Page last updated: 2024-08-17

nad and benzamide

nad has been researched along with benzamide in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199011 (32.35)18.7374
1990's14 (41.18)18.2507
2000's7 (20.59)29.6817
2010's2 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aneiro, L; Aune, T; Korn, JH; Nuveen, E; Piela-Smith, TH1
Banasik, M; Komura, H; Shimoyama, M; Ueda, K1
Gasparini, A; Guida, L; Polvani, C; Suzuki, H; Zocchi, E1
Althaus, FR; Kleczkowska, HE; Szumiel, I1
Guida, L; Polvani, C; Zocchi, E1
Delfs, T; Wielckens, K1
Hilz, H; Janssen, OE1
Benjamin, RC; Jacobson, EL; Jacobson, MK; Moss, J; Rankin, PW1
Nakanishi, S; Uyeki, EM1
Dietrich, A; Grahn, H; Grätz, R; Kröger, H1
Dritschilo, A; Kasid, UN; Lubet, RA; Smulson, ME; Stefanik, DF1
Johanson, KJ; Szumiel, I; Wlodek, D1
Jacobson, EL; Jacobson, MK; Jonsson, GG1
Berger, NA; Berger, SJ; Sims, JL1
Nakanishi, S; Nishio, A; Uyeki, EM1
George, E; Hilz, H; Pless, T; Wielckens, K1
Aboul-Ela, N; Hanson, K; Jacobson, MK; Wu, MC1
Cherney, B; Ding, R; Istock, N; Smulson, M1
Farber, JL; Tsukidate, K; Yamamoto, K1
Bao, J; Dawson, TM; Dawson, VL; Eliasson, MJ; Hurn, PD; Mandir, AS; Pieper, A; Sampei, K; Snyder, SH; Traystman, RJ; Wang, ZQ1
Browning, JC; Davis, RE; Hsieh, JC; Katsikis, PD; Lu, QA; Mysore, V1
Cosi, C; Marien, M3
Banasik, M; Ueda, K1
Cheung, A; Zhang, J1
Chen, Y; Sevigny, MB; Swanson, RA; Ying, W1
Chiarugi, A1
Cosi, C; Guerin, K; Koek, W; Marien, M; Rollet, K1
Bhattacharyya, NP; Ghosh, U1
Banaszewska, M; Konat, GW1
Chuang, MC; Huang, CC; Lin, CH; Lin, P; Lin, PH1
Feng, X; Koh, DW; Zhou, Y1
Elboray, EE; Iida, T; Itoh, Y; Kitao, Y; Kotoku, M; Kurohara, T; Li, Y; Mellini, P; Miura, Y; Miyake, Y; Suzuki, M; Suzuki, T; Takahashi, Y; Tojo, T; Tsumoto, H1

Other Studies

34 other study(ies) available for nad and benzamide

ArticleYear
Impairment of lymphocyte adhesion to cultured fibroblasts and endothelial cells by gamma-irradiation.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Jan-01, Volume: 148, Issue:1

    Topics: Adenosine Triphosphate; Benzamides; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Endothelium, Vascular; Fibroblasts; Gamma Rays; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-1; Lymphocyte Function-Associated Antigen-1; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Recombinant Proteins; T-Lymphocytes

1992
Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase.
    The Journal of biological chemistry, 1992, Jan-25, Volume: 267, Issue:3

    Topics: Acetophenones; ADP Ribose Transferases; Animals; Benzamides; Cattle; Enzyme Inhibitors; Fatty Acids, Nonesterified; Isoquinolines; Kinetics; NAD; Naphthalenes; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Pyrimidines; Quinazolines; Quinolines; Structure-Activity Relationship; Thymus Gland

1992
Glyoxylic acid promotes poly(ADP-ribosyl)ation of nuclear proteins in K562 cells cultured at limiting dilution.
    Biochemistry international, 1990, Volume: 22, Issue:2

    Topics: Benzamides; Glycolates; Glyoxylates; Humans; Immunoenzyme Techniques; Leukemia, Erythroblastic, Acute; NAD; Nuclear Proteins; Poly Adenosine Diphosphate Ribose; Tumor Cells, Cultured

1990
Adaptive changes in NAD+ metabolism in ultraviolet light-irradiated murine lymphoma cells.
    Cell biology and toxicology, 1990, Volume: 6, Issue:3

    Topics: Adaptation, Physiological; Adenosine Diphosphate Ribose; Animals; Benzamides; Cell Count; DNA Damage; Lymphoma; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured; Ultraviolet Rays

1990
Glyoxylic acid prevents NAD+ and NADH depletion in K562 cells cultured at limiting dilution.
    Biochemical and biophysical research communications, 1990, Nov-30, Volume: 173, Issue:1

    Topics: Adenosine; Benzamides; Cell Line; Chromatography, High Pressure Liquid; Glyoxylates; Humans; Kinetics; Leukemia, Erythroblastic, Acute; NAD; Oxidation-Reduction

1990
Glucocorticoid-induced cell death and poly[adenosine diphosphate(ADP)-ribosyl]ation: increased toxicity of dexamethasone on mouse S49.1 lymphoma cells with the poly(ADP-ribosyl)ation inhibitor benzamide.
    Endocrinology, 1986, Volume: 119, Issue:5

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Line; Cell Survival; Dexamethasone; DNA Repair; DNA Replication; Drug Synergism; Lymphoma; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Protein Biosynthesis; RNA

1986
Differentiation of 3T3-L1 pre-adipocytes induced by inhibitors of poly(ADP-ribose) polymerase and by related noninhibitory acids.
    European journal of biochemistry, 1989, Apr-01, Volume: 180, Issue:3

    Topics: Adenosine Diphosphate Ribose; Adipose Tissue; ADP Ribose Transferases; Animals; Benzamides; Benzoates; Benzoic Acid; Cell Differentiation; Cell Line; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation; Glycerolphosphate Dehydrogenase; High Mobility Group Proteins; Insulin; Mice; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

1989
Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo.
    The Journal of biological chemistry, 1989, Mar-15, Volume: 264, Issue:8

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Benzamides; Bromodeoxyuridine; Cattle; NAD; NAD+ Nucleosidase; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors

1989
Benzamide on chondrocytic differentiation in chick limb bud cell culture.
    Journal of embryology and experimental morphology, 1985, Volume: 85

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cartilage; Cell Differentiation; Cells, Cultured; Chickens; DNA; Foot; Hindlimb; NAD; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Proteoglycans; RNA; Wings, Animal

1985
Influence of oxypangam upon the induction of tyrosine aminotransferase, the NAD content and the ADPR transferase activity in several organs of the rat.
    General pharmacology, 1987, Volume: 18, Issue:1

    Topics: Animals; Benzamides; Enzyme Induction; Liver; NAD; Poly(ADP-ribose) Polymerases; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Tyrosine Transaminase

1987
Relationship between DNA strand breaks and inhibition of poly (ADP-ribosylation): enhancement of carcinogen-induced transformation.
    Carcinogenesis, 1986, Volume: 7, Issue:2

    Topics: Animals; Base Sequence; Benzamides; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA, Neoplasm; Methylnitronitrosoguanidine; Mice; NAD; Oncogenes; Poly(ADP-ribose) Polymerase Inhibitors

1986
Differential effect of benzamide on NAD+ content and the frequency of chromatid aberrations in X-irradiated L5178Y-R and L5178Y-S cells.
    Acta oncologica (Stockholm, Sweden), 1988, Volume: 27, Issue:6b

    Topics: Animals; Benzamides; Cell Survival; Chromosome Aberrations; DNA Repair; Lymphoma; Mice; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured

1988
Mechanism of alteration of poly(adenosine diphosphate-ribose) metabolism by hyperthermia.
    Cancer research, 1988, Aug-01, Volume: 48, Issue:15

    Topics: Adenosine Triphosphate; Animals; Benzamides; Fever; Glycoside Hydrolases; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose

1988
Poly(ADP-ribose) Polymerase inhibitors preserve nicotinamide adenine dinucleotide and adenosine 5'-triphosphate pools in DNA-damaged cells: mechanism of stimulation of unscheduled DNA synthesis.
    Biochemistry, 1983, Oct-25, Volume: 22, Issue:22

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cells, Cultured; DNA; DNA Repair; DNA, Neoplasm; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; NAD+ Nucleosidase; Neoplasm Proteins; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; RNA, Neoplasm

1983
Effect of benzamide on cell growth, NAD and ATP levels in cultured chick limb bud cells.
    Biochemical and biophysical research communications, 1984, Jun-15, Volume: 121, Issue:2

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cartilage; Cell Division; Cells, Cultured; Chick Embryo; DNA; NAD; Poly(ADP-ribose) Polymerases

1984
Stimulation of poly(ADP-ribosyl)ation during Ehrlich ascites tumor cell "starvation" and suppression of concomitant DNA fragmentation by benzamide.
    The Journal of biological chemistry, 1983, Apr-10, Volume: 258, Issue:7

    Topics: Animals; Benzamides; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Kinetics; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose

1983
Evidence for unusual stability of ADP-ribosyl linkage to membrane proteins of a murine leukemic cell line.
    Archives of biochemistry and biophysics, 1993, Volume: 302, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Benzamides; Cell Differentiation; Chromatography, Gel; Drug Stability; Granulocyte Colony-Stimulating Factor; Granulocytes; Leukemia, Experimental; Membrane Proteins; Mice; NAD; Recombinant Proteins; Tumor Cells, Cultured

1993
Deletion mutants of poly(ADP-ribose) polymerase support a model of cyclic association and dissociation of enzyme from DNA ends during DNA repair.
    Biochemistry, 1994, May-24, Volume: 33, Issue:20

    Topics: Benzamides; Binding Sites; DNA; DNA Repair; DNA, Circular; Gene Deletion; Gene Expression; HeLa Cells; Humans; Mutagenesis; NAD; Plasmids; Poly(ADP-ribose) Polymerases; Recombinant Proteins; RNA, Antisense; Structure-Activity Relationship; Transfection

1994
Differing effects of the inhibition of poly(ADP-ribose) polymerase on the course of oxidative cell injury in hepatocytes and fibroblasts.
    Biochemical pharmacology, 1993, Aug-03, Volume: 46, Issue:3

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Death; Cells, Cultured; DNA Damage; DNA, Single-Stranded; Hydrogen Peroxide; L Cells; Liver; Male; Mice; NAD; Oxidation-Reduction; Peroxides; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Time Factors

1993
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
    Nature medicine, 1997, Volume: 3, Issue:10

    Topics: Adenosine Triphosphate; Animals; Benzamides; Brain; Cells, Cultured; Cerebral Cortex; Cerebrovascular Circulation; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Hemodynamics; Immunity, Innate; Ischemic Attack, Transient; Isoquinolines; Mice; Mice, Knockout; N-Methylaspartate; NAD; Neurons; Neurotoxins; Nitrates; Nitric Oxide; Piperidines; Poly(ADP-ribose) Polymerases

1997
In situ staining for poly(ADP-ribose) polymerase activity using an NAD analogue.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1998, Volume: 46, Issue:11

    Topics: Animals; Benzamides; Brain; Bromodeoxyuridine; Cell Line; Humans; Immunoenzyme Techniques; Methylnitronitrosoguanidine; Mice; NAD; Nitroprusside; Poly(ADP-ribose) Polymerases; Pyrogallol; Rats; Staining and Labeling; Ultraviolet Rays

1998
Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP): prevention by the poly(ADP-ribose) polymerase inhibitor, benzamide.
    Brain research, 1998, Oct-26, Volume: 809, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzamides; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Frontal Lobe; Male; Mesencephalon; Mice; Mice, Inbred C57BL; NAD; Neuroprotective Agents; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Pyridinium Compounds

1998
Dual inhibitory effects of dimethyl sulfoxide on poly(ADP-ribose) synthetase.
    Journal of enzyme inhibition, 1999, Volume: 14, Issue:3

    Topics: Benzamides; Dimethyl Sulfoxide; Ethanol; Methanol; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Solubility; Solvents; Water

1999
Implication of poly (ADP-ribose) polymerase (PARP) in neurodegeneration and brain energy metabolism. Decreases in mouse brain NAD+ and ATP caused by MPTP are prevented by the PARP inhibitor benzamide.
    Annals of the New York Academy of Sciences, 1999, Volume: 890

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Benzamides; Brain; Corpus Striatum; Dopamine; Dopamine Agents; Frontal Lobe; Male; Mesencephalon; Mice; Mice, Inbred C57BL; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

1999
Central noradrenergic neurotoxicity of DSP4 in mice. Studies on the neuroprotective potential of the poly(ADP-ribose) polymerase inhibitor, benzamide.
    Annals of the New York Academy of Sciences, 1999, Volume: 890

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzamides; Benzylamines; Frontal Lobe; Mice; Mice, Inbred C57BL; NAD; Neurotoxins; Norepinephrine; Poly(ADP-ribose) Polymerase Inhibitors

1999
A scintillation proximity assay for poly(ADP-ribose) polymerase.
    Analytical biochemistry, 2000, Jun-15, Volume: 282, Issue:1

    Topics: Animals; Autoradiography; Benzamides; Biotinylation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunoblotting; Inhibitory Concentration 50; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Scintillation Counting; Time Factors

2000
Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Oct-09, Volume: 98, Issue:21

    Topics: Animals; Astrocytes; Benzamides; Cell Death; Cells, Cultured; Coculture Techniques; Enzyme Inhibitors; Glycoside Hydrolases; Hydrogen Peroxide; Hydrolyzable Tannins; Mice; N-Methylaspartate; NAD; Neurons; Neurotoxins; Oxidants; Oxidative Stress; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, N-Methyl-D-Aspartate; Tannins

2001
Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in rats.
    British journal of pharmacology, 2002, Volume: 137, Issue:6

    Topics: Adenosine Triphosphate; Animals; Benzamides; Benzoic Acid; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Interferon-gamma; Interleukin-2; Lymph Nodes; Lymphocytes; NAD; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Lew; RNA, Messenger; Spinal Cord; Time Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha

2002
The PARP inhibitor benzamide protects against kainate and NMDA but not AMPA lesioning of the mouse striatum in vivo.
    Brain research, 2004, Jan-16, Volume: 996, Issue:1

    Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Brain Injuries; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Time Factors

2004
Benzamide and 4-amino 1,8 naphthalimide treatment inhibit telomerase activity by down-regulating the expression of telomerase associated protein and inhibiting the poly(ADP-ribosyl)ation of telomerase reverse transcriptase in cultured cells.
    The FEBS journal, 2005, Volume: 272, Issue:16

    Topics: 1-Naphthylamine; Benzamides; Blotting, Western; Cells, Cultured; DNA-Binding Proteins; Down-Regulation; Enzyme Inhibitors; Humans; Immunoprecipitation; K562 Cells; NAD; Naphthalimides; Poly Adenosine Diphosphate Ribose; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Telomerase

2005
Nucleotides induce higher order chromatin degradation.
    Molecular and cellular biochemistry, 2006, Volume: 282, Issue:1-2

    Topics: Animals; Apoptosis; Benzamides; Calcium; Cell Line, Tumor; Cell Nucleus; Chromatin; Chromatin Assembly and Disassembly; Hydrogen Peroxide; NAD; Nucleotides; Poly(ADP-ribose) Polymerases; Rats

2006
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
    Toxicology letters, 2007, Volume: 172, Issue:3

    Topics: Benzamides; Benzoflavones; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Survival; Coumarins; DNA Breaks; Environmental Pollutants; Estrogen Receptor alpha; Glutathione; Humans; NAD; NADP; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Tamoxifen

2007
Activation of cell death mediated by apoptosis-inducing factor due to the absence of poly(ADP-ribose) glycohydrolase.
    Biochemistry, 2011, Apr-12, Volume: 50, Issue:14

    Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Benzamides; Caspase 3; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Radiation; Embryonic Stem Cells; Glycoside Hydrolases; Immunoblotting; Mice; Mice, Knockout; Microscopy, Confocal; Mitochondria; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Transport; Signal Transduction; Trophoblasts; Ultraviolet Rays

2011
Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD
    Journal of medicinal chemistry, 2019, 06-27, Volume: 62, Issue:12

    Topics: Benzamides; Binding Sites; Diketopiperazines; Enzyme Inhibitors; Humans; MCF-7 Cells; Molecular Docking Simulation; NAD; Protein Conformation; Sirtuin 1; Sirtuin 2; Structure-Activity Relationship; Substrate Specificity

2019