nad has been researched along with glutamic acid in 252 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (23.02) | 18.7374 |
| 1990's | 74 (29.37) | 18.2507 |
| 2000's | 56 (22.22) | 29.6817 |
| 2010's | 50 (19.84) | 24.3611 |
| 2020's | 14 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Caucheteux, D; Hombroeckx, A; Hue, L; Pouleur, H; Veitch, K | 1 |
| Hirai, K; Ikeda, K; Wang, GY | 1 |
| Collier, RJ; Killeen, KP | 1 |
| Kim, H; Patel, MS | 1 |
| Baker, PJ; Britton, KL; Rice, DW; Rodgers, HF; Stillman, TJ | 1 |
| Arnold, MA; Wang, AJ | 1 |
| Berry, MN; Gregory, RB; Phillips, JW | 1 |
| Anderson, DH; Donald, LJ; Duckworth, HW; Jacob, MV | 1 |
| Ayoub, GS; Copenhagen, DR | 1 |
| Iga, K; Imon, H; Kadoya, F; Kataoka, K; Kubo, H; Mitani, A | 1 |
| Adler, L; Nilsson, A | 1 |
| Korpela, T; Kurkijärvi, K; Vierijoki, T | 1 |
| Ludden, PW; Lueddecke, BA; Woehle, DL | 1 |
| Aksamit, RR; Backlund, PS; Cantoni, GL; Date, T; Fujioka, M; Gomi, T; Takata, Y | 1 |
| Collier, RJ; Reich, KA; Weinstein, BR; Wilson, BA | 1 |
| Atlante, A; Passarella, S; Quagliariello, E | 1 |
| Graham, TE; Saltin, B | 1 |
| Kleinholz, M; Myers, RE; Wagner, KR | 1 |
| Méndez-Franco, J; Pérez-de la Mora, M; Riesgo-Escovar, JR; Salceda, R | 1 |
| Dregeris, IaIa; Kostova, SV; Levin, GS; Tremasova, GIa | 1 |
| Bell, ET; Bell, JE; LiMuti, C; Renz, CL | 1 |
| Heikkila, RE; Nicklas, WJ; Vyas, I | 1 |
| Barbieri, JT; Collier, RJ; Tweten, RK | 1 |
| Wright, G | 1 |
| Ramsay, RR; Salach, JI; Singer, TP | 1 |
| Rider, CC | 1 |
| Arai, T; Inouye, Y; Nakamura, S; Okada, H; Uno, J | 1 |
| Carroll, SF; Collier, RJ | 2 |
| Booth, RG; Johnson, EA; McKeown, KA; Ramsay, RR; Singer, TP | 1 |
| Chagoya de Sánchez, V; Díaz-Muñoz, M; Hernández-Muñoz, R | 1 |
| Bravo, C; Chávez, E; Jay, D | 1 |
| Balaban, RS; Koretsky, AP | 1 |
| Kanamori, K; Roberts, JD; Weiss, RL | 1 |
| Chang, TM; Ilan, E | 1 |
| Freter, M; Nyquist-Battie, C | 1 |
| Lochner, A; Potgieter, GM; van Jaarsveld, H | 1 |
| Baydoun, AR; Markham, A; Morgan, RM; Sweetman, AJ | 1 |
| Mickiewicz, W; Rzeczycki, W | 1 |
| Dousa, TP; Kempson, SA; Ou, SY | 1 |
| Borgatti, AR; Pagliarani, A; Trigari, G; Ventrella, V | 3 |
| White, HL | 1 |
| Berry, MN; Chalmers, AH; Mazzachi, RD | 1 |
| Hemmings, BA | 1 |
| Alonso, C; Caldés, T; Cañadas, S; González, MP; Ventura, ME | 1 |
| Makarewicz, W; Swierczyński, J | 1 |
| Caldas, RA; Carneiro, VT | 1 |
| Popova, SV; Reich, JG | 1 |
| Ashour, B; Hansford, RG | 1 |
| Lehninger, AL; Moreadith, RW | 1 |
| Dennig, G; Sieghart, W | 1 |
| Engel, PC; Hornby, DP | 1 |
| Aitchison, MJ; Engel, PC; Hornby, DP | 1 |
| Cazzulo, JJ | 1 |
| Barletta, A; Iossa, S; Lionetti, L; Liverini, G; Mollica, MP | 1 |
| Conejero, C; Galarreta, M; Martín del Río, R; Menéndez, N; Solís, JM | 1 |
| Engel, PC; Wang, XG | 1 |
| Ishizaki, T; Morii, N; Narumiya, S; Nemoto, Y; Saito, Y; Watanabe, N | 1 |
| Burlakova, EB; Kaplan, EIa; Khristianovich, DS; Pakhomov, VIu; Rozantseva, TV; Voronkov, MG; Zhigacheva, IV | 1 |
| Böhm, G; Jaenicke, R; Tomschy, A | 1 |
| Hussain, AN; Ishaq, M; Javed, MU; Waqar, MA; Yousuf, FA | 1 |
| Wang, X; Weiner, H | 1 |
| Basso, LA; Engel, PC; Walmsley, AR | 3 |
| Baker, PJ; Britton, KL; Dean, JL; Engel, PC; Rice, DW; Stillman, TJ; Wang, XG | 1 |
| Alldread, RM; Atkinson, T; Clarke, AR; Halsall, DM; Nicholls, DJ; Scawen, MD; Sundaram, TK | 1 |
| Panov, AV; Scaduto, RC | 1 |
| Faraone-Mennella, MR; Farina, B | 1 |
| Boles, E; Lehnert, W; Zimmermann, FK | 1 |
| Atlante, A; Passarella, S; Pierro, P; Quagliariello, E | 1 |
| Cunningham, SJ; Farrés, J; Takahashi, K; Wang, TT; Wang, X; Weiner, H | 1 |
| Scaduto, RC | 1 |
| Tsuru, N; Ueda, Y | 1 |
| Colman, RF; Wrzeszczynski, KO | 1 |
| Brucklacher, RM; Vannucci, RC | 1 |
| Lange, KW; Riederer, P; Youdim, MB | 1 |
| Kato, Y; Ogawa, HI; Rui, CS; Sonomoto, K | 1 |
| Bachelard, HS; Badar-Goffer, RS; Ben-Yoseph, O; Morris, PG | 1 |
| Haselbeck, RJ; McAlister-Henn, L | 1 |
| Hatefi, Y; Yamaguchi, M | 1 |
| Outlaw, WH | 1 |
| Aktories, K; Hofmann, F; Jung, M; Just, I; van Damme, J; Vandekerckhove, J | 1 |
| Jahns, T | 1 |
| Kuraishi, Y; Tohda, C | 1 |
| Sligar, SG; Yeom, H | 1 |
| Poitry, S; Poitry-Yamate, CL; Tsacopoulos, M | 1 |
| Iwasa, T; Kikkawa, S; Nakagawa, M; Tsuda, M | 1 |
| Crawford, JH; Scott, RH; Seabrook, GR; Wootton, JF | 1 |
| Hurley, TD; Steinmetz, CG; Weiner, H; Xie, P | 1 |
| Meighen, E; Vedadi, M | 1 |
| Akiyama, DS; Niihara, Y; Tanaka, KR; Zerez, CR | 1 |
| Boon, L; Charles, R; Geerts, WJ; Jonker, A; Lamers, WH; Meijer, AJ; Van Noorden, CJ | 1 |
| Perrottet, P; Poitry, S; Poitry-Yamate, CL; Tsacopoulos, M; Veuthey, AL | 1 |
| Peterson, PE; Pierce, J; Smith, TJ | 1 |
| Aghajanian, S; Engel, PC; Goyal, A; Hayden, BM; Wang, XG | 1 |
| Matsuzawa, H; Ohta, T; Taguchi, H | 1 |
| Bonilla, AC; del Arenal Mena, IP; Escamilla, JE; Moreno-Sánchez, R | 1 |
| Cocaign-Bousquet, M; Dominguez, H; Guerquin-Kern, JL; Guyonvarch, A; Lindley, ND; Rollin, C | 1 |
| Aoki, M; Ishimori, K; Morishima, I | 1 |
| Ayoub, GS; Grutsis, S; Simko, H | 1 |
| Balaban, RS; French, SA; Territo, PR | 1 |
| Dryjanski, M; Kosley, LL; Pietruszko, R | 1 |
| Bartolucci, S; Cannio, R; Fiorentino, G; Rossi, M | 1 |
| Hong, YS; Korotchkina, LG; Liu, TC; Patel, MS; Vettakkorumakankav, NN | 1 |
| Joshi, NB; Kannurpatti, SS | 1 |
| Baker, EN; Baker, HM; Blythe, TJ; Kitson, KE; Kitson, TM; Moore, SA | 1 |
| Hurley, TD; Weiner, H | 1 |
| Atlante, A; Calissano, P; Gagliardi, S; Marra, E; Passarella, S | 1 |
| Glowinski, J; Israël, M; Mailly, F; Marin, P; Prémont, J | 1 |
| Dodzin, ME; Vinogradova, KA | 1 |
| Mann, CJ; Weiner, H | 1 |
| Blackshaw, S; Brat, DJ; Clements, EE; Conover, JR; Favit, A; Krug, DK; Pieper, AA; Pinto-Garcia, P; Snyder, SH; Verma, A; White, AJ | 1 |
| Haydon, PG; Innocenti, B; Parpura, V | 1 |
| Ishihara, H; Wollheim, CB | 1 |
| Gourdon, P; Lindley, ND | 1 |
| Armero, JM; Arriagada, C; Caviedes, P; Caviedes, R; Dagnino-Subiabre, A; Segura-Aguilar, J | 1 |
| Weiner, H; Zhou, J | 1 |
| Adam-Vizi, V; Tretter, L | 1 |
| Abdelal, AT; Lu, CD | 1 |
| Alvarez-Gonzalez, R; Chavez-Bueno, S; Mendoza-Alvarez, H | 1 |
| Engel, PC; Hayden, BM | 1 |
| Fang, J; Peterson, PE; Schmidt, T; Smith, TJ; Stanley, CA | 1 |
| Lang, HJ; Obrosova, IG; Stevens, MJ | 1 |
| Almeida, A; Bolaños, JP | 1 |
| Ballou, DP; Ludwig, ML; Matthews, RG; Trimmer, EE | 1 |
| Asada, H; Hiroto, M; Inada, Y; Itoh, T; Kodera, Y; Matsushima, A; Nishimura, H | 1 |
| Bruzzone, S; De Flora, A; Fedele, E; Matteoli, M; Schenk, U; Verderio, C; Zocchi, E | 1 |
| Reynolds, IJ; Votyakova, TV | 1 |
| Breazeale, SD; Raetz, CR; Ribeiro, AA | 1 |
| Griffiths, EJ; King, N; Suleiman, MS; Williams, H | 1 |
| Fukami, TA; Nakamori, S; Shimizu, S; Shiratori, Y; Sogabe, S; Takagi, H; Wada, M; Yoshizumi, A | 1 |
| Burke, NA; Carcillo, JA; Clark, RS; Du, L; Graham, SH; Han, YY; Kochanek, PM; Szabó, C; Watkins, SC; Zhang, X | 1 |
| Brennan, AM; Connor, JA; Shuttleworth, CW | 1 |
| Meijer, AJ | 1 |
| Bieganowski, P; Brenner, C | 1 |
| Bonete, MJ; Díaz, S; Ferrer, J; Oren, A; Pérez-Pomares, F | 1 |
| HOLZER, H; SOELING, HD | 1 |
| GILLES, R; SCHOFFENIELS, E | 1 |
| ADAMS, E; GOLDSTONE, A | 1 |
| SLATER, EC; TAGER, JM | 3 |
| TAGER, JM | 1 |
| HOWLAND, JL; SLATER, EC; SNOSWELL, AM; TAGER, JM | 1 |
| HIRD, FJ; MARGINSON, MA | 1 |
| AYLING, JE; BALTIMORE, BG; KUN, E | 1 |
| BURCHALL, JJ; NIEDERMAN, RA; WOLIN, MJ | 1 |
| DURAND, R; GAUDEMER, Y; GAUTHERON, D; PIALOUX, N | 1 |
| ORMSBEE, RA; PEACOCK, MG | 1 |
| ADELSTEIN, SJ | 1 |
| BALAZS, R | 1 |
| FRANCAVILLA, A; PALMIERI, F; PAPA, S; QUAGLIARIELLO, E; SACCONE, C | 1 |
| GUTFREUND, H; JONES, EA | 1 |
| Joshi, NB; Joshi, PG; Kannurpatti, SS; Mishra, S; Sanganahalli, BG | 1 |
| Kudej, RK; LaNoue, KF; Lewandowski, ED; O'Donnell, JM; Vatner, SF | 1 |
| Gu, Y; Qhobosheane, M; Tan, W; Wu, D | 1 |
| Gadre, R; Jain, M | 1 |
| Kunz, WS; Wallesch, CW; Wiedemann, FR; Winkler-Stuck, K | 1 |
| Fushinobu, S; Shoun, H; Su, F; Takaya, N | 1 |
| Hille, R; Igarashi, K; Leimkühler, S; Nishino, T; Stockert, AL | 1 |
| Halliwell, B; Vincent, AS; Wong, KP; Zhang, X | 1 |
| Achilli, A; Barbiroli, B; Barboni, P; Baruzzi, A; Bucchi, L; Carelli, V; Dotti, M; Federico, A; Ghelli, A; Lodi, R; Lugaresi, A; Rengo, C; Torroni, A; Valentino, ML | 1 |
| Contreras-Shannon, V; Lin, AP; McAlister-Henn, L; McCammon, MT | 1 |
| Banerjee, S; Ray, M; Ray, S; SinhaRoy, S | 1 |
| Hurley, TD; Larson, HN; Weiner, H | 1 |
| Ashida, H; Ishikawa, T; Ito, K; Khan, MI; Kim, H; Sawa, Y; Shibata, H | 1 |
| Inagaki, E; Kuroishi, C; Tahirov, TH; Takahashi, H | 1 |
| Wang, S; Yu, H | 1 |
| Aliverti, A; Coda, A; de Rosa, M; Mattevi, A; Pandini, V; Pennati, A; Razeto, A; Vanoni, MA; Zanetti, G | 1 |
| Graeff, R; Hao, Q; Kriksunov, IA; Lee, HC; Liu, Q; Munshi, C | 1 |
| Contreras, L; Gomez-Puertas, P; Iijima, M; Kobayashi, K; Saheki, T; Satrústegui, J | 1 |
| Davis, L; Kim, DY; Maalouf, M; Rho, JM; Sullivan, PG | 1 |
| Hellmer, H; Klimacek, M; Nidetzky, B | 1 |
| Kawakami, R; Ohshima, T; Sakuraba, H | 1 |
| Abdul-Ghani, MA; Bhattacharya, A; Jang, YC; Liu, Y; Lustgarten, MS; Muller, FL; Van Remmen, H | 1 |
| Howarth, C; Hyder, F; Riera, JJ; Schousboe, A; Waagepetersen, HS | 1 |
| Boquet, P; Flatau, G; Ménétrey, J; Ménez, A; Stura, EA | 1 |
| Cai, C; Chen, G; Meng, L; Sun, Y; Wu, P; Yuan, Z | 1 |
| Baeg, JO; Kale, BB; Lee, SH; Lee, SM; Park, CB; Subramanian, E | 1 |
| Liu, W; Wang, P; Zhang, S | 1 |
| Rahman, MM; Sawada, K; Umar, A | 1 |
| Bolognesi, M; Corda, D; Luini, A; Nardini, M; Ricagno, S; Valente, C | 1 |
| Lund, TM; Risa, O; Schousboe, A; Sonnewald, U; Waagepetersen, HS | 1 |
| Lee, SH; Park, CB; Song, HK; Won, K | 1 |
| Fülöp, F; Klivényi, P; Toldi, J; Vámos, E; Vécsei, L; Zádori, D | 1 |
| Alano, CC; Anderson, CM; Hunt, WT; Shao, Z; Suh, SW; Swanson, RA; Tang, KS | 1 |
| Brun, T; Casimir, M; Frigerio, F; Li, N; Maechler, P; Vetterli, L | 1 |
| Kawakami, R; Ohshima, T; Oyama, M; Sakuraba, H | 1 |
| Andi, B; Bobyk, KD; Cook, PF; Ekanayake, DK; West, AH | 1 |
| Harper, CJ; Hayward, D; Kidd, M; van Helden, P; Wiid, I | 1 |
| Chiriac, M; Lupan, I; Palibroda, N; Popa, F; Popescu, O | 1 |
| Dang, VU; Luu, BV; Nguyen, MH | 1 |
| Cai, L; Li, H; Li, L; Liu, S; Xie, Y; Yang, X | 1 |
| Fujii, T; Kitazume, T; Masuo, S; Shimizu, M; Takaya, N; Terabayashi, Y | 1 |
| Barkhouse, DA; Castegna, A; Curtis, MT; Fabis-Pedrini, MJ; Hooper, DC; Kean, RB; Palmieri, F; Palmieri, L; Porcelli, V; Spera, I | 1 |
| Halámek, J; Katz, E; Valdés-Ramírez, G; Wang, J; Windmiller, JR; Zhou, M; Zhou, N | 1 |
| Bland, RJ; Knight, JS; Patchett, ML; Simpson, HV; Umair, S | 1 |
| Bi, J; Ding, S; Li, H; Ye, SQ | 1 |
| Lee, JK; Liu, D; Tao, Y; Yan, X; Yang, C; Zhou, Z | 1 |
| Galeffi, F; Turner, DA | 1 |
| Do, PM; Govindasamy, L; Ingram, LO; Rhee, MS; Shanmugam, KT; Sun, Z; Wang, Q | 1 |
| Giaume, C; Orellana, JA; Sáez, JC; von Bernhardi, R | 1 |
| Nam, DH; Park, CB | 1 |
| Bol, M; Bukauskas, FF; Bultynck, G; De Bock, M; Decrock, E; Gadicherla, A; Leybaert, L; Rogiers, V; Vinken, M; Wang, N | 1 |
| Bresser, J; Buckel, W; Djurdjevic, I; Engel, PC; Schall, I; Wang, X; Yu, X | 1 |
| Hertz, L; Li, B; Peng, L | 1 |
| Kao, MC; Matsuno-Yagi, A; Patki, G; Sato, M; Sinha, PK; Torres-Bacete, J; Yagi, T | 1 |
| Bouton, S; Dubois, F; Fontaine, JX; Hirel, B; Lea, PJ; Pageau, K; Tercé-Laforgue, T | 1 |
| Deshpande, MV; Joshi, CV; Kapadnis, BP; Pathan, EK; Punekar, NS; Tupe, SG | 1 |
| Bratus', LV; Koliesnikova, IeE; Nosar, VI | 1 |
| Belevich, G; Bloch, DA; Knuuti, J; Sharma, V; Verkhovskaya, M | 1 |
| Hao, P; Ji, X; Liang, Z; Liu, J; Liu, R; Liu, Y; Piao, H; Wang, Y | 1 |
| Grigg, JC; Heinrichs, DE; Kobylarz, MJ; Murphy, ME; Rai, DK; Takayama, SJ | 1 |
| Echandi, MP; Ellerbrock, J; Fedkenheuer, M; Franceschini, S; Martin Del Campo, JS; Robinson, R; Rodriguez, PJ; Romero, E; Sobrado, P | 1 |
| Kim, JH; Lee, SH; Nam, DH; Park, CB; Ryu, GM | 1 |
| Ding, S; Li, H; Wang, X | 1 |
| González-Segura, L; Julián-Sánchez, A; Muñoz-Clares, RA; Riveros-Rosas, H | 1 |
| Borisova, T; Borуsov, A; Krisanova, N; Kucherenko, D; Kucherenko, I; Nazarova, A; Pozdnyakova, N; Soldatkin, A; Soldatkin, O | 1 |
| Anita, A; Kalaivani, P; Pramila, B; Saravana Babu, C | 1 |
| Chen, J; Fernandez, J; Fernandez-Bueno, GA; Gusdon, AM; Mathews, CE; Wohlgemuth, S | 1 |
| Brun, T; Maechler, P | 1 |
| Calmettes, G; Korge, P; Weiss, JN | 1 |
| Amoedo, ND; De Grassi, A; Lacombe, D; Obre, E; Pierri, CL; Punzi, G; Rossignol, R | 1 |
| Guevara-Martínez, M; Gustavsson, M; Jarmander, J; Larsson, G; Perez-Zabaleta, M; Quillaguamán, J; Sjöberg, G | 1 |
| Gelman, SJ; Mahieu, NG; Patti, GJ; Spalding, JL | 1 |
| Smith, HQ; Smith, TJ | 1 |
| Hong, D; Hong, KM; Kang, JH; Kim, SY; Lee, JS; Lee, SH; Son, J; Song, J | 1 |
| Chen, Z; Huang, J; Liu, D; Wu, W; Wu, Y; Zhang, Y | 1 |
| Palmer, DR; Vetter, ND | 1 |
| Beamer, LJ; Becker, DF; Christgen, S; Gamage, TT; Henzl, MT; Korasick, DA; Stiers, KM; Tanner, JJ | 1 |
| Chen, S; Feun, LG; Kandemir, H; Kuo, MT; Li, YY; Nguyen, DJM; Prince, JS; Savaraj, N; Shah, S; Wangpaichitr, M; Wu, C | 1 |
| Archer, M; Athayde, D; Batista, AP; Brito, JA; Catarino, T; Oliveira, ASF; Pereira, MM; Sena, FV; Soares, CM; Sousa, FM | 1 |
| Carvajal, F; Garrido, D; Jamilena, M; Jiménez-Muñoz, R; Palma, F; Pulido, A | 1 |
| Anderson, RG; Chung, EH; Dangl, JL; DiAntonio, A; Essuman, K; Milbrandt, J; Monteiro, F; Nishimura, MT; Osborne Nishimura, E; Sasaki, Y; Wan, L | 1 |
| Fei, Z; Jing, Z; Lijuan, Y; Shuwen, H; Xi, Y; Yuefen, P | 1 |
| Gao, J; Zhang, YW; Zhou, Q | 1 |
| But, SY; Khmelenina, VN; Mustakhimov, II; Reshetnikov, AS; Rozova, ON | 1 |
| Belosludtsev, KN; Belosludtseva, NV; Khunderyakova, NV; Kireeva, TA; Mironova, GD | 1 |
| Gunn, B; Keniry, M; Litif, C; Lopez, A; Schuenzel, E; Udawant, S | 1 |
| Ahmad, B; Azizullah, A; Faheem, M; Israr, M; Raza, M; Sun, X; Tariq, M; Ur Rehman, S; Yuan, Q | 1 |
| He, P; Hou, Y; Li, N; Liu, Z; Yang, Y; Zhang, X | 1 |
| Chen, J; Huang, X; Huang, Z; Wang, L; Yang, C; Zhao, G | 1 |
| Amaral, AU; Marschner, RA; Ribeiro, RT; Roginski, AC; Wajner, M; Wajner, SM; Zemniaçak, ÂB | 1 |
| Bernitzky, CCM; Greetham, GM; Higuchi, Y; Horch, M; Hunt, NT; Ishii, M; Karafoulidi-Retsou, C; Kulka-Peschke, CJ; Lauterbach, L; Lenz, O; Lorent, C; Matsuura, H; Preissler, J; Procacci, B; Rippers, Y; Schulz, AC; Schulz, C; Teutloff, C; Wahlefeld, S; Wiemann, C; Wrathall, SLD; Zebger, I | 1 |
| Fiedler, M; Pfanzelt, M; Ranava, D; Scheidler, CM; Schneider, S; Sieber, SA; Yap, MF | 1 |
| Blixt, J; Gunnarson, E; Song, Y; Wanecek, M | 1 |
| Grzechowiak, M; Jaskolski, M; Ruszkowski, M; Sliwiak, J | 1 |
| Kataoka, N; Matsushita, K; Yakushi, T | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
13 review(s) available for nad and glutamic acid
| Article | Year |
|---|---|
Protein and amino acid catabolism in Trypanosoma cruzi.
Topics: Amino Acids; Animals; Cell-Free System; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Kinetics; NAD; Peptide Hydrolases; Proteins; Transaminases; Trypanosoma cruzi | 1984 |
Recent advances in pharmacological therapy of Parkinson's disease.
Topics: Antiparkinson Agents; Dopamine Agents; Droxidopa; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Levodopa; NAD; Neurologic Examination; Parkinson Disease; Receptors, Dopamine | 1993 |
[Streptomyces L-glutamate oxidase: use in clinical and fundamental medicine].
Topics: Amino Acid Oxidoreductases; Ammonia; Animals; Aspartate Aminotransferases; Biosensing Techniques; Central Nervous System; Creatinine; Glutamic Acid; Glutamine; Humans; Magnesium; Mammals; NAD; NADP; Streptomyces; Urea | 1999 |
What couples glycolysis to mitochondrial signal generation in glucose-stimulated insulin secretion?
Topics: Adenosine Triphosphate; Animals; Carrier Proteins; Cell Line; Cells, Cultured; Glucose; Glutamic Acid; Glycolysis; Humans; Insulin; Insulin Secretion; L-Lactate Dehydrogenase; Mice; Mitochondria; Models, Biological; Monocarboxylic Acid Transporters; NAD; Pyruvic Acid; Rats; Signal Transduction | 2000 |
Amino acids as regulators and components of nonproteinogenic pathways.
Topics: Amino Acids; Animals; Aspartic Acid; Cell Size; Glutamic Acid; Humans; Insulin; Islets of Langerhans; Metabolism; NAD; Oxidation-Reduction; Signal Transduction; Urea | 2003 |
The micro-architecture of the cerebral cortex: functional neuroimaging models and metabolism.
Topics: Animals; Cerebral Cortex; Citric Acid Cycle; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycolysis; Humans; Lactates; Models, Neurological; Models, Statistical; NAD; Oxidative Phosphorylation | 2008 |
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies.
Topics: Animals; Brain; Glutamic Acid; Humans; Kynurenic Acid; Mitochondrial Diseases; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolinic Acid; Tryptophan | 2009 |
Role of mitochondria in beta-cell function and dysfunction.
Topics: Adenosine Triphosphate; Animals; Diabetes Mellitus; Fatty Acids; Glucose; Glutamate Dehydrogenase; Glutamic Acid; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mitochondria; Models, Biological; NAD; Reactive Oxygen Species | 2010 |
Exploiting metabolic differences in glioma therapy.
Topics: Brain Neoplasms; Glioma; Glutamic Acid; Glutamine; Humans; Hypoxia-Inducible Factor 1; NAD; NADP; Signal Transduction | 2012 |
Glial hemichannels and their involvement in aging and neurodegenerative diseases.
Topics: Adenosine Triphosphate; Aging; Astrocytes; Calcium; Cannabinoids; Central Nervous System; Connexin 43; Connexins; Dinoprostone; Glucose; Glutamic Acid; Humans; Inflammation; Interleukin-1beta; Ion Channels; NAD; Nerve Degeneration; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Oligodendroglia; Signal Transduction; Tumor Necrosis Factor-alpha | 2012 |
Paracrine signaling through plasma membrane hemichannels.
Topics: Adenosine Triphosphate; Animals; Cell Membrane; Connexin 26; Connexins; Dinoprostone; Glutamic Acid; Glutathione; Humans; Membrane Potentials; NAD; Paracrine Communication; Protein Processing, Post-Translational | 2013 |
Beta-cell mitochondrial carriers and the diabetogenic stress response.
Topics: Animals; Citric Acid Cycle; Diabetes Mellitus, Type 2; Exocytosis; Fatty Acids; Glucose; Glutamic Acid; Homeostasis; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mammals; Mitochondria; Mitochondrial Membrane Transport Proteins; NAD; Oxidative Stress; Signal Transduction | 2016 |
AGC1/2, the mitochondrial aspartate-glutamate carriers.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Biological Transport, Active; Calcium-Binding Proteins; Cattle; Consensus Sequence; Glutamic Acid; Humans; Malates; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Models, Molecular; NAD; Neoplasm Proteins; Organ Specificity; Organic Anion Transporters; Oxidation-Reduction; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid | 2016 |
239 other study(ies) available for nad and glutamic acid
| Article | Year |
|---|---|
Global ischaemia induces a biphasic response of the mitochondrial respiratory chain. Anoxic pre-perfusion protects against ischaemic damage.
Topics: Animals; Buffers; Coronary Disease; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Glutamates; Glutamic Acid; Kinetics; Malates; Male; Mitochondria, Heart; Multienzyme Complexes; Myocardial Reperfusion Injury; NAD; NAD(P)H Dehydrogenase (Quinone); NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxidoreductases; Oxygen; Oxygen Consumption; Rats; Rats, Inbred Strains; Succinate Dehydrogenase; Time Factors | 1992 |
Paraquat damage of rat liver mitochondria by superoxide production depends on extramitochondrial NADH.
Topics: Animals; Benzoquinones; Cytochrome c Group; Free Radicals; Glucose-6-Phosphatase; Glutamates; Glutamic Acid; Malates; Male; Mice; Mice, Inbred ICR; Microscopy, Electron; Mitochondria, Liver; NAD; NADP; Paraquat; Rats; Rats, Inbred Strains; Rotenone; Superoxide Dismutase; Superoxides | 1992 |
Conformational integrity of a recombinant toxoid of Pseudomonas aeruginosa exotoxin A containing a deletion of glutamic acid-553.
Topics: ADP Ribose Transferases; Bacterial Toxins; Binding Sites; Calorimetry, Differential Scanning; Chromosome Deletion; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Exotoxins; Glutamates; Glutamic Acid; NAD; Poly(ADP-ribose) Polymerases; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Spectrometry, Fluorescence; Toxoids; Virulence Factors | 1992 |
Characterization of two site-specifically mutated human dihydrolipoamide dehydrogenases (His-452----Gln and Glu-457----Gln).
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Dihydrolipoamide Dehydrogenase; Escherichia coli; Flavin-Adenine Dinucleotide; Genetic Vectors; Glutamates; Glutamic Acid; Glutamine; Histidine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligodeoxyribonucleotides; Protein Conformation; Recombinant Proteins | 1992 |
Effect of additives on the crystallization of glutamate dehydrogenase from Clostridium symbiosum. Evidence for a ligand-induced conformational change.
Topics: Clostridium; Crystallography; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ligands; NAD; Protein Conformation; Structure-Activity Relationship | 1992 |
Dual-enzyme fiber-optic biosensor for glutamate based on reduced nicotinamide adenine dinucleotide luminescence.
Topics: Biosensing Techniques; Glutamates; Glutamic Acid; Luminescent Measurements; NAD | 1992 |
Reducing-equivalent transfer to the mitochondria during gluconeogenesis and ureogenesis in hepatocytes from rats of different thyroid status.
Topics: Alanine; Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Cytoplasm; Gluconeogenesis; Glutamates; Glutamic Acid; Hydrogen; Hyperthyroidism; Hypothyroidism; Male; Malonates; Mitochondria, Liver; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Thyroid Gland; Urea | 1992 |
A mutant of Escherichia coli citrate synthase that affects the allosteric equilibrium.
Topics: Allosteric Regulation; Arginine; Citrate (si)-Synthase; Coenzyme A; Escherichia coli; Glutamates; Glutamic Acid; Kinetics; Leucine; Mutagenesis, Site-Directed; Mutation; NAD; Oxaloacetates; Protein Conformation; Spectrophotometry, Ultraviolet | 1991 |
Application of a fluorometric method to measure glutamate release from single retinal photoreceptors.
Topics: Animals; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Lizards; NAD; Peptides; Photic Stimulation; Photoreceptor Cells; Retina; Spectrometry, Fluorescence | 1991 |
A new enzymatic cycling technique for glutamate determination in brain microdialysates.
Topics: Animals; Brain; Brain Ischemia; Dialysis; Extracellular Space; Gerbillinae; Glutamates; Glutamic Acid; Hippocampus; Male; NAD; Time Factors | 1990 |
Purification and characterization of glycerol-3-phosphate dehydrogenase (NAD+) in the salt-tolerant yeast Debaryomyces hansenii.
Topics: Cations; Chromatography; Drug Tolerance; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glutamates; Glutamic Acid; Glycerol; Glycerolphosphate Dehydrogenase; Hydrogen-Ion Concentration; Kinetics; Magnesium; Molecular Weight; NAD; Osmolar Concentration; Potassium; Saccharomycetales; Salts; Substrate Specificity | 1990 |
Flow-injection analysis of amino acids and their metabolites by immobilized vitamin B6-dependent enzymes. Sensitive determination of L-aspartate, L-glutamate, 2-oxoglutarate, and oxaloacetate.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Cattle; Enzymes, Immobilized; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Luminescent Measurements; Malate Dehydrogenase; NAD; Oxaloacetates; Pyridoxine | 1990 |
ATP-dependent and NAD-dependent modification of glutamine synthetase from Rhodospirillum rubrum in vitro.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Immune Sera; Immunoblotting; Kinetics; Malates; Molecular Sequence Data; NAD; Peptide Fragments; Phosphorus Radioisotopes; Rhodospirillum rubrum | 1990 |
Site-directed mutagenesis of rat liver S-adenosylhomocysteinase. Effect of conversion of aspartic acid 244 to glutamic acid on coenzyme binding.
Topics: Adenosylhomocysteinase; Apoenzymes; Aspartic Acid; Base Sequence; Binding Sites; Cloning, Molecular; Escherichia coli; Glutamates; Glutamic Acid; Hydrolases; Kinetics; Liver; Molecular Sequence Data; Molecular Weight; Mutation; NAD; Oligonucleotide Probes; Recombinant Proteins | 1990 |
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
Topics: Adenosine Diphosphate Ribose; Affinity Labels; Aspartic Acid; Base Sequence; Binding Sites; Diphtheria Toxin; Glutamates; Glutamic Acid; Glutamine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Serine; Substrate Specificity | 1990 |
Metabolite transport in rat kidney mitochondria: ornithine/phosphate translocator.
Topics: Animals; Biological Transport; Carrier Proteins; Fluorometry; Glutamates; Glutamic Acid; Kidney; Kinetics; Malates; Male; Membrane Transport Proteins; Mersalyl; Mitochondria; NAD; NADP; Ornithine; Oxidation-Reduction; Phosphates; Praseodymium; Rats; Rats, Inbred Strains; Spectrophotometry | 1989 |
Estimation of the mitochondrial redox state in human skeletal muscle during exercise.
Topics: Adult; Ammonia; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Humans; Ketoglutaric Acids; Lactates; Lactic Acid; Male; Mitochondria, Muscle; NAD; Oxidation-Reduction; Oxygen Consumption; Physical Exertion | 1989 |
Delayed neurologic deterioration following anoxia: brain mitochondrial and metabolic correlates.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Brain; Carbon Dioxide; Cats; Cytochrome b Group; Female; Flavin-Adenine Dinucleotide; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic Acid; Male; Mitochondria; NAD; Organ Size; Oxygen; Oxygen Consumption; Phosphocreatine; Succinates; Succinic Acid | 1989 |
A glutamate dehydrogenase-based method for the assay of L-glutamic acid: formation of pyridine nucleotide fluorescent derivatives.
Topics: Animals; Brain Chemistry; Cattle; Fluorescent Dyes; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Hydrazines; Hydrogen Peroxide; Methods; NAD; Ornithine-Oxo-Acid Transaminase; Oxidation-Reduction; Rats; Sodium Hydroxide | 1989 |
[The mechanism of action of a synthetic derivative of 1,4-naphthoquinone on the respiratory chain of liver and heart mitochondria].
Topics: Animals; Antimycin A; Catalysis; Cyanides; Cytochromes b5; Electron Transport; Glutamates; Glutamic Acid; Male; Mitochondria, Heart; Mitochondria, Liver; NAD; Naphthoquinones; Oxidation-Reduction; Oxygen Consumption; Rabbits; Rats; Rotenone; Succinate Dehydrogenase | 1989 |
Negative co-operativity in glutamate dehydrogenase. Involvement of the 2-position in glutamate in the induction of conformational changes.
Topics: Binding Sites; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutarates; Kinetics; Ligands; NAD; Oxidation-Reduction; Protein Conformation; Spectrometry, Fluorescence | 1985 |
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Diphosphate; Animals; Brain; Glutamates; Glutamic Acid; Malates; Male; Mice; Mitochondria; NAD; Neurotoxins; Oxidation-Reduction; Phosphorylation; Pyridines; Rats; Rats, Inbred Strains | 1985 |
Diphtheria toxin. Effect of substituting aspartic acid for glutamic acid 148 on ADP-ribosyltransferase activity.
Topics: Aspartic Acid; Base Sequence; Binding Sites; Cloning, Molecular; Corynebacterium diphtheriae; Diphtheria Toxin; Escherichia coli; Genes; Genes, Bacterial; Glutamates; Glutamic Acid; Mutation; NAD; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Protein Binding | 1985 |
Amino acids in the treatment of ischaemic heart disease.
Topics: Amino Acids; Animals; Coronary Disease; Energy Metabolism; Glucose; Glutamates; Glutamic Acid; Humans; L-Lactate Dehydrogenase; Muscles; Myocardium; NAD; Oxidation-Reduction; Phosphorylation | 1985 |
Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport, Active; Electron Transport; Glutamates; Glutamic Acid; Intracellular Membranes; Malates; Mitochondria, Heart; Mitochondria, Liver; NAD; NAD(P)H Dehydrogenase (Quinone); Pyridinium Compounds; Quinone Reductases; Rats; Succinates; Succinic Acid | 1986 |
Apparent inhibition of ATP citrate lyase by L-glutamate in vitro is due to the presence of glutamine synthetase.
Topics: Adenosine Triphosphate; Animals; ATP Citrate (pro-S)-Lyase; Brain; Chromatography, Affinity; Chromatography, Gel; Citrates; Citric Acid; Female; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Liver; Malate Dehydrogenase; Methionine Sulfoximine; NAD; Rats; Rats, Inbred Strains | 1986 |
Effects of streptonigrin derivatives and sakyomicin A on the respiration of isolated rat liver mitochondria.
Topics: Animals; Anti-Bacterial Agents; Benzoquinones; Edetic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Quinone Reductases; Quinones; Rats; Streptonigrin | 1986 |
Active site of Pseudomonas aeruginosa exotoxin A. Glutamic acid 553 is photolabeled by NAD and shows functional homology with glutamic acid 148 of diphtheria toxin.
Topics: ADP Ribose Transferases; Affinity Labels; Bacterial Toxins; Diphtheria Toxin; Exotoxins; Glutamates; Glutamic Acid; Molecular Weight; NAD; Photolysis; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Sequence Homology, Nucleic Acid; Ultraviolet Rays; Virulence Factors | 1987 |
Inhibition of NADH oxidation by pyridine derivatives.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Cytochrome Reductases; Glutamates; Glutamic Acid; Intracellular Membranes; Mitochondria, Heart; Mitochondria, Liver; NAD; NADH Dehydrogenase; Oxidation-Reduction; Oxygen Consumption; Pyridines; Pyridinium Compounds; Rats; Structure-Activity Relationship | 1987 |
In vivo and in vitro adenosine stimulation of ethanol oxidation by hepatocytes, and the role of the malate-aspartate shuttle.
Topics: Adenosine; Animals; Aspartic Acid; Ethanol; Glutamates; Glutamic Acid; In Vitro Techniques; Liver; Malates; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1987 |
The mechanism of lead-induced mitochondrial Ca2+ efflux.
Topics: Animals; Biological Transport, Active; Calcium; Glutamates; Glutamic Acid; In Vitro Techniques; Kidney Cortex; Lead; Malates; Membrane Potentials; Mitochondria; NAD; Rabbits; Succinates; Succinic Acid; Sulfhydryl Compounds | 1987 |
Changes in pyridine nucleotide levels alter oxygen consumption and extra-mitochondrial phosphates in isolated mitochondria: a 31P-NMR and NAD(P)H fluorescence study.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fluorescent Dyes; Glutamates; Glutamic Acid; Magnetic Resonance Spectroscopy; Malates; Male; Mitochondria, Liver; NAD; NADP; Oxygen Consumption; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Rhodamines; Spectrometry, Fluorescence | 1987 |
Glutamate biosynthesis in Bacillus azotofixans. 15N NMR and enzymatic studies.
Topics: Ammonia; Bacillus; Glutamate Synthase; Glutamates; Glutamic Acid; Magnetic Resonance Spectroscopy; NAD; NADP; Nitrogen Fixation; Time Factors | 1988 |
Conversion of ammonia to glutamate by L-glutamic dehydrogenase, alcohol dehydrogenase and NAD+ immobilized within lipid-polyamide polyethyleneimine microcapsules.
Topics: Alcohol Dehydrogenase; Ammonia; Capsules; Enzymes, Immobilized; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Humans; In Vitro Techniques; Lipids; NAD; Polyethyleneimine; Toxins, Biological; Urea; Uremia | 1987 |
Cardiac mitochondrial abnormalities in a mouse model of the fetal alcohol syndrome.
Topics: Animals; Animals, Newborn; Electron Transport Complex IV; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetus; Gestational Age; Glutamates; Glutamic Acid; Malates; Mice; Mitochondria, Heart; NAD; Oxygen Consumption; Pregnancy; Succinate Dehydrogenase; Succinates; Succinic Acid | 1988 |
Enzymatic and structural modifications of mitochondrial NADH-ubiquinone reductase with autolysis as experimental model.
Topics: Animals; Coronary Disease; Electron Transport; Female; Ferricyanides; Glutamates; Glutamic Acid; Kinetics; Male; Mitochondria, Heart; NAD; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidative Phosphorylation; Oxygen Consumption; Peptides; Perissodactyla; Quinone Reductases; Ubiquinone; Vitamin K | 1988 |
Palmitoyl carnitine: an endogenous promotor of calcium efflux from rat heart mitochondria.
Topics: Animals; Calcium; Carnitine; Female; Glutamates; Glutamic Acid; Malates; Mitochondria, Heart; NAD; Oxidation-Reduction; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Succinates; Succinic Acid | 1988 |
Effect of styrene and other alkyl benzene derivatives on oxidation of FAD- and NAD-linked substrates in rat liver mitochondria.
Topics: Adenosine Triphosphatases; Animals; Flavin-Adenine Dinucleotide; Glutamates; Glutamic Acid; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Styrene; Styrenes; Succinates; Succinic Acid | 1988 |
Relationship between rate of gluconeogenesis and content of nicotinamide adenine dinucleotide in renal cortex.
Topics: Animals; Cytosol; Gluconeogenesis; Glutamates; Glutamic Acid; In Vitro Techniques; Ketoglutaric Acids; Kidney Cortex; Kinetics; Male; NAD; Picolinic Acids; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1981 |
[Interaction of n-alkanes with respiration and oxidative phosphorylation in rabbit heart mitochondria: n-hexane].
Topics: Animals; Glutamates; Glutamic Acid; Hexanes; Mitochondria, Heart; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Oxidative Phosphorylation; Oxygen Consumption; Rabbits; Succinate Dehydrogenase; Succinates; Succinic Acid; Temperature | 1981 |
[Interaction of n-alkanes with respiration and oxidative phosphorylation in rabbit heart mitochondria: n-nonane].
Topics: Alkanes; Animals; Glutamates; Glutamic Acid; Mitochondria, Heart; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Oxidative Phosphorylation; Oxygen Consumption; Rabbits; Succinate Dehydrogenase; Succinates; Succinic Acid; Temperature | 1981 |
[Interaction of n-alkanes with respiration and oxidative phosphorylation in rabbit heart mitochondria: n-dodecane, n-pentadecane and n-octadecane].
Topics: Alkanes; Animals; Glutamates; Glutamic Acid; Mitochondria, Heart; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Oxidative Phosphorylation; Oxygen Consumption; Rabbits; Succinate Dehydrogenase; Succinates; Succinic Acid; Temperature | 1981 |
Glutamate as a precursor of GABA in rat brain and peripheral tissues.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Carbon Dioxide; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Kidney; Liver; Male; NAD; Rats; Rats, Inbred Strains; Subcellular Fractions | 1981 |
A radioenzymatic ultramicro method applicable to the measurement of a wide range of metabolites.
Topics: Blood Glucose; Carbon Radioisotopes; Enzymes; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Humans; Ketoglutaric Acids; Lactates; Lactic Acid; Microchemistry; NAD; NADP; Radioisotopes | 1981 |
The mechanism, role and control of the inactivation of glutamate dehydrogenases in yeast.
Topics: Candida; Endopeptidases; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; NAD; NADP; Peptide Fragments; Phosphorylation; Protein Kinases; Saccharomyces cerevisiae | 1982 |
[Glutamate dehydrogenase from rat brain. Properties of the enzyme when acting in the direction of glutamate degradation].
Topics: Allosteric Regulation; Ammonia; Animals; Brain; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Kinetics; NAD; Rats; Rats, Inbred Strains | 1982 |
Ammonia formation from some amino acids by human term placental mitochondria.
Topics: Adenosine Diphosphate; Amino Acids; Ammonia; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Mitochondria; Models, Biological; NAD; Placenta; Pregnancy | 1982 |
Regulatory studies of L-glutamate dehydrogenase from Trypanosoma cruzi epimastigotes.
Topics: Animals; Glucose; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; NAD; NADP; Trypanosoma cruzi | 1983 |
Theoretical analysis of the glutamate dehydrogenase kinetics under physiological conditions.
Topics: Ammonia; Animals; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Kinetics; Mitochondria, Liver; Models, Biological; NAD; NADP | 1983 |
Effect of fatty acids and ketones on the activity of pyruvate dehydrogenase in skeletal-muscle mitochondria.
Topics: Acetoacetates; Animals; Calcium; Coenzyme A; Fatty Acids; Glutamates; Glutamic Acid; In Vitro Techniques; Ketoglutaric Acids; Ketones; Malates; Male; Mitochondria, Muscle; NAD; Oxygen Consumption; Palmitoylcarnitine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains | 1983 |
The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme.
Topics: Animals; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glutamic Acid; Glutamine; Kidney; Kinetics; Leukemia L1210; Liver Neoplasms, Experimental; Malate Dehydrogenase; Male; Mice; Mice, Inbred Strains; Mitochondria; Mitochondria, Liver; NAD; NADP; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thymoma; Thymus Neoplasms | 1984 |
Apparent identity of alpha-subunit of pyruvate dehydrogenase and the protein phosphorylated in the presence of glutamate in P2-fractions of rat cerebral cortex.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Mitochondria; Molecular Weight; NAD; Nerve Tissue Proteins; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Rats; Synaptosomes | 1984 |
NAD binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD.
Topics: Binding Sites; Diphtheria Toxin; Glutamates; Glutamic Acid; Macromolecular Substances; NAD; Peptide Fragments; Photochemistry | 1984 |
A kinetic study of the oxidative deamination of L-glutamate by Peptostreptococcus asaccharolyticus glutamate dehydrogenase using a variety of coenzymes.
Topics: Coenzymes; Deamination; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; NAD; Oxidation-Reduction; Peptostreptococcus | 1984 |
The kinetic mechanism of ox liver glutamate dehydrogenase in the presence of the allosteric effector ADP. The oxidative deamination of L-glutamate.
Topics: Adenosine Diphosphate; Animals; Cattle; Deamination; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Kinetics; Liver; NAD; Oxidation-Reduction | 1984 |
Hepatic mitochondrial respiration and transport of reducing equivalents in rats fed an energy dense diet.
Topics: Animals; Biological Transport; Diet, Reducing; Energy Intake; Energy Metabolism; Glutamic Acid; Glycerolphosphate Dehydrogenase; Malates; Male; Mitochondria, Liver; NAD; Obesity; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Rats; Rats, Wistar | 1995 |
Nicotinamide adenine dinucleotides mimic adenosine inhibition on synaptic transmission by decreasing glutamate release in rat hippocampal slices.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Amino Acids; Animals; Electrophysiology; Female; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; NAD; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Synaptic Transmission | 1993 |
Positive cooperativity with Hill coefficients of up to 6 in the glutamate concentration dependence of steady-state reaction rates measured with clostridial glutamate dehydrogenase and the mutant A163G at high pH.
Topics: Allosteric Regulation; Base Sequence; Cloning, Molecular; Clostridium; DNA Primers; Enzyme Stability; Escherichia coli; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Substrate Specificity; Succinates; Succinic Acid | 1995 |
Identification of Glu173 as the critical amino acid residue for the ADP-ribosyltransferase activity of Clostridium botulinum C3 exoenzyme.
Topics: 3T3 Cells; ADP Ribose Transferases; Animals; Base Sequence; Binding Sites; Botulinum Toxins; Glutamic Acid; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship; Tryptophan | 1995 |
[The drug "anfen" and the energy status of the liver].
Topics: Adenosine Triphosphate; Animals; Antioxidants; Electron Spin Resonance Spectroscopy; Energy Metabolism; Glutamic Acid; Kinetics; Malates; Male; Malonates; Mitochondria, Liver; NAD; Oxygen; Phospholipids; Rats; Rats, Wistar | 1995 |
The effect of ion pairs on the thermal stability of D-glyceraldehyde 3-phosphate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Base Sequence; Enzyme Stability; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Gram-Negative Anaerobic Bacteria; Hot Temperature; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Sequence Alignment | 1994 |
Purification and properties of lactate dehydrogenase from liver of Uromastix hardwickii.
Topics: Animals; Cations, Divalent; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Glutamic Acid; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Lizards; Molecular Weight; NAD; Oxalates; Oxalic Acid; Pyruvates; Pyruvic Acid | 1995 |
Involvement of glutamate 268 in the active site of human liver mitochondrial (class 2) aldehyde dehydrogenase as probed by site-directed mutagenesis.
Topics: Aldehyde Dehydrogenase; Binding Sites; Catalysis; DNA, Complementary; Glutamic Acid; Humans; Mitochondria, Liver; Models, Chemical; Mutagenesis, Site-Directed; NAD; Recombinant Proteins; Structure-Activity Relationship | 1995 |
Steady-state kinetics and transient studies of substrate and coenzyme analogue binding to clostridial glutamate dehydrogenase (GDH) during oxidative deamination.
Topics: Binding Sites; Clostridium; Coenzymes; Deamination; Glutamate Dehydrogenase; Glutamic Acid; Kinetics; NAD; Spectrometry, Fluorescence; Substrate Specificity | 1994 |
The changed pattern of substrate specificity in the K89L mutant of glutamate dehydrogenase of Clostridium symbiosum.
Topics: Amino Acids; Binding Sites; Cloning, Molecular; Clostridium; Escherichia coli; Glutamate Dehydrogenase; Glutamic Acid; Kinetics; Mutagenesis, Site-Directed; NAD; Substrate Specificity | 1994 |
Catalytic-rate improvement of a thermostable malate dehydrogenase by a subtle alteration in cofactor binding.
Topics: Aspartic Acid; Base Sequence; Catalysis; Enzyme Stability; Glutamic Acid; Hot Temperature; Malate Dehydrogenase; Models, Chemical; Molecular Sequence Data; Mutagenesis; Mutation; NAD; Oxaloacetates; Oxidation-Reduction; Protein Conformation; Recombinant Proteins; Solvents; Structure-Activity Relationship; Thermus; Viscosity | 1995 |
Influence of calcium on NADH and succinate oxidation by rat heart submitochondrial particles.
Topics: Adenosine Diphosphate; Animals; Calcium; Electron Transport; Glutamic Acid; Male; Mitochondria, Heart; NAD; Oxygen Consumption; Rats; Rats, Wistar; Submitochondrial Particles; Succinates; Succinic Acid | 1995 |
In the thermophilic archaeon Sulfolobus solfataricus a DNA-binding protein is in vitro (Adpribosyl)ated.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Amino Acids; Animals; Cattle; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; DNA-Binding Proteins; DNA, Bacterial; Glutamic Acid; Histones; Hot Temperature; Lysine; Molecular Sequence Data; Molecular Weight; NAD; Nucleic Acid Denaturation; Peptide Fragments; Sulfolobus | 1995 |
The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant.
Topics: Amino Acid Sequence; Base Sequence; Gene Deletion; Gene Expression; Glucose; Glucose-6-Phosphate Isomerase; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Models, Genetic; Molecular Sequence Data; Mutation; NAD; NADP; Plasmids; Restriction Mapping; Saccharomyces cerevisiae; Suppression, Genetic; Transformation, Genetic | 1993 |
Proline transport in rat kidney mitochondria.
Topics: Amino Acid Transport Systems, Neutral; Animals; Biological Transport; Carbon Radioisotopes; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carrier Proteins; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kidney; Kinetics; Male; Mersalyl; Mitochondria; NAD; Proline; Rats; Rats, Wistar; Temperature | 1994 |
Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; Animals; Asian People; Base Sequence; Binding Sites; Catalysis; DNA Primers; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Mitochondria, Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligodeoxyribonucleotides; Rats; Recombinant Proteins; Sequence Homology, Amino Acid | 1994 |
Calcium and 2-oxoglutarate-mediated control of aspartate formation by rat heart mitochondria.
Topics: Animals; Aspartic Acid; Calcium; Dinitrophenols; Enzyme Activation; Glutamates; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Malates; Membrane Potentials; Mitochondria, Heart; Models, Biological; NAD; Pyruvates; Pyruvic Acid; Rats | 1994 |
Bilateral seizure-related changes of extracellular glutamate concentration in hippocampi during development of amygdaloid kindling.
Topics: Amygdala; Animals; Electrodes, Implanted; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Kindling, Neurologic; Male; Microdialysis; NAD; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1994 |
Activation of bovine liver glutamate dehydrogenase by covalent reaction of adenosine 5'-O-[S-(4-bromo-2,3-dioxobutyl)thiophosphate] with arginine-459 at an ADP regulatory site.
Topics: Adenosine Diphosphate; Affinity Labels; Allosteric Regulation; Amino Acid Sequence; Animals; Cattle; Enzyme Activation; Glutamate Dehydrogenase; Glutamic Acid; Kinetics; Ligands; Liver; Molecular Sequence Data; NAD; Peptide Fragments; Sequence Analysis; Thionucleotides | 1994 |
Cerebral mitochondrial redox states during metabolic stress in the immature rat.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Animals, Newborn; Brain; Brain Diseases; Brain Ischemia; Glutamic Acid; Hydroxybutyrates; Hypoglycemia; Hypoxia; Ketoglutaric Acids; Mitochondria; NAD; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Stress, Physiological | 1994 |
A flow-injection biosensor system for the amperometric determination of creatinine: simultaneous compensation of endogenous interferents.
Topics: Amino Acid Oxidoreductases; Aminohydrolases; Ammonia; Biosensing Techniques; Buffers; Creatinine; Enzymes, Immobilized; Evaluation Studies as Topic; Flow Injection Analysis; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Kinetics; NAD; Sensitivity and Specificity | 1993 |
Glycerol 3-phosphate and lactate as indicators of the cerebral cytoplasmic redox state in severe and mild hypoxia respectively: a 13C- and 31P-n.m.r. study.
Topics: Acetates; Adenosine Triphosphate; Alanine; Cerebral Cortex; Cytoplasm; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycerophosphates; Hypoxia, Brain; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Oxidation-Reduction; Phosphocreatine | 1993 |
The mechanism of substrate and coenzyme binding to clostridial glutamate dehydrogenase during oxidative deamination.
Topics: Binding Sites; Clostridium; Deamination; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Kinetics; NAD; Oxidation-Reduction | 1993 |
Function and expression of yeast mitochondrial NAD- and NADP-specific isocitrate dehydrogenases.
Topics: Blotting, Southern; Cloning, Molecular; Cytosol; DNA, Fungal; DNA, Recombinant; Electron Transport Complex IV; Genes, Fungal; Glutamates; Glutamic Acid; Isocitrate Dehydrogenase; Isoenzymes; Kinetics; Mitochondria; NAD; NADP; Oxygen Consumption; Restriction Mapping; Saccharomyces cerevisiae | 1993 |
Energy-transducing nicotinamide nucleotide transhydrogenase. Nucleotide binding properties of the purified enzyme and proteolytic fragments.
Topics: Amino Acid Sequence; Aniline Compounds; Animals; Binding Sites; Carbon Radioisotopes; Cattle; Dicyclohexylcarbodiimide; Glutamates; Glutamic Acid; Kinetics; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; NAD; NADP; NADP Transhydrogenases; Oxidation-Reduction; Peptide Fragments; Quinolines | 1993 |
Extraction and assay of protein from single plant cells.
Topics: Glutamic Acid; Hydrolysis; Indicators and Reagents; NAD; Plant Cells; Plant Proteins; Plants | 1995 |
Analysis of the catalytic site of the actin ADP-ribosylating Clostridium perfringens iota toxin.
Topics: Actins; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Affinity Labels; Amino Acid Sequence; Bacterial Toxins; Binding Sites; Catalysis; Clostridium perfringens; Cyanogen Bromide; Glutamic Acid; Molecular Sequence Data; NAD; Peptide Fragments; Photochemistry; Ultraviolet Rays | 1996 |
Unusually stable NAD-specific glutamate dehydrogenase from the alkaliphile Amphibacillus xylanus.
Topics: Acetonitriles; Alcohols; Ammonia; Bacillus; Bacterial Proteins; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; NAD; Temperature | 1996 |
Visualization of glutamate release from rat spinal cord with a confocal laser scanning microscope.
Topics: Animals; Capsaicin; Glutamate Dehydrogenase; Glutamic Acid; In Vitro Techniques; Male; Microscopy, Confocal; NAD; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Spinal Cord; Tetrodotoxin | 1996 |
Oxygen activation by cytochrome P450BM-3: effects of mutating an active site acidic residue.
Topics: Bacterial Proteins; Binding Sites; Cytochrome P-450 Enzyme System; Enzyme Activation; Glutamic Acid; Glutamine; Hydroxylation; Laurates; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Myristates; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxygen Consumption; Palmitates; Protein Structure, Secondary; Substrate Specificity | 1997 |
Ammonium and glutamate released by neurons are signals regulating the nutritive function of a glial cell.
Topics: Animals; Bees; Cell Communication; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Mitochondria; Models, Neurological; NAD; NADP; Neuroglia; Neurons; Photoreceptor Cells, Invertebrate; Quaternary Ammonium Compounds; Retina; Signal Transduction | 1997 |
GTP-binding proteins coupling to glutamate receptors on bovine retinal membranes.
Topics: Animals; Cattle; Cell Membrane; Cholera Toxin; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); NAD; Receptors, Glutamate; Retina; Rod Cell Outer Segment; Virulence Factors, Bordetella | 1993 |
Activation of Ca2+-dependent currents in dorsal root ganglion neurons by metabotropic glutamate receptors and cyclic ADP-ribose precursors.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cells, Cultured; Cyclic ADP-Ribose; Cyclic GMP; Ganglia, Spinal; Glutamic Acid; Membrane Potentials; Muscle Proteins; NAD; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Ryanodine Receptor Calcium Release Channel; Synaptic Transmission | 1997 |
Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion.
Topics: Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Binding Sites; Cattle; Crystallography, X-Ray; Enzyme Stability; Glutamic Acid; Mitochondria; Models, Molecular; Molecular Sequence Data; NAD; Protein Conformation | 1997 |
Kinetic studies on the binding of 1,N6-etheno-NAD+ to glutamate dehydrogenase from Clostridium symbiosum.
Topics: Clostridium; Glutamate Dehydrogenase; Glutamic Acid; Isomerism; Kinetics; Mathematics; NAD; Spectrometry, Fluorescence | 1997 |
Critical glutamic acid residues affecting the mechanism and nucleotide specificity of Vibrio harveyi aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; Autoradiography; Chromatography, Thin Layer; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Nucleotides; Structure-Activity Relationship; Vibrio | 1997 |
Increased red cell glutamine availability in sickle cell anemia: demonstration of increased active transport, affinity, and increased glutamate level in intact red cells.
Topics: Anemia, Sickle Cell; Biological Transport, Active; Erythrocytes; Glutamic Acid; Glutamine; Humans; Kinetics; NAD | 1997 |
In situ measurement of glutamate concentrations in the periportal, intermediate, and pericentral zones of rat liver.
Topics: Age Factors; Animals; Animals, Newborn; Fasting; Formazans; Glutamate Dehydrogenase; Glutamic Acid; Histocytochemistry; Hot Temperature; Hydrogen-Ion Concentration; Immunohistochemistry; Liver; Male; NAD; Rats; Rats, Wistar; Time Factors | 1997 |
The nutritive function of glia is regulated by signals released by neurons.
Topics: Alanine; Ammonia; Animals; Bees; Glucose; Glutamic Acid; In Vitro Techniques; Male; Models, Biological; NAD; NADP; Neuroglia; Neurons; Photoreceptor Cells, Invertebrate; Proline; Retina; Signal Transduction | 1997 |
Crystallization and characterization of bovine liver glutamate dehydrogenase.
Topics: Animals; Cattle; Crystallization; Crystallography, X-Ray; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Liver; Models, Structural; NAD; Polyethylene Glycols; Protein Binding; Protein Conformation; Rotation | 1997 |
Intersubunit communication in hybrid hexamers of K89L/A163G/S380A and C320S mutants of glutamate dehydrogenase from Clostridium symbiosum.
Topics: Alanine; Allosteric Regulation; Clostridium; Dithionitrobenzoic Acid; Glutamate Dehydrogenase; Glutamic Acid; Lysine; NAD; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Proteins; Serine | 1997 |
Involvement of Glu-264 and Arg-235 in the essential interaction between the catalytic imidazole and substrate for the D-lactate dehydrogenase catalysis.
Topics: Arginine; Catalysis; Diethyl Pyrocarbonate; Enzyme Inhibitors; Glutamic Acid; Hydrogen-Ion Concentration; Imidazoles; L-Lactate Dehydrogenase; Mutagenesis, Site-Directed; NAD; Oxamic Acid; Substrate Specificity | 1997 |
A method for the isolation of tegument syncytium mitochondria from Taenia crassiceps cysticerci and partial characterization of their aerobic metabolism.
Topics: Animals; Cell Fractionation; Cell Membrane; Cysticercus; Female; Glutamic Acid; Malates; Membrane Potentials; Mice; Microscopy, Electron; Mitochondria; NAD; Oxidative Phosphorylation; Oxygen Consumption; Saponins; Solubility; Succinate Dehydrogenase; Succinates | 1998 |
Carbon-flux distribution in the central metabolic pathways of Corynebacterium glutamicum during growth on fructose.
Topics: Biological Transport; Carbon Radioisotopes; Corynebacterium; Fructose; Glucose; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Magnetic Resonance Spectroscopy; NAD; NADP; Pentose Phosphate Pathway; Phosphoenolpyruvate Sugar Phosphotransferase System | 1998 |
Roles of negatively charged surface residues of putidaredoxin in interactions with redox partners in p450cam monooxygenase system.
Topics: Aspartic Acid; Binding Sites; Camphor 5-Monooxygenase; Electricity; Electron Transport; Ferredoxins; Glutamic Acid; Models, Molecular; Mutagenesis, Site-Directed; NAD; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Potentiometry; Protein Binding; Protein Structure, Secondary; Spectrophotometry | 1998 |
Imaging of endogenous neurotransmitter release.
Topics: Animals; Diagnostic Imaging; Fluorescence; gamma-Aminobutyric Acid; Glutamic Acid; NAD; NADP; Neurotransmitter Agents; Retina; Ultraviolet Rays; Zebrafish | 1998 |
Correction for inner filter effects in turbid samples: fluorescence assays of mitochondrial NADH.
Topics: Adenosine Diphosphate; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Fluorescent Dyes; Glutamic Acid; Least-Squares Analysis; Light; Milk; Mitochondria, Heart; NAD; Nephelometry and Turbidimetry; Scattering, Radiation; Spectrometry, Fluorescence; Swine | 1998 |
N-tosyl-L-phenylalanine chloromethyl ketone, a serine protease inhibitor, identifies glutamate 398 at the coenzyme-binding site of human aldehyde dehydrogenase. Evidence for a second "naked anion" at the active site.
Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; Binding Sites; Chymotrypsin; Cytoplasm; Glutamic Acid; Humans; Isoenzymes; Kinetics; Mitochondria; Molecular Sequence Data; NAD; Peptide Fragments; Peptide Mapping; Serine Proteinase Inhibitors; Substrate Specificity; Tosylphenylalanyl Chloromethyl Ketone; Trypsin | 1998 |
Decreasing the stability and changing the substrate specificity of the Bacillus stearothermophilus alcohol dehydrogenase by single amino acid replacements.
Topics: Alcohol Dehydrogenase; Alcohols; Amino Acid Substitution; Binding Sites; Catalytic Domain; Enzyme Stability; Escherichia coli; Geobacillus stearothermophilus; Glutamic Acid; Guanidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; NAD; Proline; Protein Denaturation; Recombinant Proteins; Substrate Specificity; Temperature | 1998 |
Site-directed mutagenesis of human dihydrolipoamide dehydrogenase: role of lysine-54 and glutamate-192 in stabilizing the thiolate-FAD intermediate.
Topics: Base Sequence; Circular Dichroism; Dihydrolipoamide Dehydrogenase; DNA Primers; Electron Transport; Enzyme Stability; Escherichia coli; Flavin-Adenine Dinucleotide; Genetic Vectors; Glutamic Acid; Humans; In Vitro Techniques; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NAD; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence | 1999 |
Energy metabolism and NAD-NADH redox state in brain slices in response to glutamate exposure and ischemia.
Topics: Animals; Brain; Brain Ischemia; Energy Metabolism; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Lactic Acid; NAD; Oxidation-Reduction; Phosphates; Phosphorylation; Rats; Rats, Sprague-Dawley | 1999 |
A structural explanation for the retinal specificity of class 1 ALDH enzymes.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitochondrial; Animals; Binding Sites; Cattle; Crystallography, X-Ray; Glutamic Acid; Isoenzymes; NAD; Protein Conformation; Retinal Dehydrogenase; Retinaldehyde; Sheep; Structure-Activity Relationship; Substrate Specificity | 1999 |
Evaluation of the roles of the conserved residues of aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amino Acid Sequence; Arginine; Binding Sites; Conserved Sequence; Glutamic Acid; Humans; Kinetics; Mutagenesis; NAD; Recombinant Fusion Proteins; Serine; Threonine | 1999 |
Glutamate neurotoxicity in rat cerebellar granule cells involves cytochrome c release from mitochondria and mitochondrial shuttle impairment.
Topics: Animals; Cells, Cultured; Cerebellum; Cytochrome c Group; Dihydroxyacetone Phosphate; Electron Transport Complex II; Electron Transport Complex III; Glutamic Acid; Glycerophosphates; Malates; Mitochondria; Multienzyme Complexes; NAD; NAD(P)H Dehydrogenase (Quinone); Oxaloacetic Acid; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Rats; Succinate Dehydrogenase | 1999 |
Increase in external glutamate and NMDA receptor activation contribute to H2O2-induced neuronal apoptosis.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Extracellular Space; Glutamic Acid; Hydrogen Peroxide; Hydroxyl Radical; Mice; NAD; Neurons; Oxidants; Poly(ADP-ribose) Polymerases; Receptors, N-Methyl-D-Aspartate | 1999 |
Differences in the roles of conserved glutamic acid residues in the active site of human class 3 and class 2 aldehyde dehydrogenases.
Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; Animals; Binding Sites; Conserved Sequence; Glutamic Acid; Humans; Isoenzymes; Kinetics; Models, Molecular; Mutagenesis; NAD; Protein Binding; Rats; Recombinant Proteins | 1999 |
Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission.
Topics: Animals; Autoradiography; Brain; Cells, Cultured; DNA Damage; Enzyme Activation; Glutamic Acid; Immunohistochemistry; Kidney; Mice; Mice, Knockout; N-Methylaspartate; NAD; Nitric Oxide; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Proteins; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2000 |
Imaging extracellular waves of glutamate during calcium signaling in cultured astrocytes.
Topics: Animals; Astrocytes; Biological Transport; Calcium; Calcium Signaling; Calibration; Cells, Cultured; Extracellular Space; Glutamate Dehydrogenase; Glutamic Acid; Image Processing, Computer-Assisted; Microscopy, Fluorescence; NAD; Physical Stimulation; Rats; Rats, Sprague-Dawley | 2000 |
Metabolic analysis of glutamate production by Corynebacterium glutamicum.
Topics: Biomedical Engineering; Bioreactors; Biotechnology; Corynebacterium; Fermentation; Glutamic Acid; Glycolysis; Kinetics; NAD | 1999 |
Studies of aminochrome toxicity in a mouse derived neuronal cell line: is this toxicity mediated via glutamate transmission?
Topics: Animals; Catalase; Cell Line; Cell Survival; Cerebral Cortex; Dicumarol; Dopamine; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Glutamic Acid; Indolequinones; Indoles; Mice; Models, Biological; NAD; NAD(P)H Dehydrogenase (Quinone); Neurons; Oxidation-Reduction; Quinoxalines; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Uncoupling Agents | 2000 |
Basis for half-of-the-site reactivity and the dominance of the K487 oriental subunit over the E487 subunit in heterotetrameric human liver mitochondrial aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Amino Acid Substitution; Asian People; Binding Sites; Dimerization; Enzyme Activation; Glutamic Acid; Humans; Kinetics; Lysine; Mitochondria, Liver; Mutagenesis, Site-Directed; NAD; Peptide Fragments | 2000 |
Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress.
Topics: Aconitate Hydratase; Animals; Carmustine; Cerebral Cortex; Citrate (si)-Synthase; Citric Acid Cycle; Dose-Response Relationship, Drug; Electron Transport; Enzyme Activation; Glucose; Glutamic Acid; Glutathione Reductase; Guinea Pigs; Hydrogen Peroxide; Ketoglutarate Dehydrogenase Complex; Malate Dehydrogenase; NAD; NADP; Oxidative Stress; Pyrimidines; Rotenone; Spectrometry, Fluorescence; Succinate Dehydrogenase; Synaptosomes | 2000 |
The gdhB gene of Pseudomonas aeruginosa encodes an arginine-inducible NAD(+)-dependent glutamate dehydrogenase which is subject to allosteric regulation.
Topics: Allosteric Regulation; Amino Acid Sequence; Arginine; Base Sequence; Citric Acid; Cloning, Molecular; Enzyme Induction; Gene Expression Regulation, Bacterial; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutation; NAD; Promoter Regions, Genetic; Protein Conformation; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid | 2001 |
Chain length analysis of ADP-ribose polymers generated by poly(ADP-ribose) polymerase (PARP) as a function of beta-NAD+ and enzyme concentrations.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Hydrolysis; NAD; Poly(ADP-ribose) Polymerases; Polymers; Thymus Gland | 2000 |
Construction, separation and properties of hybrid hexamers of glutamate dehydrogenase in which five of the six subunits are contributed by the catalytically inert D165S.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Substitution; Catalysis; Chromatography, Affinity; Clostridium; Coloring Agents; Cysteine; Dithionitrobenzoic Acid; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Ligands; Mutation; NAD; Protein Denaturation; Protein Folding; Protein Renaturation; Protein Structure, Quaternary; Protein Subunits; Recombinant Fusion Proteins; Triazines; Ultrafiltration; Urea | 2001 |
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Animals; Catalytic Domain; Cattle; Crystallography; Gene Expression Regulation, Enzymologic; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Ketoglutaric Acids; Ligands; Models, Molecular; NAD; NADP; Purines; Species Specificity | 2001 |
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.
Topics: Adrenergic alpha-Antagonists; Ammonia; Animals; Antioxidants; Cell Fractionation; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Glucose; Glutamic Acid; Imidazoles; Imidazolidines; Ketoglutaric Acids; Lactic Acid; Male; Mitochondria; NAD; Oxidation-Reduction; Piperazines; Prazosin; Pyrimidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Sorbitol; Thioctic Acid | 2001 |
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Apoptosis; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Cyclosporine; Electron Transport; Electron Transport Complex I; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Membrane Potentials; Mitochondria; Models, Biological; NAD; NADH, NADPH Oxidoreductases; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligomycins; omega-N-Methylarginine; Permeability; Rats; Rats, Wistar; Receptors, Glutamate; Rotenone; Single-Blind Method; Succinate Cytochrome c Oxidoreductase | 2001 |
Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Enzyme Activation; Escherichia coli; Folic Acid; Glutamic Acid; Glutamine; Kinetics; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Spectrophotometry; Vitamin K | 2001 |
Glutamate synthesis via photoreduction of NADP+ by photostable chlorophyllide coupled with polyethylene-glycol.
Topics: Carboxylic Ester Hydrolases; Chlorophyllides; Drug Stability; Ferredoxin-NADP Reductase; Glutamate Dehydrogenase; Glutamic Acid; Indicators and Reagents; Ketoglutaric Acids; Kinetics; Light; Magnoliopsida; Mercaptoethanol; NAD; NADP; Oxidation-Reduction; Polyethylene Glycols; Saccharomyces cerevisiae | 2001 |
Evidence of a role for cyclic ADP-ribose in calcium signalling and neurotransmitter release in cultured astrocytes.
Topics: Adenosine Diphosphate Ribose; Administration, Topical; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation; Astrocytes; Calcium Signaling; Cell Communication; Cells, Cultured; Coculture Techniques; Connexin 43; Cyclic ADP-Ribose; gamma-Aminobutyric Acid; Glutamic Acid; Glycyrrhetinic Acid; Hippocampus; Immunoblotting; Membrane Glycoproteins; Microscopy, Fluorescence; Models, Neurological; NAD; NAD+ Nucleosidase; Neurons; Neurotransmitter Agents; Rats; Spectrometry, Fluorescence | 2001 |
DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria.
Topics: Animals; Brain; Glutamic Acid; Malates; Membrane Potentials; Mitochondria; NAD; Oxygen Consumption; Rats; Reactive Oxygen Species; Succinic Acid | 2001 |
Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinose.
Topics: Amino Sugars; Carbohydrate Sequence; Cell Membrane; Cell-Free System; Cytoplasm; Drug Resistance; Escherichia coli; Glutamic Acid; Lipid A; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Mutation; NAD; Oxygen; Polymyxins; Protein Binding; Protein Structure, Tertiary; Time Factors; Uridine Diphosphate Glucose; Uridine Diphosphate Glucuronic Acid | 2002 |
Glutamate-loading stimulates metabolic flux and improves cell recovery following chemical hypoxia in isolated cardiomyocytes.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Glutamic Acid; Heart Ventricles; Male; NAD; Rats; Rats, Wistar; Reperfusion | 2001 |
The crystal structure and stereospecificity of levodione reductase from Corynebacterium aquaticum M-13.
Topics: Binding Sites; Catalysis; Circular Dichroism; Corynebacterium; Crystallization; Crystallography; Enzyme Inhibitors; Escherichia coli; Gene Expression; Glutamic Acid; Glycols; Hydrogen Bonding; Models, Molecular; Molecular Structure; Mutation; NAD; Oxidoreductases; Protein Structure, Secondary; Recombinant Proteins; Static Electricity; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2003 |
Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress.
Topics: Animals; Apoptosis; Blotting, Western; Cell Death; Cell Nucleus; Coumarins; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Glutamic Acid; Immunohistochemistry; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; NAD; Neurons; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
NAD(P)H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices.
Topics: Animals; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Flavin-Adenine Dinucleotide; Fluorescence; Fluorescent Dyes; Glutamic Acid; Hippocampus; In Vitro Techniques; Iontophoresis; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria; NAD; NADP; Neurons; Optics and Photonics; Stimulation, Chemical; Synapses; Synaptic Transmission | 2003 |
The reported human NADsyn2 is ammonia-dependent NAD synthetase from a pseudomonad.
Topics: Amide Synthases; Ammonia; Base Sequence; Chromosomes, Human, Pair 22; Cloning, Molecular; CpG Islands; Cysteine; DNA; Gene Library; Glutamic Acid; Glutamine; Humans; Hydrolysis; Molecular Sequence Data; Muscles; NAD; Nicotinamidase; Open Reading Frames; Operon; Phylogeny; Protein Structure, Tertiary; Pseudomonas; Sequence Homology, Nucleic Acid | 2003 |
Occurrence of two different glutamate dehydrogenase activities in the halophilic bacterium Salinibacter ruber.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Bacterial Proteins; Bacteroidetes; Enzyme Activation; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ketoglutaric Acids; Leucine; NAD; NADP; Phenylalanine; Potassium Chloride; Sodium Chloride; Substrate Specificity | 2003 |
[Determination of L-lactate, L-malate, L-glutamate and ethyl alcohol in the enzyme-optic test by means of the DPN analog, 3-acetylpyridine-DPN].
Topics: Ethanol; Glutamates; Glutamic Acid; L-Lactate Dehydrogenase; Lactates; Malate Dehydrogenase; Malates; NAD; Oxidoreductases; Pyridines | 1962 |
EFFECT OF CATIONS ON THE ACTIVITY OF L-GLUTAMIC ACID DEHYDROGENASE.
Topics: Amino Acid Oxidoreductases; Animals; Arginine Vasopressin; Cations; Crustacea; Glutamates; Glutamic Acid; Magnesium; Muscles; NAD; Ouabain; Potassium; Research; Sodium; Strophanthins; Tubocurarine; Vasopressins | 1963 |
PREPARATIVE ENZYMATIC-SYNTHESIS OF THE THREO AND ERYTHRO ISOMERS OF GAMMA-HYDROXY-L-GLUTAMIC ACID.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Gamma Rays; Glutamates; Glutamic Acid; Glutaminase; Glutarates; Indicators and Reagents; Isomerism; NAD; Research | 1963 |
SYNTHESIS OF GLUTAMATE FROM ALPHA-OXOGLUTARATE AND AMMONIA IN RAT-LIVER MITOCHONDRIA. I. COMPARISON OF DIFFERENT HYDROGEN DONORS.
Topics: Amino Acids; Ammonia; Amobarbital; Anti-Bacterial Agents; Aspartate Aminotransferases; Dinitrophenols; Glutamates; Glutamic Acid; Hydrogen; Isocitrate Dehydrogenase; Ketoglutaric Acids; Liver; Malonates; Metabolism; Mitochondria; Mitochondria, Liver; NAD; NADP; Oligomycins; Pharmacology; Rats; Research; Succinates | 1963 |
SYNTHESIS OF GLUTAMATE FROM ALPHA-OXOGLUTARATE AND AMMONIA IN RAT-LIVER MITOCHONDRIA. II. SUCCINATE AS HYDROGEN DONOR.
Topics: Adenosine Triphosphate; Ammonia; Anti-Bacterial Agents; Carbohydrate Metabolism; Dinitrophenols; Enzyme Inhibitors; Glutamates; Glutamic Acid; Hydrogen; Ketoglutaric Acids; Liver; Metabolism; Mitochondria; Mitochondria, Liver; NAD; Oligomycins; Pharmacology; Rats; Research; Succinates; Succinic Acid | 1963 |
SYNTHESIS OF GLUTAMATE FROM ALPHA-OXOGLUTARATE AND AMMONIA IN RAT-LIVER MITOCHONDRIA. III. MALATE AS HYDROGEN DONOR.
Topics: Adenosine Triphosphate; Ammonia; Amobarbital; Anti-Bacterial Agents; Aspartic Acid; Dinitrophenols; Enzyme Inhibitors; Glutamates; Glutamic Acid; Hydrogen; Ketoglutaric Acids; Liver; Malates; Mitochondria; Mitochondria, Liver; NAD; Oligomycins; Pharmacology; Rats; Research | 1963 |
SYNTHESIS OF GLUTAMATE FROM ALPHA-OXOGLUTARATE AND AMMONIA IN RAT-LIVER MITOCHONDRIA. IV. REDUCTION OF NICOTINAMIDE NUCLEOTIDE COUPLED WITH THE AEROBIC OXIDATION OF TETRAMETHYL-RHO-PHENYLENEDIAMINE.
Topics: Ammonia; Amobarbital; Aniline Compounds; Anti-Bacterial Agents; Dinitrophenols; Enzyme Inhibitors; Glutamates; Glutamic Acid; Ketoglutaric Acids; Liver; Malates; Metabolism; Mitochondria; Mitochondria, Liver; Myocardium; NAD; Niacinamide; Nucleotides; Oligomycins; Oxidation-Reduction; Pharmacology; Phenylenediamines; Rabbits; Rats; Research; Succinates | 1963 |
SYNTHESIS OF GLUTAMATE FROM ALPHA-OXOGLUTARATE AND AMMONIA IN RAT-LIVER MITOCHONDRIA. V. ENERGETICS AND MECHANISM.
Topics: Adenosine Triphosphate; Ammonia; Anti-Bacterial Agents; Carbohydrate Metabolism; Fumarates; Glutamates; Glutamic Acid; Ketoglutaric Acids; Liver; Malates; Metabolism; Mitochondria; Mitochondria, Liver; NAD; Oligomycins; Pharmacology; Rats; Research; Succinates | 1963 |
FORMATION OF AMMONIA FROM GLUTAMATE BY MITOCHONDRIA.
Topics: Ammonia; Fumarates; Glutamates; Glutamic Acid; Keto Acids; Kidney; Liver; Malonates; Metabolism; Mitochondria; NAD; Pharmacology; Proteins; Research | 1964 |
STUDIES ON SPECIFIC ENZYME INHIBITORS. 8. ENZYME-REGULATORY MECHANISM OF THE ENTRY OF GLUTAMIC ACID INTO METABOLIC PATHWAYS IN KIDNEY TISSUE.
Topics: Acetates; Adenosine Triphosphate; Alanine Transaminase; Aspartate Aminotransferases; Enzyme Inhibitors; Glutamates; Glutamic Acid; Glutamine; Glutarates; Hexokinase; Kidney; Malates; Metabolic Networks and Pathways; Metabolism; Mitochondria; NAD; Oxalates; Pyruvates; Rats; Research | 1964 |
AMINO GROUP FORMATION AND GLUTAMATE SYNTHESIS IN STREPTOCOCCUS BOVIS.
Topics: Amino Acids; Asparagine; Aspartic Acid; Carbon; Caseins; Culture Media; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Isocitrate Dehydrogenase; Metabolism; NAD; NADP; Nitrogen; Nucleotides; Research; Streptococcus; Streptococcus bovis | 1964 |
[ROLE OF GLUTAMIC DEHYDROGENASE AND ASPARTIC/GLUTAMIC TRANSAMINASE IN THE OXIDATION OF GLUTAMATE BY SARCOSOMES FROM PIG HEART AND UTERUS].
Topics: Amino Acids; Animals; Antimetabolites; Arsenicals; Aspartate Aminotransferases; Aspartic Acid; Chromatography; Cytoplasmic Granules; Female; Formates; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Humans; Malonates; Manometry; Metabolism; Mitochondria, Muscle; Muscle, Smooth; Myocardium; NAD; Pharmacology; Research; Swine; Uterus | 1964 |
METABOLIC ACTIVITY IN COXIELLA BURNETII.
Topics: Acetates; Amino Acids; Carbohydrate Metabolism; Citric Acid Cycle; Coxiella; Coxiella burnetii; Fumarates; Glutamates; Glutamic Acid; Keto Acids; Ketoglutaric Acids; Malates; NAD; Oxaloacetates; Pyruvates; Research; Serine; Succinates | 1964 |
COENZYME BINDING BY X-IRRADIATED GLUTAMATE AND LACTATE DEHYDROGENASE.
Topics: Fluorometry; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; L-Lactate Dehydrogenase; NAD; Radiation Effects; Research; Ultracentrifugation | 1965 |
CONTROL OF GLUTAMATE OXIDATION IN BRAIN AND LIVER MITOCHONDRIAL SYSTEMS.
Topics: Adenine Nucleotides; Amino Acids; Aspartate Aminotransferases; Brain; Brain Chemistry; Citric Acid Cycle; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Liver; Malates; Malonates; Mitochondria; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Pharmacology; Rats; Research | 1965 |
THE OXIDATION OF GLUTAMATE BY RAT-LIVER MITOCHONDRIA.
Topics: Amino Acids; Arsenicals; Chromatography; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Liver; Malates; Malonates; Mitochondria; Mitochondria, Liver; NAD; Oxaloacetates; Oxidation-Reduction; Pharmacology; Pyruvates; Rats; Research; Succinates; Sulfinic Acids | 1965 |
Glutamate synthesis and the control of reactions linked with the nicotinamide-adenine dinucleotide coenzymes in mitochondria.
Topics: Coenzymes; Glutamates; Glutamic Acid; Mitochondria; NAD | 1962 |
Glutamate-induced differential mitochondrial response in young and adult rats.
Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Calcium Signaling; Cell Survival; Cerebral Cortex; Fluorescent Dyes; Fura-2; Glutamic Acid; Intracellular Membranes; L-Lactate Dehydrogenase; Microscopy, Fluorescence; Mitochondria; NAD; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2004 |
Limited transfer of cytosolic NADH into mitochondria at high cardiac workload.
Topics: Acetates; Animals; Carbon Isotopes; Coronary Circulation; Cytosol; Dogs; Energy Metabolism; Female; Glutamic Acid; Heart; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Myocardial Contraction; Myocardium; NAD; Oxygen; Succinic Acid | 2004 |
A two-dimensional imaging biosensor to monitor enhanced brain glutamate release stimulated by nicotine.
Topics: Animals; Animals, Newborn; Biosensing Techniques; Brain; Calcium Chloride; Diagnostic Imaging; Dose-Response Relationship, Drug; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mice; Monitoring, Physiologic; NAD; Nicotine; Nicotinic Agonists; Potassium Chloride | 2004 |
Inhibition of chlorophyll biosynthesis by mercury in excised etiolated maize leaf segments during greening: effect of 2-oxoglutarate.
Topics: Aminolevulinic Acid; Ammonia; Chlorophyll; Dose-Response Relationship, Drug; Glutamate Synthase; Glutamic Acid; Ketoglutaric Acids; Light; Mercury; NAD; Photosynthesis; Plant Leaves; Porphobilinogen Synthase; Radiation-Protective Agents; Zea mays | 2004 |
Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients.
Topics: Adenosine Diphosphate; Adult; Aged; Amobarbital; Antioxidants; Cells, Cultured; Coenzymes; Drug Interactions; Female; Fibroblasts; Glutamic Acid; Humans; Male; Middle Aged; Mitochondria; NAD; Oxygen; Parkinson Disease; Pyruvic Acid; Skin; Ubiquinone | 2004 |
Involvement of a Glu71-Arg64 couple in the access channel for NADH in cytochrome p450nor.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Cytochrome P-450 Enzyme System; Fusarium; Glutamic Acid; Heme; Molecular Structure; NAD; Oxidoreductases; Point Mutation | 2004 |
The role of active site glutamate residues in catalysis of Rhodobacter capsulatus xanthine dehydrogenase.
Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Dithionite; Dose-Response Relationship, Drug; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Mutation; NAD; Oxygen; Protein Binding; Protein Structure, Tertiary; Rhodobacter capsulatus; Spectrophotometry; Substrate Specificity; Sulfur; Time Factors; Ultraviolet Rays; Uric Acid; Xanthine; Xanthine Dehydrogenase | 2004 |
A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenase.
Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Brain; Cell Line; Cyclic N-Oxides; Dose-Response Relationship, Drug; Glutamate Dehydrogenase; Glutamic Acid; Humans; Kinetics; Malates; Membrane Potentials; Microscopy, Confocal; Mitochondria; NAD; Neurons; Oxygen; PC12 Cells; Phenotype; Rats; Reactive Oxygen Species; Spin Labels; Succinic Acid; Sulfites; Time Factors | 2004 |
The ND1 gene of complex I is a mutational hot spot for Leber's hereditary optic neuropathy.
Topics: Adult; Aged; DNA Mutational Analysis; DNA, Mitochondrial; Family Health; Female; Ferricyanides; Glutamic Acid; Haplotypes; Humans; Inhibitory Concentration 50; Lysine; Magnetic Resonance Spectroscopy; Male; Microscopy, Electron, Transmission; Middle Aged; Mitochondria, Muscle; Models, Molecular; Muscle, Skeletal; Mutation; NAD; NADH Dehydrogenase; Occipital Lobe; Optic Atrophy, Hereditary, Leber; Pedigree; Polymorphism, Restriction Fragment Length; Radionuclide Imaging; Rotenone; Sequence Analysis, Protein; Succinate Dehydrogenase; Visual Acuity; Visual Fields | 2004 |
Kinetic properties and metabolic contributions of yeast mitochondrial and cytosolic NADP+-specific isocitrate dehydrogenases.
Topics: Carbon; Carboxylic Acids; Catalysis; Cytosol; Electrophoresis; Genetic Complementation Test; Glucose; Glutamic Acid; Glycerol; Histidine; Hydrogen-Ion Concentration; Immunoblotting; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Kinetics; Lactates; NAD; NADP; Phenotype; Plasmids; Protein Isoforms; Saccharomyces cerevisiae; Time Factors | 2005 |
Possible involvement of glutamic and/or aspartic acid residue(s) and requirement of mitochondrial integrity for the protective effect of creatine against inhibition of cardiac mitochondrial respiration by methylglyoxal.
Topics: Alamethicin; Animals; Aspartic Acid; Binding Sites; Cell Respiration; Creatine; Electron Transport Complex I; Glutamic Acid; Goats; Intracellular Membranes; Isoxazoles; Mitochondria, Heart; NAD; NADH Dehydrogenase; Oxygen Consumption; Permeability; Protective Agents; Pyruvaldehyde; Submitochondrial Particles | 2005 |
Disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase "Asian" variant.
Topics: Aldehyde Dehydrogenase; Arginine; Binding Sites; Crystallography, X-Ray; Dimerization; DNA, Complementary; Glutamic Acid; Humans; Hydrogen Bonding; Kinetics; Lysine; Mitochondria; Models, Molecular; NAD; Protein Binding; Protein Conformation; Protein Structure, Tertiary | 2005 |
Molecular properties and enhancement of thermostability by random mutagenesis of glutamate dehydrogenase from Bacillus subtilis.
Topics: Bacillus subtilis; Cloning, Molecular; Dimerization; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Hot Temperature; Ketoglutaric Acids; Kinetics; Molecular Weight; Mutagenesis; Mutation, Missense; NAD; Substrate Specificity | 2005 |
Crystallization and avoiding the problem of hemihedral twinning in crystals of Delta1-pyrroline-5-carboxylate dehydrogenase from Thermus thermophilus.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Bacterial Proteins; Citric Acid; Crystallization; Glutamic Acid; NAD; Polymerase Chain Reaction; Thermus thermophilus; X-Ray Diffraction | 2005 |
Effect of co-existing biologically relevant molecules and ions on DNA photocleavage caused by pyrene and its derivatives.
Topics: DNA Damage; DNA, Superhelical; Electrophoresis, Agar Gel; Glutamic Acid; Histidine; Iodine; Ions; Metals; Mutagenicity Tests; NAD; Photochemistry; Pyrenes; Riboflavin; Ultraviolet Rays | 2005 |
Role of the His57-Glu214 ionic couple located in the active site of Mycobacterium tuberculosis FprA.
Topics: Amino Acid Sequence; Anaerobiosis; Binding Sites; Crystallography, X-Ray; Enzyme Stability; Flavin-Adenine Dinucleotide; Glutamic Acid; Histidine; Hot Temperature; Kinetics; Mycobacterium tuberculosis; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction | 2006 |
Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
Topics: ADP-ribosyl Cyclase 1; Amino Acid Substitution; Base Sequence; Binding Sites; Catalysis; Cold Temperature; Crystallography, X-Ray; Cyclic ADP-Ribose; Dimerization; Enzyme Stability; Glutamic Acid; Guanosine Diphosphate Sugars; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Molecular; Molecular Sequence Data; NAD; NAD+ Nucleosidase; Sequence Homology, Nucleic Acid; Serine; Static Electricity; Substrate Specificity; Water | 2006 |
Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Brain; Calcium; Glutamic Acid; Kinetics; Malates; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Molecular Sequence Data; Muscle, Skeletal; NAD | 2007 |
Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Calcium; Cell Death; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Glutamic Acid; In Vitro Techniques; Ketones; Membrane Potentials; Mitochondria; Mitochondrial Membranes; NAD; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Reactive Oxygen Species; Somatosensory Cortex | 2007 |
Catalytic mechanism of Zn2+-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu154-->Cys forms of yeast xylitol dehydrogenase.
Topics: Animals; Cysteine; D-Xylulose Reductase; Deuterium; Enzyme Inhibitors; Fungal Proteins; Glutamic Acid; Humans; Hydrogen-Ion Concentration; L-Iditol 2-Dehydrogenase; Liver; Molecular Structure; NAD; Oxidation-Reduction; Point Mutation; Sheep; Solvents; Sorbitol; Zinc | 2007 |
Gene cloning and characterization of the very large NAD-dependent l-glutamate dehydrogenase from the psychrophile Janthinobacterium lividum, isolated from cold soil.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Catalytic Domain; Chromatography, Gel; Cloning, Molecular; Conserved Sequence; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Glutamate Dehydrogenase; Glutamic Acid; Molecular Sequence Data; Molecular Weight; NAD; NADP; Oxalobacteraceae; Protein Subunits; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Soil Microbiology; Streptomyces; Substrate Specificity | 2007 |
High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates.
Topics: Animals; Dose-Response Relationship, Drug; Electron Transport Complex I; Electron Transport Complex II; Glutamic Acid; Malates; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle, Skeletal; NAD; Oxaloacetic Acid; Succinic Acid; Superoxides | 2008 |
Structural basis for the NAD-hydrolysis mechanism and the ARTT-loop plasticity of C3 exoenzymes.
Topics: ADP Ribose Transferases; Amino Acid Substitution; Asparagine; Binding Sites; Botulinum Toxins; Crystallography, X-Ray; Glutamic Acid; Hydrolysis; Mutation; NAD; Protein Conformation | 2008 |
Low potential detection of glutamate based on the electrocatalytic oxidation of NADH at thionine/single-walled carbon nanotubes composite modified electrode.
Topics: Biosensing Techniques; Catalysis; Electrochemistry; Equipment Design; Equipment Failure Analysis; Glutamic Acid; Microelectrodes; NAD; Nanotechnology; Nanotubes, Carbon; Phenothiazines; Reproducibility of Results; Sensitivity and Specificity | 2009 |
Solar energy in production of L-glutamate through visible light active photocatalyst--redox enzyme coupled bioreactor.
Topics: Bioreactors; Catalysis; Darkness; Glutamate Dehydrogenase; Glutamic Acid; Light; Molecular Conformation; NAD; Organometallic Compounds; Oxidation-Reduction; Particle Size; Photochemistry; Rhodium; Solar Energy; Time Factors; Tungsten Compounds; X-Ray Diffraction | 2008 |
Nanoparticle-supported multi-enzyme biocatalysis with in situ cofactor regeneration.
Topics: Animals; Biocatalysis; Cattle; Coenzymes; Enzymes, Immobilized; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Motion; NAD; Nanoparticles; Pyruvic Acid; Rabbits; Silicon Dioxide | 2009 |
High-sensitive glutamate biosensor based on NADH at Lauth's violet/multiwalled carbon nanotubes composite film on gold substrates.
Topics: Biosensing Techniques; Glutamate Dehydrogenase; Glutamic Acid; Gold; Microscopy, Electron, Scanning; NAD; Nanotubes, Carbon | 2009 |
CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization.
Topics: Amino Acid Substitution; Animals; Carrier Proteins; Crystallography, X-Ray; Glutamic Acid; Glycine; Mutation; NAD; Protein Conformation; Protein Multimerization; Rats; Transcription Factors | 2009 |
Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons.
Topics: 3-Hydroxybutyric Acid; Animals; Aspartic Acid; Brain Chemistry; Cells, Cultured; Cerebellum; Cytosol; Energy Metabolism; Glucose; Glutamic Acid; Ketone Bodies; Malate Dehydrogenase; Mice; NAD; Neurons; Neurotransmitter Agents; Subcellular Fractions; Synaptic Transmission | 2009 |
Colloidal nanoparticles as a wireless booster for electroenzymatic reactions.
Topics: Colloids; Electrochemical Techniques; Glutamate Dehydrogenase; Glutamic Acid; Ketoglutaric Acids; NAD; Nanoparticles; Particle Size | 2009 |
Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alkylating Agents; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Glutamic Acid; Methylnitronitrosoguanidine; Mice; Mice, Knockout; NAD; Neurons; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Time Factors | 2010 |
The unique kinetic behavior of the very large NAD-dependent glutamate dehydrogenase from Janthinobacterium lividum.
Topics: Aspartic Acid; Catalysis; Chromobacterium; Glutamate Dehydrogenase; Glutamic Acid; Ketoglutaric Acids; Kinetics; NAD; Oxalobacteraceae | 2010 |
Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.
Topics: Acid-Base Equilibrium; Alanine; Amino Acid Substitution; Binding, Competitive; Catalysis; Catalytic Domain; Glutamic Acid; Glutamine; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NAD; Recombinant Proteins; Saccharomyces cerevisiae; Saccharopine Dehydrogenases | 2010 |
Glutamate dehydrogenase and glutamine synthetase are regulated in response to nitrogen availability in Myocbacterium smegmatis.
Topics: Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamic Acid; Metabolic Networks and Pathways; Models, Biological; Mycobacterium smegmatis; NAD; NADP; Nitrogen | 2010 |
Enzymatic synthesis of some (15)N-labelled L-amino acids.
Topics: Alanine Dehydrogenase; Amino Acids; Biocatalysis; Enzymes; Glucose 1-Dehydrogenase; Glutamate Dehydrogenase; Glutamic Acid; Isotope Labeling; Keto Acids; Leucine Dehydrogenase; Mass Spectrometry; Methionine; NAD; Nitrogen Isotopes; Serine | 2010 |
Computational characterization for catalytic activities of human CD38's wild type, E226 and E146 mutants.
Topics: ADP-ribosyl Cyclase 1; Algorithms; Catalysis; Catalytic Domain; Computational Biology; Databases, Protein; Glutamic Acid; Humans; Hydrogen Bonding; Hydrolysis; Kinetics; Ligands; Mutation; NAD; Software | 2010 |
Electrochemical and spectral study on the effects of Al(III) and nano-Al13 species on glutamate dehydrogenase activity.
Topics: Aluminum; Aluminum Compounds; Animals; Biocatalysis; Cattle; Electrochemical Techniques; Electrodes; Glutamate Dehydrogenase; Glutamic Acid; Humans; Kinetics; Models, Molecular; NAD; Nanotubes; Oxidation-Reduction; Polyamines; Polyelectrolytes; Polymers; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry; Spectroscopy, Fourier Transform Infrared | 2010 |
Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia.
Topics: Aspergillus nidulans; Base Sequence; Citric Acid Cycle; DNA Primers; Ethanol; gamma-Aminobutyric Acid; Gene Expression; Gene Expression Profiling; Genes, Fungal; Glutamic Acid; Glycolysis; Lactic Acid; Metabolic Networks and Pathways; NAD; Oxygen; Protein Array Analysis; Transcription, Genetic | 2010 |
Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.
Topics: Analysis of Variance; Animals; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Guinea Pigs; Mice; Myelin Basic Protein; NAD; NADP; Nitric Oxide Synthase Type II; Oxidative Stress; Tandem Mass Spectrometry | 2011 |
Enzyme-based NAND gate for rapid electrochemical screening of traumatic brain injury in serum.
Topics: Biocatalysis; Biomarkers; Brain Injuries; Buffers; Electrochemistry; Electrodes; Glutamic Acid; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Methylene Blue; NAD; Time Factors | 2011 |
Molecular and biochemical characterisation of a Teladorsagia circumcincta glutamate dehydrogenase.
Topics: Amination; Amino Acid Sequence; Ammonia; Animals; Deamination; DNA, Complementary; DNA, Helminth; Gene Expression Regulation, Enzymologic; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; NAD; NADP; Recombinant Proteins; Sequence Alignment; Sheep; Trichostrongyloidea | 2011 |
Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models.
Topics: Acrylamides; Animals; Brain; Cell Death; Cells, Cultured; DNA, Mitochondrial; Embryo, Mammalian; Female; Glucose; Glutamic Acid; Hypoxia; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Mutation; NAD; Neurons; Neuroprotective Agents; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; Pregnancy | 2012 |
Network identification and flux quantification of glucose metabolism in Rhodobacter sphaeroides under photoheterotrophic H(2)-producing conditions.
Topics: Amino Acids; Carbon; Carbon Isotopes; Gas Chromatography-Mass Spectrometry; Gene Deletion; Gene Expression Regulation, Bacterial; Glucose; Glutamic Acid; Glycerol; Hydrogen; Light; Metabolic Networks and Pathways; NAD; Nitrogen; Oxidoreductases; Rhodobacter sphaeroides | 2012 |
Amino acid substitutions at glutamate-354 in dihydrolipoamide dehydrogenase of Escherichia coli lower the sensitivity of pyruvate dehydrogenase to NADH.
Topics: Amino Acid Substitution; Dihydrolipoamide Dehydrogenase; Escherichia coli; Escherichia coli Proteins; Ethanol; Fermentation; Glutamic Acid; Models, Molecular; Mutagenesis, Site-Directed; NAD; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 2012 |
Visible light-driven NADH regeneration sensitized by proflavine for biocatalysis.
Topics: Biocatalysis; Glutamic Acid; Light; NAD; Photosensitizing Agents; Photosynthesis; Proflavine | 2012 |
Development of a satisfactory and general continuous assay for aminotransferases by coupling with (R)-2-hydroxyglutarate dehydrogenase.
Topics: Acidaminococcus; Alcohol Oxidoreductases; Glutamic Acid; Humans; Ketoglutaric Acids; NAD; Spectrophotometry; Transaminases | 2012 |
Aralar mRNA and protein levels in neurons and astrocytes freshly isolated from young and adult mouse brain and in maturing cultured astrocytes.
Topics: Aging; Animals; Aspartic Acid; Astrocytes; Brain; Cell Separation; Cells, Cultured; Cellular Senescence; Cytoplasm; Energy Metabolism; Female; Glutamic Acid; Lactic Acid; Male; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; NAD; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Primary Cell Culture; Pyruvic Acid; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2012 |
Roles of subunit NuoK (ND4L) in the energy-transducing mechanism of Escherichia coli NDH-1 (NADH:quinone oxidoreductase).
Topics: Amino Acid Sequence; Energy Metabolism; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Immunoblotting; Membrane Proteins; Molecular Sequence Data; Mutant Proteins; Mutation; NAD; NADH Dehydrogenase; Native Polyacrylamide Gel Electrophoresis; Oxidation-Reduction; Protein Structure, Secondary; Protein Subunits; Protons | 2012 |
Further insights into the isoenzyme composition and activity of glutamate dehydrogenase in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Genes, Plant; Glutamate Dehydrogenase; Glutamic Acid; Isoenzymes; Mitochondria; Mutation; NAD; Peptides; Plant Roots | 2013 |
A biochemical correlate of dimorphism in a zygomycete Benjaminiella poitrasii: characterization of purified NAD-dependent glutamate dehydrogenase, a target for antifungal agents.
Topics: Ammonium Chloride; Antifungal Agents; Candida albicans; Catalysis; Chromatography, Agarose; Drug Evaluation, Preclinical; Fungal Proteins; Glutamate Dehydrogenase; Glutamic Acid; Histidine; Hyphae; Isoelectric Point; Ketoglutaric Acids; Lysine; Molecular Targeted Therapy; Molecular Weight; Mucorales; NAD; Phosphorylation; Protein Processing, Post-Translational; Substrate Specificity; Triazoles; Yarrowia | 2013 |
[Pharmacological correction of experimental mitochondrial dysfunction of brain stem neurons by rhytmocor and mildronate].
Topics: Adenosine Diphosphate; Animals; Electron Transport Complex I; Glutamic Acid; Injections, Subcutaneous; Malates; Male; Methylhydrazines; Mitochondria; NAD; Neurons; Oxidation-Reduction; Oxidative Phosphorylation; Propafenone; Rats; Rats, Wistar; Rotenone; Succinic Acid | 2013 |
A single amino acid residue controls ROS production in the respiratory Complex I from Escherichia coli.
Topics: Catalytic Domain; Electron Transport Complex I; Escherichia coli; Escherichia coli Proteins; Flavin Mononucleotide; Glutamic Acid; Models, Molecular; Mutation; NAD; Oxidation-Reduction; Oxygen; Protein Binding; Quinone Reductases; Reactive Oxygen Species; Ubiquinone | 2013 |
Conditioned medium of human adipose-derived mesenchymal stem cells mediates protection in neurons following glutamate excitotoxicity by regulating energy metabolism and GAP-43 expression.
Topics: Adenosine Triphosphate; Adipose Tissue; Adult; Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Culture Media, Conditioned; Energy Metabolism; GAP-43 Protein; Glutamic Acid; Humans; Membrane Potential, Mitochondrial; Mesenchymal Stem Cells; NAD; Neurites; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley | 2014 |
Synthesis of L-2,3-diaminopropionic acid, a siderophore and antibiotic precursor.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Alanine; Binding Sites; Catalytic Domain; Citrates; Crystallography, X-Ray; Glutamic Acid; Hydrolysis; Ketoglutaric Acids; Molecular Dynamics Simulation; NAD; Phosphoserine; Recombinant Proteins; Siderophores; Staphylococcus aureus | 2014 |
Arg279 is the key regulator of coenzyme selectivity in the flavin-dependent ornithine monooxygenase SidA.
Topics: Alanine; Arginine; Aspergillus fumigatus; Escherichia coli; Flavins; Fungal Proteins; Glutamic Acid; Hydroxylation; Kinetics; Mixed Function Oxygenases; Models, Molecular; Mutagenesis, Site-Directed; NAD; NADP; Ornithine; Oxidation-Reduction; Oxygen; Protein Conformation; Recombinant Fusion Proteins; Static Electricity; Substrate Specificity | 2014 |
Silicon nanowire photocathodes for light-driven electroenzymatic synthesis.
Topics: Electrochemistry; Electrodes; Glutamic Acid; Ketoglutaric Acids; Light; Metal Nanoparticles; NAD; Nanowires; Platinum; Silicon | 2014 |
The effects of NAD+ on apoptotic neuronal death and mitochondrial biogenesis and function after glutamate excitotoxicity.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Cells, Cultured; Glutamic Acid; Membrane Potential, Mitochondrial; Mice; Mitochondria; NAD; Neurons | 2014 |
Residues that influence coenzyme preference in the aldehyde dehydrogenases.
Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; Amino Acids; Binding Sites; Coenzymes; Glutamic Acid; Humans; Kinetics; Models, Molecular; NAD; NADP; Static Electricity; Substrate Specificity | 2015 |
Monitoring of the velocity of high-affinity glutamate uptake by isolated brain nerve terminals using amperometric glutamate biosensor.
Topics: Animals; Biosensing Techniques; Brain; Electrodes; Glutamate Dehydrogenase; Glutamic Acid; Male; NAD; Oxidoreductases; Platinum; Rats; Rats, Wistar; Synaptosomes | 2015 |
L-NAME combats excitotoxicity and recuperates neurological deficits in MCAO/R rats.
Topics: Adenosine Triphosphate; Animals; Cerebral Infarction; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamate-Ammonia Ligase; Glutamic Acid; Infarction, Middle Cerebral Artery; Interleukin-10; Male; NAD; Nervous System Diseases; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2015 |
Respiration and substrate transport rates as well as reactive oxygen species production distinguish mitochondria from brain and liver.
Topics: Animals; Aspartic Acid; Biological Transport; Brain; Cell Respiration; Dicarboxylic Acid Transporters; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Gene Expression Regulation; Glutamic Acid; Kinetics; Liver; Malates; Membrane Potential, Mitochondrial; Mice; Mitochondria, Liver; NAD; Organ Specificity; Reactive Oxygen Species; Succinic Acid | 2015 |
Reactive oxygen species production in cardiac mitochondria after complex I inhibition: Modulation by substrate-dependent regulation of the NADH/NAD(+) ratio.
Topics: Animals; Aspartate Aminotransferases; Coenzyme A; Electron Transport Complex I; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Malate Dehydrogenase; Malates; Mitochondria, Heart; NAD; Oxygen Consumption; Pyridines; Rabbits; Reactive Oxygen Species; Rotenone; Substrate Specificity | 2016 |
Increasing the production of (R)-3-hydroxybutyrate in recombinant Escherichia coli by improved cofactor supply.
Topics: 3-Hydroxybutyric Acid; Alcohol Oxidoreductases; Bacterial Proteins; Escherichia coli; Glutamic Acid; Halomonas; NAD; Nitrogen; Phylogeny; Plasmids; Recombinant Proteins; Stereoisomerism | 2016 |
Defining and Detecting Complex Peak Relationships in Mass Spectral Data: The Mz.unity Algorithm.
Topics: Algorithms; Glutamic Acid; Mass Spectrometry; Metabolomics; NAD; Software | 2016 |
Identification of a Novel Activator of Mammalian Glutamate Dehydrogenase.
Topics: Adenosine Diphosphate; Allosteric Regulation; Amino Acids, Cyclic; Animals; Binding, Competitive; Biocatalysis; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Kinetics; Models, Molecular; NAD; Protein Binding; Protein Domains; Pyrimidines; Spectrometry, Fluorescence; Sulfonamides | 2016 |
Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC.
Topics: A549 Cells; Adenosine Triphosphate; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Death; Cell Proliferation; Cell Survival; Cytosol; Drug Synergism; Fluorouracil; Gene Knockdown Techniques; Glutamic Acid; Glutaminase; Glutamine; Lung Neoplasms; Malates; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; NAD; Oxidation-Reduction; Sulfides; Thiadiazoles; Thymidylate Synthase; Xenograft Model Antitumor Assays | 2016 |
Cofactor recycling for co-production of 1,3-propanediol and glutamate by metabolically engineered Corynebacterium glutamicum.
Topics: Aerobiosis; Biosynthetic Pathways; Coenzymes; Corynebacterium glutamicum; Glutamic Acid; Glycerol; Hydro-Lyases; Metabolic Engineering; NAD; Propylene Glycols; Substrate Specificity | 2017 |
Simultaneous Measurement of Glucose-6-phosphate 3-Dehydrogenase (NtdC) Catalysis and the Nonenzymatic Reaction of Its Product: Kinetics and Isotope Effects on the First Step in Kanosamine Biosynthesis.
Topics: Bacillus subtilis; Bacterial Proteins; Biocatalysis; Deuterium; Escherichia coli; Gene Expression Regulation, Bacterial; Glucosamine; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; NAD; Operon; Oxidation-Reduction; Protons; Recombinant Proteins; Thermodynamics | 2017 |
Structure and characterization of a class 3B proline utilization A: Ligand-induced dimerization and importance of the C-terminal domain for catalysis.
Topics: Bacterial Proteins; Catalysis; Corynebacterium; Crystallography, X-Ray; Glutamic Acid; Membrane Proteins; NAD; Oxidation-Reduction; Proline; Protein Domains; Protein Multimerization; Structure-Activity Relationship | 2017 |
Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Energy Metabolism; Gene Expression; Glucose; Glutamic Acid; Glutamine; Glycolysis; Heterografts; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lung Neoplasms; Mice; Mitochondria; Models, Biological; NAD; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species; Receptors, Metabotropic Glutamate; Riluzole | 2017 |
The key role of glutamate 172 in the mechanism of type II NADH:quinone oxidoreductase of Staphylococcus aureus.
Topics: Bacterial Proteins; Benzoquinones; Glutamic Acid; NAD; NADH Dehydrogenase; Oxidation-Reduction; Protein Binding; Quinone Reductases; Staphylococcus aureus | 2017 |
Exogenous γ-aminobutyric acid treatment improves the cold tolerance of zucchini fruit during postharvest storage.
Topics: 4-Aminobutyrate Transaminase; Adenosine Triphosphate; Alanine; Amine Oxidase (Copper-Containing); Cell Death; Cold Temperature; Cucurbita; Food Storage; Fruit; Fumarates; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Malates; NAD; Proline; Putrescine | 2019 |
TIR domains of plant immune receptors are NAD
Topics: Amino Acid Substitution; Arabidopsis; Arabidopsis Proteins; Armadillo Domain Proteins; Biomarkers; Catalytic Domain; Cell Death; Conserved Sequence; Cyclic ADP-Ribose; Cytoskeletal Proteins; DNA-Binding Proteins; Glutamic Acid; Host-Pathogen Interactions; NAD; NAD+ Nucleosidase; Receptors, Immunologic | 2019 |
Molecular characteristics associated with ferroptosis in hepatocellular carcinoma progression.
Topics: Activating Transcription Factor 3; Alanine; Carcinoma, Hepatocellular; Disease Progression; Ferroptosis; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Glutamic Acid; Heat-Shock Proteins; Humans; Liver Neoplasms; MAP Kinase Signaling System; Molecular Chaperones; NAD; Survival Rate | 2021 |
Optimal pH shift of the NADH oxidase from Lactobacillus rhamnosus with a single mutation.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Lacticaseibacillus rhamnosus; Models, Molecular; Molecular Docking Simulation; Multienzyme Complexes; Mutagenesis, Site-Directed; NAD; NADH, NADPH Oxidoreductases; Protein Conformation; Protein Engineering; Substrate Specificity | 2021 |
Alteration of cofactor specificity of the acrylyl-CoA reductase from Escherichia coli.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Mutagenesis, Site-Directed; NAD; NADP; Protein Engineering; Quinone Reductases; Serine; Substrate Specificity | 2021 |
Comparative Study of Functional Changes in Heart Mitochondria in Two Modes of Epinephrine Exposure Modeling Myocardial Injury in Rats.
Topics: Adenosine Triphosphate; Animals; Calcium; Cardiomyopathies; Cations, Divalent; Disease Models, Animal; Electron Transport Complex II; Epinephrine; Glutamic Acid; Malates; Male; Mitochondria, Heart; Myocardium; Myocytes, Cardiac; NAD; Oxidative Phosphorylation; Rats; Rats, Wistar; Succinic Acid | 2021 |
PI3K Pathway Inhibition with NVP-BEZ235 Hinders Glycolytic Metabolism in Glioblastoma Multiforme Cells.
Topics: Brain Neoplasms; Cell Line, Tumor; Forkhead Box Protein O1; Gene Expression Regulation, Neoplastic; Gene Ontology; Glioblastoma; Glucose; Glutamic Acid; Glycolysis; Humans; Imidazoles; Kaplan-Meier Estimate; Lactic Acid; NAD; Phosphatidylinositol 3-Kinases; Prognosis; Protein Kinase Inhibitors; Quinolines; Signal Transduction | 2021 |
Engineering of phenylalanine dehydrogenase from Thermoactinomyces intermedius for the production of a novel homoglutamate.
Topics: Amino Acid Oxidoreductases; Glutamic Acid; NAD; Protein Engineering; Thermoactinomyces | 2022 |
Osmundacetone modulates mitochondrial metabolism in non-small cell lung cancer cells by hijacking the glutamine/glutamate/α-KG metabolic axis.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; G2 Phase Cell Cycle Checkpoints; Glutamic Acid; Glutamine; Humans; Ketones; Lung Neoplasms; Mice; Mitochondria; NAD | 2022 |
A versatile optofluidic microreactor for artificial photosynthesis induced coenzyme regeneration and L-glutamate synthesis.
Topics: Catalysis; Coenzymes; Glutamic Acid; NAD; Photosynthesis; Regeneration | 2022 |
Disruption of mitochondrial functions involving mitochondrial permeability transition pore opening caused by maleic acid in rat kidney.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Glutamic Acid; HEK293 Cells; Humans; Kidney; Kidney Failure, Chronic; Malates; Maleates; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NAD; Permeability; Propidium; Propionic Acidemia; Rats; Rats, Wistar | 2022 |
Reversible Glutamate Coordination to High-Valent Nickel Protects the Active Site of a [NiFe] Hydrogenase from Oxygen.
Topics: Alanine; Aspartic Acid; Catalytic Domain; Glutamic Acid; Glutamine; Hydrogenase; Hydrogenophilaceae; Iron; Ligands; NAD; Nickel; Oxidation-Reduction; Oxygen | 2022 |
Bidirectional sequestration between a bacterial hibernation factor and a glutamate metabolizing protein.
Topics: Bacteria; Glucose; Glutamic Acid; Hibernation; Humans; NAD; Oxidoreductases; Ribosomal Proteins; Staphylococcus aureus; Virulence Factors | 2022 |
EPO has multiple positive effects on astrocytes in an experimental model of ischemia.
Topics: Astrocytes; Brain Injuries, Traumatic; Erythropoietin; Glutamic Acid; Humans; Ischemia; Ischemic Stroke; Models, Theoretical; NAD; Sodium-Potassium-Exchanging ATPase | 2023 |
Structural and functional studies of Arabidopsis thaliana glutamate dehydrogenase isoform 2 demonstrate enzyme dynamics and identify its calcium binding site.
Topics: Ammonia; Arabidopsis; Binding Sites; Calcium; Coenzymes; Glutamate Dehydrogenase; Glutamic Acid; Isoenzymes; NAD | 2023 |
Development of a 2-hydroxyglutarate production system by Corynebacterium glutamicum.
Topics: Biotin; Corynebacterium glutamicum; Glutamic Acid; NAD; Nitrogen | 2023 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |