transport; Hydroxybutyrates; Ketoglutaric Acids; Male; Malonates; Metyrapone; Mitochondria; NAD; Oxidative Phosphorylation; Oxidoreductases; Rats

1970
[Influence of metyrapone on redox state and oxygen consumption of isolated perfused rat livers].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 266, Issue:4

    Topics: Animals; Depression, Chemical; In Vitro Techniques; Liver; Metyrapone; Mitochondria, Liver; NAD; Oxygen Consumption; Perfusion; Rats

1970
Kinetic experiments on the synergistic effect of NADH on microsomal drug oxidation.
    Xenobiotica; the fate of foreign compounds in biological systems, 1974, Volume: 4, Issue:9

    Topics: Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Chloromercuribenzoates; Drug Synergism; Hexobarbital; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NAD; Nitro Compounds; Oxidation-Reduction; Oxygen Consumption; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Phenols; Proadifen; Pyridines; Rats; Spectrophotometry

1974
Studies on aldosterone biosynthesis in vitro.
    Biochemistry, 1966, Volume: 5, Issue:6

    Topics: Adrenal Glands; Alcohol Oxidoreductases; Aldosterone; Animals; Cattle; Corticosterone; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Metyrapone; Mitochondria; Mixed Function Oxygenases; NAD; NADP; Naphthalenes; Pyridines; Sheep

1966
Cytochrome P450 and steroid 11beta-hydroxylation in mitochondria from human adrenal cortex.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:8

    Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Antimycin A; Breast Neoplasms; Carbon Monoxide; Cushing Syndrome; Cytochromes; Electron Transport; Humans; Malates; Metyrapone; Mitochondria; Mixed Function Oxygenases; NAD; NADP; Spectrophotometry; Stereoisomerism; Stimulation, Chemical; Succinates

1968
Interaction of mixed function oxidase with its substrates and associated redox transitions of cytochrome P-450 and pyridine nucleotides in perfused rat liver.
    European journal of biochemistry, 1970, Volume: 15, Issue:3

    Topics: Animals; Cytochromes; Endoplasmic Reticulum; Fluorescence; Hexobarbital; Lactates; Liver; Male; Metyrapone; Microsomes, Liver; NAD; NADP; Oxidoreductases; Oxygen Consumption; Perfusion; Phenobarbital; Pyruvates; Rats; Spectrophotometry

1970
Ethanol and metyrapone effect on the redox potential, its compartimentalization, and its relation to the high energy phosphates of the rat liver in vivo.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196

    Topics: Animals; Ethanol; Hydroxybutyrate Dehydrogenase; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Ligases; Liver; Malate Dehydrogenase; Male; Metyrapone; NAD; NADP; Oxidation-Reduction; Oxidative Phosphorylation; Oxidoreductases; Pyruvates; Rats

1972
Stereochemical aspects of the metabolism of phenprocoumon in rat liver microsomes.
    Biochemical pharmacology, 1981, Jul-01, Volume: 30, Issue:13

    Topics: 4-Hydroxycoumarins; Animals; Biotransformation; Carbon Monoxide; Chemical Phenomena; Chemistry; Hydroxylation; In Vitro Techniques; Metyrapone; Microsomes, Liver; NAD; Phenprocoumon; Proadifen; Rats; Stereoisomerism

1981
Nuclear metabolism. I. Determination of styrene monooxygenase activity in rat liver nuclei.
    Chemico-biological interactions, 1980, Volume: 29, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; In Vitro Techniques; Liver; Male; Metyrapone; Microsomes, Liver; NAD; NADP; Nuclear Envelope; Phenobarbital; Rats; Styrenes

1980
Liver microsomal metabolism of N-methylcarbazole: a probe for induction, inhibition, and species differences.
    Molecular pharmacology, 1980, Volume: 17, Issue:1

    Topics: Animals; Benzoflavones; Carbazoles; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Phenobarbital; Proadifen; Rabbits; Rats; Species Specificity

1980
Biotransformation of all-trans-retinol and all-trans-retinal to all-trans-retinoic acid in rat conceptal homogenates.
    Biochemical pharmacology, 1995, Oct-12, Volume: 50, Issue:8

    Topics: Acyclic Monoterpenes; Animals; Biotransformation; Embryo, Mammalian; Embryonic and Fetal Development; Enzyme Inhibitors; Gestational Age; In Vitro Techniques; Metyrapone; Monoterpenes; NAD; NADP; Rats; Rats, Sprague-Dawley; Rats, Wistar; Retinaldehyde; Terpenes; Tretinoin; Vitamin A

1995
A soluble Bacillus cereus cytochrome P-450cin system catalyzes 1,4-cineole hydroxylations.
    Applied and environmental microbiology, 1993, Volume: 59, Issue:11

    Topics: Amines; Bacillus cereus; Cyclohexane Monoterpenes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexanes; Hydroxylation; Imidazoles; Metyrapone; Monoterpenes; NAD; Oxygen; Oxygenases; Proadifen; Solubility; Terpenes

1993
The purification and properties of a novel carbonyl reducing enzyme from mouse liver microsomes.
    Advances in experimental medicine and biology, 1993, Volume: 328

    Topics: Alcohol Oxidoreductases; Animals; Cytosol; Female; Guinea Pigs; Humans; In Vitro Techniques; Male; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Rats; Rats, Wistar; Species Specificity; Substrate Specificity

1993
Inhibition by SKF-525A of the aldehyde oxidase-mediated metabolism of the experimental antitumour agent acridine carboxamide.
    Biochemical pharmacology, 1993, May-25, Volume: 45, Issue:10

    Topics: Acridines; Acridones; Aldehyde Oxidase; Aldehyde Oxidoreductases; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cimetidine; Cytosol; Kinetics; Liver; Male; Methimazole; Metyrapone; Microsomes, Liver; NAD; Proadifen; Rats; Rats, Wistar

1993
The existence and significance of redox-cycling ubiquinone in lysosomes.
    Protoplasma, 2001, Volume: 217, Issue:1-3

    Topics: Animals; Cyclic N-Oxides; Cytochrome b Group; Electron Spin Resonance Spectroscopy; Electron Transport; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Liver; Lysosomes; Metyrapone; Mitochondria; Models, Biological; NAD; Oxidation-Reduction; Oxygen; Protons; Rats; Rotenone; Spin Labels; Ubiquinone; Uncoupling Agents

2001
[THE ADRENAL HISTO-ENZYMATIC PICTURE DURING PHARMACOLOGICAL BLOCKING OF 11-BETA-HYDROXYLATION IN RATS].
    Folia endocrinologica, 1963, Volume: 16

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Dihydrolipoamide Dehydrogenase; Glucosephosphate Dehydrogenase; Hydroxylation; Ketones; Metabolism; Metyrapone; Mineralocorticoid Receptor Antagonists; NAD; NADP; Pharmacology; Rats; Research

1963
Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells.
    Chemico-biological interactions, 2006, Aug-25, Volume: 162, Issue:2

    Topics: Benzoflavones; Breast Neoplasms; Catalase; Cell Line, Tumor; Cell Survival; Chelating Agents; Cytochrome P-450 Enzyme Inhibitors; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Fluoresceins; Humans; Metyrapone; Molecular Structure; NAD; NADP; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Biphenyls; Reactive Oxygen Species; Tamoxifen

2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
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