Page last updated: 2024-08-17

nad and methylnitronitrosoguanidine

nad has been researched along with methylnitronitrosoguanidine in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (44.44)	18.7374
1990's	14 (19.44)	18.2507
2000's	18 (25.00)	29.6817
2010's	8 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kinghorn, JR; Pateman, JA	1
Jacobson, MK; Juarez-Salinas, H; Sims, JL	1
Hansen, EJ; Juni, E	1
Chen, X; Dai, Y; Fang, M; Yu, Y	1
Ben-Hur, E; Elkind, MM; Shibuya, ML; Wells, RL	1
Bürkle, A; de Murcia, G; Küpper, JH	1
Kawada, J; Nishida, M; Nukatsuka, M; Yoshimura, Y	1
Cerutti, P; Krupitza, G	1
Berger, NA; Berger, SJ; Chatterjee, S; Hirschler, NV; Petzold, SJ	1
Ebel, JP; Gilson, G; Remy, P	1
Berger, NA; Berger, SJ	1
Chen, XR; Dai, YF; Yu, YN	1
Barankiewicz, J; Cohen, A	1
Campbell, PI; Kempson, SA	1
Alvarez-Gonzalez, R; Jacobson, MK	1
Berger, NA; Berger, SJ; Sudar, DC	1
Dritschilo, A; Kasid, UN; Lubet, RA; Smulson, ME; Stefanik, DF	1
Berger, NA; Das, SK	1
Benjamin, RC; Sims, JL	1
Berger, NA; Berger, SJ; Chatterjee, S; Petzold, SJ	1
Jacobson, EL; Jacobson, MK; Jonsson, GG	1
Jacobson, EL; Jacobson, MK; Jonsson, GG; Menard, L; Poirier, GG	1
Ibric, LL; Peterson, AR; Peterson, H	1
Althaus, FR; Alvarez-Gonzalez, R; Eichenberger, R	1
de Vries, GE; Harms, N; Maurer, K; Stouthamer, AH; Veltkamp, E	1
Schwartz, JL	1
Hoshino, J; Kröger, H; Studinger, G	1
Barton, RA; Jacobson, EL; Jacobson, MK; Juarez-Salinas, H; Levi, V	1
Berger, NA; Berger, SJ; Catino, DM; Sikorski, GW; Sims, JL	1
Berger, NA; Berger, SJ; Sims, JL	2
Jacobson, EL; Jacobson, MK; Mingmuang, M; Payne, DM; Smith, JY	1
Berger, NA; Berger, SJ; Catino, DM; Sims, JL	1
Busbee, DL; Jacobson, MK; Mitchell, VR; Rankin, PW	1
Jacobson, MK; McCurry, LS	1
Busbee, DL; Cantrell, ET; Jacobson, MK; Mitchell, VR; Rankin, P	1
Boorstein, RJ; Haldar, J; Poirier, G; Putnam, D	1
Althaus, FR; Kleczkowska, HE	2
Bürkle, A; Küpper, JH; Wolf, I	1
Boulton, S; Durkacz, BW; Kyle, S	1
Ogata, S; Okumura, K; Taguchi, H	1
Browning, JC; Davis, RE; Hsieh, JC; Katsikis, PD; Lu, QA; Mysore, V	1
Amé, JC; Jacobson, EL; Jacobson, MK; Koh, DW; Shieh, WM; Wang, ZQ; Wilson, MV	1
Affar, EB; Poirier, GG; Shah, RG	1
Küpper, JH; Müller, M; Wolf, I	1
Poirier, GG; Sallmann, FR; Satoh, MS; Vodenicharov, MD	1
Cheung, A; Huang, S; Lautar, S; Li, JH; Ramsey, C; Zhang, J	1
Affar, el B; Castonguay, V; Dallaire, AK; Shah, GM; Shah, RG	1
Bowers, WJ; Coombs, C; Dawson, TM; Dawson, VL; Federoff, HJ; Poirier, GG; Poitras, MF; Wang, H; Yu, SW	1
Alano, CC; Chen, Y; Swanson, RA; Ying, W	1
Garnier, P; Swanson, RA; Ying, W	1
Hasmann, M; Nüssler, V; Pelka-Fleischer, R; Pogrebniak, A; Schemainda, I	1
Swanson, RA; Ying, W; Zhu, K	1
Chi, NW; Lee, RM; Meyer, TN; Nguyen, MT; Sbodio, JI; Yeh, TY	1
Chiarugi, A; Cipriani, G; Fossati, S; Moroni, F	1
Azzam, K; Hasmann, M; Nüssler, V; Pelka-Fleischer, R; Pogrebniak, A; Schemainda, I	1
Coyle, DL; Gao, H; Jacobson, EL; Jacobson, MK; Meyer, RG; Meyer-Ficca, ML; Wang, ZQ	1
Hatano, T; Maruta, H; Okita, N; Takasawa, R; Tanuma, S; Uchiumi, F	1
Bast, A; Brauers, K; Geraets, L; Gottschalk, RW; Hageman, GJ; Moonen, HJ; Wouters, EF	1
Alano, CC; Karliner, JS; Swanson, RA; Tao, R; Tran, A; Ying, W	1
Bast, A; Brauers, K; Geraets, L; Hageman, GJ; Moonen, HJ; Wouters, EF	1
Giranda, VL; Liu, X; Luo, X; Luo, Y; Penning, T; Shi, Y; Zhu, GD	1
Rancourt, A; Satoh, MS	1
Alano, CC; Anderson, CM; Hunt, WT; Shao, Z; Suh, SW; Swanson, RA; Tang, KS	1
Beneke, S; Bürkle, A; Kunzmann, A; Schmitz, M; Weidele, K	1
Guo, HW; Wang, HW; Wei, YH	1
Arul, L; Ethier, C; Poirier, GG; Tardif, M	1
Higashi, Y; Nagasawa, K; Nishida, K; Okuda, H	1
Gan, L; Kauppinen, TM; Swanson, RA	1
Andrabi, SA; Chang, C; Dawson, TM; Dawson, VL; Gagné, JP; Karuppagounder, SS; Poirier, GG; Stevens, DA; Umanah, GK	1
Aghanoori, MR; Anderson, CM; Fernyhough, P; Hogan-Cann, AD; Kamboj, A; Lu, P; Roy Chowdhury, SK	1

Other Studies

72 other study(ies) available for nad and methylnitronitrosoguanidine

Article	Year
Mutants of Aspergillus nidulans lacking nicotinamide adenine dinucleotide-specific glutamate dehydrogenase. Journal of bacteriology, 1976, Volume: 125, Issue:1 Topics: Amino Acids; Ammonia; Aspergillus nidulans; Genes; Glutamate Dehydrogenase; Ketoglutaric Acids; Methylnitronitrosoguanidine; Mutagens; Mutation; NAD; Temperature	1976
Poly(ADP-ribose) levels in carcinogen-treated cells. Nature, 1979, Dec-13, Volume: 282, Issue:5740 Topics: Animals; Cell Line; Methylnitronitrosoguanidine; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Time Factors	1979
Isolation of mutants of Escherichia coli lacking NAD- and NADP-linked malic. Biochemical and biophysical research communications, 1975, Jul-22, Volume: 65, Issue:2 Topics: Cell-Free System; Escherichia coli; Genotype; Malate Dehydrogenase; Methylnitronitrosoguanidine; Mutation; NAD; NADP; Species Specificity; Time Factors; Transduction, Genetic	1975
ADPRT-mediated decrease of cellular NAD content and the detection of chemically induced DNA damage--development of a new short-term screening test for mutagens. Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 1990, Volume: 5, Issue:1 Topics: Amnion; Carcinogens; Cells, Cultured; DNA Damage; Humans; Methylnitronitrosoguanidine; Mutagenicity Tests; NAD; Poly(ADP-ribose) Polymerases	1990
Cellular NAD+ and ATP levels in alkylation-induced cytotoxicity enhanced by an inhibitor of poly(ADP-ribose) synthesis. Cancer biochemistry biophysics, 1990, Volume: 11, Issue:2 Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Survival; Cells, Cultured; Cricetinae; Fibroblasts; Intracellular Fluid; Kinetics; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors	1990
Inhibition of poly(ADP-ribosyl)ation by overexpressing the poly(ADP-ribose) polymerase DNA-binding domain in mammalian cells. The Journal of biological chemistry, 1990, Nov-05, Volume: 265, Issue:31 Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; DNA; Fibroblasts; Fluorescent Antibody Technique; Gene Library; Genetic Vectors; Humans; Methylnitronitrosoguanidine; NAD; Plasmids; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Transfection; Zinc Fingers	1990
Importance of the concentration of ATP in rat pancreatic beta cells in the mechanism of streptozotocin-induced cytotoxicity. The Journal of endocrinology, 1990, Volume: 127, Issue:1 Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cells, Cultured; Insulin; Islets of Langerhans; Methylnitronitrosoguanidine; Mitochondria, Liver; NAD; Oxygen Consumption; Rats; Rats, Inbred Strains; Streptozocin	1990
Poly(ADP-ribosylation) of histones in intact human keratinocytes. Biochemistry, 1989, May-02, Volume: 28, Issue:9 Topics: Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Epidermis; Histones; Humans; Keratins; Kinetics; Methylnitronitrosoguanidine; NAD; Nucleoside Diphosphate Sugars; Oxygen; Poly Adenosine Diphosphate Ribose	1989
Mutant cells defective in poly(ADP-ribose) synthesis due to stable alterations in enzyme activity or substrate availability. Experimental cell research, 1989, Volume: 184, Issue:1 Topics: Animals; Cell Line; Cricetinae; DNA Repair; In Vitro Techniques; Methylnitronitrosoguanidine; Molecular Weight; Mutation; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Proteins; Sister Chromatid Exchange	1989
Is Ap4A involved in DNA repair processes? Experimental cell research, 1988, Volume: 177, Issue:1 Topics: Adenine Nucleotides; Alkylation; Benzamides; Carcinoma, Hepatocellular; Dinucleoside Phosphates; DNA; DNA Repair; Hot Temperature; Kinetics; Liver Neoplasms; Methylnitronitrosoguanidine; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Biosynthesis; Tumor Cells, Cultured	1988
Metabolic consequences of DNA damage: the role of poly (ADP-ribose) polymerase as mediator of the suicide response. Basic life sciences, 1986, Volume: 38 Topics: Adenosine Triphosphate; Animals; Cell Survival; DNA Repair; Kinetics; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; Niacinamide; Poly(ADP-ribose) Polymerases	1986
The cell-cycle dependent and the DNA-damaging agent-induced changes of cellular NAD content and their significance. Mutation research, 1987, Volume: 191, Issue:1 Topics: 4-Nitroquinoline-1-oxide; Benzamides; Cell Cycle; Cell Line; DNA Damage; DNA Replication; Humans; Interphase; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases	1987
