nad has been researched along with folic acid in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 52 (75.36) | 18.7374 |
| 1990's | 2 (2.90) | 18.2507 |
| 2000's | 6 (8.70) | 29.6817 |
| 2010's | 7 (10.14) | 24.3611 |
| 2020's | 2 (2.90) | 2.80 |
| Authors | Studies |
|---|---|
| Roberts, GC | 1 |
| Kaufman, BT; Subramanian, S | 1 |
| Krumdieck, CL; White, WE; Yielding, LK | 1 |
| Greenfield, NJ | 1 |
| James, SJ; Yin, L | 1 |
| Morrison, JF; Stone, SR | 1 |
| Kikuchi, G; Yoshida, T | 1 |
| Frisell, WR; Randolph, VM | 1 |
| Bhat, JV; Nambudiri, AM | 1 |
| Gawthorne, JM; Osborne-White, WS; Smith, RM | 1 |
| Gawthorne, JM; Smith, RM | 1 |
| Foster, MA; Guest, JR; Woods, DD | 1 |
| Galloway, E; Kutzbach, C; Stokstad, EL | 1 |
| Gutteridge, WE; Jaffe, JJ; McCormack, JJ | 1 |
| Landauer, W; Wakasugi, N | 1 |
| Kikuchi, G; Motokawa, Y | 1 |
| Kikuchi, G; Kochi, H; Sato, N; Sato, T | 1 |
| Daniel, LJ; Griffiths, JM | 1 |
| Kung, HF; Wagner, C | 1 |
| Hanna, ML; Taylor, RT | 1 |
| Ritari, SJ; Rosales, F; Sakami, W | 1 |
| Herman, RH; Rosensweig, NS; Stifel, FB | 1 |
| Goodman, JI; Tephly, TR | 1 |
| Summers, MR | 1 |
| Kawai, M; Scrimgeour, KG | 1 |
| Battat, E; Goldberg, I; Mateles, RI | 1 |
| Bush, ME; Donaldson, KO | 1 |
| Jaffe, JJ; McCormack, JJ | 1 |
| Andreeva, NA; Efimova, RI | 1 |
| Burchall, J | 1 |
| Kaufman, BT | 1 |
| Burchall, JJ; Hitchings, GH | 1 |
| Kikuchi, G; Kochi, H | 1 |
| Butt, VS; Vaughan, PF | 1 |
| Leclerc, M | 1 |
| Bertino, JR; Cashmore, AR; Hillcoat, BL | 1 |
| Kutzbach, C; Stokstad, EL | 1 |
| Turner, JM; Willetts, AJ | 1 |
| Greenfield, NJ; Hirshfield, JM; Hoogsteen, K; Poe, M; Williams, MN | 1 |
| Drummond, D; MacKenzie, RE; Smith, S | 1 |
| Collins, TD; McMartin, KE | 1 |
| Allen, RH; Henderson, LM; Hoyumpa, AM; Middleton, HM; Rose, RC; Rosenberg, IH | 1 |
| Reynolds, MG; Roos, DS | 1 |
| Badii, R; Basran, J; Casarotto, MG; Roberts, GC; Sze, KH | 1 |
| Ballou, DP; Ludwig, ML; Matthews, RG; Trimmer, EE | 1 |
| OERIU, S | 1 |
| DEPPE, WM; JOUBERT, SM; MCKECHNIE, JK | 1 |
| BROWN, GM; REYNOLDS, JJ | 1 |
| LANGER, BW | 1 |
| BUCHANAN, JM; ELFORD, HL; LOUGHLIN, RE | 1 |
| KENNEDY, EP; LINDBERG, M; TIETZ, A | 1 |
| BRESSLER, R; KATZ, RI | 1 |
| MAINWARING, WI; WILLIAMS, DC | 1 |
| LAMBE, RF; WILLIAMS, DC | 1 |
| Ballou, DP; Brinker, DR; Casas, KR; Galloway, LJ; Scannell, SA; Trimmer, EE | 1 |
| Ainavarapu, SR; Badilla, CL; Fernandez, JM; Li, L | 1 |
| Ludwig, ML; Pejchal, R; Sargeant, R | 1 |
| Ainavarapu, SR; Fernandez, JM; Li, L | 1 |
| Ballou, DP; Furtado, VC; Lee, MN; Nikolova, AP; Phung, NL; Still, BR; Takawira, D; Tanner, JJ; Thorstad, MK; Trimmer, EE | 1 |
| Biparva, P; Hatami, M; Karimi-Maleh, H | 1 |
| Appling, DR; Bryant, JD; Momb, J; Shin, M | 1 |
| Khalilzadeh, MA; Ojani, R; Raoof, JB; Teymoori, N | 1 |
| Bilgin, A; Croft, KD; Grant, R; Guest, J; Hokin, B; Mori, TA | 1 |
| Andersson, Y; Bonagas, N; Dahllund, L; Färnegårdh, K; Gustafsson, NM; Gustafsson, R; Häggblad, M; Helleday, T; Henriksson, M; Homan, E; Jemth, AS; Llona-Minguez, S; Loseva, O; Stenmark, P; Wiita, E | 1 |
| Bushel, P; Chandel, N; Grenet, D; Li, J; Lozoya, OA; Martinez-Reyes, I; Santos, JH; Wang, T; Woychik, RP | 1 |
| Heske, CM; Issaq, SH | 1 |
| Bruning, JB; Jayapalan, JJ; Jovcevski, B; Maenpuen, S; Pantong, W; Pederick, JL; Salaemae, W; Tinikul, R; Wegener, KL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
3 review(s) available for nad and folic acid
| Article | Year |
|---|---|
Inhibition of folate biosynthesis and function as a basis for chemotherapy.
Topics: Aminobenzoates; Animals; Binding Sites; Biological Transport; Drug Resistance, Microbial; Drug Synergism; Escherichia coli; Folic Acid; Folic Acid Antagonists; Glutamates; Guinea Pigs; Humans; Lactobacillus; Leucovorin; Methotrexate; NAD; NADP; Pteridines; Pyrimidines; Rabbits; Rats; Sulfonamides | 1965 |
BIOGENESIS OF THE WATER-SOLUBLE VITAMINS.
Topics: Alanine; Benzimidazoles; Biotin; Coenzyme A; Flavins; Folic Acid; Hydroxocobalamin; Metabolism; NAD; Niacin; Nicotinic Acids; Nucleosides; Oxidoreductases; Pantothenic Acid; Phosphotransferases; Pterins; Pyridoxine; Research; Riboflavin; Thiamine; Thiamine Pyrophosphate; Vitamin B 12; Vitamins | 1963 |
Targeting metabolic dependencies in pediatric cancer.
Topics: Amino Acids; Antineoplastic Agents; Child; Folic Acid; Glycolysis; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; NAD; Neoplasms; Oxidative Phosphorylation; Polyamines | 2020 |
66 other study(ies) available for nad and folic acid
| Article | Year |
|---|---|
The binding of substrates and inhibitors to dihydrofolate reductase.
Topics: Binding Sites; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Kinetics; Ligands; NAD; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase | 1975 |
Interaction of methotrexate, folates, and pyridine nucleotides with dihydrofolate reductase: calorimetric and spectroscopic binding studies.
Topics: Animals; Calorimetry; Chickens; Folic Acid; Liver; Methotrexate; NAD; NADP; Protein Binding; Protons; Spectrum Analysis; Tetrahydrofolate Dehydrogenase; Thermodynamics | 1978 |
Folates as inhibitors of glutamate dehydrogenase.
Topics: Aminobenzoates; Animals; Binding Sites; Cattle; Folic Acid; Glutamate Dehydrogenase; Glutamates; Kinetics; Liver; Methotrexate; NAD; Peptides; Pterins; Tetrahydrofolates | 1976 |
Circular dichroism studies of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli B, MB 1428: ternary complexes.
Topics: Adenosine Diphosphate Sugars; Binding Sites; Circular Dichroism; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Methotrexate; NAD; NADP; Nicotinamide Mononucleotide; Protein Binding; Protein Conformation; Ribose; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase | 1975 |
Diet-induced DNA damage and altered nucleotide metabolism in lymphocytes from methyl-donor-deficient rats.
Topics: Animals; Choline; Choline Deficiency; Deoxyuridine; Diet; DNA Damage; DNA Replication; Folic Acid; Folic Acid Deficiency; Liver; Lymphocytes; Male; Methionine; NAD; Nucleotides; Rats; Rats, Inbred F344; Reference Values; RNA; Spleen; Thymidine | 1989 |
Dihydrofolate reductase from Escherichia coli: the kinetic mechanism with NADPH and reduced acetylpyridine adenine dinucleotide phosphate as substrates.
Topics: Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Tetrahydrofolate Dehydrogenase; Viscosity | 1988 |
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid | 1971 |
Effect of adenine nucleotides on the oxidation of methyl groups in liver mitochondria.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Carbon Dioxide; Dinitrophenols; Folic Acid; Formaldehyde; Formates; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylation; Mitochondria, Liver; Mitochondrial Swelling; NAD; NADP; Oxygen Consumption; Rats; Rotenone; Sarcosine; Semicarbazides; Serine | 1973 |
Conversion of p-coumarate into caffeate by Streptomyces nigrifaciens. Purification and properties of the hydroxylating enzyme.
Topics: Ascorbic Acid; Chromatography, Gel; Cinnamates; Copper; Coumarins; Electrophoresis, Polyacrylamide Gel; Folic Acid; Hydroxylation; Mixed Function Oxygenases; Molecular Weight; NAD; NADP; Oxidoreductases; Phenols; Streptomyces | 1972 |
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on liver constituents associated with folate metabolism.
Topics: Adenosine Triphosphate; Animals; Azo Compounds; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Enterococcus faecalis; Female; FIGLU Test; Folic Acid; Glutarates; Lacticaseibacillus casei; Liver; Methionine; NAD; NADP; Pediococcus; Potassium; Sheep; Sodium; Tetrahydrofolates; Vitamin B 12 Deficiency | 1974 |
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on methotrexate transport and the activity of enzymes associated with folate metabolism in liver.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Female; Folic Acid; Homocysteine; Liver; Membranes; Methionine; Methotrexate; Methyltransferases; NAD; NADP; S-Adenosylmethionine; Serum Albumin, Bovine; Sheep; Tetrahydrofolate Dehydrogenase; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Methyl derivatives of folic acid as intermediates in the methylation of homocysteine by Escherichia coli.
Topics: Alkylation; Chromatography; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; In Vitro Techniques; Methionine; Molecular Biology; Mutation; NAD | 1964 |
Influence of vitamin B12 and methionine on levels of folic acid compounds and folate enzymes in rat liver.
Topics: Animals; Biological Assay; Female; Folic Acid; Liver; Methionine; NAD; Oxidoreductases; Pregnancy; Pregnancy, Animal; Rats; Transferases; Vitamin B 12 | 1967 |
Presence and properties of dihydrofolate reductases within the genus Trypanosoma.
Topics: Aminopterin; Animals; Depression, Chemical; Folic Acid; Methotrexate; NAD; Tetrahydrofolate Dehydrogenase; Trypanosoma | 1968 |
Teratological studies with sulphonamides and their implications.
Topics: Abnormalities, Drug-Induced; Adenine Nucleotides; Animals; Carbonic Anhydrase Inhibitors; Chick Embryo; Chloramines; Dichlorphenamide; Drug Synergism; Folic Acid; Methazolamide; NAD; Pyridines; Sulfanilamides; Sulfonamides; Time Factors | 1968 |
Glycine metabolism by rat liver mitochondria. II. Methylene tetrahydrofolate as the direct on carbon donor in the reaction of glycine synthesis.
Topics: Animals; Arsenic; Carbon; Carbon Isotopes; Folic Acid; Glycine; In Vitro Techniques; Mitochondria, Liver; NAD; Pyridoxal Phosphate; Rats; Sulfhydryl Compounds; Time Factors; Transferases | 1969 |
Glycine metabolism by rat liver mitochondria. 3. The glycine cleavage and the exchange of carboxyl carbon of glycine with bicarbonate.
Topics: Ammonia; Animals; Arsenic; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Folic Acid; Glycine; In Vitro Techniques; Kinetics; Mitochondria, Liver; NAD; Pyridoxal Phosphate; Rats; Serine; Sulfhydryl Compounds; Transferases | 1969 |
Methionine biosynthesis in Ochromonas malhamensis.
Topics: Adenosine Triphosphate; Alcohols; Carbon Isotopes; Cyanides; Enzyme Activation; Eukaryota; Flavin Mononucleotide; Folic Acid; Homocysteine; Kinetics; Light; Magnesium; Methionine; NAD; Oxygen; Sulfur; Transferases; Vitamin B 12 | 1969 |
The enzymatic synthesis of N-methylalanine.
Topics: Adenosine Triphosphate; Alanine; Amines; Autoradiography; Carbon Isotopes; Chromatography, Gel; Chromatography, Thin Layer; Crystallization; Electrophoresis; Folic Acid; Glutamates; Magnesium; NAD; Paper; Pseudomonas; Pyruvates; Serine | 1970 |
Escherichia coli B cobalamin methyltransferase: ability of diaphorases and lipoamide dehydrogenases to function as reducing agents.
Topics: Alcohols; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Dihydrolipoamide Dehydrogenase; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Iodoacetates; Methionine; Methylation; Myocardium; NAD; Spectrophotometry; Sulfhydryl Compounds; Swine; Transferases; Vitamin B 12 | 1970 |
Formation of the N5-methyltetrahydrofolate-homocysteine methyltransferase holoenzyme from apoenzyme and adenosyl-B 12.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Enzyme Precursors; Escherichia coli; Folic Acid; Homocysteine; Methionine; NAD; Transferases; Vitamin B 12 | 1970 |
Dietary regulation of glycolytic enzymes. XI. Effect of inhibitors of protein synthesis on the adaptation of certain jejunal glycolytic and folate-metabolizing enzymes to diet and sex steroids.
Topics: Aldehyde-Lyases; Animals; Caseins; Dactinomycin; Dietary Carbohydrates; Dietary Proteins; Enzyme Induction; Estradiol; Ethionine; Fasting; Female; Folic Acid; Fructose; Fructosephosphates; Glycolysis; Jejunum; Male; Metabolism; NAD; Oxidoreductases; Pyruvate Kinase; Rats; RNA; Serine; Testosterone; Time Factors; Transferases | 1971 |
A comparison of rat and human liver formaldehyde dehydrogenase.
Topics: Alcohol Oxidoreductases; Aldehydes; Animals; Calcium Phosphates; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Enzyme Activation; Female; Folic Acid; Formaldehyde; Gels; Glutathione; Humans; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Liver; Macromolecular Substances; Male; Molecular Weight; NAD; Oxidoreductases; Phenanthrolines; Rats | 1971 |
Reaction of N-bromosuccinimide with reduced ring systems. Apparent protection of glutamate dehydrogenase by reduced nicotinamide-adenine dinucleotide.
Topics: Bromine; Chemical Phenomena; Chemistry; Folic Acid; Glutamate Dehydrogenase; NAD; Oxidation-Reduction; Pteridines; Pyrrolidinones; Spectrophotometry; Succinimides; Ultraviolet Rays | 1972 |
Reduction of folate and dihydrofolate by dithionite.
Topics: Chemical Phenomena; Chemistry; Folic Acid; Hydrogen-Ion Concentration; Kinetics; NAD; Nitrophenols; Osmolar Concentration; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Sulfites; Temperature | 1972 |
Megavitamin and orthomolecular therapy in psychiatry.
Topics: Aged; Alcoholism; Ascorbic Acid; Avitaminosis; Child; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Folic Acid; Humans; Mental Disorders; NAD; Nicotinic Acids; Psychiatry; Pyridoxine; Schizophrenia; Substance-Related Disorders; Vitamin B 12; Vitamins | 1974 |
Growth of Pseudomonas C on C1 compounds: continuoous culture.
Topics: Aminobenzoates; Carbon Dioxide; Carbon Radioisotopes; Folic Acid; Formaldehyde; Formates; Glycine; Methanol; NAD; Polysorbates; Pseudomonas; Serine | 1974 |
Tetrahydrofolate dehydrogenase from bakers' yeast.
Topics: Chromatography; Folic Acid; In Vitro Techniques; Mercaptoethanol; NAD; NADP; Saccharomyces; Spectrophotometry; Tetrahydrofolate Dehydrogenase | 1965 |
Dihydrofolate reductase from Trypanosoma equiperdum. I. Isolation, partial purification, and properties.
Topics: Aminopterin; Animals; Folic Acid; Folic Acid Antagonists; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Methotrexate; NAD; NADP; Pyrimethamine; Rats; Tetrahydrofolate Dehydrogenase; Trypanosoma | 1967 |
[An aminopterine-resistant enzymatic way of reduction of folic acid to a coenzymic form, discovered in plants].
Topics: Aminopterin; Chromatography; Chromatography, Gel; Coenzymes; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; NAD; NADP; Plants | 1966 |
Protection of microbial dihydrofolate reductase against inactivation by pronase.
Topics: Amines; Benzoates; Calcium; Chromatography; Endopeptidases; Escherichia coli; Folic Acid; Folic Acid Antagonists; Formates; Glutamates; Heterocyclic Compounds; Kinetics; Leucovorin; NAD; NADP; Protein Binding; Pteridines | 1968 |
Studies on dihydrofolic reductase. 3. Activation of the chicken liver enzyme by urea and thiourea.
Topics: Animals; Chickens; Folic Acid; Formamides; Glycerol; Guanidines; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; NADP; Optical Rotatory Dispersion; Protein Binding; Tetrahydrofolate Dehydrogenase; Thiourea; Urea | 1968 |
Reactions of glycine synthesis and glycine cleavage catalyzed by extracts of Arthrobacter globiformis grown on glycine.
Topics: Ammonium Chloride; Arthrobacter; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Folic Acid; Formaldehyde; Glutathione; Glycine; Ion Exchange Resins; Kinetics; Mitochondria, Liver; NAD; NADP; Pyridoxal Phosphate; Serine; Sulfhydryl Compounds | 1969 |
The hydroxylation of p-coumaric acid by an enzyme from leaves of spinach beet (Beta vulgaris L.).
Topics: Ascorbic Acid; Catechol Oxidase; Coumarins; Folic Acid; Mixed Function Oxygenases; NAD; NADP; Plants; Pteridines | 1969 |
[Coenzymes (vitamins)].
Topics: Ascorbic Acid; Biotin; Chemical Phenomena; Chemistry; Coenzyme A; Coenzymes; Cytochromes; Flavin-Adenine Dinucleotide; Folic Acid; Glutathione; NAD; NADP; Nucleosides; Pyridoxine; Thiamine; Thioctic Acid; Ubiquinone; Vitamins | 1970 |
"Induction" of dihydrofolate reductase: purification and properties of the "induced" human erythrocyte and leukocyte enzyme and normal bone marrow enzyme.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromatography; Enzyme Activation; Enzyme Induction; Erythrocytes; Folic Acid; Humans; Hydrogen-Ion Concentration; Immune Sera; Leukemia L1210; Leukocytes; Methotrexate; Molecular Weight; NAD; NADP; Neoplasms; Protein Denaturation; Tetrahydrofolate Dehydrogenase | 1970 |
Mammalian methylenetetrahydrofolate reductase. Partial purification, properties, and inhibition by S-adenosylmethionine.
Topics: Adenosine; Alcohol Oxidoreductases; Ammonium Sulfate; Animals; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Drug Stability; Flavin-Adenine Dinucleotide; Folic Acid; Formaldehyde; Homocysteine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; NADP; Rats; S-Adenosylmethionine; Spectrophotometry; Swine; Vitamin K | 1971 |
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases | 1971 |
Dihydrofolate reductase. Purification and characterization of the enzyme from an amethopterin-resistant mutant of Escherichia coli.
Topics: Amino Acids; Chromatography, Affinity; Chromatography, Gel; Cyanogen Bromide; Dansyl Compounds; Drug Resistance, Microbial; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Methotrexate; NAD; NADP; Osmolar Concentration; Potassium Chloride; Sodium Chloride; Tetrahydrofolate Dehydrogenase; Ultracentrifugation | 1972 |
Methylenetetrahydrofolate dehydrogenase - methenyltetrahydrofolate cyclohydrolase - formyltetrahydrofolate synthetase from porcine liver: evidence to support a common dehydrogenase-cyclohydrolase site.
Topics: Aminohydrolases; Animals; Binding Sites; Diethyl Pyrocarbonate; Folic Acid; Formate-Tetrahydrofolate Ligase; Kinetics; Ligases; Liver; Methenyltetrahydrofolate Cyclohydrolase; Methylenetetrahydrofolate Dehydrogenase (NADP); Multienzyme Complexes; NAD; NADP; Oxidoreductases; Phenylglyoxal; Swine | 1983 |
Relationship of alcohol metabolism to folate deficiency produced by ethanol in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Folic Acid; Folic Acid Deficiency; Male; Metabolic Clearance Rate; Methanol; NAD; Rats; Rats, Inbred Strains | 1983 |
Transport and metabolism of water-soluble vitamins in intestine and kidney.
Topics: Animals; Ascorbic Acid; Biological Transport; Coenzyme A; Digestion; Folic Acid; Humans; Intestinal Absorption; Intestinal Mucosa; Kidney; Microvilli; NAD; Pyridoxine; Thiamine; Vitamin B 12; Vitamins | 1984 |
A biochemical and genetic model for parasite resistance to antifolates. Toxoplasma gondii provides insights into pyrimethamine and cycloguanil resistance in Plasmodium falciparum.
Topics: Alleles; Animals; Binding Sites; Drug Resistance; Escherichia coli; Folic Acid; Folic Acid Antagonists; Genetic Complementation Test; Kinetics; Models, Genetic; Models, Molecular; Mutagenesis, Site-Directed; NAD; Plasmodium falciparum; Proguanil; Pyrimethamine; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Toxoplasma; Triazines | 1998 |
Direct measurement of the pKa of aspartic acid 26 in Lactobacillus casei dihydrofolate reductase: implications for the catalytic mechanism.
Topics: Apoenzymes; Aspartic Acid; Catalysis; Folic Acid; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Macromolecular Substances; NAD; Tetrahydrofolate Dehydrogenase | 1999 |
Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Enzyme Activation; Escherichia coli; Folic Acid; Glutamic Acid; Glutamine; Kinetics; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Spectrophotometry; Vitamin K | 2001 |
[Research on the relation between vitamin coenzymes and corresponding enzymes in relation to the age of the animal and under the influence of certain substances proper to the organism].
Topics: Acetylesterase; Adenine Nucleotides; Aging; Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Coenzymes; Cysteine; D-Alanine Transaminase; Folic Acid; Humans; NAD; Niacin; Niacinamide; Pantothenic Acid; Pyridoxine; Riboflavin; Thiamine; Thiamine Pyrophosphate; Vitamins | 1963 |
SOME ASPECTS OF INTERMEDIARY METABOLISM IN AFRICAN (BANTU) PORPHYRIA (PORPHYRIA CUTANEA TARDA SYMPTOMATICA).
Topics: Black People; Blood; Citrates; Citric Acid Cycle; Folic Acid; Humans; Ketoglutaric Acids; Metabolism; NAD; Porphyria Cutanea Tarda; Porphyrias; Pyruvates; South Africa; Vitamin B Complex | 1963 |
ORGAN AND INTRACELLULAR LOCATION OF THE METHIONINE METHYL GROUP SYNTHESIZING SYSTEM OF THE RAT.
Topics: Adenosine Triphosphate; Brain; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Glucose; Homocysteine; Kidney; Leuconostoc; Liver; Magnesium; Methionine; Muscles; NAD; Pectoralis Muscles; Proteins; Pyridoxal Phosphate; Rats; Research; Serine; Spectrophotometry | 1964 |
ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. VII. ISOLATION OF A COBALAMIN-CONTAINING TRANSMETHYLASE (5-METHYLTETRAHYDRO-FOLATE-HOMOCYSTEINE) FROM MAMMALIAN LIVER.
Topics: Animals; Chromatography; Corrinoids; Flavin-Adenine Dinucleotide; Folic Acid; Glutamates; Homocysteine; Liver; Methionine; Methyltransferases; NAD; NADP; Protamines; Research; Swine; Transferases; Vitamin B 12 | 1964 |
A NEW PTERIDINE-REQUIRING ENZYME SYSTEM FOR THE OXIDATION OF GLYCERYL ETHERS.
Topics: Alcohols; Aldehydes; Chromatography; Ethers; Fatty Acids; Folic Acid; Glycerol; Glyceryl Ethers; Liver; Methotrexate; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Pteridines; Pterins; Rats; Research; Stearic Acids | 1964 |
THE ROLE OF CARNITINE IN ACETOACETATE PRODUCTION AND FATTY ACID SYNTHESIS.
Topics: Acetoacetates; Acyltransferases; Amino Alcohols; Animals; Carbon Isotopes; Carnitine; Chromatography; Coenzyme A; Fasting; Fatty Acids; Folic Acid; Guinea Pigs; Lipid Metabolism; Liver; Mitochondria; NAD; Research; Vitamin B Complex | 1965 |
THE INHIBITION OF TWO STEROID-ACTIVATED NICOTINAMIDE-ADENINE DINUCLEOTIDE (PHOSPHATE) TRANSHYDROGENASES BY FOLIC ACID AND FOLIC ACID ANTIMETABOLITES.
Topics: Aminopterin; Androsterone; Antimetabolites; Enzyme Inhibitors; Estradiol; Folic Acid; Hydrogen-Ion Concentration; Methotrexate; NAD; NADP; Oxidoreductases; Pharmacology; Phosphates; Progesterone; Research; Spectrophotometry; Testosterone | 1965 |
THE INHIBITION OF NICOTINAMIDE-ADENINE DINUCLEOTIDE-LINKED 3-ALPHA-HYDROXY STEROID DEHYDROGENASE BY CERTAIN ANTIMETABOLIC DRUGS.
Topics: Aminopterin; Antimetabolites; Diethylstilbestrol; Enzyme Inhibitors; Estradiol; Folic Acid; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Mercaptopurine; Methotrexate; NAD; Oxidoreductases; Research; Steroids; Testosterone; Uracil | 1965 |
Aspartate 120 of Escherichia coli methylenetetrahydrofolate reductase: evidence for major roles in folate binding and catalysis and a minor role in flavin reactivity.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alanine; Asparagine; Aspartic Acid; Catalysis; Cold Temperature; Escherichia coli Proteins; Flavin-Adenine Dinucleotide; Folic Acid; Imines; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Potentiometry; Spectrophotometry; Substrate Specificity; Thermodynamics | 2005 |
Ligand binding modulates the mechanical stability of dihydrofolate reductase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biophysical Phenomena; Biophysics; CHO Cells; Chromatography, Affinity; Cricetinae; Folic Acid; Folic Acid Antagonists; Humans; Ligands; Methotrexate; Microscopy, Atomic Force; NAD; NADP; Niacinamide; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Protein Transport; Spectrophotometry; Stress, Mechanical; Tensile Strength; Tetrahydrofolate Dehydrogenase; Thermodynamics | 2005 |
Structures of NADH and CH3-H4folate complexes of Escherichia coli methylenetetrahydrofolate reductase reveal a spartan strategy for a ping-pong reaction.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; Molecular Sequence Data; NAD; Protein Conformation; Protein Structure, Secondary | 2005 |
Fingerprinting DHFR in single-molecule AFM studies.
Topics: Animals; Biophysical Phenomena; Biophysics; CHO Cells; Chromatography, Affinity; Cricetinae; Cricetulus; Folic Acid; Folic Acid Antagonists; Humans; Ligands; Methotrexate; Microscopy, Atomic Force; NAD; NADP; Niacinamide; Peptide Mapping; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Protein Transport; Spectrophotometry; Stress, Mechanical; Tensile Strength; Tetrahydrofolate Dehydrogenase; Thermodynamics | 2006 |
Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli.
Topics: Amino Acid Substitution; Animals; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Phenylalanine; Protein Binding; Protein Conformation | 2009 |
A novel modified carbon paste electrode based on NiO/CNTs nanocomposite and (9, 10-dihydro-9, 10-ethanoanthracene-11, 12-dicarboximido)-4-ethylbenzene-1, 2-diol as a mediator for simultaneous determination of cysteamine, nicotinamide adenine dinucleotide
Topics: Benzene Derivatives; Biosensing Techniques; Carbon; Cysteamine; Electrochemical Techniques; Electrodes; Folic Acid; Humans; Limit of Detection; NAD; Nanocomposites; Nanotubes, Carbon; Nickel; Pharmaceutical Preparations | 2013 |
Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues.
Topics: Age Factors; Alternative Splicing; Aminohydrolases; Animals; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Isoenzymes; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Mitochondria; Multienzyme Complexes; NAD; NADP; Neural Tube; Oxidation-Reduction; Pregnancy; Rats; Substrate Specificity | 2014 |
A high sensitive electrochemical nanosensor for simultaneous determination of glutathione, NADH and folic acid.
Topics: Electrochemical Techniques; Folic Acid; Glutathione; Limit of Detection; Microscopy, Electron, Transmission; NAD; Nanotechnology; Oxidation-Reduction; Reproducibility of Results | 2015 |
Novel relationships between B12, folate and markers of inflammation, oxidative stress and NAD(H) levels, systemically and in the CNS of a healthy human cohort.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Antioxidants; Biomarkers; Central Nervous System; Deoxyguanosine; F2-Isoprostanes; Female; Folic Acid; Homocysteine; Humans; Inflammation; Interleukin-6; Linear Models; Male; Middle Aged; NAD; Oxidative Stress; Vitamin B 12 | 2015 |
Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.
Topics: Binding Sites; Crystallization; Enzyme Inhibitors; Folic Acid; Humans; Leucovorin; Methenyltetrahydrofolate Cyclohydrolase; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Mitochondria; NAD; Protein Multimerization | 2017 |
Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.
Topics: Cell Line, Tumor; Cell Nucleus; Citric Acid Cycle; DNA Methylation; DNA, Mitochondrial; Epigenesis, Genetic; Folic Acid; HEK293 Cells; Humans; Methionine; Mitochondria; NAD; Osteoblasts; Oxidation-Reduction; Serine; Tricarboxylic Acids | 2018 |
Biochemical and structural characterization of meningococcal methylenetetrahydrofolate reductase.
Topics: Adenine; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; NAD; NADP; Neisseria meningitidis | 2023 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |