Page last updated: 2024-08-17

nad and folic acid

nad has been researched along with folic acid in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199052 (75.36)18.7374
1990's2 (2.90)18.2507
2000's6 (8.70)29.6817
2010's7 (10.14)24.3611
2020's2 (2.90)2.80

Authors

AuthorsStudies
Roberts, GC1
Kaufman, BT; Subramanian, S1
Krumdieck, CL; White, WE; Yielding, LK1
Greenfield, NJ1
James, SJ; Yin, L1
Morrison, JF; Stone, SR1
Kikuchi, G; Yoshida, T1
Frisell, WR; Randolph, VM1
Bhat, JV; Nambudiri, AM1
Gawthorne, JM; Osborne-White, WS; Smith, RM1
Gawthorne, JM; Smith, RM1
Foster, MA; Guest, JR; Woods, DD1
Galloway, E; Kutzbach, C; Stokstad, EL1
Gutteridge, WE; Jaffe, JJ; McCormack, JJ1
Landauer, W; Wakasugi, N1
Kikuchi, G; Motokawa, Y1
Kikuchi, G; Kochi, H; Sato, N; Sato, T1
Daniel, LJ; Griffiths, JM1
Kung, HF; Wagner, C1
Hanna, ML; Taylor, RT1
Ritari, SJ; Rosales, F; Sakami, W1
Herman, RH; Rosensweig, NS; Stifel, FB1
Goodman, JI; Tephly, TR1
Summers, MR1
Kawai, M; Scrimgeour, KG1
Battat, E; Goldberg, I; Mateles, RI1
Bush, ME; Donaldson, KO1
Jaffe, JJ; McCormack, JJ1
Andreeva, NA; Efimova, RI1
Burchall, J1
Kaufman, BT1
Burchall, JJ; Hitchings, GH1
Kikuchi, G; Kochi, H1
Butt, VS; Vaughan, PF1
Leclerc, M1
Bertino, JR; Cashmore, AR; Hillcoat, BL1
Kutzbach, C; Stokstad, EL1
Turner, JM; Willetts, AJ1
Greenfield, NJ; Hirshfield, JM; Hoogsteen, K; Poe, M; Williams, MN1
Drummond, D; MacKenzie, RE; Smith, S1
Collins, TD; McMartin, KE1
Allen, RH; Henderson, LM; Hoyumpa, AM; Middleton, HM; Rose, RC; Rosenberg, IH1
Reynolds, MG; Roos, DS1
Badii, R; Basran, J; Casarotto, MG; Roberts, GC; Sze, KH1
Ballou, DP; Ludwig, ML; Matthews, RG; Trimmer, EE1
OERIU, S1
DEPPE, WM; JOUBERT, SM; MCKECHNIE, JK1
BROWN, GM; REYNOLDS, JJ1
LANGER, BW1
BUCHANAN, JM; ELFORD, HL; LOUGHLIN, RE1
KENNEDY, EP; LINDBERG, M; TIETZ, A1
BRESSLER, R; KATZ, RI1
MAINWARING, WI; WILLIAMS, DC1
LAMBE, RF; WILLIAMS, DC1
Ballou, DP; Brinker, DR; Casas, KR; Galloway, LJ; Scannell, SA; Trimmer, EE1
Ainavarapu, SR; Badilla, CL; Fernandez, JM; Li, L1
Ludwig, ML; Pejchal, R; Sargeant, R1
Ainavarapu, SR; Fernandez, JM; Li, L1
Ballou, DP; Furtado, VC; Lee, MN; Nikolova, AP; Phung, NL; Still, BR; Takawira, D; Tanner, JJ; Thorstad, MK; Trimmer, EE1
Biparva, P; Hatami, M; Karimi-Maleh, H1
Appling, DR; Bryant, JD; Momb, J; Shin, M1
Khalilzadeh, MA; Ojani, R; Raoof, JB; Teymoori, N1
Bilgin, A; Croft, KD; Grant, R; Guest, J; Hokin, B; Mori, TA1
Andersson, Y; Bonagas, N; Dahllund, L; Färnegårdh, K; Gustafsson, NM; Gustafsson, R; Häggblad, M; Helleday, T; Henriksson, M; Homan, E; Jemth, AS; Llona-Minguez, S; Loseva, O; Stenmark, P; Wiita, E1
Bushel, P; Chandel, N; Grenet, D; Li, J; Lozoya, OA; Martinez-Reyes, I; Santos, JH; Wang, T; Woychik, RP1
Heske, CM; Issaq, SH1
Bruning, JB; Jayapalan, JJ; Jovcevski, B; Maenpuen, S; Pantong, W; Pederick, JL; Salaemae, W; Tinikul, R; Wegener, KL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1

Reviews

3 review(s) available for nad and folic acid

ArticleYear
Inhibition of folate biosynthesis and function as a basis for chemotherapy.
    Advances in enzymology and related areas of molecular biology, 1965, Volume: 27

    Topics: Aminobenzoates; Animals; Binding Sites; Biological Transport; Drug Resistance, Microbial; Drug Synergism; Escherichia coli; Folic Acid; Folic Acid Antagonists; Glutamates; Guinea Pigs; Humans; Lactobacillus; Leucovorin; Methotrexate; NAD; NADP; Pteridines; Pyrimidines; Rabbits; Rats; Sulfonamides

1965
BIOGENESIS OF THE WATER-SOLUBLE VITAMINS.
    Annual review of biochemistry, 1963, Volume: 32

    Topics: Alanine; Benzimidazoles; Biotin; Coenzyme A; Flavins; Folic Acid; Hydroxocobalamin; Metabolism; NAD; Niacin; Nicotinic Acids; Nucleosides; Oxidoreductases; Pantothenic Acid; Phosphotransferases; Pterins; Pyridoxine; Research; Riboflavin; Thiamine; Thiamine Pyrophosphate; Vitamin B 12; Vitamins

1963
Targeting metabolic dependencies in pediatric cancer.
    Current opinion in pediatrics, 2020, Volume: 32, Issue:1

    Topics: Amino Acids; Antineoplastic Agents; Child; Folic Acid; Glycolysis; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; NAD; Neoplasms; Oxidative Phosphorylation; Polyamines

2020

Other Studies

66 other study(ies) available for nad and folic acid

ArticleYear
The binding of substrates and inhibitors to dihydrofolate reductase.
    Biochemical Society transactions, 1975, Volume: 3, Issue:5

    Topics: Binding Sites; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Kinetics; Ligands; NAD; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase

1975
Interaction of methotrexate, folates, and pyridine nucleotides with dihydrofolate reductase: calorimetric and spectroscopic binding studies.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:7

    Topics: Animals; Calorimetry; Chickens; Folic Acid; Liver; Methotrexate; NAD; NADP; Protein Binding; Protons; Spectrum Analysis; Tetrahydrofolate Dehydrogenase; Thermodynamics

1978
Folates as inhibitors of glutamate dehydrogenase.
    Biochimica et biophysica acta, 1976, May-13, Volume: 429, Issue:3

    Topics: Aminobenzoates; Animals; Binding Sites; Cattle; Folic Acid; Glutamate Dehydrogenase; Glutamates; Kinetics; Liver; Methotrexate; NAD; Peptides; Pterins; Tetrahydrofolates

1976
Circular dichroism studies of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli B, MB 1428: ternary complexes.
    Biochimica et biophysica acta, 1975, Sep-22, Volume: 403, Issue:1

    Topics: Adenosine Diphosphate Sugars; Binding Sites; Circular Dichroism; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Methotrexate; NAD; NADP; Nicotinamide Mononucleotide; Protein Binding; Protein Conformation; Ribose; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase

1975
Diet-induced DNA damage and altered nucleotide metabolism in lymphocytes from methyl-donor-deficient rats.
    Carcinogenesis, 1989, Volume: 10, Issue:7

    Topics: Animals; Choline; Choline Deficiency; Deoxyuridine; Diet; DNA Damage; DNA Replication; Folic Acid; Folic Acid Deficiency; Liver; Lymphocytes; Male; Methionine; NAD; Nucleotides; Rats; Rats, Inbred F344; Reference Values; RNA; Spleen; Thymidine

1989
Dihydrofolate reductase from Escherichia coli: the kinetic mechanism with NADPH and reduced acetylpyridine adenine dinucleotide phosphate as substrates.
    Biochemistry, 1988, Jul-26, Volume: 27, Issue:15

    Topics: Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Tetrahydrofolate Dehydrogenase; Viscosity

1988
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
    Archives of biochemistry and biophysics, 1971, Volume: 145, Issue:2

    Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid

1971
Effect of adenine nucleotides on the oxidation of methyl groups in liver mitochondria.
    Biochimica et biophysica acta, 1973, Feb-22, Volume: 292, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Carbon Dioxide; Dinitrophenols; Folic Acid; Formaldehyde; Formates; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylation; Mitochondria, Liver; Mitochondrial Swelling; NAD; NADP; Oxygen Consumption; Rats; Rotenone; Sarcosine; Semicarbazides; Serine

1973
Conversion of p-coumarate into caffeate by Streptomyces nigrifaciens. Purification and properties of the hydroxylating enzyme.
    The Biochemical journal, 1972, Volume: 130, Issue:2

    Topics: Ascorbic Acid; Chromatography, Gel; Cinnamates; Copper; Coumarins; Electrophoresis, Polyacrylamide Gel; Folic Acid; Hydroxylation; Mixed Function Oxygenases; Molecular Weight; NAD; NADP; Oxidoreductases; Phenols; Streptomyces

1972
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on liver constituents associated with folate metabolism.
    The Biochemical journal, 1974, Volume: 142, Issue:1

    Topics: Adenosine Triphosphate; Animals; Azo Compounds; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Enterococcus faecalis; Female; FIGLU Test; Folic Acid; Glutarates; Lacticaseibacillus casei; Liver; Methionine; NAD; NADP; Pediococcus; Potassium; Sheep; Sodium; Tetrahydrofolates; Vitamin B 12 Deficiency

1974
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on methotrexate transport and the activity of enzymes associated with folate metabolism in liver.
    The Biochemical journal, 1974, Volume: 142, Issue:1

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Female; Folic Acid; Homocysteine; Liver; Membranes; Methionine; Methotrexate; Methyltransferases; NAD; NADP; S-Adenosylmethionine; Serum Albumin, Bovine; Sheep; Tetrahydrofolate Dehydrogenase; Tritium; Vitamin B 12; Vitamin B 12 Deficiency

1974
Methyl derivatives of folic acid as intermediates in the methylation of homocysteine by Escherichia coli.
    The Biochemical journal, 1964, Volume: 92, Issue:3

    Topics: Alkylation; Chromatography; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; In Vitro Techniques; Methionine; Molecular Biology; Mutation; NAD

1964
Influence of vitamin B12 and methionine on levels of folic acid compounds and folate enzymes in rat liver.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:3

    Topics: Animals; Biological Assay; Female; Folic Acid; Liver; Methionine; NAD; Oxidoreductases; Pregnancy; Pregnancy, Animal; Rats; Transferases; Vitamin B 12

1967
Presence and properties of dihydrofolate reductases within the genus Trypanosoma.
    British journal of pharmacology, 1968, Volume: 34, Issue:1

    Topics: Aminopterin; Animals; Depression, Chemical; Folic Acid; Methotrexate; NAD; Tetrahydrofolate Dehydrogenase; Trypanosoma

1968
Teratological studies with sulphonamides and their implications.
    Journal of embryology and experimental morphology, 1968, Volume: 20, Issue:3

    Topics: Abnormalities, Drug-Induced; Adenine Nucleotides; Animals; Carbonic Anhydrase Inhibitors; Chick Embryo; Chloramines; Dichlorphenamide; Drug Synergism; Folic Acid; Methazolamide; NAD; Pyridines; Sulfanilamides; Sulfonamides; Time Factors

1968
Glycine metabolism by rat liver mitochondria. II. Methylene tetrahydrofolate as the direct on carbon donor in the reaction of glycine synthesis.
    Journal of biochemistry, 1969, Volume: 65, Issue:1

    Topics: Animals; Arsenic; Carbon; Carbon Isotopes; Folic Acid; Glycine; In Vitro Techniques; Mitochondria, Liver; NAD; Pyridoxal Phosphate; Rats; Sulfhydryl Compounds; Time Factors; Transferases

1969
Glycine metabolism by rat liver mitochondria. 3. The glycine cleavage and the exchange of carboxyl carbon of glycine with bicarbonate.
    Journal of biochemistry, 1969, Volume: 65, Issue:1

    Topics: Ammonia; Animals; Arsenic; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Folic Acid; Glycine; In Vitro Techniques; Kinetics; Mitochondria, Liver; NAD; Pyridoxal Phosphate; Rats; Serine; Sulfhydryl Compounds; Transferases

1969
Methionine biosynthesis in Ochromonas malhamensis.
    Archives of biochemistry and biophysics, 1969, Volume: 134, Issue:2

    Topics: Adenosine Triphosphate; Alcohols; Carbon Isotopes; Cyanides; Enzyme Activation; Eukaryota; Flavin Mononucleotide; Folic Acid; Homocysteine; Kinetics; Light; Magnesium; Methionine; NAD; Oxygen; Sulfur; Transferases; Vitamin B 12

1969
The enzymatic synthesis of N-methylalanine.
    Biochimica et biophysica acta, 1970, Mar-24, Volume: 201, Issue:3

    Topics: Adenosine Triphosphate; Alanine; Amines; Autoradiography; Carbon Isotopes; Chromatography, Gel; Chromatography, Thin Layer; Crystallization; Electrophoresis; Folic Acid; Glutamates; Magnesium; NAD; Paper; Pseudomonas; Pyruvates; Serine

1970
Escherichia coli B cobalamin methyltransferase: ability of diaphorases and lipoamide dehydrogenases to function as reducing agents.
    Archives of biochemistry and biophysics, 1970, Volume: 139, Issue:1

    Topics: Alcohols; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Dihydrolipoamide Dehydrogenase; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Iodoacetates; Methionine; Methylation; Myocardium; NAD; Spectrophotometry; Sulfhydryl Compounds; Swine; Transferases; Vitamin B 12

1970
Formation of the N5-methyltetrahydrofolate-homocysteine methyltransferase holoenzyme from apoenzyme and adenosyl-B 12.
    Biochemical and biophysical research communications, 1970, Jul-27, Volume: 40, Issue:2

    Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Enzyme Precursors; Escherichia coli; Folic Acid; Homocysteine; Methionine; NAD; Transferases; Vitamin B 12

1970
Dietary regulation of glycolytic enzymes. XI. Effect of inhibitors of protein synthesis on the adaptation of certain jejunal glycolytic and folate-metabolizing enzymes to diet and sex steroids.
    Biochimica et biophysica acta, 1971, Jun-22, Volume: 237, Issue:3

    Topics: Aldehyde-Lyases; Animals; Caseins; Dactinomycin; Dietary Carbohydrates; Dietary Proteins; Enzyme Induction; Estradiol; Ethionine; Fasting; Female; Folic Acid; Fructose; Fructosephosphates; Glycolysis; Jejunum; Male; Metabolism; NAD; Oxidoreductases; Pyruvate Kinase; Rats; RNA; Serine; Testosterone; Time Factors; Transferases

1971
A comparison of rat and human liver formaldehyde dehydrogenase.
    Biochimica et biophysica acta, 1971, Dec-21, Volume: 252, Issue:3

    Topics: Alcohol Oxidoreductases; Aldehydes; Animals; Calcium Phosphates; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Enzyme Activation; Female; Folic Acid; Formaldehyde; Gels; Glutathione; Humans; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Liver; Macromolecular Substances; Male; Molecular Weight; NAD; Oxidoreductases; Phenanthrolines; Rats

1971
Reaction of N-bromosuccinimide with reduced ring systems. Apparent protection of glutamate dehydrogenase by reduced nicotinamide-adenine dinucleotide.
    Biochemistry, 1972, Aug-01, Volume: 11, Issue:16

    Topics: Bromine; Chemical Phenomena; Chemistry; Folic Acid; Glutamate Dehydrogenase; NAD; Oxidation-Reduction; Pteridines; Pyrrolidinones; Spectrophotometry; Succinimides; Ultraviolet Rays

1972
Reduction of folate and dihydrofolate by dithionite.
    Canadian journal of biochemistry, 1972, Volume: 50, Issue:11

    Topics: Chemical Phenomena; Chemistry; Folic Acid; Hydrogen-Ion Concentration; Kinetics; NAD; Nitrophenols; Osmolar Concentration; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Sulfites; Temperature

1972
Megavitamin and orthomolecular therapy in psychiatry.
    Nutrition reviews, 1974, Volume: 32, Issue:0

    Topics: Aged; Alcoholism; Ascorbic Acid; Avitaminosis; Child; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Folic Acid; Humans; Mental Disorders; NAD; Nicotinic Acids; Psychiatry; Pyridoxine; Schizophrenia; Substance-Related Disorders; Vitamin B 12; Vitamins

1974
Growth of Pseudomonas C on C1 compounds: continuoous culture.
    Applied microbiology, 1974, Volume: 28, Issue:6

    Topics: Aminobenzoates; Carbon Dioxide; Carbon Radioisotopes; Folic Acid; Formaldehyde; Formates; Glycine; Methanol; NAD; Polysorbates; Pseudomonas; Serine

1974
Tetrahydrofolate dehydrogenase from bakers' yeast.
    Biochemical and biophysical research communications, 1965, Sep-08, Volume: 20, Issue:5

    Topics: Chromatography; Folic Acid; In Vitro Techniques; Mercaptoethanol; NAD; NADP; Saccharomyces; Spectrophotometry; Tetrahydrofolate Dehydrogenase

1965
Dihydrofolate reductase from Trypanosoma equiperdum. I. Isolation, partial purification, and properties.
    Molecular pharmacology, 1967, Volume: 3, Issue:4

    Topics: Aminopterin; Animals; Folic Acid; Folic Acid Antagonists; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Methotrexate; NAD; NADP; Pyrimethamine; Rats; Tetrahydrofolate Dehydrogenase; Trypanosoma

1967
[An aminopterine-resistant enzymatic way of reduction of folic acid to a coenzymic form, discovered in plants].
    Doklady Akademii nauk SSSR, 1966, Apr-01, Volume: 167, Issue:4

    Topics: Aminopterin; Chromatography; Chromatography, Gel; Coenzymes; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; NAD; NADP; Plants

1966
Protection of microbial dihydrofolate reductase against inactivation by pronase.
    Molecular pharmacology, 1968, Volume: 4, Issue:3

    Topics: Amines; Benzoates; Calcium; Chromatography; Endopeptidases; Escherichia coli; Folic Acid; Folic Acid Antagonists; Formates; Glutamates; Heterocyclic Compounds; Kinetics; Leucovorin; NAD; NADP; Protein Binding; Pteridines

1968
Studies on dihydrofolic reductase. 3. Activation of the chicken liver enzyme by urea and thiourea.
    The Journal of biological chemistry, 1968, Nov-25, Volume: 243, Issue:22

    Topics: Animals; Chickens; Folic Acid; Formamides; Glycerol; Guanidines; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; NADP; Optical Rotatory Dispersion; Protein Binding; Tetrahydrofolate Dehydrogenase; Thiourea; Urea

1968
Reactions of glycine synthesis and glycine cleavage catalyzed by extracts of Arthrobacter globiformis grown on glycine.
    Archives of biochemistry and biophysics, 1969, Volume: 132, Issue:2

    Topics: Ammonium Chloride; Arthrobacter; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Folic Acid; Formaldehyde; Glutathione; Glycine; Ion Exchange Resins; Kinetics; Mitochondria, Liver; NAD; NADP; Pyridoxal Phosphate; Serine; Sulfhydryl Compounds

1969
The hydroxylation of p-coumaric acid by an enzyme from leaves of spinach beet (Beta vulgaris L.).
    The Biochemical journal, 1969, Volume: 113, Issue:1

    Topics: Ascorbic Acid; Catechol Oxidase; Coumarins; Folic Acid; Mixed Function Oxygenases; NAD; NADP; Plants; Pteridines

1969
[Coenzymes (vitamins)].
    L' Alimentation et la vie, 1970, Volume: 58, Issue:1

    Topics: Ascorbic Acid; Biotin; Chemical Phenomena; Chemistry; Coenzyme A; Coenzymes; Cytochromes; Flavin-Adenine Dinucleotide; Folic Acid; Glutathione; NAD; NADP; Nucleosides; Pyridoxine; Thiamine; Thioctic Acid; Ubiquinone; Vitamins

1970
"Induction" of dihydrofolate reductase: purification and properties of the "induced" human erythrocyte and leukocyte enzyme and normal bone marrow enzyme.
    Cancer research, 1970, Volume: 30, Issue:9

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromatography; Enzyme Activation; Enzyme Induction; Erythrocytes; Folic Acid; Humans; Hydrogen-Ion Concentration; Immune Sera; Leukemia L1210; Leukocytes; Methotrexate; Molecular Weight; NAD; NADP; Neoplasms; Protein Denaturation; Tetrahydrofolate Dehydrogenase

1970
Mammalian methylenetetrahydrofolate reductase. Partial purification, properties, and inhibition by S-adenosylmethionine.
    Biochimica et biophysica acta, 1971, Dec-15, Volume: 250, Issue:3

    Topics: Adenosine; Alcohol Oxidoreductases; Ammonium Sulfate; Animals; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Drug Stability; Flavin-Adenine Dinucleotide; Folic Acid; Formaldehyde; Homocysteine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; NADP; Rats; S-Adenosylmethionine; Spectrophotometry; Swine; Vitamin K

1971
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
    Biochimica et biophysica acta, 1971, Volume: 252, Issue:1

    Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases

1971
Dihydrofolate reductase. Purification and characterization of the enzyme from an amethopterin-resistant mutant of Escherichia coli.
    Biochemistry, 1972, Mar-14, Volume: 11, Issue:6

    Topics: Amino Acids; Chromatography, Affinity; Chromatography, Gel; Cyanogen Bromide; Dansyl Compounds; Drug Resistance, Microbial; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Methotrexate; NAD; NADP; Osmolar Concentration; Potassium Chloride; Sodium Chloride; Tetrahydrofolate Dehydrogenase; Ultracentrifugation

1972
Methylenetetrahydrofolate dehydrogenase - methenyltetrahydrofolate cyclohydrolase - formyltetrahydrofolate synthetase from porcine liver: evidence to support a common dehydrogenase-cyclohydrolase site.
    Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 1983, Volume: 61, Issue:11

    Topics: Aminohydrolases; Animals; Binding Sites; Diethyl Pyrocarbonate; Folic Acid; Formate-Tetrahydrofolate Ligase; Kinetics; Ligases; Liver; Methenyltetrahydrofolate Cyclohydrolase; Methylenetetrahydrofolate Dehydrogenase (NADP); Multienzyme Complexes; NAD; NADP; Oxidoreductases; Phenylglyoxal; Swine

1983
Relationship of alcohol metabolism to folate deficiency produced by ethanol in the rat.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18 Suppl 1

    Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Folic Acid; Folic Acid Deficiency; Male; Metabolic Clearance Rate; Methanol; NAD; Rats; Rats, Inbred Strains

1983
Transport and metabolism of water-soluble vitamins in intestine and kidney.
    Federation proceedings, 1984, Volume: 43, Issue:9

    Topics: Animals; Ascorbic Acid; Biological Transport; Coenzyme A; Digestion; Folic Acid; Humans; Intestinal Absorption; Intestinal Mucosa; Kidney; Microvilli; NAD; Pyridoxine; Thiamine; Vitamin B 12; Vitamins

1984
A biochemical and genetic model for parasite resistance to antifolates. Toxoplasma gondii provides insights into pyrimethamine and cycloguanil resistance in Plasmodium falciparum.
    The Journal of biological chemistry, 1998, Feb-06, Volume: 273, Issue:6

    Topics: Alleles; Animals; Binding Sites; Drug Resistance; Escherichia coli; Folic Acid; Folic Acid Antagonists; Genetic Complementation Test; Kinetics; Models, Genetic; Models, Molecular; Mutagenesis, Site-Directed; NAD; Plasmodium falciparum; Proguanil; Pyrimethamine; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Toxoplasma; Triazines

1998
Direct measurement of the pKa of aspartic acid 26 in Lactobacillus casei dihydrofolate reductase: implications for the catalytic mechanism.
    Biochemistry, 1999, Jun-22, Volume: 38, Issue:25

    Topics: Apoenzymes; Aspartic Acid; Catalysis; Folic Acid; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Macromolecular Substances; NAD; Tetrahydrofolate Dehydrogenase

1999
Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
    Biochemistry, 2001, May-29, Volume: 40, Issue:21

    Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Enzyme Activation; Escherichia coli; Folic Acid; Glutamic Acid; Glutamine; Kinetics; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Spectrophotometry; Vitamin K

2001
[Research on the relation between vitamin coenzymes and corresponding enzymes in relation to the age of the animal and under the influence of certain substances proper to the organism].
    Biokhimiia (Moscow, Russia), 1963, Volume: 28

    Topics: Acetylesterase; Adenine Nucleotides; Aging; Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Coenzymes; Cysteine; D-Alanine Transaminase; Folic Acid; Humans; NAD; Niacin; Niacinamide; Pantothenic Acid; Pyridoxine; Riboflavin; Thiamine; Thiamine Pyrophosphate; Vitamins

1963
SOME ASPECTS OF INTERMEDIARY METABOLISM IN AFRICAN (BANTU) PORPHYRIA (PORPHYRIA CUTANEA TARDA SYMPTOMATICA).
    South African journal of laboratory and clinical medicine. Suid-Afrikaanse tydskrif vir laboratorium- en kliniekwerk, 1963, Volume: 14

    Topics: Black People; Blood; Citrates; Citric Acid Cycle; Folic Acid; Humans; Ketoglutaric Acids; Metabolism; NAD; Porphyria Cutanea Tarda; Porphyrias; Pyruvates; South Africa; Vitamin B Complex

1963
ORGAN AND INTRACELLULAR LOCATION OF THE METHIONINE METHYL GROUP SYNTHESIZING SYSTEM OF THE RAT.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: Adenosine Triphosphate; Brain; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Glucose; Homocysteine; Kidney; Leuconostoc; Liver; Magnesium; Methionine; Muscles; NAD; Pectoralis Muscles; Proteins; Pyridoxal Phosphate; Rats; Research; Serine; Spectrophotometry

1964
ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. VII. ISOLATION OF A COBALAMIN-CONTAINING TRANSMETHYLASE (5-METHYLTETRAHYDRO-FOLATE-HOMOCYSTEINE) FROM MAMMALIAN LIVER.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Animals; Chromatography; Corrinoids; Flavin-Adenine Dinucleotide; Folic Acid; Glutamates; Homocysteine; Liver; Methionine; Methyltransferases; NAD; NADP; Protamines; Research; Swine; Transferases; Vitamin B 12

1964
A NEW PTERIDINE-REQUIRING ENZYME SYSTEM FOR THE OXIDATION OF GLYCERYL ETHERS.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Alcohols; Aldehydes; Chromatography; Ethers; Fatty Acids; Folic Acid; Glycerol; Glyceryl Ethers; Liver; Methotrexate; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Pteridines; Pterins; Rats; Research; Stearic Acids

1964
THE ROLE OF CARNITINE IN ACETOACETATE PRODUCTION AND FATTY ACID SYNTHESIS.
    The Journal of clinical investigation, 1965, Volume: 44

    Topics: Acetoacetates; Acyltransferases; Amino Alcohols; Animals; Carbon Isotopes; Carnitine; Chromatography; Coenzyme A; Fasting; Fatty Acids; Folic Acid; Guinea Pigs; Lipid Metabolism; Liver; Mitochondria; NAD; Research; Vitamin B Complex

1965
THE INHIBITION OF TWO STEROID-ACTIVATED NICOTINAMIDE-ADENINE DINUCLEOTIDE (PHOSPHATE) TRANSHYDROGENASES BY FOLIC ACID AND FOLIC ACID ANTIMETABOLITES.
    The Biochemical journal, 1965, Volume: 94

    Topics: Aminopterin; Androsterone; Antimetabolites; Enzyme Inhibitors; Estradiol; Folic Acid; Hydrogen-Ion Concentration; Methotrexate; NAD; NADP; Oxidoreductases; Pharmacology; Phosphates; Progesterone; Research; Spectrophotometry; Testosterone

1965
THE INHIBITION OF NICOTINAMIDE-ADENINE DINUCLEOTIDE-LINKED 3-ALPHA-HYDROXY STEROID DEHYDROGENASE BY CERTAIN ANTIMETABOLIC DRUGS.
    The Biochemical journal, 1965, Volume: 95

    Topics: Aminopterin; Antimetabolites; Diethylstilbestrol; Enzyme Inhibitors; Estradiol; Folic Acid; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Mercaptopurine; Methotrexate; NAD; Oxidoreductases; Research; Steroids; Testosterone; Uracil

1965
Aspartate 120 of Escherichia coli methylenetetrahydrofolate reductase: evidence for major roles in folate binding and catalysis and a minor role in flavin reactivity.
    Biochemistry, 2005, May-10, Volume: 44, Issue:18

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alanine; Asparagine; Aspartic Acid; Catalysis; Cold Temperature; Escherichia coli Proteins; Flavin-Adenine Dinucleotide; Folic Acid; Imines; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Potentiometry; Spectrophotometry; Substrate Specificity; Thermodynamics

2005
Ligand binding modulates the mechanical stability of dihydrofolate reductase.
    Biophysical journal, 2005, Volume: 89, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biophysical Phenomena; Biophysics; CHO Cells; Chromatography, Affinity; Cricetinae; Folic Acid; Folic Acid Antagonists; Humans; Ligands; Methotrexate; Microscopy, Atomic Force; NAD; NADP; Niacinamide; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Protein Transport; Spectrophotometry; Stress, Mechanical; Tensile Strength; Tetrahydrofolate Dehydrogenase; Thermodynamics

2005
Structures of NADH and CH3-H4folate complexes of Escherichia coli methylenetetrahydrofolate reductase reveal a spartan strategy for a ping-pong reaction.
    Biochemistry, 2005, Aug-30, Volume: 44, Issue:34

    Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; Molecular Sequence Data; NAD; Protein Conformation; Protein Structure, Secondary

2005
Fingerprinting DHFR in single-molecule AFM studies.
    Biophysical journal, 2006, Sep-01, Volume: 91, Issue:5

    Topics: Animals; Biophysical Phenomena; Biophysics; CHO Cells; Chromatography, Affinity; Cricetinae; Cricetulus; Folic Acid; Folic Acid Antagonists; Humans; Ligands; Methotrexate; Microscopy, Atomic Force; NAD; NADP; Niacinamide; Peptide Mapping; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Protein Transport; Spectrophotometry; Stress, Mechanical; Tensile Strength; Tetrahydrofolate Dehydrogenase; Thermodynamics

2006
Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli.
    Biochemistry, 2009, Aug-18, Volume: 48, Issue:32

    Topics: Amino Acid Substitution; Animals; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Phenylalanine; Protein Binding; Protein Conformation

2009
A novel modified carbon paste electrode based on NiO/CNTs nanocomposite and (9, 10-dihydro-9, 10-ethanoanthracene-11, 12-dicarboximido)-4-ethylbenzene-1, 2-diol as a mediator for simultaneous determination of cysteamine, nicotinamide adenine dinucleotide
    Biosensors & bioelectronics, 2013, Oct-15, Volume: 48

    Topics: Benzene Derivatives; Biosensing Techniques; Carbon; Cysteamine; Electrochemical Techniques; Electrodes; Folic Acid; Humans; Limit of Detection; NAD; Nanocomposites; Nanotubes, Carbon; Nickel; Pharmaceutical Preparations

2013
Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues.
    The Journal of biological chemistry, 2014, May-30, Volume: 289, Issue:22

    Topics: Age Factors; Alternative Splicing; Aminohydrolases; Animals; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Isoenzymes; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Mitochondria; Multienzyme Complexes; NAD; NADP; Neural Tube; Oxidation-Reduction; Pregnancy; Rats; Substrate Specificity

2014
A high sensitive electrochemical nanosensor for simultaneous determination of glutathione, NADH and folic acid.
    Materials science & engineering. C, Materials for biological applications, 2015, Volume: 47

    Topics: Electrochemical Techniques; Folic Acid; Glutathione; Limit of Detection; Microscopy, Electron, Transmission; NAD; Nanotechnology; Oxidation-Reduction; Reproducibility of Results

2015
Novel relationships between B12, folate and markers of inflammation, oxidative stress and NAD(H) levels, systemically and in the CNS of a healthy human cohort.
    Nutritional neuroscience, 2015, Volume: 18, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Antioxidants; Biomarkers; Central Nervous System; Deoxyguanosine; F2-Isoprostanes; Female; Folic Acid; Homocysteine; Humans; Inflammation; Interleukin-6; Linear Models; Male; Middle Aged; NAD; Oxidative Stress; Vitamin B 12

2015
Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.
    Cancer research, 2017, 02-15, Volume: 77, Issue:4

    Topics: Binding Sites; Crystallization; Enzyme Inhibitors; Folic Acid; Humans; Leucovorin; Methenyltetrahydrofolate Cyclohydrolase; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Mitochondria; NAD; Protein Multimerization

2017
Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.
    PLoS biology, 2018, Volume: 16, Issue:4

    Topics: Cell Line, Tumor; Cell Nucleus; Citric Acid Cycle; DNA Methylation; DNA, Mitochondrial; Epigenesis, Genetic; Folic Acid; HEK293 Cells; Humans; Methionine; Mitochondria; NAD; Osteoblasts; Oxidation-Reduction; Serine; Tricarboxylic Acids

2018
Biochemical and structural characterization of meningococcal methylenetetrahydrofolate reductase.
    Protein science : a publication of the Protein Society, 2023, Volume: 32, Issue:6

    Topics: Adenine; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; NAD; NADP; Neisseria meningitidis

2023
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010