Compounds > nad
Page last updated: 2024-08-17

nad and dichloroacetic acid

nad has been researched along with dichloroacetic acid in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's4 (28.57)18.2507
2000's2 (14.29)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeBuysere, MS; Dennis, SC; Olson, MS; Padmas, A1
Illingworth, JA; Mullings, R; Strong, P1
Bastianelli, P; Cannelli, B; Cingolani, ML; Salvucci, MP1
Barton, HA; Brashear, WT; Lipscomb, JC; Mahle, DA1
Bolling, SF; Childs, KF; Olszanski, D; Wahr, JA1
Constantin-Teodosiu, D; Greenhaff, PL; Macdonald, IA; Poucher, SM; Timmons, JA1
Bowker-Kinley, MM; Davis, WI; Harris, RA; Popov, KM; Wu, P1
Baker, JC; Kasten, S; Peng, T; Roche, TE; Yan, X1
Balaban, RS; Combs, CA1
Andrejeva, G; Boult, JK; Chung, YL; Eykyn, TR; Fong, AC; Griffiths, JR; Hill, DK; Jafar, M; Judson, IR; Koh, DM; Leach, MO; Lin, G; Orton, MR; Panek, R; Parkes, HG; Robinson, SP; Troy, H1
Agriesti, F; Capitanio, N; Laurenzana, I; Lo Muzio, L; Mazzoccoli, C; Perrone, D; Piccoli, C; Ruggieri, V; Scrima, R; Tataranni, T1
Brooks, DM; Jaimes, R; Kay, MW; Kuzmiak-Glancy, S; Posnack, NG; Swift, LM1
Asta, J; Azam, MA; Farid, T; Jaimes, R; Kay, MW; Kusha, M; Kuzmiak-Glancy, S; Lai, PF; Lopaschuk, GD; Massé, S; Nanthakumar, K; Wagg, CS1
Stacpoole, PW1

Reviews

1 review(s) available for nad and dichloroacetic acid

ArticleYear
Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.
    Journal of the National Cancer Institute, 2017, 11-01, Volume: 109, Issue:11

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Biomimetics; Citric Acid Cycle; Dichloroacetic Acid; Energy Metabolism; Glycolysis; Humans; Isoenzymes; Mitochondria; NAD; Neoplasms; Oxidative Phosphorylation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid

2017

Other Studies

13 other study(ies) available for nad and dichloroacetic acid

ArticleYear
Studies on the regulation of pyruvate dehydrogenase in the isolated perfused rat heart.
    The Journal of biological chemistry, 1979, Feb-25, Volume: 254, Issue:4

    Topics: Acetyl Coenzyme A; Adenine Nucleotides; Animals; Coenzyme A; Dichloroacetic Acid; In Vitro Techniques; Kinetics; Male; Myocardium; NAD; Oxidation-Reduction; Perfusion; Pyruvate Dehydrogenase Complex; Pyruvates; Rats

1979
Aerobic lactate synthesis by cardiac muscle.
    European journal of biochemistry, 1979, Dec-17, Volume: 102, Issue:2

    Topics: Aerobiosis; Aminooxyacetic Acid; Animals; Caprylates; Dichloroacetic Acid; Heart; Kinetics; Lactates; Male; Myocardium; NAD; Perfusion; Pyruvate Dehydrogenase Complex; Pyruvates; Rats

1979
[Redox and phosphorylation equilibrium of the central metabolic pathway: rat liver profile in controls and after treatment with dichloroacetate and phenformin following dichloroacetate].
    Bollettino della Societa italiana di biologia sperimentale, 1980, May-30, Volume: 56, Issue:10

    Topics: Acetates; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Dichloroacetic Acid; Liver; Male; Mitochondria, Liver; NAD; NADP; Phenformin; Phosphates; Rats

1980
Dichloroacetic acid: metabolism in cytosol.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:11

    Topics: Animals; Atmospheric Pressure; Chromatography, Affinity; Cytochrome P-450 Enzyme System; Cytosol; Dichloroacetic Acid; Glutathione; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; NAD; Rats; Rats, Inbred F344; Subcellular Fractions; Tissue Distribution

1995
Dichloroacetate enhanced myocardial functional recovery post-ischemia : ATP and NADH recovery.
    The Journal of surgical research, 1996, Volume: 63, Issue:1

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Blood Pressure; Coronary Circulation; Dichloroacetic Acid; Energy Metabolism; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; NAD; Oxidation-Reduction; Oxygen Consumption; Rabbits; Time Factors

1996
Metabolic responses from rest to steady state determine contractile function in ischemic skeletal muscle.
    The American journal of physiology, 1997, Volume: 273, Issue:2 Pt 1

    Topics: Acetylcarnitine; Animals; Dichloroacetic Acid; Dogs; Homeostasis; In Vitro Techniques; Ischemia; Muscle Contraction; Muscle, Skeletal; NAD; Phosphocreatine; Regional Blood Flow; Rest; Time Factors

1997
Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex.
    The Biochemical journal, 1998, Jan-01, Volume: 329 ( Pt 1)

    Topics: Acetyl Coenzyme A; Animals; Blotting, Northern; Cloning, Molecular; Dichloroacetic Acid; Gene Expression Regulation, Enzymologic; Isoenzymes; Kinetics; Molecular Sequence Data; NAD; Pyruvate Dehydrogenase Complex; Rats; Recombinant Proteins; RNA, Messenger; Sequence Analysis, DNA

1998
Marked differences between two isoforms of human pyruvate dehydrogenase kinase.
    The Journal of biological chemistry, 2000, May-26, Volume: 275, Issue:21

    Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Binding Sites; Buffers; Dichloroacetic Acid; Dihydrolipoyllysine-Residue Acetyltransferase; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; NAD; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Recombinant Proteins

2000
Direct imaging of dehydrogenase activity within living cells using enzyme-dependent fluorescence recovery after photobleaching (ED-FRAP).
    Biophysical journal, 2001, Volume: 80, Issue:4

    Topics: Animals; Cyclic AMP; Dichloroacetic Acid; Flavin-Adenine Dinucleotide; Glutamate Dehydrogenase; Image Processing, Computer-Assisted; Microscopy, Confocal; Mitochondria; Models, Chemical; Myocardium; NAD; Oxidoreductases; Perfusion; Rabbits; Spectrometry, Fluorescence; Temperature; Time Factors

2001
Dichloroacetate induces autophagy in colorectal cancer cells and tumours.
    British journal of cancer, 2014, Jul-15, Volume: 111, Issue:2

    Topics: Animals; Apoptosis; Autophagy; Cell Cycle Checkpoints; Cell Line, Tumor; Colorectal Neoplasms; Dichloroacetic Acid; Female; HCT116 Cells; HT29 Cells; Humans; Lactic Acid; Mice; Mice, Nude; Microscopy, Electron; NAD; Random Allocation; Reactive Oxygen Species; TNF-Related Apoptosis-Inducing Ligand; TOR Serine-Threonine Kinases

2014
Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment.
    Oncotarget, 2015, Jan-20, Volume: 6, Issue:2

    Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Glycolysis; Humans; Immunoblotting; Membrane Potential, Mitochondrial; Mitochondria; Mouth Neoplasms; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Phosphorylation; Pyruvate Dehydrogenase (Lipoamide)

2015
Functional response of the isolated, perfused normoxic heart to pyruvate dehydrogenase activation by dichloroacetate and pyruvate.
    Pflugers Archiv : European journal of physiology, 2016, Volume: 468, Issue:1

    Topics: Animals; Calcium; Dichloroacetic Acid; Glucose; Heart; Isolated Heart Preparation; Myocardial Contraction; Myocardium; NAD; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ventricular Function

2016
Feeding the fibrillating heart: Dichloroacetate improves cardiac contractile dysfunction following VF.
    American journal of physiology. Heart and circulatory physiology, 2015, Volume: 309, Issue:9

    Topics: Animals; Dichloroacetic Acid; Heart; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; NAD; Phosphorylation; Pressure; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Left; Ventricular Fibrillation; Ventricular Function, Left

2015