nad has been researched along with adenosine diphosphate ribose in 650 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 184 (28.31) | 18.7374 |
| 1990's | 267 (41.08) | 18.2507 |
| 2000's | 113 (17.38) | 29.6817 |
| 2010's | 66 (10.15) | 24.3611 |
| 2020's | 20 (3.08) | 2.80 |
| Authors | Studies |
|---|---|
| Martin, RB; Sovago, I | 1 |
| Moss, J; Oppenheimer, NJ; Stanley, SJ | 1 |
| Lin, MC; Moss, J; Stanley, SJ | 1 |
| Caplan, AI; Mandel, P; Niedergang, C; Okazaki, H | 1 |
| Adamietz, P; Bredehorst, R; Hilz, H; Wielckens, K | 2 |
| Bredehorst, R; Goebel, M; Hilz, H; Kittler, M; Klapproth, K; Renzi, F | 1 |
| Boyd, RS; Donnelly, LE; MacDermot, J | 1 |
| Billiar, TR; Brüne, B; Di Silvio, M; Lapetina, EG; McDonald, B; Molina y Vedia, L; Reep, B | 1 |
| Beckmann, R; Buchner, K; Hilbert, R; Hucho, F; Otto, H | 1 |
| Grenfell, S; Kennard, N; Ray, K; Rollins, P; Smithers, N; Solari, R; Thompson, N; Witham, S | 1 |
| Moss, J; Serventi, IM; Vaughan, M | 1 |
| Carmena, MJ; Clemente, C; Guijarro, LG; Prieto, JC | 1 |
| Ho, YK; Lee, RH; Lieberman, BS; Lolley, RN; Ting, TD; Tobias, DE | 1 |
| Purich, DL; Raffaelli, N; Scaife, RM | 1 |
| Blais, A; Couvineau, A; Darmoul, D; Daviaud, D; Laburthe, M; Paris, H; Rouot, B; Rouyer-Fessard, C; Voisin, T | 1 |
| Neal, AR; Robertson, RP; Seaquist, ER; Shoger, KD; Walseth, TF | 1 |
| Coghill, JE; Kittler, JM; Strittmatter, P | 1 |
| Snyder, SH; Zhang, J | 2 |
| Benatti, U; De Flora, A; Franco, L; Guida, L; Zocchi, E | 1 |
| Aranda, A; Sánchez-Pacheco, A | 1 |
| Baker, PJ; Britton, KL; Rice, DW; Rob, A; Stillman, TJ | 1 |
| Angus, CW; Avigan, J; Moss, J; Murtagh, JJ; Stevens, LA; Vaughan, M | 1 |
| Brüne, B; Dimmeler, S; Lottspeich, F | 1 |
| Cacciamani, T; Corda, D; D'Arcangelo, D; Di Girolamo, M; Gierschik, P | 1 |
| Haun, RS; Moss, J; Price, SR; Stanley, SJ; Vaughan, M; Welsh, CF | 1 |
| Hardy, DL; Mowbray, J | 2 |
| Brüne, B; Dimmeler, S; Lapetina, EG | 1 |
| Heidenreich, KA; Moises, RS | 1 |
| Akinshola, BE; Mezey, E; Potter, JJ; Sharma, S | 1 |
| Boyer, CS; Gogvadze, V; Kass, GE; Kim, Y; Orrenius, S; Zhukova, A | 1 |
| Collier, RJ; Wilson, BA | 1 |
| Chiba, K; Hoshi, M; Katada, T; Tadenuma, H; Takahashi, K | 1 |
| Aktories, K; Just, I; Koch, G; Mohr, C | 1 |
| Rannels, DE; Russo, LA; Rybin, VO; Uhal, BD | 1 |
| Disher, RM; Ramdas, L; Wensel, TG | 1 |
| Chin, GJ; Reese, TS; Schwartz, JH; Vogel, SS | 1 |
| Barbieri, JT; Cortina, G; Krueger, KM | 1 |
| Alvarez-Gonzalez, R; Martinez, M; Moss, J; Price, SR | 1 |
| Fleischer, B; Gerardy-Schahn, R; Mittrücker, HW; Schultze, U | 1 |
| Aarhus, R; Lee, HC | 2 |
| Law, PY; Loh, HH; Roerig, SC | 1 |
| Kass, GE; Meier, P; Richter, C; Schlegel, J | 1 |
| Koshiyama, H; Lee, HC; Tashjian, AH | 1 |
| Ishibashi, S; Kurokawa, T; Sato, E; Yamashita, A; Yasuda, H | 1 |
| Kahn, RA | 1 |
| Kopf, GS; Woolkalis, MJ | 1 |
| Casey, PJ; Gilman, AG; Pang, IH | 1 |
| Böhm, M; Camps, M; Erdmann, E; Gierschik, P; Jakobs, K; Larisch, K | 1 |
| Cohen-Armon, M; Sokolovsky, M | 1 |
| Imaizumi, T; Watanabe, Y; Yoshida, H | 1 |
| Hamm, HE; Kaufman, LS; Rasenick, MM; Warpeha, KM | 1 |
| Gierschik, P; Jakobs, KH; Müller, U; Reithmann, C; Werdan, K | 1 |
| Ludden, PW; Lueddecke, BA; Woehle, DL | 1 |
| Collier, RJ; Reich, KA; Weinstein, BR; Wilson, BA | 1 |
| Florin, I; Thelestam, M | 2 |
| Enger, SM; James, SJ; Makinodan, T | 1 |
| Loesberg, C; Smets, LA; van Rooij, H | 1 |
| Brann, MR; Jones, TL; Merendino, JJ; Simonds, WF; Spiegel, AM | 1 |
| Haraguchi, K; Rodbell, M | 1 |
| Burdett, E; Klip, A; Mills, GB | 1 |
| Tsuda, M; Tsuda, T | 1 |
| Jones, J; Schultz, RM | 1 |
| Dhanasekaran, N; Johnson, GL; Ruoho, AE; Vaillancourt, RR | 1 |
| Carr, C; Knowler, J; Loney, C; Milligan, G; Unson, C | 1 |
| Alsharif, M; Apweiler, R; Branford White, CJ; Brunt, RV; Whish, WJ | 1 |
| Berti-Mattera, L; Chang, CH; Douglas, J; Hopfer, U; Sims, C; Zhou, J | 1 |
| Barnett, JV; Galper, JB; Griendling, KK; Lassegue, B; Shamah, SM | 1 |
| Althaus, FR; Kleczkowska, HE; Szumiel, I | 1 |
| Englard, S; Seifter, S | 1 |
| Meier, P; Richter, C | 1 |
| Aktories, K; Geipel, U; Just, I; Wegner, A | 1 |
| Corrèze, C; Delemer, B; Dib, K; Jacquemin, C; Saunier, B | 1 |
| Bankhurst, AD; Whalen, MM | 1 |
| Nilsson, L; Nygård, O | 2 |
| Akino, T; Fukada, Y; Ohguro, H; Saito, T; Yoshizawa, T | 1 |
| Lavergne, JP; Marzouki, A; Reboud, AM; Reboud, JP | 1 |
| Brüne, B; Lapetina, EG; Molina y Vedia, L | 1 |
| Conner, DA; Mansour, TE | 1 |
| Hoffman, BB; Thomas, JM | 1 |
| Audigier, Y; Bockaert, J; Journot, L | 1 |
| Iyengar, R; Premont, RT | 1 |
| Costa, T; Lang, J | 1 |
| Gierschik, P; Jakobs, KH; Sidiropoulos, D | 1 |
| Carson, DA; Wasson, DB; Yamanaka, H | 1 |
| Milligan, G | 2 |
| Ribeiro-Neto, FA; Rodbell, M | 1 |
| Hilz, H; Janssen, OE | 1 |
| Milligan, G; Mullaney, I | 1 |
| Cameselle, JC; Costas, MJ; García-Díaz, M; Hernández, MT; Miró, A | 1 |
| Benjamin, RC; Jacobson, EL; Jacobson, MK; Moss, J; Rankin, PW | 1 |
| Ghani, QP; Hunt, TK; Hussain, MZ | 1 |
| Costa, T; Klinz, FJ | 1 |
| Millner, PA; Robinson, PS | 1 |
| Gawler, DJ; Houslay, MD; Milligan, G; Wilson, A | 1 |
| Clark, BF; Rattan, SI; Riis, B | 1 |
| Burnette, WN; Kaslow, HR; Mar, VL; Schlotterbeck, JD | 1 |
| Lee, HC; Rusinko, N | 1 |
| Boĭko, LM; Sen'ko, LN; Velikiĭ, NN | 1 |
| Cornett, LE; Norris, JS | 1 |
| Borenstein, R; Endrenyi, L; Schimmer, BP; Tsao, J | 1 |
| Aranda, A; Copp, R; Pascual, A; Samuels, H | 1 |
| Frei, B; Richter, C | 1 |
| Coburn, J; Gill, DM | 1 |
| Gill, DM; Tamir, A | 1 |
| McCloskey, MA | 1 |
| Abramson, SN; Barrett, DA; Harden, TK; Hughes, AR; Martin, MW; Molinoff, PB; Neve, KA | 1 |
| Downs, RW; Gierschik, P; Levine, MA; Spiegel, AM | 1 |
| Brasier, RS; Gantzos, RD; Neubig, RR | 1 |
| Howlett, AC; Khachatrian, LL; Qualy, JM | 1 |
| Bilezikian, JP; Chow, YK; Robinson, RB; Steinberg, SF | 1 |
| Bratt, GT; Clapper, DL; Hayes, RN; Lee, HC; Walseth, TF | 1 |
| Gorski, J; Guo, JZ | 1 |
| Bauer, PI; Hakam, A; Kun, E | 1 |
| Baughman, KL; Feldman, AM; Levine, MA; Van Dop, C | 1 |
| Hara, N; Mishima, K; Shimoyama, M; Tanigawa, Y; Tsuchiya, M | 1 |
| Agarwal, S; Drysdale, BE; Shin, HS | 1 |
| Kitamura, Y; Nomura, Y; Segawa, T | 1 |
| Arlett, CF; James, MR; Lehmann, AR; Poirier, V | 1 |
| Asano, T; Ogasawara, N; Ui, M | 1 |
| Balestrieri, C; Giovane, A; Quagliuolo, L; Servillo, L | 2 |
| Sauermann, G; Wesierska-Gadek, J | 1 |
| Gaal, JC; Pearson, CK | 1 |
| Rodan, GA; Rodan, SB | 1 |
| Faraone Mennella, MR; Farina, B; Leone, E | 1 |
| Gaal, JC; Pearson, CK; Prise, KM | 1 |
| Honma, T; Mandel, P | 1 |
| Casini, A; Del Principe, D; Di Giulio, S; Finazzi-Agrò, A; Mancuso, G; Menichelli, A | 1 |
| Adolph, KW | 3 |
| Acheson, SA; Kirkman, HN; Wolfenden, R | 1 |
| Lowery, RG; Ludden, PW; Saari, LL | 1 |
| Blackmore, PF; Exton, JH; Lynch, CJ; Morbach, L | 1 |
| Graves, J; Hildebrandt, JD; Stolzenberg, E | 1 |
| Buki, K; Hakam, A; Kun, E; McLick, J | 1 |
| Chang, PP; Holmes, RK; Moss, J; Twiddy, EM | 1 |
| Taniguchi, T | 1 |
| Endo, H; Kawashima, K; Tanuma, S | 1 |
| Furuyama, S; Hara-Yokoyama, M | 1 |
| Fujiwara, M; Imura, H; Morii, N; Nakao, K; Narumiya, S; Ohashi, Y; Sekine, A | 1 |
| Althaus, FR; Alvarez-Gonzalez, R; Moss, J; Niedergang, C | 1 |
| Aktories, K; Just, I; Rosenthal, W | 1 |
| Lowery, RG; Ludden, PW | 1 |
| Barkey, RJ; Calvo, JC; Dufau, ML | 1 |
| Hingorani, VN; Ho, YK | 1 |
| Lapetina, EG; Molina y Vedia, L; Nolan, RD | 1 |
| Chapman, BE; Kuchel, PW | 1 |
| Caplan, AI; Cherney, BW; Midura, RJ | 1 |
| Kolkhidashvili, KM; Margiani, DO; Michilashvili, RD; Zaalishvili, TM | 1 |
| Aboul-Ela, N; Jacobson, EL; Jacobson, MK | 1 |
| Fanick, W; Hilz, H; Koch, R; Meyer, T | 1 |
| Hewlett, EL; Luttrell, LM; Rogol, AD; Romero, G | 1 |
| Austen, B; Robinson, A | 1 |
| Elliott, GC; Johnson, RT; Squires, S | 1 |
| Felgner, P; Gibbons, I; Tarnowski, T; Ullman, EF | 1 |
| Dell'Orco, RT; Duncan, MR; Jacobson, MK; King, RL; Rankin, PR | 1 |
| Avioli, RC; Bell, NH; Bilezikian, JP; Greene, VS; Owens, JM; Shane, E; Yeh, M | 1 |
| Ohishi, I; Tsuyama, S | 1 |
| Aktories, K; Boschek, CB; Presek, P; Reuner, KH | 1 |
| Kvassman, J; Pettersson, G | 1 |
| Callender, R; Chen, D; Martin, C; Rhee, KW; Sloan, D; Yue, KT | 1 |
| He, C | 1 |
| Roitelman, J; Shechter, I | 1 |
| Asadchikov, VE; Berezin, IV; Egorov, AM; Lamzin, VS; Popov, VO | 1 |
| Narumiya, S; Ohashi, Y | 1 |
| Adolph, KW; Song, MK | 3 |
| Abramowitz, J; Campbell, AR | 1 |
| Malbon, CC; Mangano, TJ; Watkins, DC | 1 |
| Chang, AW; Mekalanos, JJ; Moss, J; Watkins, PA; Yost, DA | 1 |
| Decker, K; Hakam, A; Jackowski, G; Kirsten, E; Kun, E; McLick, J | 1 |
| Akita, Y; Saito, T; Sakuma, S; Yajima, Y | 1 |
| Donovan, JJ; Montal, M; Simon, MI | 1 |
| Dreyfus, JC; Kahn, A; Skala, H; Vibert, M; Weber, A | 1 |
| Davydova, EK; Ovchinnikov, LP; Sitikov, AS | 1 |
| Smulson, ME; Sugimura, T | 1 |
| Eklund, H; Jones, TA; Samama, JP | 1 |
| Abood, ME; Bourne, HR; Hurley, JB; Pappone, MC; Stryer, L | 1 |
| Amamoo, DG; Bernofsky, C | 1 |
| Gill, DM; Lefkowitz, RJ; Limbird, LE | 1 |
| Garbrecht, M; Hilz, H; Kittler, M; Wielckens, K | 1 |
| Moss, J; Vaughan, M; Watkins, PA | 2 |
| Anderson, BM; Pekala, PH; Yost, DA | 1 |
| Bodwin, JS; Cho-Chung, YS; Clair, T; Hill, DM | 1 |
| Baulieu, EE; Boquet, P; Godeau, F; Schorderet, M; Schorderet-Slatkine, S | 1 |
| Gottschalk, ME; Kemp, RG | 1 |
| Filetti, S; Rapoport, B | 1 |
| al-Jumaliy, W; Coffman, DS; Haley, BE; Leichtling, BH; Rickenberg, HV; Yaeger, ES | 1 |
| Noscov, AN; Sysueva, EG | 1 |
| Bredehorst, R; Gartemann, A; Hilz, H; Strätling, WH; Wielckens, K | 1 |
| Cayley, PJ; Kerr, IM | 1 |
| Koide, SS; Momii, A | 1 |
| Hilz, H; Lindner, C | 1 |
| Hayaishi, O; Inada, S; Kawaichi, M; Ogata, N; Ueda, K | 1 |
| Burns, DL; Chang, PP; Cutilletta, AF; Moss, J; Vaughan, M | 1 |
| Bokoch, GM; Gilman, AG; Hewlett, EL; Katada, T; Northup, JK | 1 |
| Siebert, G; Stärk, D | 1 |
| Szumiel, I | 1 |
| Burns, DL; Hewlett, EL; Hsia, JA; Moss, J; Myers, GA; Stanley, SJ; Yost, DA | 1 |
| Johnstone, AP; Williams, GT | 1 |
| Elks, ML; Hewlett, E; Manganiello, VC; Moss, J; Vaughan, M; Watkins, PA | 1 |
| Jacobson, EL; Jacobson, MK; Mingmuang, M; Payne, DM; Smith, JY | 1 |
| Cummings, AM; Yochim, JM | 1 |
| Itaya, A; Kamiya, T; Koide, SS; Tanaka, Y; Yoshihara, K | 1 |
| Brown, JE; Kaupp, UB; Malbon, CC | 1 |
| Garciá-Sáinz, JA; Malbon, CC; Rapiejko, PJ | 1 |
| Bodley, JW; Dunlop, PC; VanNess, BG | 1 |
| Holtlund, J; Kristensen, T; Laland, SG; Ostvold, AC | 1 |
| Alouf, JE; Berthillier, G; Megret, F; Monneron, A | 1 |
| Bredehorst, R; Hilz, H; Lengyel, H; Siebert, G; Stärk, D | 1 |
| Doberska, CA; MacPherson, AJ; Martin, BR | 1 |
| Nassau, PM; Tait, RM | 1 |
| Baumhüter, S; Lötscher, HR; Moser, B; Richter, C; Winterhalter, KH | 1 |
| Fraser, BA; Gilman, AG; Kahn, RA; Manning, DR | 1 |
| Adamietz, P; Fanick, W; Hilz, H; Klapproth, K; Koch, R | 1 |
| Greer, WL; Kaplan, JG | 1 |
| Crabbe, MJ; Ting, HH | 1 |
| Katada, T; Tamura, M; Ui, M | 1 |
| Hayaishi, O; Komura, H; Nakanishi, K; Oka, J; Ueda, K | 1 |
| Amir-Zaltsman, Y; Ezra, E; Littauer, UZ; Salomon, Y; Scherson, T; Zutra, A | 1 |
| Bormann, EJ; Gräfe, U; Truckenbrodt, G | 1 |
| Poirier, GG; Savard, P | 1 |
| Kun, E; Romaschin, AD | 1 |
| Bredehorst, R; George, E; Hilz, H; Schmidt, A; Wielckens, K | 1 |
| Berthillier, G; d'Alayer, J; Monneron, A | 1 |
| Corpus, VM; Hammerman, MR; Morrissey, JJ | 1 |
| Fine, LG; Lang, RP; Lee, SH; Nord, EP; Sakhrani, L; Yanagawa, N | 1 |
| Henis, YI; Levitzki, A | 2 |
| Katada, T; Ui, M | 1 |
| Fukushima, M; Hayaishi, O; Ikai, K; Nakamura, T; Ueda, K | 1 |
| Adler, A; Horn, RS; Lystad, E; Walaas, O | 1 |
| Brand, L; Ross, JB; Ross, PD; Subramanian, S | 1 |
| Andersson, P; Kvassman, J; Oldén, B; Pettersson, G | 1 |
| Anderson, WB; Pinkett, MO | 1 |
| Malbon, CC | 1 |
| Lester, HA; Michaelson, DM; Steer, ML | 1 |
| Hammerman, MR; Hansen, VA; Morrissey, JJ | 1 |
| Browning, ET; Hawkins, DJ | 1 |
| Biellmann, JF; Branlant, G; Eiler, B | 1 |
| Bredehorst, R; Hilz, H; Schlüter, MM | 1 |
| Beckner, SK; Blecher, M | 1 |
| Izawa, M; Kawashima, K | 1 |
| Kun, E | 1 |
| Bredehorst, R; Gerisch, G; Hilz, H; Klapproth, K; Scheidegger, C | 1 |
| Cuatrecasas, P; Hebdon, GM; Le Vine, H; Sahyoun, NE; Schmitges, CJ | 1 |
| Moss, J; Stanley, SJ; Vaughan, M; Watkins, PA | 1 |
| Benjamin, RC; Gill, DM | 1 |
| Carroll, SF; Collier, RJ; Lory, S | 1 |
| Aboul-Ela, N; Jacobson, MK; Slama, JT | 1 |
| Aktories, K; Just, I | 1 |
| Morii, N; Narumiya, S | 1 |
| Chono, E; Fujimura, Y; Ishibashi, S; Kurokawa, T; Takahashi, K | 1 |
| Brochu, G; Candas, B; Cook, PF; Lagueux, J; Ménard, L; Poirier, GG; Potvin, F; Verreault, A | 1 |
| Boulias, C; Moscarello, MA | 1 |
| Hunt, TK; Hussain, MZ | 1 |
| Aepfelbacher, M | 1 |
| Barrett, P; Davidson, G; Hazlerigg, D; Lawson, W; MacLean, A; Milligan, G; Morgan, PJ | 1 |
| Hashimoto, Y; Iizuka, H; Takahashi, H; Tamura, T; Tsutsui, M | 1 |
| Hoshino, S; Kanaho, Y; Katada, T; Maehama, T; Nishina, H | 1 |
| Kuemmerle, JF; Makhlouf, GM | 1 |
| Abramson, SB; Amin, A; Clancy, R; Leszczynska, J; Levartovsky, D | 1 |
| Aboul-Ela, N; Hanson, K; Jacobson, MK; Wu, MC | 1 |
| Galione, A; Potter, BV; Turner, M; Watson, SP; White, A; Willmott, N | 1 |
| Brown, DA; Egorova, A; Higashida, H; Ishizaka, N; Noda, M; Okamoto, H; Robbins, J; Takasawa, S; Taketo, M | 1 |
| Gillison, SL; Komatsu, M; McDermott, AM; Sharp, GW | 1 |
| Moss, J; Zolkiewska, A | 1 |
| Mészáros, LG; Mészáros, V; Socci, R | 1 |
| Sitsapesan, R; Williams, AJ | 1 |
| Bellmann, K; Burkart, V; Kleemann, R; Kolb, H; Radons, J; Wenz, A | 1 |
| Jackson, TM; Kirkland, JB; Rawling, JM; Roebuck, BD | 1 |
| Domenighini, M; Magagnoli, C; Pizza, M; Rappuoli, R | 1 |
| Calder, L; De Flora, A; Franco, L; Guida, L; Zocchi, E | 1 |
| Ginnan, R; Rahmatullah, M; Robishaw, JD | 1 |
| Campana, D; Coustan-Smith, E; Evans, WE; Kumagai, M; Malavasi, F; Murray, DJ; Murti, KG; Silvennoinen, O | 1 |
| Grassie, MA; Milligan, G | 1 |
| Faraone-Mennella, MR; Farina, B | 1 |
| Coulter, LJ; Hide, G | 1 |
| McDonald, LJ; Moss, J | 4 |
| Alvarez-Gonzalez, R | 1 |
| Lee, HC | 2 |
| Bector, N; Dhalla, NS; Jasmin, G; Nagano, M; Sethi, R; Takeda, N | 1 |
| Beers, KW; Chini, EN; Dousa, TP; Lee, HC | 1 |
| Gimmel'brant, AA | 1 |
| Howlett, A; Klein, C; Tao, Y | 1 |
| Fruen, BR; Louis, CF; Mickelson, JR; Shomer, NH; Velez, P | 1 |
| Inanobe, A; Katada, T; Kobayashi, I; Kontani, K; Nishina, H; Ohoka, Y; Takahashi, K | 1 |
| Haun, RS; Lee, FJ; Moss, J; Price, SR; Tsai, SC; Vaughan, M; Welsh, CF | 1 |
| Carty, DJ | 1 |
| Dhanasekaran, N; Ruoho, AE; Vaillancourt, RR | 1 |
| Goberna, R; Lucas, M; Sánchez-Margalet, V | 1 |
| Dritschilo, A; Prasad, S; Walent, J | 1 |
| Muller-Steffner, H; Muzard, M; Oppenheimer, N; Schuber, F | 1 |
| Asano, T; Fukada, Y; Matsuda, T; Murata, M; Shimonishi, Y; Takao, T; Yoshizawa, T | 1 |
| Clark, MA; Egan, RW; Korte, A | 1 |
| Rout, UK; Weiner, H | 1 |
| Hoshino, S; Ikeda, K; Inageda, K; Katada, T; Nishina, H; Takahashi, K | 1 |
| Couvineau, A; Daviaud, D; Denis, C; Devedjian, JC; Drean, G; Planat, V; Salomon, R; Senard, JM; Valet, P; Voisin, T | 1 |
| Choe, S; Falnes, PO; Madshus, IH; Olsnes, S; Wilson, BA | 1 |
| Barbançon-Finck, V; Barbieri, JT; Xu, Y | 1 |
| Bermek, E; Nurten, R; Sayhan, N; Ustündağ, I | 1 |
| Blanke, SR; Collier, RJ; Covacci, A; Huang, K; Papini, E; Wilson, BA | 1 |
| Garcia, JG; Patterson, CE | 1 |
| Aktories, K; Just, I; Moss, J; Wollenberg, P | 1 |
| Böhm, M; Erdmann, E; Gierschik, P; Knorr, A; Schmidt, U; Weismann, K | 1 |
| Bazan, JF; Grimaldi, JC; Howard, M; Lee, HC; Lund, FE; Parkhouse, RM; Santos-Argumedo, L; Walseth, TF | 1 |
| Galione, A; Jackson, DG; Summerhill, RJ | 1 |
| Fong, JC; Lin, JH; Pan, JT; Wang, FF; Wang, HY | 1 |
| Klein, JB; Lederer, ED; McLeish, KR | 1 |
| Artamonov, ID; Lipkin, VM; Petrov, VM | 1 |
| Bannykh, S; Colanzi, A; Corda, D; De Matteis, MA; Di Girolamo, M; Di Tullio, G; McDonald, LJ; Moss, J; Pallas, M; Santini, G | 1 |
| Kanaho, Y; Katada, T; Takahashi, K; Takei, Y | 1 |
| Nishikori, Y; Shimoyama, M; Tsuchiya, M; Yamada, K | 1 |
| Chypre, C; Hog, F; Jesser, M; Leterrier, JF; Mandel, P | 1 |
| Fischetti, VA; Pancholi, V | 1 |
| McLeish, KR; Schepers, TM | 1 |
| Boyer, CS; Moldéus, P; Moore, GA | 1 |
| Cullen, G; Dolphin, AC; Fazeli, MS; Huston, E; Pearson, H; Sweeney, MI | 1 |
| Aranda, A; Pascual, A; Perez, P; Sanchez-Pacheco, A; Villa, A | 1 |
| Jacobs, AA; McLeish, KR | 1 |
| Culver, GM; Kierzek, R; LaReau, RD; McCraith, SM; Michaud, N; Phizicky, EM; Turner, DH; Zillmann, M | 1 |
| An, NH; Han, MK; Kim, HR; Kim, UH; Park, BH | 1 |
| Govitrapong, P; Lee, NM; Loh, HH; Zhang, X | 1 |
| Jacobson, EL; Jacobson, MK; Kim, H | 1 |
| Brüne, B; Dimmeler, S | 1 |
| Jacobson, EL; Jacobson, MK | 2 |
| Benatti, U; De Flora, A; Franco, L; Guida, L; Lee, HC; Zocchi, E | 1 |
| Hexum, TD; Zhu, J | 1 |
| Bulargina, TV; Sergienko, EA; Severin, ES | 1 |
| Barbieri, JT; Krueger, KM | 1 |
| Shall, S | 1 |
| Moss, J; Okazaki, IJ; Takada, T; Zolkiewska, A | 1 |
| Antoine, R; Locht, C | 1 |
| Bummer, PM; Cervantes-Laurean, D; Coyle, DL; Jacobson, EL; Jacobson, MK; Strohm, MS | 1 |
| Okamoto, H; Takasawa, S; Tohgo, A | 1 |
| Abe, H; Akabane, A; Kato, I; Nata, K; Suzuki, Y; Takamura, T; Takasawa, S; Tanaka, O; Yonekura, H; Yoshimoto, T | 1 |
| Auguste, P; Baird, A; Boulle, N; Jones, EM | 1 |
| Aktories, K; Hofmann, F; Jung, M; Just, I; van Damme, J; Vandekerckhove, J | 1 |
| Dennert, G; Nemoto, E; Wang, J | 1 |
| Aktories, K; Geipel, U; Just, I | 1 |
| Benos, DJ; Berdiev, BK; Fuller, CM; Ismailov, II; Jovov, B; Keeton, DA | 1 |
| Balasubramanian, S; Bazan, F; Haag, F; Kahlke, D; Kastelein, R; Koch-Nolte, F; Petersen, D; Thiele, HG; Willer, T | 1 |
| Galione, A; Lee, HC; Sethi, JK; Walseth, TF; White, AM; Willmott, N | 1 |
| Bortell, R; Greiner, DL; Kanaitsuka, T; Mordes, JP; Moss, J; Rigby, MR; Rossini, AA; Shigeta, H; Stevens, LA | 1 |
| Bak, J; Galione, A; Genazzani, AA | 1 |
| Benhar, I; Davies, DR; Dyda, F; Li, M; Pastan, I | 1 |
| Cerni, C; Schmid, G; Wesierska-Gadek, J | 1 |
| Aleo, MF; Pompucci, G; Preti, A; Sestini, S | 1 |
| Berggren, PO; Brown, G; Efanov, AM; Islam, MS; Köhler, M; Larsson, O; Webb, DL | 1 |
| Calvo, JR; Carrero, I; Guijarro, LG; Pozo, D; Prieto, JC; Segura, JJ | 1 |
| Adler, KB; Dodam, JR; Olson, NC | 1 |
| Huh, JW; Ochi, K; Shima, J | 1 |
| Chae, SW; Cho, KP; Eun, JS; Han, MK; Kim, UH; Kwak, YG; Park, SK | 1 |
| Augustin, A; Muller-Steffner, HM; Schuber, F | 1 |
| Anis, Y; Cohen-Armon, M; Dekel, N; Hammel, I; Homburg, S | 1 |
| Ensign, JC; Serres, MH | 1 |
| An, NH; Cho, YS; Han, MK; Kim, HR; Kim, UH; Lee, JY; Song, YM | 1 |
| Barile, M; Danese, G; Passarella, S; Quagliariello, E | 1 |
| Graves, DJ; Huiatt, TW; Robson, RM; Sernett, SW; Zhou, H | 1 |
| De Flora, A; Franco, L; Guida, L; Piccini, D; Tacchetti, C; Zocchi, E | 1 |
| Buchlow, G; Griesenbeck, J; Jorcke, D; Mayer-Kuckuk, P; Oei, SL; Wons, T; Ziegler, M | 1 |
| Cachero, TG; Gonzalez, C; Rigual, R; Rocher, A | 1 |
| Grant, KR; Harnett, MM; Harnett, W; Milligan, G | 1 |
| Albeniz, IU; Bermek, E; Nurten, R | 2 |
| Gillison, SL; Sharp, GW; Straub, SG | 1 |
| Bürkle, A; Cziepluch, C; Jauniaux, JC; Küpper, JH; Lichter, P; Meyer, R; Mincheva, A; Poirier, GG; Tobiasch, E; Van Gool, L | 1 |
| Bernardi, R; Poirier, GG; Rossi, L; Scovassi, AI | 1 |
| Grunwald, SK; Ludden, PW | 1 |
| Chini, EN; de Toledo, FG; Dousa, TP; Thompson, MA | 1 |
| Crawford, JH; Scott, RH; Seabrook, GR; Wootton, JF | 1 |
| Mészáros, LG; Váradi, G; Wrenn, RW | 1 |
| Amin, RH; Bondarenko, VA; Desai, M; Dua, S; Hayashi, F; Jackson, KW; Kinumi, T; Komori, N; Lipkin, VM; Matsumoto, H; Ohashi, M; Usukura, J; Yamazaki, A; Yamazaki, M; Yousif, KK | 1 |
| Bortell, R; Greiner, D; Kanaitsuka, T; Mordes, J; Moss, J; Rigby, M; Rossini, A; Stevens, L | 1 |
| Saxty, BA; van Heyningen, S | 1 |
| Di Giulio, AM; Donadoni, ML; Finco, C; Gorio, A | 1 |
| Corda, D; Di Girolamo, M; Iurisci, C; Luini, A; Lupi, R; Silletta, MG; Turacchio, S | 1 |
| Coyle, DL; Jacobson, EL; Jacobson, MK; Tai, HH; Vu, CQ | 1 |
| Campbell, WB; Li, P; Zou, AP | 1 |
| Herrero-Yraola, A; Jorcke, D; Schweiger, M; Ziegler, M | 2 |
| Buchlow, G; Griesenbeck, J; Mayer-Kuckuk, P; Oei, SL; Schweiger, M; Ziegler, M | 1 |
| Scheuring, J; Schramm, VL | 1 |
| Margulis, A; Pozdnyakov, N; Sitaramayya, A | 1 |
| Zhang, J | 1 |
| Coyle, DL; Jacobson, EL; Jacobson, MK; Kim, H; Vu, CQ | 1 |
| De Lucia, F; De Maio, A; Faraone-Mennella, MR; Farina, B; Gambacorta, A; Nicolaus, B | 1 |
| Hagen, T; Ziegler, M | 1 |
| Vinogradov, AD; Zharova, TV | 1 |
| Ashamu, GA; Galione, A; Potter, BV; Sethi, JK | 1 |
| Badruzzaman, M; Hara, N; Shimoyama, M; Terashima, M; Tsuchiya, M | 1 |
| Nadolny, C; Zundel, G | 1 |
| Faivre, JF; Guibert, J; Lahouratate, P | 1 |
| Imai, Y; Kitagawa, T; Tomita, T; Tsuyama, S | 1 |
| Badruzzaman, M; Miyaoka, T; Ohno, T; Shimoyama, M; Terashima, M; Tsuchiya, M; Yamada, K; Yamamori, C | 1 |
| Ishino, H; Itoga, M; Shimoyama, M; Tsuchiya, M | 1 |
| Göpel, SO; Klebl, BM; Pette, D | 1 |
| Colanzi, A; Corda, D; De Matteis, MA; Di Tullio, G; Fiucci, G; Flati, S; Fusella, A; Luini, A; Malhotra, V; Mironov, A; Polishchuk, R; Silletta, MG; Weigert, R | 1 |
| Aarhus, R; Dickey, DM; Lee, HC; Walseth, TF | 1 |
| Hashii, M; Higashida, H; Higashida, M; Noda, M; Ohshima, T; Okamoto, H; Takasawa, S; Takayasu, T; Taketo, M; Yokoyama, S | 1 |
| Masutani, M; Nakagama, H; Noda, T; Nozaki, T; Saito, D; Sugimura, T; Sugiyama, T; Takato, T; Wakabayashi, K | 1 |
| Cabodevilla, JF; Martinez-Irujo, JJ; Mercapide, J; Santiago, E; Villahermosa, ML | 1 |
| Bessman, MJ; Dunn, CA; Frick, DN; O'Handley, SF | 1 |
| Berti, PJ; Scheuring, J; Schramm, VL | 1 |
| Baux, G; Fossier, P; Meunier, FM; Mothet, JP; Stinnakre, J; Tauc, L | 1 |
| Galione, A; Wilson, HL | 1 |
| de Murcia, G; Rolli, V; Ruf, A; Schulz, GE | 1 |
| Albrieux, M; Lee, HC; Villaz, M | 1 |
| Bubis, M; Zisapel, N | 1 |
| Barbieri, JT; Gross, GJ; Hsu, AK; Li, PL; Schultz, JE | 1 |
| Campbell, WB; Li, PL; Zou, AP | 1 |
| Lee, HC; Munshi, C; Sauve, AA; Schramm, VL | 1 |
| Bolognesi, M; Coda, A; Rizzi, M | 1 |
| An, NH; Cha, YS; Cho, YS; Han, MK; Kim, UH; Kwark, OS; Phoe, MS | 1 |
| Bruzzone, S; De Flora, A; Franco, L; Guida, L; Usai, C; Zocchi, E | 2 |
| Dale, B; Galione, A; Marino, M; Russo, GL; Wilding, M | 1 |
| de Lange, T; Giriat, I; Schmitt, A; Smith, S | 1 |
| Budker, T; Chobanian, M; Din, ZZ; Fahien, LA; Laboy, JI; Prabhakar, P; Wang, J | 1 |
| Matsumura, N; Tanuma, S | 1 |
| Kierzek, R; Phizicky, EM; Spinelli, SL; Turner, DH | 1 |
| Bruzzone, S; De Flora, A; Franco, L; Guida, L; Passalacqua, M; Usai, C; Zocchi, E | 1 |
| Howard, MC; Lund, FE; Muller-Steffner, HM; Schuber, F; Stout, CD; Yu, N | 1 |
| Alvarez-Gonzalez, R; Mendoza-Alvarez, H | 1 |
| Colanzi, A; Corda, D; De Matteis, MA; Di Girolamo, M; Fiucci, G; Luini, A; Mironov, A; Santone, I; Silletta, MG; Weigert, R | 1 |
| Hirata, M; Kanematsu, T; Misumi, Y; Takeuchi, H | 1 |
| Andreopoulos, S; Li, PP; Siu, KP; Warsh, JJ | 1 |
| Di Giulio, AM; Germani, E; Gorio, A; Lesma, E | 1 |
| Adebanjo, OA; Anandatheerthavarada, HK; Arakawa, T; Bevis, PJ; Biswas, G; Corisdeo, S; Epstein, S; Hakeda, Y; Koval, A; Kumegawa, M; Lai, FA; Moonga, BS; Moser, AJ; Sodam, B; Sun, L; Troen, BR; Zaidi, M | 1 |
| Kanazawa, T; Kishimoto, T; Kono, T; Koyama, K; Matsushima-Hibiya, Y; Nishisaka, N; Sugimura, T; Wakabayashi, K; Watanabe, M | 1 |
| Kim, HJ; Levine, RL; Moss, J; Thompson, WC; Weng, B | 1 |
| Cheng, J; Chini, EN; Dousa, TP; Liang, M | 1 |
| Okamoto, H | 1 |
| Frenkin, MV; Kotlyar, AB | 1 |
| Adebanjo, OA; Anandatheerthavarada, HK; Avadhani, NG; Bevis, PJ; Biswas, G; Epstein, S; Huang, CL; Koval, AP; Lai, FA; Moonga, BS; Sodam, BR; Sun, L; Zaidi, M | 1 |
| Fischer, GM; Gallyas, F; Kispal, G; Sumegi, B; Szabados, E | 1 |
| Shimoyama, M; Terashima, M; Tsuchiya, M; Yamamori, C | 1 |
| Hashii, M; Higashida, H; Minabe, Y | 1 |
| Coukos, G; Coutifaris, C; Daiter, E; Makrigiannakis, A; Woolkalis, MJ | 1 |
| Strauss, E | 1 |
| Ziegler, M | 1 |
| Corrèze, C; Dib, K; Lambert, B | 1 |
| Corda, D; Di Girolamo, M; Lupi, R | 1 |
| Cho, YS; Han, MK; Kim, UH; Kim, YS; Yim, CY | 1 |
| Heller, RC; Landry, J; Pillus, L; Stebbins, J; Sternglanz, R; Sutton, A; Tafrov, ST | 1 |
| Amorini, AM; Di Pierro, D; Fazzina, G; Galvano, M; Giardina, B; Lazzarino, G; Lupi, A; Tavazzi, B | 1 |
| Kato, I; Nata, K; Noguchi, N; Okamoto, H; Takasawa, S; Tohgo, A | 1 |
| Hara, N; Shimoyama, M; Terashima, M; Tsuchiya, M | 1 |
| Yankovsky, NK; Zdanovskaia, MV; Zdanovsky, AG | 1 |
| Landry, J; Slama, JT; Sternglanz, R | 1 |
| Denu, JM; Landry, J; Sternglanz, R; Tanner, KG | 1 |
| Brusasco, V; Bruzzone, S; Crimi, E; De Flora, A; Franco, L; Guida, L; Song, P; Usai, C; Walseth, TF; Zocchi, E | 1 |
| Moazed, D; Tanny, JC | 1 |
| Guiney, DG; Lesnick, ML | 1 |
| Alvarez-Gonzalez, R; Chavez-Bueno, S; Mendoza-Alvarez, H | 1 |
| Epel, D | 1 |
| Hatakeyama, M; Tono-Oka, S | 1 |
| Kumasaka, S; Okabe, E; Shoji, H | 1 |
| Bruzzone, S; Costa, A; De Flora, A; Franco, L; Guida, L; Usai, C; Zocchi, E | 1 |
| Mariani, P; Navazio, L; Sanders, D | 1 |
| Bakhit, SM; Franke, P; Herrero-Yraola, A; Jorcke, D; Schweiger, M; Weise, C; Ziegler, M | 1 |
| AbdelRaheim, SR; Cartwright, JL; Gasmi, L; McLennan, AG | 1 |
| An, NH; Han, MK; Kim, HK; Kim, UH; Park, BH; Park, BJ; Um, C | 1 |
| Adriouch, S; Haag, F; Koch-Nolte, F; Ohlrogge, W; Seman, M | 1 |
| D'Andrea, P; Franco, L; Moro, L; Padoan, M; Romanello, M; Veronesi, V | 1 |
| Bruzzone, S; De Flora, A; Fedele, E; Matteoli, M; Schenk, U; Verderio, C; Zocchi, E | 1 |
| Bortell, R; Greiner, DL; McKenna, RC; Mordes, JP; Moss, J; Niedzwiecki, D; Patton, WA; Rigby, MR; Rossini, AA; Stevens, LA | 1 |
| Cibulsky, SM; Levitan, IB | 1 |
| Furuichi, K; Inamura, K; Matsushime, H; Miyake, A; Mochizuki, S; Sano, Y; Yokoi, H | 1 |
| Cakir-Kiefer, C; Muller-Steffner, H; Oppenheimer, N; Schuber, F | 1 |
| Deveze-Alvarez, M; Garcı A-Soto, J; Martı Nez-Cadena, G | 1 |
| Habon, T; Halmosi, R; Kesmarky, G; Past, T; Sumegi, B; Szabados, E; Toth, K | 1 |
| Calver, J; Cyr, T; Menzies, AJ; Whitehouse, LW | 1 |
| Kanazawa, T; Koyama, K; Matsushima-Hibiya, Y; Sugimura, T; Takamura-Enya, T; Totsuka, Y; Wakabayashi, K; Watanabe, M | 1 |
| Bisso, A; Bruzzone, S; Contini, P; De Flora, A; Franco, L; Guida, L; Usai, C; Zocchi, E | 1 |
| Barzilai, A; Hammel, I; Hochman, A; Rotman, G; Shiloh, Y; Stern, N; Weizman, N; Zemach, N | 1 |
| Cockayne, DA; Garvy, B; Goodrich, S; Harmsen, A; Howard, M; Jacobson, EL; Kusser, K; Lund, FE; Monard, S; Oppenheimer, N; Partida-Sánchez, S; Randall, TD | 1 |
| Gulyamova, TG; Kerbalaeva, AM; Nasmetova, SM; Ruzieva, DM; Shakirzyanova, MR | 1 |
| Guse, AH; Mayr, GW; Schweitzer, K | 1 |
| Avalos, J; Boeke, JD; Celic, I; Deng, H; Sauve, AA; Schramm, VL | 1 |
| Graeff, R; Lee, HC | 1 |
| Borra, MT; Denu, JM; Foltz, KR; Jackson, MD; Marshall, B; O'Neill, FJ; Verdin, E | 1 |
| Denu, JM; Jackson, MD | 1 |
| Eisfeld, J; Heiner, I; Jüngling, E; Lückhoff, A; Wehage, E; Zitt, C | 1 |
| Boquet, P; Charbonnier, JB; Flatau, G; Gas, F; Le Du, MH; Ménétrey, J; Menez, A; Stura, EA; Teulon, JM | 1 |
| Bell, SD; Chang, JH; Cho, Y; Hwang, KY; Jackson, SP; Kim, HC; Lee, JW | 1 |
| Zakharova, NV | 1 |
| Eisfeld, J; Halaszovich, CR; Heiner, I; Jüngling, E; Lückhoff, A; Wehage, E; Zitt, C | 1 |
| Clark, RS; Dixon, CE; Jenkins, LW; Kochanek, PM; Melick, J; Satchell, MA; Szabó, C; Zhang, X | 1 |
| Bourgeois, C; Cavanaugh, E; Moss, J; Nightingale, M; Okazaki, I | 1 |
| Andris, F; Leo, O; Rongvaux, A; Van Gool, F | 1 |
| Dillon, KJ; Martin, NM; Smith, GC | 1 |
| Landry, J; Sternglanz, R | 1 |
| Sauve, AA; Schramm, VL | 2 |
| Bedalov, A; Hirao, M; Nelson, M; Posakony, J; Simon, JA | 1 |
| Boulla, G; Deterre, P; Lacapère, JJ; Lund, FE; Oppenheimer, N; Primack, J; Schuber, F | 1 |
| Kirkland, JB | 3 |
| Armstrong, S; Merrill, AR | 1 |
| Berger, F; Ramírez-Hernández, MH; Ziegler, M | 1 |
| Avalos, JL; Boeke, JD; Wolberger, C | 1 |
| Becker, HD; Ghani, QP; Hunt, TK; Hussain, MZ; Wagner, S | 1 |
| Chai, X; Harshaw, R; Marmorstein, R; Zhao, K | 1 |
| Gerth, A; Hauschildt, S; Nieber, K; Oppenheimer, NJ | 1 |
| Jackson, JB; Mather, OC; Singh, A; van Boxel, GI; White, SA | 1 |
| Ayub, K; Hallett, MB | 1 |
| Niere, M; Ziegler, M | 1 |
| Gruszczynska-Biegala, J; Zhao, Z; Zolkiewska, A | 1 |
| Akçakaya, H; Aroymak, A; Bektaş, M; Bermek, E; Nurten, R | 1 |
| Chang, MP; Lee, JW; Nakamura, LT; Wisnieski, BJ | 1 |
| Aswad, F; Dennert, G; Kaslow, H; Kawamura, H; Koch-Nolte, F; Leiter, EH; Malone, K; Minagawa, M; Schott, WH | 1 |
| Adriouch, S; Braasch, F; Haag, F; Koch-Nolte, F; Koestner, W; Krebs, C; Leiter, EH; Lund, FE; Oppenheimer, N; Seman, M | 1 |
| Cho, EH; Cho, SW; Choi, MM; Choi, SY; Huh, JW; Lee, HJ; Yang, SJ | 1 |
| Scharenberg, AM | 1 |
| Grunwald, SK; Ludden, PW; Ponnuraj, RK; Rubio, LM | 1 |
| Jambunathan, N; Mahalingam, R | 1 |
| Denu, JM; Smith, BC | 1 |
| Hara, N; Osago, H; Shibata, T; Tsuchiya, M; Yamada, K | 1 |
| FitzGerald, DJ; Pastrana, DV | 1 |
| Kaufmann, SH; Kim, C; Merrill, AR; Slavinskaya, Z | 1 |
| Iqbal, J; Zaidi, M | 1 |
| Alt, FW; Blander, G; Christodoulou, DC; Fahie, K; Guarente, L; Haigis, KM; Haigis, MC; Karow, M; Mostoslavsky, R; Murphy, AJ; Prolla, TA; Valenzuela, DM; Weindruch, R; Wolberger, C; Yancopoulos, GD | 1 |
| Liao, SD; Puro, DG | 1 |
| Asokanathan, C; Coote, JG; Corbel, MJ; Douglas-Bardsley, A; Gomez, SR; Parton, R; Xing, DK; Yuen, CT | 1 |
| Begley, TP; Chatterjee, A; Ealick, SE; Jurgenson, CT; Schroeder, FC | 1 |
| Forouhar, F; Khan, JA; Tao, X; Tong, L | 1 |
| Naziroğlu, M | 2 |
| Ogawa, T; Shigeoka, S; Yabuta, Y; Yoshimura, K | 1 |
| Ge, X; Li, GJ; Wang, SB; Wang, X; Xia, Y; Zhu, H; Zhu, T | 1 |
| Cecchini, G; Grivennikova, VG; Karliner, JS; Kotlyar, AB; Vinogradov, AD | 1 |
| Bracht, A; Bracht, F; Broetto-Biazon, AC; Constantin, J; de Sá-Nakanishi, AB; Kelmer-Bracht, AM; Lopez, CH | 1 |
| Håkansson, K; Liu, H; Yoo, HJ | 1 |
| Lin, H | 1 |
| Bhagat, H; Dammermann, W; Fliegert, R; Gasser, A; Guse, AH; Lund, FE; Mousseau, BJ; Partida-Sanchez, S; Shi, G; Siebrands, CC; Sumoza-Toledo, A; Walseth, TF | 1 |
| Alvarez-Dominguez, C; Carrasco-Marín, E; Del Cerro-Vadillo, E; Fernandez-Prieto, L; Fresno, M; Gomez-Lopez, MT; Leyva-Cobián, F; Madrazo-Toca, F; Pareja, E; Tobes, R; Vandekerckhove, J | 1 |
| Luk, T; Malam, Z; Marshall, JC | 1 |
| Lückhoff, A; Naziroğlu, M | 1 |
| Brautigam, CA; Grishin, NV; Huang, N; Li, X; Magni, G; Osterman, AL; Raffaelli, N; Sorci, L; Zhang, H; Zhang, X | 1 |
| Buelow, B; Scharenberg, AM; Song, Y | 1 |
| Fukusaki, E; Harada, K; Ishikawa, K; Ogawa, T; Shigeoka, S; Yoshimura, K | 1 |
| Bracht, A; Bracht, F; Bracht, L; Broetto-Biazon, AC; Kelmer-Bracht, AM | 1 |
| Rancourt, A; Satoh, MS | 1 |
| Guse, AH; Haag, F; Koch-Nolte, F; Lund, F; Ziegler, M | 1 |
| Du, J; Jiang, H; Lin, H | 1 |
| Adriouch, S; Bannas, P; Haag, F; Koch-Nolte, F; Krebs, C; Rissiek, B; Scheuplein, F; Schwarz, N; Seman, M | 1 |
| De Ingeniis, J; Galeazzi, L; Gelfand, MS; Huang, N; Korostelev, YD; Mancini, C; Raffaelli, N; Rakhmaninova, AB; Rodionov, DA; Zhang, H | 1 |
| Leprêtre, C; Scovassi, AI; Sidoli, G; Torriglia, A | 1 |
| De Gara, L; Foyer, CH; Locato, V; Markovic, J; Pallardó, FV; Pellny, TK; Vivancos, PD | 1 |
| Sauve, AA | 1 |
| Fukusaki, E; Harada, K; Ishikawa, K; Ogawa, T; Shigeoka, S; Tamoi, M; Yoshimura, K | 1 |
| Beneke, S; Bürkle, A; Kunzmann, A; Schmitz, M; Weidele, K | 1 |
| Adam, G; Balcerak, P; Bannas, P; Graumann, O; Haag, F; Hohenberg, H; Ittrich, H; Kaul, MG; Koch-Nolte, F; Peldschus, K | 1 |
| Csanády, L; Tóth, B | 1 |
| Jambunathan, N; Mahalingam, R; Penaganti, A; Tang, Y | 1 |
| Cen, Y; Sauve, AA | 1 |
| Chen, Z; Graeff, R; Hao, Q; Lee, H; Zhang, H; Zhang, L | 1 |
| Denu, JM; Devries, MK; Dong, A; Edwards, AM; Feldman, JL; Pan, PW | 1 |
| Cao, K; Ge, X; Liang, Q; Wang, H | 1 |
| Di Martino, C; Pallotta, ML | 1 |
| Birrell, JA; Hirst, J; King, MS | 1 |
| Chen, Q; Dong, S; Dou, D; Gijzen, M; Kale, SD; Kong, G; Qutob, D; Sui, Y; Tyler, BM; Wang, Y; Yang, X; Yin, W; Zhang, Z; Zheng, X | 1 |
| Chen, Z; Graeff, R; Hao, Q; Kotaka, M; Lee, HC; Zhang, LH | 1 |
| Christmann, J; Marx, R; Mori, Y; Numata, T; Okada, Y; Sato, K; Wehner, F | 1 |
| Aguan, K; Hara, Y; Katano, M; Kiyonaka, S; Miki, T; Mori, Y; Numata, T; Sawamura, S; Suzuki, T; Yamakawa, K; Yamamoto, S | 1 |
| Durnin, L; Hwang, SJ; Mutafova-Yambolieva, VN; Sanders, KM; Ward, SM | 1 |
| Aravind, L; de Souza, RF | 1 |
| de Figueiredo, LF; Gossmann, TI; Heiland, I; Puntervoll, P; Schuster, S; Ziegler, M | 1 |
| Adriouch, S; Boyer, O; Drouot, L; Fliegert, R; Guse, AH; Haag, F; Koch-Nolte, F; Nicke, A; Schwarz, N | 1 |
| Ge, X; Liu, P; Lu, Y; Wang, H; Wen, W; Xia, Y; Zhang, J | 1 |
| Katada, T | 1 |
| Haag, F; Hurwitz, R; Koch-Nolte, F; Lischke, T; Mittrücker, HW; Schumacher, V; Wesolowski, J | 1 |
| Dölle, C; Rack, JG; Ziegler, M | 1 |
| Birrell, JA; Hirst, J | 1 |
| Beccari, AR; Bolognesi, M; Bruno, A; Catara, G; Cericola, C; Colanzi, A; Corda, D; De Flora, A; Grimaldi, G; Lalioti, VS; Liberali, P; Luini, A; Nardini, M; Ronci, M; Urbani, A; Valente, C | 1 |
| Cialabrini, L; Kazanov, MD; Mazzola, F; Orsomando, G; Osterman, AL; Raffaelli, N; Ruggieri, S; Sorci, L | 1 |
| Gertz, M; Nguyen, GT; Schaefer, S; Steegborn, C; Weyand, M | 1 |
| Beneke, S; Berndt, S; Bürkle, A; Ebert, F; Leffers, L; Mangerich, A; Schwerdtle, T; Weber, T | 1 |
| Shimizu, M; Takaya, N | 1 |
| Braidy, N; Chan-Ling, T; Grant, R; Guillemin, GJ; Jayasena, T; Mansour, H; Poljak, A; Sachdev, P; Smythe, G | 1 |
| Durnin, L; Mutafova-Yambolieva, VN | 1 |
| Hottiger, MO; Rosenthal, F | 1 |
| Bailey, SM; Udoh, US; Young, ME | 1 |
| Adriouch, S; Boyer, O; Haag, F; Koch-Nolte, F; Rissiek, B | 1 |
| Raffaelli, N; Ruggieri, S; Sorci, L | 1 |
| Balducci, E; Biagini, M; Castagnini, M; Picchianti, M; Russo, C; Soldaini, E | 1 |
| Leung, AK; Vivelo, CA | 1 |
| Guse, AH | 2 |
| Arnold, FH; Brinkmann-Chen, S; Buller, AR; Cahn, JK; Einsle, O; Hu, Y; Ribbe, MW; Spatzal, T; Wiig, JA | 1 |
| Csanády, L; Iordanov, I; Tóth, B | 1 |
| Toda, A; Tsuge, H; Tsumori, Y; Tsurumura, T; Yoshida, T | 1 |
| Kraus, WL | 1 |
| Hottiger, MO | 1 |
| Bannas, P; Haag, F; Jakoby, T; Koch-Nolte, F; Menzel, S; Miksiewicz, M; Nissen, M; Rissiek, B; Schwarz, N; Tholey, A | 1 |
| Einsle, O; Gerhardt, S; Jung, M; Rumpf, T | 1 |
| Das, C; Liu, X; Luo, ZQ; Nakayasu, ES; Qiu, J; Sheedlo, MJ; Tan, Y; Yu, K | 1 |
| Kraus, WL; Ryu, KW | 1 |
| Barneveld, AV; Dethlefsen, S; Munder, A; Okon, E; Pelnikevich, A; Tümmler, B | 1 |
| Brown, EN; Ferraro, DJ; Plapp, BV; Ramaswamy, S; Rubach, JK; Savarimuthu, BR | 1 |
| Ahel, I; Munnur, D | 1 |
| Bütepage, M; Eckei, L; Krieg, S; Lüscher, B; Shilton, BH; Verheugd, P | 1 |
| Chang, P; Cohen, MS | 1 |
| Lynch, JH; Raffaelli, N; Roje, S; Sa, N; Saeheng, S | 1 |
| Bütepage, M; Eckei, L; Krieg, S; Li, J; Lüscher, B; Rossetti, G; Verheugd, P | 1 |
| Ahel, I; Jankevicius, G; Posavec Marjanovic, M | 1 |
| Haag, F; Koch-Nolte, F; Lukowiak, M; Magnus, T; Rissiek, B | 1 |
| Broom-Peltz, B; Chen, JCH; González, JM; Marti-Arbona, R; Unkefer, CJ | 1 |
| Abdullahu, L; Banerjee, A; Damha, MJ; Goldgur, Y; Munir, A; Shuman, S | 1 |
| Luo, ZQ; Qiu, J | 1 |
| Aesaert, S; Coussens, G; Demuynck, K; Dhondt, S; Inzé, D; Nelissen, H; Neyt, P; Njuguna, E; Paul, L; Storme, V; Van Haver, Y; Van Lijsebettens, M; Vanhaeren, H | 1 |
| Ahel, I; Bartlett, E; Cohen, MS; Kirby, IT; Mikoč, A; Mikolčević, P; Munnur, D; Rack, JGM | 1 |
| Li, P; Liu, S; Liu, Y; Wang, D; Wei, W; Yang, H; Zhang, Y | 1 |
| Grüter, P; Hopp, AK; Hottiger, MO | 1 |
| Aybar, D; Beck, C; Brendes, A; Chang, P; Church, WD; Kuntz, KW; Majer, CR; Prahm, M; Schenkel, LB; Swinger, KK; Vasbinder, MM; Wegener, D; Wigle, TJ | 1 |
| Elnenaei, MO; Gujar, SA; Kennedy, BE; Reiman, A; Sadek, M | 1 |
| Chen, Y; Cho, GJ; Choi, HS; Chung, HT; Joe, Y; Kim, HJ; Kim, UH; Park, J; Park, JW; Rah, SY; Ryter, SW; Ryu, J | 1 |
| Kulikova, VA; Nikiforov, AA | 1 |
| Alhammad, YMO; Brenner, C; Cohen, MS; Fehr, AR; Heer, CD; Perlman, S; Sanderson, DJ; Schmidt, MS; Trammell, SAJ; Voth, LS | 1 |
| Bai, L; Cui, Y; Guo, Y; Li, L; Li, X; Li, XD; Lin, J; Tian, G; Wang, J; Zhang, L; Zhu, A; Zhu, G | 1 |
| Lieber, MR; Naila, T; Tomkinson, AE; Zhao, B | 1 |
| Heney, KA; Lidster, T; Lyons, B; Merrill, AR; Vatta, M | 1 |
| Chang, CF; Chien, CY; Chiu, YC; Cho, CC; Hsu, CH; Huang, YP; Lin, MH | 1 |
| Blank-Landeshammer, B; Hesse, J; Idel, S; Reinders, Y; Rosse, MK; Schrader, J; Sickmann, A; Steckel, B; Sträter, N | 1 |
| Höllmüller, E; Lehner, M; Marx, A; Mertes, B; Rieth, S; Spliesgar, D; Stengel, F | 1 |
| Beddoe, T; Littler, DR; Pulliainen, AT; Rossjohn, J; Sakari, M; Tran, MT | 1 |
| Da'Dara, AA; Nation, CS; Skelly, PJ | 1 |
| Carnero, A; Navas, LE | 1 |
| Chea, C; Ishiwata-Endo, H; Kato, J; Koike, K; Lee, DY; Moss, J; Yamashita, S | 1 |
| Eriksson, LA; Gholami, A; Mahdizadeh, SJ; Minai-Tehrani, D; Saenz-Mendez, P | 1 |
| Gong, J; Li, S; Li, X; Liu, X; Wang, J; Wu, C; Yan, Z; Yang, X; Zhou, H | 1 |
| Dantuluri, S; Jacewicz, A; Shuman, S | 1 |
| Borst, A; Breuer, R; Gomes-Filho, JV; Höfer, K; Jäschke, A; Morales-Filloy, HG; Paczia, N; Pozhydaieva, N; Randau, L; Soppa, J | 1 |
52 review(s) available for nad and adenosine diphosphate ribose
| Article | Year |
|---|---|
Enhancement of cholera toxin-catalyzed ADP-ribosylation by guanine nucleotide-binding proteins.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Bacterial Toxins; Carbohydrate Sequence; Cholera Toxin; Consensus Sequence; Cyclic AMP; Enterotoxins; Escherichia coli Proteins; GTP-Binding Proteins; Humans; Intestinal Mucosa; Mammals; Molecular Sequence Data; NAD; Poly(ADP-ribose) Polymerases; Saccharomyces cerevisiae; Second Messenger Systems; Sequence Homology, Nucleic Acid; Species Specificity; Stimulation, Chemical | 1992 |
Diphtheria toxin and Pseudomonas aeruginosa exotoxin A: active-site structure and enzymic mechanism.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Bacterial Toxins; Binding Sites; Catalysis; Corynebacterium diphtheriae; Diphtheria Toxin; Exotoxins; Models, Molecular; Molecular Sequence Data; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerases; Protein Conformation; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Structure-Activity Relationship; Virulence Factors | 1992 |
Clinical implications of guanine nucleotide-binding proteins as receptor-effector couplers.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Bordetella pertussis; Cholera; Cyclic AMP; Diarrhea; GTP-Binding Proteins; Guanine Nucleotides; Humans; In Vitro Techniques; Membrane Proteins; Models, Biological; NAD; Pseudohypoparathyroidism; Retinitis Pigmentosa; Rod Cell Outer Segment; Transducin; Whooping Cough | 1985 |
ADP-ribosylation reactions.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Nucleus; Chromosomal Proteins, Non-Histone; DNA Repair; Histones; Humans; NAD; NAD+ Nucleosidase; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Rats | 1982 |
ADP-ribosyl transferase, rearrangement of DNA, and cell differentiation.
Topics: 5-Methylcytosine; Adenosine Diphosphate Ribose; Animals; Cell Differentiation; Cell Nucleus; Cytosine; DNA; DNA Repair; DNA, Superhelical; Gene Expression Regulation; Humans; Muscles; NAD; Nucleic Acid Conformation; Nucleotidyltransferases; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Biosynthesis; T-Lymphocytes; Translocation, Genetic; Trypanosoma; Xenopus laevis | 1983 |
Differentiation of the uterus in preparation for gestation: a model for the action of progesterone.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Animals; Cell Differentiation; Decidua; Embryonic Development; Estrone; Estrus; Female; NAD; NADP; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Pregnancy; Progesterone; Rats; Uterus | 1984 |
Nitric oxide and NAD-dependent protein modification.
Topics: Adenosine Diphosphate Ribose; Glyceraldehyde-3-Phosphate Dehydrogenases; NAD; Nitric Oxide; Poly(ADP-ribose) Polymerases | 1994 |
Enzymatic and nonenzymatic ADP-ribosylation of cysteine.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Cysteine; Molecular Structure; NAD; Nitric Oxide; Pertussis Toxin; Poly(ADP-ribose) Polymerases; Substrate Specificity; Virulence Factors, Bordetella | 1994 |
Cyclic ADP-ribose: a calcium mobilizing metabolite of NAD+.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cyclic ADP-Ribose; Humans; Membrane Glycoproteins; Molecular Structure; N-Glycosyl Hydrolases; NAD; Receptors, Cell Surface | 1994 |
ADP-ribosylation reactions.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Bacterial Toxins; DNA; DNA Repair; GTP-Binding Proteins; Humans; NAD; Poly(ADP-ribose) Polymerases | 1995 |
Characterization of mammalian ADP-ribosylation cycles.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Animals; Arginine; Bacterial Toxins; Binding Sites; Conserved Sequence; Erythrocytes; Glycoside Hydrolases; Humans; Mammals; Mice; Molecular Sequence Data; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Rabbits; Rats; Sequence Homology, Amino Acid; Turkeys | 1995 |
A proposed mechanism of ADP-ribosylation catalyzed by the pertussis toxin S1 subunit.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Bacterial Toxins; Binding Sites; Bordetella pertussis; GTP-Binding Proteins; NAD; Pertussis Toxin; Recombinant Fusion Proteins; Substrate Specificity; Virulence Factors, Bordetella | 1995 |
NAD glycohydrolases and the metabolism of cyclic ADP-ribose.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Humans; NAD; NAD+ Nucleosidase; Signal Transduction | 1995 |
New aspects of the physiological significance of NAD, poly ADP-ribose and cyclic ADP-ribose.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Aplysia; Cyclic ADP-Ribose; Endoplasmic Reticulum; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Glycoproteins; Mice; Models, Biological; Molecular Sequence Data; N-Glycosyl Hydrolases; NAD; Poly Adenosine Diphosphate Ribose; Rats; Sequence Homology, Amino Acid | 1995 |
Modulatory role of GTP-binding proteins in the endogenous ADP-ribosylation of cytosolic proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Cytosol; GTP-Binding Proteins; Humans; NAD; NAD+ Nucleosidase; Proteins; Pyrophosphatases; Rats | 1997 |
Intramolecular ADP-ribose transfer reactions and calcium signalling. Potential role of 2'-phospho-cyclic ADP-ribose in oxidative stress.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cattle; Cyclic ADP-Ribose; NAD; NADP; Oxidative Stress; Signal Transduction | 1997 |
Calcium signaling by cyclic ADP-ribose and NAADP. A decade of exploration.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Humans; Models, Molecular; NAD; Signal Transduction | 1998 |
["The CD38-cyclic ADP-ribose signal system": molecular mechanism and biological significance].
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cyclic ADP-Ribose; Insulin; Insulin Secretion; Islets of Langerhans; Microsomes; NAD; NAD+ Nucleosidase; Ryanodine Receptor Calcium Release Channel; Signal Transduction | 1999 |
New functions of a long-known molecule. Emerging roles of NAD in cellular signaling.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Animals; Bacterial Toxins; Calcium Signaling; Cyclic ADP-Ribose; Eukaryotic Cells; Heterotrimeric GTP-Binding Proteins; Humans; Mitochondria; NAD; NADP; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Signal Transduction | 2000 |
Topology of CD38.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Biological Transport; Calcium; Cyclic ADP-Ribose; Homeostasis; Humans; Membrane Glycoproteins; NAD; NAD+ Nucleosidase; Sulfhydryl Compounds | 2000 |
Physiological and pathological significance of the CD38-cyclic ADP-ribose signaling system.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic ADP-Ribose; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Glycoproteins; Molecular Sequence Data; Multienzyme Complexes; NAD; NAD+ Nucleosidase | 2000 |
The best defense is a good offense--Salmonella deploys an ADP-ribosylating toxin.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Motifs; Amino Acid Sequence; Bacterial Toxins; Conserved Sequence; Endotoxins; Enterotoxins; NAD; Salmonella; Sequence Homology, Amino Acid; Virulence Factors | 2001 |
Reconstructing eukaryotic NAD metabolism.
Topics: Adenosine Diphosphate Ribose; Animals; Eukaryotic Cells; Humans; NAD; Tryptophan | 2003 |
Niacin and carcinogenesis.
Topics: Adenosine Diphosphate Ribose; Animals; Apoptosis; DNA Repair; Humans; NAD; Neoplasms; Niacin; Nutritional Status; Poly(ADP-ribose) Polymerases; Skin Neoplasms; Tumor Suppressor Protein p53 | 2003 |
The new life of a centenarian: signalling functions of NAD(P).
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Eukaryotic Cells; Humans; Life Expectancy; Models, Biological; Molecular Structure; NAD; NADP; Signal Transduction | 2004 |
SIR2: the biochemical mechanism of NAD(+)-dependent protein deacetylation and ADP-ribosyl enzyme intermediates.
Topics: Acetylation; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Catalysis; Histone Deacetylases; Hydrolysis; Kinetics; Models, Molecular; NAD; Niacinamide; O-Acetyl-ADP-Ribose; Protein Processing, Post-Translational; Protein Structure, Tertiary; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins | 2004 |
NAD+ surfaces again.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Humans; NAD; Signal Transduction | 2004 |
TRPM2 and TRPM7: channel/enzyme fusions to generate novel intracellular sensors.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Humans; Magnesium; Mitochondria; NAD; Phosphotransferases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Quaternary; Protein Structure, Tertiary; Pyrophosphatases; TRPM Cation Channels | 2005 |
Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery.
Topics: Acrylamides; Adenosine Diphosphate Ribose; Aging; Animals; Antineoplastic Agents; Autoimmune Diseases; Clinical Trials, Phase II as Topic; Cyclic ADP-Ribose; DNA Damage; Drug Design; Enzyme Inhibitors; Humans; Kynurenine; Mice; NAD; Neoplasms; Neurodegenerative Diseases; Neuroprotective Agents; Piperidines; Poly Adenosine Diphosphate Ribose; Signal Transduction; Sirtuins; Tryptophan | 2007 |
New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose.
Topics: Adenosine Diphosphate Ribose; Animals; Antioxidants; Calcium Signaling; Humans; NAD; Oxidative Stress; Reactive Oxygen Species; TRPM Cation Channels | 2007 |
[Regulation mechanism of the intercellular redox status involved in the response to environmental stress in higher plants].
Topics: Adenosine Diphosphate Ribose; Ascorbic Acid; DNA Damage; DNA Repair; Environment; Gene Expression Regulation, Plant; NAD; Oxidation-Reduction; Oxidative Stress; Plant Physiological Phenomena; Plants; Reactive Oxygen Species | 2007 |
Nicotinamide adenine dinucleotide: beyond a redox coenzyme.
Topics: Adenosine Diphosphate Ribose; Animals; Humans; Models, Molecular; Molecular Conformation; NAD; Oxidation-Reduction | 2007 |
Pre-B cell colony-enhancing factor (PBEF)/visfatin: a novel mediator of innate immunity.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Crystallography, X-Ray; Cytokines; Gene Expression Regulation; Humans; Immunity, Innate; Inflammation; Lymphocyte Activation; Lymphocytes; Models, Molecular; Molecular Sequence Data; NAD; Nicotinamide Phosphoribosyltransferase; Polymorphism, Genetic; Regulatory Sequences, Nucleic Acid; Sirtuins | 2008 |
Emerging roles of NAD+ and its metabolites in cell signaling.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Physiological Phenomena; Energy Metabolism; Humans; NAD; NADP; Niacinamide; Second Messenger Systems; Signal Transduction | 2009 |
Sirtuin chemical mechanisms.
Topics: Acetylation; Adenosine Diphosphate Ribose; Animals; Benzimidazoles; Humans; Imidoesters; Lysine; Models, Biological; Molecular Structure; NAD; Niacinamide; Plasmodium falciparum; Saccharomyces cerevisiae; Sirtuins; Trypanosoma brucei brucei | 2010 |
TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channel Blockers; Ganglia, Spinal; Hippocampus; Humans; NAD; Nervous System Diseases; Neuroglia; Neurons; Oxidative Stress; Protein Isoforms; TRPM Cation Channels | 2011 |
The inhibitory G protein G(i) identified as pertussis toxin-catalyzed ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic alpha-2 Receptor Antagonists; Animals; Cell Membrane; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Humans; Insulin; Islets of Langerhans; NAD; Pertussis Toxin; Signal Transduction | 2012 |
NAD and ADP-ribose metabolism in mitochondria.
Topics: Acetylation; Adenosine Diphosphate Ribose; Animals; Humans; Mitochondria; Mitochondrial Proteins; NAD; Protein Processing, Post-Translational; Sirtuin 3; Sirtuins | 2013 |
The purinergic neurotransmitter revisited: a single substance or multiple players?
Topics: Adenosine; Adenosine Diphosphate Ribose; Adenosine Triphosphate; NAD; Nervous System Physiological Phenomena; Purines; Receptors, Purinergic; Synaptic Transmission; Synaptic Vesicles | 2014 |
Identification of ADP-ribosylated peptides and ADP-ribose acceptor sites.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acids; Binding Sites; Humans; N-Glycosyl Hydrolases; NAD; Peptides; Protein Processing, Post-Translational; Proteins | 2014 |
Circadian regulation of metabolism.
Topics: Acetylglucosamine; Adenosine Diphosphate Ribose; Alcohol Drinking; Amino Acids; AMP-Activated Protein Kinases; Animals; Carbohydrate Metabolism; Circadian Clocks; Circadian Rhythm; Diabetes Mellitus; Energy Metabolism; Heme; Homeostasis; Humans; Light; Lipid Metabolism; Mitochondria; NAD; Obesity; Proteins; Sleep; Sleep Disorders, Circadian Rhythm; Suprachiasmatic Nucleus; Wakefulness | 2014 |
ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Cell Death; Humans; Mice; NAD; Natural Killer T-Cells; Receptors, Purinergic P2X7; T-Lymphocytes, Regulatory | 2015 |
NAD homeostasis in the bacterial response to DNA/RNA damage.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bacteria; DNA Damage; DNA Ligases; DNA, Bacterial; Group III Histone Deacetylases; Homeostasis; NAD; Niacinamide; RNA, Bacterial | 2014 |
Calcium mobilizing second messengers derived from NAD.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Humans; NAD; NADP; Second Messenger Systems | 2015 |
ADP-Ribosylation, a Multifaceted Posttranslational Modification Involved in the Control of Cell Physiology in Health and Disease.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; ADP-Ribosylation; Cell Death; DNA Damage; Humans; Hydrolases; NAD; Signal Transduction; Substrate Specificity | 2018 |
Insights into the biogenesis, function, and regulation of ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; ADP-Ribosylation; Bacteria; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Humans; Kinetics; NAD; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Conformation; Protein Processing, Post-Translational | 2018 |
Vitamin B3 in Health and Disease: Toward the Second Century of Discovery.
Topics: Adenosine Diphosphate Ribose; Humans; NAD; Niacin; Niacinamide | 2018 |
Regulation of Glucose Metabolism by NAD
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation; Animals; Carbohydrate Metabolism; Cell Line; DNA Damage; Glucose; Humans; Metabolic Networks and Pathways; Mice; NAD; Organelles | 2019 |
Role of NUDIX Hydrolases in NAD and ADP-Ribose Metabolism in Mammals.
Topics: Adenosine Diphosphate Ribose; Animals; Escherichia coli; Humans; Intracellular Space; Mammals; NAD; Nudix Hydrolases; Oxidation-Reduction; Pyrophosphatases; Saccharomyces cerevisiae; Substrate Specificity | 2020 |
Nicotinamide Adenine Dinucleotide (NAD) Metabolism as a Relevant Target in Cancer.
Topics: Adenosine Diphosphate Ribose; Humans; NAD; Neoplasms; Poly(ADP-ribose) Polymerases; Sirtuins | 2022 |
ARH Family of ADP-Ribose-Acceptor Hydrolases.
Topics: Adenosine Diphosphate Ribose; Animals; Apoptosis Inducing Factor; Arginine; Glycoside Hydrolases; Humans; Hydrogen Peroxide; Hydrolysis; Mice; Mice, Knockout; NAD; O-Acetyl-ADP-Ribose; Poly(ADP-ribose) Polymerase Inhibitors | 2022 |
Enzymology of Ca
Topics: Adenosine Diphosphate Ribose; Glycoside Hydrolases; NAD; NAD+ Nucleosidase; NADPH Oxidases; Second Messenger Systems | 2023 |
598 other study(ies) available for nad and adenosine diphosphate ribose
| Article | Year |
|---|---|
Nicotinamide adenine dinucleotide is about 44% folded in neutral aqueous solutions.
Topics: Adenosine Diphosphate Ribose; Hydrogen-Ion Concentration; Kinetics; Molecular Conformation; NAD; Water | 1979 |
Substrate specificity and partial purification of a stereospecific NAD- and guanidine-dependent ADP-ribosyltransferase from avian erythrocytes.
Topics: Adenosine Diphosphate Ribose; Animals; Erythrocytes; Guanidines; Kinetics; NAD; Nucleotidyltransferases; Structure-Activity Relationship; Substrate Specificity; Turkeys | 1979 |
NAD glycohydrolase and ADP-ribosyltransferase activities are intrinsic to the A1 peptide of choleragen.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Liver; NAD; NAD+ Nucleosidase; Niacinamide; Nucleotidyltransferases; Rats | 1979 |
Poly(ADPRibose) levels as a function of chick limb mesenchymal cell development as studied in vitro and in vivo.
Topics: Adenine; Adenosine Diphosphate Ribose; Animals; Cell Differentiation; Cell Division; Chick Embryo; Culture Techniques; DNA; Extremities; Muscles; NAD; Nucleoside Diphosphate Sugars; Polymers | 1979 |
ADP-ribosylation of nuclear proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Cycle; Cell Division; Cell Nucleus; HeLa Cells; Histones; Humans; Liver; Liver Neoplasms, Experimental; Mice; NAD; Nucleoside Diphosphate Sugars; Protein Binding; Radioimmunoassay; Rats | 1978 |
Intrinsic ADP-ribose transferase activity versus levels of mono(adp-ribose)protein conjugates in proliferating Ehrlich ascites tumor cells.
Topics: Adenosine Diphosphate Ribose; Animals; Carcinoma, Ehrlich Tumor; Cell Division; DNA, Neoplasm; Kinetics; Mice; Mice, Inbred BALB C; NAD; Neoplasm Proteins; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Oxidation-Reduction | 1979 |
Gs alpha is a substrate for mono(ADP-ribosyl)transferase of NG108-15 cells. ADP-ribosylation regulates Gs alpha activity and abundance.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Blotting, Western; Cholera Toxin; Glioma; GTP-Binding Proteins; Hybrid Cells; Iloprost; Immunosorbent Techniques; NAD; Neuroblastoma; Niacinamide; Substrate Specificity; Tumor Cells, Cultured | 1992 |
Nitric oxide-induced S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase inhibits enzymatic activity and increases endogenous ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Amino Acid Oxidoreductases; Animals; Cytosol; Dithionitrobenzoic Acid; Dithiothreitol; Glyceraldehyde-3-Phosphate Dehydrogenases; Gram-Positive Bacterial Infections; Kinetics; Liver; Macromolecular Substances; Male; NAD; Nitric Oxide; Nitric Oxide Synthase; Nitroso Compounds; Oxidation-Reduction; Propionibacterium acnes; Rats; Rats, Sprague-Dawley | 1992 |
GTP-binding proteins in bovine brain nuclear membranes.
Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Cattle; Cell Fractionation; Cell Membrane; Cerebral Cortex; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine Triphosphate; Microsomes; Molecular Weight; NAD; Nuclear Envelope; Pertussis Toxin; Phosphorus Radioisotopes; Photolysis; Virulence Factors, Bordetella | 1992 |
Investigation of guanine-nucleotide-binding protein involvement and regulation of cyclic AMP metabolism in interleukin 1 signal transduction.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Interleukin-1; Kinetics; Membrane Proteins; NAD; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; Signal Transduction; Virulence Factors, Bordetella | 1992 |
The effect of streptozotocin diabetes on the vasoactive intestinal peptide receptor/effector system in membranes from rat ventral prostate.
Topics: Adenosine Diphosphate Ribose; Animals; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Male; Membranes; NAD; Prostate; Rats; Rats, Wistar; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Vasoactive Intestinal Peptide | 1992 |
Regulation of retinal cGMP cascade by phosducin in bovine rod photoreceptor cells. Interaction of phosducin and transducin.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Brain; Cattle; Chromatography, High Pressure Liquid; Cyclic GMP; Eye Proteins; GTP Phosphohydrolases; GTP-Binding Protein Regulators; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Molecular Sequence Data; NAD; Pertussis Toxin; Phosphoproteins; Protein Binding; Rod Cell Outer Segment; Sequence Homology, Amino Acid; Transducin; Virulence Factors, Bordetella | 1992 |
ADPRibosylation of chicken red cell tubulin and inhibition of microtubule self-assembly in vitro by the NAD(+)-dependent avian ADPRibosyl transferase.
Topics: Adenosine Diphosphate Ribose; Alkaloids; Animals; Chickens; Erythrocytes; Kinetics; Microtubules; NAD; Paclitaxel; Poly(ADP-ribose) Polymerases; Tubulin; Turkeys | 1992 |
Gs and Gi protein subunits during cell differentiation in intestinal crypt-villus axis: regulation at the mRNA level.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Alkaline Phosphatase; Animals; Blotting, Northern; Blotting, Western; Cell Differentiation; Cholera Toxin; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Epithelial Cells; Epithelium; Gene Expression Regulation; GTP-Binding Proteins; Intestinal Mucosa; Jejunum; Macromolecular Substances; Male; Membrane Proteins; Molecular Weight; NAD; Pertussis Toxin; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Sucrase; Transcription, Genetic; Virulence Factors, Bordetella | 1992 |
G-proteins and hormonal inhibition of insulin secretion from HIT-T15 cells and isolated rat islets.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cell Line; Cricetinae; Epinephrine; Glipizide; Glucose; GTP-Binding Proteins; In Vitro Techniques; Islets of Langerhans; Kinetics; Mesocricetus; Models, Biological; NAD; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Somatostatin; Virulence Factors, Bordetella | 1992 |
Characterization of the role of lysine 110 of NADH-cytochrome b5 reductase in the binding and oxidation of NADH by site-directed mutagenesis.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Base Sequence; Cattle; Cytochrome Reductases; Cytochrome-B(5) Reductase; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligonucleotides; Oxidation-Reduction; Protein Binding; Sequence Homology, Amino Acid | 1992 |
Nitric oxide stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Binding Sites; Brain; Cysteine; Cytosol; Glyceraldehyde-3-Phosphate Dehydrogenases; Molecular Sequence Data; NAD; Nitric Oxide; Rats | 1992 |
Presence and turnover of adenosine diphosphate ribose in human erythrocytes.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Erythrocytes; Hemoglobins; Humans; Kinetics; NAD; Phosphates; Phosphorus Radioisotopes; Radioisotope Dilution Technique | 1992 |
The thyroid hormone response element is required for activation of the growth hormone gene promoter by nicotinamide analogs.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Growth Hormone; NAD; Niacinamide; Promoter Regions, Genetic; Rats; Receptors, Thyroid Hormone; Recombinant Proteins; Transcription, Genetic; Transfection; Triiodothyronine | 1992 |
Structural consequences of sequence patterns in the fingerprint region of the nucleotide binding fold. Implications for nucleotide specificity.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Enzymes; Glycine; Humans; Hydrogen Bonding; Molecular Sequence Data; NAD; Nucleic Acid Conformation; Nucleotides; Phosphates; Protein Conformation; Substrate Specificity | 1992 |
Pertussis toxin-catalyzed ADP-ribosylation of G(o) alpha with mutations at the carboxyl terminus.
Topics: Adenosine Diphosphate Ribose; Animals; Base Sequence; Cattle; Cloning, Molecular; Escherichia coli; Genetic Vectors; GTP-Binding Proteins; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligodeoxyribonucleotides; Pertussis Toxin; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Retina; Substrate Specificity; Transducin; Virulence Factors, Bordetella | 1992 |
Nitric oxide causes ADP-ribosylation and inhibition of glyceraldehyde-3-phosphate dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Blood Platelets; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Kinetics; Molecular Weight; Molsidomine; NAD; Nitric Oxide; Vasodilator Agents | 1992 |
K-ras transformation greatly increases the toxin-dependent ADP-ribosylation of GTP binding proteins in thyroid cells. Involvement of an inhibitor of the ADP-ribosylation reaction.
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cattle; Cell Line, Transformed; Cell Membrane; Cell Transformation, Neoplastic; Cholera Toxin; Genes, ras; GTP-Binding Proteins; Humans; Kinetics; Macromolecular Substances; Membrane Proteins; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Thyroid Gland; Virulence Factors, Bordetella | 1992 |
Effects of phospholipid and GTP on recombinant ADP-ribosylation factors (ARFs). Molecular basis for differences in requirements for activity of mammalian ARFs.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cattle; Chromatography, Gel; Cloning, Molecular; DNA; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutathione Transferase; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Molecular Weight; NAD; Oligodeoxyribonucleotides; Phospholipids; Recombinant Fusion Proteins; Recombinant Proteins | 1992 |
The rapid response of isolated mitochondrial particles to 0.1 nM-tri-iodothyronine correlates with the ADP-ribosylation of a single inner-membrane protein.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Animals; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Hypothyroidism; Kinetics; Male; Membrane Proteins; Mitochondria, Liver; NAD; Niacinamide; Oxygen Consumption; Propylthiouracil; Rats; Rats, Inbred Strains; Triiodothyronine | 1992 |
NADPH: a stimulatory cofactor for nitric oxide-induced ADP-ribosylation reaction.
Topics: Adenosine Diphosphate Ribose; Blood Platelets; Blood Proteins; Cytosol; Dithiothreitol; Humans; Kinetics; NAD; NADP; Nitric Oxide; Nitroprusside; Oxidation-Reduction; Poly(ADP-ribose) Polymerases | 1992 |
Glucose regulates the expression of Gi-proteins in cultured BC3H-1 myocytes.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Cell Line; Deoxyglucose; Glucose; GTP-Binding Proteins; Immune Sera; Immunoblotting; Kinetics; Mice; Molecular Sequence Data; Muscles; NAD; Oligopeptides; Pertussis Toxin; Virulence Factors, Bordetella | 1992 |
Ethanol enhances ADP-ribosylation of protein in rat hepatocytes.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Separation; DNA; Ethanol; Liver; Male; NAD; Proteins; Rats; Rats, Inbred Strains | 1992 |
Butylated hydroxytoluene prevents cumene hydroperoxide-induced Ca2+ release from liver mitochondria by inhibiting pyridine nucleotide hydrolysis.
Topics: Adenosine Diphosphate Ribose; Animals; Benzene Derivatives; Butylated Hydroxytoluene; Calcium; Hydrolysis; In Vitro Techniques; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Rats | 1992 |
Properties of 1-methyladenine receptors in starfish oocyte membranes: involvement of pertussis toxin-sensitive GTP-binding protein in the receptor-mediated signal transduction.
Topics: Adenine; Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cholic Acids; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Molecular Weight; NAD; Oocytes; Pertussis Toxin; Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Starfish; Virulence Factors, Bordetella | 1992 |
Posttranslational isoprenylation of rho protein is a prerequisite for its interaction with mastoparan and other amphiphilic agents.
Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Brain; Carbon Radioisotopes; Cloning, Molecular; Cytosol; Escherichia coli; GTP-Binding Proteins; Guanosine Triphosphate; Hemiterpenes; Intercellular Signaling Peptides and Proteins; Melitten; NAD; Oocytes; Organophosphorus Compounds; p-Methoxy-N-methylphenethylamine; Peptides; Protein Processing, Post-Translational; Recombinant Proteins; rhoA GTP-Binding Protein; Swine; Wasp Venoms; Xenopus laevis | 1992 |
ADP ribosylation of type II pulmonary epithelial cell G proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Botulinum Toxins; Cell Membrane; Cells, Cultured; Cholera Toxin; Cyclic AMP; Cytosol; Epithelium; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lung; Male; Membrane Proteins; NAD; Pertussis Toxin; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Signal Transduction; Virulence Factors, Bordetella | 1991 |
Nucleotide exchange and cGMP phosphodiesterase activation by pertussis toxin inactivated transducin.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Animals; Catalysis; Cattle; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hydrolysis; Kinetics; NAD; Nucleotides; Pertussis Toxin; Rod Cell Outer Segment; Structure-Activity Relationship; Transducin; Tryptophan; Virulence Factors, Bordetella | 1991 |
Pertussis toxin-sensitive G proteins are transported toward synaptic terminals by fast axonal transport.
Topics: Adenosine Diphosphate Ribose; Animals; Axonal Transport; Axons; Decapodiformes; GTP-Binding Proteins; In Vitro Techniques; Kinetics; Models, Neurological; NAD; Pertussis Toxin; Synapses; Temperature; Virulence Factors, Bordetella | 1991 |
The carboxyl terminus of the S1 subunit of pertussis toxin confers high affinity binding to transducin.
Topics: Adenosine Diphosphate Ribose; Binding Sites; Chromosome Deletion; Kinetics; Macromolecular Substances; NAD; Pertussis Toxin; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Transducin; Virulence Factors, Bordetella | 1991 |
Mono(ADP-ribosyl)ation of poly(ADP-ribose)polymerase by cholera toxin.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Autoradiography; Cattle; Cholera Toxin; Erythrocytes; Kinetics; NAD; Phosphorus Radioisotopes; Poly(ADP-ribose) Polymerases; Thymus Gland; Turkeys | 1991 |
Selective loss of pertussis toxin-sensitive G-proteins from the plasma membrane after antibody-induced internalization of T-cell surface molecules.
Topics: Adenosine Diphosphate Ribose; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; CD3 Complex; Cell Fractionation; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Cytosol; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; NAD; Pertussis Toxin; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Virulence Factors, Bordetella | 1991 |
ADP-ribosyl cyclase: an enzyme that cyclizes NAD+ into a calcium-mobilizing metabolite.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Aplysia; Calcium; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Electrophoresis, Polyacrylamide Gel; Kinetics; Magnetic Resonance Spectroscopy; N-Glycosyl Hydrolases; NAD; Niacinamide; Second Messenger Systems | 1991 |
Requirement of ADP-ribosylation for the pertussis toxin-induced alteration in electrophoretic mobility of G-proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Cell Line; Electrophoresis, Polyacrylamide Gel; Glioma; GTP-Binding Proteins; Hybrid Cells; Immunoblotting; Kinetics; Macromolecular Substances; NAD; Neuroblastoma; Niacinamide; Pertussis Toxin; Phosphorus Radioisotopes; Virulence Factors, Bordetella | 1991 |
Inhibition by cyclosporine A of the prooxidant-induced but not of the sodium-induced calcium release from rat kidney mitochondria.
Topics: Adenosine Diphosphate Ribose; Alloxan; Animals; Calcium; Cyclosporine; Female; Glutathione; Glutathione Disulfide; Hydrolysis; Kidney; Mitochondria; Mitochondria, Liver; NAD; Niacinamide; Oxidants; Peroxides; Rats; Rats, Inbred Strains; Sodium; tert-Butylhydroperoxide | 1991 |
Novel mechanism of intracellular calcium release in pituitary cells.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cell Line; Cell Membrane Permeability; Cyclic ADP-Ribose; Inositol 1,4,5-Trisphosphate; NAD; Pituitary Gland; Rats; Rats, Inbred Strains; Second Messenger Systems | 1991 |
Reduction of mono(ADP-ribosyl)ation of 20 kDa protein with maturation in rat testis: involvement of guanine nucleotides.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Aging; Animals; Cell Nucleus; Guanine Nucleotides; Male; Molecular Weight; NAD; Nuclear Proteins; Organ Specificity; Rats; Rats, Inbred Strains; Subcellular Fractions; Testis | 1991 |
Quantitation and purification of ADP-ribosylation factor.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; ADP-Ribosylation Factors; Animals; Brain; Cattle; Cell Membrane; Cholera Toxin; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Indicators and Reagents; Liver; Membrane Proteins; NAD; Phosphorus Radioisotopes; Rabbits; Radioisotope Dilution Technique; Sulfur Radioisotopes | 1991 |
ADP-ribosylation of G proteins with pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Chick Embryo; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Male; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Radioisotope Dilution Technique; Spermatozoa; Virulence Factors, Bordetella | 1991 |
Assay of G-protein beta gamma-subunit complex by catalytic support of ADP-ribosylation of Go alpha.
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cattle; Cell Membrane; Chromatography, Gel; Chromatography, Ion Exchange; GTP-Binding Proteins; Kinetics; Macromolecular Substances; NAD; Phosphorus Radioisotopes; Radioisotope Dilution Technique | 1991 |
Failure of [32P]ADP-ribosylation by pertussis toxin to determine Gi alpha content in membranes from various human tissues. Improved radioimmunological quantification using the 125I-labelled C-terminal decapeptide of retinal transducin.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Blood Platelets; Cell Line; Cell Membrane; GTP-Binding Proteins; Humans; Immune Sera; Immunoblotting; Iodine Radioisotopes; Macromolecular Substances; Molecular Sequence Data; NAD; Organ Specificity; Peptide Fragments; Pertussis Toxin; Phosphorus Radioisotopes; Radioimmunoassay; Radioisotope Dilution Technique; Retina; Sequence Homology, Nucleic Acid; Transducin; Virulence Factors, Bordetella | 1991 |
Inhibition of pertussis toxin catalyzed ADP-ribosylation of G-proteins by membrane depolarization in rat brain synaptoneurosomes.
Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Autoradiography; Brain Stem; Cell Membrane; GTP-Binding Proteins; Kinetics; Male; Membrane Potentials; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes; Virulence Factors, Bordetella | 1991 |
Phosphorylation of Gi protein by cyclic AMP-dependent protein kinase inhibits its dissociation into alpha-subunits and beta gamma-subunits by Mg2+ and GTP gamma S.
Topics: Adenosine Diphosphate Ribose; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Magnesium; NAD; Pertussis Toxin; Phosphorylation; Protein Conformation; Protein Kinases; Virulence Factors, Bordetella | 1991 |
A blue-light-activated GTP-binding protein in the plasma membranes of etiolated peas.
Topics: Adenosine Diphosphate Ribose; Cell Membrane; Cholera Toxin; Cross Reactions; Darkness; Fabaceae; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Light; Molecular Weight; NAD; Pertussis Toxin; Plants, Medicinal; Virulence Factors, Bordetella | 1991 |
Pseudomonas exotoxin A prevents beta-adrenoceptor-induced upregulation of Gi protein alpha-subunits and adenylyl cyclase desensitization in rat heart muscle cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; ADP Ribose Transferases; Adrenergic beta-Antagonists; Animals; Bacterial Toxins; Cells, Cultured; Colforsin; Exotoxins; GTP-Binding Proteins; Heart; Isoproterenol; Kinetics; Macromolecular Substances; Muscle, Smooth; Myocardium; NAD; Norepinephrine; Propanolamines; Pseudomonas aeruginosa Exotoxin A; Rats; Receptors, Adrenergic, beta; Virulence Factors | 1990 |
ATP-dependent and NAD-dependent modification of glutamine synthetase from Rhodospirillum rubrum in vitro.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Immune Sera; Immunoblotting; Kinetics; Malates; Molecular Sequence Data; NAD; Peptide Fragments; Phosphorus Radioisotopes; Rhodospirillum rubrum | 1990 |
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
Topics: Adenosine Diphosphate Ribose; Affinity Labels; Aspartic Acid; Base Sequence; Binding Sites; Diphtheria Toxin; Glutamates; Glutamic Acid; Glutamine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Serine; Substrate Specificity | 1990 |
ADP-ribosylation in Clostridium difficile toxin-treated cells is not related to cytopathogenicity of toxin B.
Topics: Adenosine Diphosphate Ribose; Animals; Bacterial Proteins; Bacterial Toxins; Carbon Radioisotopes; Cell Line; Clostridioides difficile; Cytotoxins; Humans; Molecular Weight; NAD | 1991 |
DNA strand breaks and DNA repair response in lymphocytes after chronic in vivo exposure to very low doses of ionizing radiation in mice.
Topics: Adenine Phosphoribosyltransferase; Adenosine Diphosphate Ribose; Animals; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Mice; Mice, Inbred C57BL; NAD; Spleen; T-Lymphocytes; Whole-Body Irradiation | 1991 |
Meta-iodobenzylguanidine (MIBG), a novel high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation).
Topics: 3-Iodobenzylguanidine; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Cell Line; Cholera Toxin; Erythrocyte Membrane; Iodobenzenes; Kinetics; Membrane Proteins; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Turkeys; Tyramine | 1990 |
Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Membrane; DNA; GTP-Binding Proteins; Hydroxylamine; Hydroxylamines; Macromolecular Substances; Methionine; Molecular Sequence Data; Mutation; Myristic Acid; Myristic Acids; NAD; Pertussis Toxin; Protein Processing, Post-Translational; Transfection; Virulence Factors, Bordetella | 1990 |
Isoproterenol stimulates shift of G proteins from plasma membrane to pinocytotic vesicles in rat adipocytes: a possible means of signal dissemination.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Azides; Cell Fractionation; Cell Membrane; Cholera Toxin; GTP-Binding Proteins; Isoproterenol; Male; NAD; Organelles; Pinocytosis; Rats; Rats, Inbred Strains; Signal Transduction; Sodium Azide; Sodium Fluoride; Virulence Factors, Bordetella | 1990 |
Effect of GTP gamma S on insulin binding and tyrosine phosphorylation in liver membranes and L6 muscle cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Cell Membrane Permeability; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Insulin; Kinetics; Liver; Male; Muscles; NAD; Phosphorylation; Rats; Rats, Inbred Strains; Receptor, Insulin; Thionucleotides; Tyrosine | 1990 |
Two distinct light regulated G-proteins in octopus photoreceptors.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cattle; Cell Membrane; Cholera Toxin; Darkness; GTP-Binding Proteins; Light; Molecular Weight; NAD; Octopodiformes; Pertussis Toxin; Photoreceptor Cells; Rod Cell Outer Segment; Virulence Factors, Bordetella | 1990 |
Pertussis toxin-catalyzed ADP-ribosylation of a G protein in mouse oocytes, eggs, and preimplantation embryos: developmental changes and possible functional roles.
Topics: Adenosine Diphosphate Ribose; Animals; Blastocyst; Cell Division; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Female; GTP-Binding Proteins; Kinetics; Male; Methionine; Mice; Mice, Inbred Strains; Molecular Weight; NAD; Oocytes; Ovum; Pertussis Toxin; Sulfur Radioisotopes; Transcription, Genetic; Virulence Factors, Bordetella; Zona Pellucida | 1990 |
2-Azido-[32P]NAD+, a photoactivatable probe for G-protein structure: evidence for holotransducin oligomers in which the ADP-ribosylated carboxyl terminus of alpha interacts with both alpha and gamma subunits.
Topics: Adenosine Diphosphate Ribose; Affinity Labels; Animals; Azides; GTP-Binding Proteins; Macromolecular Substances; Models, Structural; Molecular Structure; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Photolysis; Retina; Transducin; Virulence Factors, Bordetella | 1990 |
Chronic exposure of rat glioma C6 cells to cholera toxin induces loss of the alpha-subunit of the stimulatory guanine nucleotide-binding protein (Gs).
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cholera Toxin; Down-Regulation; Glioma; GTP-Binding Proteins; Immunoblotting; NAD; Pertussis Toxin; Rats; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Identification of ADPR-transferase activity in the rat tapeworm, Hymenolepis diminuta.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Benzamides; Cell Nucleus; Hymenolepis; Kinetics; Male; NAD; Nuclear Proteins; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats | 1990 |
Proximal tubular epithelial cells possess a novel 42-kilodalton guanine nucleotide-binding regulatory protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Aluminum; Aluminum Compounds; Animals; Cell Membrane; Cholera Toxin; Colforsin; Epithelium; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kidney Tubules, Proximal; Kinetics; Male; Microvilli; Molecular Weight; NAD; Parathyroid Hormone; Pertussis Toxin; Rabbits; Virulence Factors, Bordetella | 1990 |
Muscarinic cholinergic stimulation of inositol phosphate production in cultured embryonic chick atrial cells. Evidence for a role of two guanine-nucleotide-binding proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Atropine; Cells, Cultured; Chick Embryo; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; Inositol Phosphates; Kinetics; Myocardium; NAD; Pertussis Toxin; Receptors, Muscarinic; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
Adaptive changes in NAD+ metabolism in ultraviolet light-irradiated murine lymphoma cells.
Topics: Adaptation, Physiological; Adenosine Diphosphate Ribose; Animals; Benzamides; Cell Count; DNA Damage; Lymphoma; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured; Ultraviolet Rays | 1990 |
Analysis for protein modifications and nonprotein cofactors.
Topics: Adenosine Diphosphate Ribose; Animals; Cross-Linking Reagents; Glycolipids; Glycosylphosphatidylinositols; Methods; NAD; Phosphatidylinositols; Phosphorylation; Protein Processing, Post-Translational; Proteins | 1990 |
Inhibition of pro-oxidant-induced mitochondrial pyridine nucleotide hydrolysis and calcium release by 4-hydroxynonenal.
Topics: Adenosine Diphosphate Ribose; Aldehydes; Alloxan; Animals; Calcium; Female; Hydrolysis; Intracellular Fluid; Mitochondria, Liver; NAD; Niacinamide; Rats; Rats, Inbred Strains | 1990 |
De-ADP-ribosylation actin by Clostridium perfringens iota-toxin and Clostridium botulinum C2 toxin.
Topics: Actins; Adenosine Diphosphate Ribose; Adenosine Triphosphatases; ADP Ribose Transferases; Animals; Bacterial Toxins; Botulinum Toxins; Cells, Cultured; Edetic Acid; Muscles; NAD; Rabbits | 1990 |
Cyclic AMP regulation of Gs protein. Thyrotropin and forskolin increase the quantity of stimulatory guanine nucleotide-binding proteins in cultured thyroid follicles.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Immunoblotting; NAD; Swine; Thyroid Gland; Thyrotropin | 1990 |
Effects of beta-adrenergic receptor activation, cholera toxin and forskolin on human natural killer cell function.
Topics: Adenosine Diphosphate Ribose; Calcimycin; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Cytotoxicity, Immunologic; Epinephrine; Humans; In Vitro Techniques; Isoproterenol; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Membrane Proteins; NAD; Phosphorus Radioisotopes; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1990 |
Kinetic determination of the effects of ADP-ribosylation on the interaction of eukaryotic elongation factor 2 with ribosomes.
Topics: Adenosine Diphosphate Ribose; Animals; Carcinoma, Ehrlich Tumor; Diphtheria Toxin; Guanosine Triphosphate; Kinetics; Mice; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Ribosomes; Ricin | 1990 |
A specific beta gamma-subunit of transducin stimulates ADP-ribosylation of the alpha-subunit by pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Kinetics; Macromolecular Substances; NAD; Pertussis Toxin; Rod Cell Outer Segment; Transducin; Virulence Factors, Bordetella | 1990 |
Modification of the reactivity of three amino-acid residues in elongation factor 2 during its binding to ribosomes and translocation.
Topics: Adenosine Diphosphate Ribose; Animals; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Liver; Mutation; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Binding; Rats; Ribosomes; Trypsin | 1990 |
Agonist-induced ADP-ribosylation of a cytosolic protein in human platelets.
Topics: Adenosine Diphosphate Ribose; Alkaloids; Blood Platelets; Blood Proteins; Cell Membrane Permeability; Cholera Toxin; Cytosol; Humans; In Vitro Techniques; Kinetics; Molecular Weight; NAD; Phorbol 12,13-Dibutyrate; Staurosporine; Thrombin | 1990 |
Serotonin receptor-mediated activation of adenylate cyclase in the neuroblastoma NCB.20: a novel 5-hydroxytryptamine receptor.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cholera Toxin; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; NAD; Neuroblastoma; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Thionucleotides; Tumor Cells, Cultured | 1990 |
Agonist-induced down-regulation of muscarinic cholinergic and alpha 2-adrenergic receptors after inactivation of Ni by pertussis toxin.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; ATPase Inhibitory Protein; Carbachol; Cell Line; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epinephrine; Glioma; Guanylyl Imidodiphosphate; Molecular Weight; NAD; Neuroblastoma; Pertussis Toxin; Proteins; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine; Virulence Factors, Bordetella; Yohimbine | 1986 |
Reconstitution of cyc- S49 membranes by in vitro translated Gs alpha. Membrane anchorage and functional implications.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Isoproterenol; Lymphoma; Mice; Molecular Weight; Mutation; NAD; Osmolar Concentration; Protein Biosynthesis; RNA, Messenger; Thionucleotides; Tumor Cells, Cultured | 1989 |
Heterologous desensitization of the liver adenylyl cyclase: analysis of the role of G-proteins.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Chickens; Glucagon; GTP-Binding Proteins; Kinetics; Liver; Macromolecular Substances; NAD; Pertussis Toxin; Phosphorylation; Protein Kinases; Virulence Factors, Bordetella | 1989 |
Chronic exposure of NG 108-15 cells to opiate agonists does not alter the amount of the guanine nucleotide-binding proteins Gi and Go.
Topics: Adenosine Diphosphate Ribose; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; GTP-Binding Proteins; Hybrid Cells; Immunoblotting; Morphine; NAD; Neuroblastoma; Pertussis Toxin; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Two distinct Gi-proteins mediate formyl peptide receptor signal transduction in human leukemia (HL-60) cells.
Topics: Adenosine Diphosphate Ribose; Cell Line; Cell Membrane; Cholera Toxin; GTP-Binding Proteins; Humans; Leukemia, Promyelocytic, Acute; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; NAD; Peptide Mapping; Receptors, Formyl Peptide; Receptors, Immunologic; Signal Transduction; Tumor Cells, Cultured | 1989 |
Utilization of 2'-deoxynad for ADP-ribose transfer reactions.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Diphtheria Toxin; Humans; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 1989 |
Foetal calf serum enhances cholera toxin-catalysed ADP-ribosylation of the pertussis toxin-sensitive guanine nucleotide binding protein, Gi2, in rat glioma C6BU1 cells.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation Factors; Animals; Cholera Toxin; Gene Expression Regulation, Neoplastic; Glioma; Growth Substances; GTP Phosphohydrolases; GTP-Binding Proteins; Molecular Weight; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Pertussis toxin induces structural changes in G alpha proteins independently of ADP-ribosylation.
Topics: Adenine Nucleotides; Adenosine Diphosphate Ribose; Animals; Blotting, Western; Brain; Cattle; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; In Vitro Techniques; Membrane Proteins; NAD; Niacinamide; Pentosyltransferases; Pertussis Toxin; Virulence Factors, Bordetella | 1989 |
Differentiation of 3T3-L1 pre-adipocytes induced by inhibitors of poly(ADP-ribose) polymerase and by related noninhibitory acids.
Topics: Adenosine Diphosphate Ribose; Adipose Tissue; ADP Ribose Transferases; Animals; Benzamides; Benzoates; Benzoic Acid; Cell Differentiation; Cell Line; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation; Glycerolphosphate Dehydrogenase; High Mobility Group Proteins; Insulin; Mice; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 1989 |
Elevated levels of the guanine nucleotide binding protein, Go, are associated with differentiation of neuroblastoma x glioma hybrid cells.
Topics: Adenosine Diphosphate Ribose; Alprostadil; Blotting, Western; Bucladesine; Cell Differentiation; Cell Membrane; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Glioma; GTP-Binding Proteins; Hybrid Cells; Molecular Weight; NAD; Neuroblastoma; Pertussis Toxin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
A specific, low Km ADP-ribose pyrophosphatase from rat liver.
Topics: Adenosine Diphosphate Glucose; Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Dinucleoside Phosphates; Hydrogen-Ion Concentration; Liver; Magnesium; Manganese; NAD; Pyrophosphatases; Rats; Substrate Specificity | 1989 |
Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Benzamides; Bromodeoxyuridine; Cattle; NAD; NAD+ Nucleosidase; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors | 1989 |
Inhibition of prolyl hydroxylase by poly(ADP-ribose) and phosphoribosyl-AMP. Possible role of ADP-ribosylation in intracellular prolyl hydroxylase regulation.
Topics: Adenosine; Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Cell Nucleus; Chick Embryo; Enzyme Activation; Fibroblasts; Hydroxylation; Lactates; Lactic Acid; Liver; Mixed Function Oxygenases; NAD; Nucleoside Diphosphate Sugars; Phosphodiesterase I; Phosphoric Diester Hydrolases; Poly Adenosine Diphosphate Ribose; Procollagen; Procollagen-Proline Dioxygenase; Rabbits; Rats | 1989 |
Cholera toxin ADP-ribosylates the receptor-coupled form of pertussis toxin-sensitive G-proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Cholera Toxin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; GTP Phosphohydrolases; GTP-Binding Proteins; Hybrid Cells; NAD; Neuroblastoma; Pertussis Toxin; Receptors, Opioid; Virulence Factors, Bordetella | 1989 |
ADP-ribosylation of thylakoid membrane polypeptides by cholera toxin is correlated with inhibition of thylakoid GTPase activity and protein phosphorylation.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Chloroplasts; Cholera Toxin; Fabaceae; GTP Phosphohydrolases; GTP-Binding Proteins; Light; Membrane Proteins; NAD; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotransferases; Plant Proteins; Plants, Medicinal | 1989 |
Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Insulin Resistance; Liver; Male; NAD; Obesity; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Rats, Zucker; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Virulence Factors, Bordetella | 1989 |
Estimating the amounts of ADP-ribosylatable active elongation factor-2 in mammalian cell-free extracts.
Topics: Adenosine Diphosphate Ribose; Animals; Carbon Radioisotopes; Diphtheria Toxin; HeLa Cells; Humans; Kinetics; Liver; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Radioisotope Dilution Technique; Rats | 1989 |
Alkylation of cysteine 41, but not cysteine 200, decreases the ADP-ribosyltransferase activity of the S1 subunit of pertussis toxin.
Topics: Acylation; Adenosine Diphosphate Ribose; Alkylating Agents; Binding Sites; Cysteine; Macromolecular Substances; NAD; Pentosyltransferases; Pertussis Toxin; Structure-Activity Relationship; Virulence Factors, Bordetella | 1989 |
Widespread occurrence in animal tissues of an enzyme catalyzing the conversion of NAD+ into a cyclic metabolite with intracellular Ca2+-mobilizing activity.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Chromatography, High Pressure Liquid; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; NAD; Ovum; Rabbits; Sea Urchins; Substrate Specificity | 1989 |
[Inhibition of the transport of citrate during ADP-ribosylation of inner membrane proteins of the mitochondria].
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport; Citrates; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Intracellular Membranes; Male; Membrane Proteins; Mitochondria, Liver; NAD; Protein Processing, Post-Translational; Rats; Submitochondrial Particles | 1989 |
Role of a guanine nucleotide-binding protein in alpha 1-adrenergic receptor-mediated Ca2+ mobilization in DDT1 MF-2 cells.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cell Line; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Triphosphate; Molecular Weight; Muscle, Smooth; NAD; Pertussis Toxin; Phenylephrine; Receptors, Adrenergic, alpha; Saponins; Virulence Factors, Bordetella | 1987 |
Forskolin-resistant Y1 mutants harbor defects associated with the guanyl nucleotide-binding regulatory protein, Gs.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; Colforsin; Drug Resistance; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Manganese; Mice; Mutation; NAD; Phenotype; Sodium Fluoride | 1987 |
Cholera toxin affects nuclear ADP-ribosylation in GH1 cells.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bucladesine; Cell Line; Cell Nucleus; Cholera Toxin; Chromatin; Cyclic AMP; Histones; Micrococcal Nuclease; Molecular Weight; NAD; Nuclear Proteins; Pentosyltransferases; Pituitary Gland; Poly(ADP-ribose) Polymerases | 1988 |
Mono(ADP-ribosylation) in rat liver mitochondria.
Topics: Adenosine Diphosphate Ribose; Animals; Hydroxylamine; Hydroxylamines; Intracellular Membranes; Kinetics; Mitochondria, Liver; NAD; NAD+ Nucleosidase; Proteins; Rats; Submitochondrial Particles | 1988 |
ADP-ribosylation of membrane proteins by bacterial toxins in the presence of NAD glycohydrolase.
Topics: Adenosine Diphosphate Ribose; Animals; Brain Chemistry; Cattle; Cholera Toxin; Columbidae; Drug Synergism; Erythrocyte Membrane; GTP-Binding Proteins; Isoniazid; Membrane Proteins; Mice; NAD; NAD+ Nucleosidase; Pertussis Toxin; Swine; Virulence Factors, Bordetella | 1988 |
ADP-ribosylation by cholera toxin of membranes derived from brain modifies the interaction of adenylate cyclase with guanine nucleotides and NaF.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Brain; Cattle; Caudate Nucleus; Cell Membrane; Cholera Toxin; Coenzymes; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoniazid; Kinetics; NAD; NAD+ Nucleosidase; Sodium Fluoride | 1988 |
Cholera toxin potentiates IgE-coupled inositol phospholipid hydrolysis and mediator secretion by RBL-2H3 cells.
Topics: Acetylglucosaminidase; Adenosine Diphosphate Ribose; Cell Line; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Hydrolysis; Immunoglobulin E; NAD; Phosphatidylinositols; Receptors, Fc; Serotonin | 1988 |
Interaction of beta-adrenergic receptors with the inhibitory guanine nucleotide-binding protein of adenylate cyclase in membranes prepared from cyc- S49 lymphoma cells.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; GTP-Binding Proteins; Isoproterenol; Lymphoma; Membranes; Molecular Weight; NAD; Pertussis Toxin; Pindolol; Receptors, Adrenergic, beta; Virulence Factors, Bordetella | 1988 |
Agonist and antagonist binding to alpha 2-adrenergic receptors in purified membranes from human platelets. Implications of receptor-inhibitory nucleotide-binding protein stoichiometry.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Platelets; Brimonidine Tartrate; Clonidine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; NAD; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Involvement of Gi in the inhibition of adenylate cyclase by cannabimimetic drugs.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cannabinoids; Carbachol; Cells, Cultured; Cyclic AMP; Dronabinol; Glioma; GTP-Binding Proteins; Hybrid Cells; Lymphoma; Manganese; Membrane Proteins; Morphine; NAD; Neuroblastoma; Pertussis Toxin; Rats; Secretin; Somatostatin; Virulence Factors, Bordetella | 1986 |
A pertussis toxin substrate regulates alpha 1-adrenergic dependent phosphatidylinositol hydrolysis in cultured rat myocytes.
Topics: Adenosine Diphosphate Ribose; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Heart; Hydrolysis; Inositol Phosphates; Kinetics; Myocardium; NAD; Norepinephrine; Pertussis Toxin; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella | 1987 |
Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activity.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; NAD; Oocytes; Sea Urchins | 1989 |
Estrogen effects on modifications of chromatin proteins in the rat uterus.
Topics: Acetylation; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Chromatin; Estradiol; Female; High Mobility Group Proteins; Histones; NAD; Phosphorylation; Rats; Reference Values; Uterus | 1989 |
Mechanisms of poly(ADP-ribose) polymerase catalysis; mono-ADP-ribosylation of poly(ADP-ribose) polymerase at nanomolar concentrations of NAD.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Cattle; Hydroxylamine; Hydroxylamines; Kinetics; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Poly(ADP-ribose) Polymerases | 1986 |
ADP-ribosylation in cultured cells treated with Clostridium difficile toxin B.
Topics: Adenosine Diphosphate Ribose; Bacterial Proteins; Bacterial Toxins; Carbon Radioisotopes; Cells, Cultured; Humans; NAD; Niacinamide | 1986 |
NAD+-mediated stimulation of adenylate cyclase in cardiac membranes.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Arginine; Cell Membrane; Colforsin; Enzyme Activation; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Manganese; Myocardium; NAD; NADP; Niacinamide; Rabbits; Sodium Fluoride | 1987 |
ADP-ribosylation of Ca2+-dependent ATPase in vitro suppresses the enzyme activity.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium-Transporting ATPases; In Vitro Techniques; Kinetics; NAD; Pentosyltransferases; Polylysine; Rabbits; Sarcoplasmic Reticulum; Structure-Activity Relationship | 1987 |
Tumor necrosis factor-mediated cytotoxicity involves ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Benzamides; Cell Line; Cell Survival; Fibroblasts; Humans; Intracellular Fluid; Kinetics; Mice; NAD; Niacinamide; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1988 |
Decrease of clonidine binding affinity to alpha 2-adrenoceptor by ADP-ribosylation of 41,000-dalton proteins in rat cerebral cortical membranes by islet-activating protein.
Topics: Adenosine Diphosphate Ribose; Animals; Bacterial Toxins; Binding, Competitive; Cell Membrane; Cerebral Cortex; Clonidine; GTP-Binding Proteins; Guanosine Triphosphate; Male; Membrane Proteins; NAD; Nucleoside Diphosphate Sugars; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine | 1985 |
NAD and the synthesis of (ADP-ribose)n in a human cell strain (46BR) hypersensitive to the lethal effects of 3-aminobenzamide.
Topics: Adenosine Diphosphate Ribose; Benzamides; Cell Line; Cell Survival; Humans; Immunologic Deficiency Syndromes; In Vitro Techniques; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases | 1985 |
Prevention of the agonist binding to gamma-aminobutyric acid B receptors by guanine nucleotides and islet-activating protein, pertussis toxin, in bovine cerebral cortex. Possible coupling of the toxin-sensitive GTP-binding proteins to receptors.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cerebral Cortex; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; NAD; Pertussis Toxin; Receptors, GABA-A; Virulence Factors, Bordetella | 1985 |
1-N6-Etheno-ADP-ribosylation of elongation factor-2 by diphtheria toxin.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Chromatography; Diphtheria Toxin; Female; Humans; Kinetics; NAD; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Fragments; Phosphoric Diester Hydrolases; Placenta; Pregnancy; Spectrometry, Fluorescence | 1985 |
Modification of nuclear matrix proteins by ADP-ribosylation. Association of nuclear ADP-ribosyltransferase with the nuclear matrix.
Topics: Adenosine Diphosphate Ribose; Cell Nucleus; Chromatography; HeLa Cells; Humans; NAD; Nucleoproteins; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases | 1985 |
A gel-electrophoretic analysis of protein ADP-ribosylation in polyoma virus-transformed and non-transformed BHK-21/C13 fibroblasts.
Topics: Adenosine Diphosphate Ribose; Animals; Benzamides; Cell Line; Cell Membrane Permeability; Cell Transformation, Viral; Cricetinae; Electrophoresis, Polyacrylamide Gel; Fibroblasts; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Polyomavirus; Proteins; Solubility | 1986 |
Dexamethasone effects on beta-adrenergic receptors and adenylate cyclase regulatory proteins Gs and Gi in ROS 17/2.8 cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Cyclic AMP; Cycloheximide; Dexamethasone; Dihydroalprenolol; Enzyme Activation; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Molecular Weight; NAD; Osteosarcoma; Rats; Receptors, Adrenergic, beta | 1986 |
Reversible inactivation of ribonucleases by ADPribosylation.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cell Nucleus; Hydrolysis; Kinetics; Male; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Ribonuclease, Pancreatic; Ribonucleases; Semen; Spectrophotometry, Ultraviolet | 1986 |
Increased protein ADPribosylation in HeLa cells exposed to the anti-cancer drug methotrexate.
Topics: Adenosine Diphosphate Ribose; Cell Nucleus; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Kinetics; Methotrexate; Molecular Weight; NAD; Neoplasm Proteins; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases | 1986 |
NAD+ glycohydrolase of the plasma membrane prepared from glial and neuronal cells.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Binding, Competitive; Brain; Cell Membrane; Cells, Cultured; Chick Embryo; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; NAD; NAD+ Nucleosidase; Neuroglia; Neurons; Niacinamide; Rats | 1986 |
A surface NAD-glycohydrolase of human platelets may influence their aggregation.
Topics: Adenosine; Adenosine Diphosphate Ribose; Blood Platelets; Cell Membrane; Humans; NAD; NAD+ Nucleosidase; Niacinamide; Platelet Aggregation; Thrombin | 1986 |
ADPribosylation of nuclear proteins labeled with [3H]adenosine: changes during the HeLa cycle.
Topics: Adenosine; Adenosine Diphosphate Ribose; Benzamides; Cell Cycle; Cell Nucleus; Chromosomal Proteins, Non-Histone; HeLa Cells; Histones; Humans; Interphase; Lamins; Metaphase; NAD; Nucleoproteins; Phosphoric Diester Hydrolases | 1987 |
Evidence of a yeast proteinase specific for elongation factor 2.
Topics: Adenosine Diphosphate Ribose; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Hydrolases; Saccharomyces | 1988 |
Equilibrium of 5,6-hydration of NADH and mechanism of ATP-dependent dehydration.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; NAD; Saccharomyces cerevisiae; Stereoisomerism; Substrate Specificity; Water | 1988 |
Reversible regulation of the nitrogenase iron protein from Rhodospirillum rubrum by ADP-ribosylation in vitro.
Topics: Adenosine Diphosphate Ribose; Ammonia; Chromatography, High Pressure Liquid; NAD; Nitrogenase; Nucleoside Diphosphate Sugars; Oxidoreductases; Rhodospirillum rubrum; Time Factors | 1986 |
Alpha-subunits of Ns are released from the plasma membrane following cholera toxin activation.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cell Membrane; Cholera Toxin; GTP-Binding Proteins; In Vitro Techniques; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Virulence Factors, Bordetella | 1986 |
Pertussis toxin alters the growth characteristics of Swiss 3T3 cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Cycle; Cell Line; Cholera Toxin; GTP-Binding Proteins; Mice; NAD; Pertussis Toxin; Virulence Factors, Bordetella | 1986 |
Catalytic activities of synthetic octadeoxyribonucleotides as coenzymes of poly(ADP-ribose) polymerase and the identification of a new enzyme inhibitory site.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Binding Sites; Catalysis; Coenzymes; DNA; Histones; Kinetics; NAD; Oligodeoxyribonucleotides; Pentosyltransferases; Poly(ADP-ribose) Polymerases | 1987 |
Guanine nucleotide regulation of the pertussis and cholera toxin substrates of rat glioma C6 BU1 cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cholera Toxin; Glioma; GTP-Binding Proteins; Guanine Nucleotides; Molecular Weight; NAD; Pertussis Toxin; Rats; Virulence Factors, Bordetella | 1987 |
Type II heat-labile enterotoxin of Escherichia coli activates adenylate cyclase in human fibroblasts by ADP ribosylation.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alprostadil; Bacterial Toxins; Carbachol; Cholera Toxin; Dithiothreitol; Enterotoxins; Enzyme Activation; Escherichia coli Proteins; Fibroblasts; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoproterenol; NAD; Trypsin | 1987 |
Reaction mechanism for automodification of poly(ADP-ribose) synthetase.
Topics: Adenosine Diphosphate Ribose; Magnesium; NAD; Poly(ADP-ribose) Polymerases | 1987 |
Eukaryotic mono(ADP-ribosyl)transferase that ADP-ribosylates GTP-binding regulatory Gi protein.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Botulinum Toxins; Cysteine; Erythrocytes; GTP-Binding Proteins; Humans; Hydroxylamine; Hydroxylamines; Kinetics; Molecular Weight; NAD | 1988 |
Endogenous inhibitor of the ADP-ribosylation of (a) G-protein(s) as catalyzed by pertussis toxin is present in rat liver.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Kinetics; Liver; Male; NAD; Pertussis Toxin; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1988 |
Purification and properties of the cytosolic substrate for botulinum ADP-ribosyltransferase. Identification as an Mr 22,000 guanine nucleotide-binding protein.
Topics: Adenosine Diphosphate Ribose; Adrenal Glands; Animals; Binding, Competitive; Cattle; Chromatography; Chromatography, High Pressure Liquid; Clostridium botulinum; Cytosol; Electrophoresis, Polyacrylamide Gel; Fractional Precipitation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Male; NAD; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains; Thionucleotides; Tissue Distribution | 1988 |
Selective probing of ADP-ribosylation reactions with oxidized 2'-deoxy-nicotinamide adenine dinucleotide.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Cattle; Erythrocytes; Kinetics; NAD; Oxidation-Reduction; Poly(ADP-ribose) Polymerases | 1988 |
Different types of ADP-ribose protein bonds formed by botulinum C2 toxin, botulinum ADP-ribosyltransferase C3 and pertussis toxin.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Blood Platelets; Blood Proteins; Botulinum Toxins; Cell Membrane; Cytosol; Ethylmaleimide; GTP-Binding Proteins; Humans; NAD; Pertussis Toxin; Virulence Factors, Bordetella | 1988 |
Purification and properties of dinitrogenase reductase ADP-ribosyltransferase from the photosynthetic bacterium Rhodospirillum rubrum.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Dinitrogenase Reductase; Ferredoxins; Glycoside Hydrolases; Hydrogen-Ion Concentration; Molecular Weight; N-Glycosyl Hydrolases; NAD; Rhodospirillum rubrum; Sodium Chloride | 1988 |
Prolactin differentially affects bacterial toxin-induced ADP-ribosylation of Nb2 lymphoma cell membrane proteins.
Topics: Adenosine Diphosphate Ribose; Bacterial Toxins; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Kinetics; Lymphoma; Membrane Proteins; Molecular Weight; NAD; Pertussis Toxin; Prolactin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
Fluorescent labeling of signal-transducing G-proteins. Pertussis toxin-catalyzed etheno-ADP ribosylation of transducin.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Fluorescent Dyes; GTP-Binding Proteins; Kinetics; NAD; Pertussis Toxin; Photoreceptor Cells; Rod Cell Outer Segment; Signal Transduction; Spectrometry, Fluorescence; Transducin; Virulence Factors, Bordetella | 1988 |
Endogenous ADP-ribosylation in human platelets.
Topics: Adenosine Diphosphate Ribose; Blood Platelets; Cholera Toxin; Chromatography, High Pressure Liquid; Cytosol; Dithiothreitol; Enzyme Activation; Humans; Kinetics; Magnesium; NAD; Pertussis Toxin; Phosphates; Poly(ADP-ribose) Polymerases; Potassium; Potassium Compounds; Serum Albumin; Virulence Factors, Bordetella | 1988 |
Direct observation of the NAD glycohydrolase reaction in human erythrocytes using NMR spectroscopy.
Topics: Adenosine Diphosphate Ribose; Erythrocytes; Humans; Kinetics; Magnetic Resonance Spectroscopy; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Niacinamide | 1985 |
The relationship of nicotinamide adenine dinucleotide to the chondrogenic differentiation of limb mesenchymal cells.
Topics: Adenosine Diphosphate Ribose; Animals; Benzamides; Cartilage; Cell Differentiation; Cell Division; Cells, Cultured; Chick Embryo; Extremities; Mesoderm; NAD; Niacin; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Proteoglycans; Sulfates | 1985 |
[ADP-ribosylation of nuclear proteins in the rat brain].
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cell Nucleus; DNA; DNA, Superhelical; Electrophoresis, Polyacrylamide Gel; NAD; Nuclear Proteins; Nucleic Acid Conformation; Rats | 1988 |
Labeling methods for the study of poly- and mono(ADP-ribose) metabolism in cultured cells.
Topics: Adenosine Diphosphate Ribose; Animals; Boronic Acids; Cells, Cultured; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Sepharose; Tritium | 1988 |
ADP-ribosyl proteins formed by pertussis toxin are specifically cleaved by mercury ions.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cysteine; Histones; Hydrolysis; Mercury; Mitochondria, Heart; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptides; Pertussis Toxin; Proteins; Submitochondrial Particles; Transducin; Virulence Factors, Bordetella | 1988 |
Pertussis toxin treatment attenuates some effects of insulin in BC3H-1 murine myocytes.
Topics: Adenosine Diphosphate Ribose; Animals; Chromatography, Thin Layer; Diglycerides; Dose-Response Relationship, Drug; Glucosamine; Inositol; Insulin; Mice; Molecular Weight; Muscles; Myristates; NAD; Pertussis Toxin; Virulence Factors, Bordetella | 1988 |
GTP-dependent ADP-ribosylation of a 22 kDa protein in the endoplasmic reticulum membrane.
Topics: Adenosine Diphosphate Ribose; Animals; Biological Transport; Cholera Toxin; Dogs; Endopeptidases; Guanosine Triphosphate; Guinea Pigs; Intracellular Membranes; Membrane Proteins; Microsomes; Microsomes, Liver; NAD; Pancreas; Pertussis Toxin; Protein Biosynthesis; Protein Precursors; Protein Processing, Post-Translational; Serine Endopeptidases; Virulence Factors, Bordetella | 1987 |
Slow DNA rejoining in ultraviolet-irradiated human diploid fibroblasts treated with the mitogens trypsin and insulin.
Topics: Adenosine Diphosphate Ribose; Cell Survival; Deoxyribonucleotides; DNA; DNA Damage; DNA Repair; Fibroblasts; Humans; Insulin; NAD; Ribonucleotides; Trypsin; Ultraviolet Rays | 1987 |
Use of liposome encapsulation in a combined single-liquid reagent for homogeneous enzyme immunoassay.
Topics: Adenosine Diphosphate Ribose; Antibodies; Antigen-Antibody Reactions; Glucosephosphate Dehydrogenase; Humans; Immunoenzyme Techniques; Indicators and Reagents; Liposomes; NAD; Quality Control; Theophylline | 1987 |
Stimulation of mono (ADP-ribosyl)ation by reduced extracellular calcium levels in human fibroblasts.
Topics: Adenosine Diphosphate Ribose; Calcium; Cells, Cultured; Extracellular Space; Fibroblasts; Homeostasis; Humans; Male; NAD; Skin; Stimulation, Chemical | 1988 |
Factors influencing ADP-ribosylation differences between chromosomal proteins of interphase and metaphase HeLa cells.
Topics: Adenosine Diphosphate Ribose; Animals; Benzimidazoles; Cell Line; Cell Nucleus; Chromatin; Chromosomal Proteins, Non-Histone; Chromosomes; Cycloheximide; Deoxyadenosines; DNA Damage; HeLa Cells; Humans; Hydroxyurea; Interphase; Isoelectric Point; Metaphase; Molecular Weight; NAD; Nocodazole; Rats; Thymidine | 1987 |
Enhancement of parathyroid hormone-responsive renal cortical adenylate cyclase activity by a cytosol protein activator from rat reticulocytes.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Arginine Vasopressin; Cytosol; Dogs; Drug Synergism; Female; Glucagon; Isoproterenol; Kidney Cortex; NAD; Parathyroid Hormone; Rats; Reticulocytes | 1986 |
ADP-ribosylation of nonmuscle actin with component I of C2 toxin.
Topics: Actins; Adenosine Diphosphate Ribose; Animals; Botulinum Toxins; Brain Chemistry; Cell Line; Chickens; Clostridium botulinum; Intestines; Kidney; Macaca fascicularis; Molecular Weight; Muscles; NAD; Nucleoside Diphosphate Sugars; Rabbits | 1986 |
Botulinum C2 toxin ADP-ribosylates actin and disorganizes the microfilament network in intact cells.
Topics: Actin Cytoskeleton; Actins; Adenosine Diphosphate Ribose; Animals; Botulinum Toxins; Chick Embryo; Cytoskeleton; Kinetics; NAD; Phosphates; Proteins | 1987 |
Kinetics of coenzyme binding to liver alcohol dehydrogenase in the pH range 10-12.
Topics: Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Animals; Horses; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; Protein Binding; Water; Zinc | 1987 |
Classical Raman spectroscopic studies of NADH and NAD+ bound to liver alcohol dehydrogenase by difference techniques.
Topics: Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Deuterium; Kinetics; Liver; NAD; Oxidation-Reduction; Protein Binding; Spectrum Analysis, Raman | 1987 |
A cycling assay for the determination of mono(adenosine-5'-diphosphoribose)-protein bound conjugate levels in mouse tissues.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Brain Chemistry; Female; Kidney; Liver; Mice; Myocardium; NAD; Nucleoside Diphosphate Sugars; Protein Binding; Proteins; Temperature | 1986 |
Allosteric and non-allosteric forms of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase: differential inhibition of activity by adenosine 2'-monophospho-5'-diphosphoribose.
Topics: Adenosine Diphosphate Ribose; Allosteric Regulation; Animals; Female; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Microsomes, Liver; NAD; Rats; Rats, Inbred Strains | 1986 |
[Conformation changes in bacterial formate dehydrogenase during complex-formation with cofactor and its analogs].
Topics: Adenosine Diphosphate Ribose; Aldehyde Oxidoreductases; Apoenzymes; Formate Dehydrogenases; NAD; Protein Conformation; Pseudomonas | 1986 |
ADP-ribosylation of a Mr 21,000 membrane protein by type D botulinum toxin.
Topics: Adenosine Diphosphate Ribose; Adrenal Glands; Agmatine; Animals; Arginine; Botulinum Toxins; Brain; Cattle; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Membrane Proteins; Mice; Molecular Weight; NAD; Pancreas | 1987 |
Decrease in ADP-ribosylation of HeLa non-histone proteins from interphase to metaphase.
Topics: Adenosine Diphosphate Ribose; Cell Cycle; Chromosomal Proteins, Non-Histone; Chromosomes; Female; HeLa Cells; Humans; Interphase; Isoelectric Point; Metaphase; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Poly(ADP-ribose) Polymerase Inhibitors; Protein Processing, Post-Translational | 1985 |
Cholera toxin action on rabbit corpus luteum membranes: effects on adenylyl cyclase activity and adenosine diphospho-ribosylation of the stimulatory guanine nucleotide-binding regulatory component.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Corpus Luteum; Electrophoresis, Polyacrylamide Gel; Female; GTP-Binding Proteins; Guanosine Triphosphate; NAD; Nucleoside Diphosphate Sugars; Rabbits | 1985 |
Heart contains two substrates (Mr = 40,000 and 41,000) for pertussis toxin-catalyzed ADP-ribosylation that co-purify with Ns.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Bacterial Toxins; Cell Line; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Mice; Molecular Weight; Myocardium; NAD; Nucleoside Diphosphate Sugars; Peptides; Pertussis Toxin; Rabbits; Virulence Factors, Bordetella | 1985 |
Detection of NAD:arginine ADPribosyltransferases in animal tissues using 125I-labeled 1-(p-hydroxyphenyl) 2-guanidinoethane as ADPribose acceptor.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Erythrocytes; Male; Microsomes, Liver; NAD; NADP; Pentosyltransferases; Rats; Substrate Specificity; Turkeys; Tyramine | 1985 |
Cellular regulation of poly(ADP) ribosylation of proteins. I. Comparison of hepatocytes, cultured cells and liver nuclei and the influence of varying concentrations of NAD.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Cell Line; Cell Nucleus; Cells, Cultured; Drosophila; Female; Glycoside Hydrolases; Humans; Kinetics; Liver; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains | 1985 |
The stimulatory and inhibitory guanine nucleotide-binding proteins of adenylate cyclase in erythrocytes from patients with pseudohypoparathyroidism type I.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catalysis; Dithiothreitol; Enzyme Activation; Erythrocyte Membrane; GTP-Binding Proteins; Humans; In Vitro Techniques; Mice; NAD; Pertussis Toxin; Pseudohypoparathyroidism; Virulence Factors, Bordetella | 1985 |
Reduced ribosomal binding of eukaryotic elongation factor 2 following ADP-ribosylation. Difference in binding selectivity between polyribosomes and reconstituted monoribosomes.
Topics: Adenosine Diphosphate Ribose; Animals; Diphtheria Toxin; Guanosine Diphosphate; Guanosine Triphosphate; NAD; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Binding; Rabbits; Rats; Ribosomes; Structure-Activity Relationship | 1985 |
Variations in ADP-ribosylation of nuclear scaffold proteins during the HeLa cell cycle.
Topics: Adenine Nucleotides; Adenosine Diphosphate Ribose; Benzamides; Cell Cycle; Cell Nucleus; Dinucleoside Phosphates; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Lamins; NAD; Nucleoproteins; Nucleoside Diphosphate Sugars | 1985 |
Requirements for the translocation of diphtheria toxin fragment A across lipid membranes.
Topics: Adenosine Diphosphate Ribose; Diphtheria Toxin; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Membrane Lipids; NAD; Peptide Elongation Factors; Time Factors | 1985 |
Cell cycle variations in ADP-ribosylation of HeLa nuclear proteins.
Topics: Adenosine Diphosphate Ribose; Cell Cycle; Densitometry; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Interphase; Metaphase; NAD; Nucleoproteins; Nucleoside Diphosphate Sugars; Peptide Fragments | 1985 |
Protein ADP-ribosylation in rat liver cytosol.
Topics: Adenosine Diphosphate Ribose; Animals; Cytosol; Electrophoresis, Polyacrylamide Gel; Liver; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Phosphoric Diester Hydrolases; Poly Adenosine Diphosphate Ribose; Protein Processing, Post-Translational; Proteins; Rats; Trypsin | 1983 |
Endogenous ADP-ribosylation of elongation factor 2 in polyribosome fraction of rabbit reticulocytes.
Topics: Adenosine Diphosphate Ribose; Animals; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerases; Polyribosomes; Rabbits; Reticulocytes | 1984 |
Overview of poly(ADP-ribosyl)ation.
Topics: Adenosine Diphosphate Ribose; Animals; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational | 1984 |
Crystallographic investigations of nicotinamide adenine dinucleotide binding to horse liver alcohol dehydrogenase.
Topics: Adenine; Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallography; Diphosphates; Liver; Molecular Conformation; NAD; Niacinamide; Nicotinamide Mononucleotide; Protein Conformation; Ribose | 1984 |
Functional homology between signal-coupling proteins. Cholera toxin inactivates the GTPase activity of transducin.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cholera Toxin; GTP Phosphohydrolases; Guanylyl Imidodiphosphate; Kinetics; Light; Membrane Proteins; NAD; Phosphoric Monoester Hydrolases; Photoreceptor Cells; Rod Cell Outer Segment; Transducin | 1982 |
ADP-ribosylation of isolated rat islets of Langerhans.
Topics: Adenosine Diphosphate Ribose; Animals; Arginine; Cell Membrane; In Vitro Techniques; Islets of Langerhans; Kinetics; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Rats; Rats, Inbred Lew; Theophylline; Tritium | 1984 |
Agonist-promoted coupling of the beta-adrenergic receptor with the guanine nucleotide regulatory protein of the adenylate cyclase system.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Enzyme Activation; Guanosine Triphosphate; Membrane Proteins; Molecular Weight; NAD; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes | 1980 |
ADP-ribosylation of nuclear proteins in normal lymphocytes and in low-grade malignant non-Hodgkin lymphoma cells.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; B-Lymphocytes; DNA Replication; Humans; Kinetics; Leukemia, Lymphoid; Lymphocytes; Lymphoma; NAD; Nucleoproteins; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Reference Values; Thymidine | 1980 |
Effects of GTP on choleragen-catalyzed ADP ribosylation of membrane and soluble proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cattle; Cholera Toxin; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Membrane Proteins; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Proteins; Structure-Activity Relationship; Thymus Gland | 1980 |
Self-inactivation of an erythrocyte NAD glycohydrolase.
Topics: Adenosine Diphosphate Ribose; Animals; Binding, Competitive; Cattle; Erythrocyte Membrane; Erythrocytes; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; NAD; NAD+ Nucleosidase; NADP | 1980 |
Arrest of mammary tumor growth in vivo by L-arginine: stimulation of NAD-dependent activation of adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Arginine; Bucladesine; Cell Division; Female; Kinetics; Mammary Neoplasms, Experimental; NAD; Rats | 1980 |
Studies of microbial toxins in Xenopus laevis oocytes.
Topics: Adenosine Diphosphate Ribose; Animals; Cholera Toxin; Cyclic AMP; Diphtheria Toxin; Egg Proteins; Female; Kinetics; Molecular Weight; NAD; Oocytes; Ovum; Peptide Fragments; Progesterone; Protein Biosynthesis; Xenopus | 1980 |
Interaction of dinucleotides with muscle phosphofructokinase.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Cyclic AMP; Dithionitrobenzoic Acid; Kinetics; Muscles; NAD; NADP; Nucleoside Diphosphate Sugars; Oxidation-Reduction; Phosphofructokinase-1; Protein Binding; Rabbits | 1981 |
Hormonal stimulation of eucaryotic cell ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Animals; Bucladesine; Cells, Cultured; Dogs; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Proteins; Thymidine; Thyroid Gland; Thyrotropin | 1981 |
Occurrence of the adenylate cyclase "G protein" in membranes of Dictyostelium discoideum.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Cell Membrane; Cholera Toxin; Dictyostelium; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Molecular Weight; NAD; Receptors, Cell Surface | 1981 |
NAD-glycohydrolase activity of staphylococcal entertoxin A (SEA).
Topics: Adenosine Diphosphate Ribose; Cholera Toxin; Dithiothreitol; Enterotoxins; Kinetics; NAD; NAD+ Nucleosidase; Nucleoside Diphosphate Sugars | 1981 |
Mono- and poly-ADP-ribosylation of proteins in mouse kidney after castration and testosterone treatment.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Castration; Kidney; Male; Mice; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Binding; Proteins; Testosterone | 1981 |
Synthesis, characterisation and biological significance of (2'-5')oligoadenylate derivatives of NAD+, ADP-ribose and adenosine(5')tetraphospho(5')adenosine.
Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Adenosine Diphosphate Ribose; Animals; Carcinoma, Ehrlich Tumor; Cell-Free System; Cells, Cultured; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Mice; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Oligonucleotides; Oligoribonucleotides | 1982 |
Adenosine diphosphate-ribosyltransferase activity in permeabilized mouse testicular cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cells, Cultured; Male; Mice; NAD; Nucleotidyltransferases; Permeability; Poly(ADP-ribose) Polymerases; Sertoli Cells; Testis | 1982 |
ADP-ribosyl-protein conjugate subclasses in various tissues. Specific influence of thyroid hormone on liver conjugates.
Topics: Adenosine Diphosphate Ribose; Animals; Electron Transport Complex IV; Hydroxylamine; Hydroxylamines; Hypothyroidism; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred BALB C; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Proteins; Thyroxine; Tissue Distribution | 1982 |
Characterization of the GTP-binding component of the adenylate cyclase system in isolated myocardial muscle cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Blood Proteins; Cell Membrane; Cholera Toxin; Enzyme Activation; GTP-Binding Proteins; Myocardium; NAD; Rats; Receptors, Cell Surface | 1982 |
Identification of the predominant substrate for ADP-ribosylation by islet activating protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Bacterial Proteins; Blood Proteins; Chromatography, Affinity; GTP-Binding Proteins; Liver; Macromolecular Substances; Membrane Proteins; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Pertussis Toxin; Rabbits; Receptors, Cell Surface; Virulence Factors, Bordetella | 1983 |
A note on the ADP-ribose-protein linkages in rat-liver nuclei: a possible approach to assessing megavitamin therapy with niacin.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Nucleus; Chemical Phenomena; Chemistry; Female; Hydroxylamine; Hydroxylamines; Liver; NAD; Niacin; Nucleoside Diphosphate Sugars; Orthomolecular Therapy; Phosphoric Diester Hydrolases; Proteins; Rats | 1983 |
Ca2+, Mg2+ and (adenosine diphosphate ribose)n in cellular response to irradiation.
Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Chromatin; Cyclic AMP; Dinitrophenols; DNA Replication; Glycoside Hydrolases; Magnesium; Mitochondria; Models, Biological; NAD; Nucleoside Diphosphate Sugars; Oxygen; Poly(ADP-ribose) Polymerase Inhibitors; Polyamines; Radiation Tolerance | 1983 |
Activation by thiol of the latent NAD glycohydrolase and ADP-ribosyltransferase activities of Bordetella pertussis toxin (islet-activating protein).
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Bacterial Proteins; Bordetella pertussis; Cell Line; Dithiothreitol; Enzyme Activation; Erythrocyte Membrane; Glioma; Hybrid Cells; Islets of Langerhans; Kinetics; Mice; NAD; NAD+ Nucleosidase; Neuroblastoma; Nucleotidyltransferases; Pertussis Toxin; Poly(ADP-ribose) Polymerases; Rats; Sulfhydryl Compounds; Virulence Factors, Bordetella | 1983 |
Selective regulation by pertussis toxin of insulin-induced activation of particulate cAMP phosphodiesterase activity in 3T3-L1 adipocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate Ribose; Adipose Tissue; Animals; Bacterial Toxins; Cell Line; Enzyme Activation; Insulin; Isoproterenol; Mice; NAD; Pertussis Toxin; Virulence Factors, Bordetella | 1983 |
Mono- and poly(ADP-ribose) metabolism following DNA damage.
Topics: Adenosine Diphosphate Ribose; Benzamides; DNA; DNA Repair; Fibroblasts; Methylnitronitrosoguanidine; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Theophylline; Ultraviolet Rays | 1983 |
Mechanism of the inhibition of Ca2+, Mg2+-dependent endonuclease of bull seminal plasma induced by ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Endodeoxyribonucleases; Kinetics; Male; NAD; NAD+ Nucleosidase; Nucleoside Diphosphate Sugars; Poly(ADP-ribose) Polymerases; Protein Binding; Semen; Tritium | 1984 |
Limulus ventral photoreceptors contain a homologue of the alpha-subunit of mammalian Ns.
Topics: Adenosine Diphosphate Ribose; Adipose Tissue; Animals; Cholera Toxin; Endopeptidases; GTP-Binding Proteins; Horseshoe Crabs; Liver; Membrane Proteins; Molecular Weight; NAD; Pancreatic Elastase; Photoreceptor Cells; Rats; Receptors, Cell Surface; Rod Cell Outer Segment; Serine Endopeptidases | 1984 |
Pertussis toxin catalyzes the ADP-ribosylation of two distinct peptides, 40 and 41 kDa, in rat fat cell membranes.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adipose Tissue; Animals; Bacterial Toxins; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Liver; Lymphoma; Membrane Proteins; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Peptide Hydrolases; Pertussis Toxin; Rats; Rats, Inbred Strains; Thionucleotides; Virulence Factors, Bordetella | 1984 |
Diphthamide in elongation factor 2: ADP-ribosylation, purification, and properties.
Topics: Adenosine Diphosphate Ribose; Diphtheria Toxin; Histidine; NAD; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorus Radioisotopes; Protein Processing, Post-Translational; Radioisotope Dilution Technique | 1984 |
ADP-ribosylation in permeable HeLa S3 cells.
Topics: Adenosine Diphosphate Ribose; Autoradiography; Cell Membrane Permeability; DNA; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases | 1983 |
[Pertussis toxin stimulates brain adenyl cyclase and induces ADP ribosylation of a 40,000 dalton membrane protein].
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bacterial Toxins; Brain; Colforsin; Diterpenes; Guanosine Triphosphate; Membrane Proteins; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Pertussis Toxin; Rats; Synaptic Membranes; Virulence Factors, Bordetella | 1983 |
Increase of mono(ADP-ribose) protein conjugate levels in rat liver induced by nicotinamide administration.
Topics: Adenosine Diphosphate Ribose; Animals; Hydroxylamines; Liver; Liver Neoplasms, Experimental; NAD; NADP; Niacinamide; Nucleoside Diphosphate Sugars; Oxidation-Reduction; Protein Binding; Proteins; Rats | 1980 |
Requirement for guanosine triphosphate for cholera-toxin-catalysed incorporation of adenosine diphosphate ribose into rat liver plasma membranes and for activation of adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Female; Guanosine Triphosphate; In Vitro Techniques; Liver; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Rats | 1980 |
Artificial low-molecular-mass substrates of cholera toxin.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Guanidine; Guanidines; Hydrolysis; Liver; Models, Chemical; NAD; Rats; Structure-Activity Relationship | 1984 |
ADP-ribosylation in inner membrane of rat liver mitochondria.
Topics: Adenosine Diphosphate Ribose; Animals; Carbon Radioisotopes; Female; Intracellular Membranes; Kinetics; Mitochondria; Mitochondria, Liver; NAD; Nucleoside Diphosphate Sugars; Rats; Rats, Inbred Strains; Submitochondrial Particles | 1983 |
ADP-ribosylation of transducin by islet-activation protein. Identification of asparagine as the site of ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Asparagine; Bacterial Proteins; Carboxypeptidases; Cattle; Cholera Toxin; Mass Spectrometry; Membrane Proteins; NAD; Nucleoside Diphosphate Sugars; Pertussis Toxin; Rod Cell Outer Segment; Transducin; Virulence Factors, Bordetella | 1984 |
Nonenzymic ADP-ribosylation of specific mitochondrial polypeptides.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Electrophoresis, Polyacrylamide Gel; Kinetics; Mitochondria; Mitochondria, Heart; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Peptides; Submitochondrial Particles; Tritium | 1984 |
Regulation of repair of naturally occurring DNA strand breaks in lymphocytes.
Topics: Adenosine Diphosphate Ribose; Animals; Concanavalin A; DNA Repair; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NAD; Spleen; T-Lymphocytes | 1984 |
ADP-ribosylation of nonhistone proteins during the HeLa cell cycle.
Topics: Adenosine Diphosphate Ribose; Cell Cycle; Cell Nucleus; Chromosomal Proteins, Non-Histone; HeLa Cells; Humans; Kinetics; Metaphase; Mitosis; Molecular Weight; NAD; Nucleoside Diphosphate Sugars | 1983 |
Bovine lens aldehyde dehydrogenase. Kinetics and mechanism.
Topics: Adenosine Diphosphate Ribose; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Cattle; Chloral Hydrate; Kinetics; Lens, Crystalline; NAD; Substrate Specificity; Sulfhydryl Compounds; Sulfhydryl Reagents | 1983 |
The A protomer of islet-activating protein, pertussis toxin, as an active peptide catalyzing ADP-ribosylation of a membrane protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bacterial Proteins; Catalysis; Membrane Proteins; NAD; Nucleoside Diphosphate Sugars; Peptide Fragments; Pertussis Toxin; Rats; Virulence Factors, Bordetella | 1983 |
ADP-ribosyl protein lyase. Purification, properties, and identification of the product.
Topics: Adenosine Diphosphate Ribose; Animals; Carbon-Oxygen Lyases; Chemical Phenomena; Chemistry; Chromatography, Paper; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Lyases; NAD; NADP; Rats; Rats, Inbred Strains; Substrate Specificity | 1984 |
ADP-ribosylation of microtubule proteins as catalyzed by cholera toxin.
Topics: Adenosine Diphosphate Ribose; Animals; Brain Chemistry; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Kinetics; Male; Microtubule-Associated Proteins; NAD; Nucleoside Diphosphate Sugars; Proteins; Rats; Serine Endopeptidases; Tubulin | 1982 |
Control by phospho-adenosinediphospho-ribose of NADP-dependent isocitrate dehydrogenase and 6-phosphogluconate dehydrogenase in Streptomyces griseus.
Topics: Adenosine Diphosphate Ribose; Cell-Free System; Isocitrate Dehydrogenase; Mutation; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; NADP; Nucleoside Diphosphate Sugars; Phosphogluconate Dehydrogenase; Streptomyces; Streptomyces griseus; Streptomycin | 1980 |
ADP-ribosylation of pancreatic histone H1 and of other histones.
Topics: Adenosine Diphosphate Ribose; Animals; Chromatin; Histones; NAD; Nucleoside Diphosphate Sugars; Pancreas; Poly(ADP-ribose) Polymerases; Rats | 1980 |
Decrease of hepatic mono and oligo adenosine diphosphoribose content and augmentation of [14C]ribose incorporation during induction of growth by bovine growth hormone in hypophysectomized rats.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Body Weight; Female; Growth Hormone; Hypophysectomy; Kinetics; Liver; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Rats; Ribose | 1981 |
DNA fragmentation and NAD depletion. Their relation to the turnover of endogenous mono(ADP-ribosyl) and poly(ADP-ribosyl) proteins.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Kinetics; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Triaziquone | 1982 |
ADP-ribosylation of brain synaptosomal proteins correlates with adenylate cyclase activation.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Brain; Cholera Toxin; Egtazic Acid; Enzyme Activation; Guanosine Triphosphate; Membrane Proteins; Molecular Weight; NAD; Nerve Tissue Proteins; Nucleoside Diphosphate Sugars; Rats; Synaptosomes | 1982 |
NAD+-induced inhibition of phosphate transport in canine renal brush-border membranes. Mediation through a process other than or in addition to NAD+ hydrolysis.
Topics: Adenosine Diphosphate Ribose; Animals; Biological Transport; Cell Membrane; Dogs; Kidney; Magnesium; Membrane Proteins; Microvilli; Molecular Weight; NAD; Phosphates; Sodium | 1983 |
Nucleotide inhibition of phosphate transport in the renal proximal tubule.
Topics: Adenine Nucleotides; Adenosine Diphosphate Ribose; Animals; Biological Transport; Guanosine Diphosphate; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Microvilli; NAD; Phosphates; Rabbits; Ribonucleotides; Structure-Activity Relationship; Theophylline | 1983 |
Mechanism of negative cooperativity in glyceraldehyde-3-phosphate dehydrogenase deduced from ligand competition experiments.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Glyceraldehyde-3-Phosphate Dehydrogenases; Ligands; Models, Biological; NAD; Protein Binding; Protein Conformation; Rabbits | 1980 |
Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Line; Cell-Free System; Glioma; Kinetics; Membrane Proteins; NAD; Nucleoside Diphosphate Sugars; Rats | 1982 |
Poly(ADP-ribose) synthesis, a marker of granulocyte differentiation.
Topics: Adenosine Diphosphate Ribose; Bone Marrow Cells; Cell Differentiation; Fluorescent Antibody Technique; Granulocytes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocytes; NAD; Nucleoside Diphosphate Sugars | 1980 |
ADP-ribosylation of sarcolemma membrane proteins in the presence of cholera toxin and its influence on insulin-stimulated membrane protein kinase activity.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Cholera Toxin; Guanosine Triphosphate; Insulin; Membrane Proteins; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Protein Kinases; Sarcolemma | 1981 |
Investigation of the nature of enzyme--coenzyme interactions in binary and ternary complexes of liver alcohol dehydrogenase with coenzymes, coenzyme analogues, and substrate analogues by ultraviolet absorption and phosphorescence spectroscopy.
Topics: Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Binding Sites; Horses; Kinetics; Liver; Luminescent Measurements; Molecular Conformation; NAD; Oxidation-Reduction; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet | 1981 |
Synergism between coenzyme and carboxylate binding to liver alcohol dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Carboxylic Acids; Horses; Kinetics; Liver; NAD; Oxidation-Reduction; Protein Binding | 1981 |
Plasma membrane-associated component(s) that confer(s) cholera toxin sensitivity to adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Chromatography, Gel; Cytosol; Drug Stability; Enzyme Activation; Guanosine Triphosphate; Kidney; Membrane Proteins; NAD; Rats | 1982 |
Peptide mapping of fat cell membrane substrates for cholera toxin-catalyzed ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Adipose Tissue; Animals; Cholera Toxin; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Membrane Proteins; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Rats | 1982 |
ADP-ribosylation of membrane proteins in cholinergic nerve terminals.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Electric Organ; Enzyme Activation; Membrane Proteins; NAD; Nucleoside Diphosphate Sugars; Receptors, Cholinergic; Synaptic Vesicles; Synaptosomes; Torpedo | 1982 |
Mono ADP-ribosylation and poly ADP-ribosylation of proteins in normal and malignant tissues.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Differentiation; DNA Repair; Hydroxylamines; Liver; Liver Neoplasms, Experimental; NAD; Neoplasm Proteins; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Proteins; Subcellular Fractions | 1982 |
ADP ribosylation of canine renal brush border membrane vesicle proteins is associated with decreased phosphate transport.
Topics: Adenosine Diphosphate Ribose; Animals; Biological Transport; Chromatography, High Pressure Liquid; Dogs; Electrophoresis, Polyacrylamide Gel; Kidney; Membrane Proteins; Microvilli; NAD; Nucleoside Diphosphate Sugars; Phosphates; Sodium | 1982 |
Tubulin adenosine diphosphate ribosylation is catalyzed by cholera toxin.
Topics: Adenosine Diphosphate Ribose; Animals; Brain Chemistry; Cattle; Cell Line; Cell Membrane; Cholera Toxin; Cytosol; Glioma; Guanosine Triphosphate; NAD; Nucleoside Diphosphate Sugars; Rats; Tubulin | 1982 |
A word of caution: 1,4,5,6-tetrahydronicotinamide adenine dinucleotide (phosphate) should be used with care in acidic and neutral media.
Topics: Adenosine Diphosphate Ribose; Chemical Phenomena; Chemistry; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; NAD | 1982 |
Determination of 5-AMP in the presence of excess 3'(2')-AMP with the aid of antibodies raised against n6-carboxymethyl-5'-AMP conjugates. Use for the quantitation of pyridine nucleotides and of protein-bound ADP-ribose.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Antibody Formation; NAD; Rabbits; Serum Albumin, Bovine; Substrate Specificity | 1981 |
Endogenous and cholera toxin-catalyzed ADP-ribosylation of a plasma membrane protein by RL-PR-C cloned rat hepatocytes.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Amino Acids; Animals; Arginine; Cell Line; Cell Membrane; Cholera Toxin; Clone Cells; Kinetics; Liver; Membrane Proteins; NAD; Nucleoside Diphosphate Sugars; Rats | 1981 |
ADP ribosylation of membrane proteins from human fibroblasts. Effect of prior exposure of cells to choleragen.
Topics: Adenosine Diphosphate Ribose; Cell Membrane; Cholera Toxin; Dose-Response Relationship, Drug; Fibroblasts; Humans; Kinetics; Membrane Proteins; Molecular Weight; NAD; Nucleoside Diphosphate Sugars; Skin | 1981 |
Poly(ADP-ribose) synthesis in nucleoli and ADP-ribosylation of nucleolar proteins in mouse ascites tumor cells in vitro.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Fractionation; Cell Nucleolus; Chromatin; Histones; Magnesium; Mice; Molecular Weight; NAD; Nucleoproteins; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose | 1981 |
Covalent modification of proteins by metabolites of NAD+.
Topics: Adenosine Diphosphate Ribose; Kinetics; Mitochondria, Liver; NAD; Nucleoside Diphosphate Sugars; Proteins | 1980 |
Protein-bound mono(ADP-ribose) residues in differentiating cells of Dictyostelium discoideum.
Topics: Adenosine Diphosphate Ribose; Cell Cycle; Cell Nucleus; Dictyostelium; DNA; NAD; NADP; Nucleoside Diphosphate Sugars; Proteins | 1980 |
Demonstration of choleragen-dependent ADP-ribosylation in whole cells and correlation with the activation of adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane Permeability; Cholera Toxin; Clone Cells; Columbidae; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Fibroblasts; Hydrogen-Ion Concentration; Mice; NAD; Nucleoside Diphosphate Sugars; Peptides | 1980 |
ADP-ribosyltransferase activity of mono- and multi-(ADP-ribosylated) choleragen.
Topics: Adenosine Diphosphate Ribose; Arginine; Cholera Toxin; Dithiothreitol; NAD; Nucleoside Diphosphate Sugars; Pentosyltransferases | 1980 |
ADP-ribosylation in mammalian cell ghosts. Dependence of poly(ADP-ribose) synthesis on strand breakage in DNA.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; DNA; HeLa Cells; Humans; Kinetics; L Cells; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose | 1980 |
Ligand interactions of diphtheria toxin. II. Relationships between the NAD site and the P site.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Binding Sites; Diphtheria Toxin; Kinetics; Ligands; NAD; Protein Binding | 1980 |
The sequential nature of the negative cooperativity in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Binding, Competitive; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; Macromolecular Substances; Muscles; NAD; Rabbits; Spectrometry, Fluorescence | 1980 |
Mechanism of inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Binding, Competitive; Enzyme Inhibitors; Glycoside Hydrolases; Kinetics; Molecular Structure; NAD; Niacinamide; Pyrrolidines | 1995 |
In vitro ADP-ribosylation of Rho by bacterial ADP-ribosyltransferases.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Animals; Asparagine; Autoradiography; Bacteria; Botulinum Toxins; Brain; Cattle; Cell Line; Clostridium botulinum; Detergents; Dimyristoylphosphatidylcholine; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Kidney; Kinetics; Liver Neoplasms, Experimental; NAD; Phosphorus Radioisotopes; Poly(ADP-ribose) Polymerases; Rats; Tumor Cells, Cultured | 1995 |
Preparation of native and recombinant Clostridium botulinum C3 ADP-ribosyltransferase and identification of Rho proteins by ADP-ribosylation.
Topics: 3T3 Cells; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Autoradiography; Blotting, Western; Botulinum Toxins; Cell Line; Cloning, Molecular; Clostridium botulinum; Electrophoresis, Polyacrylamide Gel; Escherichia coli; GTP-Binding Proteins; HeLa Cells; HL-60 Cells; Humans; Indicators and Reagents; Kinetics; Mice; NAD; Organ Specificity; PC12 Cells; Phosphorus Radioisotopes; Rats; Recombinant Proteins; Tumor Cells, Cultured | 1995 |
Reduction of mono(ADP-ribosyl)ation of histones in rat testis by gonadotropin-testosterone system.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Animals; Cell Nucleus; Follicle Stimulating Hormone; Histones; Luteinizing Hormone; Male; Molecular Sequence Data; NAD; Nuclear Proteins; Peptide Fragments; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Testis; Testosterone | 1995 |
Equilibrium model in an in vitro poly(ADP-ribose) turnover system.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Chromatography, High Pressure Liquid; Glycoside Hydrolases; Kinetics; Mathematics; Models, Theoretical; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Thymus Gland | 1995 |
ADP-ribosylation of human myelin basic protein.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Cholera Toxin; Chromatography, High Pressure Liquid; Complement C1; Electrophoresis, Polyacrylamide Gel; Humans; Hydroxylamine; Hydroxylamines; Molecular Sequence Data; Myelin Basic Protein; NAD; Signal Transduction | 1994 |
Can wound healing be a paradigm for tissue repair?
Topics: Adenosine Diphosphate Ribose; Animals; Collagen; Exercise Therapy; Humans; Lactates; Models, Biological; Muscles; NAD; Neovascularization, Pathologic; Rabbits; Wound Healing | 1994 |
ADP-ribosylation of Rho enhances adhesion of U937 cells to fibronectin via the alpha 5 beta 1 integrin receptor.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Botulinum Toxins; Cell Adhesion; Cell Line; Fibronectins; GTP-Binding Proteins; GTPase-Activating Proteins; Humans; Integrins; NAD; Receptors, Fibronectin | 1995 |
Melatonin receptors couple through a cholera toxin-sensitive mechanism to inhibit cyclic AMP in the ovine pituitary.
Topics: Adenosine Diphosphate Ribose; Animals; Base Sequence; Blotting, Northern; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Iodine Radioisotopes; Melatonin; Molecular Sequence Data; NAD; Pertussis Toxin; Pituitary Gland; Receptors, Cell Surface; Receptors, Melatonin; RNA, Messenger; Sheep; Virulence Factors, Bordetella | 1995 |
Stimulatory guanine nucleotide binding protein in pig epidermis: transient increase of the 45KDA cholera toxin substrate (Gs alpha) in the tape stripping-induced hyperproliferative state.
Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Cell Fractionation; Cell Membrane; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epidermal Cells; Epidermis; GTP-Binding Proteins; Histological Techniques; Kinetics; Molecular Weight; NAD; Phosphorus Radioisotopes; Swine | 1994 |
NAD(+)-dependent ADP-ribosylation of T lymphocyte alloantigen RT6.1 reversibly proceeding in intact rat lymphocytes.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; ADP Ribose Transferases; Animals; Antigens, Differentiation, T-Lymphocyte; Arginine; ATP-Binding Cassette Transporters; Binding Sites; Carrier Proteins; Cells, Cultured; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Gene Expression; Glycosylphosphatidylinositols; Histocompatibility Antigens; Isoantigens; Maltose; Maltose-Binding Proteins; Membrane Glycoproteins; Monosaccharide Transport Proteins; NAD; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Phosphorus Radioisotopes; Rats; Recombinant Fusion Proteins; RNA, Messenger; Snake Venoms; T-Lymphocytes | 1995 |
Agonist-stimulated cyclic ADP ribose. Endogenous modulator of Ca(2+)-induced Ca2+ release in intestinal longitudinal muscle.
Topics: Adenosine Diphosphate Ribose; Animals; Benzodiazepinones; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Membrane Permeability; Cyclic ADP-Ribose; Devazepide; Dose-Response Relationship, Drug; Guanosine Diphosphate; Heparin; Intestine, Small; Muscle Contraction; Muscle, Smooth; NAD; Nifedipine; Rabbits; Ruthenium Red; Sincalide; Subcellular Fractions; Thionucleotides | 1995 |
Nitric oxide stimulates ADP ribosylation of actin in association with the inhibition of actin polymerization in human neutrophils.
Topics: Actins; Adenosine Diphosphate Ribose; Botulinum Toxins; Cell Adhesion; Electrophoresis, Polyacrylamide Gel; Fibronectins; Humans; In Vitro Techniques; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NAD; Neutrophils; Nitric Oxide; Peptide Mapping; Spectrometry, Fluorescence | 1995 |
Evidence for unusual stability of ADP-ribosyl linkage to membrane proteins of a murine leukemic cell line.
Topics: Adenosine Diphosphate Ribose; Animals; Benzamides; Cell Differentiation; Chromatography, Gel; Drug Stability; Granulocyte Colony-Stimulating Factor; Granulocytes; Leukemia, Experimental; Membrane Proteins; Mice; NAD; Recombinant Proteins; Tumor Cells, Cultured | 1993 |
cGMP mobilizes intracellular Ca2+ in sea urchin eggs by stimulating cyclic ADP-ribose synthesis.
Topics: Adenosine Diphosphate Ribose; Aniline Compounds; Animals; Calcium; Cyclic ADP-Ribose; Cyclic GMP; Fluorometry; In Vitro Techniques; Microsomes; NAD; Ovum; Ruthenium Red; Sea Urchins; Signal Transduction; Xanthenes | 1993 |
Nicotinamide-adenine dinucleotide regulates muscarinic receptor-coupled K+ (M) channels in rodent NG108-15 cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cyclic ADP-Ribose; Mice; NAD; Potassium Channels; Receptors, Muscarinic; Streptozocin; Swine; Tumor Cells, Cultured | 1995 |
Time course of action of pertussis toxin to block the inhibition of stimulated insulin release by norepinephrine.
Topics: Adenosine Diphosphate Ribose; Animals; Blotting, Western; Colforsin; Cyclic AMP; Glucose; GTP-Binding Proteins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; NAD; Norepinephrine; Pertussis Toxin; Propranolol; Rats; Rats, Sprague-Dawley; Time Factors; Virulence Factors, Bordetella | 1995 |
Processing of ADP-ribosylated integrin alpha 7 in skeletal muscle myotubes.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antigens, CD; Cells, Cultured; Integrin alpha Chains; Integrins; Mice; Muscle, Skeletal; NAD; Poly(ADP-ribose) Polymerases | 1995 |
The kinetics of cyclic ADP-ribose formation in heart muscle.
Topics: Adenosine Diphosphate Ribose; Animals; Cyclic ADP-Ribose; In Vitro Techniques; Kinetics; Male; Myocardium; NAD; Rats; Rats, Sprague-Dawley | 1995 |
Cyclic ADP-ribose and related compounds activate sheep skeletal sarcoplasmic reticulum Ca2+ release channel.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cyclic ADP-Ribose; Muscle, Skeletal; NAD; Osmolar Concentration; Sarcoplasmic Reticulum; Sheep | 1995 |
Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Survival; DNA Damage; Female; Hot Temperature; HSP70 Heat-Shock Proteins; In Vitro Techniques; Islets of Langerhans; Male; NAD; Nitric Oxide; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Time Factors | 1995 |
Large supplements of nicotinic acid and nicotinamide increase tissue NAD+ and poly(ADP-ribose) levels but do not affect diethylnitrosamine-induced altered hepatic foci in Fischer-344 rats.
Topics: Adenosine Diphosphate Ribose; Animals; Diethylnitrosamine; Food, Fortified; Glutathione Transferase; Kidney; Liver; Lung; Male; Myocardium; NAD; Niacin; Niacinamide; Rats; Rats, Inbred F344 | 1995 |
Common features of the NAD-binding and catalytic site of ADP-ribosylating toxins.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Arginine; Bacillus; Bacterial Toxins; Binding Sites; Catalysis; Cholera Toxin; Computer Graphics; Conserved Sequence; Diphtheria Toxin; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Exotoxins; Histidine; Models, Molecular; Molecular Sequence Data; NAD; Pertussis Toxin; Protein Structure, Secondary; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Sequence Homology, Amino Acid; Virulence Factors; Virulence Factors, Bordetella | 1994 |
Self-aggregation of purified and membrane-bound erythrocyte CD38 induces extensive decrease of its ADP-ribosyl cyclase activity.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Erythrocyte Membrane; Glutathione; Humans; Macromolecular Substances; Membrane Glycoproteins; Mercaptoethanol; N-Glycosyl Hydrolases; NAD | 1995 |
Specificity of G protein alpha-gamma subunit interactions. N-terminal 15 amino acids of gamma subunit specifies interaction with alpha subunit.
Topics: Adenosine Diphosphate Ribose; Animals; Baculoviridae; Binding Sites; Brain; Cattle; Cell Line; Cell Membrane; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Immunoblotting; Macromolecular Substances; Molecular Weight; NAD; Peptide Fragments; Pertussis Toxin; Recombinant Fusion Proteins; Recombinant Proteins; Spodoptera; Transfection; Trypsin; Virulence Factors, Bordetella | 1995 |
Ligation of CD38 suppresses human B lymphopoiesis.
Topics: Adenosine Diphosphate Ribose; Adolescent; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Adult; Antigens, CD; Antigens, Differentiation; Apoptosis; B-Lymphocytes; Cell Division; Cells, Cultured; Child; Child, Preschool; Cyclic ADP-Ribose; Hematopoiesis; Hematopoietic Stem Cells; Humans; Infant; Membrane Glycoproteins; NAD | 1995 |
Analysis of the relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these polypeptides in rat 1 fibroblasts.
Topics: Adenosine Diphosphate Ribose; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cholera Toxin; Fibroblasts; Gene Expression; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Immunosorbent Techniques; NAD; Pertussis Toxin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Transfection; Virulence Factors, Bordetella; Yohimbine | 1995 |
In the thermophilic archaeon Sulfolobus solfataricus a DNA-binding protein is in vitro (Adpribosyl)ated.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Amino Acids; Animals; Cattle; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; DNA-Binding Proteins; DNA, Bacterial; Glutamic Acid; Histones; Hot Temperature; Lysine; Molecular Sequence Data; Molecular Weight; NAD; Nucleic Acid Denaturation; Peptide Fragments; Sulfolobus | 1995 |
Trypanosoma brucei: characterisation of a life cycle stage-specific G-protein.
Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Blotting, Western; Cholera Toxin; Cross Reactions; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine Triphosphate; Immune Sera; Luminescent Measurements; NAD; Pertussis Toxin; Protozoan Proteins; Species Specificity; Trypanosoma brucei brucei; Virulence Factors, Bordetella | 1995 |
DeoxyNAD and deoxyADP-ribosylation of proteins.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Chromatin; Molecular Structure; NAD; Poly(ADP-ribose) Polymerases; Proteins | 1994 |
Alterations in G-proteins in congestive heart failure in cardiomyopathic (UM-X7.1) hamsters.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cardiomyopathies; Cholera Toxin; Colforsin; Cricetinae; Dihydroalprenolol; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart; Heart Failure; Myocardium; NAD; Norepinephrine; Pertussis Toxin; Sarcolemma; Sodium Fluoride; Virulence Factors, Bordetella | 1994 |
Metabolism of cyclic ADP-ribose in opossum kidney renal epithelial cells.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Biological Assay; Calcium; Carrier Proteins; Cell Line; Cell Membrane Permeability; Cyclic ADP-Ribose; Epithelium; Kidney; N-Glycosyl Hydrolases; NAD; Niacinamide; Opossums; Ovum; Parathyroid Hormone; Sea Urchins; Sodium-Phosphate Cotransporter Proteins; Symporters | 1995 |
[Mobilization of intracellular calcium: how to take another path].
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cyclic GMP; Cytoplasm; Enzyme Activation; Guanylate Cyclase; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ion Transport; Muscle Proteins; NAD; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Signal Transduction | 1994 |
Nitric oxide regulation of glyceraldehyde-3-phosphate dehydrogenase activity in Dictyostelium discoideum cells and lysates.
Topics: Adenosine Diphosphate Ribose; Animals; Cysteine; Cytosol; Dictyostelium; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; NAD; Nitric Oxide; Nitroprusside; Oxidation-Reduction | 1994 |
Cyclic ADP-ribose does not affect cardiac or skeletal muscle ryanodine receptors.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cyclic ADP-Ribose; Lipid Bilayers; Muscle Proteins; Myocardium; NAD; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Swine | 1994 |
Purification and separation of closely related members of pertussis toxin-substrate G proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Binding Sites; Cattle; Cell Membrane; Cerebral Cortex; Chromatography, Ion Exchange; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Macromolecular Substances; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Protein Binding; Radioisotope Dilution Technique; Sulfur Radioisotopes; Virulence Factors, Bordetella | 1994 |
Activation of cholera toxin by ADP-ribosylation factors: 20-kDa guanine nucleotide-binding proteins.
Topics: Acyltransferases; Adenosine Diphosphate Ribose; ADP-Ribosylation Factors; Animals; Base Sequence; Brain; Carbon Radioisotopes; Cattle; Cell Membrane; Cholera Toxin; Chromatography, Ion Exchange; Cloning, Molecular; Cytosol; DNA Primers; Genes, Fungal; GTP-Binding Proteins; Humans; Molecular Sequence Data; Molecular Weight; NAD; Poly(ADP-ribose) Polymerases; Polymerase Chain Reaction; Protein Processing, Post-Translational; Radioisotope Dilution Technique; Recombinant Proteins; Saccharomyces cerevisiae | 1994 |
Pertussis toxin-catalyzed ADP-ribosylation of G proteins.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Autoradiography; Brain; Cell Membrane; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Indicators and Reagents; Liver; Molecular Weight; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Virulence Factors, Bordetella | 1994 |
Synthesis and use of radioactive photoactivatable NAD+ derivatives as probes for G-protein structure.
Topics: Adenosine Diphosphate Ribose; Affinity Labels; Animals; Cattle; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Iodine Radioisotopes; Kinetics; Macromolecular Substances; NAD; Peptide Fragments; Phosphorus Radioisotopes; Radioisotope Dilution Technique; Rod Cell Outer Segment; Structure-Activity Relationship; Sulfur Radioisotopes; Transducin; Trypsin | 1994 |
Pancreastatin activates protein kinase C by stimulating the formation of 1,2-diacylglycerol in rat hepatocytes.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cells, Cultured; Chromogranin A; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Guanosine Triphosphate; Kinetics; Liver; Male; NAD; Pancreatic Hormones; Pertussis Toxin; Protein Kinase C; Rats; Rats, Wistar; Virulence Factors, Bordetella | 1994 |
ADP-ribosylation of heterogeneous ribonucleoproteins in HeLa cells.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Electrophoresis, Gel, Two-Dimensional; HeLa Cells; Humans; Molecular Sequence Data; NAD; Ribonucleoproteins; RNA-Binding Proteins; Sequence Homology, Amino Acid | 1994 |
Mechanistic implications of cyclic ADP-ribose hydrolysis and methanolysis catalyzed by calf spleen NAD+glycohydrolase.
Topics: Adenosine Diphosphate Ribose; Animals; Carbon Radioisotopes; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Hydrolysis; Kinetics; Methane; NAD; NAD+ Nucleosidase; Spleen | 1994 |
Characterization of interactions between transducin alpha/beta gamma-subunits and lipid membranes.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Binding Sites; Cattle; Endopeptidases; Hydrogen-Ion Concentration; Kinetics; Liposomes; Macromolecular Substances; Molecular Sequence Data; NAD; Oligopeptides; Peptide Fragments; Phospholipids; Protein Binding; Protein Prenylation; Rod Cell Outer Segment; Structure-Activity Relationship; Transducin; Virulence Factors, Bordetella | 1994 |
Guanine nucleotides and pertussis toxin reduce the affinity of histamine H3 receptors on AtT-20 cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Histamine Agonists; Methylhistamines; Mice; NAD; Pertussis Toxin; Phosphorus Radioisotopes; Pituitary Gland; Receptors, Histamine H3; Signal Transduction; Virulence Factors, Bordetella | 1993 |
Pleiotropic effects of nitric oxide on ADP-ribosylation, covalent binding of NAD, and catalytic activity of glyceraldehyde-3-phosphate and aldehyde dehydrogenases.
Topics: Adenosine Diphosphate Ribose; Aldehyde Dehydrogenase; Binding Sites; Catalysis; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; In Vitro Techniques; NAD; Nitric Oxide; Nitroprusside | 1993 |
Involvement of serine 74 in the enzyme-coenzyme interaction of rat liver mitochondrial aldehyde dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Aldehyde Dehydrogenase; Animals; Coenzymes; Enzyme Stability; Esterases; Kinetics; Mitochondria, Liver; Mutation; NAD; Rats; Recombinant Proteins; Sepharose; Serine; Substrate Specificity | 1994 |
Cell surface antigen CD38 identified as ecto-enzyme of NAD glycohydrolase has hyaluronate-binding activity.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Aplysia; Binding Sites; Chromatography, Affinity; Enzyme Induction; Humans; Hyaluronic Acid; Membrane Glycoproteins; Mice; Molecular Sequence Data; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Sequence Homology; Tretinoin; Tumor Cells, Cultured | 1994 |
Characterization and distribution of alpha 2-adrenergic receptors in the human intestinal mucosa.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Cell Membrane; Colon; Dioxanes; Duodenum; Epinephrine; Epithelium; Humans; Idazoxan; Intestinal Mucosa; Kinetics; Microvilli; NAD; Organ Specificity; Pertussis Toxin; Quinoxalines; Receptors, Adrenergic, alpha; RNA, Messenger; Virulence Factors, Bordetella | 1993 |
Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges.
Topics: Adenosine Diphosphate Ribose; Animals; Base Sequence; Binding Sites; Cell Membrane; Cell Survival; Cloning, Molecular; Cysteine; Diphtheria Toxin; Disulfides; DNA Primers; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Fragments; Protein Biosynthesis; Protein Structure, Secondary; Recombinant Proteins; Transcription, Genetic; Vero Cells | 1994 |
Role of histidine 35 of the S1 subunit of pertussis toxin in the ADP-ribosylation of transducin.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Escherichia coli; Histidine; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligodeoxyribonucleotides; Pertussis Toxin; Point Mutation; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Transducin; Virulence Factors, Bordetella | 1994 |
ADP-ribosylation of human serum proteins promoted by endogenous NAD glycohydrolase activity.
Topics: Adenosine Diphosphate Ribose; Animals; Blood Proteins; Brain; Carbon Radioisotopes; Humans; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; NAD; NAD+ Nucleosidase; Sodium Hydroxide; Swine; Time Factors | 1994 |
Active-site mutations of the diphtheria toxin catalytic domain: role of histidine-21 in nicotinamide adenine dinucleotide binding and ADP-ribosylation of elongation factor 2.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Binding Sites; Calorimetry; Cloning, Molecular; Diphtheria Toxin; Escherichia coli; Genes, Synthetic; Histidine; Hydrogen Bonding; Kinetics; Mutagenesis, Insertional; NAD; NAD+ Nucleosidase; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerases; Recombinant Fusion Proteins; Recombinant Proteins; Restriction Mapping | 1994 |
Regulation of thrombin-induced endothelial cell activation by bacterial toxins.
Topics: Actins; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bacterial Toxins; Botulinum Toxins; Cattle; Cells, Cultured; Cholera Toxin; Cyclic AMP; Endothelium, Vascular; Humans; NAD; Pertussis Toxin; Pulmonary Artery; Thrombin; Umbilical Veins; Virulence Factors, Bordetella | 1994 |
Cysteine-specific ADP-ribosylation of actin.
Topics: Actins; Adenosine Diphosphate Ribose; Binding Sites; Blood Platelets; Cysteine; Electrophoresis, Polyacrylamide Gel; Humans; NAD; Neutrophils; Peptide Mapping; Phosphoric Diester Hydrolases | 1994 |
Cardiac adenylyl cyclase, beta-adrenergic receptors, and G proteins in salt-sensitive hypertension.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Amino Acid Sequence; Animals; Blood Pressure; Cardiomegaly; Cell Membrane; Colforsin; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Hypertension; Immune Sera; Kinetics; Lymphoma; Male; Mice; Molecular Sequence Data; Myocardium; NAD; Oligopeptides; Radioimmunoassay; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Recombinant Proteins; Sodium Chloride; Transducin; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; B-Lymphocytes; Calcium; Cyclic ADP-Ribose; Lymphocyte Activation; Membrane Glycoproteins; Mice; Molecular Sequence Data; N-Glycosyl Hydrolases; NAD; Recombinant Proteins | 1993 |
Human lymphocyte antigen CD38 catalyzes the production of cyclic ADP-ribose.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Catalysis; Cell Line; Chlorocebus aethiops; Cyclic ADP-Ribose; Humans; Membrane Glycoproteins; NAD; Sea Urchins | 1993 |
Correlation between prolactin secretion and Gs protein expression during sustained cholera-toxin stimulation.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cholera Toxin; Cyclic AMP; DNA Probes; Gene Expression; GTP-Binding Proteins; Kinetics; Macromolecular Substances; NAD; Pituitary Neoplasms; Prolactin; Rats; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1993 |
Role of isoprenoid metabolism in chemotactic peptide receptor-mediated G protein activation.
Topics: Adenosine Diphosphate Ribose; Anticholesteremic Agents; Cell Membrane; Cholera Toxin; Granulocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Lovastatin; Macromolecular Substances; N-Formylmethionine Leucyl-Phenylalanine; NAD; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Small GTP-binding proteins of squid photoreceptor. Interaction with photoactivated rhodopsin.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Botulinum Toxins; Cell Membrane; Decapodiformes; GTP-Binding Proteins; Guanosine Triphosphate; Light; Molecular Weight; NAD; Photochemistry; Retina; Rhodopsin; Signal Transduction | 1994 |
Stimulation of endogenous ADP-ribosylation by brefeldin A.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; ADP-Ribosylation Factors; Animals; Biological Transport, Active; Brefeldin A; Cell Line; Cyclopentanes; Glyceraldehyde-3-Phosphate Dehydrogenases; GTP-Binding Proteins; Mycotoxins; NAD; Poly(ADP-ribose) Polymerases; Proteins; Rats; Substrate Specificity | 1994 |
Pertussis toxin-catalyzed ADP-ribosylation of GTP-binding proteins with digoxigenin-conjugated NAD. Identification of the proteins in plasma membranes and nuclei.
Topics: Adenosine Diphosphate Ribose; Animals; Catalysis; Cattle; Cell Membrane; Cell Nucleus; Digoxigenin; GTP-Binding Proteins; HeLa Cells; Humans; NAD; Pertussis Toxin; Virulence Factors, Bordetella | 1994 |
Automodification of arginine-specific ADP-ribosyltransferase purified from chicken peripheral heterophils and alteration of the transferase activity.
Topics: Adenosine Diphosphate Ribose; Animals; Arginine; Chickens; Electrophoresis, Polyacrylamide Gel; Hydroxylamine; Hydroxylamines; Isoenzymes; Kinetics; Leukocytes; Molecular Weight; NAD; Novobiocin; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Substrate Specificity | 1994 |
ADP-ribosylation of neurofilaments by a cytoplasmic ADP-ribose transferase associated with free mRNP.
Topics: Adenosine Diphosphate Ribose; Animals; Blotting, Western; Cations, Divalent; Cattle; Cytosol; Electrophoresis, Polyacrylamide Gel; Intermediate Filaments; Kinetics; Mice; Mice, Inbred BALB C; NAD; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Rats; Ribonucleoproteins; Tumor Cells, Cultured | 1993 |
Nitric oxide-independent, thiol-associated ADP-ribosylation inactivates aldehyde dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Aldehyde Dehydrogenase; Animals; Autoradiography; Brain; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mitochondria; Molecular Weight; NAD; Nitroprusside; Phosphorus Radioisotopes; Rats; Saccharomyces cerevisiae; Substrate Specificity | 1993 |
Glyceraldehyde-3-phosphate dehydrogenase on the surface of group A streptococci is also an ADP-ribosylating enzyme.
Topics: Adenosine Diphosphate Ribose; Antibodies; Blotting, Western; Cytosol; Electrophoresis, Polyacrylamide Gel; Glyceraldehyde-3-Phosphate Dehydrogenases; Membrane Proteins; NAD; Peptide Fragments; Streptococcus pyogenes; Subcellular Fractions; Substrate Specificity | 1993 |
Differential cholera-toxin- and pertussis-toxin-catalysed ADP-ribosylation of G-proteins coupled to formyl-peptide and leukotriene B4 receptors.
Topics: Adenosine Diphosphate Ribose; Cholera Toxin; GTP-Binding Proteins; Guanosine Diphosphate; Guanylyl Imidodiphosphate; Humans; Leukemia, Promyelocytic, Acute; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; NAD; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Leukotriene B4; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Submitochondrial localization of the NAD+ glycohydrolase. Implications for the role of pyridine nucleotide hydrolysis in mitochondrial calcium fluxes.
Topics: Adenosine Diphosphate Ribose; Animals; Biological Transport; Calcium; Hydrolysis; Mitochondria, Liver; NAD; NAD+ Nucleosidase; Pyrimidine Nucleotides; Rats; Submitochondrial Particles | 1993 |
Pertussis toxin treatment increases glutamate release and dihydropyridine binding sites in cultured rat cerebellar granule neurons.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Baclofen; Barium; Binding Sites; Calcium; Calcium Channels; Cells, Cultured; Cerebellum; Cyclic AMP; Dihydropyridines; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamine; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Membrane Potentials; NAD; Neurons; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella | 1993 |
Nicotinamide analogs and DNA-damaging agents deplete thyroid hormone receptor and c-erbA mRNA levels in pituitary GH1 cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; DNA Damage; Enzyme Activation; Gene Expression; NAD; Niacinamide; Pituitary Gland; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Pyridines; Rats; Receptors, Thyroid Hormone; RNA, Messenger | 1993 |
Rapid degradation of NAD by retinoic acid-differentiated HL-60 granulocyte membranes prevents ADP ribosylation.
Topics: Adenosine Diphosphate Ribose; Cell Differentiation; Cell Membrane; Cells, Cultured; Cholera Toxin; Granulocytes; GTP-Binding Proteins; Humans; NAD; NAD+ Nucleosidase; Pertussis Toxin; Tretinoin; Virulence Factors, Bordetella | 1993 |
An NAD derivative produced during transfer RNA splicing: ADP-ribose 1"-2" cyclic phosphate.
Topics: Adenosine Diphosphate Ribose; Animals; Cyclic ADP-Ribose; Endoribonucleases; NAD; Oocytes; Phosphates; Phosphorylation; Phosphotransferases; RNA Splicing; RNA, Fungal; RNA, Transfer; Saccharomyces cerevisiae; Xenopus | 1993 |
Function of NAD glycohydrolase in ADP-ribose uptake from NAD by human erythrocytes.
Topics: Adenosine Diphosphate Ribose; Adult; Aging; Biological Transport; Erythrocytes; Humans; In Vitro Techniques; Infant, Newborn; NAD; NAD+ Nucleosidase | 1993 |
Transfection of NG108-15 cells with antisense opioid-binding cell adhesion molecule cDNA alters opioid receptor-G-protein interaction.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Carrier Proteins; Cell Adhesion Molecules; Cell Membrane; Cholera Toxin; DNA, Antisense; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine-2-Alanine; Glioma; GPI-Linked Proteins; GTP Phosphohydrolases; GTP-Binding Proteins; Hybrid Cells; Kinetics; Membrane Proteins; Mice; Molecular Weight; NAD; Naloxone; Neuroblastoma; Pertussis Toxin; Rats; Receptors, Opioid, delta; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Synthesis and degradation of cyclic ADP-ribose by NAD glycohydrolases.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Dogs; Hydrolysis; Kinetics; NAD; NAD+ Nucleosidase; Spleen | 1993 |
Nitric oxide preferentially stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase compared to alcohol or lactate dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Ethylmaleimide; Glyceraldehyde-3-Phosphate Dehydrogenases; In Vitro Techniques; L-Lactate Dehydrogenase; NAD; Nitric Oxide; Protein Processing, Post-Translational | 1993 |
A biomarker for the assessment of niacin nutriture as a potential preventive factor in carcinogenesis.
Topics: Adenosine Diphosphate Ribose; Biomarkers; Blood Cells; DNA Damage; DNA Repair; Humans; NAD; NADP; Neoplasms; Niacin; Nutritional Status; Polymers | 1993 |
Purification of a nitric oxide-stimulated ADP-ribosylated protein using biotinylated beta-nicotinamide adenine dinucleotide.
Topics: Adenosine Diphosphate Ribose; Animals; Biotin; Brain Chemistry; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; NAD; Nerve Tissue Proteins; Nitric Oxide; Peptide Elongation Factor 2; Peptide Elongation Factors; Rats | 1993 |
Production and hydrolysis of cyclic ADP-ribose at the outer surface of human erythrocytes.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cells, Cultured; Cyclic ADP-Ribose; Erythrocyte Membrane; Humans; Hydrolysis; Membrane Glycoproteins; Microsomes; N-Glycosyl Hydrolases; NAD; Ovum; Sea Urchins | 1993 |
Neuropeptide Y inhibits pertussis toxin-catalyzed ADP-ribosylation in bovine adrenal chromaffin cell membranes.
Topics: Adenosine Diphosphate Ribose; Adrenal Medulla; Animals; Cattle; Cell Membrane; Cells, Cultured; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Membrane Proteins; NAD; Neuropeptide Y; Pertussis Toxin; Virulence Factors, Bordetella | 1993 |
Glyceraldehyde-3-phosphate activates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Aldehydes; Animals; Dithiothreitol; Glyceraldehyde 3-Phosphate; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; Muscles; NAD; Nitroprusside; Rabbits; Substrate Specificity | 1993 |
Molecular characterization of the in vitro activation of pertussis toxin by ATP.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Biotransformation; Blotting, Western; Chromatography, Gel; Chymotrypsin; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Kinetics; Macromolecular Substances; NAD; Peptide Mapping; Pertussis Toxin; Phosphorus Radioisotopes; Recombinant Proteins; Trypsin; Virulence Factors, Bordetella | 1993 |
Wide distribution of an enzyme that catalyzes the hydrolysis of cyclic ADP-ribose.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Brain; Calcium; Chick Embryo; Cyclic ADP-Ribose; Dogs; Hydrogen-Ion Concentration; Models, Chemical; N-Glycosyl Hydrolases; NAD; Niacinamide; Sea Urchins | 1993 |
Regulatory role of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in insulin secretion by glucose in pancreatic beta cells. Enhanced insulin secretion in CD38-expressing transgenic mice.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Cyclic ADP-Ribose; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Membrane Glycoproteins; Mice; Mice, Transgenic; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Potassium Chloride; Promoter Regions, Genetic; Rats; Reference Values; Subcellular Fractions; Tolbutamide | 1995 |
Adenosine diphosphate ribosylation of fibroblast growth factor-2.
Topics: Adenocarcinoma; Adenosine Diphosphate Ribose; Cell Line; Cell Nucleus; Endothelium, Vascular; Fibroblast Growth Factor 2; Glycosylation; Growth Substances; Liver Neoplasms; NAD; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Substrate Specificity; Tumor Cells, Cultured | 1995 |
Analysis of the catalytic site of the actin ADP-ribosylating Clostridium perfringens iota toxin.
Topics: Actins; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Affinity Labels; Amino Acid Sequence; Bacterial Toxins; Binding Sites; Catalysis; Clostridium perfringens; Cyanogen Bromide; Glutamic Acid; Molecular Sequence Data; NAD; Peptide Fragments; Photochemistry; Ultraviolet Rays | 1996 |
Regulation of CTL by ecto-nictinamide adenine dinucleotide (NAD) involves ADP-ribosylation of a p56lck-associated protein.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; CD8-Positive T-Lymphocytes; Cytotoxicity, Immunologic; Down-Regulation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Weight; NAD; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Receptors, Antigen, T-Cell; Signal Transduction; src-Family Kinases; T-Lymphocytes, Cytotoxic | 1996 |
ADP-ribosylation of an approximately 70-kilodalton protein of Klebsiella pneumoniae.
Topics: Adenosine Diphosphate Ribose; Animals; Bacterial Proteins; Blood Platelets; Brain; Dithiothreitol; Humans; In Vitro Techniques; Klebsiella pneumoniae; Lung; Molecular Weight; NAD; Neutrophils; Rats; Spleen; Sulfhydryl Reagents | 1996 |
G-protein regulation of outwardly rectified epithelial chloride channels incorporated into planar bilayer membranes.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Cattle; Cell Membrane; Chloride Channels; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Lipid Bilayers; Membrane Potentials; NAD; Pertussis Toxin; Phosphorylation; Trachea; Virulence Factors, Bordetella | 1996 |
Mouse T cell membrane proteins Rt6-1 and Rt6-2 are arginine/protein mono(ADPribosyl)transferases and share secondary structure motifs with ADP-ribosylating bacterial toxins.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Animals; Antigens, Differentiation, T-Lymphocyte; Arginine; Bacterial Toxins; Base Sequence; Cell Membrane; Chickens; Chromatography, Affinity; Cloning, Molecular; Conserved Sequence; DNA Primers; Histocompatibility Antigens; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Sequence Data; NAD; Poly(ADP-ribose) Polymerases; Polymerase Chain Reaction; Protein Structure, Secondary; Recombinant Proteins; Sequence Homology, Amino Acid; Sequence Tagged Sites; Spleen; T-Lymphocytes; Transfection | 1996 |
Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cyclic ADP-Ribose; Cyclic GMP; Enzyme Inhibitors; Female; Guanosine Triphosphate; Isomerism; Kinetics; Mammals; Models, Biological; N-Glycosyl Hydrolases; NAD; Niacinamide; Nitric Oxide; Ovum; Sea Urchins; Signal Transduction; Thionucleotides; Time Factors | 1996 |
Rat RT6.2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antigens, Differentiation, T-Lymphocyte; Base Sequence; Cross-Linking Reagents; DNA Primers; Female; Histocompatibility Antigens; In Vitro Techniques; Lymphocyte Activation; Male; Membrane Glycoproteins; Mice; Molecular Sequence Data; NAD; Rats; Rats, Inbred BB; Rats, Inbred WF; Recombinant Proteins; T-Lymphocytes | 1996 |
Inhibition of cADPR-Hydrolase by ADP-ribose potentiates cADPR synthesis from beta-NAD+.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cyclic ADP-Ribose; Enzyme Inhibitors; Female; Kinetics; Microsomes; N-Glycosyl Hydrolases; NAD; Ovum; Sea Urchins | 1996 |
Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bacterial Toxins; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Exotoxins; Models, Molecular; NAD; Poly(ADP-ribose) Polymerases; Protein Conformation; Protein Structure, Secondary; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Recombinant Proteins; Thiazoles; Virulence Factors | 1996 |
ADP-ribosylation of wild-type p53 in vitro: binding of p53 protein to specific p53 consensus sequence prevents its modification.
Topics: Adenosine Diphosphate Ribose; Animals; Cells, Cultured; Consensus Sequence; Embryo, Mammalian; Embryo, Nonmammalian; Humans; Mice; NAD; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred F344; Recombinant Proteins; Spodoptera; Substrate Specificity; Transfection; Tumor Suppressor Protein p53 | 1996 |
Enzymatic activities affecting exogenous nicotinamide adenine dinucleotide in human skin fibroblasts.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Cells, Cultured; Chromatography, High Pressure Liquid; Enzymes; Fibroblasts; Humans; NAD; Skin | 1996 |
Insulin exocytosis and glucose-mediated increase in cytoplasmic free Ca2+ concentration in the pancreatic beta-cell are independent of cyclic ADP-ribose.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Cytoplasm; Exocytosis; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Mice; Mice, Obese; NAD | 1996 |
Characterization of adenylyl cyclase stimulated by VIP in rat and mouse peritoneal macrophage membranes.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Intercellular Signaling Peptides and Proteins; Kinetics; Macrophages, Peritoneal; Mice; NAD; Neuropeptides; Peptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Secretin; Sodium Fluoride; Vasoactive Intestinal Peptide | 1996 |
Effect of pertussis toxin and B-oligomer on platelet-activating factor-induced generation of inositol phosphates in porcine alveolar macrophages.
Topics: Adenosine Diphosphate Ribose; Aluminum Chloride; Aluminum Compounds; Analysis of Variance; Animals; Azepines; Bronchoalveolar Lavage; Cell Survival; Cells, Cultured; Chlorides; GTP-Binding Proteins; Inositol; Inositol Phosphates; L-Lactate Dehydrogenase; Macrophages, Alveolar; NAD; Pertussis Toxin; Platelet Activating Factor; Platelet Aggregation Inhibitors; Random Allocation; Sodium Fluoride; Swine; Triazoles; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
ADP-ribosylation of proteins in Bacillus subtilis and its possible importance in sporulation.
Topics: Adenosine Diphosphate Ribose; Bacillus subtilis; Bacterial Proteins; Benzamides; Drug Resistance, Microbial; Enzyme Inhibitors; Kinetics; Molecular Weight; Mutagenesis; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Spores, Bacterial | 1996 |
Intracellular ADP-ribose inhibits ATP-sensitive K+ channels in rat ventricular myocytes.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Cyclic ADP-Ribose; Heart Ventricles; Intracellular Membranes; Myocardium; NAD; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley | 1996 |
Mechanism of cyclization of pyridine nucleotides by bovine spleen NAD+ glycohydrolase.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cyclic ADP-Ribose; Guanosine Diphosphate Sugars; NAD; NAD+ Nucleosidase; Spleen; Substrate Specificity | 1996 |
Evidence for endogenous ADP-ribosylation of GTP-binding proteins in neuronal cell nucleus. Possible induction by membrane depolarization.
Topics: Adenosine Diphosphate Ribose; Animals; Batrachotoxins; Brain; Brain Stem; Cell Nucleus; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Male; Membrane Potentials; Mice; NAD; Neurons; Pertussis Toxin; Potassium; Rats; Signal Transduction; Virulence Factors, Bordetella | 1996 |
Endogenous ADP-ribosylation of proteins in Mycobacterium smegmatis.
Topics: Adenosine Diphosphate Ribose; Bacterial Proteins; Mycobacterium; NAD; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational | 1996 |
Regulation of NAD+ glycohydrolase activity by NAD(+)-dependent auto-ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Animals; Binding Sites; Cysteine; Erythrocytes; In Vitro Techniques; Kinetics; Molecular Weight; NAD; NAD+ Nucleosidase; Rabbits | 1996 |
Rat liver mitochondria can synthesize nicotinamide adenine dinucleotide from nicotinamide mononucleotide and ATP via a putative matrix nicotinamide mononucleotide adenylyltransferase.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Diphosphates; Hydrogen-Ion Concentration; Male; Mitochondria, Liver; NAD; NADP; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Rats; Substrate Specificity | 1996 |
Characterization of ADP-ribosylation sites on desmin and restoration of desmin intermediate filament assembly by de-ADP-ribosylation .
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Animals; Brain; Chromatography, High Pressure Liquid; Desmin; Intermediate Filaments; Kinetics; Microscopy, Electron; Molecular Sequence Data; NAD; Peptide Fragments; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 1996 |
NAD+-dependent internalization of the transmembrane glycoprotein CD38 in human Namalwa B cells.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; B-Lymphocytes; Cell Membrane; Cyclic ADP-Ribose; Down-Regulation; Endocytosis; Glutathione; Humans; Membrane Glycoproteins; Microscopy, Fluorescence; Microscopy, Immunoelectron; N-Glycosyl Hydrolases; NAD; Organelles; Tumor Cells, Cultured | 1996 |
Direct thyroid hormone signalling via ADP-ribosylation controls mitochondrial nucleotide transport and membrane leakiness by changing the conformation of the adenine nucleotide transporter.
Topics: Adenine Nucleotides; Adenosine Diphosphate Ribose; Allosteric Regulation; Animals; Calcium; Electrophoresis, Polyacrylamide Gel; Hypothyroidism; Intracellular Membranes; Male; Membrane Proteins; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; NAD; Niacinamide; Permeability; Poly(ADP-ribose) Polymerases; Protein Conformation; Rats; Rats, Sprague-Dawley; Triiodothyronine | 1996 |
NAD+ analogs substituted in the purine base as substrates for poly(ADP-ribosyl) transferase.
Topics: Adenosine Diphosphate Ribose; Catalysis; Guanine Nucleotides; NAD; NAD+ Nucleosidase; Phosphodiesterase I; Phosphoric Diester Hydrolases; Poly(ADP-ribose) Polymerases; Polymers; Recombinant Proteins; Structure-Activity Relationship | 1996 |
Cholera and pertussis toxins reveal multiple regulation of cAMP levels in the rabbit carotid body.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Calcium; Carotid Body; Cell Membrane; Cholera Toxin; Cyclic AMP; GTP-Binding Proteins; Hypoxia; In Vitro Techniques; Kinetics; NAD; Nerve Tissue Proteins; Pertussis Toxin; Rabbits; Virulence Factors, Bordetella | 1996 |
Characterization of heterotrimeric G-proteins in adult Acanthocheilonema viteae.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Antibodies; Blotting, Western; Cholera Toxin; Dipetalonema; DNA Primers; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Macromolecular Substances; Molecular Sequence Data; NAD; Peptide Fragments; Pertussis Toxin; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Virulence Factors, Bordetella | 1996 |
ADP-ribosylation of serum proteins: evaluation as a potential tumor marker.
Topics: Adenosine Diphosphate Ribose; Adult; Aged; Biomarkers, Tumor; Blood Proteins; Carcinoembryonic Antigen; Female; Humans; Male; Middle Aged; NAD; Neoplasms | 1996 |
The alpha2-adrenergic receptor is more effective than the galanin receptor in activating G-proteins in RINm5F beta-cell membranes.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Cholera Toxin; Clonidine; Galanin; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Islets of Langerhans; Kinetics; NAD; Norepinephrine; Receptors, Adrenergic, alpha-2; Receptors, Galanin; Receptors, Gastrointestinal Hormone | 1997 |
Overexpression of human poly(ADP-ribose) polymerase in transfected hamster cells leads to increased poly(ADP-ribosyl)ation and cellular sensitization to gamma irradiation.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Cell Survival; CHO Cells; Cricetinae; Gamma Rays; