Page last updated: 2024-08-17

nad and cyclic adp-ribose

nad has been researched along with cyclic adp-ribose in 135 studies

Research

Studies (135)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (0.74)	18.7374
1990's	54 (40.00)	18.2507
2000's	49 (36.30)	29.6817
2010's	21 (15.56)	24.3611
2020's	10 (7.41)	2.80

Authors

Authors	Studies
Aarhus, R; Lee, HC	2
Koshiyama, H; Lee, HC; Tashjian, AH	1
Bratt, GT; Clapper, DL; Hayes, RN; Lee, HC; Walseth, TF	1
Kuemmerle, JF; Makhlouf, GM	1
Galione, A; Potter, BV; Turner, M; Watson, SP; White, A; Willmott, N	1
Brown, DA; Egorova, A; Higashida, H; Ishizaka, N; Noda, M; Okamoto, H; Robbins, J; Takasawa, S; Taketo, M	1
Mészáros, LG; Mészáros, V; Socci, R	1
Sitsapesan, R; Williams, AJ	1
Campana, D; Coustan-Smith, E; Evans, WE; Kumagai, M; Malavasi, F; Murray, DJ; Murti, KG; Silvennoinen, O	1
Lee, HC	2
Beers, KW; Chini, EN; Dousa, TP; Lee, HC	1
Fruen, BR; Louis, CF; Mickelson, JR; Shomer, NH; Velez, P	1
Muller-Steffner, H; Muzard, M; Oppenheimer, N; Schuber, F	1
Bazan, JF; Grimaldi, JC; Howard, M; Lee, HC; Lund, FE; Parkhouse, RM; Santos-Argumedo, L; Walseth, TF	1
Galione, A; Jackson, DG; Summerhill, RJ	1
Culver, GM; Kierzek, R; LaReau, RD; McCraith, SM; Michaud, N; Phizicky, EM; Turner, DH; Zillmann, M	1
Jacobson, EL; Jacobson, MK; Kim, H	1
Benatti, U; De Flora, A; Franco, L; Guida, L; Lee, HC; Zocchi, E	1
Bummer, PM; Cervantes-Laurean, D; Coyle, DL; Jacobson, EL; Jacobson, MK; Strohm, MS	1
Okamoto, H; Takasawa, S; Tohgo, A	1
Abe, H; Akabane, A; Kato, I; Nata, K; Suzuki, Y; Takamura, T; Takasawa, S; Tanaka, O; Yonekura, H; Yoshimoto, T	1
Galione, A; Lee, HC; Sethi, JK; Walseth, TF; White, AM; Willmott, N	1
Bak, J; Galione, A; Genazzani, AA	1
Berggren, PO; Brown, G; Efanov, AM; Islam, MS; Köhler, M; Larsson, O; Webb, DL	1
Chae, SW; Cho, KP; Eun, JS; Han, MK; Kim, UH; Kwak, YG; Park, SK	1
Augustin, A; Muller-Steffner, HM; Schuber, F	1
De Flora, A; Franco, L; Guida, L; Piccini, D; Tacchetti, C; Zocchi, E	1
Chini, EN; de Toledo, FG; Dousa, TP; Thompson, MA	1
Crawford, JH; Scott, RH; Seabrook, GR; Wootton, JF	1
Mészáros, LG; Váradi, G; Wrenn, RW	1
Coyle, DL; Jacobson, EL; Jacobson, MK; Tai, HH; Vu, CQ	1
Campbell, WB; Li, P; Zou, AP	1
Coyle, DL; Jacobson, EL; Jacobson, MK; Kim, H; Vu, CQ	1
Ashamu, GA; Galione, A; Potter, BV; Sethi, JK	1
Faivre, JF; Guibert, J; Lahouratate, P	1
Aarhus, R; Dickey, DM; Lee, HC; Walseth, TF	1
Hashii, M; Higashida, H; Higashida, M; Noda, M; Ohshima, T; Okamoto, H; Takasawa, S; Takayasu, T; Taketo, M; Yokoyama, S	1
Baux, G; Fossier, P; Meunier, FM; Mothet, JP; Stinnakre, J; Tauc, L	1
Galione, A; Wilson, HL	1
Albrieux, M; Lee, HC; Villaz, M	1
Bubis, M; Zisapel, N	1
Campbell, WB; Li, PL; Zou, AP	1
Lee, HC; Munshi, C; Sauve, AA; Schramm, VL	1
Bolognesi, M; Coda, A; Rizzi, M	1
Bruzzone, S; De Flora, A; Franco, L; Guida, L; Usai, C; Zocchi, E	2
Matsumura, N; Tanuma, S	1
Kierzek, R; Phizicky, EM; Spinelli, SL; Turner, DH	1
Howard, MC; Lund, FE; Muller-Steffner, HM; Schuber, F; Stout, CD; Yu, N	1
Adebanjo, OA; Anandatheerthavarada, HK; Arakawa, T; Bevis, PJ; Biswas, G; Corisdeo, S; Epstein, S; Hakeda, Y; Koval, A; Kumegawa, M; Lai, FA; Moonga, BS; Moser, AJ; Sodam, B; Sun, L; Troen, BR; Zaidi, M	1
Cheng, J; Chini, EN; Dousa, TP; Liang, M	1
Okamoto, H	3
Adebanjo, OA; Anandatheerthavarada, HK; Avadhani, NG; Bevis, PJ; Biswas, G; Epstein, S; Huang, CL; Koval, AP; Lai, FA; Moonga, BS; Sodam, BR; Sun, L; Zaidi, M	1
Hashii, M; Higashida, H; Minabe, Y	1
Ziegler, M	1
Cho, YS; Han, MK; Kim, UH; Kim, YS; Yim, CY	1
Kato, I; Nata, K; Noguchi, N; Okamoto, H; Takasawa, S; Tohgo, A	1
Brusasco, V; Bruzzone, S; Crimi, E; De Flora, A; Franco, L; Guida, L; Song, P; Usai, C; Walseth, TF; Zocchi, E	1
Epel, D	1
Kumasaka, S; Okabe, E; Shoji, H	1
Bruzzone, S; Costa, A; De Flora, A; Franco, L; Guida, L; Usai, C; Zocchi, E	1
Mariani, P; Navazio, L; Sanders, D	1
An, NH; Han, MK; Kim, HK; Kim, UH; Park, BH; Park, BJ; Um, C	1
D'Andrea, P; Franco, L; Moro, L; Padoan, M; Romanello, M; Veronesi, V	1
Bruzzone, S; De Flora, A; Fedele, E; Matteoli, M; Schenk, U; Verderio, C; Zocchi, E	1
Cakir-Kiefer, C; Muller-Steffner, H; Oppenheimer, N; Schuber, F	1
Bisso, A; Bruzzone, S; Contini, P; De Flora, A; Franco, L; Guida, L; Usai, C; Zocchi, E	1
Cockayne, DA; Garvy, B; Goodrich, S; Harmsen, A; Howard, M; Jacobson, EL; Kusser, K; Lund, FE; Monard, S; Oppenheimer, N; Partida-Sánchez, S; Randall, TD	1
Graeff, R; Lee, HC	1
Esguerra, M; Miller, RF	1
Graeff, RM; Lee, HC	2
Bruzzone, S; De Flora, A; Graeff, R; Lee, HC; Usai, C	1
Galione, A; Migaud, ME; Mort, CJ; Potter, BV	1
Gao, JL; Iribarren, P; Lund, FE; Moreno-García, ME; Murphy, PM; Oppenheimer, N; Partida-Sánchez, S; Wang, JM	1
Guse, AH	2
Bobalova, J; Lew, C; Mendoza, MG; Mutafova-Yambolieva, VN; Smyth, LM	1
Bacigalupo, A; Benvenuto, F; Bodrato, N; Bruzzone, S; De Flora, A; Figari, O; Franco, L; Guida, L; Paleari, L; Pitto, A; Podestà, M; Usai, C; Zocchi, E	1
Bruzzone, S; De Flora, A; Franco, L; Guida, L; Zocchi, E	1
Goodrich, SP; Kellenberger, E; Kusser, K; LoVerde, PT; Lund, FE; Moutin, MJ; Muller-Steffner, H; Osman, A; Randall, TD; Roberts, A; Schuber, F; Woodland, DL	1
Lund, FE; Moutin, MJ; Muller-Steffner, H; Schuber, F	1
Bruzzone, S; De Flora, A; Guida, L; Moreschi, I; Usai, C; Zocchi, E	1
Baratier, J; Ceni, C; De Waard, M; Moutin, MJ; Muller-Steffner, H; Pochon, N; Ronjat, M; Schuber, F; Villaz, M	1
Hu, S; Peterson, PK; Shideman, CR; Thayer, SA	1
Lund, FE; Makris, M; Moreno-García, ME; Muller-Steffner, H; Oppenheimer, NJ; Partida-Sánchez, S; Romero-Ramirez, H; Santos-Argumedo, L; Schuber, F	1
Choleris, E; Kirkland, JB; Lund, FE; Young, GS	1
Hashii, M; Higashida, H; Jin, D; Noda, M; Salmina, A; Yokoyama, S; Zhang, JS; Zhong, ZG	1
Benvenuto, F; Bruzzone, S; De Flora, A; Fruscione, F; Kassack, MU; Meis, S; Moreschi, I; Nicholas, RA; Sturla, L; Usai, C; Zocchi, E	1
Graeff, R; Hao, Q; Kriksunov, IA; Lee, HC; Liu, Q; Munshi, C	1
Iqbal, J; Zaidi, M	1
Kellenberger, E; Kuhn, I; Lund, FE; Muller-Steffner, H; Rognan, D; Schuber, F	1
Graeff, R; Hao, Q; Kriksunov, IA; Lee, HC; Liu, Q	1
Lund, FE; Partidá-Sánchez, S; Rivero-Nava, L; Shi, G	1
Jacobson, EL; Kirkland, JB; Young, GS	1
Forouhar, F; Khan, JA; Tao, X; Tong, L	1
Chung, WG; Han, MK; Kim, JS; Kim, UH; Lee, SJ; Lee, YR; Park, KH; Park, YM; Rah, SY; Shim, IK; Song, EK; Yu, HN	1
Jude, JA; Kang, BN; Kannan, MS; Panettieri, RA; Walseth, TF	1
Barranco, WT; Eckhert, CD; Kim, DH; Stella, SL	1
Lam, CM; Lee, HC; Wong, JT; Yeung, PK	1
Graeff, R; Hao, Q; Kotaka, M; Kriksunov, IA; Lee, HC; Liu, Q; Oppenheimer, N	1
Dewey, WL; Gabra, BH; Hull, LC; Li, PL; Rabender, C; Zhang, F	1
Csanády, L; Tóth, B	1
Durnin, L; Mutafova-Yambolieva, VN	1
Han, MK; Kim, JS; Kim, UH; Kim, YR; Lee, YR; Park, KH; Rah, SY; Song, EK; Yeom, JH; Yoo, CH	1
Ikeda, T; Nata, K; Noguchi, N; Okamoto, H; Sugawara, A; Takahashi, I; Takasawa, S; Yamauchi, A; Yonekura, H; Yoshikawa, T	1
Bauer, I; Brini, M; Bruzzone, S; De Flora, A; Magnone, M; Mannino, E; Nencioni, A; Poggi, A; Sturla, L; Zocchi, E	1
Azhar, N; Billiar, TR; Clermont, T; Constantine, G; Fink, MP; Gladstone, C; Hermus, L; Megas, C; Metukuri, MR; Namas, R; Namas, RA; Vodovotz, Y; Zamora, R	1
Barski, OA; Bhatnagar, A; Kilfoil, PJ; Tipparaju, SM	1
Bruzzone, S; Guse, AH	1
Guse, AH; Kirchberger, T	1
Jiang, J; Ma, Y; Ying, W	1
Kuz'min, VS; Pustovit, KB; Sukhova, GS	1
Choi, BH; Lee, H; Lee, JK; Lee, JS; Oh, ET; Park, HJ; Park, MT	1
Becherer, JD; Billin, AN; Carpenter, T; Chen, J; Chiang, SH; Geske, RS; Haffner, CD; Harrington, WW; Kramer, HF; Luo, G; Milliken, NO; Murray, R; Preugschat, F; Qian, Y; Rajpal, DK; Stimpson, SA; Ulrich, JC	1
Graeff, RM; Hao, Q; Kotaka, M; Lee, HC; Leung, CF; Ting, KY	1
Ai, ML; Ai, YH; Ma, XH; Peng, QY; Zhang, LN; Zou, Y	1
Guarente, L; Igarashi, M	1
Chini, CCS; Chini, EN; Tarragó, MG	1
Anderson, RG; Chung, EH; Dangl, JL; DiAntonio, A; Essuman, K; Milbrandt, J; Monteiro, F; Nishimura, MT; Osborne Nishimura, E; Sasaki, Y; Wan, L	1
Gao, W; Huang, C; Huber, PE; Li, C; Shen, G; Xie, N; Zhang, L; Zhou, X; Zou, B	1
Bolze, S; Fouqueray, P; Hallakou-Bozec, S; Kergoat, M; Moller, DE	1
Okamoto, H; Takasawa, S	1
Amitai, G; Baroz, M; Cohen, D; Doron, S; Herbst, E; Malheiro, DBA; Malitsky, S; Millman, A; Ofir, G; Sorek, R; Tal, N	1
Li, X; Liao, Q; Zeng, F; Zhou, Y; Zhu, L	1
Ahmed, T; Barratt, MJ; Buchser, W; Damaraju, N; DiAntonio, A; Gordon, JI; Milbrandt, J; Osterman, A; Rodionov, DA; Sasaki, Y; Venkatesh, S; Weagley, JS; Yenkin, A; Zaydman, M	1
Burdett, H; Damaraju, N; DiAntonio, A; Eastman, S; Grant, M; Gu, W; Guo, M; Hancock, SJ; Hartley-Tassell, L; Kargios, N; Kobe, B; Landsberg, MJ; Li, S; Lim, BYJ; Manik, MK; Maruta, N; Masic, V; Milbrandt, J; Mosaiab, T; Nanson, JD; Prokes, I; Schembri, MA; Shi, Y; Smith, TG; Song, L; Vasquez, E; Ve, T; Weagley, JS; Zaydman, MA	1
Astigiano, C; Benzi, A; Bruzzone, S; De Flora, A; Guida, L; Laugieri, ME; Piacente, F; Sturla, L	1
Andy, D; Gunaratne, GS; Marchant, JS; Slama, JT; Walseth, TF	1
Gerasimenko, M; Higashida, H	1
Hara, Y; Higashi, T; Konishi, Y; Mori, Y; Togashi, K; Tominaga, M; Tominaga, T	1

Reviews

21 review(s) available for nad and cyclic adp-ribose

Article	Year
Cyclic ADP-ribose: a calcium mobilizing metabolite of NAD+. Molecular and cellular biochemistry, 1994, Volume: 138, Issue:1-2 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cyclic ADP-Ribose; Humans; Membrane Glycoproteins; Molecular Structure; N-Glycosyl Hydrolases; NAD; Receptors, Cell Surface	1994
NAD glycohydrolases and the metabolism of cyclic ADP-ribose. Biochimie, 1995, Volume: 77, Issue:5 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Humans; NAD; NAD+ Nucleosidase; Signal Transduction	1995
New aspects of the physiological significance of NAD, poly ADP-ribose and cyclic ADP-ribose. Biochimie, 1995, Volume: 77, Issue:5 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Aplysia; Cyclic ADP-Ribose; Endoplasmic Reticulum; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Glycoproteins; Mice; Models, Biological; Molecular Sequence Data; N-Glycosyl Hydrolases; NAD; Poly Adenosine Diphosphate Ribose; Rats; Sequence Homology, Amino Acid	1995
Intramolecular ADP-ribose transfer reactions and calcium signalling. Potential role of 2'-phospho-cyclic ADP-ribose in oxidative stress. Advances in experimental medicine and biology, 1997, Volume: 419 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cattle; Cyclic ADP-Ribose; NAD; NADP; Oxidative Stress; Signal Transduction	1997
Calcium signaling by cyclic ADP-ribose and NAADP. A decade of exploration. Cell biochemistry and biophysics, 1998, Volume: 28, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Humans; Models, Molecular; NAD; Signal Transduction	1998
["The CD38-cyclic ADP-ribose signal system": molecular mechanism and biological significance]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1999, Volume: 114, Issue:3 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cyclic ADP-Ribose; Insulin; Insulin Secretion; Islets of Langerhans; Microsomes; NAD; NAD+ Nucleosidase; Ryanodine Receptor Calcium Release Channel; Signal Transduction	1999
New functions of a long-known molecule. Emerging roles of NAD in cellular signaling. European journal of biochemistry, 2000, Volume: 267, Issue:6 Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Animals; Bacterial Toxins; Calcium Signaling; Cyclic ADP-Ribose; Eukaryotic Cells; Heterotrimeric GTP-Binding Proteins; Humans; Mitochondria; NAD; NADP; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Signal Transduction	2000
Topology of CD38. Chemical immunology, 2000, Volume: 75 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Biological Transport; Calcium; Cyclic ADP-Ribose; Homeostasis; Humans; Membrane Glycoproteins; NAD; NAD+ Nucleosidase; Sulfhydryl Compounds	2000
Physiological and pathological significance of the CD38-cyclic ADP-ribose signaling system. Chemical immunology, 2000, Volume: 75 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic ADP-Ribose; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Glycoproteins; Molecular Sequence Data; Multienzyme Complexes; NAD; NAD+ Nucleosidase	2000
[Pancreatic beta-cell death, regeneration and functioning]. Seikagaku. The Journal of Japanese Biochemical Society, 2003, Volume: 75, Issue:10 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Autoantibodies; Cell Death; Cyclic ADP-Ribose; Diabetes Mellitus; DNA Damage; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Lectins, C-Type; Membrane Glycoproteins; Mutation; NAD; Poly(ADP-ribose) Polymerases; Regeneration; Second Messenger Systems; Transcription Factors	2003
Biochemistry, biology, and pharmacology of cyclic adenosine diphosphoribose (cADPR). Current medicinal chemistry, 2004, Volume: 11, Issue:7 Topics: ADP-ribosyl Cyclase; Animals; Calcium; Cyclic ADP-Ribose; Humans; Ligands; Models, Biological; NAD; Ryanodine Receptor Calcium Release Channel; Signal Transduction	2004
Recent advances in physiological and pathological significance of tryptophan-NAD+ metabolites: lessons from insulin-producing pancreatic beta-cells. Advances in experimental medicine and biology, 2003, Volume: 527 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Cyclic ADP-Ribose; Diabetes Mellitus, Experimental; DNA Repair; Humans; Insulin; Islets of Langerhans; Membrane Glycoproteins; Models, Biological; NAD; Poly Adenosine Diphosphate Ribose; Signal Transduction; Tryptophan	2003
Autocrine and paracrine calcium signaling by the CD38/NAD+/cyclic ADP-ribose system. Annals of the New York Academy of Sciences, 2004, Volume: 1028 Topics: 3T3 Cells; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Biological Transport; Calcium; Cell Membrane; Cells, Cultured; Connexin 43; Cyclic ADP-Ribose; Fibroblasts; Hematopoietic Stem Cells; Hippocampus; Humans; Membrane Glycoproteins; Mice; Models, Biological; NAD; Neurons; Paracrine Communication; Ryanodine Receptor Calcium Release Channel; Signal Transduction	2004
CD38: an ecto-enzyme at the crossroads of innate and adaptive immune responses. Advances in experimental medicine and biology, 2007, Volume: 590 Topics: ADP-ribosyl Cyclase 1; Animals; Bacteremia; Calcium Signaling; Chemokines; Chemotaxis; Cyclic ADP-Ribose; Dendritic Cells; Extracellular Fluid; Humans; Immunity, Innate; Immunization; Infections; Inflammation; Lung; Membrane Glycoproteins; Mice; Mice, Knockout; Mice, Transgenic; Models, Immunological; NAD; Neutrophils; Pneumonia, Pneumococcal; Receptors, Chemokine; Substrate Specificity; T-Lymphocyte Subsets	2007
Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery. Expert opinion on therapeutic targets, 2007, Volume: 11, Issue:5 Topics: Acrylamides; Adenosine Diphosphate Ribose; Aging; Animals; Antineoplastic Agents; Autoimmune Diseases; Clinical Trials, Phase II as Topic; Cyclic ADP-Ribose; DNA Damage; Drug Design; Enzyme Inhibitors; Humans; Kynurenine; Mice; NAD; Neoplasms; Neurodegenerative Diseases; Neuroprotective Agents; Piperidines; Poly Adenosine Diphosphate Ribose; Signal Transduction; Sirtuins; Tryptophan	2007
Regulation of ion channels by pyridine nucleotides. Circulation research, 2013, Feb-15, Volume: 112, Issue:4 Topics: Animals; Binding Sites; Calcium Signaling; Carrier Proteins; Cations; Cyclic ADP-Ribose; Eukaryotic Cells; Homeostasis; Humans; Ion Channel Gating; Ion Channels; Ion Transport; Mammals; NAD; NADP; Phosphorylation; Potassium; Prokaryotic Cells; Sodium	2013
Calcium mobilizing second messengers derived from NAD. Biochimica et biophysica acta, 2015, Volume: 1854, Issue:9 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Humans; NAD; NADP; Second Messenger Systems	2015
NAD and the aging process: Role in life, death and everything in between. Molecular and cellular endocrinology, 2017, Nov-05, Volume: 455 Topics: ADP-ribosyl Cyclase 1; Aging; Animals; Armadillo Domain Proteins; Caloric Restriction; Cyclic ADP-Ribose; Cytoskeletal Proteins; Humans; Membrane Glycoproteins; Mitochondria; NAD; NADP; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Signal Transduction; Sirtuins	2017
NAD Signal transduction and targeted therapy, 2020, 10-07, Volume: 5, Issue:1 Topics: Aging; Cyclic ADP-Ribose; Humans; Metabolic Diseases; NAD; NADP; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction	2020
Adenosine diphosphate ribose cyclase: An important regulator of human pathological and physiological processes. Journal of cellular physiology, 2022, Volume: 237, Issue:4 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Calcium Signaling; Cyclic ADP-Ribose; Humans; NAD; Physiological Phenomena	2022
Paracrine ADP Ribosyl Cyclase-Mediated Regulation of Biological Processes. Cells, 2022, 08-24, Volume: 11, Issue:17 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Biological Phenomena; Connexin 43; Cyclic ADP-Ribose; Mammals; Membrane Glycoproteins; NAD	2022

Other Studies

114 other study(ies) available for nad and cyclic adp-ribose

Article	Year
ADP-ribosyl cyclase: an enzyme that cyclizes NAD+ into a calcium-mobilizing metabolite. Cell regulation, 1991, Volume: 2, Issue:3 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Aplysia; Calcium; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Electrophoresis, Polyacrylamide Gel; Kinetics; Magnetic Resonance Spectroscopy; N-Glycosyl Hydrolases; NAD; Niacinamide; Second Messenger Systems	1991
Novel mechanism of intracellular calcium release in pituitary cells. The Journal of biological chemistry, 1991, Sep-15, Volume: 266, Issue:26 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cell Line; Cell Membrane Permeability; Cyclic ADP-Ribose; Inositol 1,4,5-Trisphosphate; NAD; Pituitary Gland; Rats; Rats, Inbred Strains; Second Messenger Systems	1991
Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activity. The Journal of biological chemistry, 1989, Jan-25, Volume: 264, Issue:3 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; NAD; Oocytes; Sea Urchins	1989
Agonist-stimulated cyclic ADP ribose. Endogenous modulator of Ca(2+)-induced Ca2+ release in intestinal longitudinal muscle. The Journal of biological chemistry, 1995, Oct-27, Volume: 270, Issue:43 Topics: Adenosine Diphosphate Ribose; Animals; Benzodiazepinones; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Membrane Permeability; Cyclic ADP-Ribose; Devazepide; Dose-Response Relationship, Drug; Guanosine Diphosphate; Heparin; Intestine, Small; Muscle Contraction; Muscle, Smooth; NAD; Nifedipine; Rabbits; Ruthenium Red; Sincalide; Subcellular Fractions; Thionucleotides	1995
cGMP mobilizes intracellular Ca2+ in sea urchin eggs by stimulating cyclic ADP-ribose synthesis. Nature, 1993, Sep-30, Volume: 365, Issue:6445 Topics: Adenosine Diphosphate Ribose; Aniline Compounds; Animals; Calcium; Cyclic ADP-Ribose; Cyclic GMP; Fluorometry; In Vitro Techniques; Microsomes; NAD; Ovum; Ruthenium Red; Sea Urchins; Signal Transduction; Xanthenes	1993
Nicotinamide-adenine dinucleotide regulates muscarinic receptor-coupled K+ (M) channels in rodent NG108-15 cells. The Journal of physiology, 1995, Jan-15, Volume: 482 ( Pt 2) Topics: Adenosine Diphosphate Ribose; Animals; Cyclic ADP-Ribose; Mice; NAD; Potassium Channels; Receptors, Muscarinic; Streptozocin; Swine; Tumor Cells, Cultured	1995
The kinetics of cyclic ADP-ribose formation in heart muscle. Biochemical and biophysical research communications, 1995, May-16, Volume: 210, Issue:2 Topics: Adenosine Diphosphate Ribose; Animals; Cyclic ADP-Ribose; In Vitro Techniques; Kinetics; Male; Myocardium; NAD; Rats; Rats, Sprague-Dawley	1995
Cyclic ADP-ribose and related compounds activate sheep skeletal sarcoplasmic reticulum Ca2+ release channel. The American journal of physiology, 1995, Volume: 268, Issue:5 Pt 1 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cyclic ADP-Ribose; Muscle, Skeletal; NAD; Osmolar Concentration; Sarcoplasmic Reticulum; Sheep	1995
Ligation of CD38 suppresses human B lymphopoiesis. The Journal of experimental medicine, 1995, Mar-01, Volume: 181, Issue:3 Topics: Adenosine Diphosphate Ribose; Adolescent; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Adult; Antigens, CD; Antigens, Differentiation; Apoptosis; B-Lymphocytes; Cell Division; Cells, Cultured; Child; Child, Preschool; Cyclic ADP-Ribose; Hematopoiesis; Hematopoietic Stem Cells; Humans; Infant; Membrane Glycoproteins; NAD	1995
Metabolism of cyclic ADP-ribose in opossum kidney renal epithelial cells. The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 1 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Biological Assay; Calcium; Carrier Proteins; Cell Line; Cell Membrane Permeability; Cyclic ADP-Ribose; Epithelium; Kidney; N-Glycosyl Hydrolases; NAD; Niacinamide; Opossums; Ovum; Parathyroid Hormone; Sea Urchins; Sodium-Phosphate Cotransporter Proteins; Symporters	1995
Cyclic ADP-ribose does not affect cardiac or skeletal muscle ryanodine receptors. FEBS letters, 1994, Sep-26, Volume: 352, Issue:2 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cyclic ADP-Ribose; Lipid Bilayers; Muscle Proteins; Myocardium; NAD; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Swine	1994
Mechanistic implications of cyclic ADP-ribose hydrolysis and methanolysis catalyzed by calf spleen NAD+glycohydrolase. Biochemical and biophysical research communications, 1994, Nov-15, Volume: 204, Issue:3 Topics: Adenosine Diphosphate Ribose; Animals; Carbon Radioisotopes; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Hydrolysis; Kinetics; Methane; NAD; NAD+ Nucleosidase; Spleen	1994
Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38. Science (New York, N.Y.), 1993, Nov-12, Volume: 262, Issue:5136 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; B-Lymphocytes; Calcium; Cyclic ADP-Ribose; Lymphocyte Activation; Membrane Glycoproteins; Mice; Molecular Sequence Data; N-Glycosyl Hydrolases; NAD; Recombinant Proteins	1993
Human lymphocyte antigen CD38 catalyzes the production of cyclic ADP-ribose. FEBS letters, 1993, Dec-06, Volume: 335, Issue:2 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Catalysis; Cell Line; Chlorocebus aethiops; Cyclic ADP-Ribose; Humans; Membrane Glycoproteins; NAD; Sea Urchins	1993
An NAD derivative produced during transfer RNA splicing: ADP-ribose 1"-2" cyclic phosphate. Science (New York, N.Y.), 1993, Jul-09, Volume: 261, Issue:5118 Topics: Adenosine Diphosphate Ribose; Animals; Cyclic ADP-Ribose; Endoribonucleases; NAD; Oocytes; Phosphates; Phosphorylation; Phosphotransferases; RNA Splicing; RNA, Fungal; RNA, Transfer; Saccharomyces cerevisiae; Xenopus	1993
Synthesis and degradation of cyclic ADP-ribose by NAD glycohydrolases. Science (New York, N.Y.), 1993, Sep-03, Volume: 261, Issue:5126 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Dogs; Hydrolysis; Kinetics; NAD; NAD+ Nucleosidase; Spleen	1993
Production and hydrolysis of cyclic ADP-ribose at the outer surface of human erythrocytes. Biochemical and biophysical research communications, 1993, Mar-15, Volume: 191, Issue:2 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cells, Cultured; Cyclic ADP-Ribose; Erythrocyte Membrane; Humans; Hydrolysis; Membrane Glycoproteins; Microsomes; N-Glycosyl Hydrolases; NAD; Ovum; Sea Urchins	1993
Wide distribution of an enzyme that catalyzes the hydrolysis of cyclic ADP-ribose. Biochimica et biophysica acta, 1993, Jun-24, Volume: 1164, Issue:1 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Brain; Calcium; Chick Embryo; Cyclic ADP-Ribose; Dogs; Hydrogen-Ion Concentration; Models, Chemical; N-Glycosyl Hydrolases; NAD; Niacinamide; Sea Urchins	1993
Regulatory role of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in insulin secretion by glucose in pancreatic beta cells. Enhanced insulin secretion in CD38-expressing transgenic mice. The Journal of biological chemistry, 1995, Dec-15, Volume: 270, Issue:50 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Cyclic ADP-Ribose; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Membrane Glycoproteins; Mice; Mice, Transgenic; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Potassium Chloride; Promoter Regions, Genetic; Rats; Reference Values; Subcellular Fractions; Tolbutamide	1995
Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway. The Journal of biological chemistry, 1996, Feb-16, Volume: 271, Issue:7 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cyclic ADP-Ribose; Cyclic GMP; Enzyme Inhibitors; Female; Guanosine Triphosphate; Isomerism; Kinetics; Mammals; Models, Biological; N-Glycosyl Hydrolases; NAD; Niacinamide; Nitric Oxide; Ovum; Sea Urchins; Signal Transduction; Thionucleotides; Time Factors	1996
Inhibition of cADPR-Hydrolase by ADP-ribose potentiates cADPR synthesis from beta-NAD+. Biochemical and biophysical research communications, 1996, Jun-25, Volume: 223, Issue:3 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cyclic ADP-Ribose; Enzyme Inhibitors; Female; Kinetics; Microsomes; N-Glycosyl Hydrolases; NAD; Ovum; Sea Urchins	1996
Insulin exocytosis and glucose-mediated increase in cytoplasmic free Ca2+ concentration in the pancreatic beta-cell are independent of cyclic ADP-ribose. The Journal of biological chemistry, 1996, Aug-09, Volume: 271, Issue:32 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Cytoplasm; Exocytosis; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Mice; Mice, Obese; NAD	1996
Intracellular ADP-ribose inhibits ATP-sensitive K+ channels in rat ventricular myocytes. The American journal of physiology, 1996, Volume: 271, Issue:2 Pt 1 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Cyclic ADP-Ribose; Heart Ventricles; Intracellular Membranes; Myocardium; NAD; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley	1996
Mechanism of cyclization of pyridine nucleotides by bovine spleen NAD+ glycohydrolase. The Journal of biological chemistry, 1996, Sep-27, Volume: 271, Issue:39 Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cyclic ADP-Ribose; Guanosine Diphosphate Sugars; NAD; NAD+ Nucleosidase; Spleen; Substrate Specificity	1996
NAD+-dependent internalization of the transmembrane glycoprotein CD38 in human Namalwa B cells. FEBS letters, 1996, Nov-04, Volume: 396, Issue:2-3 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; B-Lymphocytes; Cell Membrane; Cyclic ADP-Ribose; Down-Regulation; Endocytosis; Glutathione; Humans; Membrane Glycoproteins; Microscopy, Fluorescence; Microscopy, Immunoelectron; N-Glycosyl Hydrolases; NAD; Organelles; Tumor Cells, Cultured	1996
Effect of estrogen upon cyclic ADP ribose metabolism: beta-estradiol stimulates ADP ribosyl cyclase in rat uterus. Proceedings of the National Academy of Sciences of the United States of America, 1997, May-27, Volume: 94, Issue:11 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Brain; Calcium; Cell Nucleus; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Estradiol; Female; Kidney; Kinetics; Liver; Membrane Glycoproteins; Models, Biological; Muscle, Smooth; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Ovariectomy; Ovum; Parathyroidectomy; Rats; Rats, Sprague-Dawley; Receptors, Estradiol; Sea Urchins; Second Messenger Systems; Tamoxifen; Thyroidectomy; Uterus	1997
Activation of Ca2+-dependent currents in dorsal root ganglion neurons by metabotropic glutamate receptors and cyclic ADP-ribose precursors. Journal of neurophysiology, 1997, Volume: 77, Issue:5 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cells, Cultured; Cyclic ADP-Ribose; Cyclic GMP; Ganglia, Spinal; Glutamic Acid; Membrane Potentials; Muscle Proteins; NAD; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Ryanodine Receptor Calcium Release Channel; Synaptic Transmission	1997
Sarcoplasmic reticulum-associated and protein kinase C-regulated ADP-ribosyl cyclase in cardiac muscle. Biochemical and biophysical research communications, 1997, May-08, Volume: 234, Issue:1 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Cyclic ADP-Ribose; Dithiothreitol; Dogs; Electrophoresis, Polyacrylamide Gel; Guanine Nucleotides; Guanosine Diphosphate Sugars; Isoenzymes; Membrane Glycoproteins; Myocardium; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Phosphorylation; Protein Kinase C; Rats; Sarcoplasmic Reticulum	1997
Metabolism and actions of ADP-riboses in coronary arterial smooth muscle. Advances in experimental medicine and biology, 1997, Volume: 419 Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Coronary Vessels; Cyclic ADP-Ribose; Electrophysiology; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Muscle, Smooth, Vascular; NAD; Potassium Channels; Potassium Channels, Calcium-Activated; Vasodilator Agents	1997
Preparation of cyclic ADP-ribose, 2'-phospho-cyclic ADP-ribose, and nicotinate adenine dinucleotide phosphate: possible second messengers of calcium signaling. Methods in enzymology, 1997, Volume: 280 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Aplysia; Calcium; Cyclic ADP-Ribose; Cyclic AMP; Enzymes, Immobilized; Lyases; N-Glycosyl Hydrolases; NAD; NADP; Nucleotides, Cyclic; Second Messenger Systems	1997
Roles for adenosine ribose hydroxyl groups in cyclic adenosine 5'-diphosphate ribose-mediated Ca2+ release. Biochemistry, 1997, Aug-05, Volume: 36, Issue:31 Topics: Adenosine Diphosphate Ribose; Animals; Aplysia; Calcium; Cyclic ADP-Ribose; Hydrogen Bonding; Hydroxyl Radical; NAD; Sea Urchins; Spectrum Analysis; Structure-Activity Relationship	1997
cADP-ribose releases Ca2+ from cardiac sarcoplasmic reticulum independently of ryanodine receptor. The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2 Topics: Adenosine Diphosphate Ribose; Aniline Compounds; Animals; Calcimycin; Calcium; Calcium Channel Agonists; Calcium Channels; Carbolines; Cyclic ADP-Ribose; Dogs; Drug Synergism; Fluorescent Dyes; Kinetics; Microsomes; Models, Cardiovascular; Muscle Proteins; Myocardium; NAD; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Xanthenes	1997
Thio-NADP is not an antagonist of NAADP. Cell biochemistry and biophysics, 1998, Volume: 28, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Anion Exchange Resins; Calcium; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cyclic ADP-Ribose; Drug Contamination; NAD; NADP; Oocytes; Resins, Synthetic; Sea Urchins	1998
Muscarinic receptor-mediated dual regulation of ADP-ribosyl cyclase in NG108-15 neuronal cell membranes. The Journal of biological chemistry, 1997, Dec-12, Volume: 272, Issue:50 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Cell Line; Cell Membrane; Chromatography, Thin Layer; COS Cells; Cyclic ADP-Ribose; Humans; Membrane Glycoproteins; Multienzyme Complexes; NAD; NAD+ Nucleosidase; Neurons; Receptors, Muscarinic; Transfection	1997
Cyclic ADP-ribose and calcium-induced calcium release regulate neurotransmitter release at a cholinergic synapse of Aplysia. The Journal of physiology, 1998, Mar-01, Volume: 507 ( Pt 2) Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Aplysia; Calcium; Cyclic ADP-Ribose; Electrophysiology; Fluorescent Dyes; Ganglia, Invertebrate; Membrane Potentials; NAD; Neurotransmitter Agents; Parasympathetic Nervous System; Patch-Clamp Techniques; Polymerase Chain Reaction; Receptors, Presynaptic; Ryanodine Receptor Calcium Release Channel; Synapses	1998
Differential regulation of nicotinic acid-adenine dinucleotide phosphate and cADP-ribose production by cAMP and cGMP. The Biochemical journal, 1998, May-01, Volume: 331 ( Pt 3) Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Cyclic AMP; Cyclic GMP; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Niacin; Oocytes; Sea Urchins; Second Messenger Systems; Temperature	1998
Calcium signaling by cyclic ADP-ribose, NAADP, and inositol trisphosphate are involved in distinct functions in ascidian oocytes. The Journal of biological chemistry, 1998, Jun-05, Volume: 273, Issue:23 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Chelating Agents; Cyclic ADP-Ribose; Electrophysiology; Fertilization; Inositol 1,4,5-Trisphosphate; NAD; NAD+ Nucleosidase; NADP; Oocytes; Patch-Clamp Techniques; Ryanodine; Signal Transduction; Urochordata	1998
A role for NAD+ and cADP-ribose in melatonin signal transduction. Molecular and cellular endocrinology, 1998, Volume: 137, Issue:1 Topics: Adenosine Diphosphate Ribose; Cyclic ADP-Ribose; Humans; Melanoma; Melatonin; NAD; Signal Transduction; Tumor Cells, Cultured	1998
Regulation of KCa-channel activity by cyclic ADP-ribose and ADP-ribose in coronary arterial smooth muscle. The American journal of physiology, 1998, Volume: 275, Issue:3 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; Animals; Calcium; Cattle; Chromatography, High Pressure Liquid; Coronary Vessels; Cyclic ADP-Ribose; Cytosol; Electric Conductivity; Kinetics; Membrane Potentials; Microsomes; Muscle, Smooth, Vascular; NAD; NAD+ Nucleosidase; Phosphorus-Oxygen Lyases; Potassium Channels	1998
The reaction mechanism for CD38. A single intermediate is responsible for cyclization, hydrolysis, and base-exchange chemistries. Biochemistry, 1998, Sep-22, Volume: 37, Issue:38 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Binding, Competitive; Catalysis; Cyclic ADP-Ribose; Fluorescence Polarization; Guanosine Diphosphate Sugars; Humans; Hydrolysis; Kinetics; Membrane Glycoproteins; Methanol; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Spectrometry, Fluorescence; Substrate Specificity	1998
A novel deamido-NAD+-binding site revealed by the trapped NAD-adenylate intermediate in the NAD+ synthetase structure. Structure (London, England : 1993), 1998, Sep-15, Volume: 6, Issue:9 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Amide Synthases; Bacillus subtilis; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cyclic ADP-Ribose; Models, Molecular; Molecular Sequence Data; NAD; Protein Conformation	1998
The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:14 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Biological Transport; Catalysis; Cyclic ADP-Ribose; Erythrocyte Membrane; Guanosine Diphosphate Sugars; HeLa Cells; Humans; Membrane Glycoproteins; NAD; NAD+ Nucleosidase; Proteolipids; Second Messenger Systems	1998
Involvement of cytosolic NAD+ glycohydrolase in cyclic ADP-ribose metabolism. Biochemical and biophysical research communications, 1998, Dec-18, Volume: 253, Issue:2 Topics: Adenosine Diphosphate Ribose; Allosteric Site; Animals; Brain; Cattle; Cyclic ADP-Ribose; Cytosol; Enzyme Activation; Hydrolysis; Kinetics; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Substrate Specificity	1998
Transient ADP-ribosylation of a 2'-phosphate implicated in its removal from ligated tRNA during splicing in yeast. The Journal of biological chemistry, 1999, Jan-29, Volume: 274, Issue:5 Topics: Adenosine Diphosphate Ribose; Animals; Cyclic ADP-Ribose; Escherichia coli; Escherichia coli Proteins; Mice; NAD; Phosphotransferases (Alcohol Group Acceptor); RNA Splicing; RNA, Transfer; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Tumor Protein, Translationally-Controlled 1	1999
CD38 signaling in B lymphocytes is controlled by its ectodomain but occurs independently of enzymatically generated ADP-ribose or cyclic ADP-ribose. Journal of immunology (Baltimore, Md. : 1950), 1999, Mar-01, Volume: 162, Issue:5 Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Antigens, CD; B-Lymphocytes; CD48 Antigen; Cyclic ADP-Ribose; Mice; Molecular Sequence Data; NAD; Rabbits; Signal Transduction; Transfection	1999
CD38/ADP-ribosyl cyclase: A new role in the regulation of osteoclastic bone resorption. The Journal of cell biology, 1999, Sep-06, Volume: 146, Issue:5 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Animals, Newborn; Antigens, CD; Antigens, Differentiation; Base Sequence; Bone Resorption; Calcium Signaling; Cell Membrane; Cells, Cultured; Cloning, Molecular; Cyclic ADP-Ribose; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Interleukin-6; Membrane Glycoproteins; Molecular Sequence Data; NAD; NAD+ Nucleosidase; Osteoclasts; Rabbits; Rats; Rats, Wistar; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Sequence Homology, Amino Acid	1999
Synthesis of NAADP and cADPR in mitochondria. Archives of biochemistry and biophysics, 1999, Nov-15, Volume: 371, Issue:2 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Cell Compartmentation; Cell Membrane; Cyclic ADP-Ribose; Dithiothreitol; Glycosylphosphatidylinositols; Guanine Nucleotides; Isoenzymes; Membrane Glycoproteins; Mitochondria, Liver; Multienzyme Complexes; NAD; NAD+ Nucleosidase; NADP; Niacinamide; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Rats; Rats, Sprague-Dawley; Type C Phospholipases	1999
A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasis. Nature cell biology, 1999, Volume: 1, Issue:7 Topics: 3T3 Cells; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cell Fractionation; Cell Nucleus; Cyclic ADP-Ribose; Genes, Reporter; Immunoblotting; Inositol 1,4,5-Trisphosphate; Membrane Glycoproteins; Mice; Microscopy, Confocal; Multienzyme Complexes; NAD; NAD+ Nucleosidase; Nuclear Envelope; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel	1999
cADP-ribose potentiates cytosolic Ca2+ elevation and Ca2+ entry via L-type voltage-activated Ca2+ channels in NG108-15 neuronal cells. The Biochemical journal, 2000, Jan-15, Volume: 345 Pt 2 Topics: Adenosine Diphosphate Ribose; Biological Transport; Calcium; Calcium Channels, L-Type; Cells, Cultured; Cyclic ADP-Ribose; Cytosol; Ion Channel Gating; Manganese; Membrane Potentials; Models, Biological; NAD; Neurons; Niacinamide; Nifedipine; Patch-Clamp Techniques; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tacrolimus	2000
Interaction of two classes of ADP-ribose transfer reactions in immune signaling. The Journal of biological chemistry, 2000, Jul-07, Volume: 275, Issue:27 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Apoptosis; Arginine; Calcium; Cell Line; Cyclic ADP-Ribose; Cysteine; Flow Cytometry; Humans; Lymphocyte Activation; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NAD; NAD+ Nucleosidase; Phosphatidylinositol Diacylglycerol-Lyase; Poly(ADP-ribose) Polymerases; Signal Transduction; T-Lymphocytes; Transfection; Type C Phospholipases	2000
Extracellular cyclic ADP-ribose potentiates ACh-induced contraction in bovine tracheal smooth muscle. American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 280, Issue:1 Topics: Acetylcholine; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Bronchoconstriction; Calcium; Cattle; Cyclic ADP-Ribose; Extracellular Space; In Vitro Techniques; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Smooth; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Paracrine Communication; Receptor Cross-Talk; Respiratory Mucosa; Trachea; Vasodilator Agents	2001
How the sperm triggers development of the egg: what have we learned and what can we expect in the next millennium? Zygote (Cambridge, England), 2000, Volume: 8 Suppl 1 Topics: Adenosine Diphosphate Ribose; Animals; Calcium Signaling; Cyclic ADP-Ribose; Cyclic GMP; Embryology; Forecasting; Inositol 1,4,5-Trisphosphate; Microinjections; NAD; Nitric Oxide; Oocytes; Phosphatidylinositol Diacylglycerol-Lyase; Sea Urchins; Sperm-Ovum Interactions; Type C Phospholipases; Zygote	2000
Novel mechanisms involved in superoxide anion radical-triggered Ca2+ release from cardiac sarcoplasmic reticulum linked to cyclic ADP-ribose stimulation. Antioxidants & redox signaling, 1999,Spring, Volume: 1, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Calmodulin; Cyclic ADP-Ribose; Dogs; Electron Spin Resonance Spectroscopy; Hypoxanthine; Myocardium; NAD; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Superoxide Dismutase; Superoxides; Xanthine Oxidase	1999
Paracrine roles of NAD+ and cyclic ADP-ribose in increasing intracellular calcium and enhancing cell proliferation of 3T3 fibroblasts. The Journal of biological chemistry, 2001, Jun-15, Volume: 276, Issue:24 Topics: 3T3 Cells; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Binding Sites; Calcium; Cell Division; Cell Membrane; Coculture Techniques; Connexin 43; Cyclic ADP-Ribose; Cytosol; Kinetics; Membrane Glycoproteins; Mice; Models, Biological; Multienzyme Complexes; NAD; NAD+ Nucleosidase; Oligodeoxyribonucleotides, Antisense; Recombinant Proteins; Transfection	2001
Mobilization of Ca2+ by cyclic ADP-ribose from the endoplasmic reticulum of cauliflower florets. Plant physiology, 2001, Volume: 125, Issue:4 Topics: Adenosine Diphosphate Ribose; Brassica; Calcium; Cell Fractionation; Cyclic ADP-Ribose; Endoplasmic Reticulum, Rough; Intracellular Membranes; Kinetics; Microsomes; NAD; Plant Stems; Vacuoles	2001
Significance of ecto-cyclase activity of CD38 in insulin secretion of mouse pancreatic islet cells. Biochemical and biophysical research communications, 2001, Apr-06, Volume: 282, Issue:3 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Cyclic ADP-Ribose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NAD; NAD+ Nucleosidase; Second Messenger Systems	2001
Extracellular NAD(+) induces calcium signaling and apoptosis in human osteoblastic cells. Biochemical and biophysical research communications, 2001, Aug-03, Volume: 285, Issue:5 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Apoptosis; Calcium; Calcium Signaling; Cell Count; Cell Division; Cell Line; Chelating Agents; Cyclic ADP-Ribose; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Fluorescent Dyes; Fura-2; Humans; Membrane Glycoproteins; Microscopy, Video; NAD; NAD+ Nucleosidase; Osteoblasts; Ryanodine; Stimulation, Chemical; Thapsigargin	2001
Evidence of a role for cyclic ADP-ribose in calcium signalling and neurotransmitter release in cultured astrocytes. Journal of neurochemistry, 2001, Volume: 78, Issue:3 Topics: Adenosine Diphosphate Ribose; Administration, Topical; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation; Astrocytes; Calcium Signaling; Cell Communication; Cells, Cultured; Coculture Techniques; Connexin 43; Cyclic ADP-Ribose; gamma-Aminobutyric Acid; Glutamic Acid; Glycyrrhetinic Acid; Hippocampus; Immunoblotting; Membrane Glycoproteins; Microscopy, Fluorescence; Models, Neurological; NAD; NAD+ Nucleosidase; Neurons; Neurotransmitter Agents; Rats; Spectrometry, Fluorescence	2001
Kinetic competence of the cADP-ribose-CD38 complex as an intermediate in the CD38/NAD+ glycohydrolase-catalysed reactions: implication for CD38 signalling. The Biochemical journal, 2001, Sep-01, Volume: 358, Issue:Pt 2 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Catalysis; Cattle; Cyclic ADP-Ribose; Kinetics; Macromolecular Substances; Models, Chemical; NAD; NAD+ Nucleosidase; Signal Transduction	2001
A self-restricted CD38-connexin 43 cross-talk affects NAD+ and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblasts. The Journal of biological chemistry, 2001, Dec-21, Volume: 276, Issue:51 Topics: 3T3 Cells; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Base Sequence; Calcium; Connexin 43; Cyclic ADP-Ribose; DNA Primers; Enzyme Activation; Fibroblasts; Membrane Glycoproteins; Mice; NAD; NAD+ Nucleosidase; Phosphorylation; Protein Kinase C	2001
Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo. Nature medicine, 2001, Volume: 7, Issue:11 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium Signaling; Chemotaxis, Leukocyte; Cyclic ADP-Ribose; Lymphoid Tissue; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; NAD; NAD+ Nucleosidase; Neutrophils; Pneumococcal Infections; Ryanodine; Streptococcus pneumoniae	2001
A novel cycling assay for cellular cADP-ribose with nanomolar sensitivity. The Biochemical journal, 2002, Jan-15, Volume: 361, Issue:Pt 2 Topics: Adenosine Diphosphate Ribose; Animals; Calcium Signaling; Cyclic ADP-Ribose; NAD; Rats; Sensitivity and Specificity	2002
CD38 expression and NAD+-induced intracellular Ca+ mobilization in isolated retinal Müller cells. Glia, 2002, Volume: 39, Issue:3 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Ambystoma; Animals; Antigens, CD; Calcium Signaling; Cell Separation; Cyclic ADP-Ribose; Extracellular Space; In Vitro Techniques; Intracellular Fluid; NAD; Retina	2002
High throughput fluorescence-based assays for cyclic ADP-ribose, NAADP, and their metabolic enzymes. Combinatorial chemistry & high throughput screening, 2003, Volume: 6, Issue:4 Topics: ADP-ribosyl Cyclase; Antigens, CD; Calcium Signaling; Cyclic ADP-Ribose; Cyclization; Fluorometry; Glycoside Hydrolases; HL-60 Cells; Humans; N-Glycosyl Hydrolases; NAD; NADP	2003
Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells. The Biochemical journal, 2003, Oct-15, Volume: 375, Issue:Pt 2 Topics: ADP-ribosyl Cyclase; Antibodies, Monoclonal; Calcium; Cell Division; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Humans; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Lipopolysaccharides; Monocytes; N-Glycosyl Hydrolases; NAD; Ryanodine; Second Messenger Systems; Thapsigargin; Time Factors	2003
Aplysia californica mediated cyclisation of novel 3'-modified NAD+ analogues: a role for hydrogen bonding in the recognition of cyclic adenosine 5'-diphosphate ribose. Bioorganic & medicinal chemistry, 2004, Jan-15, Volume: 12, Issue:2 Topics: ADP-ribosyl Cyclase; Animals; Aplysia; Biochemistry; Calcium; Cyclic ADP-Ribose; Cyclization; Hydrogen Bonding; Kinetics; NAD; Ovum; Sea Urchins	2004
Chemotaxis and calcium responses of phagocytes to formyl peptide receptor ligands is differentially regulated by cyclic ADP ribose. Journal of immunology (Baltimore, Md. : 1950), 2004, Feb-01, Volume: 172, Issue:3 Topics: ADP-ribosyl Cyclase; Animals; Calcium Signaling; Cell Line; Cell Migration Inhibition; Cell Movement; Chemotaxis, Leukocyte; Cyclic ADP-Ribose; Humans; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD; Neutrophil Activation; Neutrophils; Receptors, Formyl Peptide	2004
Release of beta-nicotinamide adenine dinucleotide upon stimulation of postganglionic nerve terminals in blood vessels and urinary bladder. The Journal of biological chemistry, 2004, Nov-19, Volume: 279, Issue:47 Topics: Acetaldehyde; Adenine; Adenosine Triphosphate; Adrenergic Agents; Anesthetics, Local; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Dogs; Electrochemistry; Electrophysiology; Female; Guanethidine; Guinea Pigs; Hydrogen-Ion Concentration; Male; Mesenteric Arteries; Mice; Models, Chemical; Muscle, Smooth; NAD; Norepinephrine; omega-Conotoxin GVIA; Oxidopamine; Rabbits; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stress, Mechanical; Temperature; Tetrodotoxin; Time Factors; Urinary Bladder	2004
Concentrative uptake of cyclic ADP-ribose generated by BST-1+ stroma stimulates proliferation of human hematopoietic progenitors. The Journal of biological chemistry, 2005, Feb-18, Volume: 280, Issue:7 Topics: 3T3 Cells; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, CD34; Biological Transport; Calcium; Cell Proliferation; Cells, Cultured; Coculture Techniques; COS Cells; Cyclic ADP-Ribose; Flow Cytometry; GPI-Linked Proteins; Hematopoietic Stem Cells; Humans; Leukocytes, Mononuclear; Membrane Glycoproteins; Mice; NAD; Nucleoside Transport Proteins; Stromal Cells	2005
Production of calcium-mobilizing metabolites by a novel member of the ADP-ribosyl cyclase family expressed in Schistosoma mansoni. Biochemistry, 2005, Aug-23, Volume: 44, Issue:33 Topics: ADP-ribosyl Cyclase; Animals; Aplysia; Base Sequence; Calcium; Calcium Signaling; Cloning, Molecular; Cyclic ADP-Ribose; Gene Expression; Molecular Sequence Data; NAD; NAD+ Nucleosidase; NADP; Phylogeny; Schistosoma mansoni	2005
ADP-ribosyl cyclase and GDP-ribosyl cyclase activities are not always equivalent: impact on the study of the physiological role of cyclic ADP-ribose. Analytical biochemistry, 2005, Nov-15, Volume: 346, Issue:2 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Guanine Nucleotides; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Schistosoma mansoni	2005
Extracellular NAD+ regulates intracellular calcium levels and induces activation of human granulocytes. The Biochemical journal, 2006, Feb-01, Volume: 393, Issue:Pt 3 Topics: ADP-ribosyl Cyclase; Calcium; Chemotaxis; Cyclic ADP-Ribose; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Granulocytes; Humans; NAD; Nitric Oxide; Respiratory Burst; Signal Transduction; Superoxides	2006
The CD38-independent ADP-ribosyl cyclase from mouse brain synaptosomes: a comparative study of neonate and adult brain. The Biochemical journal, 2006, Apr-15, Volume: 395, Issue:2 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Aging; Animals; Animals, Newborn; Brain; Cyclic ADP-Ribose; Guanine Nucleotides; Hydrogen-Ion Concentration; Kinetics; Mice; Mice, Knockout; NAD; Synaptosomes; Zinc	2006
CCL5 evokes calcium signals in microglia through a kinase-, phosphoinositide-, and nucleotide-dependent mechanism. Journal of neuroscience research, 2006, Volume: 83, Issue:8 Topics: Agammaglobulinaemia Tyrosine Kinase; Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Chemokine CCL5; Chemokines, CC; Cyclic ADP-Ribose; Encephalitis; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Immunity, Innate; Immunologic Surveillance; Inositol 1,4,5-Trisphosphate; Janus Kinase 1; Microglia; NAD; Nerve Degeneration; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Receptors, CCR5; Signal Transduction; Type C Phospholipases	2006
CD38 induces apoptosis of a murine pro-B leukemic cell line by a tyrosine kinase-dependent but ADP-ribosyl cyclase- and NAD glycohydrolase-independent mechanism. International immunology, 2006, Volume: 18, Issue:7 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Apoptosis; B-Lymphocytes; Calcium; Calcium Signaling; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclic ADP-Ribose; Enzyme Inhibitors; Hematopoietic Stem Cells; Immunologic Capping; Leukemia, B-Cell; Lymphocyte Activation; Membrane Microdomains; Mice; NAD	2006
Decreased cADPR and increased NAD+ in the Cd38-/- mouse. Biochemical and biophysical research communications, 2006, Jul-21, Volume: 346, Issue:1 Topics: ADP-ribosyl Cyclase 1; Animals; Brain; Cyclic ADP-Ribose; Kidney; Lung; Membrane Glycoproteins; Mice; Mice, Knockout; Myocardium; NAD	2006
Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells: intracellular concentration decrease in NAD and increase in cyclic ADP-ribose. FEBS letters, 2006, Sep-04, Volume: 580, Issue:20 Topics: ADP-ribosyl Cyclase; Animals; Bradykinin; Cell Line, Tumor; Cell Membrane; Cyclic ADP-Ribose; Hybrid Cells; Mice; NAD; Neuroblastoma; Rats; Second Messenger Systems; Vasodilator Agents	2006
Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes. The Journal of biological chemistry, 2006, Oct-20, Volume: 281, Issue:42 Topics: Cell Line, Tumor; Chemotaxis; Cyclic ADP-Ribose; Cyclic AMP; Down-Regulation; Granulocytes; Humans; Inositol 1,4,5-Trisphosphate; NAD; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; RNA, Small Interfering; Transfection	2006
Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis. The Journal of biological chemistry, 2006, Oct-27, Volume: 281, Issue:43 Topics: ADP-ribosyl Cyclase 1; Amino Acid Substitution; Base Sequence; Binding Sites; Catalysis; Cold Temperature; Crystallography, X-Ray; Cyclic ADP-Ribose; Dimerization; Enzyme Stability; Glutamic Acid; Guanosine Diphosphate Sugars; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Molecular; Molecular Sequence Data; NAD; NAD+ Nucleosidase; Sequence Homology, Nucleic Acid; Serine; Static Electricity; Substrate Specificity; Water	2006
Extracellular NAD+ metabolism modulates osteoclastogenesis. Biochemical and biophysical research communications, 2006, Oct-20, Volume: 349, Issue:2 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Animals; Calcium; Cyclic ADP-Ribose; Lymphocytes; Macrophage Colony-Stimulating Factor; Mice; Mice, Inbred C57BL; Models, Biological; NAD; Osteoclasts	2006
Redesign of Schistosoma mansoni NAD+ catabolizing enzyme: active site H103W mutation restores ADP-ribosyl cyclase activity. Biochemistry, 2006, Oct-03, Volume: 45, Issue:39 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Substitution; Animals; Binding Sites; Calcium; Catalysis; Cyclic ADP-Ribose; Helminth Proteins; Humans; Mutation, Missense; NAD; Schistosoma mansoni	2006
Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38. The Journal of biological chemistry, 2007, Feb-23, Volume: 282, Issue:8 Topics: ADP-ribosyl Cyclase 1; Binding Sites; Calcium Signaling; Catalysis; Crystallography, X-Ray; Cyclic ADP-Ribose; Humans; Membrane Glycoproteins; NAD; Protein Structure, Secondary; Protein Structure, Tertiary	2007
Water maze performance in young male Long-Evans rats is inversely affected by dietary intakes of niacin and may be linked to levels of the NAD+ metabolite cADPR. The Journal of nutrition, 2007, Volume: 137, Issue:4 Topics: Animals; Brain; Cyclic ADP-Ribose; Diet; Food Deprivation; Male; Maze Learning; NAD; Niacin; Rats; Rats, Long-Evans; Swimming	2007
Extracellular NAD is a regulator for FcgammaR-mediated phagocytosis in murine macrophages. Biochemical and biophysical research communications, 2008, Feb-29, Volume: 367, Issue:1 Topics: ADP-ribosyl Cyclase 1; Animals; Biological Transport; Calcium; Cells, Cultured; Cyclic ADP-Ribose; Extracellular Space; Immunoglobulin G; Macrophages; Mice; NAD; Phagocytosis; Receptors, IgG	2008
Glucocorticoid regulation of CD38 expression in human airway smooth muscle cells: role of dual specificity phosphatase 1. American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:1 Topics: ADP-ribosyl Cyclase 1; Cells, Cultured; Cyclic ADP-Ribose; Dexamethasone; Dual Specificity Phosphatase 1; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Glucocorticoids; Humans; MAP Kinase Signaling System; Membrane Glycoproteins; Myocytes, Smooth Muscle; NAD; NF-kappa B; Respiratory System; RNA Stability; RNA, Small Interfering; Transcription Factor AP-1; Transcription, Genetic; Tumor Necrosis Factor-alpha	2008
Boric acid inhibits stored Ca2+ release in DU-145 prostate cancer cells. Cell biology and toxicology, 2009, Volume: 25, Issue:4 Topics: ADP-ribosyl Cyclase 1; Boric Acids; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Proliferation; Cyclic ADP-Ribose; Humans; Male; NAD; NADP	2009
Cyclic ADP-ribose links metabolism to multiple fission in the dinoflagellate Crypthecodinium cohnii. Cell calcium, 2009, Volume: 45, Issue:4 Topics: ADP-ribosyl Cyclase; Animals; Calcium; Cell Division; Cell Membrane Permeability; Chelating Agents; Cyclic ADP-Ribose; Dinoflagellida; Glucose; Inosine Nucleotides; Iodoacetates; Ionophores; Models, Biological; NAD; Temperature	2009
Mechanism of cyclizing NAD to cyclic ADP-ribose by ADP-ribosyl cyclase and CD38. The Journal of biological chemistry, 2009, Oct-02, Volume: 284, Issue:40 Topics: ADP-ribosyl Cyclase 1; Animals; Biocatalysis; Calcium; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Cyclic ADP-Ribose; Cyclization; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; Protein Conformation; Protein Engineering; Substrate Specificity	2009
Role of CD38, a cyclic ADP-ribosylcyclase, in morphine antinociception and tolerance. The Journal of pharmacology and experimental therapeutics, 2010, Sep-01, Volume: 334, Issue:3 Topics: ADP-ribosyl Cyclase 1; Analgesics, Opioid; Animals; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Drug Tolerance; Hot Temperature; Hypothermia; Immersion; Injections, Intraventricular; Male; Mice; Mice, Knockout; Morphine; Motor Activity; NAD; Niacinamide; Pain; Pain Measurement; Reaction Time; Ryanodine Receptor Calcium Release Channel	2010
Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel. The Journal of biological chemistry, 2010, Sep-24, Volume: 285, Issue:39 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Humans; Hydrogen Peroxide; NAD; NADP; Oxidants; Oxidative Stress; TRPM Cation Channels; Xenopus laevis	2010
Cyclic ADP-ribose requires CD38 to regulate the release of ATP in visceral smooth muscle. The FEBS journal, 2011, Volume: 278, Issue:17 Topics: Adenosine Triphosphate; ADP-ribosyl Cyclase 1; Animals; Calcium-Transporting ATPases; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Electric Stimulation; Enzyme Inhibitors; Guanine Nucleotides; Guanosine Diphosphate Sugars; In Vitro Techniques; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle, Smooth; NAD; Receptors, Cell Surface; Ryanodine; Spectrometry, Fluorescence; Urinary Bladder	2011
Connexin-43 hemichannels mediate cyclic ADP-ribose generation and its Ca2+-mobilizing activity by NAD+/cyclic ADP-ribose transport. The Journal of biological chemistry, 2011, Dec-30, Volume: 286, Issue:52 Topics: ADP-ribosyl Cyclase 1; Animals; Biological Transport, Active; Calcium; Connexin 43; Cyclic ADP-Ribose; Cyclic AMP-Dependent Protein Kinases; HeLa Cells; Humans; Membrane Glycoproteins; Mice; NAD; Receptors, IgG; Ryanodine Receptor Calcium Release Channel	2011
Identification of a major enzyme for the synthesis and hydrolysis of cyclic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate. Molecular and cellular biochemistry, 2012, Volume: 366, Issue:1-2 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Brain; Chlorocebus aethiops; Cloning, Molecular; Conserved Sequence; COS Cells; Cyclic ADP-Ribose; Evolution, Molecular; GPI-Linked Proteins; Humans; Hydrolysis; Inosine Nucleotides; Kinetics; Molecular Sequence Data; NAD; Organ Specificity; Phylogeny; Recombinant Fusion Proteins; Sequence Analysis, DNA; Xenopus laevis; Xenopus Proteins	2012
NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes. The Journal of biological chemistry, 2012, Jun-15, Volume: 287, Issue:25 Topics: Acrylamides; Calcium; Calcium Signaling; Cell Proliferation; Cyclic ADP-Ribose; Cytokines; Enzyme Inhibitors; Humans; Interleukin-2; Ion Channel Gating; Jurkat Cells; Mitogens; NAD; Nicotinamide Phosphoribosyltransferase; Piperidines; T-Lymphocytes; Thapsigargin; TRPM Cation Channels	2012
Identification of a novel pathway of transforming growth factor-β1 regulation by extracellular NAD+ in mouse macrophages: in vitro and in silico studies. The Journal of biological chemistry, 2012, Sep-07, Volume: 287, Issue:37 Topics: Animals; Calcium; Calcium Ionophores; Cell Line; Cyclic ADP-Ribose; Macrophages; Mice; Mice, Mutant Strains; Models, Biological; NAD; Toll-Like Receptor 4; Transforming Growth Factor beta1	2012
Determination of ADP-ribosyl cyclase activity, cyclic ADP-ribose, and nicotinic acid adenine dinucleotide phosphate in tissue extracts. Methods in molecular biology (Clifton, N.J.), 2013, Volume: 1016 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Fluorescence; Guanine Nucleotides; Humans; NAD; NAD+ Nucleosidase; NADP; Substrate Cycling; Tissue Extracts	2013
Cycling assay for determining intracellular cyclic adp-ribose levels. Cold Spring Harbor protocols, 2013, Jun-01, Volume: 2013, Issue:6 Topics: ADP-ribosyl Cyclase; Alcohol Dehydrogenase; Cyclic ADP-Ribose; Cytoplasm; Ethanol; NAD; NADH Dehydrogenase; Niacinamide; Oxazines; Xanthenes	2013
Measuring CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) activity by reverse-phase HPLC. Cold Spring Harbor protocols, 2013, Jun-01, Volume: 2013, Issue:6 Topics: ADP-ribosyl Cyclase 1; Animals; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Cytological Techniques; Humans; NAD	2013
CD38 mediates the intracellular ATP levels and cell survival of C6 glioma cells. Neuroreport, 2014, May-28, Volume: 25, Issue:8 Topics: Adenosine Triphosphate; ADP-ribosyl Cyclase 1; Animals; Cell Line, Tumor; Cell Survival; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Extracellular Fluid; Glioma; L-Lactate Dehydrogenase; Mice; NAD; RNA Interference; RNA, Small Interfering	2014
[Influence exogenous nicotinamide adenine dinucleotide (NAD+) on contractile and bioelectric activity of the rat heart]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2014, Volume: 100, Issue:4 Topics: Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic ADP-Ribose; Male; Myocardial Contraction; Myocardium; NAD; Rats; Receptors, Purinergic P2X; Receptors, Purinergic P2Y	2014
NQO1-induced activation of AMPK contributes to cancer cell death by oxygen-glucose deprivation. Scientific reports, 2015, Jan-14, Volume: 5 Topics: ADP-ribosyl Cyclase 1; AMP-Activated Protein Kinases; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Cell Line, Tumor; Cyclic ADP-Ribose; Enzyme Activation; Glucose; Humans; Mice; Models, Biological; NAD; NAD(P)H Dehydrogenase (Quinone); Neoplasms; Oxygen; Phosphorylation; RNA, Small Interfering	2015
Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility. PloS one, 2015, Volume: 10, Issue:8 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Cyclic ADP-Ribose; Diet, Western; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; NAD; Oxidation-Reduction; Physical Conditioning, Animal	2015
Porcine CD38 exhibits prominent secondary NAD(+) cyclase activity. Protein science : a publication of the Protein Society, 2016, Volume: 25, Issue:3 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Crystallography, X-Ray; Cyclic ADP-Ribose; Humans; Models, Molecular; NAD; Protein Domains; Swine	2016
Blocking NAD(+)/CD38/cADPR/Ca(2+) pathway in sepsis prevents organ damage. The Journal of surgical research, 2016, Volume: 201, Issue:2 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Malondialdehyde; Membrane Glycoproteins; Multiple Organ Failure; NAD; Random Allocation; Rats, Sprague-Dawley; Sepsis; Superoxide Dismutase	2016
mTORC1 and SIRT1 Cooperate to Foster Expansion of Gut Adult Stem Cells during Calorie Restriction. Cell, 2016, Jul-14, Volume: 166, Issue:2 Topics: Adult Stem Cells; Animals; Caloric Restriction; Cell Proliferation; Cyclic ADP-Ribose; Diet; Intestinal Mucosa; Intestines; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Multiprotein Complexes; NAD; Organoids; Phosphorylation; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Sirtuin 1; Sirtuin 2; TOR Serine-Threonine Kinases	2016
TIR domains of plant immune receptors are NAD Science (New York, N.Y.), 2019, 08-23, Volume: 365, Issue:6455 Topics: Amino Acid Substitution; Arabidopsis; Arabidopsis Proteins; Armadillo Domain Proteins; Biomarkers; Catalytic Domain; Cell Death; Conserved Sequence; Cyclic ADP-Ribose; Cytoskeletal Proteins; DNA-Binding Proteins; Glutamic Acid; Host-Pathogen Interactions; NAD; NAD+ Nucleosidase; Receptors, Immunologic	2019
Imeglimin amplifies glucose-stimulated insulin release from diabetic islets via a distinct mechanism of action. PloS one, 2021, Volume: 16, Issue:2 Topics: Adenosine Triphosphate; Animals; Calcium; Cyclic ADP-Ribose; Cytokines; Diabetes Mellitus, Type 2; Glucose; Insulin Secretion; Islets of Langerhans; Male; Models, Biological; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Rats, Wistar; Ryanodine Receptor Calcium Release Channel; Sulfonylurea Compounds; Triazines	2021
Okamoto model for necrosis and its expansions, CD38-cyclic ADP-ribose signal system for intracellular Ca Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2021, Volume: 97, Issue:8 Topics: Animals; Cyclic ADP-Ribose; DNA; Islets of Langerhans; NAD; Necrosis; Poly(ADP-ribose) Polymerase Inhibitors; Proinsulin	2021
Antiviral activity of bacterial TIR domains via immune signalling molecules. Nature, 2021, Volume: 600, Issue:7887 Topics: Bacillus; Bacterial Proteins; Bacteriophages; Cyclic ADP-Ribose; Evolution, Molecular; Models, Molecular; NAD; Protein Domains; Receptors, Interleukin-1; Signal Transduction; Substrate Specificity; Toll-Like Receptors	2021
Products of gut microbial Toll/interleukin-1 receptor domain NADase activities in gnotobiotic mice and Bangladeshi children with malnutrition. Cell reports, 2022, 04-26, Volume: 39, Issue:4 Topics: Animals; Bacteria; Child; Cyclic ADP-Ribose; Gastrointestinal Microbiome; Germ-Free Life; Humans; Malnutrition; Mice; NAD; NAD+ Nucleosidase; Receptors, Interleukin-1	2022
Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science (New York, N.Y.), 2022, 09-30, Volume: 377, Issue:6614 Topics: Adaptor Proteins, Vesicular Transport; ADP-ribosyl Cyclase; Bacteria; Bacterial Proteins; Cyclic ADP-Ribose; Isomerism; NAD; Plant Immunity; Protein Domains; Receptors, Interleukin-1; Signal Transduction; Toll-Like Receptors; Tryptophan	2022
Synthesis and biological evaluation of novel photo-clickable adenosine and cyclic ADP-ribose analogs: 8-N Bioorganic & medicinal chemistry, 2022, 12-15, Volume: 76 Topics: Adenosine; Cyclic ADP-Ribose; Humans; NAD	2022
Remission of social behavior impairment by oral administration of a precursor of NAD in CD157, but not in CD38, knockout mice. Frontiers in immunology, 2023, Volume: 14 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Cyclic ADP-Ribose; Male; Mice; Mice, Knockout; NAD; Social Behavior	2023
TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion. The EMBO journal, 2006, May-03, Volume: 25, Issue:9 Topics: Animals; Body Temperature; Calcium; Cells, Cultured; Cyclic ADP-Ribose; Hot Temperature; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Rats; RNA, Small Interfering; TRPM Cation Channels	2006