Metabolic consequences of DNA damage: alteration in purine metabolism following poly(ADP ribosyl)ation in human T-lymphoblasts. Archives of biochemistry and biophysics, 1987, Nov-01, Volume: 258, Issue:2 Topics: Adenine; Adenosine Triphosphate; Benzamides; Cell Line; Cell Survival; DNA Damage; Glycine; Humans; Methylnitronitrosoguanidine; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Purines; T-Lymphocytes	1987
Effect of carcinogenic nitroso compounds on rat kidney proximal tubule NAD levels. Progress in clinical and biological research, 1988, Volume: 258 Topics: Animals; Kidney Tubules, Proximal; Male; Methylnitronitrosoguanidine; Methylnitrosourea; Microvilli; NAD; Nitroso Compounds; Phosphates; Rats; Rats, Inbred Strains; Sodium; Streptozocin	1988
Characterization of polymers of adenosine diphosphate ribose generated in vitro and in vivo. Biochemistry, 1987, Jun-02, Volume: 26, Issue:11 Topics: Animals; Cell Membrane Permeability; Cell Transformation, Viral; Cells, Cultured; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Kinetics; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; NAD; Nucleoside Diphosphate Sugars; Phosphorus Radioisotopes; Poly Adenosine Diphosphate Ribose; Simian virus 40	1987
Metabolic consequences of DNA damage: DNA damage induces alterations in glucose metabolism by activation of poly (ADP-ribose) polymerase. Biochemical and biophysical research communications, 1986, Jan-14, Volume: 134, Issue:1 Topics: Adenosine Triphosphate; Animals; Cell Line; Enzyme Activation; Glucose; Glucose-6-Phosphate; Glucosephosphates; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; NADP; Poly(ADP-ribose) Polymerases	1986
Relationship between DNA strand breaks and inhibition of poly (ADP-ribosylation): enhancement of carcinogen-induced transformation. Carcinogenesis, 1986, Volume: 7, Issue:2 Topics: Animals; Base Sequence; Benzamides; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA, Neoplasm; Methylnitronitrosoguanidine; Mice; NAD; Oncogenes; Poly(ADP-ribose) Polymerase Inhibitors	1986
Alterations in deoxynucleoside triphosphate metabolism in DNA damaged cells: identification and consequences of poly(ADP-ribose) polymerase dependent and independent processes. Biochemical and biophysical research communications, 1986, Jun-30, Volume: 137, Issue:3 Topics: Animals; Benzamides; Cell Line; Deoxyribonucleotides; DNA; DNA Repair; Enzyme Activation; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases	1986
Alteration of poly(adenosine diphosphoribose) metabolism by ethanol: mechanism of action. Archives of biochemistry and biophysics, 1987, Volume: 253, Issue:2 Topics: Animals; Cattle; Cell Membrane Permeability; Cells, Cultured; Ethanol; Kinetics; Methylnitronitrosoguanidine; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Thymus Gland	1987
Strategy for selection of cell variants deficient in poly(ADP-ribose) polymerase. Experimental cell research, 1987, Volume: 172, Issue:2 Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Separation; Cell Survival; Cricetinae; Cricetulus; Enzyme Activation; Fibroblasts; Lung; Male; Methylnitronitrosoguanidine; NAD; Poly(ADP-ribose) Polymerases	1987
Mechanism of alteration of poly(adenosine diphosphate-ribose) metabolism by hyperthermia. Cancer research, 1988, Aug-01, Volume: 48, Issue:15 Topics: Adenosine Triphosphate; Animals; Benzamides; Fever; Glycoside Hydrolases; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose	1988
Effect of hyperthermia on poly(adenosine diphosphate-ribose) glycohydrolase. Cancer research, 1988, Aug-01, Volume: 48, Issue:15 Topics: Animals; Fever; Glycoside Hydrolases; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; NAD; Poly Adenosine Diphosphate Ribose	1988
Poly(ADP-ribose) synthesis and inhibition of DNA synthesis in Chinese hamster cells treated with methylating agents and thymidine. Mutation research, 1986, Volume: 161, Issue:2 Topics: Animals; Cricetinae; Cricetulus; Depression, Chemical; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Fibroblasts; Lung; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Thymidine	1986
Poly(ADP-ribose) biosynthesis and suicidal NAD+ depletion following carcinogen exposure of mammalian cells. Biochemical and biophysical research communications, 1986, Aug-14, Volume: 138, Issue:3 Topics: Animals; Benzamides; Carcinogens; Cell Line; Cells, Cultured; DNA Repair; Liver; Methylnitronitrosoguanidine; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Rats; Sulfuric Acid Esters; Ultraviolet Rays	1986
Isolation and characterization of Paracoccus denitrificans mutants with defects in the metabolism of one-carbon compounds. Journal of bacteriology, 1985, Volume: 164, Issue:3 Topics: Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Carbon; Cytochromes; Enzyme-Linked Immunosorbent Assay; Formate Dehydrogenases; Genes; Kinetics; Malate Dehydrogenase; Methanol; Methylnitronitrosoguanidine; Mutation; NAD; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans	1985
Potentiation of alkylation-induced sister chromatid exchange frequency by 3-aminobenzamide is mediated by intracellular loss of NAD+. Carcinogenesis, 1986, Volume: 7, Issue:1 Topics: Adenosine Triphosphate; Alkylation; Animals; Benzamides; Cell Line; Cell Membrane Permeability; Clone Cells; Cricetinae; Cricetulus; Drug Synergism; Female; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD; Ovary; Sister Chromatid Exchange	1986
Enhancement by streptozotocin and N-methyl-N'-nitro-N-nitrosoguanidine of the tyrosine aminotransferase activity in cultured rat liver cells: role of dexamethasone and NAD. Chemico-biological interactions, 1980, Volume: 32, Issue:3 Topics: Animals; Cells, Cultured; Dexamethasone; DNA; Enzyme Induction; Liver; Methylnitronitrosoguanidine; NAD; Niacinamide; Poly Adenosine Diphosphate Ribose; Rats; RNA; Streptozocin; Tyrosine Transaminase	1980
Effect of carcinogenic N-alkyl-N-nitroso compounds on nicotinamide adenine dinucleotide metabolism. Cancer research, 1980, Volume: 40, Issue:6 Topics: Animals; Carcinogens; DNA; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; NAD; NAD+ Nucleosidase; Nitrosourea Compounds; Poly(ADP-ribose) Polymerases; Streptozocin; Time Factors	1980
Poly(adenosinediphosphoribose) polymerase inhibitors stimulate unscheduled deoxyribonucleic acid synthesis in normal human lymphocytes. Biochemistry, 1982, Apr-13, Volume: 21, Issue:8 Topics: Benzamides; DNA; DNA Repair; Humans; Lymphocytes; Methylnitronitrosoguanidine; NAD; NAD+ Nucleosidase; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Purines; Pyrazinamide	1982
Poly(ADP-ribose) Polymerase inhibitors preserve nicotinamide adenine dinucleotide and adenosine 5'-triphosphate pools in DNA-damaged cells: mechanism of stimulation of unscheduled DNA synthesis. Biochemistry, 1983, Oct-25, Volume: 22, Issue:22 Topics: Adenosine Triphosphate; Animals; Benzamides; Cells, Cultured; DNA; DNA Repair; DNA, Neoplasm; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; NAD+ Nucleosidase; Neoplasm Proteins; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; RNA, Neoplasm	1983
Mono- and poly(ADP-ribose) metabolism following DNA damage. Princess Takamatsu symposia, 1983, Volume: 13 Topics: Adenosine Diphosphate Ribose; Benzamides; DNA; DNA Repair; Fibroblasts; Methylnitronitrosoguanidine; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Theophylline; Ultraviolet Rays	1983
Poly(ADP-ribose) polymerase mediates the suicide response to massive DNA damage: studies in normal and DNA-repair defective cells. Princess Takamatsu symposia, 1983, Volume: 13 Topics: Adenosine Triphosphate; Animals; DNA Repair; Humans; In Vitro Techniques; Leukemia L1210; Methylnitronitrosoguanidine; NAD; NAD+ Nucleosidase; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases	1983
Effects of nicotinamide on NAD and poly(ADP-ribose) metabolism in DNA-damaged human lymphocytes. Journal of supramolecular structure and cellular biochemistry, 1981, Volume: 16, Issue:3 Topics: DNA Repair; DNA Replication; Humans; Kinetics; Lymphocytes; Methylnitronitrosoguanidine; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose	1981
Reduction of nicotinamide adenine dinucleotide levels by ultimate carcinogens in human lymphocytes. Cancer research, 1980, Volume: 40, Issue:6 Topics: Carcinogens; DNA; DNA Repair; Humans; Lymphocytes; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD	1980
Poly(ADP-ribose) synthesis following DNA damage in cells heterozygous or homozygous for the xeroderma pigmentosum genotype. The Journal of biological chemistry, 1981, Jan-25, Volume: 256, Issue:2 Topics: Cell Line; DNA; DNA Repair; Fibroblasts; Heterozygote; Homozygote; Humans; Kinetics; Methylnitronitrosoguanidine; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Ultraviolet Rays; Xeroderma Pigmentosum	1981
Correlation of carcinogen-induced unscheduled DNA synthesis and NAD reduction in fresh human lymphocytes. Cancer letters, 1980, Volume: 11, Issue:2 Topics: Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Dimethyl Sulfoxide; DNA; Humans; Lymphocytes; Methylnitronitrosoguanidine; NAD; Theophylline; Thymidine	1980
DNA base excision repair of 5-hydroxymethyl-2'-deoxyuridine stimulates poly(ADP-ribose) synthesis in Chinese hamster cells. Carcinogenesis, 1995, Volume: 16, Issue:5 Topics: Animals; Antineoplastic Agents; Benzamides; Bromodeoxyuridine; Carcinogens; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA Repair; Kinetics; Methylnitronitrosoguanidine; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Thymidine; Time Factors	1995
Response of human keratinocytes to extremely low concentrations of N-methyl-N'-nitro-N-nitrosoguanidine. Mutation research, 1996, Mar-01, Volume: 367, Issue:3 Topics: Carcinogens; Cell Survival; Clone Cells; Cycloheximide; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Humans; Keratinocytes; Methylnitronitrosoguanidine; NAD; Poly Adenosine Diphosphate Ribose	1996
Biochemical changes associated with the adaptive response of human keratinocytes to N-methyl-N'-nitro-N-nitrosoguanidine. Mutation research, 1996, Jun-12, Volume: 368, Issue:2 Topics: Adaptation, Physiological; Cell Line; DNA Damage; Electrophoresis, Polyacrylamide Gel; Humans; Keratinocytes; Methylnitronitrosoguanidine; Mutagens; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Polymers; Time Factors	1996
NAD+ loading of mammalian cells by electrotransfection leads to increased poly(ADP-ribosyl)ation capacity. Biochimie, 1997, Volume: 79, Issue:4 Topics: Animals; Cell Line; Chlorocebus aethiops; Cricetinae; DNA Adducts; Electroporation; Fluorescent Antibody Technique; Methylnitronitrosoguanidine; NAD; Poly(ADP-ribose) Polymerases	1997
Low nicotinamide mononucleotide adenylyltransferase activity in a tiazofurin-resistant cell line: effects on NAD metabolism and DNA repair. British journal of cancer, 1997, Volume: 76, Issue:7 Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Division; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; Nicotinamide-Nucleotide Adenylyltransferase; Ribavirin; Temozolomide	1997
The effects of niacin on DNA repair after N-methyl-N'-nitro-N-nitrosoguanidine treatment in normal human lymphocytes. Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:12 Topics: Carcinogens; DNA; DNA Repair; Dose-Response Relationship, Drug; Humans; Methylnitronitrosoguanidine; NAD; Niacin; Niacinamide; Poly(ADP-ribose) Polymerases; T-Lymphocytes	1997
In situ staining for poly(ADP-ribose) polymerase activity using an NAD analogue. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1998, Volume: 46, Issue:11 Topics: Animals; Benzamides; Brain; Bromodeoxyuridine; Cell Line; Humans; Immunoenzyme Techniques; Methylnitronitrosoguanidine; Mice; NAD; Nitroprusside; Poly(ADP-ribose) Polymerases; Pyrogallol; Rats; Staining and Labeling; Ultraviolet Rays	1998
Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers. The Journal of biological chemistry, 1998, Nov-13, Volume: 273, Issue:46 Topics: 3T3 Cells; Animals; Chromatography, High Pressure Liquid; Genotype; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagens; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases	1998
Poly(ADP-ribose) turnover in quail myoblast cells: relation between the polymer level and its catabolism by glycohydrolase. Molecular and cellular biochemistry, 1999, Volume: 193, Issue:1-2 Topics: Animals; Cell Line; Coturnix; Dose-Response Relationship, Drug; Fibroblasts; Glycoside Hydrolases; Kinetics; Methylnitronitrosoguanidine; Mice; Muscles; Mutagens; NAD; Poly Adenosine Diphosphate Ribose; Time Factors	1999
NAD(+) consumption in carcinogen-treated hamster cells overexpressing a dominant negative mutant of poly(ADP-ribose) polymerase. Biochemical and biophysical research communications, 1999, Nov-19, Volume: 265, Issue:2 Topics: Animals; Carcinogens; Cell Line; Cricetinae; DNA; DNA Damage; Gamma Rays; Gene Expression; Methylnitronitrosoguanidine; Mutation; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Transfection	1999
Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1. Nucleic acids research, 2000, Oct-15, Volume: 28, Issue:20 Topics: Animals; Base Pair Mismatch; Cell Extracts; Cell Line; Cell-Free System; DNA Damage; DNA Methylation; DNA Repair; DNA, Single-Stranded; Dose-Response Relationship, Radiation; Fibroblasts; Gene Deletion; Kinetics; Methylnitronitrosoguanidine; Mice; Models, Genetic; Mutagens; NAD; Plasmids; Poly(ADP-ribose) Polymerases; Radiation Tolerance; X-Rays	2000
GPI 6150 prevents H(2)O(2) cytotoxicity by inhibiting poly(ADP-ribose) polymerase. Biochemical and biophysical research communications, 2000, Nov-30, Volume: 278, Issue:3 Topics: ADP Ribose Transferases; Animals; Benzopyrans; Cell Survival; DNA Damage; DNA Repair; Enzyme Inhibitors; Hydrogen Peroxide; Isoquinolines; Kinetics; Leukemia P388; Methylnitronitrosoguanidine; Mice; NAD; Plasmids; Poly(ADP-ribose) Polymerase Inhibitors; Transfection; Tumor Cells, Cultured	2000
Role of poly(ADP-ribose) polymerase in rapid intracellular acidification induced by alkylating DNA damage. Proceedings of the National Academy of Sciences of the United States of America, 2002, Jan-08, Volume: 99, Issue:1 Topics: Adenosine Triphosphate; Alkylating Agents; Apoptosis; Caspase 3; Caspases; Cell Death; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Immunoblotting; Jurkat Cells; Methylnitronitrosoguanidine; NAD; Necrosis; Poly(ADP-ribose) Polymerases; Time Factors; U937 Cells	2002
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science (New York, N.Y.), 2002, Jul-12, Volume: 297, Issue:5579 Topics: Active Transport, Cell Nucleus; Animals; Antibodies; Apoptosis; Apoptosis Inducing Factor; Caspase Inhibitors; Caspases; Cell Nucleus; Cells, Cultured; Cytochrome c Group; Enzyme Activation; Enzyme Inhibitors; Flavoproteins; Hydrogen Peroxide; Membrane Potentials; Membrane Proteins; Methylnitronitrosoguanidine; Mice; Mice, Knockout; Mitochondria; N-Methylaspartate; NAD; Neurons; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Receptors, N-Methyl-D-Aspartate	2002
Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2002, Volume: 22, Issue:7 Topics: Animals; Animals, Newborn; Astrocytes; Cell Death; Cells, Cultured; Citric Acid Cycle; Coculture Techniques; Enzyme Activation; Glycolysis; Ketoglutaric Acids; Methylnitronitrosoguanidine; Mice; NAD; Neurons; Poly(ADP-ribose) Polymerases; Pyruvic Acid	2002
NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes. Biochemical and biophysical research communications, 2003, Sep-05, Volume: 308, Issue:4 Topics: Animals; Astrocytes; Cell Death; Cell Survival; Cells, Cultured; Connexin 43; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Glycolysis; Methylnitronitrosoguanidine; Mice; Mice, Knockout; NAD; Poly(ADP-ribose) Polymerases	2003
Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects. European journal of medical research, 2003, Oct-22, Volume: 8, Issue:10 Topics: 1-Naphthylamine; Adenosine Triphosphate; Alkylating Agents; Apoptosis; Benzamides; Cell Death; Cell Line, Tumor; Cell Size; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia; Melphalan; Methylnitronitrosoguanidine; NAD; Naphthalimides; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones	2003
NADH can enter into astrocytes and block poly(ADP-ribose) polymerase-1-mediated astrocyte death. Neuroreport, 2005, Aug-01, Volume: 16, Issue:11 Topics: Animals; Animals, Newborn; Astrocytes; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Methylnitronitrosoguanidine; Mice; NAD; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases	2005
Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1. Molecular and cellular biochemistry, 2005, Volume: 276, Issue:1-2 Topics: Animals; Cell Death; Cell Line; Cytoprotection; Dogs; Enzyme Induction; Enzyme Inhibitors; Gene Expression; Homeostasis; Humans; Hydrogen Peroxide; Methylnitronitrosoguanidine; Mutagens; NAD; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tankyrases	2005
Neither energy collapse nor transcription underlie in vitro neurotoxicity of poly(ADP-ribose) polymerase hyper-activation. Neurochemistry international, 2007, Volume: 50, Issue:1 Topics: Adenosine Triphosphate; Animals; Caspases; Cell Death; Enzyme Activation; In Vitro Techniques; MAP Kinase Kinase 4; Methylnitronitrosoguanidine; Mice; NAD; Poly(ADP-ribose) Polymerases; Transcription, Genetic	2007
Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents. European journal of medical research, 2006, Aug-30, Volume: 11, Issue:8 Topics: Acrylamides; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cell Death; Cell Line, Tumor; Cell Survival; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Combinations; Humans; K562 Cells; Leukemia, Myeloid, Acute; Melphalan; Methylnitronitrosoguanidine; Monocytes; NAD; Piperidines	2006
Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase. Experimental cell research, 2007, Mar-10, Volume: 313, Issue:5 Topics: Animals; Cells, Cultured; DNA Breaks; DNA Damage; DNA-Binding Proteins; Enzyme Precursors; Glycoside Hydrolases; Histones; Methylnitronitrosoguanidine; Mice; Mutation; NAD; Phosphorylation; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Time Factors; X-ray Repair Cross Complementing Protein 1	2007
The involvement of ATP produced via (ADP-Ribose)n in the maintenance of DNA replication apparatus during DNA repair. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3 Topics: Adenosine Triphosphate; Benzamides; Cell Nucleus; Chromatography, High Pressure Liquid; Chromosomal Proteins, Non-Histone; Diphosphates; DNA Damage; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoside Hydrolases; HeLa Cells; Humans; Hydrolyzable Tannins; Methylnitronitrosoguanidine; Models, Biological; NAD; Poly Adenosine Diphosphate Ribose; S Phase; Thymidine Monophosphate	2007
Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression. European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3 Topics: Alcohol Oxidoreductases; Antioxidants; Benzamides; Cell Line, Tumor; Cell Nucleus; Cyclic N-Oxides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferrous Compounds; Flavones; Flavonoids; Gene Expression Regulation; Humans; Hydrogen Peroxide; Interleukin-8; Lipopolysaccharides; Methylnitronitrosoguanidine; Molecular Structure; NAD; NF-kappa B; Nucleotidases; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; Spin Trapping; Transcription, Genetic	2007
Differences among cell types in NAD(+) compartmentalization: a comparison of neurons, astrocytes, and cardiac myocytes. Journal of neuroscience research, 2007, Nov-15, Volume: 85, Issue:15 Topics: Animals; Astrocytes; Blotting, Western; Cell Death; Cells, Cultured; Cyclosporine; Cytosol; Enzyme Activation; Male; Methylnitronitrosoguanidine; Mice; Myocytes, Cardiac; NAD; Neurons; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley	2007
Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells. The Journal of nutrition, 2007, Volume: 137, Issue:10 Topics: Cell Line, Tumor; Diet; Flavones; Flavonols; Humans; Interleukin-8; Lung; Methylnitronitrosoguanidine; NAD; NF-kappa B; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Respiratory Mucosa	2007
Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damage. Cancer biology & therapy, 2008, Volume: 7, Issue:6 Topics: Alkylating Agents; Animals; Apoptosis; Benzimidazoles; Cytochromes c; DNA Damage; Fibroblasts; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Methylnitronitrosoguanidine; Mice; NAD; Oligomycins; Poly(ADP-ribose) Polymerases	2008
Delocalization of nucleolar poly(ADP-ribose) polymerase-1 to the nucleoplasm and its novel link to cellular sensitivity to DNA damage. DNA repair, 2009, Mar-01, Volume: 8, Issue:3 Topics: Adenosine Diphosphate Ribose; Apoptosis; Apoptosis Inducing Factor; Camptothecin; Cell Nucleus; DNA Damage; DNA Repair; DNA Topoisomerases, Type I; Enzyme Inhibitors; HeLa Cells; Humans; Methylnitronitrosoguanidine; NAD; Nuclear Proteins; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Topoisomerase I Inhibitors; Transcription, Genetic	2009
Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity. Glia, 2010, Volume: 58, Issue:4 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alkylating Agents; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Glutamic Acid; Methylnitronitrosoguanidine; Mice; Mice, Knockout; NAD; Neurons; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Time Factors	2010
Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells. Biochemical pharmacology, 2010, Oct-01, Volume: 80, Issue:7 Topics: Adenosine Diphosphate Ribose; Adult; Blood Cells; Cell Death; Cell Survival; Cells; DNA Damage; DNA Repair; Female; Humans; Male; Methylnitronitrosoguanidine; Middle Aged; NAD; Neutrophils; Niacin; Nicotinic Acids; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational	2010
Reduced nicotinamide adenine dinucleotide fluorescence lifetime detected poly(adenosine-5'-diphosphate-ribose) polymerase-1-mediated cell death and therapeutic effect of pyruvate. Journal of biomedical optics, 2011, Volume: 16, Issue:6 Topics: Adenosine Triphosphate; Cell Death; Cell Survival; Glucose; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Methylnitronitrosoguanidine; Microscopy, Fluorescence; NAD; Oxygen Consumption; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Pyruvic Acid	2011
PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent. PloS one, 2012, Volume: 7, Issue:10 Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alkylating Agents; AMP-Activated Protein Kinases; Autophagy; Blotting, Western; Enzyme Activation; HEK293 Cells; HeLa Cells; Humans; Methylnitronitrosoguanidine; Microtubule-Associated Proteins; Models, Biological; NAD; Necrosis; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; RNA Interference; Signal Transduction; TOR Serine-Threonine Kinases	2012
NAD(+) influx through connexin hemichannels prevents poly(ADP-ribose) polymerase-mediated astrocyte death. Life sciences, 2013, Apr-19, Volume: 92, Issue:13 Topics: Adenosine; Animals; Astrocytes; Biological Transport; Cell Death; Cell Survival; Cells, Cultured; Connexins; Methylnitronitrosoguanidine; Mice; NAD; Niacinamide; Poly(ADP-ribose) Polymerases; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7	2013
Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation. Biochimica et biophysica acta, 2013, Volume: 1833, Issue:8 Topics: Acetylation; Animals; Astrocytes; Carbazoles; Cells, Cultured; eIF-2 Kinase; Humans; Methylnitronitrosoguanidine; Mice; NAD; NF-kappa B; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Sirtuin 1; Transcription, Genetic; Transcriptional Activation; Transfection	2013
Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis. Proceedings of the National Academy of Sciences of the United States of America, 2014, Jul-15, Volume: 111, Issue:28 Topics: Acrylamides; Animals; Cells, Cultured; Cerebral Cortex; Enzyme Activation; Glucose; Glucose-6-Phosphate; Glycolysis; Hexokinase; Methylnitronitrosoguanidine; Mice; Mitochondria; NAD; Nerve Tissue Proteins; Neurons; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases	2014
Poly(ADP-ribose) polymerase-1 inhibits mitochondrial respiration by suppressing PGC-1α activity in neurons. Neuropharmacology, 2019, 12-01, Volume: 160 Topics: Acetylation; Animals; Cell Respiration; DNA-Binding Proteins; DNA, Mitochondrial; High Mobility Group Proteins; Methylnitronitrosoguanidine; Mice; Mitochondria; NAD; Neurons; Nuclear Respiratory Factor 1; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Poly (ADP-Ribose) Polymerase-1; Sirtuin 1; Transcription Factors; Transcription, Genetic	2019