nad has been researched along with methotrexate in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (79.49) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 4 (10.26) | 29.6817 |
| 2010's | 2 (5.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chauvin, MM; Chippel, D; Korri, KK; Scrimgeour, KG; Tirpak, A | 1 |
| Kaufman, BT; Subramanian, S | 1 |
| Gazzoli, M; Roberts, J; Smulson, M; Stark, P | 1 |
| Krumdieck, CL; White, WE; Yielding, LK | 1 |
| Kaufman, S; Pollock, RJ | 1 |
| Greenfield, NJ | 1 |
| Campello, AP; Klüppel, ML; Lopes, LC; Yamamoto, N | 1 |
| Malec, J; Przybyszewski, WM | 1 |
| Gaal, JC; Pearson, CK; Prise, KM | 1 |
| Armarego, WL; Shaw, DC; Vasudevan, SG | 1 |
| Salord, J; Schuber, F | 1 |
| Cotton, DW; van Rossum, E | 1 |
| Greenfield, NJ; Poe, M; Williams, MN | 1 |
| Schaefer, H; Schalla, W; Zesch, A | 1 |
| Gawthorne, JM; Smith, RM | 1 |
| Witthaus, G | 1 |
| Gutteridge, WE; Jaffe, JJ; McCormack, JJ | 1 |
| Jaffe, JJ; McCormack, JJ | 1 |
| Neal, GE; Stanley, BG; Williams, DC | 1 |
| Burchall, JJ; Hitchings, GH | 1 |
| Crosby, LK; Kozloff, LM; Lute, M; Verses, C | 1 |
| Bertino, JR; Cashmore, AR; Hillcoat, BL | 1 |
| Greenfield, NJ; Hirshfield, JM; Hoogsteen, K; Poe, M; Williams, MN | 1 |
| Anderson, LA; Goldman, ID; Matherly, LH | 1 |
| Bertino, JR; Kamen, BA; Whyte-Bauer, W | 1 |
| Hirayama, K; Katoh, S; Nakanisi, N; Sueoka, T; Yamada, S | 1 |
| Artymiuk, PJ; Poirrette, AR; Rice, DW; Willett, P | 1 |
| Lorber, DM; Shoichet, BK | 1 |
| Courteau, J; Kocsis-Bédard, S; Niyonsenga, T; Paquette, B; Thibodeau, PA | 1 |
| WILLIAMS, DC | 1 |
| KENNEDY, EP; LINDBERG, M; TIETZ, A | 1 |
| BERTINO, JR; JOHNS, DG; PERKINS, JP | 1 |
| MAINWARING, WI; WILLIAMS, DC | 1 |
| LAMBE, RF; WILLIAMS, DC | 1 |
| Ainavarapu, SR; Badilla, CL; Fernandez, JM; Li, L | 1 |
| Ainavarapu, SR; Fernandez, JM; Li, L | 1 |
| Carey, M; Hockenberry, M; Kaemingk, K; Krull, K; Miketova, P; Moore, IM; Pasvogel, A | 1 |
| Bobrovnikova-Marjon, E; Hurov, JB | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
2 review(s) available for nad and methotrexate
| Article | Year |
|---|---|
Inhibition of folate biosynthesis and function as a basis for chemotherapy.
Topics: Aminobenzoates; Animals; Binding Sites; Biological Transport; Drug Resistance, Microbial; Drug Synergism; Escherichia coli; Folic Acid; Folic Acid Antagonists; Glutamates; Guinea Pigs; Humans; Lactobacillus; Leucovorin; Methotrexate; NAD; NADP; Pteridines; Pyrimidines; Rabbits; Rats; Sulfonamides | 1965 |
Targeting metabolic changes in cancer: novel therapeutic approaches.
Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; DNA-Binding Proteins; Fatty Acids; Glutamine; Humans; Isocitrate Dehydrogenase; Methotrexate; NAD; Neoplasms; Phosphopyruvate Hydratase; Signal Transduction; Tumor Suppressor Proteins | 2014 |
37 other study(ies) available for nad and methotrexate
| Article | Year |
|---|---|
Quinonoid dihydropterin reductase from beef liver.
Topics: Adenosine Monophosphate; Amino Acids; Animals; Carboxypeptidases; Cattle; Chromatography, Affinity; Dihydropteridine Reductase; Hydrogen-Ion Concentration; Kinetics; Liver; Methotrexate; Molecular Weight; NAD; NADH, NADPH Oxidoreductases; Sheep | 1977 |
Interaction of methotrexate, folates, and pyridine nucleotides with dihydrofolate reductase: calorimetric and spectroscopic binding studies.
Topics: Animals; Calorimetry; Chickens; Folic Acid; Liver; Methotrexate; NAD; NADP; Protein Binding; Protons; Spectrum Analysis; Tetrahydrofolate Dehydrogenase; Thermodynamics | 1978 |
Release of template restriction for DNA synthesis by poly ADP(ribose) polymerase during the HeLa cell cycle.
Topics: Adenosine Diphosphate; Cell Division; Cell Nucleus; Cell-Free System; Cytoplasm; DNA Nucleotidyltransferases; DNA, Neoplasm; Escherichia coli; HeLa Cells; Humans; Methotrexate; NAD; Neoplasm Proteins; Nucleoproteins; Polynucleotides; Ribose; Streptozocin; Templates, Genetic; Thymine Nucleotides | 1975 |
Folates as inhibitors of glutamate dehydrogenase.
Topics: Aminobenzoates; Animals; Binding Sites; Cattle; Folic Acid; Glutamate Dehydrogenase; Glutamates; Kinetics; Liver; Methotrexate; NAD; Peptides; Pterins; Tetrahydrofolates | 1976 |
Dihydropteridine reductase may function in tetrahydrofolate metabolism.
Topics: Animals; Biopsy; Brain; Child; Child, Preschool; Dihydropteridine Reductase; Female; Glycine Hydroxymethyltransferase; Humans; Male; Mercaptoethanol; Methotrexate; NAD; NADH, NADPH Oxidoreductases; Phenylketonurias; Rats; Tetrahydrofolates; Transferases | 1978 |
Circular dichroism studies of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli B, MB 1428: ternary complexes.
Topics: Adenosine Diphosphate Sugars; Binding Sites; Circular Dichroism; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Methotrexate; NAD; NADP; Nicotinamide Mononucleotide; Protein Binding; Protein Conformation; Ribose; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase | 1975 |
Methotrexate: studies on cellular metabolism. II--Effects on mitochondrial oxidative metabolism and ion transport.
Topics: Animals; Glutamate Dehydrogenase; Glycerolphosphate Dehydrogenase; In Vitro Techniques; Ions; Isocitrate Dehydrogenase; Ketoglutarate Dehydrogenase Complex; Malate Dehydrogenase; Male; Membrane Potentials; Methotrexate; Mitochondria, Liver; Mitochondrial Swelling; NAD; Oxidation-Reduction; Rats; Succinate Dehydrogenase | 1989 |
Hydroxyurea, methotrexate and adriblastine can mediate non-enzymatic reduction of nitroblue tetrazolium with NADH which is inhibited by superoxide dismutase.
Topics: Antibiotics, Antineoplastic; Doxorubicin; Free Radicals; Hydroxyurea; Methotrexate; NAD; Nitroblue Tetrazolium; Oxidation-Reduction; Superoxide Dismutase; Superoxides; Tetrazolium Salts | 1987 |
Increased protein ADPribosylation in HeLa cells exposed to the anti-cancer drug methotrexate.
Topics: Adenosine Diphosphate Ribose; Cell Nucleus; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Kinetics; Methotrexate; Molecular Weight; NAD; Neoplasm Proteins; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases | 1986 |
Dihydropteridine reductase from Escherichia coli.
Topics: Amino Acid Sequence; Chromatography, Ion Exchange; Dihydropteridine Reductase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flavin-Adenine Dinucleotide; Kinetics; Methotrexate; Molecular Sequence Data; Molecular Weight; NAD; NADH, NADPH Oxidoreductases; Spectrophotometry, Ultraviolet; Substrate Specificity | 1988 |
In vitro drug delivery mediated by ecto-NAD+-glycohydrolase ligand-targeted liposomes.
Topics: Ammonium Chloride; Animals; Antineoplastic Agents; Burkitt Lymphoma; Cell Division; Cell Line; Deoxyuridine; Drug Carriers; Fibroblasts; Humans; Kinetics; Liposomes; Methotrexate; Mice; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Sulfhydryl Compounds; Tumor Cells, Cultured | 1988 |
Glucose-6-phosphate dehydrogenase in the blood of psoriatics, and the effects of methotrexate.
Topics: Dermatitis, Atopic; Enzyme Repression; Female; Glucosephosphate Dehydrogenase; Humans; Male; Methotrexate; Mycosis Fungoides; NAD; NADP; Psoriasis; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
Dihydrofolate reductase from a methotrexate-resistant Escherichia coli.
Topics: Binding Sites; Drug Resistance, Microbial; Escherichia coli; Hydrogen-Ion Concentration; Methotrexate; NAD; NADP; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Ultrafiltration | 1974 |
The estimation of enzyme activity in living epidermal cells.
Topics: Animals; Aspartate Aminotransferases; Chemistry Techniques, Analytical; Cytoplasm; Epithelial Cells; Epithelium; Forearm; Glycolysis; Guinea Pigs; Humans; In Vitro Techniques; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Malates; Methotrexate; Mitochondria; NAD; NADP; Ouabain; Oxygen; Prednisolone; Psoriasis; Pyruvate Kinase; Skin; Spectrophotometry | 1974 |
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on methotrexate transport and the activity of enzymes associated with folate metabolism in liver.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Female; Folic Acid; Homocysteine; Liver; Membranes; Methionine; Methotrexate; Methyltransferases; NAD; NADP; S-Adenosylmethionine; Serum Albumin, Bovine; Sheep; Tetrahydrofolate Dehydrogenase; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
[On the influence of methotrexate on the nucleotide content of the mastocytoma P-815].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Chromatography, Ion Exchange; Culture Techniques; Cytosine Nucleotides; Guanine Nucleotides; Mast Cells; Methotrexate; NAD; Neoplasms, Experimental; Nucleotides; Uracil Nucleotides | 1966 |
Presence and properties of dihydrofolate reductases within the genus Trypanosoma.
Topics: Aminopterin; Animals; Depression, Chemical; Folic Acid; Methotrexate; NAD; Tetrahydrofolate Dehydrogenase; Trypanosoma | 1968 |
Dihydrofolate reductase from Trypanosoma equiperdum. I. Isolation, partial purification, and properties.
Topics: Aminopterin; Animals; Folic Acid; Folic Acid Antagonists; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Methotrexate; NAD; NADP; Pyrimethamine; Rats; Tetrahydrofolate Dehydrogenase; Trypanosoma | 1967 |
The presence of a substance with hydrogen transporting properties in some samples of methotrexate.
Topics: Benzoates; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Drug Contamination; Drug Storage; Freeze Drying; Hydrogen; Methotrexate; Mitosis; NAD; NADP; Oxidation-Reduction; Tetrazolium Salts | 1968 |
Bacteriophage tail components. II. Dihydrofolate reductase in T4D bacteriophage.
Topics: Aminopterin; Animals; Binding Sites; Coliphages; Escherichia coli; Fluorometry; Folic Acid Antagonists; Formamides; Genes; Genetic Complementation Test; Genetics, Microbial; Immune Sera; Methotrexate; Mutation; NAD; NADP; Rabbits; Solvents; Spectrophotometry; Tetrahydrofolate Dehydrogenase; Urea; Viral Proteins; Virus Replication | 1970 |
"Induction" of dihydrofolate reductase: purification and properties of the "induced" human erythrocyte and leukocyte enzyme and normal bone marrow enzyme.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromatography; Enzyme Activation; Enzyme Induction; Erythrocytes; Folic Acid; Humans; Hydrogen-Ion Concentration; Immune Sera; Leukemia L1210; Leukocytes; Methotrexate; Molecular Weight; NAD; NADP; Neoplasms; Protein Denaturation; Tetrahydrofolate Dehydrogenase | 1970 |
Dihydrofolate reductase. Purification and characterization of the enzyme from an amethopterin-resistant mutant of Escherichia coli.
Topics: Amino Acids; Chromatography, Affinity; Chromatography, Gel; Cyanogen Bromide; Dansyl Compounds; Drug Resistance, Microbial; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Methotrexate; NAD; NADP; Osmolar Concentration; Potassium Chloride; Sodium Chloride; Tetrahydrofolate Dehydrogenase; Ultracentrifugation | 1972 |
Role of the cellular oxidation-reduction state in methotrexate binding to dihydrofolate reductase and dissociation induced by reduced folates.
Topics: Animals; Azides; Carcinoma, Ehrlich Tumor; Folic Acid Antagonists; Glucose; Indicators and Reagents; Kinetics; Leucovorin; Methotrexate; Mice; NAD; NADP; Oxidation-Reduction; Potassium Cyanide; Protein Binding; Rotenone; Sodium Azide; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 1984 |
A mechanism of resistance to methotrexate. NADPH but not NADH stimulation of methotrexate binding to dihydrofolate reductase.
Topics: Animals; Drug Resistance; Kinetics; Leukemia L1210; Methotrexate; Mice; NAD; NADP; Protein Binding; Tetrahydrofolate Dehydrogenase | 1983 |
Dihydropteridine reductase and tetrahydropterin in Crithidia fasciculata cells.
Topics: Aminopterin; Animals; Crithidia; Dihydropteridine Reductase; Methotrexate; Molecular Weight; NAD; NADH, NADPH Oxidoreductases; Pterins; Substrate Specificity | 1980 |
Comparison of protein surfaces using a genetic algorithm.
Topics: Alcohol Dehydrogenase; Algorithms; Antigen-Antibody Complex; Binding Sites; Enzyme Inhibitors; Heme; HIV Protease; HIV Protease Inhibitors; Ligands; Methotrexate; Models, Biological; Models, Molecular; Muramidase; Myoglobin; NAD; Neuraminidase; Pancreatic Elastase; Proteins; Rotation; Sialic Acids; Solvents; Surface Properties; Tetrahydrofolate Dehydrogenase | 1997 |
Flexible ligand docking using conformational ensembles.
Topics: Algorithms; Binding Sites; Computer Simulation; Crystallography, X-Ray; Databases as Topic; Deoxyuracil Nucleotides; Drug Design; Ligands; Methotrexate; Models, Molecular; Molecular Conformation; Molecular Structure; NAD; Protein Binding; Proteins; Software | 1998 |
Thiols can either enhance or suppress DNA damage induction by catecholestrogens.
Topics: Acetylcysteine; Antioxidants; Copper; Dithiothreitol; DNA Damage; Drug Resistance, Neoplasm; Estradiol; Estrogens, Catechol; Glutathione; Hydrogen Peroxide; Kinetics; Methotrexate; NAD; Oxidation-Reduction; Reactive Oxygen Species; Sulfhydryl Compounds; Thioctic Acid | 2001 |
THE RELATIONSHIP BETWEEN 3 ALPHA-HYDROXYSTEROID NICOTINAMIDE NUCLEOTIDE COENZYME TRANSHYDROGENATION AND BETA-GLUCURONIDASE IN REGENERATING RAT LIVER.
Topics: Androsterone; Coenzymes; Dialysis; Glucuronates; Glucuronidase; Heparin; Hepatectomy; Hydroxysteroids; Lactones; Liver; Liver Extracts; Liver Regeneration; Mercaptopurine; Methotrexate; NAD; NADP; Niacin; Niacinamide; Nucleotides; Oxidoreductases; Perfusion; Pharmacology; Rats; Renal Dialysis; Research; Spectrophotometry | 1964 |
A NEW PTERIDINE-REQUIRING ENZYME SYSTEM FOR THE OXIDATION OF GLYCERYL ETHERS.
Topics: Alcohols; Aldehydes; Chromatography; Ethers; Fatty Acids; Folic Acid; Glycerol; Glyceryl Ethers; Liver; Methotrexate; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Pteridines; Pterins; Rats; Research; Stearic Acids | 1964 |
PURIFICATION AND PROPERTIES OF DIHYDROFOLATE REDUCTASE FROM EHRLICH ASCITES CARCINOMA CELLS.
Topics: Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Chromatography; Enzyme Inhibitors; Kinetics; Methotrexate; NAD; Oxidoreductases; Research; Spectrophotometry; Tetrahydrofolate Dehydrogenase | 1965 |
THE INHIBITION OF TWO STEROID-ACTIVATED NICOTINAMIDE-ADENINE DINUCLEOTIDE (PHOSPHATE) TRANSHYDROGENASES BY FOLIC ACID AND FOLIC ACID ANTIMETABOLITES.
Topics: Aminopterin; Androsterone; Antimetabolites; Enzyme Inhibitors; Estradiol; Folic Acid; Hydrogen-Ion Concentration; Methotrexate; NAD; NADP; Oxidoreductases; Pharmacology; Phosphates; Progesterone; Research; Spectrophotometry; Testosterone | 1965 |
THE INHIBITION OF NICOTINAMIDE-ADENINE DINUCLEOTIDE-LINKED 3-ALPHA-HYDROXY STEROID DEHYDROGENASE BY CERTAIN ANTIMETABOLIC DRUGS.
Topics: Aminopterin; Antimetabolites; Diethylstilbestrol; Enzyme Inhibitors; Estradiol; Folic Acid; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Mercaptopurine; Methotrexate; NAD; Oxidoreductases; Research; Steroids; Testosterone; Uracil | 1965 |
Ligand binding modulates the mechanical stability of dihydrofolate reductase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biophysical Phenomena; Biophysics; CHO Cells; Chromatography, Affinity; Cricetinae; Folic Acid; Folic Acid Antagonists; Humans; Ligands; Methotrexate; Microscopy, Atomic Force; NAD; NADP; Niacinamide; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Protein Transport; Spectrophotometry; Stress, Mechanical; Tensile Strength; Tetrahydrofolate Dehydrogenase; Thermodynamics | 2005 |
Fingerprinting DHFR in single-molecule AFM studies.
Topics: Animals; Biophysical Phenomena; Biophysics; CHO Cells; Chromatography, Affinity; Cricetinae; Cricetulus; Folic Acid; Folic Acid Antagonists; Humans; Ligands; Methotrexate; Microscopy, Atomic Force; NAD; NADP; Niacinamide; Peptide Mapping; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Protein Transport; Spectrophotometry; Stress, Mechanical; Tensile Strength; Tetrahydrofolate Dehydrogenase; Thermodynamics | 2006 |
Methotrexate-induced alterations in beta-oxidation correlate with cognitive abilities in children with acute lymphoblastic leukemia.
Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Child; Chromatography, Gas; Cognition Disorders; Female; Humans; Intelligence Tests; Male; Methotrexate; NAD; Oxidation-Reduction; Palmitic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Performance; Risk Factors; Statistics, Nonparametric; Stearic Acids | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |