Page last updated: 2024-08-17

nad and malic acid

nad has been researched along with malic acid in 193 studies

Research

Studies (193)

TimeframeStudies, this research(%)All Research%
pre-199065 (33.68)18.7374
1990's38 (19.69)18.2507
2000's38 (19.69)29.6817
2010's41 (21.24)24.3611
2020's11 (5.70)2.80

Authors

AuthorsStudies
Matsuno, T2
Chagoya de Sánchez, V; Díaz-Muñoz, M; Hernández-Muñoz, R2
Caucheteux, D; Hombroeckx, A; Hue, L; Pouleur, H; Veitch, K1
Hirai, K; Ikeda, K; Wang, GY1
Berry, MN; Grivell, AR; Phillips, JW1
Berry, MN; Gregory, RB; Grivell, AR; Phillips, JW; Wallace, PG1
Cortés, A; Dordal, A; Gelpí, JL; Mazo, A; Montserrat, J1
Mansini, E; Oestreicher, EG; Ribeiro, LP1
Guidoux, R1
Ludden, PW; Lueddecke, BA; Woehle, DL1
Cleland, WW; Cook, PF; Gavva, SR; Harris, BG; Urbauer, JL; Weiss, PM1
Arnaud, A; Chagnaud, P; Galzy, P; Naouri, P1
Handler, JA; Kizaki, Z; Sugano, T; Thurman, RG; Yoshihara, H1
Ferrier, B1
Hall, PF; Kobayashi, Y; Yanagibashi, K1
Atlante, A; Passarella, S; Quagliariello, E1
Doi, S; Kobayashi, K; Negoro, S; Okada, H; Urabe, I1
Carlsen, BD; Lambeth, DO; Ray, PD1
Heikkila, RE; Nicklas, WJ; Vyas, I2
Ramsay, RR; Salach, JI; Singer, TP1
Bravo, C; Chávez, E; Jay, D1
Balaban, RS; Koretsky, AP1
Freter, M; Nyquist-Battie, C1
Baydoun, AR; Markham, A; Morgan, RM; Sweetman, AJ1
Berdanier, CD; Deaver, OE; McCusker, RH; Wander, RC1
Márquez, FJ; Medina, MA; Núñez de Castro, I; Pérez-Rodríguez, J; Quesada, AR; Sánchez-Jiménez, F1
Aberhart, DJ; Burns, DH1
Hassan, MN; Thakar, JH1
Agostino, A; Burnell, JN; Hatch, MD1
Batke, J; Ovadi, J; Srere, PA; Tompa, P; Welch, GR1
Kauppinen, RA; Nicholls, DG; Sihra, TS1
Hämäläinen, MM1
Aleksandrowicz, Z; Swierczyński, J; Zelewski, L1
Tomasiak, M1
Curi, R; Newsholme, EA; Newsholme, P1
Kostin, VI1
Klimek, J; Swierczyński, J; Zelewski, L2
Chua, BH; Kleinhans, BJ1
Adamson, I; Nylen, EG; Pande, SV; Wrogemann, K1
Giacomelli, F; Kuo, TH; Wiener, J1
Cook, PF; Harris, BG; Rao, JG1
Datta, A; Merz, JM; Spivey, HO1
Ashour, B; Hansford, RG1
Bird, MI; Lord, LA; Nunn, PB1
Grover, SD; Wedding, RT1
Cook, PF; Harris, BG; Kiick, DM; Park, SH1
Allen, BL; Cook, PF; Harris, BG; Kiick, DM; Rao, JG1
Smith, K; Sundaram, TK1
Charyulu, KK; Hirschberg, JG; Kohen, C; Kohen, E; Thorell, B; Westerhoff, HV; Wouters, AW1
Kohen, C; Kohen, E1
Aleksandrowicz, Z; Scisłowski, PW; Skorkowski, EF; Swierczyński, J1
Ward, PF1
Møller, IM; Palmer, JM; Schwitzguébel, JP1
Caspritz, G; Radler, F1
McKeehan, KA; McKeehan, WL1
Fagan, JM; Tischler, ME1
Brindle, KM; Campbell, ID; Simpson, RJ1
DeLuca, M; Wienhausen, G1
Giersch, C1
Baró, J; Bozal Fés, J; Cortés, A1
Koppenhafer, SL; Scholz, TD1
Raj, RK; Unnikrishnan, LS1
Catelloni, F; Fontaine, E; Keriel, C; Leverve, XM; Rigoulet, M; Sibille, B1
Burlakova, EB; Kaplan, EIa; Khristianovich, DS; Pakhomov, VIu; Rozantseva, TV; Voronkov, MG; Zhigacheva, IV1
Scaduto, RC1
Beattie, DS; Kiaira, JK; Obungu, VH1
Blanco, A; Burgos, C; Gallina, F; Gerez de Burgos, NM1
Alter, GM; Zimmerle, CT1
Davis, EJ; Dietzen, DJ1
Day, DA; Millar, AH; Whelan, J; Wiskich, JT1
Fischer, Y; Ionescu, AA; Jüngling, E; Kammermeier, H; Löken, C; Mertens, M; Timmerman, M1
Cook, PF; Peisach, J; Quinn, TP; Tipton, PA1
Anderson, BM; Anderson, CD; Wise, DJ1
Ashton, AR1
Atlante, A; Gagliardi, S; Passarella, S1
Koppenhafer, SL; Scholz, TD; Schutte, BC; tenEyck, CJ1
Srivastava, VM; Wani, JH1
Bonilla, AC; del Arenal Mena, IP; Escamilla, JE; Moreno-Sánchez, R1
Fischer, Y; Jüngling, E; Kammermeier, H1
Barron, JT; Gu, L; Parrillo, JE1
Kaleysa Raj, R; Sivan, VM1
Cook, PF; Hwang, CC; Karsten, WE1
Atlante, A; Calissano, P; Gagliardi, S; Marra, E; Passarella, S1
Rupert, BE; Scholz, TD; Schutte, BC; Segar, JL1
Edwards, JS; McCulloch, A; Palsson, BO; Ramakrishna, R1
Boyd, C; Cousins, K; Daya, S; Heron, P1
Alter, GM; Tung, PP1
Blasco, R; Castillo, F; Martínez-Luque, M1
Arai, T; Kamata, S; Sako, T; Takahashi, M1
Aitken, RJ; Fulton, N; Vernet, P; Wallace, C1
Reynolds, IJ; Votyakova, TV1
Arai, T; Azakami, D; Ikeda, M; Takahashi, M; Washizu, T1
Beattie, DS; Fang, J2
Cook, PF; Karsten, WE; Tipton, PA1
Geigenberger, P; Pfister, M; Schurr, U; van Dongen, JT1
BURTON, K; WILSON, TH1
HOLZER, H; SOELING, HD1
FURUYA, A; HAYASHI, JA1
ARNAUD, M; NORDMANN, J; NORDMANN, R1
BURTON, SD; MORITA, RY1
TAGER, JM1
FRANCIS, MJ; HUGHES, DE; KORNBERG, HL; PHIZACKERLEY, PJ1
ABELIOVITZ, A; BENZIMAN, M1
ORMSBEE, RA; PEACOCK, MG1
BEST, AN; PAYNE, WJ1
HENLEY, KS; LAUGHREY, EG1
MEHROTRA, KN; NATH, K; SHUKLA, KL1
BALAZS, R1
FRANCAVILLA, A; PALMIERI, F; PAPA, S; QUAGLIARIELLO, E; SACCONE, C1
BREMER, J; ELDJARN, L; SKREDE, S1
LUSHNIKOV, EF1
Feldkamp, T; Kemner, S; Kribben, A; Nissim, I; Roeser, NF; Senter, RA; Venkatachalam, MA; Weinberg, JM1
Di Pede, S; Passarella, S; Pastore, D1
Johansson, FI; Michalecka, AM; Møller, IM; Rasmusson, AG1
Chang, GG; Hsu, WC; Hung, HC; Tong, L1
Halliwell, B; Vincent, AS; Wong, KP; Zhang, X1
Bardonová, L; Dolezal, P; Embley, TM; Foster, PG; Hirt, RP; Hrdy, I; Tachezy, J1
Katunuma, N; Ohshima, T; Sakuraba, H; Tsuge, H; Yoneda, K1
Cabrera, ME; Saidel, GM; Stanley, WC; Yu, X; Zhou, L1
Andersen, PE; Flyvbjerg, H; Grigiene, J; Hagedorn, PH; Kasimova, MR; Krab, K; Møller, IM1
Aymerich, S; Doan, T; Lerondel, G; Sauer, U; Zamboni, N1
Björklund, A; Grill, V; Kotaleski, JH; Lansner, A; Westermark, PO1
Bender, K; Brennan, L; Maechler, P; Newsholme, P1
Alberty, RA1
Contreras, L; Gomez-Puertas, P; Iijima, M; Kobayashi, K; Saheki, T; Satrústegui, J1
Holden, JF; Hu, Y; Yennaco, LJ1
Abdul-Ghani, MA; Bhattacharya, A; Jang, YC; Liu, Y; Lustgarten, MS; Muller, FL; Van Remmen, H1
Cook, PF; Karsten, WE1
Andreo, CS; Drincovich, MF; Fahnenstich, H; Flügge, UI; Gerrard Weehler, MC; Maurino, VG; Tronconi, MA1
Nakamori, T; Ohno, Y; Suye, S; Zheng, H2
Cattivelli, L; Laus, MN; Pastore, D; Soccio, M; Trono, D1
Hagopian, K; Ramsey, JJ; Weindruch, R1
Contreras, L; Satrústegui, J1
Mendoza-Hernández, G; Nava, G; Plancarte, A1
Arvinte, A; Bala, C; Gurban, AM; Rotariu, L1
Tan, H; Tang, W; Zhang, S; Zhao, ZK1
Cao, ZY; Chen, LL; Ge, YD; Wang, ZD; Zhu, GP; Zhu, YM1
Dong, QL; Hao, YJ; Yao, YX; You, CX; Zhai, H1
Chen, HP; Chien, LF; Wu, YC1
Beard, DA; Dash, RK; Vinnakota, KC1
Giulivi, C; Luckhart, S; Napoli, E; Pon, J1
Abbrescia, DI; La Piana, G; Lofrumento, NE1
Baliutyte, G; Baniene, R; Borutaite, V; Gendviliene, V; Martisiene, I; Toleikis, A; Trumbeckaite, S1
Herppich, WB; Martin, CE; Peckmann, K; von Willert, DJ1
Chen, W; Ratledge, C; Song, Y; Vongsangnak, W; Zhang, Y1
Cousins, AB; Day, DA; Duffes, C; Gandin, A1
Kadokura, T; Kiyoshi, K; Kosugi, S; Kusumoto, K; Nakayama, S; Nakazato, A; Oba, T1
Deutch, CE1
Honda, K; Morimoto, Y; Ohtake, H; Okano, K; Ye, X1
Bratus', LV; Koliesnikova, IeE; Nosar, VI1
Columbus, JT; Edwards, GE; Koteyeva, NK; Ocampo, G; Sage, RF; Sage, TL; Voznesenskaya, EV1
Agarwal, B; Bosnjak, ZJ; Camara, AK; Dash, RK; Stowe, DF1
Hou, S; Ji, D; Liu, W; Wang, L; Zhao, ZK1
Gardeström, P; Igamberdiev, AU; Lernmark, U1
Alvarez, CE; Andreo, CS; Drincovich, MF; Golic, A; Hogenhout, SA; Mussi, MA; Saigo, M1
Aksentijević, D; Brookes, PS; Chouchani, ET; Costa, ASH; Dare, AJ; Davidson, SM; Duchen, MR; Eaton, S; Eyassu, F; Frezza, C; Gaude, E; Hartley, RC; Hu, CH; James, AM; Krieg, T; Logan, A; Murphy, MP; Nadtochiy, SM; Ord, ENJ; Pell, VR; Robb, EL; Robinson, AJ; Rogatti, S; Saeb-Parsy, K; Shattock, MJ; Shirley, R; Smith, AC; Sundier, SY; Work, LM1
Andreo, CS; Drincovich, MF; Martinatto, A; Tronconi, MA; Wheeler, MC; Zubimendi, JP1
Banke, NH; Lewandowski, ED1
Minteer, SD; Pelster, LN; Wu, F1
Levin, DB; Oresnik, IJ; Rydzak, T; Sparling, R; Taillefer, M1
Guan, KL; Lin, H; Ling, ZQ; Shi, Q; Xiong, Y; Yang, H; Yang, Y; Ye, D; Zhang, M; Zhao, S; Zhao, Y; Zhou, L1
Chen, J; Fernandez, J; Fernandez-Bueno, GA; Gusdon, AM; Mathews, CE; Wohlgemuth, S1
Carl, SM; Koppel, S; Michaelis, EK; Michaelis, ML; Ramanujan, S; Swerdlow, RH; Weidling, I; Wilkins, HM1
Calmettes, G; Korge, P; Weiss, JN1
Amoedo, ND; De Grassi, A; Lacombe, D; Obre, E; Pierri, CL; Punzi, G; Rossignol, R1
Hong, KM; Jang, H; Kang, JH; Kim, SY; Lee, C; Lee, JS; Lee, SH; Nam, B; Seong, TW; Son, J1
Chen, X; Dong, X; Liu, L; Qian, Y; Qiao, W; Wang, L; Wang, Y1
Cadenas, E; Casian, JG; Decker, CW; Han, D; Johnson, HS; Kaplowitz, N; Martin, G; Nguyen, KT; Rao, MP; Sancheti, H; Silkwood, KH1
Hong, D; Hong, KM; Kang, JH; Kim, SY; Lee, JS; Lee, SH; Son, J; Song, J1
Andreo, CS; Arias, CL; Badia, MB; Drincovich, MF; Gerrard Wheeler, MC; Lis, AV; Mans, R; Maurino, VG; Tronconi, MA; van Maris, AJ1
Banta, S; Garcia, KE; Ozbakir, HF1
Broom-Peltz, B; Chen, JCH; González, JM; Marti-Arbona, R; Unkefer, CJ1
Mizushima, T; Moriyama, S; Nishio, K1
Beyrath, J; Iannetti, EF; Koopman, WJH; Smeitink, JAM; Willems, PHGM1
Carvajal, F; Garrido, D; Jamilena, M; Jiménez-Muñoz, R; Palma, F; Pulido, A1
Bai, L; Guo, H; He, Y; Li, J; Luo, L; Ma, H; Wu, J; Xu, Q; Yu, H; Zhao, Y; Zhou, JM; Zuo, J1
Altinok, O; Bowne, WB; Orynbayeva, Z; Poggio, JL; Shieh, AC; Snyder, NW; Stein, DE1
Bertsova, YV; Bogachev, AV; Oleynikov, IP1
Belosludtsev, KN; Belosludtseva, NV; Khunderyakova, NV; Kireeva, TA; Mironova, GD1
Dao, O; Kuhnert, F; Li-Beisson, Y; Peltier, G; Weber, APM1
Akter, F; Jahan, I; Mimata, Y; Munemasa, S; Murata, Y; Nakamura, T; Nakamura, Y1
Amaral, AU; Marschner, RA; Ribeiro, RT; Roginski, AC; Wajner, M; Wajner, SM; Zemniaçak, ÂB1
Nakamura, A; Shimizu, T1
Fan, F; Qin, Y; Xi, Y; Xu, H; Zhan, T; Zhang, X1
Guss, AM; Harding, DJ; Karlsson, A; Kuil, T; Rydzak, T; van Maris, AJA; Yayo, J1
Chen, L; Huang, C; Huang, Q; Jia, D; Qu, X; Tao, J; Xu, X; Xu, Z1
Afzal, AR; Jeon, J; Jung, CH1

Reviews

3 review(s) available for nad and malic acid

ArticleYear
Aspects of helminth metabolism.
    Parasitology, 1982, Volume: 84, Issue:1

    Topics: Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Carbon Dioxide; Citric Acid Cycle; Cytochromes; Energy Metabolism; Fatty Acids; Fatty Acids, Volatile; Glucose; Glycogen; Helminths; Hemoglobins; Malates; Mitochondria; NAD; Oxidative Phosphorylation

1982
AGC1/2, the mitochondrial aspartate-glutamate carriers.
    Biochimica et biophysica acta, 2016, Volume: 1863, Issue:10

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Biological Transport, Active; Calcium-Binding Proteins; Cattle; Consensus Sequence; Glutamic Acid; Humans; Malates; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Models, Molecular; NAD; Neoplasm Proteins; Organ Specificity; Organic Anion Transporters; Oxidation-Reduction; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid

2016
Physiological functions of malate shuttles in plants and algae.
    Trends in plant science, 2022, Volume: 27, Issue:5

    Topics: Malates; NAD; Oxidation-Reduction; Photosynthesis

2022

Other Studies

190 other study(ies) available for nad and malic acid

ArticleYear
Oxidation of cytosolic NADH by the malate-aspartate shuttle in HuH13 human hepatoma cells.
    The International journal of biochemistry, 1992, Volume: 24, Issue:2

    Topics: Aspartic Acid; Carcinoma, Hepatocellular; Cytosol; Humans; Kinetics; Liver Neoplasms; Malates; NAD; Oxidation-Reduction; Tumor Cells, Cultured

1992
Effects of adenosine administration on the function and membrane composition of liver mitochondria in carbon tetrachloride-induced cirrhosis.
    Archives of biochemistry and biophysics, 1992, Volume: 294, Issue:1

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbon Tetrachloride; Cholesterol; Collagen; Electron Transport Complex IV; Energy Metabolism; Fluorescence Polarization; Intracellular Membranes; Liver Cirrhosis, Experimental; Malates; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; NAD; Oxidation-Reduction; Oxygen Consumption; Phospholipids; Rats; Rats, Inbred Strains

1992
Global ischaemia induces a biphasic response of the mitochondrial respiratory chain. Anoxic pre-perfusion protects against ischaemic damage.
    The Biochemical journal, 1992, Feb-01, Volume: 281 ( Pt 3)

    Topics: Animals; Buffers; Coronary Disease; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Glutamates; Glutamic Acid; Kinetics; Malates; Male; Mitochondria, Heart; Multienzyme Complexes; Myocardial Reperfusion Injury; NAD; NAD(P)H Dehydrogenase (Quinone); NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxidoreductases; Oxygen; Oxygen Consumption; Rats; Rats, Inbred Strains; Succinate Dehydrogenase; Time Factors

1992
Paraquat damage of rat liver mitochondria by superoxide production depends on extramitochondrial NADH.
    Toxicology, 1992, Volume: 72, Issue:1

    Topics: Animals; Benzoquinones; Cytochrome c Group; Free Radicals; Glucose-6-Phosphatase; Glutamates; Glutamic Acid; Malates; Male; Mice; Mice, Inbred ICR; Microscopy, Electron; Mitochondria, Liver; NAD; NADP; Paraquat; Rats; Rats, Inbred Strains; Rotenone; Superoxide Dismutase; Superoxides

1992
Interactions between mitochondria and cytoplasm in isolated hepatocytes.
    Current topics in cellular regulation, 1992, Volume: 33

    Topics: Animals; Aspartic Acid; Biological Transport; Cytoplasm; Energy Metabolism; Enzymes; Glucose; Glycolysis; Liver; Malates; Male; Mitochondria, Liver; Multienzyme Complexes; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains

1992
Operation and energy dependence of the reducing-equivalent shuttles during lactate metabolism by isolated hepatocytes.
    Biochimica et biophysica acta, 1992, Sep-09, Volume: 1136, Issue:3

    Topics: Ammonia; Animals; Aspartic Acid; Cytoplasm; Energy Metabolism; Gluconeogenesis; Lactates; Lactic Acid; Liver; Malates; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Palmitates; Rats; Rats, Inbred Strains; Valinomycin

1992
Kinetic studies of the regulation of mitochondrial malate dehydrogenase by citrate.
    The Biochemical journal, 1992, Apr-01, Volume: 283 ( Pt 1)

    Topics: Animals; Binding, Competitive; Chickens; Citrates; Hydrogen-Ion Concentration; Kinetics; Malate Dehydrogenase; Malates; Mathematical Computing; Mitochondria, Liver; NAD; Oxaloacetates

1992
Kinetics of the reduction of oxaloacetate catalyzed by mitochondrial malate dehydrogenase of Toxocara canis muscle.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1991, Volume: 98, Issue:2-3

    Topics: Animals; Dogs; Kinetics; Malate Dehydrogenase; Malates; Mitochondria, Muscle; NAD; Oxaloacetates; Oxidation-Reduction; Toxocara

1991
Acetoacetate and malate effects on succinate and energy production by O2-deprived liver mitochondria supplied with 2-oxoglutarate.
    Archives of biochemistry and biophysics, 1991, Volume: 287, Issue:2

    Topics: Acetoacetates; Adenosine Diphosphate; Adenosine Triphosphate; Anaerobiosis; Animals; Calcium; Citric Acid Cycle; Energy Metabolism; Ketoglutaric Acids; Malates; Mitochondria, Liver; NAD; Oligomycins; Oxygen; Phosphates; Rats; Rats, Inbred Strains; Rotenone; Succinates; Succinic Acid

1991
ATP-dependent and NAD-dependent modification of glutamine synthetase from Rhodospirillum rubrum in vitro.
    The Journal of biological chemistry, 1990, Aug-15, Volume: 265, Issue:23

    Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Immune Sera; Immunoblotting; Kinetics; Malates; Molecular Sequence Data; NAD; Peptide Fragments; Phosphorus Radioisotopes; Rhodospirillum rubrum

1990
Multiple isotope effects with alternative dinucleotide substrates as a probe of the malic enzyme reaction.
    Biochemistry, 1991, Jun-11, Volume: 30, Issue:23

    Topics: Animals; Ascaris; Carbon Isotopes; Chickens; Decarboxylation; Deuterium; Kinetics; Liver; Malate Dehydrogenase; Malates; NAD; NADP; Oxidation-Reduction; Substrate Specificity

1991
Purification and properties of a malolactic enzyme from Leuconostoc oenos ATCC 23278.
    Journal of basic microbiology, 1990, Volume: 30, Issue:8

    Topics: Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Ethanol; Hydrogen-Ion Concentration; Isoelectric Point; Lactates; Leuconostoc; Malate Dehydrogenase; Malates; Manganese; Molecular Weight; NAD; Temperature

1990
Acute and chronic ethanol treatment in vivo increases malate-aspartate shuttle capacity in perfused rat liver.
    The Journal of biological chemistry, 1990, Dec-15, Volume: 265, Issue:35

    Topics: Alanine; Aminooxyacetic Acid; Animals; Aspartic Acid; Biological Transport; Cytoplasm; Ethanol; Female; Glucose; Lactates; Liver; Malates; Mitochondria, Liver; NAD; Oxygen Consumption; Rats; Rats, Inbred Strains; Sorbitol; Time Factors

1990
An enzymatic cycling method for 3-acetylpyridine adenine dinucleotide to increase the sensitivity of enzymatic methods which employ this NAD analog.
    Analytical biochemistry, 1990, May-01, Volume: 186, Issue:2

    Topics: Coenzymes; Fluorometry; Indicators and Reagents; L-Lactate Dehydrogenase; Malate Dehydrogenase; Malates; NAD; Oxidation-Reduction

1990
Ascorbate as a source of reducing equivalents for the synthesis of aldosterone.
    Biochemical and biophysical research communications, 1990, Aug-16, Volume: 170, Issue:3

    Topics: Adrenal Glands; Aldehyde Oxidoreductases; Aldosterone; Animals; Ascorbic Acid; Cattle; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Drug Interactions; Malates; Mitochondria; NAD; NADP

1990
Metabolite transport in rat kidney mitochondria: ornithine/phosphate translocator.
    Biochemical and biophysical research communications, 1989, Feb-15, Volume: 158, Issue:3

    Topics: Animals; Biological Transport; Carrier Proteins; Fluorometry; Glutamates; Glutamic Acid; Kidney; Kinetics; Malates; Male; Membrane Transport Proteins; Mersalyl; Mitochondria; NAD; NADP; Ornithine; Oxidation-Reduction; Phosphates; Praseodymium; Rats; Rats, Inbred Strains; Spectrophotometry

1989
Structure and properties of malic enzyme from Bacillus stearothermophilus.
    The Journal of biological chemistry, 1989, Feb-25, Volume: 264, Issue:6

    Topics: Amino Acid Sequence; Base Sequence; Cations, Divalent; Cloning, Molecular; Codon; DNA, Bacterial; Escherichia coli; Geobacillus stearothermophilus; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Malate Dehydrogenase; Malates; Molecular Sequence Data; NAD; NADP; Oxaloacetates; Promoter Regions, Genetic; Pyruvates; Pyruvic Acid; Temperature

1989
Oxidation of cytosolic NADH by the malate-aspartate shuttle in MC29 hepatoma cells.
    Cell biology international reports, 1989, Volume: 13, Issue:9

    Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Chickens; Cytosol; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid

1989
Synthesis of malate from phosphoenolpyruvate by rabbit liver mitochondria: implications for lipogenesis.
    Biochimica et biophysica acta, 1988, Apr-14, Volume: 965, Issue:1

    Topics: Animals; Benzene Derivatives; Bicarbonates; Cyanides; Guanosine Diphosphate; Inosine Diphosphate; Lipids; Malates; Male; Malonates; Mitochondria, Liver; NAD; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Rabbits; Rats; Sodium; Sodium Bicarbonate; Tricarboxylic Acids

1988
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
    Life sciences, 1985, Jul-01, Volume: 36, Issue:26

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Diphosphate; Animals; Brain; Glutamates; Glutamic Acid; Malates; Male; Mice; Mitochondria; NAD; Neurotoxins; Oxidation-Reduction; Phosphorylation; Pyridines; Rats; Rats, Inbred Strains

1985
Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+.
    Biochemical and biophysical research communications, 1986, Jan-29, Volume: 134, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport, Active; Electron Transport; Glutamates; Glutamic Acid; Intracellular Membranes; Malates; Mitochondria, Heart; Mitochondria, Liver; NAD; NAD(P)H Dehydrogenase (Quinone); Pyridinium Compounds; Quinone Reductases; Rats; Succinates; Succinic Acid

1986
In vivo and in vitro adenosine stimulation of ethanol oxidation by hepatocytes, and the role of the malate-aspartate shuttle.
    Biochimica et biophysica acta, 1987, Sep-14, Volume: 930, Issue:2

    Topics: Adenosine; Animals; Aspartic Acid; Ethanol; Glutamates; Glutamic Acid; In Vitro Techniques; Liver; Malates; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains

1987
The mechanism of lead-induced mitochondrial Ca2+ efflux.
    Journal of bioenergetics and biomembranes, 1987, Volume: 19, Issue:3

    Topics: Animals; Biological Transport, Active; Calcium; Glutamates; Glutamic Acid; In Vitro Techniques; Kidney Cortex; Lead; Malates; Membrane Potentials; Mitochondria; NAD; Rabbits; Succinates; Succinic Acid; Sulfhydryl Compounds

1987
Changes in pyridine nucleotide levels alter oxygen consumption and extra-mitochondrial phosphates in isolated mitochondria: a 31P-NMR and NAD(P)H fluorescence study.
    Biochimica et biophysica acta, 1987, Oct-07, Volume: 893, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fluorescent Dyes; Glutamates; Glutamic Acid; Magnetic Resonance Spectroscopy; Malates; Male; Mitochondria, Liver; NAD; NADP; Oxygen Consumption; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Rhodamines; Spectrometry, Fluorescence

1987
Cardiac mitochondrial abnormalities in a mouse model of the fetal alcohol syndrome.
    Alcoholism, clinical and experimental research, 1988, Volume: 12, Issue:2

    Topics: Animals; Animals, Newborn; Electron Transport Complex IV; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetus; Gestational Age; Glutamates; Glutamic Acid; Malates; Mice; Mitochondria, Heart; NAD; Oxygen Consumption; Pregnancy; Succinate Dehydrogenase; Succinates; Succinic Acid

1988
Palmitoyl carnitine: an endogenous promotor of calcium efflux from rat heart mitochondria.
    Biochemical pharmacology, 1988, Aug-15, Volume: 37, Issue:16

    Topics: Animals; Calcium; Carnitine; Female; Glutamates; Glutamic Acid; Malates; Mitochondria, Heart; NAD; Oxidation-Reduction; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Succinates; Succinic Acid

1988
Diet effects on membrane phospholipid fatty acids and mitochondrial function in BHE rats.
    The Journal of nutrition, 1986, Volume: 116, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Aspartic Acid; Coconut Oil; Corn Oil; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Fatty Acids; Glycerophosphates; Malates; Male; Membrane Lipids; Mitochondria, Liver; NAD; Oils; Phospholipids; Plant Oils; Rats; Rats, Mutant Strains

1986
Malate-citrate cycle during glycolysis and glutaminolysis in Ehrlich ascites tumor cells.
    Biochimie, 1987, Volume: 69, Issue:5

    Topics: Animals; Benzene Derivatives; Carcinoma, Ehrlich Tumor; Citrates; Citric Acid; Cytosol; Female; Glucose; Glutamine; Glycolysis; Malate Dehydrogenase; Malates; Mice; Mitochondria; NAD; Oxygen Consumption; Tricarboxylic Acids

1987
A general coupled spectrophotometric assay for decarboxylases.
    Analytical biochemistry, 1988, Volume: 171, Issue:2

    Topics: Carbon Dioxide; Carboxy-Lyases; Chemical Phenomena; Chemistry; Decarboxylation; Malates; Multienzyme Complexes; NAD; Oxidation-Reduction; Peptide Synthases; Spectrophotometry

1988
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), cyperquat (MPP+) and paraquat on isolated mitochondria from rat striatum, cortex and liver.
    Life sciences, 1988, Volume: 43, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Animals; Cerebral Cortex; Corpus Striatum; Flavin-Adenine Dinucleotide; Malates; Mitochondria; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Paraquat; Phosphorylation; Pyridines; Pyridinium Compounds; Pyruvates; Pyruvic Acid; Rats; Succinates; Succinic Acid

1988
Photosynthesis in phosphoenolpyruvate carboxykinase-type C4 plants: activity and role of mitochondria in bundle sheath cells.
    Archives of biochemistry and biophysics, 1988, Volume: 261, Issue:2

    Topics: Adenosine Diphosphate; Carbon; Decarboxylation; Electron Transport; Malates; Mitochondria; NAD; NADP; Oxygen Consumption; Phosphoenolpyruvate Carboxykinase (GTP); Photosynthesis; Plants; Pyruvates

1988
Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.
    Journal of neurochemistry, 1986, Volume: 46, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Amino Acids; Animals; Brain; Corpus Striatum; Malates; Male; Mice; Mitochondria; NAD; Oxidation-Reduction; Oxygen Consumption; Pyridines; Pyridinium Compounds; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1986
Quantitation of the interaction between citrate synthase and malate dehydrogenase.
    The Journal of biological chemistry, 1987, May-05, Volume: 262, Issue:13

    Topics: Adenosine Triphosphate; Animals; Citrate (si)-Synthase; Citrates; Citric Acid; Fluorescence Polarization; Ketoglutaric Acids; Malate Dehydrogenase; Malates; Mitochondria, Heart; NAD; Oxaloacetates; Oxo-Acid-Lyases; Swine

1987
Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates.
    Biochimica et biophysica acta, 1987, Sep-14, Volume: 930, Issue:2

    Topics: Acetates; Aminooxyacetic Acid; Animals; Aspartic Acid; Glycolysis; Guinea Pigs; In Vitro Techniques; Malates; Membrane Potentials; Mitochondria; NAD; Onium Compounds; Organophosphorus Compounds; Oxygen Consumption; Synaptosomes

1987
Organic aciduria in rats fed high amounts of xylitol or sorbitol.
    Toxicology and applied pharmacology, 1987, Sep-15, Volume: 90, Issue:2

    Topics: Animals; Body Weight; Citrates; Citric Acid; Cytoplasm; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Ketoglutaric Acids; Malates; Male; Malonates; Methylmalonic Acid; NAD; Oxalates; Oxalic Acid; Rats; Rats, Inbred Strains; Sorbitol; Xylitol

1987
Stimulatory effect of ADP, ATP, NAD(P) on pyruvate production from malate by uncoupled human placental mitochondria.
    Biochemical medicine and metabolic biology, 1987, Volume: 38, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Malate Dehydrogenase; Malates; Mitochondria; NAD; Placenta; Pregnancy; Pyruvates; Pyruvic Acid

1987
Importance of the malate-aspartate shuttle for the reoxidation of glycolytically produced NADH and for cell aggregation in porcine blood platelets.
    Acta biochimica Polonica, 1987, Volume: 34, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Blood Platelets; Cytosol; Glycolysis; Malate Dehydrogenase; Malates; Mitochondria; NAD; Oxidation-Reduction; Oxygen Consumption; Platelet Aggregation; Swine; Uncoupling Agents

1987
Intracellular distribution of some enzymes of the glutamine utilisation pathway in rat lymphocytes.
    Biochemical and biophysical research communications, 1986, Jul-16, Volume: 138, Issue:1

    Topics: Animals; Aspartate Aminotransferases; Cell Compartmentation; Cytosol; Glutamine; Lymphocytes; Malate Dehydrogenase; Malates; Mitochondria; NAD; Oxaloacetates; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvate Carboxylase; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats

1986
[Effect of malate and NAD on local myocardial contraction during acute coronary occlusion].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 102, Issue:9

    Topics: Animals; Blood Pressure; Cats; Coronary Disease; Malates; Myocardial Contraction; NAD

1986
Inhibition by hydroxymalonate of malate dependent biosynthesis of progesterone in the mitochondrial fraction of human term placenta.
    Journal of steroid biochemistry, 1987, Volume: 26, Issue:1

    Topics: Cholesterol; Female; Humans; Malate Dehydrogenase; Malates; Mitochondria; NAD; NADP; Placenta; Progesterone; Tartronates

1987
Effect of redox potential on protein degradation in perfused rat heart.
    The American journal of physiology, 1985, Volume: 248, Issue:6 Pt 1

    Topics: Animals; Glucose; Heart; Insulin; Leucine; Malates; Male; Myocardium; NAD; Oxidation-Reduction; Perfusion; Phenylalanine; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1985
Functional studies on in situ-like mitochondria isolated in the presence of polyvinyl pyrrolidone.
    Biochimica et biophysica acta, 1985, Jan-23, Volume: 806, Issue:1

    Topics: Adenosine Diphosphate; Animals; Cell Fractionation; Coenzyme A; Cricetinae; Malates; Mesocricetus; Microscopy, Electron; Mitochondria, Heart; Mitochondrial Swelling; NAD; Oxygen Consumption; Povidone; Pyruvates; Pyruvic Acid

1985
Oxidative metabolism of Polytron versus Nagarse mitochondria in hearts of genetically diabetic mice.
    Biochimica et biophysica acta, 1985, Jan-23, Volume: 806, Issue:1

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Animals; Cell Fractionation; Diabetes Mellitus, Experimental; Malates; Mice; Mice, Inbred C57BL; Microscopy, Electron; Mitochondria, Heart; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Palmitoylcarnitine; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid

1985
The role of malic enzyme in the malate dependent biosynthesis of progesterone in the mitochondrial fraction of human term placenta.
    Journal of steroid biochemistry, 1985, Volume: 22, Issue:3

    Topics: Citrates; Citric Acid; Female; Humans; Malate Dehydrogenase; Malates; Mitochondria; NAD; NADP; Placenta; Pregnancy; Progesterone

1985
Diethylpyrocarbonate inactivation of NAD-malic enzyme from Ascaris suum.
    Archives of biochemistry and biophysics, 1985, Aug-15, Volume: 241, Issue:1

    Topics: Animals; Ascaris; Binding Sites; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Malate Dehydrogenase; Malates; NAD; Spectrometry, Fluorescence

1985
Substrate channeling of oxalacetate in solid-state complexes of malate dehydrogenase and citrate synthase.
    The Journal of biological chemistry, 1985, Dec-05, Volume: 260, Issue:28

    Topics: Animals; Citrate (si)-Synthase; Citrates; Citric Acid; Coenzyme A; Kinetics; Malate Dehydrogenase; Malates; Models, Chemical; Multienzyme Complexes; Myocardium; NAD; Oxaloacetates; Oxo-Acid-Lyases; Polyethylene Glycols; Swine

1985
Effect of fatty acids and ketones on the activity of pyruvate dehydrogenase in skeletal-muscle mitochondria.
    The Biochemical journal, 1983, Sep-15, Volume: 214, Issue:3

    Topics: Acetoacetates; Animals; Calcium; Coenzyme A; Fatty Acids; Glutamates; Glutamic Acid; In Vitro Techniques; Ketoglutaric Acids; Ketones; Malates; Male; Mitochondria, Muscle; NAD; Oxygen Consumption; Palmitoylcarnitine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains

1983
Formation of glycine and aminoacetone from L-threonine by rat liver mitochondria.
    Biochimica et biophysica acta, 1984, Nov-28, Volume: 802, Issue:2

    Topics: Acetone; Animals; Coenzyme A; Freezing; Glycine; Malates; Male; Mitochondria, Liver; NAD; Rats; Rats, Inbred Strains; Sonication; Threonine

1984
Modulation of the activity of NAD malic enzyme from solanum tuberosum by changes in oligomeric state.
    Archives of biochemistry and biophysics, 1984, Nov-01, Volume: 234, Issue:2

    Topics: Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Malate Dehydrogenase; Malates; NAD; Osmolar Concentration; Plants; Sodium Chloride; Vegetables

1984
Kinetic mechanism in the direction of oxidative decarboxylation for NAD-malic enzyme from Ascaris suum.
    Biochemistry, 1984, Nov-06, Volume: 23, Issue:23

    Topics: Animals; Ascaris; Binding, Competitive; Kinetics; Magnesium; Malate Dehydrogenase; Malates; NAD; Pyruvates; Pyruvic Acid; Tartronates

1984
Determination of dissociation constants for enzyme-reactant complexes for NAD-malic enzyme by modulation of the thiol inactivation rate.
    Biochemistry, 1984, Nov-06, Volume: 23, Issue:23

    Topics: Animals; Ascaris; Disulfides; Dithionitrobenzoic Acid; Ethylmaleimide; Hydrogen-Ion Concentration; Kinetics; Magnesium; Malate Dehydrogenase; Malates; Manganese; NAD; Pyridines; Sulfhydryl Compounds; Sulfhydryl Reagents

1984
A facile method for the isolation of porcine heart mitochondrial malate dehydrogenase by affinity elution chromatography on Procion Red HE3B.
    Bioscience reports, 1983, Volume: 3, Issue:11

    Topics: Animals; Chromatography, Affinity; Coloring Agents; Malate Dehydrogenase; Malates; Mitochondria, Heart; NAD; Swine; Triazines

1983
Metabolic control and compartmentation in single living cells.
    Cell biochemistry and function, 1983, Volume: 1, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Compartmentation; Cell Line; Cells, Cultured; Flavins; Glucose-6-Phosphate; Glucosephosphates; Glycolysis; Malates; Mathematics; Mice; Mitochondria; NAD; NADP; Oxidation-Reduction; Oxidative Phosphorylation; Rats; Spectrometry, Fluorescence

1983
The differential effects of dimethylnitrosamine and ethionine on mitochondrial and extramitochondrial dehydrogenases in single intact cells.
    Biochimica et biophysica acta, 1984, Feb-17, Volume: 803, Issue:1-2

    Topics: Animals; Cells, Cultured; Dimethylnitrosamine; Ethionine; Glucosephosphates; Glycolysis; Malates; Mice; Mitochondria; NAD; NADP; Neoplasms, Experimental; Oxidoreductases

1984
Evidence for the role of malic enzyme in the rapid oxidation of malate by cod heart mitochondria.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1984, Volume: 77, Issue:2

    Topics: Animals; Fishes; Malate Dehydrogenase; Malates; Mitochondria, Heart; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rabbits; Rats; Species Specificity

1984
Regulation of malate oxidation in plant mitochondria. Response to rotenone and exogenous NAD+.
    The Biochemical journal, 1982, Dec-15, Volume: 208, Issue:3

    Topics: Adenosine Diphosphate; Egtazic Acid; Malates; Mitochondria; NAD; Oxidation-Reduction; Plants; Rotenone

1982
Malolactic enzyme of Lactobacillus plantarum. Purification, properties, and distribution among bacteria.
    The Journal of biological chemistry, 1983, Apr-25, Volume: 258, Issue:8

    Topics: Electrophoresis, Polyacrylamide Gel; Isoelectric Point; Lactates; Lactic Acid; Lactobacillus; Malate Dehydrogenase; Malates; Manganese; Molecular Weight; NAD

1983
Changes in NAD(P)+-dependent malic enzyme and malate dehydrogenase activities during fibroblast proliferation.
    Journal of cellular physiology, 1982, Volume: 110, Issue:2

    Topics: Cell Division; Cell Fractionation; Cells, Cultured; Fibroblasts; Humans; Lactates; Lactic Acid; Malate Dehydrogenase; Malates; Manganese; Mitochondria; NAD; NADP; Oxaloacetates; Pyruvates; Pyruvic Acid

1982
Relationship of the reduction-oxidation state to protein degradation in skeletal and atrial muscle.
    Archives of biochemistry and biophysics, 1982, Volume: 217, Issue:1

    Topics: Animals; Diaphragm; Heart Atria; Lactates; Lactic Acid; Leucine; Malates; Male; Muscle Proteins; Muscles; NAD; Oxidation-Reduction; Protease Inhibitors; Pyruvates; Pyruvic Acid; Rats

1982
Spin ECHO proton NMR studies of the metabolism of malate and fumarate in human erythrocytes. Dependence on free NAD levels.
    Biochimica et biophysica acta, 1982, Oct-11, Volume: 721, Issue:2

    Topics: Biological Transport; Erythrocytes; Fumarate Hydratase; Fumarates; Humans; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Malates; NAD

1982
Bioluminescent assays of picomole levels of various metabolites using immobilized enzymes.
    Analytical biochemistry, 1982, Volume: 127, Issue:2

    Topics: Alanine; Enzymes, Immobilized; FMN Reductase; Gluconates; Glucose; Glutamates; Lactates; Luciferases; Luminescent Measurements; Malates; Microchemistry; NAD; NADH, NADPH Oxidoreductases; NADP

1982
Capacity of the malate/oxaloacetate shuttle for transfer of reducing equivalents across the envelope of leaf chloroplasts.
    Archives of biochemistry and biophysics, 1982, Volume: 219, Issue:2

    Topics: Biological Transport; Chloroplasts; Kinetics; Malate Dehydrogenase; Malates; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Plants

1982
Influence of pH on the kinetic mechanism of chicken liver cytoplasmic malate dehydrogenase (B form).
    The International journal of biochemistry, 1981, Volume: 13, Issue:4

    Topics: Animals; Cytoplasm; Hydrogen-Ion Concentration; Kinetics; Liver; Malate Dehydrogenase; Malates; NAD; Oxaloacetates

1981
Reducing equivalent shuttles in developing porcine myocardium: enhanced capacity in the newborn heart.
    Pediatric research, 1995, Volume: 38, Issue:2

    Topics: Adenosine Triphosphate; Aerobiosis; Animals; Animals, Newborn; Aspartic Acid; Biological Transport; Glycerophosphates; Heart; Malates; Mitochondria, Heart; Myocardial Contraction; NAD; Oxidation-Reduction; Swine

1995
Transhydrogenase activities and malate dismutation linked to fumarate reductase system in the filarial parasite Setaria digitata.
    International journal for parasitology, 1995, Volume: 25, Issue:7

    Topics: Adenosine Triphosphate; Animals; Cattle; Energy Metabolism; Fumarate Hydratase; Humans; Malate Dehydrogenase; Malates; Mitochondria; NAD; NADP; NADP Transhydrogenases; Setaria Nematode; Succinate Dehydrogenase

1995
Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes.
    European journal of biochemistry, 1995, Jul-15, Volume: 231, Issue:2

    Topics: 2,4-Dinitrophenol; Adenine Nucleotides; Animals; Aspartic Acid; Caprylates; Cell Separation; Dihydroxyacetone; Dinitrophenols; Electron Transport; Fatty Acids; Glucose; Lactates; Lactic Acid; Liver; Malates; Male; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1995
[The drug "anfen" and the energy status of the liver].
    Doklady Akademii nauk, 1995, Volume: 340, Issue:4

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Electron Spin Resonance Spectroscopy; Energy Metabolism; Glutamic Acid; Kinetics; Malates; Male; Malonates; Mitochondria, Liver; NAD; Oxygen; Phospholipids; Rats; Rats, Wistar

1995
Calcium and 2-oxoglutarate-mediated control of aspartate formation by rat heart mitochondria.
    European journal of biochemistry, 1994, Aug-01, Volume: 223, Issue:3

    Topics: Animals; Aspartic Acid; Calcium; Dinitrophenols; Enzyme Activation; Glutamates; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Malates; Membrane Potentials; Mitochondria, Heart; Models, Biological; NAD; Pyruvates; Pyruvic Acid; Rats

1994
Oxidation of NADH by a rotenone and antimycin-sensitive pathway in the mitochondrion of procyclic Trypanosoma brucei brucei.
    Molecular and biochemical parasitology, 1994, Volume: 64, Issue:1

    Topics: Animals; Antimycin A; Electron Transport; Electron Transport Complex I; Glucose; Malates; Malonates; Mitochondria; NAD; NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Protozoan Proteins; Rotenone; Succinate Cytochrome c Oxidoreductase; Succinate Dehydrogenase; Trypanosoma brucei brucei

1994
Effect of L-malate on pyruvate dehydrogenase activity of spermatozoa.
    Archives of biochemistry and biophysics, 1994, Feb-01, Volume: 308, Issue:2

    Topics: Animals; Kinetics; Lactates; Malates; Male; Mice; Mitochondria; Mitochondria, Liver; NAD; Organ Specificity; Oxidation-Reduction; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex; Pyruvates; Rabbits; Rats; Spermatozoa

1994
Cooperativity in the mechanism of malate dehydrogenase.
    Biochemistry, 1993, Nov-30, Volume: 32, Issue:47

    Topics: Allosteric Regulation; Animals; Kinetics; Malate Dehydrogenase; Malates; Myocardium; NAD; Oxidation-Reduction; Swine

1993
Oxidation of pyruvate, malate, citrate, and cytosolic reducing equivalents by AS-30D hepatoma mitochondria.
    Archives of biochemistry and biophysics, 1993, Aug-15, Volume: 305, Issue:1

    Topics: Aconitate Hydratase; Animals; Citrates; Citric Acid; Citric Acid Cycle; Cytosol; Electrochemistry; Fatty Acids; Female; Isocitrate Dehydrogenase; Kinetics; Liver Neoplasms, Experimental; Malate Dehydrogenase; Malates; Mitochondria, Liver; NAD; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley

1993
Organic acid activation of the alternative oxidase of plant mitochondria.
    FEBS letters, 1993, Aug-30, Volume: 329, Issue:3

    Topics: Enzyme Activation; Glycine max; Malates; Mitochondria; NAD; Oxidation-Reduction; Oxidoreductases; Oxygen; Pyruvates; Pyruvic Acid; Substrate Specificity; Succinates; Succinic Acid

1993
Luminometric measurement of subnanomole amounts of key metabolites in extracts from isolated heart muscle cells.
    Analytical biochemistry, 1996, Jul-15, Volume: 239, Issue:1

    Topics: Animals; Biological Assay; Citrates; Citric Acid; Female; Glucose-6-Phosphate; Glucosephosphates; Ketoglutaric Acids; Luminescent Measurements; Malates; Microchemistry; Myocardium; NAD; Rats; Rats, Sprague-Dawley

1996
Role of the divalent metal ion in the NAD:malic enzyme reaction: an ESEEM determination of the ground state conformation of malate in the E:Mn:malate complex.
    Protein science : a publication of the Protein Society, 1996, Volume: 5, Issue:8

    Topics: Animals; Ascaris suum; Binding Sites; Cations, Divalent; Deuterium; Electron Spin Resonance Spectroscopy; Malate Dehydrogenase; Malates; Manganese; NAD; Protein Binding; Protein Conformation; Spin Labels; Stereoisomerism; Structure-Activity Relationship

1996
Purification and kinetic characterization of Haemophilus parasuis malate dehydrogenase.
    Archives of biochemistry and biophysics, 1997, Aug-01, Volume: 344, Issue:1

    Topics: Adenosine; Adenosine Diphosphate; Chromatography, Gel; Coenzymes; Dimerization; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Haemophilus; Kinetics; Malate Dehydrogenase; Malates; Molecular Weight; NAD; Nicotinyl Alcohol; Protein Denaturation; Substrate Specificity; Temperature

1997
NADP-malic enzyme from the C4 plant Flaveria bidentis: nucleotide substrate specificity.
    Archives of biochemistry and biophysics, 1997, Sep-15, Volume: 345, Issue:2

    Topics: Animals; Cations, Divalent; Chickens; Hydrogen-Ion Concentration; Kinetics; Liver; Malate Dehydrogenase; Malates; NAD; NADP; Photosynthesis; Plants; Species Specificity; Substrate Specificity

1997
Fumarate permeation in normal and acidotic rat kidney mitochondria: fumarate/malate and fumarate/aspartate translocators.
    Biochemical and biophysical research communications, 1998, Feb-24, Volume: 243, Issue:3

    Topics: Acidosis; Adenylosuccinate Lyase; Animals; Aspartic Acid; Biological Transport; Carrier Proteins; Fumarates; Kidney; Malates; Male; Mitochondria; NAD; NADP; Oxaloacetates; Rats; Rats, Wistar

1998
Ontogeny of malate-aspartate shuttle capacity and gene expression in cardiac mitochondria.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Base Sequence; Biological Transport; DNA, Complementary; Down-Regulation; Gene Expression; Malate Dehydrogenase; Malates; Mitochondria, Heart; Molecular Sequence Data; NAD; RNA, Messenger; Swine

1998
Energy dependence of protein synthesis by isolated cestode mitochondria.
    Archives of physiology and biochemistry, 1997, Volume: 105, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Energy Metabolism; Gene Expression Regulation; Helminth Proteins; Hymenolepis; Malates; Mitochondria; NAD; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley

1997
A method for the isolation of tegument syncytium mitochondria from Taenia crassiceps cysticerci and partial characterization of their aerobic metabolism.
    The Journal of parasitology, 1998, Volume: 84, Issue:3

    Topics: Animals; Cell Fractionation; Cell Membrane; Cysticercus; Female; Glutamic Acid; Malates; Membrane Potentials; Mice; Microscopy, Electron; Mitochondria; NAD; Oxidative Phosphorylation; Oxygen Consumption; Saponins; Solubility; Succinate Dehydrogenase; Succinates

1998
Luminometric measurement of malate and glucose-6-phosphate in mammalian tissue.
    Methods in molecular biology (Clifton, N.J.), 1998, Volume: 102

    Topics: Animals; Buffers; Flavin Mononucleotide; Glucose-6-Phosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Luminescent Measurements; Malates; Myocardium; NAD; NADP; Photometry; Rats; Rats, Sprague-Dawley; Solutions

1998
Malate-aspartate shuttle, cytoplasmic NADH redox potential, and energetics in vascular smooth muscle.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:8

    Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Biological Transport; Cytoplasm; Energy Metabolism; Glucose; Malates; Mitochondria, Muscle; Muscle Contraction; Muscle, Smooth, Vascular; NAD; Oxidation-Reduction; Oxygen Consumption; Phosphates; Swine

1998
Quinone analogue irrecoverably paralyses the filarial parasites in vitro.
    Biochemical and biophysical research communications, 1999, Mar-05, Volume: 256, Issue:1

    Topics: Animals; Benzoquinones; Cattle; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Transport; Filariasis; Fumarates; Glucose; Humans; Malates; Movement; NAD; Setaria Nematode; Setariasis; Sodium Lactate; Time Factors; Wuchereria bancrofti

1999
Alpha-secondary tritium kinetic isotope effects indicate hydrogen tunneling and coupled motion occur in the oxidation of L-malate by NAD-malic enzyme.
    Biochemistry, 1999, Apr-06, Volume: 38, Issue:14

    Topics: Animals; Ascaris suum; Cattle; Deuterium; Kinetics; Malate Dehydrogenase; Malates; NAD; Oxidation-Reduction; Protons; Substrate Specificity; Tritium

1999
Glutamate neurotoxicity in rat cerebellar granule cells involves cytochrome c release from mitochondria and mitochondrial shuttle impairment.
    Journal of neurochemistry, 1999, Volume: 73, Issue:1

    Topics: Animals; Cells, Cultured; Cerebellum; Cytochrome c Group; Dihydroxyacetone Phosphate; Electron Transport Complex II; Electron Transport Complex III; Glutamic Acid; Glycerophosphates; Malates; Mitochondria; Multienzyme Complexes; NAD; NAD(P)H Dehydrogenase (Quinone); Oxaloacetic Acid; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Rats; Succinate Dehydrogenase

1999
Metabolic adaptation of the hypertrophied heart: role of the malate/aspartate and alpha-glycerophosphate shuttles.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:12

    Topics: Adenosine Triphosphate; Animals; Aorta; Aspartic Acid; Atrial Natriuretic Factor; Blotting, Northern; Cardiomegaly; Fatty Acids; Glucose; Glycerophosphates; Immunoblotting; Lactic Acid; Malate Dehydrogenase; Malates; Male; Mitochondria; Models, Biological; Myocardium; NAD; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors

2000
Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:3

    Topics: Adenosine Triphosphate; Aspartic Acid; Citric Acid Cycle; Energy Metabolism; Fatty Acids, Nonesterified; Flavin-Adenine Dinucleotide; Fumarate Hydratase; Gene Deletion; Glucose; Glycerophosphates; Glycolysis; Humans; Lactic Acid; Malates; Mitochondria; Models, Biological; Mutation; NAD; Oxygen Consumption; Palmitic Acid; Phosphofructokinase-1; Pyruvate Dehydrogenase Complex

2001
Paradoxical effects of copper and manganese on brain mitochondrial function.
    Life sciences, 2001, Feb-23, Volume: 68, Issue:14

    Topics: 2,6-Dichloroindophenol; Animals; Brain Chemistry; Coloring Agents; Copper; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Malates; Male; Manganese; Mitochondria; Monoamine Oxidase; NAD; Oxidation-Reduction; Rats; Rats, Wistar; Succinic Acid

2001
Substrate and cofactor binding to fluorescently labeled cytoplasmic malate dehydrogenase.
    Biochimica et biophysica acta, 2001, Feb-09, Volume: 1545, Issue:1-2

    Topics: Animals; Binding Sites; Binding, Competitive; Cytoplasm; Enzyme Inhibitors; Fluorescent Dyes; Fluorometry; Isoenzymes; Ligands; Malate Dehydrogenase; Malates; Models, Molecular; Muscle Proteins; Myocardium; NAD; Naphthalenesulfonates; Oxaloacetates; Peptide Fragments; Protein Binding; Swine; Tartronates

2001
Assimilation of D-malate by Rhodobacter capsulatus E1F1.
    Current microbiology, 2001, Volume: 43, Issue:3

    Topics: Chromatography, Ion Exchange; Culture Media; Enzyme Induction; Malate Dehydrogenase; Malates; Manganese; NAD; Oxidation-Reduction; Racemases and Epimerases; Rhodobacter capsulatus; Stereoisomerism

2001
Changes in activities of enzymes related to malate-aspartate shuttle in leukocytes from dogs given a herb supplement.
    The Journal of veterinary medical science, 2001, Volume: 63, Issue:6

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Blood Glucose; Dietary Supplements; Dogs; Drugs, Chinese Herbal; Fatty Acids, Nonesterified; Female; Glutamate Dehydrogenase; Insulin; L-Lactate Dehydrogenase; Leukocytes; Malate Dehydrogenase; Malates; Male; NAD; Triglycerides

2001
Analysis of reactive oxygen species generating systems in rat epididymal spermatozoa.
    Biology of reproduction, 2001, Volume: 65, Issue:4

    Topics: Animals; Cell Membrane; Epididymis; Lactic Acid; Leukocytes; Malates; Male; Mitochondria; NAD; NADP; NADPH Oxidases; Oligomycins; Onium Compounds; Oxidation-Reduction; Rats; Reactive Oxygen Species; Rotenone; Spermatozoa; Succinic Acid; Superoxides; Uncoupling Agents; Zinc

2001
DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria.
    Journal of neurochemistry, 2001, Volume: 79, Issue:2

    Topics: Animals; Brain; Glutamic Acid; Malates; Membrane Potentials; Mitochondria; NAD; Oxygen Consumption; Rats; Reactive Oxygen Species; Succinic Acid

2001
Activities of enzymes in the malate-aspartate shuttle in the peripheral leukocytes of dogs and cats.
    Veterinary research communications, 2001, Volume: 25, Issue:8

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Blood Glucose; Cats; Cytosol; Dogs; Fatty Acids, Nonesterified; Female; Gene Expression; Glutamate Dehydrogenase; Insulin; L-Lactate Dehydrogenase; Leukocytes; Malate Dehydrogenase; Malates; Male; Mitochondria; NAD; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triglycerides

2001
Rotenone-insensitive NADH dehydrogenase is a potential source of superoxide in procyclic Trypanosoma brucei mitochondria.
    Molecular and biochemical parasitology, 2002, Aug-28, Volume: 123, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antimycin A; Biphenyl Compounds; Fumarates; Malates; Methacrylates; Mitochondria; NAD; NADH Dehydrogenase; Onium Compounds; Polyenes; Proline; Rotenone; Substrate Specificity; Succinic Acid; Superoxides; Thiazoles; Trypanosoma brucei brucei; Ubiquinone; Uncoupling Agents

2002
Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD.
    Biochemistry, 2002, Oct-08, Volume: 41, Issue:40

    Topics: Alcohol Oxidoreductases; Carbon Isotopes; Catalysis; Deuterium; Hydrogen-Ion Concentration; Kinetics; Malates; NAD; Oxaloacetic Acid; Pseudomonas putida

2002
External alternative NADH dehydrogenase of Saccharomyces cerevisiae: a potential source of superoxide.
    Free radical biology & medicine, 2003, Feb-15, Volume: 34, Issue:4

    Topics: Antifungal Agents; Antimycin A; Electron Transport Complex III; Hydrogen Peroxide; Malates; Methacrylates; Mitochondria; NAD; NADH Dehydrogenase; Polyenes; Rotenone; Saccharomyces cerevisiae; Succinic Acid; Superoxides; Thiazoles

2003
Phloem metabolism and function have to cope with low internal oxygen.
    Plant physiology, 2003, Volume: 131, Issue:4

    Topics: Adaptation, Physiological; Adenosine Triphosphate; Amino Acids; Biological Transport, Active; Energy Metabolism; Fermentation; Glycolysis; Malates; NAD; Oxygen; Phosphorus; Plant Structures; Ricinus; Seedlings; Succinic Acid; Sucrose

2003
The free-energy changes for the reduction of diphosphopyridine nucleotide and the dehydrogenation of L-malate and L-glycerol 1-phosphate.
    The Biochemical journal, 1953, Volume: 54, Issue:1

    Topics: Coenzymes; Glycerophosphates; Malates; NAD; Oxidoreductases

1953
[Determination of L-lactate, L-malate, L-glutamate and ethyl alcohol in the enzyme-optic test by means of the DPN analog, 3-acetylpyridine-DPN].
    Biochemische Zeitschrift, 1962, Volume: 336

    Topics: Ethanol; Glutamates; Glutamic Acid; L-Lactate Dehydrogenase; Lactates; Malate Dehydrogenase; Malates; NAD; Oxidoreductases; Pyridines

1962
GLYCOLIC ACID OXIDATION BY ESCHERICHIA COLI ADAPTED TO GLYCOLATE.
    Journal of bacteriology, 1963, Volume: 85

    Topics: Azides; Citrates; Cyanides; Edetic Acid; Enzyme Inhibitors; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glycolates; Hydroxybutyrates; Indophenol; Iodoacetates; Lactates; Malates; Manometry; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Phenanthrolines; Potassium; Research; Tartrates

1963
[ENZYMATIC DETERMINATION OF BLOOD L-MALIC ACID].
    Bulletin de la Societe de chimie biologique, 1963, Aug-31, Volume: 45

    Topics: Blood Chemical Analysis; Erythrocytes; Glucose; Keto Acids; Ketoglutaric Acids; Malate Dehydrogenase; Malates; NAD; Research; Spectrophotometry

1963
DENATURATION AND RENATURATION OF MALIC DEHYDROGENASE IN A CELL-FREE EXTRACT FROM A MARINE PSYCHROPHILE.
    Journal of bacteriology, 1963, Volume: 86

    Topics: Bacteria; Hot Temperature; Kinetics; Malate Dehydrogenase; Malates; Marine Biology; Metabolism; NAD; Oregon; Research; Temperature; Vibrio

1963
SYNTHESIS OF GLUTAMATE FROM ALPHA-OXOGLUTARATE AND AMMONIA IN RAT-LIVER MITOCHONDRIA. III. MALATE AS HYDROGEN DONOR.
    Biochimica et biophysica acta, 1963, Oct-01, Volume: 77

    Topics: Adenosine Triphosphate; Ammonia; Amobarbital; Anti-Bacterial Agents; Aspartic Acid; Dinitrophenols; Enzyme Inhibitors; Glutamates; Glutamic Acid; Hydrogen; Ketoglutaric Acids; Liver; Malates; Mitochondria; Mitochondria, Liver; NAD; Oligomycins; Pharmacology; Rats; Research

1963
THE OXIDATION OF L-MALATE BY PSEUDOMONAS SP.
    The Biochemical journal, 1963, Volume: 89

    Topics: Amobarbital; Carbohydrate Metabolism; Carbon Isotopes; Cyanides; Electrons; Indophenol; Malates; Microscopy; Microscopy, Electron; NAD; Oxidation-Reduction; Oxidoreductases; Pharmacology; Phenazines; Polarography; Pseudomonas; Research; Spectrophotometry; Ultrasonics

1963
METABOLISM OF DICARBOXYLIC ACIDS IN ACETOBACTER XYLINUM.
    Journal of bacteriology, 1964, Volume: 87

    Topics: Acetates; Acetobacter; Dicarboxylic Acids; Fumarates; Gluconacetobacter xylinus; Israel; Keto Acids; Kinetics; Malates; Metabolism; NAD; NADP; Oxidation-Reduction; Research; Spectrophotometry; Succinates

1964
METABOLIC ACTIVITY IN COXIELLA BURNETII.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Acetates; Amino Acids; Carbohydrate Metabolism; Citric Acid Cycle; Coxiella; Coxiella burnetii; Fumarates; Glutamates; Glutamic Acid; Keto Acids; Ketoglutaric Acids; Malates; NAD; Oxaloacetates; Pyruvates; Research; Serine; Succinates

1964
PRELIMINARY ENZYMATIC EVENTS IN ASPARAGINE-DEPENDENT DENITRIFICATION BY PSEUDOMONAS PERFECTOMARINUS.
    Journal of bacteriology, 1965, Volume: 89

    Topics: Asparagine; Denitrification; Malates; Metabolism; NAD; NADP; Pseudomonas; Pseudomonas stutzeri; Research

1965
MITOCHONDRIAL PYRIDINE NUCLEOTIDES IN THE OXIDATION OF ISOCITRATE AND MALATE.
    Nature, 1965, Feb-13, Volume: 205

    Topics: Citrates; Isocitrates; Liver; Malates; Metabolism; Mitochondria; NAD; NADP; Nucleotides; Oxidation-Reduction; Pyridines; Rats; Research

1965
PROPERTIES OF HUMAN SERUM MALATE DEHYDROGENASE (L-MALATE: NAD-OXIDOREDUCTASE).
    Indian journal of experimental biology, 1965, Volume: 3

    Topics: Blood; Humans; Malate Dehydrogenase; Malates; NAD; Oxaloacetates; Oxidoreductases

1965
CONTROL OF GLUTAMATE OXIDATION IN BRAIN AND LIVER MITOCHONDRIAL SYSTEMS.
    The Biochemical journal, 1965, Volume: 95

    Topics: Adenine Nucleotides; Amino Acids; Aspartate Aminotransferases; Brain; Brain Chemistry; Citric Acid Cycle; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Liver; Malates; Malonates; Mitochondria; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Pharmacology; Rats; Research

1965
THE OXIDATION OF GLUTAMATE BY RAT-LIVER MITOCHONDRIA.
    The Biochemical journal, 1965, Volume: 95

    Topics: Amino Acids; Arsenicals; Chromatography; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Liver; Malates; Malonates; Mitochondria; Mitochondria, Liver; NAD; Oxaloacetates; Oxidation-Reduction; Pharmacology; Pyruvates; Rats; Research; Succinates; Sulfinic Acids

1965
THE EFFECT OF DISULPHIDES ON MITOCHONDRIAL OXIDATIONS.
    The Biochemical journal, 1965, Volume: 95

    Topics: Antimetabolites; Citrates; Coenzyme A; Cystamine; Cystine; Glutathione; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Isocitrate Dehydrogenase; Ketoglutaric Acids; Malate Dehydrogenase; Malates; Mercaptoethanol; Mitochondria; NAD; Oxidation-Reduction; Oxidoreductases; Pharmacology; Research; Sulfides

1965
[Histochemical studies on succinic and malic acid dehydrogenases and DPN and TPN diaphorases in experimental myocardial infarction].
    Biulleten' eksperimental'noi biologii i meditsiny, 1962, Volume: 53

    Topics: Electron Transport Complex II; Lactate Dehydrogenases; Malates; Myocardial Infarction; NAD; NADPH Dehydrogenase; Oxidoreductases; Succinate Dehydrogenase

1962
Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules.
    American journal of physiology. Renal physiology, 2004, Volume: 286, Issue:4

    Topics: Acute Kidney Injury; Animals; Citric Acid Cycle; Cytosol; Electron Transport Complex I; Energy Metabolism; Female; Hypoxia; Ketoglutaric Acids; Kidney Tubules, Proximal; Malates; Mitochondria; NAD; Rabbits; Reperfusion Injury; Rotenone; Uncoupling Agents

2004
Isolated durum wheat and potato cell mitochondria oxidize externally added NADH mostly via the malate/oxaloacetate shuttle with a rate that depends on the carrier-mediated transport.
    Plant physiology, 2003, Volume: 133, Issue:4

    Topics: Biological Transport; Intracellular Membranes; Kinetics; Malate Dehydrogenase; Malates; Mitochondria; NAD; NADP; Oxaloacetic Acid; Oxidation-Reduction; Solanum tuberosum; Triticum

2003
Oxidation and reduction of pyridine nucleotides in alamethicin-permeabilized plant mitochondria.
    The Biochemical journal, 2004, May-15, Volume: 380, Issue:Pt 1

    Topics: Alamethicin; Cell Membrane Permeability; Dicarboxylic Acids; Electron Transport; Electron Transport Complex III; Electron Transport Complex IV; Intracellular Membranes; Malates; Mitochondria; NAD; NADH Dehydrogenase; NADP; NADPH Dehydrogenase; Osmotic Pressure; Oxidation-Reduction; Oxygen Consumption; Pisum sativum; Plant Leaves; Rotenone; Solanum tuberosum; Substrate Specificity

2004
Dual functional roles of ATP in the human mitochondrial malic enzyme.
    Biochemistry, 2004, Jun-15, Volume: 43, Issue:23

    Topics: Adenosine Triphosphate; Binding Sites; Dimerization; Humans; Kinetics; Malate Dehydrogenase; Malates; Mitochondria; Mitochondrial Proteins; Models, Molecular; Mutation; NAD; Protein Structure, Quaternary

2004
A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenase.
    The Journal of biological chemistry, 2004, Oct-08, Volume: 279, Issue:41

    Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Brain; Cell Line; Cyclic N-Oxides; Dose-Response Relationship, Drug; Glutamate Dehydrogenase; Glutamic Acid; Humans; Kinetics; Malates; Membrane Potentials; Microscopy, Confocal; Mitochondria; NAD; Neurons; Oxygen; PC12 Cells; Phenotype; Rats; Reactive Oxygen Species; Spin Labels; Succinic Acid; Sulfites; Time Factors

2004
Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I.
    Nature, 2004, Dec-02, Volume: 432, Issue:7017

    Topics: Aerobiosis; Amino Acid Sequence; Anaerobiosis; Animals; Electron Transport Complex I; Hydrogen; Malates; Mitochondria; Models, Biological; Molecular Sequence Data; NAD; NADH Dehydrogenase; Organelles; Phylogeny; Protein Subunits; Protozoan Proteins; Sequence Alignment; Symbiosis; Trichomonas vaginalis

2004
Crystal structure of the NAD biosynthetic enzyme quinolinate synthase.
    The Journal of biological chemistry, 2005, Jul-22, Volume: 280, Issue:29

    Topics: Archaeal Proteins; Binding Sites; Catalysis; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Malates; Multienzyme Complexes; NAD; Phosphates; Protein Conformation; Pyrococcus horikoshii; Structural Homology, Protein

2005
Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies.
    The Journal of physiology, 2005, Dec-15, Volume: 569, Issue:Pt 3

    Topics: Animals; Aspartic Acid; Computer Simulation; Cytosol; Energy Metabolism; Glycolysis; Humans; Ischemia; Kinetics; Lactic Acid; Malates; Mitochondria; Models, Biological; Myocardial Ischemia; Myocardium; NAD; Oxidation-Reduction; Oxygen Consumption

2005
The free NADH concentration is kept constant in plant mitochondria under different metabolic conditions.
    The Plant cell, 2006, Volume: 18, Issue:3

    Topics: Homeostasis; Ligands; Malates; Mitochondria; Models, Biological; NAD; Oxidation-Reduction; Solanum tuberosum; Spectrometry, Fluorescence

2006
YtsJ has the major physiological role of the four paralogous malic enzyme isoforms in Bacillus subtilis.
    Journal of bacteriology, 2006, Volume: 188, Issue:13

    Topics: Bacillus subtilis; Bacterial Proteins; Culture Media; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glucose; Malate Dehydrogenase; Malates; Multigene Family; NAD; NADP

2006
A mathematical model of the mitochondrial NADH shuttles and anaplerosis in the pancreatic beta-cell.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:2

    Topics: Animals; Biological Transport; Citric Acid Cycle; Fatty Acids; Glycolysis; Insulin-Secreting Cells; Lipid Peroxidation; Malates; Mice; Mitochondria; Models, Biological; Models, Theoretical; NAD

2007
The importance of redox shuttles to pancreatic beta-cell energy metabolism and function.
    Biochemical Society transactions, 2006, Volume: 34, Issue:Pt 5

    Topics: Animals; Aspartic Acid; Cytosol; Energy Metabolism; Flavin-Adenine Dinucleotide; Glucose; Glycerophosphates; Insulin; Insulin Secretion; Insulin-Secreting Cells; Malates; Mitochondria; Models, Biological; NAD; Oxidation-Reduction

2006
Thermodynamics and kinetics of the glyoxylate cycle.
    Biochemistry, 2006, Dec-26, Volume: 45, Issue:51

    Topics: Acetyl Coenzyme A; Catalysis; Glyoxylates; Kinetics; Malates; Models, Chemical; NAD; Osmolar Concentration; Oxidation-Reduction; Software; Succinic Acid; Thermodynamics; Time Factors

2006
Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle.
    The Journal of biological chemistry, 2007, Mar-09, Volume: 282, Issue:10

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Brain; Calcium; Glutamic Acid; Kinetics; Malates; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Molecular Sequence Data; Muscle, Skeletal; NAD

2007
Characterization of malate dehydrogenase from the hyperthermophilic archaeon Pyrobaculum islandicum.
    Extremophiles : life under extreme conditions, 2007, Volume: 11, Issue:5

    Topics: Citric Acid Cycle; Hydrogen-Ion Concentration; Kinetics; Malate Dehydrogenase; Malates; Molecular Weight; NAD; NADP; Oxaloacetic Acid; Phylogeny; Protein Conformation; Protein Subunits; Pyrobaculum; Recombinant Proteins; Sequence Analysis, Protein; Substrate Specificity; Temperature

2007
High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates.
    The Biochemical journal, 2008, Jan-15, Volume: 409, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Electron Transport Complex I; Electron Transport Complex II; Glutamic Acid; Malates; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle, Skeletal; NAD; Oxaloacetic Acid; Succinic Acid; Superoxides

2008
Multiple roles of arginine 181 in binding and catalysis in the NAD-malic enzyme from Ascaris suum.
    Biochemistry, 2007, Dec-18, Volume: 46, Issue:50

    Topics: Animals; Arginine; Ascaris suum; Binding Sites; Catalysis; Helminth Proteins; Humans; Hydrogen-Ion Concentration; Kinetics; Malate Dehydrogenase; Malates; NAD; NADP; Oxaloacetic Acid; Oxidation-Reduction; Protein Structure, Secondary

2007
Arabidopsis NAD-malic enzyme functions as a homodimer and heterodimer and has a major impact on nocturnal metabolism.
    Plant physiology, 2008, Volume: 146, Issue:4

    Topics: Amino Acids; Arabidopsis; Base Sequence; Carbohydrate Metabolism; Darkness; Dimerization; DNA Primers; Genes, Plant; Malates; NAD

2008
Reverse reaction of malic enzyme for HCO3- fixation into pyruvic acid to synthesize L-malic acid with enzymatic coenzyme regeneration.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:5

    Topics: Alginates; Carbon Dioxide; Glucosephosphate Dehydrogenase; Glucuronic Acid; Hexuronic Acids; Malate Dehydrogenase; Malates; NAD; Oxidation-Reduction; Pseudomonas; Pyruvic Acid

2008
Plant inner membrane anion channel (PIMAC) function in plant mitochondria.
    Plant & cell physiology, 2008, Volume: 49, Issue:7

    Topics: Adenosine Triphosphate; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Fatty Acids; Helianthus; Hydrogen Peroxide; Hydrogen-Ion Concentration; Ion Channels; Linoleic Acid; Malates; Membrane Potential, Mitochondrial; Mersalyl; Mitochondria; Mitochondrial Membranes; Mitochondrial Swelling; NAD; Osmosis; Propranolol; Solutions; Succinic Acid; Superoxides; Triticum

2008
Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver.
    Biogerontology, 2009, Volume: 10, Issue:4

    Topics: Age Factors; Aging; Aldehyde Reductase; Animals; Caloric Restriction; Fructose; Glucose; L-Iditol 2-Dehydrogenase; Lactic Acid; Liver; Malates; Male; Mice; Mice, Inbred C57BL; NAD; NADP; Oxidation-Reduction; Pyruvic Acid; Sorbitol

2009
Calcium signaling in brain mitochondria: interplay of malate aspartate NADH shuttle and calcium uniporter/mitochondrial dehydrogenase pathways.
    The Journal of biological chemistry, 2009, Mar-13, Volume: 284, Issue:11

    Topics: Animals; Aspartic Acid; Brain; Calcium; Calcium Channels; Calcium Signaling; Cytosol; Ketoglutaric Acids; Malates; Mice; Mitochondria, Heart; Mitochondrial Proteins; NAD; Organic Anion Transporters

2009
Production of L-malic acid with fixation of HCO3(-) by malic enzyme-catalyzed reaction based on regeneration of coenzyme on electrode modified by layer-by-layer self-assembly method.
    Journal of bioscience and bioengineering, 2009, Volume: 107, Issue:1

    Topics: Adsorption; Alginates; Bicarbonates; Buffers; Carbon Dioxide; Catalysis; Cations; Dihydrolipoamide Dehydrogenase; Electrochemistry; Electrodes; Glucuronic Acid; Hexuronic Acids; Malates; NAD; Polymers; Regeneration; Time Factors

2009
Purification, properties, and kinetic studies of cytoplasmic malate dehydrogenase from Taenia solium cysticerci.
    Parasitology research, 2009, Volume: 105, Issue:1

    Topics: Animals; Arsenates; Chemical Fractionation; Chromatography, Affinity; Chromatography, Ion Exchange; Coenzymes; Cytoplasm; Echinococcus granulosus; Enzyme Inhibitors; Helminth Proteins; Hydrogen-Ion Concentration; Isoelectric Point; Kinetics; Malate Dehydrogenase; Malates; Molecular Weight; NAD; Oxaloacetic Acid; Protein Subunits; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Taenia solium

2009
Synergistic effect of mediator-carbon nanotube composites for dehydrogenases and peroxidases based biosensors.
    Bioelectrochemistry (Amsterdam, Netherlands), 2009, Volume: 76, Issue:1-2

    Topics: Biosensing Techniques; Calibration; Catalysis; Electrochemistry; Enzymes, Immobilized; Ferrocyanides; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Malates; NAD; Nanocomposites; Nanotubes, Carbon; Oxazines; Oxidoreductases; Phenols

2009
Molecular cloning and characterization of a malic enzyme gene from the oleaginous yeast Lipomyces starkeyi.
    Molecular biotechnology, 2010, Volume: 45, Issue:2

    Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Humans; Kinetics; Lipomyces; Malate Dehydrogenase; Malates; Molecular Sequence Data; NAD; Phylogeny; Recombinant Proteins; Sequence Alignment

2010
Identification and biochemical characterization of a thermostable malate dehydrogenase from the mesophile Streptomyces coelicolor A3(2).
    Bioscience, biotechnology, and biochemistry, 2010, Volume: 74, Issue:11

    Topics: Catalysis; Enzyme Inhibitors; Enzyme Stability; Hot Temperature; Kinetics; Malate Dehydrogenase; Malates; NAD; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomyces coelicolor

2010
The functions of an apple cytosolic malate dehydrogenase gene in growth and tolerance to cold and salt stresses.
    Plant physiology and biochemistry : PPB, 2011, Volume: 49, Issue:3

    Topics: Cold Temperature; Cytosol; Gene Expression; Genes, Plant; Malate Dehydrogenase; Malates; Malus; NAD; Plant Proteins; Salt Tolerance; Sodium Chloride; Stress, Physiological

2011
Mitochondrial energy metabolism in young bamboo rhizomes from Bambusa oldhamii and Phyllostachys edulis during shooting stage.
    Plant physiology and biochemistry : PPB, 2011, Volume: 49, Issue:4

    Topics: Adaptation, Physiological; Adenosine Triphosphate; Bambusa; Cell Respiration; Electron Transport Complex I; Energy Metabolism; Ion Channels; Malates; Mitochondria; Mitochondrial Proteins; NAD; Oxidation-Reduction; Oxidoreductases; Plant Proteins; Poaceae; Potassium Channels; Rhizome; Seasons; Stress, Physiological; Succinic Acid; Superoxide Dismutase; Temperature; Uncoupling Protein 1

2011
Stimulatory effects of calcium on respiration and NAD(P)H synthesis in intact rat heart mitochondria utilizing physiological substrates cannot explain respiratory control in vivo.
    The Journal of biological chemistry, 2011, Sep-02, Volume: 286, Issue:35

    Topics: Adenosine Diphosphate; Animals; Calcium; Cell Respiration; Dose-Response Relationship, Drug; Ketoglutaric Acids; Malates; Mitochondria, Heart; NAD; NADP; Oxidative Phosphorylation; Oxygen; Phosphorylation; Protein Binding; Rats; Tricarboxylic Acids

2011
Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control.
    Malaria journal, 2011, Oct-26, Volume: 10

    Topics: Amino Acid Sequence; Animals; Anopheles; Cations, Divalent; Cell Line; Coenzymes; Enzyme Inhibitors; Fumarates; Kinetics; Magnesium; Malate Dehydrogenase; Malates; Manganese; Mass Spectrometry; Mitochondria; Models, Molecular; Molecular Sequence Data; NAD; NADP; Protein Conformation; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Succinic Acid

2011
Malate-aspartate shuttle and exogenous NADH/cytochrome c electron transport pathway as two independent cytosolic reducing equivalent transfer systems.
    Archives of biochemistry and biophysics, 2012, Feb-15, Volume: 518, Issue:2

    Topics: Animals; Apoptosis; Aspartic Acid; Biological Transport, Active; Cytochromes c; Electron Transport; Glutamate Dehydrogenase; Ketoglutaric Acids; Malates; Mitochondria, Liver; Mitochondrial Proteins; NAD; Oxidation-Reduction; Rats

2012
Influence of ethanol extract of Ginkgo biloba leaves on the isolated rat heart work and mitochondria functions.
    Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Fluorescence; Ginkgo biloba; Heart Rate; Hydrogen Peroxide; Malates; Male; Mitochondria, Heart; Myocardial Contraction; Myocardial Reperfusion Injury; NAD; Oxidation-Reduction; Plant Extracts; Plant Leaves; Pyruvic Acid; Rats; Rats, Wistar; Time Factors

2012
Mitochondrial respiration in ME-CAM, PEPCK-CAM, and C₃ succulents: comparative operation of the cytochrome, alternative, and rotenone-resistant pathways.
    Journal of experimental botany, 2012, Volume: 63, Issue:8

    Topics: Acetyl Coenzyme A; Carboxylic Acids; Cell Respiration; Cyanides; Cytochromes; Magnesium; Malate Dehydrogenase; Malates; Manganese; Metabolic Networks and Pathways; Mitochondria; NAD; NADP; Osmosis; Oxidation-Reduction; Oxygen Consumption; Phosphoenolpyruvate Carboxykinase (ATP); Plants; Pyruvates; Rotenone; Species Specificity; Succinic Acid

2012
Annotation and analysis of malic enzyme genes encoding for multiple isoforms in the fungus Mucor circinelloides CBS 277.49.
    Biotechnology letters, 2012, Volume: 34, Issue:5

    Topics: Amino Acid Motifs; Binding Sites; Coenzymes; Conserved Sequence; Genes, Fungal; Malate Dehydrogenase; Malates; Mucor; NAD; NADP; Phylogeny; Protein Binding; Protein Isoforms; Sequence Homology, Amino Acid

2012
The absence of alternative oxidase AOX1A results in altered response of photosynthetic carbon assimilation to increasing CO(2) in Arabidopsis thaliana.
    Plant & cell physiology, 2012, Volume: 53, Issue:9

    Topics: Arabidopsis; Biomass; Carbon; Carbon Dioxide; Cell Respiration; Malates; Mitochondrial Proteins; NAD; Oxaloacetic Acid; Oxidoreductases; Photosynthesis; Photosystem II Protein Complex; Plant Proteins; Plant Stomata; Ribulose-Bisphosphate Carboxylase

2012
Isolation of a high malic and low acetic acid-producing sake yeast Saccharomyces cerevisiae strain screened from respiratory inhibitor 2,4-dinitrophenol (DNP)-resistant strains.
    Journal of bioscience and bioengineering, 2014, Volume: 117, Issue:1

    Topics: 2,4-Dinitrophenol; Acetic Acid; Cytosol; Drug Resistance, Fungal; Ethanol; Malates; Mitochondria; Mutagenesis; NAD; Pyruvic Acid; Saccharomyces cerevisiae

2014
L-Malate dehydrogenase activity in the reductive arm of the incomplete citric acid cycle of Nitrosomonas europaea.
    Antonie van Leeuwenhoek, 2013, Volume: 104, Issue:5

    Topics: Citric Acid Cycle; Coenzymes; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Malate Dehydrogenase; Malates; NAD; NADP; Nitrosomonas europaea; Oxaloacetic Acid; Spectrophotometry

2013
Directed evolution of thermotolerant malic enzyme for improved malate production.
    Journal of bioscience and bioengineering, 2014, Volume: 117, Issue:2

    Topics: Biocatalysis; Directed Molecular Evolution; Enzyme Assays; Gene Library; Kinetics; Malate Dehydrogenase; Malates; NAD; NADP; Oxidation-Reduction; Point Mutation; Protein Engineering; Pyruvic Acid; Substrate Specificity; Thermococcus

2014
[Pharmacological correction of experimental mitochondrial dysfunction of brain stem neurons by rhytmocor and mildronate].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2013, Volume: 59, Issue:3

    Topics: Adenosine Diphosphate; Animals; Electron Transport Complex I; Glutamic Acid; Injections, Subcutaneous; Malates; Male; Methylhydrazines; Mitochondria; NAD; Neurons; Oxidation-Reduction; Oxidative Phosphorylation; Propafenone; Rats; Rats, Wistar; Rotenone; Succinic Acid

2013
Evolution of leaf anatomy and photosynthetic pathways in Portulacaceae.
    American journal of botany, 2013, Volume: 100, Issue:12

    Topics: Bayes Theorem; Biological Evolution; Carbon; Carbon Cycle; Carbon Isotopes; Malates; NAD; NADP; Photosynthesis; Phylogeny; Plant Leaves; Portulacaceae

2013
Isoflurane modulates cardiac mitochondrial bioenergetics by selectively attenuating respiratory complexes.
    Biochimica et biophysica acta, 2014, Volume: 1837, Issue:3

    Topics: Animals; Antimycin A; Electron Transport; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex III; Energy Metabolism; Isoflurane; Malates; Membrane Potential, Mitochondrial; Mitochondria, Heart; Models, Biological; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Wistar; Rotenone; Spectrometry, Fluorescence; Succinic Acid; Uncoupling Agents

2014
Identification of malic enzyme mutants depending on 1,2,3-triazole moiety-containing nicotinamide adenine dinucleotide analogs.
    Bioorganic & medicinal chemistry letters, 2014, Mar-01, Volume: 24, Issue:5

    Topics: Biocatalysis; Decarboxylation; Kinetics; Malate Dehydrogenase; Malates; Mutation; NAD; Oxidation-Reduction; Protein Binding; Triazoles

2014
Activity of the mitochondrial pyruvate dehydrogenase complex in plants is stimulated in the presence of malate.
    Mitochondrion, 2014, Volume: 19 Pt B

    Topics: Gene Expression Regulation, Enzymologic; Glycine; Hordeum; Kinetics; Malates; Mitochondria; NAD; Pisum sativum; Plant Leaves; Pyruvate Dehydrogenase Complex

2014
Metabolic regulation of phytoplasma malic enzyme and phosphotransacetylase supports the use of malate as an energy source in these plant pathogens.
    Microbiology (Reading, England), 2014, Volume: 160, Issue:Pt 12

    Topics: Acetyl Coenzyme A; Carbon Dioxide; Energy Metabolism; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Malate Dehydrogenase; Malates; NAD; NADP; Phosphate Acetyltransferase; Phytoplasma; Pyruvic Acid

2014
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
    Nature, 2014, Nov-20, Volume: 515, Issue:7527

    Topics: Adenosine Monophosphate; Animals; Aspartic Acid; Citric Acid Cycle; Disease Models, Animal; Electron Transport; Electron Transport Complex I; Fumarates; Ischemia; Malates; Male; Metabolomics; Mice; Mitochondria; Myocardial Infarction; Myocardium; Myocytes, Cardiac; NAD; Reactive Oxygen Species; Reperfusion Injury; Stroke; Succinate Dehydrogenase; Succinic Acid

2014
Allosteric substrate inhibition of Arabidopsis NAD-dependent malic enzyme 1 is released by fumarate.
    Phytochemistry, 2015, Volume: 111

    Topics: Allosteric Site; Arabidopsis; Fumarates; Kinetics; Malate Dehydrogenase; Malates; Mitochondria; Molecular Sequence Data; NAD

2015
Impaired cytosolic NADH shuttling and elevated UCP3 contribute to inefficient citric acid cycle flux support of postischemic cardiac work in diabetic hearts.
    Journal of molecular and cellular cardiology, 2015, Volume: 79

    Topics: Animals; Aspartic Acid; Carbon-13 Magnetic Resonance Spectroscopy; Carrier Proteins; Citric Acid Cycle; Cytosol; Diabetes Mellitus, Experimental; Hemodynamics; Ion Channels; Malates; Male; Mice, Inbred C57BL; Mitochondrial Proteins; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NAD; Oxidation-Reduction; Perfusion; PPAR alpha; Uncoupling Protein 2; Uncoupling Protein 3

2015
Krebs cycle metabolon formation: metabolite concentration gradient enhanced compartmentation of sequential enzymes.
    Chemical communications (Cambridge, England), 2015, Jan-25, Volume: 51, Issue:7

    Topics: Citric Acid Cycle; Diffusion; Enzymes; Malates; Microfluidic Analytical Techniques; Mitochondria; NAD

2015
Reassessment of the transhydrogenase/malate shunt pathway in Clostridium thermocellum ATCC 27405 through kinetic characterization of malic enzyme and malate dehydrogenase.
    Applied and environmental microbiology, 2015, Volume: 81, Issue:7

    Topics: Ammonium Compounds; Cellulose; Clostridium thermocellum; Coenzymes; Diphosphates; Ethanol; Gene Expression Regulation, Enzymologic; Kinetics; Malate Dehydrogenase; Malates; Metabolic Networks and Pathways; NAD; NADP; NADP Transhydrogenases; Oxaloacetic Acid

2015
SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth.
    The EMBO journal, 2015, Apr-15, Volume: 34, Issue:8

    Topics: Acetylation; Animals; Aspartate Aminotransferase, Mitochondrial; Aspartic Acid; Biological Transport; Carcinoma, Pancreatic Ductal; Cell Proliferation; Cells, Cultured; HEK293 Cells; Humans; Malates; Male; Mice; Mice, Inbred C57BL; Mice, Nude; NAD; Oxidation-Reduction; Pancreatic Neoplasms; Protein Processing, Post-Translational; Sirtuin 3

2015
Respiration and substrate transport rates as well as reactive oxygen species production distinguish mitochondria from brain and liver.
    BMC biochemistry, 2015, Sep-10, Volume: 16

    Topics: Animals; Aspartic Acid; Biological Transport; Brain; Cell Respiration; Dicarboxylic Acid Transporters; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Gene Expression Regulation; Glutamic Acid; Kinetics; Liver; Malates; Membrane Potential, Mitochondrial; Mice; Mitochondria, Liver; NAD; Organ Specificity; Reactive Oxygen Species; Succinic Acid

2015
Oxaloacetate enhances neuronal cell bioenergetic fluxes and infrastructure.
    Journal of neurochemistry, 2016, Volume: 137, Issue:1

    Topics: Adenosine Triphosphate; Cell Line; Cell Line, Tumor; Cytosol; Energy Metabolism; Glucose; Glycolysis; Humans; Malate Dehydrogenase; Malates; Mitochondria; NAD; Neuroblastoma; Neurons; Oxaloacetic Acid; Oxygen Consumption; Pyruvic Acid; RNA, Messenger

2016
Reactive oxygen species production in cardiac mitochondria after complex I inhibition: Modulation by substrate-dependent regulation of the NADH/NAD(+) ratio.
    Free radical biology & medicine, 2016, Volume: 96

    Topics: Animals; Aspartate Aminotransferases; Coenzyme A; Electron Transport Complex I; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Malate Dehydrogenase; Malates; Mitochondria, Heart; NAD; Oxygen Consumption; Pyridines; Rabbits; Reactive Oxygen Species; Rotenone; Substrate Specificity

2016
Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion.
    Oncotarget, 2016, Aug-02, Volume: 7, Issue:31

    Topics: Action Potentials; Adenosine Triphosphate; Aldehyde Dehydrogenase; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytosol; Female; Gossypol; Humans; Lung Neoplasms; Malates; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; NAD; NADP; Neoplasm Transplantation; Oxidative Phosphorylation; Oxidoreductases Acting on CH-NH Group Donors; Phenformin; RNA, Small Interfering

2016
Metabolic engineering of Escherichia coli W3110 to produce L-malate.
    Biotechnology and bioengineering, 2017, Volume: 114, Issue:3

    Topics: Bacterial Proteins; Bioreactors; Escherichia coli; Gene Deletion; Malate Dehydrogenase; Malates; Metabolic Engineering; NAD; Pyruvic Acid; Recombinant Proteins

2017
Mitochondrial remodeling in the liver following chronic alcohol feeding to rats.
    Free radical biology & medicine, 2017, Volume: 102

    Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Energy Metabolism; Ethanol; Humans; Malates; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Rats

2017
Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC.
    Cell death & disease, 2016, 12-08, Volume: 7, Issue:12

    Topics: A549 Cells; Adenosine Triphosphate; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Death; Cell Proliferation; Cell Survival; Cytosol; Drug Synergism; Fluorouracil; Gene Knockdown Techniques; Glutamic Acid; Glutaminase; Glutamine; Lung Neoplasms; Malates; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; NAD; Oxidation-Reduction; Sulfides; Thiadiazoles; Thymidylate Synthase; Xenograft Model Antitumor Assays

2016
Specific Arabidopsis thaliana malic enzyme isoforms can provide anaplerotic pyruvate carboxylation function in Saccharomyces cerevisiae.
    The FEBS journal, 2017, Volume: 284, Issue:4

    Topics: Arabidopsis; Arabidopsis Proteins; Carbon Dioxide; Cloning, Molecular; Gene Expression; Genetic Complementation Test; Genetic Engineering; Glucose; Isoenzymes; Malate Dehydrogenase (NADP+); Malates; NAD; NADP; Plant Leaves; Pyruvic Acid; Recombinant Proteins; Saccharomyces cerevisiae; Transformation, Genetic; Transgenes

2017
Creation of a formate: malate oxidoreductase by fusion of dehydrogenase enzymes with PEGylated cofactor swing arms.
    Protein engineering, design & selection : PEDS, 2018, 04-01, Volume: 31, Issue:4

    Topics: Biocatalysis; Formates; Malates; Models, Molecular; NAD; Oxidoreductases; Polyethylene Glycols; Protein Conformation; Protein Engineering; Recombinant Fusion Proteins

2018
Conformational changes on substrate binding revealed by structures of Methylobacterium extorquens malate dehydrogenase.
    Acta crystallographica. Section F, Structural biology communications, 2018, Oct-01, Volume: 74, Issue:Pt 10

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Apoenzymes; Bacterial Proteins; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Genetic Vectors; Hydrogen Bonding; Kinetics; Malate Dehydrogenase; Malates; Methylobacterium extorquens; Models, Molecular; NAD; Oxaloacetic Acid; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Multimerization; Protons; Recombinant Proteins; Substrate Specificity

2018
Structure of glyoxysomal malate dehydrogenase (MDH3) from Saccharomyces cerevisiae.
    Acta crystallographica. Section F, Structural biology communications, 2018, Oct-01, Volume: 74, Issue:Pt 10

    Topics: Amino Acid Sequence; Apoenzymes; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Genetic Vectors; Glyoxysomes; Isoenzymes; Malate Dehydrogenase; Malates; Models, Molecular; NAD; Oxaloacetic Acid; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity

2018
Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD
    Cell death & disease, 2018, 11-14, Volume: 9, Issue:11

    Topics: Adenosine Triphosphate; Aspartic Acid; Cell Death; Culture Media; Electron Transport Complex I; Fibroblasts; Galactose; Gene Expression; Glycolysis; Humans; Ketoglutaric Acids; Leigh Disease; Malates; Mitochondria; Mitochondrial Diseases; Mutation; NAD; NADH Dehydrogenase; Oxaloacetic Acid; Primary Cell Culture; Pyruvic Acid; Skin

2018
Exogenous γ-aminobutyric acid treatment improves the cold tolerance of zucchini fruit during postharvest storage.
    Plant physiology and biochemistry : PPB, 2019, Volume: 136

    Topics: 4-Aminobutyrate Transaminase; Adenosine Triphosphate; Alanine; Amine Oxidase (Copper-Containing); Cell Death; Cold Temperature; Cucurbita; Food Storage; Fruit; Fumarates; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Malates; NAD; Proline; Putrescine

2019
Regulation of mitochondrial NAD pool via NAD
    Science China. Life sciences, 2019, Volume: 62, Issue:8

    Topics: Arabidopsis; Arabidopsis Proteins; Biological Transport; Chloroplasts; Cloning, Molecular; Fatty Acid Synthases; Gene Expression Regulation, Plant; Homeostasis; Malates; Mitochondria; Mitochondrial Proteins; Mutation; NAD; Nucleotide Transport Proteins; Reactive Oxygen Species

2019
Malate-aspartate shuttle promotes l-lactate oxidation in mitochondria.
    Journal of cellular physiology, 2020, Volume: 235, Issue:3

    Topics: Aspartic Acid; Colonic Neoplasms; HCT116 Cells; Homeostasis; Humans; Lactic Acid; Malates; Mitochondria; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Warburg Effect, Oncologic

2020
A new water-soluble bacterial NADH: fumarate oxidoreductase.
    FEMS microbiology letters, 2020, 11-11, Volume: 367, Issue:20

    Topics: Anaerobiosis; Enzyme Activation; Fumarates; Klebsiella pneumoniae; Malates; NAD; NADH Dehydrogenase; Water

2020
Comparative Study of Functional Changes in Heart Mitochondria in Two Modes of Epinephrine Exposure Modeling Myocardial Injury in Rats.
    Bulletin of experimental biology and medicine, 2021, Volume: 171, Issue:6

    Topics: Adenosine Triphosphate; Animals; Calcium; Cardiomyopathies; Cations, Divalent; Disease Models, Animal; Electron Transport Complex II; Epinephrine; Glutamic Acid; Malates; Male; Mitochondria, Heart; Myocardium; Myocytes, Cardiac; NAD; Oxidative Phosphorylation; Rats; Rats, Wistar; Succinic Acid

2021
Malate induces stomatal closure via a receptor-like kinase GHR1- and reactive oxygen species-dependent pathway in Arabidopsis thaliana.
    Bioscience, biotechnology, and biochemistry, 2022, Sep-23, Volume: 86, Issue:10

    Topics: Abscisic Acid; Arabidopsis; Arabidopsis Proteins; Calcium; Carbon Dioxide; Malates; NAD; Niflumic Acid; Oxidoreductases; Peroxidases; Phosphates; Plant Growth Regulators; Plant Stomata; Protein Kinase Inhibitors; Protein Kinases; Reactive Oxygen Species; Verapamil

2022
Disruption of mitochondrial functions involving mitochondrial permeability transition pore opening caused by maleic acid in rat kidney.
    Journal of bioenergetics and biomembranes, 2022, Volume: 54, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Glutamic Acid; HEK293 Cells; Humans; Kidney; Kidney Failure, Chronic; Malates; Maleates; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NAD; Permeability; Propidium; Propionic Acidemia; Rats; Rats, Wistar

2022
A functionally uncharacterized type-2 malate/L-lactate dehydrogenase family protein from Thermus thermophilus HB8 catalyzes stereospecific reduction of 2-keto-3-deoxy-D-gluconate.
    Extremophiles : life under extreme conditions, 2022, Nov-23, Volume: 26, Issue:3

    Topics: L-Lactate Dehydrogenase; Lactic Acid; Malates; NAD; Phylogeny; Thermus thermophilus

2022
Metabolic engineering of the acid-tolerant yeast Pichia kudriavzevii for efficient L-malic acid production at low pH.
    Metabolic engineering, 2023, Volume: 75

    Topics: Escherichia coli; Fermentation; Hydrogen-Ion Concentration; Metabolic Engineering; NAD; Pyruvates; Saccharomyces cerevisiae; Salts

2023
The Roles of Nicotinamide Adenine Dinucleotide Phosphate Reoxidation and Ammonium Assimilation in the Secretion of Amino Acids as Byproducts of Clostridium thermocellum.
    Applied and environmental microbiology, 2023, 01-31, Volume: 89, Issue:1

    Topics: Amino Acids; Ammonium Compounds; Clostridium thermocellum; Ethanol; Ferredoxins; Malates; NAD; NADP; Oxidation-Reduction; Pyruvates

2023
Analysis of organic acid metabolism reveals citric acid and malic acid play major roles in determining acid quality during the development of kiwifruit (Actinidia eriantha).
    Journal of the science of food and agriculture, 2023, Volume: 103, Issue:12

    Topics: Acids; Actinidia; Citric Acid; Fruit; NAD; Quinic Acid

2023
Fumarase activity in NAD-dependent malic enzyme, MaeA, from Escherichia coli.
    Biochemical and biophysical research communications, 2023, 10-20, Volume: 678

    Topics: Escherichia coli; Fumarate Hydratase; Fumarates; Humans; Malates; NAD; NADP; Pyruvic Acid

2023