Page last updated: 2024-08-17

nad and guanine

nad has been researched along with guanine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19909 (36.00)18.7374
1990's4 (16.00)18.2507
2000's6 (24.00)29.6817
2010's3 (12.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Anderson, FS; Murphy, RC1
Cukier, M; de Recondo, ME; Guerrero, G; Moreno, SM; Recondo, EF1
King, CR; Maguire, MH; Slegel, P; Szabo, I1
Bothe, D; Kappus, H; Mahmutoglu, I1
Fujioka, M; Nakatani, Y1
Bootsma, J; Groen, A; Nusse, BJ; Wolthers, BG1
Holmes, EW; Kelley, WN; Pehlke, DM1
Ballio, A; Kulaev, I; Moret, V; Russi, S1
Blair, DG1
Iwainsky, H; Reutgen, H1
Aschhoff, HJ; Kersten, H; Schachner, E1
Kawanishi, S; Ohkuma, Y1
Dimitriadis, EK; Joe, YA; Lee, YB; Park, MH; Wolff, EC1
Goodsell, DS; Morris, GM; Olson, AJ; Zhao, S1
Kawanishi, S; Murata, M1
Hirakawa, K; Hiraku, Y; Kawanishi, S; Murata, M; Oikawa, S; Seike, K1
Arris, CA; Calvert, HA; Canan-Koch, S; Curtin, NJ; Durkacz, BW; Hostomsky, Z; Kyle, S; Newell, DR; Wang, LZ; Webber, SE; Yiakouvaki, A1
Higuchi, I; Umehara, F; Usuki, F; Yasutake, A1
Davies, DR; Park, MH; Umland, TC; Wolff, EC1
Avizonis, D; Bramoullé, A; Bridon, G; Chan, M; Gravel, M; Roulston, A; Shore, GC1
Ritacco, I; Russo, N; Sicilia, E1
Mandal, A; Mandal, S; Park, MH; Wolff, EC1
Ambrus-Aikelin, G; Imamura, S; Kimura, H; Kitazawa, S; Klein, MG; Kurasawa, O; Matsumoto, S; Morishita, D; Ogawa, K; Okaniwa, M; Ono, K; Saito, B; Tanaka, Y; Uchiyama, N; Yokota, A1
Heney, KA; Lidster, T; Lyons, B; Merrill, AR; Vatta, M1
Abramova, TV; Kurgina, TA; Kutuzov, MM; Lavrik, OI; Maltseva, EA; Nilov, DK; Poroikov, VV; Shcherbakova, TA; Shram, SI; Švedas, VK1

Other Studies

25 other study(ies) available for nad and guanine

ArticleYear
Isocratic separation of some purine nucleotide, nucleoside, and base metabolites from biological extracts by high-performance liquid chromatography.
    Journal of chromatography, 1976, Jun-23, Volume: 121, Issue:2

    Topics: Adenine Nucleotides; Animals; Blood Platelets; Caffeine; Cats; Chromatography, High Pressure Liquid; Erythrocytes; Guanine; Hypoxanthines; Inosine; Inosine Nucleotides; NAD; NADP; Nucleosides; Purine Nucleotides; Spleen; Theobromine

1976
Nucleotides in embryos in the stages of morula, gastrula, and neurula.
    Carbohydrate research, 1976, Volume: 47, Issue:2

    Topics: Adenosine Diphosphate; Animals; Bufo arenarum; Embryo, Nonmammalian; Female; Guanine; Guanine Nucleotides; Guanosine Triphosphate; Male; NAD; Nucleotides; Time Factors; Uracil Nucleotides

1976
Determination of concentrations of adenosine and other purines in human term placenta by reversed-phase high-performance liquid chromatography with photodiode-array detection: evidence for pathways of purine metabolism in the placenta.
    Journal of chromatography, 1992, Mar-27, Volume: 575, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Female; Guanine; Humans; NAD; NADP; Placenta; Pregnancy; Purines

1992
The role of reactive oxygen species in the antitumor activity of bleomycin.
    Free radical research communications, 1990, Volume: 11, Issue:4-5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Bleomycin; Cattle; Cell Nucleus; Chlorides; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Deoxyguanosine; DNA; DNA Damage; Ferric Compounds; Guanine; Hydroxylation; Liver; Microsomes, Liver; NAD; Oxidation-Reduction; Oxygen; Rats

1990
Saccharopine dehydrogenase. A kinetic study of coenzyme binding.
    The Journal of biological chemistry, 1974, Nov-10, Volume: 249, Issue:21

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Glyceric Acids; Guanine; Hypoxanthines; Kinetics; Lysine; Mathematics; NAD; NADP; Nucleoside Diphosphate Sugars; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Ribonucleotides; Ribose; Saccharomyces cerevisiae; Ultrafiltration

1974
Determination of serum guanase by means of a NADH-linked reaction.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 41

    Topics: Aminohydrolases; Glutamate Dehydrogenase; Guanine; Humans; Kinetics; Liver Diseases; Mathematics; Methods; NAD; Spectrophotometry, Ultraviolet; Xanthine Oxidase

1972
Human IMP dehydrogenase. Kinetics and regulatory properties.
    Biochimica et biophysica acta, 1974, Oct-17, Volume: 364, Issue:2

    Topics: Adenine; Adenosine; Carbon Radioisotopes; Cell Fractionation; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosol; Female; Guanine; Guanosine; Humans; Inosine Nucleotides; Ketone Oxidoreductases; Kinetics; Mercaptopurine; Mitochondria; NAD; Placenta; Pregnancy; Purine Nucleotides; Pyrimidine Nucleotides; Structure-Activity Relationship; Ultracentrifugation

1974
Nucleotides of microorganisms. XI. The occurrence of guanine propionate in Claviceps paspali Stevens and Hall.
    Biochimica et biophysica acta, 1966, Feb-28, Volume: 115, Issue:2

    Topics: Adenine Nucleotides; Ascomycota; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cytosine Nucleotides; Guanine; Guanine Nucleotides; In Vitro Techniques; NAD; NADP; Nucleosides; Propionates

1966
Acid-soluble metabolites of adenine-2-14C-adenine-8-14C in 2,6-diaminopurine-sensitive and 2,6-diaminopurine-resistant L strain mouse cells.
    Canadian journal of biochemistry, 1968, Volume: 46, Issue:3

    Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Guanine; Guanine Nucleotides; L Cells; Mice; NAD; NADP; Nucleosides; Perchlorates; Purines; Urea; Uric Acid; Xanthines

1968
[Studies on the endogenous metabolism of mycobacteria. I. On the separation of phosphorylated metabolites from the acid-soluble fraction].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1967, Volume: 22, Issue:10

    Topics: Adenine Nucleotides; Chromatography, Ion Exchange; Chromatography, Paper; Cytosine Nucleotides; Guanine; Guanine Nucleotides; Mycobacterium; NAD; NADP; Nucleosides; Nucleotides; Phosphorus Isotopes; Uracil Nucleotides

1967
Specific changes in lactate levels, lactate dehydrogenase patterns and cytochrome b559 in Dictyostelium discoideum caused by queuine.
    European journal of biochemistry, 1984, Mar-15, Volume: 139, Issue:3

    Topics: Cytochrome b Group; Dictyostelium; Guanine; Isoelectric Focusing; L-Lactate Dehydrogenase; Lactates; NAD; Photosystem II Protein Complex

1984
Oxidative DNA damage by a metabolite of carcinogenic and reproductive toxic nitrobenzene in the presence of NADH and Cu(II).
    Biochemical and biophysical research communications, 1999, Apr-13, Volume: 257, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Catalase; Cations; Cattle; Chelating Agents; Chromatography, High Pressure Liquid; Copper; Cytosine; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Guanine; Humans; Hydrogen Peroxide; Metals; Models, Chemical; NAD; Nitrobenzenes; Nitroso Compounds; Oxidation-Reduction; Piperidines; Thymine

1999
Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor.
    The Biochemical journal, 1999, May-15, Volume: 340 ( Pt 1)

    Topics: Cell Extracts; Chromatography, Affinity; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Hydrogen-Ion Concentration; Molecular Weight; NAD; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Binding; Protein Precursors; Protons; Recombinant Fusion Proteins; RNA-Binding Proteins; Sequence Analysis; Spermidine; Temperature; Thermodynamics; Ultracentrifugation

1999
Recognition templates for predicting adenylate-binding sites in proteins.
    Journal of molecular biology, 2001, Dec-14, Volume: 314, Issue:5

    Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Computational Biology; Computer Simulation; Consensus Sequence; Databases, Protein; Flavin-Adenine Dinucleotide; Guanine; Guanosine Monophosphate; Guanosine Triphosphate; Hydrogen Bonding; Ligands; Models, Molecular; NAD; Protein Binding; Protein Conformation; Protein Interaction Mapping; Proteins; Substrate Specificity; Thermodynamics

2001
Oxidation of 5'-site guanine at GG and GGG sequences induced by a metabolite of carcinogenic heterocyclic amine PhIP in the presence of Cu(II) and NADH.
    Carcinogenesis, 2002, Volume: 23, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Cattle; Copper; Deoxyguanosine; DNA; DNA Damage; Guanine; Imidazoles; NAD; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Spectrophotometry, Ultraviolet

2002
Oxidative DNA damage induced by benz[a]anthracene metabolites via redox cycles of quinone and unique non-quinone.
    Chemical research in toxicology, 2003, Volume: 16, Issue:11

    Topics: Animals; Benz(a)Anthracenes; Catalase; Copper; Deoxyadenosines; DNA Damage; DNA Fragmentation; Dose-Response Relationship, Drug; Genes, p16; Genes, ras; Guanine; Humans; NAD; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Phosphorus Radioisotopes; Polycyclic Aromatic Hydrocarbons; Quinones; Tumor Suppressor Protein p53

2003
Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-01, Volume: 10, Issue:3

    Topics: Adenine; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Azulenes; Base Pair Mismatch; Benzodiazepines; Cell Division; Cell Line, Tumor; Cisplatin; Dacarbazine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Genotype; Guanine; Humans; Models, Chemical; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Temozolomide

2004
Beneficial effects of mild lifelong dietary restriction on skeletal muscle: prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin.
    Acta neuropathologica, 2004, Volume: 108, Issue:1

    Topics: Aging; Animals; Catalase; Crystallins; Diet; Food Deprivation; Glutathione Peroxidase; Guanine; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Male; Mercury; Mitochondria, Muscle; Muscle, Skeletal; NAD; Rats; Rats, Wistar; Superoxide Dismutase; Tissue Distribution

2004
A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complex.
    The Journal of biological chemistry, 2004, Jul-02, Volume: 279, Issue:27

    Topics: Alkyl and Aryl Transferases; Amino Acid Motifs; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Dimerization; Electrons; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Hydrogen-Ion Concentration; Ions; Models, Molecular; NAD; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Binding; Protein Conformation; Protein Structure, Secondary; RNA-Binding Proteins; Spermidine; X-Ray Diffraction

2004
Synergy between the NAMPT inhibitor GMX1777(8) and pemetrexed in non-small cell lung cancer cells is mediated by PARP activation and enhanced NAD consumption.
    Cancer research, 2014, Nov-01, Volume: 74, Issue:21

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytokines; DNA Repair; Drug Synergism; Gene Expression Regulation, Neoplastic; Glutamates; Guanidines; Guanine; Humans; Mice; NAD; Nicotinamide Phosphoribosyltransferase; Pemetrexed; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Transcriptional Activation; Xenograft Model Antitumor Assays

2014
DFT Investigation of the Mechanism of Action of Organoiridium(III) Complexes As Anticancer Agents.
    Inorganic chemistry, 2015, Nov-16, Volume: 54, Issue:22

    Topics: Adenine; Antineoplastic Agents; Coordination Complexes; Glutathione; Guanine; Hydrolysis; Iridium; Models, Chemical; Models, Molecular; NAD; Oxidation-Reduction

2015
A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening.
    Amino acids, 2017, Volume: 49, Issue:11

    Topics: Biosynthetic Pathways; Enzyme Assays; Enzyme Inhibitors; Guanine; High-Throughput Screening Assays; Humans; Hydrogen-Ion Concentration; Kinetics; Luminescent Measurements; NAD; Oxidoreductases Acting on CH-NH Group Donors; Small Molecule Libraries; Spermidine; Substrate Specificity; Time Factors

2017
Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Allosteric Site; Crystallography, X-Ray; Drug Discovery; Enzyme Assays; Enzyme Inhibitors; Guanine; High-Throughput Screening Assays; Humans; Indoles; Molecular Structure; NAD; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Protein Conformation; Spermidine; Structure-Activity Relationship; Thiophenes

2020
Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from
    Toxins, 2021, 01-13, Volume: 13, Issue:1

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Bacterial Proteins; Bacterial Toxins; Catalytic Domain; Crystallography, X-Ray; DNA; DNA-Binding Proteins; Guanine; Kinetics; Molecular Dynamics Simulation; NAD; Protein Binding; Protein Conformation; RNA; Streptomyces; Structure-Activity Relationship

2021
Inhibitory Effects of 7-Methylguanine and Its Metabolite 8-Hydroxy-7-Methylguanine on Human Poly(ADP-Ribose) Polymerase 1.
    Biochemistry. Biokhimiia, 2022, Volume: 87, Issue:8

    Topics: Guanine; Humans; NAD; Nucleic Acids

2022