Page last updated: 2024-08-17

nad and aspartic acid

nad has been researched along with aspartic acid in 250 studies

Research

Studies (250)

TimeframeStudies, this research(%)All Research%
pre-1990139 (55.60)18.7374
1990's33 (13.20)18.2507
2000's41 (16.40)29.6817
2010's23 (9.20)24.3611
2020's14 (5.60)2.80

Authors

AuthorsStudies
Colman, RF; Ramachandran, N1
Faulkner, A; Jones, CT1
Viale, RO; Williamson, JR1
Chen, JL; Tritz, GJ1
Bremer, J; Davis, EJ1
Johnson, RM; Yeh, YY1
Cederbaum, AI; Rubin, E3
Brody, S; Schmit, JC1
Safer, B1
Greenhouse, WV; Lehninger, AL2
Buniatian, GKh2
Clark, JB; Walsh, JM1
Chen, J; Tritz, GJ1
Dynnik, VV; Ovchinnikov, IA; Sel'kov, EE1
Bartoli, GM; Dani, A; Galeotti, T1
De Liberali, E; Eboli, ML; Galeotti, T; López-Alarcón, L; Palombini, G1
Cronholm, T1
Casciaro, A; Chiaretti, B; Eboli, ML; Galeotti, T; Minotti, G1
Bookelman, H; Janssen, AJ; Sengers, RC; Stadhouders, AM; Trijbels, JM; Veerkamp, JH1
Berdanier, CD; Caton, C; DeVore, V; Ecklund, RE; Tobin, RB1
Gibson, J; Ihlenfeldt, MJ1
Hindfelt, B1
Chandler, JL; Gholson, RK; Griffith, GR1
Matsuno, T2
Berry, MN; Gregory, RB; Phillips, JW1
Berry, MN; Grivell, AR; Phillips, JW1
Berry, MN; Gregory, RB; Grivell, AR; Phillips, JW; Wallace, PG1
Doré, JF; Goetsch, L; Hamedi-Sangsari, F; Malley, S; Navarro, C; Thomasset, N; Tournaire, R; Vila, J1
Bray, T; Grimshaw, CE; Hoch, J; Matthews, DA; Skinner, M; Varughese, KI; Whiteley, JM; Xuong, NH1
Chang, SH; Chen, Z; Lee, WR1
Bray, T; Hoch, J; Matthews, DA; Schneider, M; Skinner, M; Trach, K; Varughese, KI; Whiteley, JM; Xuong, NH1
Korpela, T; Kurkijärvi, K; Vierijoki, T1
Aksamit, RR; Backlund, PS; Cantoni, GL; Date, T; Fujioka, M; Gomi, T; Takata, Y1
Collier, RJ; Reich, KA; Weinstein, BR; Wilson, BA1
Fan, F; Lorenzen, JA; Plapp, BV1
Darnay, BG; Rodwell, VW; Wang, Y1
Handler, JA; Kizaki, Z; Sugano, T; Thurman, RG; Yoshihara, H1
Greenberg, JH; Karp, A; Reivich, M; Uematsu, D1
Colman, RF; Huang, YC1
Barbieri, JT; Collier, RJ; Tweten, RK1
Chagoya de Sánchez, V; Díaz-Muñoz, M; Hernández-Muñoz, R1
Berdanier, CD; Deaver, OE; McCusker, RH; Wander, RC1
Ivanova, V; Tomova, N1
Bloxham, DP; Handford, PA; Ner, SS; Wilton, DC1
Kauppinen, RA; Nicholls, DG; Sihra, TS1
Tomasiak, M1
Eboli, ML; López-Alarcón, L1
De Zwaan, A; Putzer, V1
Choules, GL; Yarrison, G; Young, DW1
Even, HL; Roon, RJ1
Hatch, MD; Kagawa, T1
Brosnan, JT; Williamson, DH1
Cohen, GN; Truffa-Bachi, P; Veron, M1
Fritz, PJ1
Ahmad, F; Moat, AG1
Isquith, AJ; Moat, AG1
Katunuma, N; Matsuzawa, T1
Gascoyne, T; Krebs, HA; Notton, BM1
Din, GA; Lees, H; Suzuki, I1
Hoberman, HD; Prosky, L1
Katsuki, H; Murai, T; Nagai, J; Takeo, K1
Bloch-Frankenthal, L; Melnik, Y1
Meyer, E; Wurtz, B1
Katz, J; Schmidt, K1
Bressler, R; Ruderman, N; Shafrir, E1
Meister, A; Tate, SS1
Kojima, Y; Wacker, WE1
Arnaud, M; Johnson, C; Nordmann, J; Nordmann, R1
Nordmann, J; Nordmann, R1
LaNoue, K; Nicklas, WJ; Williamson, JR1
Davis, EJ; Lumeng, L2
Sanwal, BD1
Anderson, J; Blank, W; Niklas, W; Williamson, JR1
Brosnan, JT; Krebs, HA; Williamson, DH1
Chandler, JL; Gholson, RK; Scott, TA1
LaNoue, KF; Williamson, JR1
Scrutton, MC1
Joy, KW; Pahlich, E1
Heck, HA; Truffa-Bachi, P1
Ellison, JS; Siegel, L1
Ballard, FJ1
Gutfreund, H1
Ziegler, K1
Ogur, M; Ulane, R1
Cheng, SC1
Chandler, JL; Gholson, RK2
Häkkinen, HM; Kulonen, E1
Garber, AJ; Hanson, RW1
Blattmann, P; Rétey, J1
Beattie, DS; Cederbaum, AI; Lieber, CS; Rubin, E1
MacLeod, RA; Rogers, HJ; Thurman, P1
Chandler, JL; Tritz, GJ1
Iskushev, VS; Lifshits, RI; Slobodin, VB1
Carlson, J; Gholson, RK; Griffith, G; Suzuki, N1
Buchanan, JM1
Cederbaum, AI; Lieber, CS; Rubin, E1
LaNoue, KF; Safer, B; Smith, CM; Walajtys, E; Williamson, JR1
Mahadevan, S; Sauer, F1
Holmin, T; Siesjö, BK1
Dionisi, O; Eboli, ML; Galeotti, T; Longhi, G; Terranova, T1
Colman, RF; Siliski, JM1
Loy, E; Müllhofer, G1
Movsesian, SG1
Brand, MD; Chappell, JB1
Safer, H; Williamson, JR1
Aprison, MH; Graham, LT1
Felts, PW; Kreisberg, RA; Williamson, JR1
Anson, RW; Ballard, FJ1
Deodhar, AD; Mistry, SP1
Bryan, JK1
Yoshida, A1
Hariharan, K; Rao, DR; Vijayalakshmi, KR1
Ardouin, B; Baron, P; Doucet, C; Griffaton, G; Lowy, R1
Santarius, KA; Stocking, CR1
Cohen, GN; Le Bras, G; Stanier, RY1
Chamalaun, RA; Tager, JM1
Baron, P; Griffaton, G; Lowy, R2
Katsuki, H; Murai, T; Nagai, J; Tokushige, M2
Langer, BW; Smith, WJ; Theodorides, VJ1
Mihara, K; Sato, R; Shimakata, T1
Archer, K; Hartmann, HA; Schor, NA1
Moat, AG; Thomulka, KW1
Elmerich, C1
Harris, RL; Veech, EH; Veech, RL; Veloso, D1
Berdanier, CD; Shubeck, D1
Benavides, J; García, ML; Giménez-Gallego, G; Valdivieso, F1
Best, L; Malaisse, WJ; Malaisse-Lagae, F; Sener, A1
Arenas-Diaz, G; Martínez-Murillo, R; Martínez-Rodriguez, R1
Brdicka, R1
Hassinen, IE; Hiltunen, JK; Kauppinen, RA1
Heard, JT; Steiner, BM; Tritz, GJ1
Ledig, M; M'Paria, JR; Mandel, P1
Dawson, AG1
Cooney, DA; Han, N; Kensler, TW1
Koppenhafer, SL; Scholz, TD1
Cui, K; Lu, AY; Ma, Q; Yang, CS1
Catelloni, F; Fontaine, E; Keriel, C; Leverve, XM; Rigoulet, M; Sibille, B1
Inagaki, Y; Kimura, T; Sawai, T; Yamaguchi, A1
Bernard, N; Delcour, J; Holbrook, JJ; Johnsen, K1
Böhm, G; Jaenicke, R; Tomschy, A1
Alldread, RM; Atkinson, T; Clarke, AR; Halsall, DM; Nicholls, DJ; Scawen, MD; Sundaram, TK1
Scaduto, RC1
Li, Y; Man, WJ; O'Connor, CD; Wilton, DC1
Gerber, NC; Sligar, SG1
Deckers-Hebestreit, G; Hase, B; Strotmann, H; Werner-Grüne, S1
Hara, A; Kaibe, H; Matsuura, K; Mitsui, Y; Nakanishi, M; Nonaka, T; Tanaka, N1
Atlante, A; Gagliardi, S; Passarella, S1
Koppenhafer, SL; Scholz, TD; Schutte, BC; tenEyck, CJ1
Aoki, M; Ishimori, K; Morishima, I1
Chun, YS; Kim, MS; Kwak, SJ; Park, JW; Park, SC; Park, YC1
Barron, JT; Gu, L; Parrillo, JE1
Brady, RL; Chapman, AD; Clarke, AR; Cortés, A; Dafforn, TR1
Badii, R; Basran, J; Casarotto, MG; Roberts, GC; Sze, KH1
Rao, NA; Savithri, HS; Talwar, R1
Delley, M; Germond, JE; Hottinger, H; Kochhar, S; Lamzin, VS; Razeto, A1
Aarhus, R; Graeff, R; Lee, HC; Levitt, D; Munshi, C; Walseth, TF1
Jensen, RA; Luengo, JM; Miñambres, B; Olivera, ER1
Rupert, BE; Scholz, TD; Schutte, BC; Segar, JL1
Cleaves, HJ; Miller, SL1
Edwards, JS; McCulloch, A; Palsson, BO; Ramakrishna, R1
Gangloff, A; Garneau, A; Huang, YW; Lin, SX; Yang, F1
Bragg, PD; Hou, C1
Ballou, DP; Ludwig, ML; Matthews, RG; Trimmer, EE1
Arai, T; Kamata, S; Sako, T; Takahashi, M1
Moyer, RW; Shuman, S; Sriskanda, V1
Arai, T; Azakami, D; Ikeda, M; Takahashi, M; Washizu, T1
Shuman, S; Sriskanda, V1
Fujioka, M; Gomi, T; Huang, Y; Komoto, J; Ogawa, H; Takata, Y; Takusagawa, F; Yamada, T1
Miziorko, HM; Runquist, JA1
Arnold, P; Baker, ME; Frey, FJ; Odermatt, A; Tam, S; Yan, L1
Meijer, AJ1
Addlagatta, A; Brandt, S; Duax, WL; Fuller, RR; Norris, W; Thomas, JL1
KLITA, S; SZAFRANSKI, P1
TAGER, JM1
HERMIER, J; SIEGENTHALER, PA1
ALLAN, PW; TOMISEK, AJ1
COOPER, JR1
BURCHALL, JJ; NIEDERMAN, RA; WOLIN, MJ1
DURAND, R; GAUDEMER, Y; GAUTHERON, D; PIALOUX, N1
ARKY, RA; COHEN, AK; FOSTER, AE; FREINKEL, N1
CAMPBELL, JW; PRESCOTT, LM1
Begum, L; Horiuchi, M; Iijima, M; Jalil, MA; Kobayashi, K; Li, MX; Moriyama, M; Robinson, BH; Saheki, T; Sinasac, DS; Tsui, LC1
Hashimoto, T; Katoh, A1
Fushinobu, S; Shoun, H; Su, F; Takaya, N1
Shiro, Y; Shoun, H; Su, F; Takaya, N; Umemura, M1
Kobayashi, K; Saheki, T1
Amorini, AM; Cimatti, M; Delfini, R; Lazzarino, G; Marmarou, A; Signoretti, S; Tavazzi, B; Vagnozzi, R1
Cook, PF; Harris, BG; Karsten, WE; Liu, D; Rao, GS1
Ballou, DP; Brinker, DR; Casas, KR; Galloway, LJ; Scannell, SA; Trimmer, EE1
Banerjee, S; Ray, M; Ray, S; SinhaRoy, S1
Cabrera, ME; Saidel, GM; Stanley, WC; Yu, X; Zhou, L1
McKenna, MC; Schousboe, A; Sonnewald, U; Waagepetersen, HS1
Akita, M; Hashimoto, T; Katoh, A; Uenohara, K1
Atlante, A; De Bari, L; Marra, E; Passarella, S; Seccia, TM1
Bender, K; Brennan, L; Maechler, P; Newsholme, P1
Contreras, L; Gomez-Puertas, P; Iijima, M; Kobayashi, K; Saheki, T; Satrústegui, J1
Bzymek, KP; Colman, RF1
Katunuma, N; Ohshima, T; Sakuraba, H; Tsuge, H; Yoneda, K1
Arold, S; Assairi, L; Labesse, G; Pochet, S; Poncet-Montange, G1
Easlon, E; Lin, SJ; Skinner, C; Tsang, F; Wang, C1
Bairagya, HR; Mukhopadhyay, BP; Sekar, K1
Contreras, L; Satrústegui, J1
Lund, TM; Risa, O; Schousboe, A; Sonnewald, U; Waagepetersen, HS1
Kawakami, R; Ohshima, T; Oyama, M; Sakuraba, H1
Dutcher, SK; Kwan, AL; Lin, H1
Doi, K; Mutaguchi, Y; Ohmori, T; Ohshima, T; Sakuraba, H; Yoneda, K1
Ashida, H; Ishikawa, T; Kawakami, N; Li, Y; Ogola, HJ; Sawa, Y; Shibata, H1
Amorini, AM; Barrios, L; Di Pietro, V; Marmarou, A; Marmarou, CR; Pascual, JM; Prieto, R; Tavazzi, B; Taya, K1
Ashida, H; Ishida, M; Ishikawa, T; Li, Y; Sawa, Y; Shibata, H1
Li, Y; Ogola, HJ; Sawa, Y1
Abbrescia, DI; La Piana, G; Lofrumento, NE1
Hertz, L; Li, B; Peng, L1
Han, W; Min, W; Wang, D; Zhan, D1
Aksentijević, D; Brookes, PS; Chouchani, ET; Costa, ASH; Dare, AJ; Davidson, SM; Duchen, MR; Eaton, S; Eyassu, F; Frezza, C; Gaude, E; Hartley, RC; Hu, CH; James, AM; Krieg, T; Logan, A; Murphy, MP; Nadtochiy, SM; Ord, ENJ; Pell, VR; Robb, EL; Robinson, AJ; Rogatti, S; Saeb-Parsy, K; Shattock, MJ; Shirley, R; Smith, AC; Sundier, SY; Work, LM1
Banke, NH; Lewandowski, ED1
Guan, KL; Lin, H; Ling, ZQ; Shi, Q; Xiong, Y; Yang, H; Yang, Y; Ye, D; Zhang, M; Zhao, S; Zhao, Y; Zhou, L1
Bak, LK; Satrústegui, J1
Beal, MF; Clark-Matott, J; Dai, Y; Ma, X; Safdar, A; Saleem, A; Shurubor, Y; Simon, DK; Tarnopolsky, M1
Chen, J; Fernandez, J; Fernandez-Bueno, GA; Gusdon, AM; Mathews, CE; Wohlgemuth, S1
Couté, Y; Ollagnier de Choudens, S; Reichmann, D1
Amoedo, ND; De Grassi, A; Lacombe, D; Obre, E; Pierri, CL; Punzi, G; Rossignol, R1
Hong, KM; Jang, H; Kang, JH; Kim, SY; Lee, C; Lee, JS; Lee, SH; Nam, B; Seong, TW; Son, J1
Bush, LN; Davidson, SM; Freinkman, E; Gitego, N; Gui, DY; Hosios, AM; Luengo, A; Sullivan, LB; Thomas, CJ; Vander Heiden, MG1
Hong, D; Hong, KM; Kang, JH; Kim, SY; Lee, JS; Lee, SH; Son, J; Song, J1
Beyrath, J; Iannetti, EF; Koopman, WJH; Smeitink, JAM; Willems, PHGM1
Agius, L; Alshawi, A1
Altinok, O; Bowne, WB; Orynbayeva, Z; Poggio, JL; Shieh, AC; Snyder, NW; Stein, DE1
Appanna, VD; Appanna, VP; Bley, AM; MacLean, A1
Chen, C; Chen, GQ; Chen, X; Gu, H; Hao, X; He, X; Huang, D; Lai, X; Lin, SH; Liu, L; Loscalzo, J; Su, N; Xie, L; Yang, Y; Yu, Z; Zhang, X; Zhang, Y; Zhao, Y; Zheng, D; Zheng, J; Zou, Y1
Gao, J; Zhang, YW; Zhou, Q1
But, SY; Khmelenina, VN; Mustakhimov, II; Reshetnikov, AS; Rozova, ON1
Guo, M; Jiang, X; Tang, W; Xu, H1
Bharti, S; Bhujwalla, Z; Gabrielson, E; Tully, E; Woo, J1
Kawai-Yamada, M; Konishi, M; Miyagi, A; Saito, M; Sakuraba, Y; Yanagisawa, S1
Fowle-Grider, R; Patti, GJ; Schwaiger-Haber, M; Shriver, LP; Stancliffe, E; Wang, C; Wang, R; Wang, Y1
Luo, J; Mu, X; Wang, Z; Yang, Q; Zhao, Y1
Bernitzky, CCM; Greetham, GM; Higuchi, Y; Horch, M; Hunt, NT; Ishii, M; Karafoulidi-Retsou, C; Kulka-Peschke, CJ; Lauterbach, L; Lenz, O; Lorent, C; Matsuura, H; Preissler, J; Procacci, B; Rippers, Y; Schulz, AC; Schulz, C; Teutloff, C; Wahlefeld, S; Wiemann, C; Wrathall, SLD; Zebger, I1
Chen, GB; Francisco, JC; Li, S; Singh, BK; Thimmukonda, NK; Yau, WW; Yen, PM; Zhou, J1
Carlisle, SM; Davidsen, K; Engstrom, IA; Hart, ML; Hoellerbauer, P; Newsom, OJ; Quon, E; Sullivan, LB; Vigil, ABG1
Ben-Sahra, I; Bost, F; Contenti, J; Guo, Y; Irondelle, M; Lago, C; Leva, G; Mazure, NM; Mazzu, A; Rouleau, M; Tiberi, L1

Reviews

17 review(s) available for nad and aspartic acid

ArticleYear
The Metabolic Significance of the Malate-Aspartate Cycle in Heart.
    Circulation research, 1975, Volume: 37, Issue:5

    Topics: Animals; Anions; Aspartic Acid; Citric Acid Cycle; Cytosol; Glycolysis; Humans; Malates; Myocardium; NAD; Oxidation-Reduction

1975
[Role of adenine mono- and dinucleotides in ammonia formation in brain tissue].
    Voprosy biokhimii mozga, 1975, Volume: 10

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Ammonia; AMP Deaminase; Animals; Aspartic Acid; Brain; Cyclic AMP; Deamination; Enzyme Activation; Glycolysis; Hexokinase; Inosine Nucleotides; Insulin; Isoenzymes; Liver; Mitochondria; Muscles; NAD; Rats

1975
Metabolic adaptations of intertidal invertebrates to environmental hypoxia (a comparison of environmental anoxia to exercise anoxia).
    Symposia of the Society for Experimental Biology, 1985, Volume: 39

    Topics: Adaptation, Physiological; Adenosine Triphosphate; Alanine; Anaerobiosis; Animals; Annelida; Aspartic Acid; Crustacea; Glycogen; Mollusca; NAD; Nematoda; Oxygen; Pyruvate Oxidase; Pyruvates; Seawater

1985
Structure, function, and possible origin of a bifunctional allosteric enzyme, Escherichia coli aspartokinase I-homoserine dehydrogenase I.
    CRC critical reviews in biochemistry, 1974, Volume: 2, Issue:3

    Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Allosteric Regulation; Amino Acids; Antigen-Antibody Reactions; Aspartic Acid; Binding Sites; Electrophoresis, Disc; Escherichia coli; Homoserine; Kinetics; Mercaptopurine; Molecular Weight; Multienzyme Complexes; NAD; NADP; Peptide Fragments; Phosphotransferases; Protein Binding; Protein Conformation; Ribonucleotides; Serine; Spectrophotometry; Sulfhydryl Compounds; Threonine

1974
[Mechanisms of ammonia formation in the brain].
    Voprosy biokhimii mozga, 1973, Volume: 8

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Oxidoreductases; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Brain Chemistry; Deamination; Dogs; Flavin-Adenine Dinucleotide; Fumarates; Glutamate Dehydrogenase; Glutaminase; Glutamine; Guanosine Triphosphate; Inosine Nucleotides; Mitochondria; Monoamine Oxidase; NAD; NADP; Nerve Tissue Proteins; Niacinamide; Oxidation-Reduction; Oxygen Consumption; Rats

1973
Transients and relaxation kinetics of enzyme reactions.
    Annual review of biochemistry, 1971, Volume: 40

    Topics: Alcohol Oxidoreductases; Animals; Aspartic Acid; Catalase; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Computers; Endopeptidases; Enzymes; Escherichia coli; Flavoproteins; Glutamate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemoglobins; Homoserine; Horses; Hot Temperature; Kinetics; L-Lactate Dehydrogenase; Liver; Macromolecular Substances; Mathematics; Models, Biological; Muramidase; Myoglobin; NAD; Pancreas; Papain; Peroxidases; Phosphoric Monoester Hydrolases; Phosphotransferases; Protein Binding; Protein Conformation; Ribonucleases; Spectrophotometry; Temperature

1971
Phosphoenolpyruvate carboxykinase. I. Its role in gluconeogenesis.
    The American journal of clinical nutrition, 1972, Volume: 25, Issue:10

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Carboxy-Lyases; Cytosol; Fasting; Feeding Behavior; Gluconeogenesis; Guanosine Triphosphate; Guinea Pigs; Humans; Ligases; Liver; Malates; Mitochondria, Liver; NAD; Oxaloacetates; Phosphoenolpyruvate; Pyruvates; Rabbits; Rats; Species Specificity

1972
The amidotransferases.
    Advances in enzymology and related areas of molecular biology, 1973, Volume: 39

    Topics: Anthranilate Synthase; Asparagine; Aspartic Acid; Binding Sites; Carbamates; Cytosine Nucleotides; Fructosephosphates; Glutamine; Ligases; Liver; Macromolecular Substances; NAD; Organophosphorus Compounds; Protein Conformation; Pyrimidine Nucleotides; Ribose; RNA, Transfer; Transaminases; Xanthines

1973
Mitochondrial-cytosolic interactions in cardiac tissue: role of the malate-aspartate cycle in the removal of glycolytic NADH from the cytosol.
    Symposia of the Society for Experimental Biology, 1973, Volume: 27

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Carbon Radioisotopes; Cytosol; Flavoproteins; Fluorometry; Glucose; Glutamates; Glycolysis; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Ketone Oxidoreductases; Lactates; Malates; Mitochondria, Muscle; Myocardium; NAD; Oligomycins; Oxidation-Reduction; Oxygen Consumption; Perfusion; Phosphates; Rats; Tritium

1973
Amino acids as regulators and components of nonproteinogenic pathways.
    The Journal of nutrition, 2003, Volume: 133, Issue:6 Suppl 1

    Topics: Amino Acids; Animals; Aspartic Acid; Cell Size; Glutamic Acid; Humans; Insulin; Islets of Langerhans; Metabolism; NAD; Oxidation-Reduction; Signal Transduction; Urea

2003
Molecular biology of pyridine nucleotide and nicotine biosynthesis.
    Frontiers in bioscience : a journal and virtual library, 2004, May-01, Volume: 9

    Topics: Animals; Aspartic Acid; Bacteria; Gene Expression; Kynurenine; Mammals; Models, Chemical; NAD; Nicotiana; Nicotine; Plants; Yeasts

2004
[Molecular basis of citrin deficiency].
    Seikagaku. The Journal of Japanese Biochemical Society, 2004, Volume: 76, Issue:12

    Topics: Aspartic Acid; Calcium; Calcium-Binding Proteins; Cholestasis, Intrahepatic; Chromosome Mapping; Citrullinemia; Gene Frequency; Homozygote; Humans; Infant, Newborn; Maleates; Membrane Transport Proteins; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Mutation; NAD; Organic Anion Transporters

2004
Neuronal and astrocytic shuttle mechanisms for cytosolic-mitochondrial transfer of reducing equivalents: current evidence and pharmacological tools.
    Biochemical pharmacology, 2006, Feb-14, Volume: 71, Issue:4

    Topics: Animals; Aspartic Acid; Astrocytes; Biological Transport; Cytosol; Glycerophosphates; Malates; Mitochondria; Models, Biological; NAD; Neurons; Oxidation-Reduction

2006
L-aspartate dehydrogenase: features and applications.
    Applied microbiology and biotechnology, 2012, Volume: 93, Issue:2

    Topics: Amino Acid Oxidoreductases; Aspartic Acid; Biotechnology; NAD; Oxidation-Reduction

2012
Fluctuations in Cytosolic Calcium Regulate the Neuronal Malate-Aspartate NADH Shuttle: Implications for Neuronal Energy Metabolism.
    Neurochemical research, 2015, Volume: 40, Issue:12

    Topics: Animals; Aspartic Acid; Calcium Signaling; Cytosol; Energy Metabolism; Humans; Lactic Acid; Malates; Mitochondria; NAD; Neurons

2015
AGC1/2, the mitochondrial aspartate-glutamate carriers.
    Biochimica et biophysica acta, 2016, Volume: 1863, Issue:10

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Biological Transport, Active; Calcium-Binding Proteins; Cattle; Consensus Sequence; Glutamic Acid; Humans; Malates; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Models, Molecular; NAD; Neoplasm Proteins; Organ Specificity; Organic Anion Transporters; Oxidation-Reduction; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid

2016
Metabolic manipulation by
    Journal of medical microbiology, 2020, Volume: 69, Issue:3

    Topics: Adenosine Triphosphate; Aspartic Acid; Homeostasis; Metabolic Networks and Pathways; Metals; NAD; NADP; Oxalates; Oxidation-Reduction; Oxidative Stress; Pseudomonas fluorescens; Reactive Oxygen Species; Stress, Physiological

2020

Other Studies

233 other study(ies) available for nad and aspartic acid

ArticleYear
Evidence for a critical glutamyl and an aspartyl residue in the function of pig heart diphosphopyridine nucleotide dependent isocitrate dehydrogenase.
    Biochemistry, 1977, Apr-19, Volume: 16, Issue:8

    Topics: Animals; Aspartic Acid; Binding Sites; Glutamates; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Myocardium; NAD; Protein Binding; Swine; Temperature

1977
Some effects of glucose concentration and anoxia on glycolysis and metabolite concentrations in the perfused liver of fetal guinea pig.
    Biochimica et biophysica acta, 1978, Jan-03, Volume: 538, Issue:1

    Topics: Adenine Nucleotides; Animals; Aspartic Acid; Citric Acid Cycle; Female; Fructosediphosphates; Gestational Age; Glucose; Glutamates; Glycogen; Glycolysis; Guinea Pigs; Hypoxia; Liver; Male; NAD; NADP; Pentosephosphates; Perfusion; Pregnancy

1978
Methodology for transport studies: graphical and computer curve fitting methods for glutamate and aspartate efflux kinetics.
    Methods in enzymology, 1979, Volume: 56

    Topics: Animals; Aspartic Acid; Biological Transport; Computers; Glutamates; Kinetics; Mathematics; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Rats

1979
Isolation of a metabolite capable of differentially supporting the growth of nicotinamide adenine dinucleotide auxotrophs of Escherichia coli.
    Journal of bacteriology, 1975, Volume: 121, Issue:1

    Topics: Aspartic Acid; Escherichia coli; Mutation; NAD; Niacinamide; Nicotinic Acids; Quinolinic Acids

1975
Studies on the active transfer of reducing equivalents into mitochondria via the malate-aspartate shuttle.
    Biochimica et biophysica acta, 1975, Mar-20, Volume: 376, Issue:3

    Topics: Adenosine Triphosphate; Animals; Arsenic; Aspartic Acid; Biological Transport, Active; Carnitine; Dinitrophenols; Electron Transport; Glutamates; Hydroxybutyrates; Malates; Mitochondria, Liver; NAD; Oligomycins; Oxidation-Reduction; Palmitic Acids; Rats; Rotenone

1975
Vitamin E deficiency in the rat. Cytoplasmic factors required for suppression of mitochondrial respiratory decline.
    The Journal of nutrition, 1975, Volume: 105, Issue:5

    Topics: Animals; Aspartic Acid; Cell Fractionation; Cytoplasm; Dialysis; Hydroxybutyrates; Ketoglutaric Acids; Liver; Microsomes, Liver; Mitochondria, Liver; NAD; Oxaloacetates; Oxidation-Reduction; Oxygen Consumption; Rats; Subcellular Fractions; Vitamin E Deficiency

1975
Molecular injury to mitochondria produced by ethanol and acetaldehyde.
    Federation proceedings, 1975, Volume: 34, Issue:11

    Topics: Acetaldehyde; Adenosine Triphosphatases; Alcohol Oxidoreductases; Alcoholism; Animals; Aspartic Acid; Biological Transport; Calcium; Cytosol; Ethanol; Fatty Acids; Glycerolphosphate Dehydrogenase; Glycerophosphates; Humans; Liver; Malates; Male; Mitochondria, Liver; NAD; Oxidative Phosphorylation; Oxygen Consumption; Rats

1975
Neurospora crassa conidial germination: role of endogenous amino acid pools.
    Journal of bacteriology, 1975, Volume: 124, Issue:1

    Topics: Amino Acids; Aminobutyrates; Aspartic Acid; Chromatography; Cycloheximide; Flavin-Adenine Dinucleotide; Glutamates; NAD; Neurospora; Neurospora crassa; Spores, Fungal; Water

1975
Occurrence of the malate-aspartate shuttle in various tumor types.
    Cancer research, 1976, Volume: 36, Issue:4

    Topics: Aminooxyacetic Acid; Animals; Antimycin A; Aspartic Acid; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Krebs 2; Cell Line; Cyanides; Kinetics; Lactates; Leukemia L1210; Liver Neoplasms; Malates; Malonates; Mitochondria; NAD; Neoplasms, Experimental; Oxidation-Reduction; Pyruvates; Rotenone; Tricarboxylic Acids

1976
Studies on the control of 4-aminobutyrate metabolism in 'synaptosomal' and free rat brain mitochondria.
    The Biochemical journal, 1976, Nov-15, Volume: 160, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Aminobutyrates; Animals; Aspartic Acid; Biological Transport; Brain; gamma-Aminobutyric Acid; Glutamates; Ketoglutaric Acids; Male; Mitochondria; NAD; Potassium; Rats; Rotenone; Synaptosomes

1976
Detection of precursors of quinolinic acid in Escherichia coli.
    Microbios, 1976, Volume: 16, Issue:65-66

    Topics: Adenosine Triphosphate; Aspartic Acid; Cell-Free System; Chemical Phenomena; Chemistry; Dihydroxyacetone Phosphate; Escherichia coli; Flavin-Adenine Dinucleotide; Fructosephosphates; Ligases; NAD; Nicotinic Acids; Pyridines; Quinolinic Acids

1976
Magnitude of malate-aspartate reduced nicotinamide adenine dinucleotide shuttle activity in intact respiring tumor cells.
    Cancer research, 1977, Volume: 37, Issue:11

    Topics: Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Citric Acid Cycle; Cytosol; Electron Transport; Glucose; Glycolysis; In Vitro Techniques; Lactates; Malates; Mice; Mitochondria; NAD; Neoplasms, Experimental; Oxygen Consumption; Pyruvates

1977
[Effect of NAD recirculation on the mechanism of ATP stabilization in cytoplasm. Mathematical models].
    Biokhimiia (Moscow, Russia), 1977, Volume: 42, Issue:9

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aspartic Acid; Cytoplasm; Glycerophosphates; Glycolysis; Malates; Mathematics; Mitochondria; Models, Biological; NAD; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Phosphotransferases

1977
The operation of the malate-aspartate shuttle in the reoxidation of glycolytic NADH in slices of fetal rat liver.
    Biochimica et biophysica acta, 1977, Dec-23, Volume: 462, Issue:3

    Topics: Adenosine Triphosphate; Aerobiosis; Aminooxyacetic Acid; Animals; Aspartic Acid; Cytosol; Fetus; Glycolysis; In Vitro Techniques; Lactates; Liver; Malates; NAD; Oxidation-Reduction; Rats

1977
Evidence for the oxidation of glycolytic NADH by the malate-aspartate shuttle in Ehrlich ascites tumor cells.
    Archives of biochemistry and biophysics, 1979, Volume: 192, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Dihydroxyacetone Phosphate; Fructosediphosphates; Glucose; Glycolysis; Kinetics; Malates; Mice; NAD; Oxidation-Reduction

1979
Incorporation of the hydrogen atoms of ethanol into amino acids in rat liver in vivo.
    Biochimica et biophysica acta, 1979, Mar-07, Volume: 583, Issue:2

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Deuterium; Ethanol; Female; Glutamates; Hydrogen; Liver; NAD; Proline; Rats

1979
Quantitative evaluation of the activity of the malate-aspartate shuttle in Ehrlich ascites tumor cells.
    Cancer research, 1979, Volume: 39, Issue:6 Pt 1

    Topics: Aminooxyacetic Acid; Animals; Arsenic; Aspartic Acid; Carcinoma, Ehrlich Tumor; Glucose; Glycolysis; L-Lactate Dehydrogenase; Malates; Mice; NAD; Oxamic Acid; Oxidation-Reduction; Oxygen Consumption

1979
Reconstitution of malate-aspartate and alpha-glycerophosphate shuttle activity in rat skeletal muscle mitochondria.
    The International journal of biochemistry, 1979, Volume: 10, Issue:5

    Topics: Animals; Aspartic Acid; Electron Transport; Glycerophosphates; Malates; Male; Mitochondria, Muscle; NAD; Rats; Rotenone; Uncoupling Agents

1979
Mitochondrial shuttle activities in hyperthyroid and normal rats and guinea pigs.
    Journal of environmental pathology and toxicology, 1979, Volume: 3, Issue:1-2

    Topics: Adenosine Diphosphate; Animals; Aspartic Acid; Cyanides; Glycerophosphates; Guinea Pigs; Hyperthyroidism; Ketone Bodies; Kidney; Lactates; Malates; Mitochondria; Mitochondria, Liver; NAD; Oxygen Consumption; Pyruvates; Rats; Rotenone

1979
CO2 fixation and its regulation in Anacystis nidulans (Synechococcus).
    Archives of microbiology, 1975, Volume: 102, Issue:1

    Topics: Adenosine Monophosphate; Amino Acids; Aspartic Acid; Carbon Dioxide; Carbon Radioisotopes; Carbonic Acid; Culture Media; Cyanobacteria; Glyceraldehyde-3-Phosphate Dehydrogenases; Light; NAD; NADP; Pentosephosphates; Phosphates; Phosphorus Radioisotopes; Species Specificity; Sugar Phosphates

1975
On mechanisms in hyperammonemic coma--with particular reference to hepatic encephalopathy.
    Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ammonia; Aspartic Acid; Brain; Dose-Response Relationship, Drug; Energy Metabolism; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hepatic Encephalopathy; Humans; Ketoglutaric Acids; Mitochondria, Liver; NAD; Oxidation-Reduction; Time Factors

1975
Studies on the de novo biosynthesis of NAD in Escherichia coli. The separation of the nadB gene product from the nadA gene product and its purification.
    European journal of biochemistry, 1975, Volume: 54, Issue:1

    Topics: Aspartic Acid; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Escherichia coli; Genetic Complementation Test; Genetics, Microbial; Hydroxyapatites; Macromolecular Substances; Multienzyme Complexes; Mutation; NAD; NADP; Organophosphorus Compounds; Protein Biosynthesis; Trioses

1975
Oxidation of cytosolic NADH by the malate-aspartate shuttle in HuH13 human hepatoma cells.
    The International journal of biochemistry, 1992, Volume: 24, Issue:2

    Topics: Aspartic Acid; Carcinoma, Hepatocellular; Cytosol; Humans; Kinetics; Liver Neoplasms; Malates; NAD; Oxidation-Reduction; Tumor Cells, Cultured

1992
Reducing-equivalent transfer to the mitochondria during gluconeogenesis and ureogenesis in hepatocytes from rats of different thyroid status.
    Biochimica et biophysica acta, 1992, Oct-06, Volume: 1137, Issue:1

    Topics: Alanine; Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Cytoplasm; Gluconeogenesis; Glutamates; Glutamic Acid; Hydrogen; Hyperthyroidism; Hypothyroidism; Male; Malonates; Mitochondria, Liver; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Thyroid Gland; Urea

1992
Interactions between mitochondria and cytoplasm in isolated hepatocytes.
    Current topics in cellular regulation, 1992, Volume: 33

    Topics: Animals; Aspartic Acid; Biological Transport; Cytoplasm; Energy Metabolism; Enzymes; Glucose; Glycolysis; Liver; Malates; Male; Mitochondria, Liver; Multienzyme Complexes; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains

1992
Operation and energy dependence of the reducing-equivalent shuttles during lactate metabolism by isolated hepatocytes.
    Biochimica et biophysica acta, 1992, Sep-09, Volume: 1136, Issue:3

    Topics: Ammonia; Animals; Aspartic Acid; Cytoplasm; Energy Metabolism; Gluconeogenesis; Lactates; Lactic Acid; Liver; Malates; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Palmitates; Rats; Rats, Inbred Strains; Valinomycin

1992
Inhibition of malate-aspartate shuttle by the antitumor drug L-glutamic acid gamma-monohydroxamate in L1210 leukemia cells.
    International journal of cancer, 1992, May-08, Volume: 51, Issue:2

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Glutamates; Hydroxamic Acids; Hydroxylamine; Hydroxylamines; Leukemia L1210; Malates; NAD

1992
Characterization and nucleotide binding properties of a mutant dihydropteridine reductase containing an aspartate 37-isoleucine replacement.
    The Journal of biological chemistry, 1992, Aug-05, Volume: 267, Issue:22

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Dihydropteridine Reductase; Escherichia coli; Isoleucine; Kinetics; Liver; Mutagenesis, Site-Directed; NAD; NADP; Protein Conformation; Rats; Recombinant Proteins

1992
Role of aspartic acid 38 in the cofactor specificity of Drosophila alcohol dehydrogenase.
    European journal of biochemistry, 1991, Dec-05, Volume: 202, Issue:2

    Topics: Alcohol Dehydrogenase; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Blotting, Western; Drosophila; Electrophoresis, Polyacrylamide Gel; Horses; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Models, Molecular; Molecular Sequence Data; Mutation; NAD; NADP; Protein Denaturation; Sequence Homology, Nucleic Acid

1991
Role of aspartate-37 in determining cofactor specificity and binding in rat liver dihydropteridine reductase.
    Archives of biochemistry and biophysics, 1991, Volume: 287, Issue:2

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; Blotting, Western; Dihydropteridine Reductase; Escherichia coli; Gene Expression; Kinetics; Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Fragments; Plasmids; Rats; Recombinant Proteins; Transformation, Genetic

1991
Flow-injection analysis of amino acids and their metabolites by immobilized vitamin B6-dependent enzymes. Sensitive determination of L-aspartate, L-glutamate, 2-oxoglutarate, and oxaloacetate.
    Annals of the New York Academy of Sciences, 1990, Volume: 585

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Cattle; Enzymes, Immobilized; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Luminescent Measurements; Malate Dehydrogenase; NAD; Oxaloacetates; Pyridoxine

1990
Site-directed mutagenesis of rat liver S-adenosylhomocysteinase. Effect of conversion of aspartic acid 244 to glutamic acid on coenzyme binding.
    The Journal of biological chemistry, 1990, Sep-25, Volume: 265, Issue:27

    Topics: Adenosylhomocysteinase; Apoenzymes; Aspartic Acid; Base Sequence; Binding Sites; Cloning, Molecular; Escherichia coli; Glutamates; Glutamic Acid; Hydrolases; Kinetics; Liver; Molecular Sequence Data; Molecular Weight; Mutation; NAD; Oligonucleotide Probes; Recombinant Proteins

1990
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
    Biochemistry, 1990, Sep-18, Volume: 29, Issue:37

    Topics: Adenosine Diphosphate Ribose; Affinity Labels; Aspartic Acid; Base Sequence; Binding Sites; Diphtheria Toxin; Glutamates; Glutamic Acid; Glutamine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Serine; Substrate Specificity

1990
An aspartate residue in yeast alcohol dehydrogenase I determines the specificity for coenzyme.
    Biochemistry, 1991, Jul-02, Volume: 30, Issue:26

    Topics: Alcohol Dehydrogenase; Amino Acid Sequence; Aspartic Acid; Base Sequence; Flavin-Adenine Dinucleotide; Kinetics; Models, Molecular; Molecular Sequence Data; NAD; Oligonucleotide Probes; Protein Conformation; Saccharomyces cerevisiae; Substrate Specificity

1991
Identification of the principal catalytically important acidic residue of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
    The Journal of biological chemistry, 1990, Dec-15, Volume: 265, Issue:35

    Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Chromatography, Affinity; Cloning, Molecular; Coenzyme A; DNA Mutational Analysis; Glutamates; Glutaral; Hydroxymethylglutaryl CoA Reductases; Kinetics; Mevalonic Acid; Molecular Sequence Data; NAD; Oligonucleotides; Pseudomonas; Structure-Activity Relationship

1990
Acute and chronic ethanol treatment in vivo increases malate-aspartate shuttle capacity in perfused rat liver.
    The Journal of biological chemistry, 1990, Dec-15, Volume: 265, Issue:35

    Topics: Alanine; Aminooxyacetic Acid; Animals; Aspartic Acid; Biological Transport; Cytoplasm; Ethanol; Female; Glucose; Lactates; Liver; Malates; Mitochondria, Liver; NAD; Oxygen Consumption; Rats; Rats, Inbred Strains; Sorbitol; Time Factors

1990
Cytosolic free calcium and NAD/NADH redox state in the cat cortex during in vivo activation of NMDA receptors.
    Brain research, 1989, Mar-13, Volume: 482, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cats; Cerebral Cortex; Cytosol; Fluorescent Dyes; In Vitro Techniques; Male; N-Methylaspartate; NAD; Oxidation-Reduction; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine

1989
Aspartyl peptide labeled by 2-(4-bromo-2,3-dioxobutylthio)adenosine 5'-diphosphate in the allosteric ADP site of pig heart NAD+-dependent isocitrate dehydrogenase.
    The Journal of biological chemistry, 1989, Jul-25, Volume: 264, Issue:21

    Topics: Adenosine Diphosphate; Affinity Labels; Allosteric Site; Amino Acid Sequence; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Iodoacetates; Iodoacetic Acid; Isocitrate Dehydrogenase; Macromolecular Substances; Molecular Sequence Data; Myocardium; NAD; Peptide Fragments; Swine; Thionucleotides; Trypsin

1989
Oxidation of cytosolic NADH by the malate-aspartate shuttle in MC29 hepatoma cells.
    Cell biology international reports, 1989, Volume: 13, Issue:9

    Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Chickens; Cytosol; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid

1989
Diphtheria toxin. Effect of substituting aspartic acid for glutamic acid 148 on ADP-ribosyltransferase activity.
    The Journal of biological chemistry, 1985, Sep-05, Volume: 260, Issue:19

    Topics: Aspartic Acid; Base Sequence; Binding Sites; Cloning, Molecular; Corynebacterium diphtheriae; Diphtheria Toxin; Escherichia coli; Genes; Genes, Bacterial; Glutamates; Glutamic Acid; Mutation; NAD; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Protein Binding

1985
In vivo and in vitro adenosine stimulation of ethanol oxidation by hepatocytes, and the role of the malate-aspartate shuttle.
    Biochimica et biophysica acta, 1987, Sep-14, Volume: 930, Issue:2

    Topics: Adenosine; Animals; Aspartic Acid; Ethanol; Glutamates; Glutamic Acid; In Vitro Techniques; Liver; Malates; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains

1987
Diet effects on membrane phospholipid fatty acids and mitochondrial function in BHE rats.
    The Journal of nutrition, 1986, Volume: 116, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Aspartic Acid; Coconut Oil; Corn Oil; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Fatty Acids; Glycerophosphates; Malates; Male; Membrane Lipids; Mitochondria, Liver; NAD; Oils; Phospholipids; Plant Oils; Rats; Rats, Mutant Strains

1986
Significance of Cys-153 for the phosphatase activity of glyceraldehyde-3-phosphate dehydrogenase.
    Biomedica biochimica acta, 1985, Volume: 44, Issue:9

    Topics: Acid Anhydride Hydrolases; Acylphosphatase; Animals; Aspartic Acid; Cystine; Edetic Acid; Enzyme Activation; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycine; Ligands; NAD; Phenanthrolines; Phosphoric Monoester Hydrolases; Swine

1985
Site-directed mutagenesis of citrate synthase; the role of the active-site aspartate in the binding of acetyl-CoA but not oxaloacetate.
    Biochimica et biophysica acta, 1988, Apr-14, Volume: 953, Issue:3

    Topics: Acetyl Coenzyme A; Aspartic Acid; Bacteriophages; Base Sequence; Binding Sites; Citrate (si)-Synthase; Cloning, Molecular; DNA, Recombinant; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Immunoassay; Mutation; NAD; Oxaloacetates; Oxo-Acid-Lyases; Plasmids; Structure-Activity Relationship; Transformation, Bacterial

1988
Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates.
    Biochimica et biophysica acta, 1987, Sep-14, Volume: 930, Issue:2

    Topics: Acetates; Aminooxyacetic Acid; Animals; Aspartic Acid; Glycolysis; Guinea Pigs; In Vitro Techniques; Malates; Membrane Potentials; Mitochondria; NAD; Onium Compounds; Organophosphorus Compounds; Oxygen Consumption; Synaptosomes

1987
Importance of the malate-aspartate shuttle for the reoxidation of glycolytically produced NADH and for cell aggregation in porcine blood platelets.
    Acta biochimica Polonica, 1987, Volume: 34, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Blood Platelets; Cytosol; Glycolysis; Malate Dehydrogenase; Malates; Mitochondria; NAD; Oxidation-Reduction; Oxygen Consumption; Platelet Aggregation; Swine; Uncoupling Agents

1987
Oxidation of reduced cytosolic nicotinamide adenine dinucleotide by the malate-aspartate shuttle in the K-562 human leukemia cell line.
    Cancer research, 1986, Volume: 46, Issue:11

    Topics: Aminooxyacetic Acid; Arsenic; Arsenites; Aspartate Aminotransferases; Aspartic Acid; Cells, Cultured; Electron Transport; Humans; Lactates; Leukemia, Experimental; Malates; Mitochondria; NAD; Oxidation-Reduction; Pyruvates

1986
Glutamate dehydrogenase from Mycoplasma laidlawii.
    Journal of bacteriology, 1972, Volume: 110, Issue:2

    Topics: Acholeplasma laidlawii; Ammonium Sulfate; Aspartic Acid; Cell-Free System; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Coenzymes; Electrophoresis, Disc; Glutamate Dehydrogenase; Hot Temperature; Hydrogen-Ion Concentration; Ketoglutaric Acids; Molecular Weight; Mycoplasma; NAD; NADP; Purine Nucleotides; Pyruvates; Staining and Labeling

1972
Regulation of the nicotinamide adenine dinucleotide- and nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenases of Saccharomyces cerevisiae.
    Journal of bacteriology, 1973, Volume: 116, Issue:1

    Topics: Amino Acids; Ammonia; Asparaginase; Aspartic Acid; Carbon; Cell-Free System; Culture Media; Glutamate Dehydrogenase; Glutamates; Methylamines; NAD; NADP; Nitrogen; Saccharomyces cerevisiae; Spectrophotometry

1973
NAD malic enzyme in leaves with C-pathway photosynthesis and its role in C4 acid decarboxylation.
    Archives of biochemistry and biophysics, 1974, Volume: 160, Issue:1

    Topics: Acetyl Coenzyme A; Aspartate Aminotransferases; Aspartic Acid; Catalase; Centrifugation, Density Gradient; Chlorophyll; Fumarate Hydratase; Magnesium; Malate Dehydrogenase; Malates; Manganese; NAD; NADP; Photosynthesis; Plants; Species Specificity; Spectrophotometry, Ultraviolet; Sulfates

1974
Mechanisms for the formation of alanine and aspartate on rat liver in vivo after administration of ammonium chloride.
    The Biochemical journal, 1974, Volume: 138, Issue:3

    Topics: Alanine; Alanine Transaminase; Ammonia; Ammonium Chloride; Animals; Arginine; Aspartic Acid; Centrifugation; Cycloserine; Ketoglutaric Acids; Liver; Male; NAD; NADP; Rats; Time Factors; Urea

1974
Rabbit muscle lactate dehydrogenase 5; a regulatory enzyme.
    Science (New York, N.Y.), 1965, Oct-15, Volume: 150, Issue:3694

    Topics: Aconitum; Animals; Aspartic Acid; Citrates; Glutamates; In Vitro Techniques; Ketoglutaric Acids; Kinetics; L-Lactate Dehydrogenase; Lactates; Malates; Muscles; Myocardium; NAD; Oxaloacetates; Pyruvates; Rabbits; Succinates

1965
Nicotinic acid biosynthesis in prototrophs and tryptophan auxotrophs of Saccharomyces cerevisiae.
    The Journal of biological chemistry, 1966, Feb-25, Volume: 241, Issue:4

    Topics: Amidohydrolases; Aspartic Acid; Glutamates; In Vitro Techniques; Molecular Biology; Mutation; NAD; Nicotinic Acids; Oxidoreductases; Pyridines; Saccharomyces; Tryptophan

1966
Biosynthesis of NAD and nicotinic acid by Clostridium butylicum.
    Biochemical and biophysical research communications, 1966, Mar-08, Volume: 22, Issue:5

    Topics: Alanine; Aspartic Acid; Clostridium; Coenzyme A; Glycerol; In Vitro Techniques; NAD; Nicotinic Acids; Phosphates; Pyridines; Pyruvates; Succinates

1966
Colorimetric assays for serum alanine transaminase and lactic dehydrogenase using diazonium zinc salt.
    Analytical biochemistry, 1966, Volume: 17, Issue:1

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Aspartic Acid; Colorimetry; Glutamates; Glutarates; Indicators and Reagents; L-Lactate Dehydrogenase; Malate Dehydrogenase; Malates; NAD; Oxaloacetates; Pyridoxal Phosphate; Pyruvates

1966
Generation of extramitochondrial reducing power in gluconeogenesis.
    The Biochemical journal, 1967, Volume: 102, Issue:1

    Topics: Alcohol Oxidoreductases; Animals; Aspartic Acid; Cytoplasm; Ethanol; Gluconeogenesis; In Vitro Techniques; Kidney; Lactates; Liver; Mice; NAD; Oxaloacetates; Pyruvates; Rats; Serine

1967
Carbon dioxide fixation and phosphoenolpyruvate carboxylase in Ferrobacillus ferrooxidans.
    Canadian journal of microbiology, 1967, Volume: 13, Issue:11

    Topics: Adenosine Triphosphate; Aspartic Acid; Bacteria; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cell-Free System; Citrates; Coenzyme A; Glutamates; Hydrogen-Ion Concentration; Ketoglutaric Acids; Lyases; Magnesium; Malate Dehydrogenase; Malates; Manganese; NAD; Phosphates; Pyruvates; Spectrophotometry; Succinates; Threonine

1967
Evidence of reduction of fumarate to succinate in perfused rat liver under conditions of reduced O2 tension.
    Biochimica et biophysica acta, 1967, Nov-28, Volume: 148, Issue:2

    Topics: Animals; Aspartic Acid; Citrates; Electron Transport; Fumarates; Glutamates; Glycerophosphates; In Vitro Techniques; Lactates; Liver; Malates; Male; Malonates; NAD; Oxygen; Pressure; Rats; Rotenone; Succinates; Tritium

1967
Allosteric activation of DPN-linked malic enzyme from Escherichia coli by aspartate.
    Biochemical and biophysical research communications, 1967, Dec-15, Volume: 29, Issue:5

    Topics: Aspartic Acid; Cellulose; Chemical Phenomena; Chemistry, Physical; Chromatography, Ion Exchange; Escherichia coli; Hot Temperature; Kinetics; Malate Dehydrogenase; Malates; Models, Biological; NAD; Spectrophotometry; Stimulation, Chemical

1967
Further studies on the oxidation of extramitochondrial reduced nicotineamide-adenine dinucleotide in Landschuetz ascites tumor cells.
    European journal of biochemistry, 1968, Volume: 5, Issue:1

    Topics: Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Culture Techniques; Cytoplasm; Ketoglutaric Acids; Lactates; Manometry; NAD; Neoplasms, Experimental; Oxaloacetates; Oxidation-Reduction

1968
[Research on the mechanism of oxidations in Pseudomonas fluorescens. IV. Role of dihydroorotate dehydrogenase].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1967, Volume: 161, Issue:12

    Topics: Aspartic Acid; Cytochromes; NAD; Orotic Acid; Oxidoreductases; Peroxides; Pseudomonas

1967
Metabolism of pyruvate and L-lactate by rat adipose tissue.
    The Journal of biological chemistry, 1969, Apr-25, Volume: 244, Issue:8

    Topics: Acetoacetates; Adipose Tissue; Animals; Aspartic Acid; Butyrates; Carbon Dioxide; Carbon Isotopes; Cytoplasm; Deficiency Diseases; Diet; Dietary Fats; Epididymis; Epinephrine; Fasting; Fatty Acids; Glucose; Glutamates; Glycerol; Hydroxybutyrates; Keto Acids; Ketoglutaric Acids; Lactates; Lipids; Malates; Male; Mitochondria; NAD; Oxaloacetates; Propionates; Pyruvates; Rats; Stimulation, Chemical

1969
Relation of fatty acid oxidation tgluconeogenesis: effect of pentenoic acid.
    Life sciences, 1968, Oct-15, Volume: 7, Issue:20

    Topics: Acetoacetates; Alanine; Animals; Aspartic Acid; Ethanol; Fatty Acids; Gluconeogenesis; Hydroxybutyrates; Hypoglycemic Agents; In Vitro Techniques; Linoleic Acids; Liver; NAD; Oxidation-Reduction; Perfusion; Rats; Valerates

1968
Regulation of the activity of L-aspartate beta-decarboxylase by a novel allosteric mechanism.
    Biochemistry, 1969, Volume: 8, Issue:4

    Topics: Alanine; Alcaligenes; Aspartic Acid; Binding Sites; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chromatography, Gel; Ketoglutaric Acids; Kinetics; L-Lactate Dehydrogenase; Malate Dehydrogenase; Models, Biological; NAD; Pyruvates; Spectrum Analysis

1969
An enzymatic method for the measurement of asparagine and a new assay of asparaginase activity.
    The Journal of laboratory and clinical medicine, 1969, Volume: 74, Issue:3

    Topics: Antineoplastic Agents; Asparaginase; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Chemical Phenomena; Chemistry; Escherichia coli; Humans; Indicators and Reagents; Ketoglutaric Acids; Malate Dehydrogenase; Methods; NAD

1969
[Research on the regulation of carbohydrate metabolism in vivo. I. Action of ethionine].
    Bulletin de la Societe de chimie biologique, 1969, Jun-04, Volume: 51, Issue:1

    Topics: Acetoacetates; Adenine Nucleotides; Animals; Aspartic Acid; Carbohydrate Metabolism; Citrates; Citric Acid Cycle; Ethionine; Female; Glycogen; Glycolysis; Hydroxybutyrates; Lactates; Liver; Malates; Mitochondria, Liver; NAD; Pyruvates; Rats

1969
[Regulation of carbohydrate metabolism in vivo. II. Action of ethanol].
    Bulletin de la Societe de chimie biologique, 1969, Sep-18, Volume: 51, Issue:4

    Topics: Acetoacetates; Animals; Aspartic Acid; Carbohydrate Metabolism; Citrates; Ethanol; Female; Glutamates; Hydroxybutyrates; Keto Acids; Ketoglutaric Acids; Lactates; Liver; Liver Glycogen; Malates; Mitochondria, Liver; NAD; Pyruvates; Rats

1969
Control of citric acid cycle activity in rat heart mitochondria.
    The Journal of biological chemistry, 1970, Jan-10, Volume: 245, Issue:1

    Topics: Acetoacetates; Adenine Nucleotides; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; Citrates; Citric Acid Cycle; Fumarates; Hydroxybutyrates; Ketoglutaric Acids; Kinetics; Malates; Mitochondria, Muscle; Myocardium; NAD; Oxygen Consumption; Pyruvates; Rats; Succinates

1970
Demonstration in vitro of competition between added NADH and glutamate for oxidation by liver mitochondria.
    Biochimica et biophysica acta, 1970, Jan-13, Volume: 197, Issue:1

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Depression, Chemical; Glutamates; In Vitro Techniques; Malate Dehydrogenase; Mitochondria, Liver; NAD; Oxygen Consumption; Pyruvates; Rabbits; Stimulation, Chemical

1970
Regulatory characteristics of the diphosphopyridine nucleotide-specific malic enzyme of Escherichia coli.
    The Journal of biological chemistry, 1970, Mar-10, Volume: 245, Issue:5

    Topics: Adenosine Triphosphate; Aspartic Acid; Binding Sites; Calcium Phosphates; Chemical Precipitation; Chromatography, DEAE-Cellulose; Coenzyme A; Enzyme Activation; Escherichia coli; Ethanol; Hydrogen-Ion Concentration; Kinetics; Malate Dehydrogenase; Methods; NAD; Nucleotides; Quaternary Ammonium Compounds; Sulfates

1970
Transfer of carbon and hydrogen across the mitochondrial membrane in the control of gluconeogenesis.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1970, Volume: 351, Issue:3

    Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Gluconeogenesis; Glyceraldehyde-3-Phosphate Dehydrogenases; Lactates; Malates; Mitochondria, Liver; NAD; Pyruvates; Rats

1970
Effects of ischaemia on metabolite concentrations in rat liver.
    The Biochemical journal, 1970, Volume: 117, Issue:1

    Topics: Acetoacetates; Adenine Nucleotides; Alanine; Ammonia; Animals; Aspartic Acid; Cycloserine; Freezing; Glutamate Dehydrogenase; Glutamates; Glutamine; Glutarates; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Ischemia; Kinetics; Lactates; Liver; Liver Circulation; Malates; Male; Mitochondria, Liver; NAD; Pyruvates; Rats

1970
Studies on the de novo biosynthesis of NAD in Escherichia coli. I. Labelling patterns from precursors.
    Biochimica et biophysica acta, 1970, Nov-24, Volume: 222, Issue:2

    Topics: Aspartic Acid; Carbon Isotopes; Escherichia coli; Glucose; Glycerol; NAD; Pyridines

1970
Interrelationships between malate-aspartate shuttle and citric acid cycle in rat heart mitochondria.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:2

    Topics: Adenine Nucleotides; Animals; Aspartic Acid; Carnitine; Citric Acid Cycle; Coenzyme A; Fluorometry; Glutamates; In Vitro Techniques; Ketoglutaric Acids; Lactates; Malates; Mitochondria; Myocardium; NAD; Oligomycins; Oxaloacetates; Oxidation-Reduction; Oxygen Consumption; Polarography; Rats

1971
Possible regulatory factors for pyruvate carboxylase with particular reference to enzyme from chicken liver.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:2

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Binding Sites; Calcium; Carbon Dioxide; Chemical Phenomena; Chemistry; Chickens; Coenzyme A; Gluconeogenesis; Glycerol; Hydrogen-Ion Concentration; Kinetics; Ligases; Liver; Magnesium; NAD; Oxaloacetates; Oxidation-Reduction; Potassium; Pyruvates; Quaternary Ammonium Compounds; Species Specificity; Sulfates; Temperature

1971
Glutamate dehydrogenase from pea roots: purification and properties of the enzyme.
    Canadian journal of biochemistry, 1971, Volume: 49, Issue:1

    Topics: Alanine; Amination; Amino Acid Oxidoreductases; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Gel; Deamination; Dialysis; Dioxins; Edetic Acid; Electrophoresis; Enzyme Activation; Glutamate Dehydrogenase; Glutamates; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Molecular Weight; NAD; Plants; Quaternary Ammonium Compounds

1971
Threonine-sensitive aspartokinase-homoserine dehydrogenase of Escherichia coli K 12. Reaction with 6-mercapto-9- -D-ribofuranosylpurine 5'-triphosphate.
    Biochemistry, 1971, Jul-06, Volume: 10, Issue:14

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Alcohol Oxidoreductases; Aminobutyrates; Aspartic Acid; Benzoates; Binding Sites; Catalysis; Chromatography, Gel; Circular Dichroism; Electrophoresis; Escherichia coli; Hydrogen-Ion Concentration; Hydroxybutyrates; Kinetics; Mathematics; Mercaptoethanol; Molecular Weight; NAD; Paper; Phosphotransferases; Spectrophotometry; Sulfhydryl Compounds; Sulfhydryl Reagents; Threonine; Tritium; Tromethamine; Ultraviolet Rays

1971
Role of tyrosine in the substrate binding site of mitochondrial L-malate dehydrogenase from bovine heart muscle.
    Biochemistry, 1971, Jul-20, Volume: 10, Issue:15

    Topics: Acetates; Acylation; Animals; Aspartic Acid; Binding Sites; Carbon Isotopes; Carboxylic Acids; Catalysis; Cattle; Chemical Phenomena; Chemistry; Chlorides; Cysteine; Dicarboxylic Acids; Enzyme Activation; Fumarates; Glutamates; Hydrogen-Ion Concentration; Hydroxylamines; Imidazoles; Kinetics; Malate Dehydrogenase; Malates; Mercuribenzoates; Methane; Mitochondria, Muscle; Myocardium; NAD; Spectrophotometry; Sulfates; Sulfonic Acids; Tyrosine

1971
Regulation of gluconeogenesis during exposure of young rats to hypoxic conditions.
    The Biochemical journal, 1971, Volume: 121, Issue:2

    Topics: Acetoacetates; Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspartic Acid; Gluconeogenesis; Glucose; Glycogen; Hydroxybutyrates; Hypoxia; Lactates; Liver; Mitochondria, Liver; NAD; Pyruvates; Rats; Serine; Time Factors

1971
[Current views on the therapy of hepatic coma].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Apr-15, Volume: 25, Issue:8

    Topics: Acute Kidney Injury; Adolescent; Amino Acids; Ammonia; Anti-Bacterial Agents; Arginine; Aspartic Acid; Coenzyme A; Diet Therapy; Exchange Transfusion, Whole Blood; Glutamates; Hepatic Encephalopathy; Humans; Malates; Male; NAD; Ornithine; Prednisone; Prognosis; Renal Dialysis; Thiamine Pyrophosphate; Thioctic Acid; Vasopressins

1970
Genetic and physiological control of serine and glycine biosynthesis in Saccharomyces.
    Journal of bacteriology, 1972, Volume: 109, Issue:1

    Topics: Acetates; Alanine; Ammonium Sulfate; Aspartic Acid; Carbon Isotopes; Cell-Free System; Chemical Precipitation; Chromatography, Paper; Culture Media; Fluorides; Genetics, Microbial; Glucose; Glutamates; Glycerolphosphate Dehydrogenase; Glycerophosphates; Glycine; Glycolysis; Glyoxylates; Isocitrates; Lyases; Mutation; NAD; Oxidative Phosphorylation; Saccharomyces; Serine; Spectrophotometry; Transferases

1972
Pyruvate metabolism in the lobster nerve as affected by the partial pressure of carbon dioxide: observations on the synthesis of acetylcholine and on metabolic compartmentation.
    Journal of neurochemistry, 1972, Volume: 19, Issue:2

    Topics: Acetylcholine; Alanine; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Citrates; Glutamates; Isocitrate Dehydrogenase; Malates; NAD; Nephropidae; Peripheral Nerves; Pyruvates

1972
Studies on the biosynthesis of NAD in Escherichia coli. 3. Precursors of quinolinic acid in vitro.
    Biochimica et biophysica acta, 1972, Apr-21, Volume: 264, Issue:2

    Topics: Acetates; Aspartic Acid; Carbon Isotopes; Drug Stability; Escherichia coli; Formates; Fructosephosphates; Genetics, Microbial; Glyceric Acids; Glycerol; Glycerophosphates; Hot Temperature; Hydrogen-Ion Concentration; Ligases; Mutation; NAD; Organophosphorus Compounds; Pyridines; Pyridoxal Phosphate; Pyridoxamine; Succinates; Tritium

1972
Ethanol and the metabolic interrelations of carbohydrates and amino acids in brain preparations.
    Biochemical pharmacology, 1972, Apr-15, Volume: 21, Issue:8

    Topics: Adenosine Triphosphate; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbohydrate Metabolism; Carbon Isotopes; Ethanol; Glucose; Glucosephosphates; Glutamine; Hexokinase; In Vitro Techniques; Lactates; NAD; Pyruvates; Rats; Rats, Inbred Strains

1972
Stereospecificity of the dihydroorotate-dehydrogenase reaction.
    European journal of biochemistry, 1972, Oct-17, Volume: 30, Issue:1

    Topics: Asparagine; Aspartic Acid; Bacteria; Benzyl Compounds; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Thin Layer; Deuterium; Esters; Ethanol; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; NAD; Orotic Acid; Oxidation-Reduction; Oxidoreductases; Structure-Activity Relationship

1972
Effect of chronic ethanol ingestion on mitochondrial permeability and the transport of reducing equivalents.
    Biochemical and biophysical research communications, 1972, Nov-01, Volume: 49, Issue:3

    Topics: Acetone; Animals; Aspartate Aminotransferases; Aspartic Acid; Biological Transport; Diet; Ethanol; Fatty Acids, Nonesterified; Glycerolphosphate Dehydrogenase; Ketoglutaric Acids; Malate Dehydrogenase; Male; Mitochondria, Liver; Mitochondrial Swelling; NAD; Organophosphorus Compounds; Permeability; Quaternary Ammonium Compounds; Rats; Trioses

1972
Comparative transport activity of intact cells, membrane vesicles, and mesosomes of Bacillus licheniformis.
    Journal of bacteriology, 1973, Volume: 113, Issue:1

    Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Biological Transport, Active; Carbon Isotopes; Cell Fractionation; Cell Membrane; Cell Membrane Permeability; Centrifugation, Density Gradient; Chromatography, Paper; Culture Media; Glutamates; Histidine; Inclusion Bodies; Light; Lysine; NAD; Sodium; Stereoisomerism; Succinates; Vitamin K

1973
Recognition of a gene involved in the regulation of nicotinamide adenine dinucleotide biosynthesis.
    Journal of bacteriology, 1973, Volume: 114, Issue:1

    Topics: Alleles; Aspartic Acid; Carbon Isotopes; Chromosome Mapping; Culture Media; Escherichia coli; Genes, Regulator; Genetic Complementation Test; Genotype; Mutation; NAD; Pyridines; Recombination, Genetic; Transduction, Genetic; Trioses

1973
[The effect of L-aspartic acid in isoproterenol necrosis of cardiac muscle].
    Kardiologiia, 1972, Volume: 12, Issue:12

    Topics: Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Heart Diseases; Isoenzymes; Isoproterenol; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Mitochondria, Muscle; Myocardium; NAD; Necrosis; Oxidative Phosphorylation; Oxygen Consumption; Phosphates; Rabbits

1972
Studies on the de novo biosynthesis of NAD in Escherichia coli. V. Properties of the quinolinic acid synthetase system.
    Biochimica et biophysica acta, 1973, Apr-28, Volume: 304, Issue:2

    Topics: Aspartic Acid; Carbon Isotopes; Chromatography, Gel; Drug Stability; Escherichia coli; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Molecular Weight; Multienzyme Complexes; Mutation; NAD; Organophosphorus Compounds; Pyridines; Trioses

1973
The oxidation of acetate by liver mitochondria.
    FEBS letters, 1973, Jan-15, Volume: 29, Issue:2

    Topics: Acetates; Acetoacetates; Adenine Nucleotides; Animals; Arsenic; Aspartic Acid; Carbon Isotopes; Glutamates; Hydroxybutyrates; Ketoglutaric Acids; Malates; Mitochondria, Liver; NAD; Oxygen Consumption; Rats; Succinates

1973
Effect of acetaldehyde on activity of shuttles for the transport of reducing equivalents into the mitochondria.
    FEBS letters, 1973, Nov-15, Volume: 37, Issue:1

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Aspartic Acid; Biological Transport; Ethanol; Fatty Acids; Glycerophosphates; Malates; Mitochondria, Liver; NAD; Oxidation-Reduction; Rats

1973
Metabolite synthesis by rat liver cells and rat liver mitochondria.
    Canadian journal of biochemistry, 1973, Volume: 51, Issue:12

    Topics: Acetates; Animals; Aspartic Acid; Carbon Radioisotopes; Cell Membrane; Citrates; Cytological Techniques; Cytoplasm; Evaluation Studies as Topic; Fatty Acids; Glutamates; Hydroxybutyrates; Ketoglutaric Acids; Liver; Malates; Microbial Collagenase; Mitochondria, Liver; NAD; Oxidation-Reduction; Rats

1973
De novo biosynthesis of nicotinamide adenine dinucleotide in Escherichia coli: excretion of quinolinic acid by mutants lacking quinolinate phosphoribosyl transferase.
    Journal of bacteriology, 1972, Volume: 111, Issue:1

    Topics: Amino Acids; Aspartic Acid; Culture Media; Dicarboxylic Acids; Enzyme Repression; Escherichia coli; Feedback; Glycerol; Hydrogen-Ion Concentration; Mutation; NAD; Nicotinic Acids; Pentosyltransferases; Pyridines; Ribose

1972
Effects of pyrazole, 4-bromopyrazole and 4-methylpyrazole on mitochondrial function.
    Biochemical pharmacology, 1974, Jan-15, Volume: 23, Issue:2

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Ascorbic Acid; Aspartic Acid; Citrates; Electron Transport; Electron Transport Complex IV; Fatty Acids; Glutamates; Glycerophosphates; Ketoglutaric Acids; Malates; Mitochondria, Liver; Mitochondrial Swelling; NAD; Oxidative Phosphorylation; Oxygen Consumption; Phosphates; Phosphorus Radioisotopes; Pyrazoles; Rats; Succinate Dehydrogenase; Succinates

1974
The effect of porta-caval anastomosis upon the energy state and upon acid-base parameters of the rat brain.
    Journal of neurochemistry, 1974, Volume: 22, Issue:3

    Topics: Acid-Base Equilibrium; Ammonia; Animals; Aspartic Acid; Brain; Brain Stem; Carbon Dioxide; Cerebellum; Frontal Lobe; Glucose; Glucosephosphates; Glutamates; Hydrogen-Ion Concentration; Ketoglutaric Acids; L-Lactate Dehydrogenase; Malate Dehydrogenase; Male; Microelectrodes; NAD; Organ Specificity; Oxidation-Reduction; Oxygen; Phosphates; Portacaval Shunt, Surgical; Rats; Time Factors

1974
Oxidation of reduced nicotinamide-adenine dinucleotide by the malate-aspartate shuttle in Ehrlich ascites tumour cells.
    Biochimica et biophysica acta, 1974, Mar-26, Volume: 333, Issue:3

    Topics: Acetates; Animals; Antimycin A; Aspartate Aminotransferases; Aspartic Acid; Benzimidazoles; Carcinoma, Ehrlich Tumor; Electron Transport; Energy Transfer; Hydroxylamines; Kinetics; Lactates; Malates; Mice; Mitochondria; NAD; Nitrogen; Oligomycins; Oxidation-Reduction; Rotenone; Time Factors

1974
Recommended methods for the determination of four enzymes in blood.
    Scandinavian journal of clinical and laboratory investigation, 1974, Volume: 33, Issue:4

    Topics: Alanine; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Aspartic Acid; Buffers; Catalysis; Edetic Acid; Ethanolamines; Humans; Hydrochloric Acid; Indicators and Reagents; Ketoglutaric Acids; L-Lactate Dehydrogenase; Magnesium Oxide; Malate Dehydrogenase; Methods; NAD; Phosphoric Acids; Pyridoxal; Pyruvates; Scandinavian and Nordic Countries; Swine; Temperature; Tromethamine

1974
Effects of clofibrate on mitochondrial function.
    Biochemical pharmacology, 1974, Jul-15, Volume: 23, Issue:14

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Ascorbic Acid; Aspartic Acid; Calcium; Clofibrate; Energy Metabolism; Ethanol; Glycerophosphates; In Vitro Techniques; Ketoglutaric Acids; Malates; Membranes; Mitochondria, Liver; NAD; Oxidative Phosphorylation; Oxygen Consumption; Permeability; Phosphorus Radioisotopes; Rats; Succinates

1974
The kinetics of NAD-linked isocitrate dehydrogenase from calf heart.
    Biochimica et biophysica acta, 1974, Nov-25, Volume: 370, Issue:1

    Topics: Adenosine Diphosphate; Animals; Aspartic Acid; Binding Sites; Calorimetry; Cattle; Glutamates; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Manganese; Mathematics; Myocardium; NAD; Protein Binding; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics

1974
A possible role of the glycerol phosphate cycle in cyclic AMP-stimulated gluconeogenesis from lactate in perfused rat livers.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1974, Volume: 355, Issue:3

    Topics: Animals; Aspartic Acid; Bucladesine; Carbon Radioisotopes; Cytosol; Fasting; Gluconeogenesis; Glucose; Glutamates; Glycerolphosphate Dehydrogenase; Glycerophosphates; Glycogen; In Vitro Techniques; Ketone Bodies; Lactates; Liver; Malates; Male; NAD; Perfusion; Pyruvates; Rats; Stimulation, Chemical; Thyroxine; Time Factors; Triiodothyronine; Tritium

1974
[Participation of nicotinamide-hypoxanthine-dinucleotide (deamino-NAD) in nitrogen and energy metabolism].
    Voprosy biokhimii mozga, 1973, Volume: 8

    Topics: Adenosine Monophosphate; Alcohol Oxidoreductases; Ammonia; Animals; Antimycin A; Aspartic Acid; Brain; Brain Chemistry; Cell Nucleus; Deamination; Energy Metabolism; Glutamates; Glycolysis; Ketoglutaric Acids; Microsomes; Mitochondria; Mitochondria, Liver; NAD; Niacinamide; Nitrogen; Nitrogen Isotopes; Nucleotides; Oxidative Phosphorylation; Rabbits; Rats; Rotenone; Subcellular Fractions; Succinates; Time Factors; Transaminases; Yeasts

1973
Glutamate and aspartate transport in rat brain mitochondria.
    The Biochemical journal, 1974, Volume: 140, Issue:2

    Topics: Animals; Aspartic Acid; Biological Transport; Brain; Glutamates; Glutaminase; Glutamine; In Vitro Techniques; Kidney; Malates; Mitochondria; Mitochondria, Liver; NAD; Osmosis; Potassium; Quaternary Ammonium Compounds; Rats; Swine; Valinomycin

1974
Functional significance of the malate-aspartate shuttle for the oxidation of cytoplasmic reducing equivalents in rat heart.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Biological Transport, Active; Cytoplasm; Electron Transport; Flavoproteins; Hydrogen-Ion Concentration; Lactates; Malates; Male; Mitochondria, Muscle; Models, Biological; Myocardium; NAD; Organophosphorus Compounds; Pyruvates; Rats

1972
Fluorometric determination of aspartate, glutamate, and gamma-aminobutyrate in nerve tissue using enzymic methods.
    Analytical biochemistry, 1966, Volume: 15, Issue:3

    Topics: Aminobutyrates; Animals; Aspartic Acid; Cats; Fluorometry; Glutamates; In Vitro Techniques; Microchemistry; NAD; NADP; Nerve Tissue; Spinal Cord

1966
Mechanism for the stimulation of gluconeogenesis by fatty acids in perfused rat liver.
    Proceedings of the National Academy of Sciences of the United States of America, 1966, Volume: 56, Issue:1

    Topics: Animals; Aspartic Acid; Citrates; Citric Acid Cycle; Coenzyme A; Gluconeogenesis; Glutamates; In Vitro Techniques; Ketoglutaric Acids; Ketone Bodies; Liver; Malates; NAD; NADP; Oleic Acids; Oxaloacetates; Perfusion; Rats

1966
The metabolic fate of the products of citrate cleavage. Adenosine triphosphate-citrate lyase and nicotinamide-adenine dinucleotide phosphate-linked malate dehydrogenase in foetal and adult liver from ruminants and non-ruminants.
    The Biochemical journal, 1968, Volume: 108, Issue:5

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Cattle; Citrates; Fatty Acids; Female; Fetus; Glucose; Glutamates; In Vitro Techniques; Lipids; Liver; Lyases; Malate Dehydrogenase; Male; NAD; NADP; Pregnancy; Rats

1968
Control of gluconeogenesis in biotin-deficient rat liver.
    Archives of biochemistry and biophysics, 1969, Volume: 129, Issue:1

    Topics: Alanine; Animals; Aspartic Acid; Avitaminosis; Bicarbonates; Biotin; Blood Glucose; Carbon Isotopes; Fatty Acids, Nonesterified; Gluconeogenesis; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerol; Lactates; Ligases; Liver; Liver Glycogen; Male; NAD; NADP; Pyruvates; Rats; Succinates; Time Factors

1969
Studies on the catalytic and regulatory properties of homoserine dehydrogenase of Zea mays roots.
    Biochimica et biophysica acta, 1969, Feb-11, Volume: 171, Issue:2

    Topics: Alcohol Oxidoreductases; Aminobutyrates; Aspartic Acid; Binding Sites; Cysteine; Hydroxybutyrates; Kinetics; NAD; NADP; Plants; Serine; Zea mays

1969
Human glucose 6-phosphate dehydrogenase: purification and characterization of Negro type variant (A+) and comparison with normal enzyme (B+).
    Biochemical genetics, 1967, Volume: 1, Issue:2

    Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Black People; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Erythrocytes; Glucosephosphate Dehydrogenase; Guanidines; Humans; Hydrogen-Ion Concentration; Immune Sera; Immunodiffusion; Isoenzymes; Kinetics; Magnesium; Male; Molecular Weight; NAD; NADP; Rabbits; Ultracentrifugation

1967
A study of the metabolism of L-alpha gamma-diaminobutyric acid in a Xanthomonas species.
    The Biochemical journal, 1969, Volume: 114, Issue:1

    Topics: Aminobutyrates; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Hydrogen-Ion Concentration; NAD; Oxaloacetates; Transaminases; Xanthomonas

1969
[Determination of substrate concentrations and cofactors in rat liver].
    Archives des sciences physiologiques, 1969, Volume: 23, Issue:4

    Topics: Acetoacetates; Alanine; Animals; Aspartic Acid; Citrates; Citric Acid Cycle; Glutamates; Glycerophosphates; Hydroxybutyrates; Ketoglutaric Acids; Lactates; Liver; Malates; NAD; NADP; Oxaloacetates; Pyruvates; Rats; Trioses

1969
Intracellular localization of enzymes in leaves and chloroplast membrane permeability to compounds involved in amino acid syntheses.
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1969, Volume: 24, Issue:9

    Topics: Alanine; Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Carbon Dioxide; Chloroplasts; Glutamate Dehydrogenase; Glutamates; Glutathione Reductase; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycine; Isocitrate Dehydrogenase; Malate Dehydrogenase; NAD; NADP; Nicotiana; Oxidoreductases; Plants; Plants, Edible; Plants, Toxic; Pyruvate Kinase; Serine

1969
Regulation of the biosynthesis of amino acids of the aspartate family in Coliform bacteria and Pseudomonads.
    Journal of bacteriology, 1969, Volume: 99, Issue:3

    Topics: Aeromonas; Alcohol Oxidoreductases; Aspartic Acid; Enterobacteriaceae; NAD; NADP; Phosphotransferases; Pseudomonas

1969
Nitrogen metabolism in the perfused rat liver.
    Biochimica et biophysica acta, 1970, Oct-27, Volume: 222, Issue:1

    Topics: Alanine; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Glutamate Dehydrogenase; Glutamates; Glutamine; Hydroxybutyrate Dehydrogenase; Liver; NAD; NADP; Nitrogen; Perfusion; Rats; Stimulation, Chemical; Urea

1970
[Metabolic disorders induced by an acute dose of ethanol in the liver of the adrenalectomized rat].
    Food and cosmetics toxicology, 1970, Volume: 8, Issue:5

    Topics: Adrenal Glands; Adrenalectomy; Animals; Aspartic Acid; Ethanol; Glutamates; Glycerophosphates; Hydrocortisone; Hydroxybutyrates; Injections, Intramuscular; Injections, Intraperitoneal; Liver; Malates; Male; NAD; NADP; Phosphates; Rats; Time Factors

1970
[Effects of an intraperitoneal injection of fructose on the hepatic metabolism of the rat].
    Enzymologia biologica et clinica, 1970, Volume: 11, Issue:6

    Topics: Alanine; Animals; Aspartic Acid; Citrates; Citric Acid Cycle; Fasting; Fructose; Glutamates; Glycolysis; Injections, Intraperitoneal; Ketoglutaric Acids; Lipids; Liver; Malates; Male; NAD; NADP; Oxaloacetates; Rats; Stimulation, Chemical; Time Factors; Transaminases

1970
Physiological functions of NAD- and NADP-linked malic enzymes in Escherichia coli.
    Biochemical and biophysical research communications, 1971, May-21, Volume: 43, Issue:4

    Topics: Acetates; Aspartic Acid; Binding Sites; Carbon Isotopes; Cell-Free System; Centrifugation; Coenzyme A; Culture Media; Depression, Chemical; Enzyme Induction; Enzyme Repression; Escherichia coli; Fatty Acids; Glucose; Glutamates; Glycerol; Glycolysis; Lactates; Malate Dehydrogenase; Malates; Models, Biological; Models, Chemical; NAD; NADP; Pyruvates; Spectrophotometry; Stimulation, Chemical; Succinates; Vibration

1971
Conversion of the alpha-hydroxy and alpha-keto analogues of methionine to methionine by cell-free extracts of adult female Ascaris suum.
    The Journal of parasitology, 1971, Volume: 57, Issue:4

    Topics: Ascaris; Asparagine; Aspartic Acid; Butyrates; Cell-Free System; Female; Glutamates; Glutamine; Methionine; NAD; NADP; Oxidation-Reduction; Proteins

1971
Lack of correlation between cyanide-binding spectrum and fatty acid desaturase activity in liver microsomes.
    Biochemical and biophysical research communications, 1971, Aug-06, Volume: 44, Issue:3

    Topics: Adipose Tissue; Animals; Aspartic Acid; Carbon Isotopes; Coenzyme A; Cyanides; Cytochromes; Dietary Carbohydrates; Epididymis; Fasting; Fatty Acids; Kinetics; Male; Microsomes; Microsomes, Liver; NAD; NADP; Oxidoreductases; Oxygen; Potassium; Protein Binding; Rats; Spectrophotometry; Stearic Acids; Threonine; Time Factors

1971
Enzyme activities in the anterior horn of spinal cord after , -iminodipropionitrile.
    Experimental neurology, 1971, Volume: 33, Issue:2

    Topics: Age Factors; Animals; Aspartate Aminotransferases; Aspartic Acid; Axons; Gluconates; Glucosephosphate Dehydrogenase; Glucosephosphates; Isocitrate Dehydrogenase; Isocitrates; Male; Motor Neurons; Movement Disorders; NAD; NADP; Neurons, Afferent; Nitriles; Phosphogluconate Dehydrogenase; Rats; Spinal Cord

1971
Inorganic nitrogen assimilation in yeasts: alteration in enzyme activities associated with changes in cultural conditions and growth phase.
    Journal of bacteriology, 1972, Volume: 109, Issue:1

    Topics: Alanine; Alanine Transaminase; Amino Acid Oxidoreductases; Amino Acids; Ammonium Sulfate; Aspartate Aminotransferases; Aspartic Acid; Cell-Free System; Culture Media; Electrophoresis, Disc; Genetics, Microbial; Glucose; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Hydro-Lyases; Hydrogen-Ion Concentration; Lyases; Mutation; NAD; NADP; Nitrogen; Saccharomyces; Saccharomyces cerevisiae; Spectrophotometry; Threonine; Transaminases

1972
[Glutamate cycle, first step of nitrogen metabolism in Bacillus megaterium].
    European journal of biochemistry, 1972, May-23, Volume: 27, Issue:2

    Topics: Alanine; Allosteric Regulation; Amino Acid Oxidoreductases; Ammonia; Aspartic Acid; Bacillus megaterium; Enzyme Repression; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Ketoglutaric Acids; Lyases; Mutation; NAD; NADP; Nitrogen; Oxaloacetates; Oxidoreductases; Pyruvates; Transaminases

1972
Studies on regulatory functions of malic enzymes. I. Metabolic functions of NAD- and NADP-linked malic enzymes in Escherichia coli.
    Journal of biochemistry, 1972, Volume: 71, Issue:6

    Topics: Acetates; Aspartic Acid; Carbon Isotopes; Cell-Free System; Coenzyme A; Escherichia coli; Fatty Acids; Glucose; Glutamates; Glycerol; Lactates; Malate Dehydrogenase; Malates; NAD; NADP; Pyruvates; Succinates

1972
Freeze-blowing: a new technique for the study of brain in vivo.
    Journal of neurochemistry, 1973, Volume: 20, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aspartic Acid; Brain; Brain Chemistry; Equipment and Supplies; Freezing; Glucose; Iron; Lactates; Malates; Male; Methods; Microwaves; NAD; NADP; Oxidation-Reduction; Phosphates; Phosphocreatine; Pressure; Pyruvates; Rats

1973
Effects of thyroid hormone on mitochondrial activity in lipemic BHE rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1981, Volume: 166, Issue:3

    Topics: Animals; Aspartic Acid; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Glycerophosphates; Malates; Male; Mitochondria, Liver; NAD; Oxygen Consumption; Rats; Rats, Inbred Strains; Thyroxine

1981
Coupling between reduced nicotinamide adenine dinucleotide oxidation and metabolite transport in renal brush border membrane vesicles.
    Biochemistry, 1980, Oct-14, Volume: 19, Issue:21

    Topics: Animals; Aspartic Acid; Biological Transport, Active; Cell Membrane; In Vitro Techniques; Kidney Tubules, Proximal; Microvilli; NAD; Oxidation-Reduction; Potassium; Protons; Rats; Sodium

1980
The stimulus-secretion coupling of amino acid-induced insulin release: metabolism of L-asparagine in pancreatic islets.
    Archives of biochemistry and biophysics, 1984, Feb-15, Volume: 229, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Asparaginase; Asparagine; Aspartic Acid; Cytosol; Fatty Acids; Islets of Langerhans; Kinetics; Mitochondria; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats

1984
Action of L-aspartic, methyl aspartic and acetyl aspartic acids on GABA transaminase histochemical activity in nervous tissue.
    Cellular and molecular biology, 1984, Volume: 30, Issue:6

    Topics: 4-Aminobutyrate Transaminase; Animals; Aspartic Acid; Brain; N-Methylaspartate; NAD; NADP; Rats; Rats, Inbred Strains

1984
Present status in searching for biochemical markers among laboratory inbred rat strains (Rattus norvegicus).
    Folia biologica, 1980, Volume: 26, Issue:2

    Topics: Acid Phosphatase; Adenylyl Cyclases; Alanine; Alanine Transaminase; Alleles; Animals; Aspartate Aminotransferases; Aspartic Acid; Dihydrolipoamide Dehydrogenase; Erythrocytes; Esterases; Glucose-6-Phosphate Isomerase; Glucosephosphates; NAD; Peptide Hydrolases; Phosphoglucomutase; Phosphogluconate Dehydrogenase; Proteins; Rats; Rats, Inbred Strains; Uridine Kinase; Uridine Monophosphate

1980
Mitochondrial membrane potential, transmembrane difference in the NAD+ redox potential and the equilibrium of the glutamate-aspartate translocase in the isolated perfused rat heart.
    Biochimica et biophysica acta, 1983, Dec-30, Volume: 725, Issue:3

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport, Active; Glutamates; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Heart; Myocardium; NAD; Oxidation-Reduction; Rats

1983
Modification of aspartate before its condensation with dihydroxyacetone phosphate during quinolinic acid formation in Escherichia coli.
    Journal of bacteriology, 1980, Volume: 141, Issue:2

    Topics: Aspartic Acid; Cell-Free System; Dihydroxyacetone Phosphate; Escherichia coli; Fructosediphosphates; Histidine; Mutation; NAD; Proline; Pyridines; Quinolinic Acids; Trioses

1980
Free amino acids in the brain of ethanol treated rats.
    Substance and alcohol actions/misuse, 1982, Volume: 3, Issue:1-2

    Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport; Brain Chemistry; Ethanol; gamma-Aminobutyric Acid; Glutamates; Glutamine; Male; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains

1982
Rapid oxidation of NADPH via the reconstituted malate-aspartate shuttle in systems containing mitochondrial and soluble fractions of rat liver: implications for ethanol metabolism.
    Biochemical pharmacology, 1982, Sep-01, Volume: 31, Issue:17

    Topics: Animals; Aspartic Acid; Ethanol; Female; In Vitro Techniques; Liver; Malates; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Proteins; Rats; Rats, Inbred Strains

1982
A straightforward method for the simultaneous preparation of radiolabeled L-dihydroörotic and N-carbamyl-L-aspartic acids.
    Analytical biochemistry, 1981, Volume: 111, Issue:1

    Topics: Aspartic Acid; Carbon Radioisotopes; Chromatography, Ion Exchange; Electrophoresis; Isotope Labeling; NAD; Orotic Acid

1981
Reducing equivalent shuttles in developing porcine myocardium: enhanced capacity in the newborn heart.
    Pediatric research, 1995, Volume: 38, Issue:2

    Topics: Adenosine Triphosphate; Aerobiosis; Animals; Animals, Newborn; Aspartic Acid; Biological Transport; Glycerophosphates; Heart; Malates; Mitochondria, Heart; Myocardial Contraction; NAD; Oxidation-Reduction; Swine

1995
Roles of histidine-194, aspartate-163, and a glycine-rich sequence of NAD(P)H:quinone oxidoreductase in the interaction with nicotinamide coenzymes.
    Archives of biochemistry and biophysics, 1995, Nov-10, Volume: 323, Issue:2

    Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Consensus Sequence; DNA Primers; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Rats; Structure-Activity Relationship; Vitamin K

1995
Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes.
    European journal of biochemistry, 1995, Jul-15, Volume: 231, Issue:2

    Topics: 2,4-Dinitrophenol; Adenine Nucleotides; Animals; Aspartic Acid; Caprylates; Cell Separation; Dihydroxyacetone; Dinitrophenols; Electron Transport; Fatty Acids; Glucose; Lactates; Lactic Acid; Liver; Malates; Male; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1995
Substrate-induced acceleration of N-ethylmaleimide reaction with the Cys-65 mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter depends on the interaction of Asp-66 with the substrate.
    FEBS letters, 1995, Mar-27, Volume: 362, Issue:1

    Topics: Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Base Sequence; Cell Membrane; Cysteine; DNA Transposable Elements; Escherichia coli; Ethylmaleimide; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Protein Conformation; Tetracycline

1995
D175 discriminates between NADH and NADPH in the coenzyme binding site of Lactobacillus delbrueckii subsp. bulgaricus D-lactate dehydrogenase.
    Biochemical and biophysical research communications, 1995, Mar-28, Volume: 208, Issue:3

    Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Bacteria; Base Sequence; Binding Sites; Consensus Sequence; Kinetics; L-Lactate Dehydrogenase; Lactobacillus; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oligodeoxyribonucleotides; Point Mutation; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity

1995
The effect of ion pairs on the thermal stability of D-glyceraldehyde 3-phosphate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima.
    Protein engineering, 1994, Volume: 7, Issue:12

    Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Base Sequence; Enzyme Stability; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Gram-Negative Anaerobic Bacteria; Hot Temperature; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Sequence Alignment

1994
Catalytic-rate improvement of a thermostable malate dehydrogenase by a subtle alteration in cofactor binding.
    The Biochemical journal, 1995, Jan-15, Volume: 305 ( Pt 2)

    Topics: Aspartic Acid; Base Sequence; Catalysis; Enzyme Stability; Glutamic Acid; Hot Temperature; Malate Dehydrogenase; Models, Chemical; Molecular Sequence Data; Mutagenesis; Mutation; NAD; Oxaloacetates; Oxidation-Reduction; Protein Conformation; Recombinant Proteins; Solvents; Structure-Activity Relationship; Thermus; Viscosity

1995
Calcium and 2-oxoglutarate-mediated control of aspartate formation by rat heart mitochondria.
    European journal of biochemistry, 1994, Aug-01, Volume: 223, Issue:3

    Topics: Animals; Aspartic Acid; Calcium; Dinitrophenols; Enzyme Activation; Glutamates; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Malates; Membrane Potentials; Mitochondria, Heart; Models, Biological; NAD; Pyruvates; Pyruvic Acid; Rats

1994
The effect of replacing the conserved active-site residues His-264, Asp-312 and Arg-314 on the binding and catalytic properties of Escherichia coli citrate synthase.
    The Biochemical journal, 1994, Jun-15, Volume: 300 ( Pt 3)

    Topics: Anilino Naphthalenesulfonates; Arginine; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Citrate (si)-Synthase; Dithionitrobenzoic Acid; Escherichia coli; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Protein Conformation; Structure-Activity Relationship

1994
A role for Asp-251 in cytochrome P-450cam oxygen activation.
    The Journal of biological chemistry, 1994, Feb-11, Volume: 269, Issue:6

    Topics: Aspartic Acid; Camphor 5-Monooxygenase; Catalysis; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Mixed Function Oxygenases; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Oxygen; Pseudomonas putida; Spectrophotometry, Ultraviolet; Spectrum Analysis; Structure-Activity Relationship

1994
Site-directed mutagenesis of two conserved charged amino acids in the N-terminal region of alpha subunit of E. coli-F(0)F(1).
    FEBS letters, 1996, Mar-11, Volume: 382, Issue:1-2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Arginine; Aspartic Acid; Base Sequence; Cell Membrane; Conserved Sequence; Dicyclohexylcarbodiimide; Escherichia coli; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Proton Pumps; Proton-Translocating ATPases

1996
Switch of coenzyme specificity of mouse lung carbonyl reductase by substitution of threonine 38 with aspartic acid.
    The Journal of biological chemistry, 1997, Jan-24, Volume: 272, Issue:4

    Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Aspartic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Lung; Mice; Mutagenesis, Site-Directed; NAD; NADP; Protein Denaturation; Structure-Activity Relationship; Threonine

1997
Fumarate permeation in normal and acidotic rat kidney mitochondria: fumarate/malate and fumarate/aspartate translocators.
    Biochemical and biophysical research communications, 1998, Feb-24, Volume: 243, Issue:3

    Topics: Acidosis; Adenylosuccinate Lyase; Animals; Aspartic Acid; Biological Transport; Carrier Proteins; Fumarates; Kidney; Malates; Male; Mitochondria; NAD; NADP; Oxaloacetates; Rats; Rats, Wistar

1998
Ontogeny of malate-aspartate shuttle capacity and gene expression in cardiac mitochondria.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Base Sequence; Biological Transport; DNA, Complementary; Down-Regulation; Gene Expression; Malate Dehydrogenase; Malates; Mitochondria, Heart; Molecular Sequence Data; NAD; RNA, Messenger; Swine

1998
Roles of negatively charged surface residues of putidaredoxin in interactions with redox partners in p450cam monooxygenase system.
    Biochimica et biophysica acta, 1998, Jul-28, Volume: 1386, Issue:1

    Topics: Aspartic Acid; Binding Sites; Camphor 5-Monooxygenase; Electricity; Electron Transport; Ferredoxins; Glutamic Acid; Models, Molecular; Mutagenesis, Site-Directed; NAD; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Potentiometry; Protein Binding; Protein Structure, Secondary; Spectrophotometry

1998
Metabolic modulation of cellular redox potential can improve cardiac recovery from ischemia-reperfusion injury.
    International journal of cardiology, 1998, Jul-01, Volume: 65, Issue:2

    Topics: Animals; Aspartic Acid; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; NAD; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Xanthines

1998
Malate-aspartate shuttle, cytoplasmic NADH redox potential, and energetics in vascular smooth muscle.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:8

    Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Biological Transport; Cytoplasm; Energy Metabolism; Glucose; Malates; Mitochondria, Muscle; Muscle Contraction; Muscle, Smooth, Vascular; NAD; Oxidation-Reduction; Oxygen Consumption; Phosphates; Swine

1998
Structural basis of substrate specificity in malate dehydrogenases: crystal structure of a ternary complex of porcine cytoplasmic malate dehydrogenase, alpha-ketomalonate and tetrahydoNAD.
    Journal of molecular biology, 1999, Jan-15, Volume: 285, Issue:2

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Cytoplasm; Histidine; Malate Dehydrogenase; Malonates; Molecular Sequence Data; NAD; Protein Conformation; Protein Structure, Secondary; Substrate Specificity; Swine

1999
Direct measurement of the pKa of aspartic acid 26 in Lactobacillus casei dihydrofolate reductase: implications for the catalytic mechanism.
    Biochemistry, 1999, Jun-22, Volume: 38, Issue:25

    Topics: Apoenzymes; Aspartic Acid; Catalysis; Folic Acid; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Macromolecular Substances; NAD; Tetrahydrofolate Dehydrogenase

1999
A change in reaction specificity of sheep liver serine hydroxymethyltransferase. Induction of NADH oxidation upon mutation of His230 to Tyr.
    European journal of biochemistry, 2000, Volume: 267, Issue:4

    Topics: Amino Acid Substitution; Animals; Aspartate Aminotransferases; Aspartic Acid; Electrons; Free Radical Scavengers; Glycine Hydroxymethyltransferase; Kinetics; Liver; Mannitol; Mutation; NAD; Nitroblue Tetrazolium; Oxidation-Reduction; Recombinant Proteins; Sheep; Spectrophotometry, Ultraviolet; Substrate Specificity; Superoxide Dismutase

2000
Roles of his205, his296, his303 and Asp259 in catalysis by NAD+-specific D-lactate dehydrogenase.
    European journal of biochemistry, 2000, Volume: 267, Issue:6

    Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalysis; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactobacillus; Models, Molecular; Mutagenesis, Site-Directed; NAD; Point Mutation; Recombinant Fusion Proteins; Structure-Activity Relationship

2000
Identification of the enzymatic active site of CD38 by site-directed mutagenesis.
    The Journal of biological chemistry, 2000, Jul-14, Volume: 275, Issue:28

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Affinity Labels; Amino Acid Substitution; Animals; Antigens, CD; Antigens, Differentiation; Aplysia; Aspartic Acid; Azides; Binding Sites; Circular Dichroism; Cloning, Molecular; Crystallography, X-Ray; Humans; Kinetics; Membrane Glycoproteins; Models, Molecular; Mutagenesis, Site-Directed; NAD; NAD+ Nucleosidase; Pichia; Protein Structure, Secondary; Recombinant Proteins

2000
A new class of glutamate dehydrogenases (GDH). Biochemical and genetic characterization of the first member, the AMP-requiring NAD-specific GDH of Streptomyces clavuligerus.
    The Journal of biological chemistry, 2000, Dec-15, Volume: 275, Issue:50

    Topics: Adenosine Monophosphate; Allosteric Site; Amino Acid Sequence; Ammonia; Asparagine; Aspartic Acid; Base Sequence; Carbon; Catalysis; Cell Division; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Evolution, Molecular; Glutamate Dehydrogenase; Glycerol; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Molecular Sequence Data; Molecular Weight; NAD; Nitrogen; Phylogeny; Polymerase Chain Reaction; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Streptomyces; Temperature; Time Factors; Tricarboxylic Acids

2000
Metabolic adaptation of the hypertrophied heart: role of the malate/aspartate and alpha-glycerophosphate shuttles.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:12

    Topics: Adenosine Triphosphate; Animals; Aorta; Aspartic Acid; Atrial Natriuretic Factor; Blotting, Northern; Cardiomegaly; Fatty Acids; Glucose; Glycerophosphates; Immunoblotting; Lactic Acid; Malate Dehydrogenase; Malates; Male; Mitochondria; Models, Biological; Myocardium; NAD; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors

2000
The nicotinamide biosynthetic pathway is a by-product of the RNA world.
    Journal of molecular evolution, 2001, Volume: 52, Issue:1

    Topics: Aspartic Acid; Dihydroxyacetone; Dihydroxyacetone Phosphate; Glyceraldehyde; Glyceraldehyde 3-Phosphate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Structure; NAD; Niacin; Quinolinic Acid; RNA

2001
Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:3

    Topics: Adenosine Triphosphate; Aspartic Acid; Citric Acid Cycle; Energy Metabolism; Fatty Acids, Nonesterified; Flavin-Adenine Dinucleotide; Fumarate Hydratase; Gene Deletion; Glucose; Glycerophosphates; Glycolysis; Humans; Lactic Acid; Malates; Mitochondria; Models, Biological; Mutation; NAD; Oxygen Consumption; Palmitic Acid; Phosphofructokinase-1; Pyruvate Dehydrogenase Complex

2001
Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction.
    The Biochemical journal, 2001, May-15, Volume: 356, Issue:Pt 1

    Topics: 17-Hydroxysteroid Dehydrogenases; Aspartic Acid; Blood Proteins; Dehydroepiandrosterone; Dihydrotestosterone; Estrogens; Estrone; Female; Humans; Isoenzymes; Leucine; Membrane Proteins; Models, Chemical; NAD; NADP; Oxidation-Reduction; Placenta; Pregnancy

2001
Characterization of mutants of beta histidine91, beta aspartate213, and beta asparagine222, possible components of the energy transduction pathway of the proton-translocating pyridine nucleotide transhydrogenase of Escherichia coli.
    Archives of biochemistry and biophysics, 2001, Apr-15, Volume: 388, Issue:2

    Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Energy Metabolism; Escherichia coli; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; NADP Transhydrogenases; Oxidation-Reduction; Protein Conformation

2001
Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
    Biochemistry, 2001, May-29, Volume: 40, Issue:21

    Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Enzyme Activation; Escherichia coli; Folic Acid; Glutamic Acid; Glutamine; Kinetics; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Spectrophotometry; Vitamin K

2001
Changes in activities of enzymes related to malate-aspartate shuttle in leukocytes from dogs given a herb supplement.
    The Journal of veterinary medical science, 2001, Volume: 63, Issue:6

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Blood Glucose; Dietary Supplements; Dogs; Drugs, Chinese Herbal; Fatty Acids, Nonesterified; Female; Glutamate Dehydrogenase; Insulin; L-Lactate Dehydrogenase; Leukocytes; Malate Dehydrogenase; Malates; Male; NAD; Triglycerides

2001
NAD+-dependent DNA ligase encoded by a eukaryotic virus.
    The Journal of biological chemistry, 2001, Sep-28, Volume: 276, Issue:39

    Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Base Sequence; Catalysis; Cysteine; DNA Ligases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Evolution, Molecular; Gene Deletion; Genetic Vectors; Models, Biological; Molecular Sequence Data; Mutation; NAD; Phylogeny; Poxviridae; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Tyrosine; Zinc; Zinc Fingers

2001
Activities of enzymes in the malate-aspartate shuttle in the peripheral leukocytes of dogs and cats.
    Veterinary research communications, 2001, Volume: 25, Issue:8

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Blood Glucose; Cats; Cytosol; Dogs; Fatty Acids, Nonesterified; Female; Gene Expression; Glutamate Dehydrogenase; Insulin; L-Lactate Dehydrogenase; Leukocytes; Malate Dehydrogenase; Malates; Male; Mitochondria; NAD; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triglycerides

2001
Conserved residues in domain Ia are required for the reaction of Escherichia coli DNA ligase with NAD+.
    The Journal of biological chemistry, 2002, Mar-22, Volume: 277, Issue:12

    Topics: Alanine; Amino Acid Sequence; Aspartic Acid; DNA Ligases; Dose-Response Relationship, Drug; Escherichia coli; Gene Deletion; Histidine; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Mutation; NAD; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structure-Activity Relationship; Time Factors; Tyrosine

2002
Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.
    The Journal of biological chemistry, 2002, Jun-21, Volume: 277, Issue:25

    Topics: Adenosylhomocysteinase; Animals; Apoenzymes; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Cattle; Circular Dichroism; Crystallography, X-Ray; DNA, Complementary; Escherichia coli; Holoenzymes; Hydrolases; Hydrolysis; Kinetics; Liver; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Protein Binding; Rats; Time Factors; Ultraviolet Rays

2002
Anionic substitutes for catalytic aspartic acids in phosphoribulokinase.
    Archives of biochemistry and biophysics, 2002, Sep-15, Volume: 405, Issue:2

    Topics: Adenosine Triphosphate; Amino Acid Substitution; Anions; Aspartic Acid; Catalytic Domain; Cysteine; Fluorescent Dyes; Kinetics; Models, Molecular; Mutagenesis; NAD; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Recombinant Proteins

2002
Glutamate-115 renders specificity of human 11beta-hydroxysteroid dehydrogenase type 2 for the cofactor NAD+.
    Molecular and cellular endocrinology, 2003, Mar-28, Volume: 201, Issue:1-2

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Computer Simulation; Glutamates; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Phenylalanine; Protein Conformation; Sequence Homology, Amino Acid

2003
Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase.
    The Journal of biological chemistry, 2003, Sep-12, Volume: 278, Issue:37

    Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Aspartic Acid; Coenzymes; Female; Humans; Kinetics; Male; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; NAD; Placenta; Pregnancy; Progesterone Reductase; Protein Conformation; Recombinant Proteins; Steroid Isomerases; Substrate Specificity; Tumor Cells, Cultured

2003
SPECIFICITY OF THE SOLUBLE RNA IN THE CODING OF THE AMINO ACIDS.
    Life sciences (1962), 1963, Volume: 11

    Topics: Amino Acids; Animals; Aspartic Acid; Citric Acid Cycle; Guinea Pigs; Liver; Malate Dehydrogenase; NAD; Proteins; Research; RNA

1963
SYNTHESIS OF GLUTAMATE FROM ALPHA-OXOGLUTARATE AND AMMONIA IN RAT-LIVER MITOCHONDRIA. III. MALATE AS HYDROGEN DONOR.
    Biochimica et biophysica acta, 1963, Oct-01, Volume: 77

    Topics: Adenosine Triphosphate; Ammonia; Amobarbital; Anti-Bacterial Agents; Aspartic Acid; Dinitrophenols; Enzyme Inhibitors; Glutamates; Glutamic Acid; Hydrogen; Ketoglutaric Acids; Liver; Malates; Mitochondria; Mitochondria, Liver; NAD; Oligomycins; Pharmacology; Rats; Research

1963
[NATURE OF THE ENZYME SYSTEMS RESPONSIBLE FOR NITROGEN-SOURCE AMINO ACID UTILIZATION IN BACILLUS SUBTILIS].
    Annales de l'Institut Pasteur, 1964, Volume: 106

    Topics: Alanine; Amidohydrolases; Amino Acid Oxidoreductases; Amino Acids; Aspartic Acid; Bacillus subtilis; Caproates; Glutamates; Isoleucine; Ketoglutaric Acids; Leucine; NAD; Nitrogen; Oxidoreductases; Proteins; Pyruvates; Research; Transaminases; Valerian; Valine

1964
WATER CONTENT OF PAPER AS A VARIABLE IN PAPER CHROMATOGRAPHY.
    Journal of chromatography, 1964, Volume: 14

    Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Aspartic Acid; Autoradiography; Carbon Isotopes; Chromatography; Chromatography, Paper; Escherichia coli; Formates; Fumarates; Glutamates; Glutamine; Guanine Nucleotides; Humidity; Hypoxanthines; Lactates; Malates; NAD; Nucleosides; Nucleotides; Research; Water; Xanthines

1964
THE FLUOROMETRIC DETERMINATION OF ACETYLCHOLINE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Acetates; Acetone; Acetylcholine; Alcohol Oxidoreductases; Amino Acids; Aspartic Acid; Borates; Choline; Coenzyme A; Fluorescence; Fluorometry; Metabolism; NAD; Research; Spectrophotometry

1964
AMINO GROUP FORMATION AND GLUTAMATE SYNTHESIS IN STREPTOCOCCUS BOVIS.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Amino Acids; Asparagine; Aspartic Acid; Carbon; Caseins; Culture Media; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Isocitrate Dehydrogenase; Metabolism; NAD; NADP; Nitrogen; Nucleotides; Research; Streptococcus; Streptococcus bovis

1964
[ROLE OF GLUTAMIC DEHYDROGENASE AND ASPARTIC/GLUTAMIC TRANSAMINASE IN THE OXIDATION OF GLUTAMATE BY SARCOSOMES FROM PIG HEART AND UTERUS].
    Bulletin de la Societe de chimie biologique, 1964, Volume: 46

    Topics: Amino Acids; Animals; Antimetabolites; Arsenicals; Aspartate Aminotransferases; Aspartic Acid; Chromatography; Cytoplasmic Granules; Female; Formates; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Humans; Malonates; Manometry; Metabolism; Mitochondria, Muscle; Muscle, Smooth; Myocardium; NAD; Pharmacology; Research; Swine; Uterus

1964
ALCOHOL HYPOGLYCEMIA. II. A POSTULATED MECHANISM OF ACTION BASED ON EXPERIMENTS WITH RAT LIVER SLICES.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: Alanine; Amino Acids; Aspartic Acid; Autoradiography; Carbohydrate Metabolism; Carbon Dioxide; Carbon Isotopes; Chromatography; Citric Acid Cycle; Ethanol; Fructose; Glucose; Glycerophosphates; Hypoglycemia; Lactates; Liver; Mitochondria; NAD; Oxidoreductases; Pyruvates; Rats; Research; Sorbitol

1965
PHOSPHOENOLPYRUVATE CARBOXYLASE ACTIVITY AND GLYCOGENESIS IN THE FLATWORM, HYMENOLEPIS DIMINUTA.
    Comparative biochemistry and physiology, 1965, Volume: 14

    Topics: Adenosine Triphosphate; Alanine; Alcohol Oxidoreductases; Animals; Aspartic Acid; Carbohydrate Metabolism; Carbon Dioxide; Carboxy-Lyases; Cestoda; Citric Acid Cycle; Dialysis; Fumarates; Glutamates; Glycogen; Glycolysis; Hymenolepis diminuta; Keto Acids; Lactates; Malates; NAD; NADP; Oxaloacetates; Phosphoenolpyruvate Carboxylase; Platyhelminths; Pyruvates; Renal Dialysis; Research; Succinates

1965
Slc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemia.
    Molecular and cellular biology, 2004, Volume: 24, Issue:2

    Topics: Amino Acids; Ammonia; Animals; Argininosuccinate Synthase; Aspartic Acid; Base Sequence; Citrullinemia; Disease Models, Animal; DNA; Female; Gluconeogenesis; Humans; Liver; Male; Membrane Transport Proteins; Mice; Mice, Knockout; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Mutation; NAD; Phenotype; RNA, Messenger; Urea

2004
Involvement of a Glu71-Arg64 couple in the access channel for NADH in cytochrome p450nor.
    Bioscience, biotechnology, and biochemistry, 2004, Volume: 68, Issue:5

    Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Cytochrome P-450 Enzyme System; Fusarium; Glutamic Acid; Heme; Molecular Structure; NAD; Oxidoreductases; Point Mutation

2004
D88A mutant of cytochrome P450nor provides kinetic evidence for direct complex formation with electron donor NADH.
    European journal of biochemistry, 2004, Volume: 271, Issue:14

    Topics: Animals; Aspartic Acid; Bacterial Proteins; Binding Sites; Chlorides; Cytochrome P-450 Enzyme System; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; NAD; Oxidoreductases; Point Mutation; Protein Structure, Tertiary

2004
Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats.
    Neurosurgery, 2005, Volume: 56, Issue:3

    Topics: Animals; Ascorbic Acid; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Energy Metabolism; Head Injuries, Closed; Hypotension; Hypoxia; Male; Malondialdehyde; NAD; NADP; Nucleosides; Oxidative Stress; Phosphates; Purines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2005
A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme.
    Biochemistry, 2005, Mar-08, Volume: 44, Issue:9

    Topics: Animals; Arginine; Ascaris suum; Aspartic Acid; Catalytic Domain; Deuterium Exchange Measurement; Hydrogen-Ion Concentration; Kinetics; Lysine; Malate Dehydrogenase; Models, Chemical; NAD; Phenylalanine; Spectrophotometry; Substrate Specificity; Tyrosine

2005
Aspartate 120 of Escherichia coli methylenetetrahydrofolate reductase: evidence for major roles in folate binding and catalysis and a minor role in flavin reactivity.
    Biochemistry, 2005, May-10, Volume: 44, Issue:18

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alanine; Asparagine; Aspartic Acid; Catalysis; Cold Temperature; Escherichia coli Proteins; Flavin-Adenine Dinucleotide; Folic Acid; Imines; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Potentiometry; Spectrophotometry; Substrate Specificity; Thermodynamics

2005
Possible involvement of glutamic and/or aspartic acid residue(s) and requirement of mitochondrial integrity for the protective effect of creatine against inhibition of cardiac mitochondrial respiration by methylglyoxal.
    Molecular and cellular biochemistry, 2005, Volume: 271, Issue:1-2

    Topics: Alamethicin; Animals; Aspartic Acid; Binding Sites; Cell Respiration; Creatine; Electron Transport Complex I; Glutamic Acid; Goats; Intracellular Membranes; Isoxazoles; Mitochondria, Heart; NAD; NADH Dehydrogenase; Oxygen Consumption; Permeability; Protective Agents; Pyruvaldehyde; Submitochondrial Particles

2005
Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies.
    The Journal of physiology, 2005, Dec-15, Volume: 569, Issue:Pt 3

    Topics: Animals; Aspartic Acid; Computer Simulation; Cytosol; Energy Metabolism; Glycolysis; Humans; Ischemia; Kinetics; Lactic Acid; Malates; Mitochondria; Models, Biological; Myocardial Ischemia; Myocardium; NAD; Oxidation-Reduction; Oxygen Consumption

2005
Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid.
    Plant physiology, 2006, Volume: 141, Issue:3

    Topics: Amino Acid Oxidoreductases; Arabidopsis; Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Multienzyme Complexes; NAD; Pentosyltransferases; Plastids; Quinolinic Acid

2006
Mitochondria from the left heart ventricles of both normotensive and spontaneously hypertensive rats oxidize externally added NADH mostly via a novel malate/oxaloacetate shuttle as reconstructed in vitro.
    International journal of molecular medicine, 2006, Volume: 18, Issue:1

    Topics: Animals; Aspartic Acid; Blood Pressure; Glycerophosphates; Heart Ventricles; Kinetics; Malate Dehydrogenase; Malates; Male; Mitochondria, Heart; Models, Biological; Models, Chemical; NAD; NADP; Oxaloacetic Acid; Oxidation-Reduction; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Statistics as Topic

2006
The importance of redox shuttles to pancreatic beta-cell energy metabolism and function.
    Biochemical Society transactions, 2006, Volume: 34, Issue:Pt 5

    Topics: Animals; Aspartic Acid; Cytosol; Energy Metabolism; Flavin-Adenine Dinucleotide; Glucose; Glycerophosphates; Insulin; Insulin Secretion; Insulin-Secreting Cells; Malates; Mitochondria; Models, Biological; NAD; Oxidation-Reduction

2006
Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle.
    The Journal of biological chemistry, 2007, Mar-09, Volume: 282, Issue:10

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Brain; Calcium; Glutamic Acid; Kinetics; Malates; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Molecular Sequence Data; Muscle, Skeletal; NAD

2007
Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase.
    Biochemistry, 2007, May-08, Volume: 46, Issue:18

    Topics: Adenosine Diphosphate; Asparagine; Aspartic Acid; Catalytic Domain; Humans; Isocitrate Dehydrogenase; Mutagenesis, Site-Directed; NAD; Protein Subunits; Structure-Activity Relationship; Substrate Specificity

2007
Crystal structure of archaeal highly thermostable L-aspartate dehydrogenase/NAD/citrate ternary complex.
    The FEBS journal, 2007, Volume: 274, Issue:16

    Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Archaeal Proteins; Archaeoglobus fulgidus; Aspartic Acid; Binding Sites; Citric Acid; Crystallography, X-Ray; Enzyme Stability; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; NAD; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity; Thermodynamics

2007
NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
    The Journal of biological chemistry, 2007, Nov-23, Volume: 282, Issue:47

    Topics: Amino Acid Motifs; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Catalysis; Crystallography, X-Ray; Diacylglycerol Kinase; Listeria monocytogenes; Magnesium; Mutation, Missense; NAD; Phosphofructokinase-1; Phosphotransferases (Alcohol Group Acceptor); Structure-Activity Relationship; Substrate Specificity

2007
The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast.
    Genes & development, 2008, Apr-01, Volume: 22, Issue:7

    Topics: Aspartate Aminotransferases; Aspartic Acid; Biological Transport; Blotting, Western; Cell Nucleus; Cytoplasm; Electron Transport; Energy Metabolism; Fungal Proteins; Glycerolphosphate Dehydrogenase; Malate Dehydrogenase; Malates; Mitochondria; Mutation; NAD; Saccharomyces cerevisiae; Signal Transduction; Time Factors; Yeasts

2008
Conserved water mediated H-bonding dynamics of inhibitor, cofactor, Asp 364 and Asn 303 in human IMPDH II.
    Journal of biomolecular structure & dynamics, 2009, Volume: 26, Issue:4

    Topics: Asparagine; Aspartic Acid; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Enzyme Stability; Humans; Hydrogen Bonding; IMP Dehydrogenase; Inosine Monophosphate; Ligands; NAD; Thermodynamics; Water

2009
Calcium signaling in brain mitochondria: interplay of malate aspartate NADH shuttle and calcium uniporter/mitochondrial dehydrogenase pathways.
    The Journal of biological chemistry, 2009, Mar-13, Volume: 284, Issue:11

    Topics: Animals; Aspartic Acid; Brain; Calcium; Calcium Channels; Calcium Signaling; Cytosol; Ketoglutaric Acids; Malates; Mice; Mitochondria, Heart; Mitochondrial Proteins; NAD; Organic Anion Transporters

2009
Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons.
    Journal of neurochemistry, 2009, Volume: 110, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Aspartic Acid; Brain Chemistry; Cells, Cultured; Cerebellum; Cytosol; Energy Metabolism; Glucose; Glutamic Acid; Ketone Bodies; Malate Dehydrogenase; Mice; NAD; Neurons; Neurotransmitter Agents; Subcellular Fractions; Synaptic Transmission

2009
The unique kinetic behavior of the very large NAD-dependent glutamate dehydrogenase from Janthinobacterium lividum.
    Bioscience, biotechnology, and biochemistry, 2010, Volume: 74, Issue:4

    Topics: Aspartic Acid; Catalysis; Chromobacterium; Glutamate Dehydrogenase; Glutamic Acid; Ketoglutaric Acids; Kinetics; NAD; Oxalobacteraceae

2010
Synthesizing and salvaging NAD: lessons learned from Chlamydomonas reinhardtii.
    PLoS genetics, 2010, Sep-09, Volume: 6, Issue:9

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Biological Evolution; Biosynthetic Pathways; Chlamydomonas reinhardtii; Gene Expression Regulation; Gene Expression Regulation, Plant; Genes, Plant; Mammals; Molecular Sequence Data; Mutagenesis, Insertional; Mutation; NAD; Niacinamide; Nicotinamide-Nucleotide Adenylyltransferase; Phenotype; Plant Proteins; Pyridines; Time Factors; Transcription, Genetic

2010
Visible wavelength spectrophotometric assays of L-aspartate and D-aspartate using hyperthermophilic enzyme systems.
    Analytical biochemistry, 2011, Feb-01, Volume: 409, Issue:1

    Topics: Acetic Acid; Amino Acid Isomerases; Amino Acid Oxidoreductases; Animals; Aspartic Acid; D-Aspartic Acid; Escherichia coli Proteins; Isomerism; Liver; Methylphenazonium Methosulfate; Mice; NAD; Oxidation-Reduction; Spectrophotometry; Swine

2011
A novel L-aspartate dehydrogenase from the mesophilic bacterium Pseudomonas aeruginosa PAO1: molecular characterization and application for L-aspartate production.
    Applied microbiology and biotechnology, 2011, Volume: 90, Issue:6

    Topics: Amino Acid Oxidoreductases; Aspartic Acid; Cloning, Molecular; Coenzymes; Enzyme Stability; Escherichia coli; Kinetics; Molecular Weight; NAD; NADP; Oxaloacetic Acid; Protein Multimerization; Pseudomonas aeruginosa; Recombinant Proteins; Substrate Specificity; Temperature

2011
Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate.
    Brain research, 2011, Aug-02, Volume: 1404

    Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Aspartic Acid; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Brain Injuries; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Energy Metabolism; Glutathione; Male; Models, Biological; NAD; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sodium Lactate

2011
A non-NadB type L-aspartate dehydrogenase from Ralstonia eutropha strain JMP134: molecular characterization and physiological functions.
    Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:8

    Topics: Amino Acid Oxidoreductases; Aspartate Aminotransferases; Aspartic Acid; Bacterial Proteins; Cloning, Molecular; Cupriavidus necator; Dimerization; Escherichia coli; Gene Deletion; Gene Expression; Hydroxybutyrates; Kinetics; Mass Spectrometry; NAD; NADP; Polyesters; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Transformation, Bacterial

2011
Malate-aspartate shuttle and exogenous NADH/cytochrome c electron transport pathway as two independent cytosolic reducing equivalent transfer systems.
    Archives of biochemistry and biophysics, 2012, Feb-15, Volume: 518, Issue:2

    Topics: Animals; Apoptosis; Aspartic Acid; Biological Transport, Active; Cytochromes c; Electron Transport; Glutamate Dehydrogenase; Ketoglutaric Acids; Malates; Mitochondria, Liver; Mitochondrial Proteins; NAD; Oxidation-Reduction; Rats

2012
Aralar mRNA and protein levels in neurons and astrocytes freshly isolated from young and adult mouse brain and in maturing cultured astrocytes.
    Neurochemistry international, 2012, Volume: 61, Issue:8

    Topics: Aging; Animals; Aspartic Acid; Astrocytes; Brain; Cell Separation; Cells, Cultured; Cellular Senescence; Cytoplasm; Energy Metabolism; Female; Glutamic Acid; Lactic Acid; Male; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; NAD; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Primary Cell Culture; Pyruvic Acid; Real-Time Polymerase Chain Reaction; RNA, Messenger

2012
Exploring the molecular basis for selective binding of homoserine dehydrogenase from Mycobacterium leprae TN toward inhibitors: a virtual screening study.
    International journal of molecular sciences, 2014, Jan-24, Volume: 15, Issue:2

    Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Enzyme Inhibitors; Homoserine Dehydrogenase; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Sequence Data; Mycobacterium leprae; NAD; Protein Conformation; Reproducibility of Results; ROC Curve; Sequence Alignment; Substrate Specificity

2014
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
    Nature, 2014, Nov-20, Volume: 515, Issue:7527

    Topics: Adenosine Monophosphate; Animals; Aspartic Acid; Citric Acid Cycle; Disease Models, Animal; Electron Transport; Electron Transport Complex I; Fumarates; Ischemia; Malates; Male; Metabolomics; Mice; Mitochondria; Myocardial Infarction; Myocardium; Myocytes, Cardiac; NAD; Reactive Oxygen Species; Reperfusion Injury; Stroke; Succinate Dehydrogenase; Succinic Acid

2014
Impaired cytosolic NADH shuttling and elevated UCP3 contribute to inefficient citric acid cycle flux support of postischemic cardiac work in diabetic hearts.
    Journal of molecular and cellular cardiology, 2015, Volume: 79

    Topics: Animals; Aspartic Acid; Carbon-13 Magnetic Resonance Spectroscopy; Carrier Proteins; Citric Acid Cycle; Cytosol; Diabetes Mellitus, Experimental; Hemodynamics; Ion Channels; Malates; Male; Mice, Inbred C57BL; Mitochondrial Proteins; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NAD; Oxidation-Reduction; Perfusion; PPAR alpha; Uncoupling Protein 2; Uncoupling Protein 3

2015
SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth.
    The EMBO journal, 2015, Apr-15, Volume: 34, Issue:8

    Topics: Acetylation; Animals; Aspartate Aminotransferase, Mitochondrial; Aspartic Acid; Biological Transport; Carcinoma, Pancreatic Ductal; Cell Proliferation; Cells, Cultured; HEK293 Cells; Humans; Malates; Male; Mice; Mice, Inbred C57BL; Mice, Nude; NAD; Oxidation-Reduction; Pancreatic Neoplasms; Protein Processing, Post-Translational; Sirtuin 3

2015
Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain.
    Neurobiology of aging, 2015, Volume: 36, Issue:11

    Topics: Acetylcholine; Aging; Animals; Antioxidants; Aspartic Acid; Brain; Carnitine; DNA Damage; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Female; Glutamates; Male; Metabolomics; Mice; Mutation; NAD; Neurotransmitter Agents; Physical Conditioning, Animal; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases

2015
Respiration and substrate transport rates as well as reactive oxygen species production distinguish mitochondria from brain and liver.
    BMC biochemistry, 2015, Sep-10, Volume: 16

    Topics: Animals; Aspartic Acid; Biological Transport; Brain; Cell Respiration; Dicarboxylic Acid Transporters; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Gene Expression Regulation; Glutamic Acid; Kinetics; Liver; Malates; Membrane Potential, Mitochondrial; Mice; Mitochondria, Liver; NAD; Organ Specificity; Reactive Oxygen Species; Succinic Acid

2015
Dual activity of quinolinate synthase: triose phosphate isomerase and dehydration activities play together to form quinolinate.
    Biochemistry, 2015, Oct-27, Volume: 54, Issue:42

    Topics: Aspartic Acid; Bacterial Proteins; Dihydroxyacetone Phosphate; Metabolic Networks and Pathways; Models, Chemical; Multienzyme Complexes; NAD; Quinolinic Acid; Thermotoga maritima; Triose-Phosphate Isomerase

2015
Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion.
    Oncotarget, 2016, Aug-02, Volume: 7, Issue:31

    Topics: Action Potentials; Adenosine Triphosphate; Aldehyde Dehydrogenase; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytosol; Female; Gossypol; Humans; Lung Neoplasms; Malates; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; NAD; NADP; Neoplasm Transplantation; Oxidative Phosphorylation; Oxidoreductases Acting on CH-NH Group Donors; Phenformin; RNA, Small Interfering

2016
Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.
    Cell metabolism, 2016, 11-08, Volume: 24, Issue:5

    Topics: Animals; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Electron Transport Complex I; Homeostasis; Humans; Metformin; Mice, Nude; Mitochondria; NAD; Neoplasms; Pyruvic Acid; Tumor Microenvironment

2016
Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC.
    Cell death & disease, 2016, 12-08, Volume: 7, Issue:12

    Topics: A549 Cells; Adenosine Triphosphate; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Death; Cell Proliferation; Cell Survival; Cytosol; Drug Synergism; Fluorouracil; Gene Knockdown Techniques; Glutamic Acid; Glutaminase; Glutamine; Lung Neoplasms; Malates; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; NAD; Oxidation-Reduction; Sulfides; Thiadiazoles; Thymidylate Synthase; Xenograft Model Antitumor Assays

2016
Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD
    Cell death & disease, 2018, 11-14, Volume: 9, Issue:11

    Topics: Adenosine Triphosphate; Aspartic Acid; Cell Death; Culture Media; Electron Transport Complex I; Fibroblasts; Galactose; Gene Expression; Glycolysis; Humans; Ketoglutaric Acids; Leigh Disease; Malates; Mitochondria; Mitochondrial Diseases; Mutation; NAD; NADH Dehydrogenase; Oxaloacetic Acid; Primary Cell Culture; Pyruvic Acid; Skin

2018
Low metformin causes a more oxidized mitochondrial NADH/NAD redox state in hepatocytes and inhibits gluconeogenesis by a redox-independent mechanism.
    The Journal of biological chemistry, 2019, 02-22, Volume: 294, Issue:8

    Topics: Animals; Aspartic Acid; Cells, Cultured; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glycolysis; Hepatocytes; Hypoglycemic Agents; Lactic Acid; Malates; Male; Metformin; Mice; Mice, Inbred C57BL; Mitochondria, Liver; NAD; Oxidation-Reduction; Phosphofructokinase-1; Rats; Rats, Wistar

2019
Malate-aspartate shuttle promotes l-lactate oxidation in mitochondria.
    Journal of cellular physiology, 2020, Volume: 235, Issue:3

    Topics: Aspartic Acid; Colonic Neoplasms; HCT116 Cells; Homeostasis; Humans; Lactic Acid; Malates; Mitochondria; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Warburg Effect, Oncologic

2020
MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells.
    Blood, 2020, 07-30, Volume: 136, Issue:5

    Topics: Animals; Aspartic Acid; Fetus; Hematopoietic Stem Cells; Liver; Malates; Metabolomics; Mice; Mice, Transgenic; NAD; Optical Imaging

2020
Optimal pH shift of the NADH oxidase from Lactobacillus rhamnosus with a single mutation.
    Biotechnology letters, 2021, Volume: 43, Issue:7

    Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Lacticaseibacillus rhamnosus; Models, Molecular; Molecular Docking Simulation; Multienzyme Complexes; Mutagenesis, Site-Directed; NAD; NADH, NADPH Oxidoreductases; Protein Conformation; Protein Engineering; Substrate Specificity

2021
Alteration of cofactor specificity of the acrylyl-CoA reductase from Escherichia coli.
    Biotechnology letters, 2021, Volume: 43, Issue:7

    Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Mutagenesis, Site-Directed; NAD; NADP; Protein Engineering; Quinone Reductases; Serine; Substrate Specificity

2021
Expression, purification, and biochemical characterization of an NAD
    Protein expression and purification, 2021, Volume: 188

    Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Burkholderiaceae; Chromatography, Gel; Cloning, Molecular; Escherichia coli; Euplotes; Gene Expression; Genetic Vectors; Homoserine; Homoserine Dehydrogenase; Kinetics; Molecular Weight; NAD; NADP; Protein Multimerization; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Small Ubiquitin-Related Modifier Proteins; Symbiosis

2021
Biguanide drugs enhance cytotoxic effects of cisplatin by depleting aspartate and NAD+ in sensitive cancer cells.
    Cancer biology & therapy, 2021, 12-02, Volume: 22, Issue:10-12

    Topics: Antineoplastic Agents; Aspartic Acid; Cisplatin; Metformin; NAD; Neoplasms; Pharmaceutical Preparations

2021
Arabidopsis nitrate-induced aspartate oxidase gene expression is necessary to maintain metabolic balance under nitrogen nutrient fluctuation.
    Communications biology, 2022, 05-09, Volume: 5, Issue:1

    Topics: Arabidopsis; Aspartic Acid; Gene Expression; Gene Expression Regulation, Plant; NAD; Nitrates; Nitrogen; Nutrients

2022
Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells.
    Molecular cell, 2022, 09-01, Volume: 82, Issue:17

    Topics: Aspartic Acid; Glucose; Glycolysis; Lactic Acid; Malates; NAD

2022
Hypoxia-responsive nanocarriers for chemotherapy sensitization via dual-mode inhibition of hypoxia-inducible factor-1 alpha.
    Journal of colloid and interface science, 2022, Dec-15, Volume: 628, Issue:Pt B

    Topics: Antineoplastic Agents; Aspartic Acid; Caspase 3; Cell Hypoxia; Cell Line, Tumor; Cytochromes c; Dicumarol; Female; Glutathione; Humans; Hypoxia; Micelles; NAD; NADP; Nitroimidazoles; Oxygen; Phosphates; Polyethylene Glycols; Polymers; Quinones; Sorafenib; Thioredoxins

2022
Reversible Glutamate Coordination to High-Valent Nickel Protects the Active Site of a [NiFe] Hydrogenase from Oxygen.
    Journal of the American Chemical Society, 2022, 09-21, Volume: 144, Issue:37

    Topics: Alanine; Aspartic Acid; Catalytic Domain; Glutamic Acid; Glutamine; Hydrogenase; Hydrogenophilaceae; Iron; Ligands; NAD; Nickel; Oxidation-Reduction; Oxygen

2022
Nicotinamide riboside rescues dysregulated glycolysis and fatty acid β-oxidation in a human hepatic cell model of citrin deficiency.
    Human molecular genetics, 2023, 05-18, Volume: 32, Issue:11

    Topics: Aspartic Acid; Citrullinemia; Fatty Acids; Glycolysis; Hepatocytes; Humans; Hyperammonemia; Malates; Mitochondrial Membrane Transport Proteins; NAD; Urea

2023
Mitochondrial redox adaptations enable alternative aspartate synthesis in SDH-deficient cells.
    eLife, 2023, 03-08, Volume: 12

    Topics: Aspartic Acid; Citric Acid Cycle; Humans; NAD; Oxidation-Reduction; Succinate Dehydrogenase

2023
The mitochondrial NADH shuttle system is a targetable vulnerability for Group 3 medulloblastoma in a hypoxic microenvironment.
    Cell death & disease, 2023, Nov-30, Volume: 14, Issue:11

    Topics: Aspartic Acid; Cerebellar Neoplasms; Child; Humans; Hypoxia; Malates; Medulloblastoma; NAD; Oxygen; Tumor Microenvironment

2023