nad has been researched along with beta-lapachone in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Boothman, DA; Pink, JJ; Planchon, SM; Siegel, D; Tagliarino, C; Varnes, ME | 1 |
| Chau, YP; Lin, SY; Liu, TJ | 1 |
| Bentle, MS; Bey, EA; Boothman, DA; Reinicke, KE; Spitz, DR | 1 |
| Choi, HS; Chung, J; Han, J; Hwang, JH; Jang, C; Jo, EJ; Jo, YS; Kho, YL; Kim, DW; Kim, JM; Kim, YK; Kwak, TH; Kweon, GR; Kyung, T; Lee, I; Lee, SH; Park, JH; Park, MK; Shong, M; Yoo, SK | 1 |
| Gang, GT; Hwang, JH; Kim, DH; Kim, YH; Kwak, TH; Lee, CH; Lee, IK; Noh, JR; Shong, M; Son, HY | 1 |
| Bair, JS; Bey, EA; Boothman, DA; Dong, Y; Gao, J; Hergenrother, PJ; Huang, X; Kilgore, JA; Li, LS; Parkinson, EI; Patel, M; Wang, Y; Williams, NS | 1 |
| Kim, D; Kim, JH; Kim, JM; Kwak, TH; Lee, CH; Lee, D; Lee, JS; Lee, SH; Lee, SJ; Park, AH; Yang, SJ; Yeom, YI | 1 |
| Choe, SK; Choi, JH; Jo, HJ; Karna, A; Kim, HJ; Kwak, TH; Lee, CH; Lee, SH; Oh, GS; Park, R; Shen, A; So, HS; Yang, SH | 1 |
| Choi, HS; Gang, GT; Hwang, JH; Jeong, KH; Kim, KS; Kim, YH; Kwak, TH; Lee, CH; Lee, IK; Noh, JR; Oh, WK | 1 |
| Jeong, MH; Kim, JH; Kwak, TH; Park, WJ; Seo, KS | 1 |
| Cheng, XF; Hao, HP; Li, QR; Liu, HY; Wang, GJ | 1 |
| Gu, DR; Kim, HJ; Kim, MS; Lee, JN; Lee, SH; Oh, GS | 1 |
| Chau, YP; Don, MJ; Kung, HN; Lai, SM; Lin, SY; Lo, YT; Shy, HT; Syu, JP | 1 |
| Gong, Q; Hu, J; Li, T; Li, X; Wu, X; Yang, F; Zhang, X | 1 |
| Dringen, R; Watermann, P | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
16 other study(ies) available for nad and beta-lapachone
| Article | Year |
|---|---|
NAD(P)H:Quinone oxidoreductase activity is the principal determinant of beta-lapachone cytotoxicity.
Topics: Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Division; Cytochrome Reductases; Cytochrome-B(5) Reductase; Dicumarol; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; Humans; Models, Biological; NAD; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Naphthoquinones; Proteins; Quinone Reductases; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vitamin K | 2000 |
Inhibition of poly(ADP-ribose) polymerase activation attenuates beta-lapachone-induced necrotic cell death in human osteosarcoma cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Bone Neoplasms; Cell Cycle; Cytochrome c Group; DNA Damage; DNA Fragmentation; Enzyme Activation; Flow Cytometry; Genes, p53; Humans; In Situ Nick-End Labeling; Membrane Potentials; NAD; Naphthoquinones; Osteosarcoma; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured | 2002 |
Calcium-dependent modulation of poly(ADP-ribose) polymerase-1 alters cellular metabolism and DNA repair.
Topics: Adenosine Triphosphate; Calcium; Cell Death; Chelating Agents; DNA; DNA Damage; DNA Repair; Egtazic Acid; Enzyme Activation; Humans; Hydrogen Peroxide; NAD; Naphthoquinones; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Time Factors | 2006 |
Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice.
Topics: Adenylate Kinase; Animals; Disease Models, Animal; Energy Metabolism; Metabolic Syndrome; Mice; Mice, Knockout; NAD; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Naphthoquinones; Obesity; Oxidation-Reduction; Phenotype; Signal Transduction | 2009 |
Activation of NAD(P)H:quinone oxidoreductase ameliorates spontaneous hypertension in an animal model via modulation of eNOS activity.
Topics: Acetylcholine; AMP-Activated Protein Kinases; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Humans; Hypertension; Male; Mice; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; RNA Interference; Time Factors; Transfection; Vasodilation; Vasodilator Agents | 2011 |
An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Calcium; Cell Line, Tumor; DNA Damage; Egtazic Acid; Humans; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Necrosis; Neoplasms; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Quinones; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering | 2012 |
Beta-lapachone, a modulator of NAD metabolism, prevents health declines in aged mice.
Topics: Aging; Animals; Behavior, Animal; Body Weight; Caloric Restriction; Cognition; Dietary Supplements; Energy Metabolism; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mitochondria; Muscle, Skeletal; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones | 2012 |
Pharmacological activation of NQO1 increases NAD⁺ levels and attenuates cisplatin-mediated acute kidney injury in mice.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Cisplatin; Mice, Inbred C57BL; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Sirtuin 1; Transcription Factor RelA | 2014 |
Enhanced activation of NAD(P)H: quinone oxidoreductase 1 attenuates spontaneous hypertension by improvement of endothelial nitric oxide synthase coupling via tumor suppressor kinase liver kinase B1/adenosine 5'-monophosphate-activated protein kinase-media
Topics: AMP-Activated Protein Kinases; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cell Line; Cells, Cultured; Endothelial Cells; Enzyme Activation; GTP Cyclohydrolase; Humans; Hypertension; Male; Mice; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Nitric Oxide Synthase Type III; Protein Serine-Threonine Kinases; Rats; Rats, Inbred SHR; Sirtuin 1; Vasodilation | 2014 |
β-Lapachone attenuates mitochondrial dysfunction in MELAS cybrid cells.
Topics: DNA, Mitochondrial; Energy Metabolism; Gene Expression Regulation; HeLa Cells; Humans; Lactic Acid; MELAS Syndrome; Membrane Potential, Mitochondrial; Mitochondria; NAD; Naphthoquinones; Reactive Oxygen Species | 2014 |
NAMPT inhibition synergizes with NQO1-targeting agents in inducing apoptotic cell death in non-small cell lung cancer cells.
Topics: Abietanes; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytokines; Enzyme Inhibitors; Humans; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Nicotinamide Phosphoribosyltransferase | 2016 |
The inhibitory effect of beta-lapachone on RANKL-induced osteoclastogenesis.
Topics: AMP-Activated Protein Kinases; Animals; Bone Diseases; Cell Differentiation; Cell Survival; Gene Expression Profiling; Mice; Mice, Inbred C57BL; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Proto-Oncogene Proteins c-fos; RANK Ligand; Real-Time Polymerase Chain Reaction | 2017 |
Mitochondrial activity is the key to the protective effect of β-Lapachone, a NAD
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cisplatin; Female; Humans; Mitochondria; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones | 2022 |
A Carbon-Carbon Bond Cleavage-Based Prodrug Activation Strategy Applied to β-Lapachone for Cancer-Specific Targeting.
Topics: Antineoplastic Agents; Biological Products; Carbon; Cell Line, Tumor; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Neoplasms; Prodrugs; Reactive Oxygen Species | 2022 |
β-lapachone-mediated WST1 Reduction as Indicator for the Cytosolic Redox Metabolism of Cultured Primary Astrocytes.
Topics: Astrocytes; Formazans; Glucose; NAD; NAD(P)H Dehydrogenase (Quinone); NADP; Naphthoquinones; Oxidation-Reduction; Water | 2023 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |