nad has been researched along with glutamine in 166 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 72 (43.37) | 18.7374 |
| 1990's | 23 (13.86) | 18.2507 |
| 2000's | 25 (15.06) | 29.6817 |
| 2010's | 27 (16.27) | 24.3611 |
| 2020's | 19 (11.45) | 2.80 |
| Authors | Studies |
|---|---|
| Lev, M; Milford, AF | 2 |
| Lea, PJ; Miflin, BJ | 2 |
| Cooper, AJ; Gross, M; Meister, A | 1 |
| Vinay, P | 1 |
| Matinian, KS; Umanskiĭ, SR | 1 |
| Hindfelt, B | 1 |
| Coudert, M; Lemal, J; Vandecasteele, JP | 1 |
| Kim, H; Patel, MS | 1 |
| Gerok, W; Häussinger, D; Lang, F; Morimoto, Y; Stoll, B | 1 |
| Butterworth, RF; Qureshi, IA; Ratnakumari, L | 1 |
| Collier, RJ; Reich, KA; Weinstein, BR; Wilson, BA | 1 |
| Bosron, WF; Edenberg, HJ; Ehrig, T; Hurley, TD | 1 |
| Micheli, V; Simmonds, HA | 1 |
| Matsuno, T | 1 |
| Blachier, F; Malaisse, WJ; Sener, A | 1 |
| Eizirik, DL; Malaisse, WJ; Sandler, S; Sener, A | 1 |
| Chin, NW; Hitti, IF; Lanks, KW | 1 |
| Márquez, FJ; Medina, MA; Núñez de Castro, I; Pérez-Rodríguez, J; Quesada, AR; Sánchez-Jiménez, F | 1 |
| Capito, K; Hedeskov, CJ; Thams, P | 1 |
| Atkinson, T; Barstow, DA; Chia, WN; Clarke, AR; Holbrook, JJ; Wigley, DB | 1 |
| Curi, R; Newsholme, EA; Newsholme, P | 1 |
| Brown, CM; Burn, VJ; Johnson, B | 1 |
| Dunn, SD; Klucas, RV | 1 |
| Dougall, DK | 1 |
| Fowler, MW; Jessup, W; Sarkissian, GS | 1 |
| Dubois, EL; Grenson, M | 1 |
| Al-Gharawi, A; Moore, D | 1 |
| Buniatian, GKh | 1 |
| Bray, D; Kapoor, M | 1 |
| Koshland, DE; Teipel, J | 1 |
| Bray, DF; Kapoor, M; Ward, GW | 1 |
| Ababei, L; Filip, M | 1 |
| Brosnan, JT; Krebs, HA; Williamson, DH | 1 |
| Hersh, LB; Srere, PA | 1 |
| Brosnan, JT; Hems, DA | 1 |
| Cooney, D; Davis, R; Van Atta, G | 1 |
| Buttery, PJ; Rowsell, EV | 1 |
| Nahorski, SR | 1 |
| Preuss, HG; Weiss, FR | 1 |
| Lemieux, G; Lussier, Y; Martin, P; Plante, GE; Robitaille, P; Vinay, P | 1 |
| Barnes, EM; Kaback, HR; Konings, WN | 1 |
| Häkkinen, HM; Kulonen, E | 1 |
| Dietrich, LS; Yi, CK | 1 |
| Ainslie, GR; Neet, KE; Shill, JP | 1 |
| Buchanan, JM | 1 |
| Even, HL; Larimore, F; Roon, RJ | 1 |
| Brand, MD; Chappell, JB | 1 |
| Dennen, DW; Niederpruem, DJ | 1 |
| Chamalaun, RA; Tager, JM | 1 |
| Kajinami, S; Smith, EC | 1 |
| Langer, BW; Smith, WJ; Theodorides, VJ | 1 |
| Ferguson, AR; Sims, AP | 1 |
| Elmerich, C | 1 |
| Araújo, EF; Caldas, RA; Felix, CR; Roitman, I | 1 |
| Makarewicz, W; Swierczyński, J | 1 |
| Lehninger, AL; Moreadith, RW | 1 |
| Magasanik, B; Mitchell, AP | 1 |
| Hummelt, G; Mora, J | 2 |
| Costell, M; Grisolía, S; O'Connor, JE | 1 |
| Tischler, ME | 1 |
| Christophe, J; Hutton, JC; Malaisse, WJ; Malaisse-Legae, F; Sener, A | 1 |
| Hong, J; Hunt, AG | 1 |
| Garcia-Morales, P; Malaisse, WJ; Malaisse-Lagae, F; Sener, A; Valverde, I | 1 |
| Malaisse, WJ; Malaisse-Lagae, F; Sener, A | 1 |
| Bier, DM; Hellerström, C; Malaisse, WJ; Malaisse-Lagae, F; Matthews, DE; Sener, A; Welsh, M | 1 |
| Goldstein, L; McLaughlin, PM; Perlman, DF; Solomon, RJ; Taylor, MA | 1 |
| Ledig, M; M'Paria, JR; Mandel, P | 1 |
| Lin, ZP; Nissim, I; States, B; Yudkoff, M | 1 |
| Nordlund, S; Norén, A | 1 |
| Bachelard, HS; Badar-Goffer, RS; Ben-Yoseph, O; Morris, PG | 1 |
| Friedman, S; Gao, JP; Lanks, KW | 1 |
| Cameron, LE; LéJohn, HB; Rennie, SL; Yang, B | 1 |
| Cullen, G; Dolphin, AC; Fazeli, MS; Huston, E; Pearson, H; Sweeney, MI | 1 |
| Crabb, DW; Sidhu, R | 1 |
| Filov, VA; Reztsova, VV | 1 |
| Kimura, RE | 1 |
| Sligar, SG; Yeom, H | 1 |
| den Camp, HJ; der Drift, CV; Dijkerman, R; Ledeboer, J; Verhappen, AB; Vogels, GD | 1 |
| Hurley, TD; Ni, L; Sheikh, S; Weiner, H | 1 |
| Akiyama, DS; Niihara, Y; Tanaka, KR; Zerez, CR | 2 |
| Brambilla, L; Cantoni, O; Clementi, E; Guidarelli, A; Sciorati, C | 1 |
| Araki, T; Masuyama, Y; Morita, Y; Sakai, T | 1 |
| LeBrun, LA; Plapp, BV | 1 |
| Dodzin, ME; Vinogradova, KA | 1 |
| Chapman, BE; Doverskog, M; Häggström, L; Jacobsson, U; Kuchel, PW | 1 |
| Börger, J; Brabant, G; Lange, S; Schöfl, C; von zur Mühlen, A | 1 |
| Adams, MJ; Ciccone, T; Cosgrove, MS; Davino, MH; Fairbairn, L; Levy, HR; Lin, Y; Vought, V | 1 |
| Akimoto, LS; Bazotte, RB; Lopes, G; Pedrinho, SR | 1 |
| Ballou, DP; Ludwig, ML; Matthews, RG; Trimmer, EE | 1 |
| Bouzier-Sore, AK; Canioni, P; Merle, M | 1 |
| Esposito, C; Francese, S; Marino, G; Orru, S; Ruoppolo, M; Vitagliano, L | 1 |
| Cho, S; Izaguirre, G; MacKerell, A; Pietruszko, R | 1 |
| Pérez-Pinzón, MA; Veauvy, CM; Walsh, PJ; Wang, Y | 1 |
| Cotton, NP; Jackson, JB; Quirk, PG; van Boxel, GI; White, SA | 1 |
| Bieganowski, P; Brenner, C | 1 |
| HOLZER, H; SCHNEIDER, S | 1 |
| CONTRERAS, E; CROXATTO, R; HUIDOBRO, F | 1 |
| ALLAN, PW; TOMISEK, AJ | 1 |
| POMEROY, LR; ROACH, MK; SIEGEL, FL | 1 |
| DIETRICH, LS; FULLER, L | 1 |
| AYLING, JE; BALTIMORE, BG; KUN, E | 1 |
| HERSCOVICS, A; JOHNSTONE, RM | 1 |
| Demuth, HU; Hoffmann, T; Ludwig, HH; Manhart, S; Schilling, S; Wasternack, C | 1 |
| LeBrun, LA; Park, DH; Plapp, BV; Ramaswamy, S | 1 |
| Ali, TH; Elzainy, TA | 1 |
| Holden, HM; Thoden, JB | 1 |
| Boswell, EL; Pletnev, V; Scaccia, LA; Thomas, JL; Umland, TC | 1 |
| Gadre, R; Gupta, P | 1 |
| Gerdes, SY; Kurnasov, OV; Osterman, AL; Overbeek, R; Polanuyer, B; Shatalin, K; Sloutsky, R; Vonstein, V | 1 |
| Cho, H; Gao, D; Hamza, A; Huang, L; Tai, HH; Zhan, CG | 1 |
| Bieganowski, P; Brenner, C; Seidle, HF; Wojcik, M | 1 |
| Alt, FW; Blander, G; Christodoulou, DC; Fahie, K; Guarente, L; Haigis, KM; Haigis, MC; Karow, M; Mostoslavsky, R; Murphy, AJ; Prolla, TA; Valenzuela, DM; Weindruch, R; Wolberger, C; Yancopoulos, GD | 1 |
| Howarth, C; Hyder, F; Riera, JJ; Schousboe, A; Waagepetersen, HS | 1 |
| Belevich, G; Bloch, DA; Euro, L; Verkhovskaya, M; Verkhovsky, MI; Wikström, M | 1 |
| Gerratana, B; LaRonde-LeBlanc, N; Resto, M | 1 |
| Gerratana, B; Resto, M; Yaffe, J | 1 |
| Andi, B; Bobyk, KD; Cook, PF; Ekanayake, DK; West, AH | 1 |
| Barkhouse, DA; Castegna, A; Curtis, MT; Fabis-Pedrini, MJ; Hooper, DC; Kean, RB; Palmieri, F; Palmieri, L; Porcelli, V; Spera, I | 1 |
| Adam, J; Chaneton, B; Deberardinis, RJ; Folger, O; Frezza, C; Gottlieb, E; Hedley, A; Jerby, L; Kalna, G; MacKenzie, ED; Micaroni, M; Pollard, PJ; Rajagopalan, KN; Ruppin, E; Shlomi, T; Tomlinson, IP; Watson, DG; Zheng, L | 1 |
| Vander Heiden, MG | 1 |
| Galeffi, F; Turner, DA | 1 |
| Bell, EL; Fendt, SM; Guarente, L; Keibler, MA; Mayers, JR; Olenchock, BA; Stephanopoulos, G; Vander Heiden, MG; Vokes, NI; Wasylenko, TM | 1 |
| Guarente, L | 1 |
| Bobrovnikova-Marjon, E; Hurov, JB | 1 |
| Caroen, SZ; Fanger, GR; Lybeck, M; Oronsky, BT; Oronsky, N; Parker, CW; Scicinski, JJ | 1 |
| Alberghina, L; Gaglio, D | 1 |
| Hintermair, J; Janzon, C; Otto, AM | 1 |
| Ding, Y; He, YC; Liu, F; Lu, Y; Rui, H; Tao, ZC; Zhang, DP; Zhang, X; Zheng, GW; Zhu, ZZ | 1 |
| Ben-Omran, T; Chaudhry, FA; Frapolli, M; Görg, B; Häberle, J; Häussinger, D; Hu, L; Ibrahim, K; Penberthy, WT; Shahbeck, N; Stucki, M | 1 |
| Bonatto, AC; Huergo, LF; Laskoski, K; Pedrosa, FO; Santos, AR; Souza, EM | 1 |
| Hoque, MM; Kanazawa, H; Kawai, G; Kondo, J; Suzuki, K; Takénaka, A; Tsunoda, M; Yamamoto, T | 1 |
| Belvin, M; Daemen, A; Hatzivassiliou, G; Kwong, M; Liang, X; O'Brien, T; Xiao, Y | 1 |
| Hong, D; Hong, KM; Kang, JH; Kim, SY; Lee, JS; Lee, SH; Son, J; Song, J | 1 |
| Chen, S; Feun, LG; Kandemir, H; Kuo, MT; Li, YY; Nguyen, DJM; Prince, JS; Savaraj, N; Shah, S; Wangpaichitr, M; Wu, C | 1 |
| Gui, DY; Luengo, A; Vander Heiden, MG | 1 |
| Ortiz de Montellano, PR | 1 |
| Blacker, T; Chew, SP; Dugourd, A; Frezza, C; Gammage, PA; Gaude, E; Minczuk, M; O'Neill, JS; Saez-Rodriguez, J; Schmidt, C; Szabadkai, G | 1 |
| Alonzo, CA; Georgakoudi, I; Karaliota, S; Karalis, KP; Liu, Z; Münger, K; Pouli, D; Quinn, KP; Varone, A | 1 |
| Diamanti, R; Gerhardt, ECM; Högbom, M; Huergo, LF; Moure, VR; Pedrosa, FO; Santos, ARS; Souza, EM | 1 |
| Halbrook, CJ; Lyssiotis, CA; Nwosu, ZC | 1 |
| Beg, MS; Hosein, AN | 1 |
| Asbury, CL; Deng, Y; Hille, B; Jung, SR; Koh, DS; Kushmerick, C | 1 |
| Chang, KT; Chuenchor, W; Doukov, TI; Gerratana, B; Resto, M; Yun, CS | 1 |
| Bernier, LP; Choi, HB; Kamyabi, A; MacVicar, BA; Weilinger, NL; York, EM | 1 |
| Cox, SE; Hart, E; Kirkham, FJ; Stotesbury, H | 1 |
| DeBerardinis, RJ; Gokhale, AS; Kota, K; Lesner, NP; Mishra, P | 1 |
| Chen, J; Chen, X; Gao, W; Hao, B; Huang, M; Huang, W; Li, K; Liu, J; Liu, Q; Liu, R; Shao, Y; Wang, J; Wang, Q; Wei, Z; Xu, P; Xu, Y; Ye, S; Zeng, S; Zhang, H; Zhang, Q; Zhong, Z | 1 |
| Banerjee, R; Carballal, S; Gupta, A; Hanna, DA; Jones, JW; Kumar, R; Libiad, M; Vitvitsky, V | 1 |
| Banerjee, U; Chi, F; Hoeve, JT; Sharpley, MS | 1 |
| Fu, X; Li, K; Li, N; Liang, H; Lin, Q; Liu, L; Luo, X; Niu, Y | 1 |
| Abiko, Y; Kobayashi, Y; Liu, S; Otani, H; Sasaki, S; Sato, S; Shinohara, Y; Takahashi, N; Wang, X; Washio, J | 1 |
| Duan, Y; Gao, X; He, X; Li, J; Li, Y; Shi, Y; Sun, H; Sun, Y; Yu, X; Zhang, C; Zhang, H; Zhang, W | 1 |
| He, P; Hou, Y; Li, N; Liu, Z; Yang, Y; Zhang, X | 1 |
| Cimpeanu, E; Dutta, D; Jafri, F; Jang, T; Lim, SH; Poplawska, M; Seong, G | 1 |
| Brand, MD; Fang, J; Gerencser, AA; Zhang, Y | 1 |
| Cai, G; Cai, L; Ge, Z; Huang, G; Sun, P; Xu, Y | 1 |
| DeBerardinis, RJ; Do, D; Faubert, B; Gu, W; Kaushik, AK; Ko, B; LaVigne, CA; Martin-Sandoval, MS; Mathews, TP; Mishra, P; Morrison, SJ; Pachnis, P; Ramesh, V; Rao, AD; Rogers, TJ; Shelton, S; Solmonson, A; Sudderth, J; Tasdogan, A; Ubellacker, JM; Wu, Z; Yang, C; Zacharias, LG; Zhao, Z | 1 |
| Bernitzky, CCM; Greetham, GM; Higuchi, Y; Horch, M; Hunt, NT; Ishii, M; Karafoulidi-Retsou, C; Kulka-Peschke, CJ; Lauterbach, L; Lenz, O; Lorent, C; Matsuura, H; Preissler, J; Procacci, B; Rippers, Y; Schulz, AC; Schulz, C; Teutloff, C; Wahlefeld, S; Wiemann, C; Wrathall, SLD; Zebger, I | 1 |
| Cao, L; Hao, B; Leng, X; Liu, G; Liu, Z; Ma, J; Niu, C; Sun, Y; Xu, C; Xu, Z; Yang, C | 1 |
| Asukai, K; Kucho, KI; Nguyen, TV | 1 |
| He, B; He, CJ; Jiang, H; Li, AM; Li, Y; Ye, J; Zhou, MN | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
15 review(s) available for nad and glutamine
| Article | Year |
|---|---|
[Mechanisms of ammonia formation in the brain].
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Oxidoreductases; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Brain Chemistry; Deamination; Dogs; Flavin-Adenine Dinucleotide; Fumarates; Glutamate Dehydrogenase; Glutaminase; Glutamine; Guanosine Triphosphate; Inosine Nucleotides; Mitochondria; Monoamine Oxidase; NAD; NADP; Nerve Tissue Proteins; Niacinamide; Oxidation-Reduction; Oxygen Consumption; Rats | 1973 |
The amidotransferases.
Topics: Anthranilate Synthase; Asparagine; Aspartic Acid; Binding Sites; Carbamates; Cytosine Nucleotides; Fructosephosphates; Glutamine; Ligases; Liver; Macromolecular Substances; NAD; Organophosphorus Compounds; Protein Conformation; Pyrimidine Nucleotides; Ribose; RNA, Transfer; Transaminases; Xanthines | 1973 |
Hormonal regulation of protein degradation in skeletal and cardiac muscle.
Topics: Adrenalectomy; Alanine; Animals; Corticosterone; Diabetes Mellitus, Experimental; Epinephrine; Fasting; Female; Glutamine; Growth Hormone; Hormones; Hydrocortisone; Insulin; Isoproterenol; Muscle Proteins; Myocardium; NAD; Pregnancy; Propranolol; Thyroxine; Triiodothyronine; Wounds and Injuries | 1981 |
Neonatal intestinal metabolism.
Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Animals; Animals, Newborn; Animals, Suckling; Citric Acid Cycle; Fatty Acids; Glucose; Glutamine; Hydroxybutyrates; Intestinal Mucosa; Ketoglutaric Acids; Lipid Metabolism; Mitochondria, Muscle; NAD; Oxidation-Reduction; Rats; Weaning | 1996 |
[Streptomyces L-glutamate oxidase: use in clinical and fundamental medicine].
Topics: Amino Acid Oxidoreductases; Ammonia; Animals; Aspartate Aminotransferases; Biosensing Techniques; Central Nervous System; Creatinine; Glutamic Acid; Glutamine; Humans; Magnesium; Mammals; NAD; NADP; Streptomyces; Urea | 1999 |
The micro-architecture of the cerebral cortex: functional neuroimaging models and metabolism.
Topics: Animals; Cerebral Cortex; Citric Acid Cycle; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycolysis; Humans; Lactates; Models, Neurological; Models, Statistical; NAD; Oxidative Phosphorylation | 2008 |
Targeting cancer metabolism: a therapeutic window opens.
Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Energy Metabolism; Enzymes; Glucose; Glutamine; Humans; Lactates; NAD; Neoplasms; Signal Transduction | 2011 |
Exploiting metabolic differences in glioma therapy.
Topics: Brain Neoplasms; Glioma; Glutamic Acid; Glutamine; Humans; Hypoxia-Inducible Factor 1; NAD; NADP; Signal Transduction | 2012 |
Targeting metabolic changes in cancer: novel therapeutic approaches.
Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; DNA-Binding Proteins; Fatty Acids; Glutamine; Humans; Isocitrate Dehydrogenase; Methotrexate; NAD; Neoplasms; Phosphopyruvate Hydratase; Signal Transduction; Tumor Suppressor Proteins | 2014 |
Follow the ATP: tumor energy production: a perspective.
Topics: Adenosine Triphosphate; Autophagy; Carrier Proteins; Energy Metabolism; Glucose; Glucose Transporter Type 1; Glutamine; Hexokinase; Humans; Kidney Neoplasms; Membrane Proteins; NAD; Neoplasms; Pentose Phosphate Pathway; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2014 |
Redox control of glutamine utilization in cancer.
Topics: Amino Acids; Antineoplastic Agents; Glutamine; Glycolysis; Humans; Lipids; Mitochondria; Mitochondrial Proteins; NAD; NADP; NADP Transhydrogenase, AB-Specific; Neoplasms; Oxidation-Reduction; Pentose Phosphate Pathway; Reactive Oxygen Species | 2014 |
Targeting Metabolism for Cancer Therapy.
Topics: Antimetabolites; Argininosuccinate Synthase; Carbohydrate Metabolism; Fatty Acids; Glutamine; Glycolysis; Humans; Isocitrate Dehydrogenase; Metabolic Engineering; NAD; Neoplasms | 2017 |
Pancreatic Cancer Metabolism: Molecular Mechanisms and Clinical Applications.
Topics: Acrylamides; Adenocarcinoma; Antineoplastic Agents; Citric Acid Cycle; Glutaminase; Glutamine; Humans; Mitochondria; Molecular Targeted Therapy; NAD; NAD(P)H Dehydrogenase (Quinone); Pancreatic Neoplasms; Piperidines | 2018 |
Metabolic Regulation: A Potential Strategy for Rescuing Stem Cell Senescence.
Topics: Cellular Senescence; Glucose; Glutamine; Lipids; NAD; Stem Cells | 2022 |
L-glutamine for sickle cell disease: more than reducing redox.
Topics: Anemia, Sickle Cell; Glutamine; Hemoglobinopathies; Humans; NAD; Oxidation-Reduction; Volatile Organic Compounds | 2022 |
1 trial(s) available for nad and glutamine
| Article | Year |
|---|---|
Oral L-glutamine therapy for sickle cell anemia: I. Subjective clinical improvement and favorable change in red cell NAD redox potential.
Topics: Administration, Oral; Adult; Anemia, Sickle Cell; Dietary Supplements; Erythrocytes; Glutamine; Humans; Middle Aged; NAD; Oxidation-Reduction; Pilot Projects; Treatment Outcome | 1998 |
150 other study(ies) available for nad and glutamine
| Article | Year |
|---|---|
Energy-dependent incorporation of sphingolipid precursors and fatty acids in Bacteriodes melaninogenicus.
Topics: Acetates; Asparagine; Bacteroides; Ceramides; Energy Metabolism; Glutamine; Kinetics; NAD; Palmitates; Prevotella melaninogenica; Sphingosine; Vitamin K | 1977 |
Role of nucleosides, 5-phosphoribosyl-1-pyrophosphate, and ribose 1-phosphate in the biosynthesis of phosphosphingolipids in Bacteroides melaninogenicus.
Topics: Bacteroides; Ceramides; Glutamine; NAD; Nucleosides; Pentosephosphates; Phospholipids; Phosphoribosyl Pyrophosphate; Prevotella melaninogenica; Ribosemonophosphates; Spheroplasts; Sphingolipids | 1978 |
Glutamine and asparagine as nitrogen donors for reductant-dependent glutamate synthesis in pea roots.
Topics: Ammonia; Asparagine; Glutamates; Glutamine; Kinetics; NAD; Oxidation-Reduction; Plants | 1975 |
On the utilization of L-glutamine by glutamate dehydrogenase.
Topics: Adenosine Triphosphate; Animals; Cattle; Glutamate Dehydrogenase; Glutamine; Kinetics; Liver; Magnesium; NAD | 1976 |
Effect of an ammonia load on the kidney near-equilibrium systems in the rat in vivo.
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Fasting; Female; Gluconeogenesis; Glutamine; Ketoglutaric Acids; Kidney; Kidney Tubules; Kinetics; NAD; Oxidation-Reduction; Rats | 1976 |
[Polypeptide synthetase activity of chromatin from eukaryotic cells].
Topics: Aminoacylation; Animals; Asparagine; Chromatin; Glutamates; Glutamine; Glycine; Hepatectomy; Liver; Male; NAD; Niacinamide; Peptide Biosynthesis; Poly Adenosine Diphosphate Ribose; Rats; Thymidine | 1978 |
Glutamate synthase in blue-green algae.
Topics: Ammonia; Cyanobacteria; Dithionite; Ferredoxins; Glutamate Synthase; Glutamates; Glutamine; Ketoglutaric Acids; NAD; NADP; Nitrogen; Transaminases | 1975 |
On mechanisms in hyperammonemic coma--with particular reference to hepatic encephalopathy.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ammonia; Aspartic Acid; Brain; Dose-Response Relationship, Drug; Energy Metabolism; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hepatic Encephalopathy; Humans; Ketoglutaric Acids; Mitochondria, Liver; NAD; Oxidation-Reduction; Time Factors | 1975 |
Pathways and regulation of glutamate synthesis in a Corynebacterium sp. overproducing glutamate.
Topics: Ammonium Sulfate; Cell-Free System; Corynebacterium; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Ketoglutaric Acids; Lysine; NAD; NADP; Nitrates; Soil Microbiology | 1975 |
Characterization of two site-specifically mutated human dihydrolipoamide dehydrogenases (His-452----Gln and Glu-457----Gln).
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Dihydrolipoamide Dehydrogenase; Escherichia coli; Flavin-Adenine Dinucleotide; Genetic Vectors; Glutamates; Glutamic Acid; Glutamine; Histidine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligodeoxyribonucleotides; Protein Conformation; Recombinant Proteins | 1992 |
Anisoosmostic liver perfusion: redox shifts and modulation of alpha-ketoisocaproate and glycine metabolism.
Topics: Animals; Cell Size; Glucagon; Glutamine; Glycine; Keto Acids; Ketones; Liver; Male; Mitochondria, Liver; NAD; Osmolar Concentration; Osmosis; Oxidation-Reduction; Perfusion; Rats; Rats, Wistar | 1992 |
Effects of congenital hyperammonemia on the cerebral and hepatic levels of the intermediates of energy metabolism in spf mice.
Topics: Adenosine Triphosphate; Ammonia; Animals; Brain; Coenzyme A; Energy Metabolism; Glucose; Glutamine; Ketoglutaric Acids; Liver; Mice; Mice, Mutant Strains; NAD; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Oxidation-Reduction; Pyruvates; Pyruvic Acid; X Chromosome | 1992 |
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
Topics: Adenosine Diphosphate Ribose; Affinity Labels; Aspartic Acid; Base Sequence; Binding Sites; Diphtheria Toxin; Glutamates; Glutamic Acid; Glutamine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Serine; Substrate Specificity | 1990 |
General base catalysis in a glutamine for histidine mutant at position 51 of human liver alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Binding, Competitive; Catalysis; Decanoic Acids; Ethanol; Glutamine; Histidine; Humans; Isoenzymes; Kinetics; Liver; Mutagenesis; NAD; Trifluoroethanol | 1991 |
NAD synthesis by erythrocytes in phosphoribosylpyrophosphate synthetase (PRPPs) superactivity.
Topics: Child; Erythrocytes; Female; Glutamine; Humans; Male; NAD; Niacin; Niacinamide; Phosphotransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Ribose-Phosphate Pyrophosphokinase | 1989 |
Oxidation of cytosolic NADH by the malate-aspartate shuttle in MC29 hepatoma cells.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Chickens; Cytosol; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1989 |
Crabtree effect in tumoral pancreatic islet cells.
Topics: Adenine Nucleotides; Adenoma, Islet Cell; Animals; Glucose; Glutamine; Lactates; Lactic Acid; Lipids; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Pancreatic Neoplasms; Tumor Cells, Cultured | 1988 |
Defective catabolism of D-glucose and L-glutamine in mouse pancreatic islets maintained in culture after streptozotocin exposure.
Topics: Animals; Aspartate Aminotransferases; Cells, Cultured; Cytosol; Diabetes Mellitus, Experimental; Glucokinase; Glucose; Glutamate Dehydrogenase; Glutamine; Glyceraldehyde-3-Phosphate Dehydrogenases; Hexokinase; Islets of Langerhans; Male; Mice; Mitochondria; NAD; NADP; Streptozocin | 1988 |
Substrate utilization for lactate and energy production by heat-shocked L929 cells.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Cell Line; Citric Acid Cycle; Energy Metabolism; Fibroblasts; Glucose; Glutamine; Heat-Shock Proteins; Lactates; Lactic Acid; Mice; NAD; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Pyruvic Acid; Temperature | 1986 |
Malate-citrate cycle during glycolysis and glutaminolysis in Ehrlich ascites tumor cells.
Topics: Animals; Benzene Derivatives; Carcinoma, Ehrlich Tumor; Citrates; Citric Acid; Cytosol; Female; Glucose; Glutamine; Glycolysis; Malate Dehydrogenase; Malates; Mice; Mitochondria; NAD; Oxygen Consumption; Tricarboxylic Acids | 1987 |
Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion.
Topics: Animals; Carboxylic Acids; Cytosol; Fructose; Glucose; Glutamine; Insulin; Islets of Langerhans; Leucine; Male; Mice; NAD; NADP | 1987 |
A single amino acid substitution deregulates a bacterial lactate dehydrogenase and stabilizes its tetrameric structure.
Topics: Allosteric Regulation; Allosteric Site; Arginine; Bacterial Proteins; Binding Sites; Fructosediphosphates; Geobacillus stearothermophilus; Glutamine; L-Lactate Dehydrogenase; Mutation; NAD; Protein Binding; Protein Conformation; Pyruvates; Pyruvic Acid | 1987 |
Intracellular distribution of some enzymes of the glutamine utilisation pathway in rat lymphocytes.
Topics: Animals; Aspartate Aminotransferases; Cell Compartmentation; Cytosol; Glutamine; Lymphocytes; Malate Dehydrogenase; Malates; Mitochondria; NAD; Oxaloacetates; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvate Carboxylase; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats | 1986 |
Presence of glutamate synthase in fission yeasts and its possible role in ammonia assimilation.
Topics: Ammonia; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Ketoglutaric Acids; NAD; NADP; Saccharomyces; Transaminases | 1973 |
Studies on possible routes of ammonium assimilation in soybean root nodule bacteroids.
Topics: Alanine; Amino Acid Oxidoreductases; Ammonium Chloride; Azaserine; Carbon Radioisotopes; Cell-Free System; Chloromercuribenzoates; Chromatography, Thin Layer; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Glycine max; Hydrogen-Ion Concentration; Ketoglutaric Acids; NAD; Nitrogen; Plants; Pyruvates; Rhizobium; Spectrophotometry | 1973 |
Evidence for the presence of glutamate synthase in extracts of carrot cell cultures.
Topics: Ammonium Chloride; Asparagine; Cells, Cultured; Chromatography, Gel; Dialysis; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Kinetics; NAD; NADP; Nitrates; Oxidation-Reduction; Plants; Spectrophotometry, Ultraviolet; Transaminases | 1974 |
Glutamate synthetase type activity in higher plants.
Topics: Asparagine; Cells, Cultured; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Isoenzymes; Ketoglutaric Acids; Kinetics; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Plants; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors; Transaminases | 1974 |
Absence of involvement of glutamine synthetase and of NAD-linked glutamate dehydrogenase in the nitrogen catabolite repression of arginase and other enzymes in Saccharomyces cerevisiae.
Topics: Allantoin; Alleles; Amidohydrolases; Ammonia; Arginase; Enzyme Repression; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Mutation; NAD; NADP; Nitrogen; Saccharomyces cerevisiae; Species Specificity | 1974 |
Effects of D-glutamate on mycelial growth and glutamate dehydrogenase enzymes of Coprinus lagopus.
Topics: Acetates; Basidiomycota; Cell-Free System; Glucose; Glutamate Dehydrogenase; Glutamates; Glutamine; Isoenzymes; Ketoglutaric Acids; Kinetics; NAD; NADP; Quaternary Ammonium Compounds; Spectrophotometry; Stereoisomerism; Urea | 1974 |
Feedback inhibition of glutamine synthetase of Neurospora crassa by nicotinamide-adenine dinucleotide.
Topics: Adenosine Triphosphate; Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Feedback; Glutamates; Glutamine; Guanine Nucleotides; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Ligases; NAD; Neurospora; ortho-Aminobenzoates; Phenylalanine; Quaternary Ammonium Compounds; Tryptophan; Tyrosine | 1968 |
The significance of intermediary plateau regions in enzyme saturation curves.
Topics: Binding Sites; Carboxy-Lyases; Chemical Phenomena; Chemistry; Coenzyme A; Cytosine Nucleotides; Enzymes; Glutamate Dehydrogenase; Glutamine; Kinetics; Ligases; Mathematics; NAD; Pyruvates | 1969 |
Glutamine synthetase of Neurospora crassa. Inactivation by urea and protection by some substrates and allosteric effectors.
Topics: Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Glutamates; Glutamine; Glycine; Histidine; Ligases; Magnesium; Molecular Weight; NAD; Neurospora; ortho-Aminobenzoates; Sulfhydryl Compounds; Urea | 1969 |
NAD biosynthesis in rabbit erythrocytes and reticulocytes after whole-body x-irradiation.
Topics: Animals; Erythrocytes; Glucose; Glutamine; Hexokinase; Magnesium; Methylene Blue; NAD; Niacinamide; Nicotinic Acids; Nucleosides; Oxidation-Reduction; Rabbits; Radiation Effects; Reticulocytes | 1969 |
Effects of ischaemia on metabolite concentrations in rat liver.
Topics: Acetoacetates; Adenine Nucleotides; Alanine; Ammonia; Animals; Aspartic Acid; Cycloserine; Freezing; Glutamate Dehydrogenase; Glutamates; Glutamine; Glutarates; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Ischemia; Kinetics; Lactates; Liver; Liver Circulation; Malates; Male; Mitochondria, Liver; NAD; Pyruvates; Rats | 1970 |
A continuous spectrophotometric method for ammonia-generating reactions.
Topics: Adenosine Triphosphate; Amidohydrolases; Ammonia; Glutamine; L-Lactate Dehydrogenase; Ligases; Methods; NAD; Pyruvate Kinase; Spectrophotometry; Urease | 1970 |
Effects of ischaemia on content of metabolites in rat liver and kidney in vivo.
Topics: Acetoacetates; Adenine Nucleotides; Adenosine Triphosphate; Ammonia; Animals; Glucosyltransferases; Glutamates; Glutamine; Glutarates; Glycerophosphates; Glycolysis; Hexosephosphates; Hydroxybutyrates; Ischemia; Kidney; Lactates; Liver; NAD; Phosphates; Phosphofructokinase-1; Pyruvate Kinase; Rats; Starvation; Trioses | 1970 |
A spectrophotometric method for the simultaneous measurement of L-glutamine and L-asparagine in biological materials.
Topics: Aminohydrolases; Ammonia; Animals; Arginine; Asparagine; Brain; Escherichia coli; Evaluation Studies as Topic; Glutamate Dehydrogenase; Glutamine; Hot Temperature; Humans; Ketoglutaric Acids; Liver; Methionine Sulfoximine; Methods; Mice; NAD; Peptide Hydrolases; Spectrophotometry; Time Factors; Trichloroacetic Acid | 1971 |
Enzymic assays for amoonia and L-glutamine in tissue extracts.
Topics: Ammonia; Animals; Buffers; Glutamate Dehydrogenase; Glutaminase; Glutamine; Glycerol; Ketoglutaric Acids; Liver; Liver Extracts; Male; Methods; NAD; Oxidation-Reduction; Phosphates; Rats; Spectrophotometry | 1971 |
Fluorometric measurement of glutamine and asparagine using enzymic methods.
Topics: Adenine Nucleotides; Animals; Asparaginase; Asparagine; Aspartate Aminotransferases; Cerebral Cortex; Escherichia coli; Fluorometry; Glutamate Dehydrogenase; Glutaminase; Glutamine; Hydrolysis; Ketoglutaric Acids; Malate Dehydrogenase; Methods; NAD; Rats | 1971 |
Rate-limiting factor in rat kidney slice ammoniagenesis.
Topics: Ammonia; Animals; Arsenicals; Dinitrophenols; Gluconeogenesis; Glutamate Dehydrogenase; Glutamates; Glutamine; In Vitro Techniques; Ketoglutaric Acids; Kidney; Male; Methylene Blue; NAD; Oxygen Consumption; Rats | 1971 |
The effect of ketone bodies on renal ammoniogenesis.
Topics: Acetoacetates; Acidosis; Ammonia; Ammonium Chloride; Animals; Bicarbonates; Citric Acid Cycle; Coenzyme A; Depression, Chemical; Dogs; Female; Glutamates; Glutamine; Hydrogen-Ion Concentration; Hydroxybutyrates; Ketoglutaric Acids; Ketone Bodies; Kidney; Kidney Tubules; Lactates; Mannitol; Mitochondria; NAD; Oxaloacetates; Urine | 1971 |
Mechanisms of active transport in isolated membrane vesicles. 2. The coupling of reduced phenazine methosulfate to the concentrative uptake of beta-galactosides and amino acids.
Topics: Amino Acids; Amobarbital; Ascorbic Acid; Bacillus megaterium; Bacillus subtilis; Biological Transport, Active; Cell Membrane; Chloromercuribenzoates; Cyanides; Cyclic N-Oxides; Electron Transport; Escherichia coli; Glutamine; Lactose; Lysine; NAD; Oxygen; Phenazines; Proline; Proteus; Pseudomonas; Quinolines; Salmonella typhimurium; Stimulation, Chemical; Sulfuric Acids | 1971 |
Ethanol and the metabolic interrelations of carbohydrates and amino acids in brain preparations.
Topics: Adenosine Triphosphate; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbohydrate Metabolism; Carbon Isotopes; Ethanol; Glucose; Glucosephosphates; Glutamine; Hexokinase; In Vitro Techniques; Lactates; NAD; Pyruvates; Rats; Rats, Inbred Strains | 1972 |
Purification and properties of yeast nicotinamide adenine dinucleotide synthetase.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Chromatography, Ion Exchange; Chromatography, Paper; Cobalt; Drug Stability; Electrophoresis, Disc; Glutamine; Isoflurophate; Kinetics; Ligases; Magnesium; Manganese; Molecular Weight; NAD; Phosphorus Isotopes; Time Factors; Yeasts | 1972 |
Transients and cooperativity. A slow transition model for relating transients and cooperative kinetics of enzymes.
Topics: Adenosine Monophosphate; Alcohol Oxidoreductases; Allosteric Regulation; Aminohydrolases; Binding Sites; Carboxy-Lyases; Enzymes; Glutamine; Hexokinase; Hexosaminidases; Homoserine; Kinetics; L-Lactate Dehydrogenase; Mathematics; Models, Chemical; NAD; Oxaloacetates; Oxidoreductases; Pentosephosphates; Pentosyltransferases; Phosphoenolpyruvate; Protein Binding; Protein Conformation; Pyruvate Kinase; Thermodynamics; Threonine | 1972 |
Glutamate synthase: properties of the reduced nicotinamide adenine dinucleotide-dependent enzyme from Saccharomyces cerevisiae.
Topics: Amino Acid Oxidoreductases; Ammonium Sulfate; Cell-Free System; Chemical Precipitation; Chlorides; Chromatography, DEAE-Cellulose; Chromatography, Gel; Culture Media; Glutamate Dehydrogenase; Glutamates; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Ketoglutaric Acids; Manganese; NAD; Saccharomyces cerevisiae; Spectrophotometry | 1974 |
Glutamate and aspartate transport in rat brain mitochondria.
Topics: Animals; Aspartic Acid; Biological Transport; Brain; Glutamates; Glutaminase; Glutamine; In Vitro Techniques; Kidney; Malates; Mitochondria; Mitochondria, Liver; NAD; Osmosis; Potassium; Quaternary Ammonium Compounds; Rats; Swine; Valinomycin | 1974 |
Regulation of glutamate dehydrogenases during morphogenesis of Schizophyllum commune.
Topics: Ammonia; Basidiomycota; Cell Differentiation; Glutamate Dehydrogenase; Glutamine; Guanine Nucleotides; NAD; NADP; Spores | 1967 |
Nitrogen metabolism in the perfused rat liver.
Topics: Alanine; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Glutamate Dehydrogenase; Glutamates; Glutamine; Hydroxybutyrate Dehydrogenase; Liver; NAD; NADP; Nitrogen; Perfusion; Rats; Stimulation, Chemical; Urea | 1970 |
Glutamine synthetase from Nocardia corallina.
Topics: Amino Acids; Carbamates; Feedback; Glucosamine; Glutamine; Ligases; NAD; NADP; Nocardia; Nucleotides | 1971 |
Conversion of the alpha-hydroxy and alpha-keto analogues of methionine to methionine by cell-free extracts of adult female Ascaris suum.
Topics: Ascaris; Asparagine; Aspartic Acid; Butyrates; Cell-Free System; Female; Glutamates; Glutamine; Methionine; NAD; NADP; Oxidation-Reduction; Proteins | 1971 |
Inactivation in vivo of glutamine synthetase and NAD-specific glutamate dehydrogenase: its role in the regulation of glutamine synthesis in yeasts.
Topics: Ammonia; Candida; Culture Media; Enzyme Repression; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Mitosporic Fungi; NAD; Saccharomyces; Saccharomyces cerevisiae | 1971 |
[Glutamate cycle, first step of nitrogen metabolism in Bacillus megaterium].
Topics: Alanine; Allosteric Regulation; Amino Acid Oxidoreductases; Ammonia; Aspartic Acid; Bacillus megaterium; Enzyme Repression; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Ketoglutaric Acids; Lyases; Mutation; NAD; NADP; Nitrogen; Oxaloacetates; Oxidoreductases; Pyruvates; Transaminases | 1972 |
Incorporation of ammonium in amino acids by Trypanosoma cruzi.
Topics: Ammonia; Animals; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Trypanosoma cruzi | 1980 |
Ammonia formation from some amino acids by human term placental mitochondria.
Topics: Adenosine Diphosphate; Amino Acids; Ammonia; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Mitochondria; Models, Biological; NAD; Placenta; Pregnancy | 1982 |
The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme.
Topics: Animals; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glutamic Acid; Glutamine; Kidney; Kinetics; Leukemia L1210; Liver Neoplasms, Experimental; Malate Dehydrogenase; Male; Mice; Mice, Inbred Strains; Mitochondria; Mitochondria, Liver; NAD; NADP; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thymoma; Thymus Neoplasms | 1984 |
Regulation of glutamine-repressible gene products by the GLN3 function in Saccharomyces cerevisiae.
Topics: Ammonia; Chromosome Mapping; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Molecular Weight; Mutation; NAD; Phenotype; Saccharomyces cerevisiae | 1984 |
NADH-dependent glutamate synthase and nitrogen metabolism in Neurospora crassa.
Topics: Glutamate Synthase; Glutamates; Glutamine; Kinetics; Mutation; NAD; Neurospora; Neurospora crassa; Nitrogen; Species Specificity; Transaminases | 1980 |
Regulation and function of glutamate synthase in Neurospora crassa.
Topics: Ammonia; Glutamate Synthase; Glutamates; Glutamine; Kinetics; Mutation; NAD; NADP; Neurospora; Neurospora crassa; Species Specificity; Transaminases | 1980 |
Prevention of ammonia toxicity by L-carnitine: metabolic changes in brain.
Topics: Acetates; Animals; Brain; Carnitine; Glutamine; Kinetics; Male; Mice; Microsomes; Mitochondria; NAD; Oxidation-Reduction | 1984 |
The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic interaction of L-glutamine and 2-ketoisocaproate in pancreatic islets.
Topics: Animals; Drug Synergism; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Transaminases | 1981 |
The reconstitution of binding protein-dependent active transport of glutamine in isolated membrane vesicles from Escherichia coli.
Topics: Biological Transport, Active; Carrier Proteins; Cell Membrane; Escherichia coli; Glutamine; Kinetics; NAD | 1981 |
The stimulus-secretion coupling of amino acid-induced insulin release. Influence of a nonmetabolized analog of leucine on the metabolism of glutamine in pancreatic islets.
Topics: Adenine Nucleotides; Amino Acids; Amino Acids, Cyclic; Animals; Glutamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; NAD; NADP; Oxidation-Reduction; Rats | 1982 |
Noncarbohydrate nutrients protect against alloxan-induced inhibition of insulin release.
Topics: Alloxan; Amino Acids; Animals; Glucose; Glutamine; Insulin; Islets of Langerhans; Keto Acids; Leucine; NAD; NADP; Rats; Time Factors | 1982 |
The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine.
Topics: Animals; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Models, Biological; NAD; NADP; Rats | 1982 |
Ketone body effects on glutamine metabolism in isolated kidneys and mitochondria.
Topics: 3-Hydroxybutyric Acid; Ammonia; Animals; Glomerular Filtration Rate; Glutamate Dehydrogenase; Glutamine; Hydroxybutyrates; Ketone Bodies; Kidney; Male; Mitochondria; NAD; Rats; Rats, Inbred Strains; Urination | 1982 |
Free amino acids in the brain of ethanol treated rats.
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport; Brain Chemistry; Ethanol; gamma-Aminobutyric Acid; Glutamates; Glutamine; Male; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1982 |
pH and hormonal regulation of ammoniagenesis in cultured OK cells.
Topics: Ammonia; Animals; Cell Line; Glutamine; Hormones; Hydrogen-Ion Concentration; Kidney; NAD; Opossums; Serine | 1994 |
Changes in the NAD(P)H concentration caused by addition of nitrogenase 'switch-off' effectors in Rhodospirillum rubrum G-9, as measured by fluorescence.
Topics: Ammonia; Darkness; Glutamine; Light; NAD; NADP; Nitrogen Fixation; Nitrogenase; Oxidation-Reduction; Oxygen; Rhodospirillum rubrum; Spectrometry, Fluorescence | 1994 |
Glycerol 3-phosphate and lactate as indicators of the cerebral cytoplasmic redox state in severe and mild hypoxia respectively: a 13C- and 31P-n.m.r. study.
Topics: Acetates; Adenosine Triphosphate; Alanine; Cerebral Cortex; Cytoplasm; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycerophosphates; Hypoxia, Brain; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Oxidation-Reduction; Phosphocreatine | 1993 |
The role of reduced nicotinamide adenine dinucleotide phosphate in glucose- and temperature-dependent doxorubicin cytotoxicity.
Topics: Animals; Cell Survival; Culture Media; DNA Damage; Doxorubicin; Drug Resistance; Glucose; Glutamine; L Cells; Methylene Blue; Mice; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Temperature; Uridine | 1993 |
Molecular characterization of an NAD-specific glutamate dehydrogenase gene inducible by L-glutamine. Antisense gene pair arrangement with L-glutamine-inducible heat shock 70-like protein gene.
Topics: Amino Acid Sequence; Base Sequence; Codon; DNA Primers; Enzyme Induction; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Overlapping; Glutamate Dehydrogenase; Glutamine; Heat-Shock Proteins; Introns; Molecular Sequence Data; NAD; Neurospora crassa; Oomycetes; Restriction Mapping; RNA, Fungal; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid | 1994 |
Pertussis toxin treatment increases glutamate release and dihydropyridine binding sites in cultured rat cerebellar granule neurons.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Baclofen; Barium; Binding Sites; Calcium; Calcium Channels; Cells, Cultured; Cerebellum; Cyclic AMP; Dihydropyridines; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamine; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Membrane Potentials; NAD; Neurons; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella | 1993 |
Effects of ethanol on urinary acidification and on gluconeogenesis by isolated renal tubules.
Topics: Amino Acids; Animals; Carbohydrate Metabolism; Cytosol; Diet; Ethanol; Female; Fomepizole; Gluconeogenesis; Glucose; Glutamine; Hydrogen-Ion Concentration; Kidney Tubules; Lactates; Lactic Acid; Male; Mitochondria; NAD; Oleic Acid; Oleic Acids; Oxidation-Reduction; Pyrazoles; Pyruvates; Rats; Rats, Wistar; Serum Albumin; Time Factors; Urine | 1993 |
[Effect of glucose and glutamine on the intensity of NAD precursor use in rats with transplanted tumors].
Topics: Animals; Carcinoma 256, Walker; Glucose; Glutamine; Kidney; Liver; Lymphoma, Non-Hodgkin; NAD; Neoplasm Transplantation; Niacin; Niacinamide; Rats | 1995 |
Oxygen activation by cytochrome P450BM-3: effects of mutating an active site acidic residue.
Topics: Bacterial Proteins; Binding Sites; Cytochrome P-450 Enzyme System; Enzyme Activation; Glutamic Acid; Glutamine; Hydroxylation; Laurates; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Myristates; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxygen Consumption; Palmitates; Protein Structure, Secondary; Substrate Specificity | 1997 |
The anaerobic fungus Piromyces sp. strain E2: nitrogen requirement and enzymes involved in primary nitrogen metabolism.
Topics: Albumins; Allantoin; Amino Acids; Ammonia; Anaerobiosis; Fungi; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamine; NAD; Nitrites; Nitrogen; Quaternary Ammonium Compounds; Transaminases; Urea | 1996 |
The potential roles of the conserved amino acids in human liver mitochondrial aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amino Acid Sequence; Amino Acids; Animals; Cattle; Conserved Sequence; Glutamine; Humans; Kinetics; Lysine; Mitochondria, Liver; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Sequence Alignment | 1997 |
Increased red cell glutamine availability in sickle cell anemia: demonstration of increased active transport, affinity, and increased glutamate level in intact red cells.
Topics: Anemia, Sickle Cell; Biological Transport, Active; Erythrocytes; Glutamic Acid; Glutamine; Humans; Kinetics; NAD | 1997 |
Stimulation of oxygen consumption promotes mitochondrial calcium accumulation, a process associated with, and causally linked to, enhanced formation of tert-butylhydroperoxide-induced DNA single-strand breaks.
Topics: 3-Hydroxybutyric Acid; Caffeine; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Catalase; DNA Damage; DNA, Single-Stranded; Electron Transport; Glucose; Glutamine; Humans; Hydrogen Peroxide; Hydroxybutyrates; Kinetics; Leukemia, Myeloid; Mitochondria; NAD; Oxygen Consumption; Peroxides; Pyruvates; Reactive Oxygen Species; Rotenone; tert-Butylhydroperoxide; Tumor Cells, Cultured | 1997 |
Simple and rapid method for determining nicotinamide adenine dinucleotide synthetase activity by high-performance liquid chromatography.
Topics: Adenosine Triphosphate; Amide Synthases; Chromatography, High Pressure Liquid; Glutamine; Humans; Lead; Male; NAD; Occupational Exposure | 1997 |
Control of coenzyme binding to horse liver alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Animals; Arginine; Coenzymes; Computer Simulation; Glutamine; Histidine; Horses; Hydrogen-Ion Concentration; Kinetics; Liver; Lysine; Mutagenesis, Site-Directed; NAD; Protein Binding | 1999 |
Determination of NADH-dependent glutamate synthase (GOGAT) in Spodoptera frugiperda (Sf9) insect cells by a selective 1H/15N NMR in vitro assay.
Topics: Animals; Cell Line; Cell-Free System; Glutamate Synthase; Glutaminase; Glutamine; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; NAD; Nitrogen Isotopes; Quaternary Ammonium Compounds; Spectrophotometry; Spodoptera | 2000 |
Energetic requirement of carbachol-induced Ca2+ signaling in single mouse beta-cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Culture Media; Energy Metabolism; Female; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Mice; NAD; Pyruvates; Signal Transduction; Type C Phospholipases | 2000 |
Delineation of the roles of amino acids involved in the catalytic functions of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase.
Topics: Arginine; Binding Sites; Catalysis; Conserved Sequence; Dimerization; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Glutamine; Kinetics; Leuconostoc; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Proline; Thermodynamics | 2000 |
Rates of gluconeogenesis in perfused liver of alloxan-diabetic fed rats.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Fructose; Gluconeogenesis; Glucose; Glutamine; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Uric Acid | 2000 |
Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Enzyme Activation; Escherichia coli; Folic Acid; Glutamic Acid; Glutamine; Kinetics; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Spectrophotometry; Vitamin K | 2001 |
Effect of exogenous lactate on rat glioma metabolism.
Topics: Animals; Blood Glucose; Brain; Brain Neoplasms; Carbon; Carbon Radioisotopes; Citric Acid Cycle; Energy Metabolism; Female; Glioma; Glucose; Glutamine; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Neurons; Rats; Rats, Wistar; Tumor Cells, Cultured | 2001 |
Identification of tissue transglutaminase-reactive lysine residues in glyceraldehyde-3-phosphate dehydrogenase.
Topics: Animals; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Glutamine; Glyceraldehyde-3-Phosphate Dehydrogenases; Lysine; Mass Spectrometry; Microscopy, Fluorescence; Models, Molecular; NAD; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Swine; Time Factors; Transglutaminases | 2002 |
Human aldehyde dehydrogenase catalytic activity and structural interactions with coenzyme analogs.
Topics: Adult; Aldehyde Dehydrogenase; Algorithms; Catalysis; Catalytic Domain; Computer Simulation; Glutamine; Humans; Isoenzymes; Kinetics; Liver; NAD; Quantum Theory; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2001 |
Comparison of the effects of ammonia on brain mitochondrial function in rats and gulf toadfish.
Topics: Ammonia; Animals; Antimycin A; Batrachoidiformes; Brain; Cyanides; Electron Transport; Glutamine; Hepatic Encephalopathy; Hyperammonemia; Mitochondria; NAD; Organ Culture Techniques; Rats; Rats, Wistar; Rotenone; Species Specificity; Uncoupling Agents | 2002 |
Glutamine 132 in the NAD(H)-binding component of proton-translocating transhydrogenase tethers the nucleotides before hydride transfer.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Binding Sites; Crystallization; Crystallography, X-Ray; Electron Transport; Glutamine; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; NADP Transhydrogenases; Protons; Recombinant Proteins; Rhodospirillum rubrum | 2003 |
The reported human NADsyn2 is ammonia-dependent NAD synthetase from a pseudomonad.
Topics: Amide Synthases; Ammonia; Base Sequence; Chromosomes, Human, Pair 22; Cloning, Molecular; CpG Islands; Cysteine; DNA; Gene Library; Glutamic Acid; Glutamine; Humans; Hydrolysis; Molecular Sequence Data; Muscles; NAD; Nicotinamidase; Open Reading Frames; Operon; Phylogeny; Protein Structure, Tertiary; Pseudomonas; Sequence Homology, Nucleic Acid | 2003 |
[Enrichment and separation of a diphosphopyridine nucleotide specific and a triphosphopyridine nucleotide specific glutamine acid dehydrogenase from yeast].
Topics: Glutamine; NAD; NADP; Oxidoreductases; Rare Diseases; Retinal Degeneration; Retinal Detachment; Saccharomyces cerevisiae; Yeast, Dried | 1957 |
STUDIES ON MORPHINE. IV. EFFECTS OF SOME METABOLITES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
Topics: Alanine; Cyanides; Fluoroacetates; Glutamine; Iodoacetates; Mice; Morphine; NAD; Nalorphine; Niacin; Niacinamide; Pharmacology; Pyridines; Pyridoxine; Research; Serine; Toxicology; Tryptophan | 1963 |
WATER CONTENT OF PAPER AS A VARIABLE IN PAPER CHROMATOGRAPHY.
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Aspartic Acid; Autoradiography; Carbon Isotopes; Chromatography; Chromatography, Paper; Escherichia coli; Formates; Fumarates; Glutamates; Glutamine; Guanine Nucleotides; Humidity; Hypoxanthines; Lactates; Malates; NAD; Nucleosides; Nucleotides; Research; Water; Xanthines | 1964 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
NICOTINAMIDE ADENINE DINUCLEOTIDE SYNTHESIS IN ASCITES CELLS IN VITRO.
Topics: Ascites; Carbon Isotopes; Chromatography; Glucose; Glutamine; In Vitro Techniques; Metabolism; Mice; NAD; Niacin; Niacinamide; Nicotinic Acids; Phosphates; Phosphorus Isotopes; Research; Tissue Culture Techniques | 1964 |
STUDIES ON SPECIFIC ENZYME INHIBITORS. 8. ENZYME-REGULATORY MECHANISM OF THE ENTRY OF GLUTAMIC ACID INTO METABOLIC PATHWAYS IN KIDNEY TISSUE.
Topics: Acetates; Adenosine Triphosphate; Alanine Transaminase; Aspartate Aminotransferases; Enzyme Inhibitors; Glutamates; Glutamic Acid; Glutamine; Glutarates; Hexokinase; Kidney; Malates; Metabolic Networks and Pathways; Metabolism; Mitochondria; NAD; Oxalates; Pyruvates; Rats; Research | 1964 |
(14-C)FORMATE UTILIZATION IN CELL-FREE EXTRACTS OF EHRLICH ASCITES CELLS.
Topics: Ammonium Chloride; Animals; Ascites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Citrates; Enzyme Inhibitors; Formates; Glucose; Glutamine; Metabolism; NAD; Pharmacology; Research; Ribose; Spectrophotometry | 1964 |
Substrate specificity of glutaminyl cyclases from plants and animals.
Topics: Amino Acids; Aminoacyltransferases; Animals; Carica; Catalysis; Cattle; Cyclization; Dipeptides; Enzyme Stability; Gastrins; Glutamate Dehydrogenase; Glutamine; Gonadotropin-Releasing Hormone; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; NAD; Neurotensin; Oligopeptides; Osmolar Concentration; Pyrrolidonecarboxylic Acid; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Thyrotropin-Releasing Hormone | 2003 |
Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Catalytic Domain; Crystallography, X-Ray; Deuterium Exchange Measurement; Glutamine; Histidine; Horses; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Liver; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; NAD | 2004 |
NAD deamidation "a new reaction" by an enzyme from Aspergillus terreus DSM 826.
Topics: Acetamides; Acrylic Resins; Asparagine; Aspergillus; Chromatography, Liquid; Deamination; Enzyme Inhibitors; Enzyme Stability; Freezing; Glutamine; Hydrogen-Ion Concentration; Kinetics; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Substrate Specificity; Temperature | 2005 |
The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae.
Topics: Binding Sites; Carbohydrate Epimerases; Cloning, Molecular; Crystallography, X-Ray; Cytoplasm; Electrons; Escherichia coli; Glutamine; Humans; Models, Chemical; Models, Molecular; NAD; Oxygen; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Racemases and Epimerases; Saccharomyces cerevisiae; Serine; UDPglucose 4-Epimerase | 2005 |
Identification of key amino acids responsible for the substantially higher affinities of human type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD1) for substrates, coenzymes, and inhibitors relative to human 3beta-HSD2.
Topics: 3-Hydroxysteroid Dehydrogenases; Allosteric Site; Amino Acid Sequence; Androstenols; Animals; Arginine; Baculoviridae; Blotting, Western; Catalysis; Catalytic Domain; Cell Line; Dihydrotestosterone; DNA Primers; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamine; Histidine; Humans; Insecta; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NAD; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Tissue Distribution | 2005 |
Increase in NADH-glutamate dehydrogenase activity by mercury in excised bean leaf segments.
Topics: Aluminum; Dose-Response Relationship, Drug; Fabaceae; Glutamate Dehydrogenase; Glutamine; Glutathione; Kinetics; Mercury; NAD; Phaseolus; Plant Leaves; Sucrose; Sulfhydryl Compounds | 2005 |
Comparative genomics of NAD biosynthesis in cyanobacteria.
Topics: Amide Synthases; Cyanobacteria; Escherichia coli; Gene Transfer, Horizontal; Genome, Bacterial; Glutamine; Models, Biological; Multigene Family; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nucleotidyltransferases; Pentosyltransferases; Synteny | 2006 |
Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2.
Topics: Amino Acid Sequence; Catalysis; Crystallography, X-Ray; Dinoprostone; Escherichia coli; Glutamine; Humans; Hydroxyprostaglandin Dehydrogenases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction | 2006 |
Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.
Topics: Adenosine Triphosphate; Amide Synthases; Ammonia; Binding Sites; Glutamine; Kinetics; Models, Biological; Mutation; NAD; Substrate Specificity | 2006 |
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.
Topics: Adenosine Diphosphate Ribose; Amino Acids; Animals; Caloric Restriction; Cell Line, Tumor; Down-Regulation; Glucose; Glutamate Dehydrogenase; Glutamine; Humans; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Knockout; Mitochondria; NAD; Protein Processing, Post-Translational; RNA, Small Interfering; Sirtuin 1; Sirtuins; Transfection | 2006 |
The role of the invariant glutamate 95 in the catalytic site of Complex I from Escherichia coli.
Topics: Catalytic Domain; Electron Transport Complex I; Escherichia coli Proteins; Glutamine; Kinetics; Membrane Proteins; Models, Molecular; Mutation; NAD; Oxidation-Reduction; Protein Binding; Quinone Reductases | 2009 |
Regulation of active site coupling in glutamine-dependent NAD(+) synthetase.
Topics: Amide Synthases; Ammonia; Catalytic Domain; Crystallography, X-Ray; Glutamine; Kinetics; Models, Molecular; Mycobacterium tuberculosis; NAD; Protein Multimerization; Protein Structure, Quaternary; Protein Subunits | 2009 |
An ancestral glutamine-dependent NAD(+) synthetase revealed by poor kinetic synergism.
Topics: Amide Synthases; Amino Acid Sequence; Glutamine; Hot Temperature; Mycobacterium tuberculosis; NAD; Phylogeny; Saccharomyces cerevisiae; Thermotoga maritima | 2009 |
Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.
Topics: Acid-Base Equilibrium; Alanine; Amino Acid Substitution; Binding, Competitive; Catalysis; Catalytic Domain; Glutamic Acid; Glutamine; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NAD; Recombinant Proteins; Saccharomyces cerevisiae; Saccharopine Dehydrogenases | 2010 |
Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.
Topics: Analysis of Variance; Animals; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Guinea Pigs; Mice; Myelin Basic Protein; NAD; NADP; Nitric Oxide Synthase Type II; Oxidative Stress; Tandem Mass Spectrometry | 2011 |
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
Topics: Animals; Bilirubin; Cell Line; Cells, Cultured; Citric Acid Cycle; Computer Simulation; Fumarate Hydratase; Fumarates; Genes, Lethal; Genes, Tumor Suppressor; Glutamine; Heme; Heme Oxygenase (Decyclizing); Kidney Neoplasms; Leiomyomatosis; Mice; Mitochondria; Mutation; NAD; Neoplastic Syndromes, Hereditary; Skin Neoplasms; Uterine Neoplasms | 2011 |
Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.
Topics: Acetates; Cell Hypoxia; Cell Line, Tumor; Cells; Citric Acid; Citric Acid Cycle; Fatty Acids; Glutamine; Humans; Ketoglutaric Acids; Lactic Acid; Models, Biological; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase | 2013 |
The many faces of sirtuins: Sirtuins and the Warburg effect.
Topics: Antineoplastic Agents; Glutamine; Glycolysis; Humans; Longevity; Metabolic Networks and Pathways; Models, Biological; NAD; Neoplasms; Sirtuins | 2014 |
NADH-linked metabolic plasticity of MCF-7 breast cancer cells surviving in a nutrient-deprived microenvironment.
Topics: Female; Glutamine; Glycolysis; Humans; Lactic Acid; MCF-7 Cells; NAD; Starvation; Tumor Microenvironment | 2015 |
Improved biosynthesis of ethyl (S)-4-chloro-3-hydroxybutanoate by adding L-glutamine plus glycine instead of NAD+ in β-cyclodextrin-water system.
Topics: Acetoacetates; beta-Cyclodextrins; Butyrates; Escherichia coli; Glutamine; Glycine; NAD; Water | 2015 |
Secondary NAD+ deficiency in the inherited defect of glutamine synthetase.
Topics: Amino Acid Metabolism, Inborn Errors; B-Lymphocytes; Cell Culture Techniques; Dietary Supplements; Fibroblasts; Glutamate-Ammonia Ligase; Glutamine; Humans; Hyperammonemia; NAD; Point Mutation | 2015 |
In vitro characterization of the NAD+ synthetase NadE1 from Herbaspirillum seropedicae.
Topics: Amide Synthases; Chromatography, Gel; Glutamine; Herbaspirillum; Kinetics; NAD; Nitrogen | 2016 |
Structural insights into the catalytic reaction trigger and inhibition of D-3-hydroxybutyrate dehydrogenase.
Topics: 3-Hydroxybutyric Acid; Alcaligenes faecalis; Amino Acid Motifs; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Gene Expression; Glutamine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Hydroxybutyrate Dehydrogenase; Malonates; Methylmalonic Acid; Models, Molecular; NAD; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Subunits; Recombinant Proteins; Substrate Specificity; Tyrosine | 2016 |
Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable.
Topics: Biological Transport; Cell Line, Tumor; Enzyme Inhibitors; Glutamine; Humans; NAD; Nicotinamide Phosphoribosyltransferase; Oxidative Stress; Phosphorylation | 2016 |
Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC.
Topics: A549 Cells; Adenosine Triphosphate; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Death; Cell Proliferation; Cell Survival; Cytosol; Drug Synergism; Fluorouracil; Gene Knockdown Techniques; Glutamic Acid; Glutaminase; Glutamine; Lung Neoplasms; Malates; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; NAD; Oxidation-Reduction; Sulfides; Thiadiazoles; Thymidylate Synthase; Xenograft Model Antitumor Assays | 2016 |
Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Energy Metabolism; Gene Expression; Glucose; Glutamic Acid; Glutamine; Glycolysis; Heterografts; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lung Neoplasms; Mice; Mitochondria; Models, Biological; NAD; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species; Receptors, Metabotropic Glutamate; Riluzole | 2017 |
A New Step in the Treatment of Sickle Cell Disease
Topics: Amide Synthases; Ammonia; Anemia, Sickle Cell; Animals; Antisickling Agents; Drug Discovery; Glutaminase; Glutamine; Humans; NAD | 2018 |
NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction.
Topics: Bone Neoplasms; Cell Movement; Citric Acid Cycle; Cytosol; DNA, Mitochondrial; Energy Metabolism; Female; Glucose; Glutamine; Glycolysis; Humans; Malate Dehydrogenase; Mitochondria; NAD; Osteosarcoma; Oxidation-Reduction; Tumor Cells, Cultured | 2018 |
Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast.
Topics: Adipose Tissue, Brown; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Fatty Acids; Flavin-Adenine Dinucleotide; Fluorescence; Glutamine; Glycolysis; Humans; Imaging, Three-Dimensional; Metabolism; Mice; Mitochondria; Myocytes, Cardiac; NAD; Oxidation-Reduction | 2018 |
Kinetics and structural features of dimeric glutamine-dependent bacterial NAD
Topics: Adaptation, Physiological; Amide Synthases; Amino Acid Sequence; Ammonia; Azospirillum brasilense; Biological Evolution; Catalysis; Glutamine; Herbaspirillum; Kinetics; Mycobacterium tuberculosis; NAD; Phylogeny; Protein Multimerization; Sequence Homology, Amino Acid; Substrate Specificity | 2018 |
Fine-Tuning Mitochondrial Dysfunction and Reductive Carboxylation.
Topics: Glutamine; Glycolysis; Mitochondria; NAD; Oxidation-Reduction | 2018 |
Minimizing ATP depletion by oxygen scavengers for single-molecule fluorescence imaging in live cells.
Topics: Adenosine Triphosphate; Carbocyanines; Cell Line; Flavin-Adenine Dinucleotide; Fluorescence; Fluorescent Dyes; Glucose Oxidase; Glutamine; HEK293 Cells; Humans; Keto Acids; Microscopy, Fluorescence; Mitochondria; NAD; Oxygen; Phosphatidylinositol 4,5-Diphosphate; Photobleaching; Receptor, PAR-2 | 2018 |
Different ways to transport ammonia in human and Mycobacterium tuberculosis NAD
Topics: Amide Synthases; Ammonia; Bacterial Proteins; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Catalytic Domain; Glutaminase; Glutamine; Humans; Mycobacterium tuberculosis; NAD; Substrate Specificity | 2020 |
Microglial metabolic flexibility supports immune surveillance of the brain parenchyma.
Topics: Animals; Brain; Cell Movement; CX3C Chemokine Receptor 1; Energy Metabolism; Fatty Acids; Glucose; Glutamine; Immunologic Surveillance; Mice; Mice, Transgenic; Microglia; NAD; TOR Serine-Threonine Kinases | 2020 |
L-Glutamine in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Animals; Child; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Erythrocytes; Glutamine; Humans; Mice; NAD; Randomized Controlled Trials as Topic | 2020 |
α-ketobutyrate links alterations in cystine metabolism to glucose oxidation in mtDNA mutant cells.
Topics: Amino Acids; Butyrates; Carbon Isotopes; Cell Line; Cystine; DNA, Mitochondrial; Glucose; Glutamine; Humans; Mutation; NAD; Oxidation-Reduction; Oxygen Consumption | 2020 |
The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cyclic N-Oxides; Female; Glutamine; Glycolysis; Heterocyclic Compounds; Humans; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Docking Simulation; NAD; Neoplasms; Oxidative Phosphorylation; Pyruvic Acid; Reactive Oxygen Species; Serine; Spin Labels; Xenograft Model Antitumor Assays | 2020 |
Hydrogen sulfide stimulates lipid biogenesis from glutamine that is dependent on the mitochondrial NAD(P)H pool.
Topics: Energy Metabolism; Glutamine; Hydrogen Sulfide; Lipogenesis; Mitochondria; NAD; Signal Transduction | 2021 |
Metabolic plasticity drives development during mammalian embryogenesis.
Topics: Adaptation, Physiological; Animals; Blastocyst; Cells, Cultured; Citric Acid Cycle; Glucose; Glutamine; Metabolome; Mice; Mice, Inbred C57BL; NAD; Oxidation-Reduction; Transcriptome | 2021 |
The mTOR/PGC-1α/SIRT3 Pathway Drives Reductive Glutamine Metabolism to Reduce Oxidative Stress Caused by ISKNV in CPB Cells.
Topics: Animals; Cell Line; Fish Diseases; Fish Proteins; Glutaminase; Glutamine; Iridoviridae; NAD; Oxidative Stress; Perches; Phosphorylation; PPAR gamma; Signal Transduction; Sirtuin 3; TOR Serine-Threonine Kinases; Virus Replication | 2022 |
Rewired Cellular Metabolic Profiles in Response to Metformin under Different Oxygen and Nutrient Conditions.
Topics: Cell Line, Tumor; Cell Proliferation; Culture Media; Glucose; Glutamine; HeLa Cells; Humans; Lactic Acid; Metabolomics; Metformin; NAD; Oxygen; Pyruvic Acid; Tumor Hypoxia | 2022 |
Osmundacetone modulates mitochondrial metabolism in non-small cell lung cancer cells by hijacking the glutamine/glutamate/α-KG metabolic axis.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; G2 Phase Cell Cycle Checkpoints; Glutamic Acid; Glutamine; Humans; Ketones; Lung Neoplasms; Mice; Mitochondria; NAD | 2022 |
Effects of sugars, fatty acids and amino acids on cytosolic and mitochondrial hydrogen peroxide release from liver cells.
Topics: Adenosine Triphosphate; Amino Acids; Fatty Acids; Glucose; Glutamine; Hydrogen Peroxide; Liver; Mitochondria; NAD; NADPH Oxidases; Sugars; Superoxides | 2022 |
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Genes, Tumor Suppressor; Glutamine; Humans; Male; Mitochondrial Proteins; NAD; Prostatic Neoplasms; Sirtuins | 2022 |
In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors.
Topics: Animals; Electron Transport; Electron Transport Complex I; Glucose; Glutamine; Humans; Isotopes; Mice; NAD; Neoplasms; Saccharomyces cerevisiae Proteins | 2022 |
Reversible Glutamate Coordination to High-Valent Nickel Protects the Active Site of a [NiFe] Hydrogenase from Oxygen.
Topics: Alanine; Aspartic Acid; Catalytic Domain; Glutamic Acid; Glutamine; Hydrogenase; Hydrogenophilaceae; Iron; Ligands; NAD; Nickel; Oxidation-Reduction; Oxygen | 2022 |
Genome-wide identification of glutamate synthase gene family and expression patterns analysis in response to carbon and nitrogen treatment in Populus.
Topics: Carbon; Gene Expression Regulation, Plant; Glutamate Synthase; Glutamine; NAD; Nitrogen; Populus | 2023 |
NAD
Topics: Actinobacteria; Frankia; Glutamine; NAD; Nitrogen Fixation | 2023 |
Mitochondrial Uncoupling Inhibits Reductive Carboxylation in Cancer Cells.
Topics: Carcinoma, Renal Cell; Glutamine; Humans; Kidney Neoplasms; NAD | 2023 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |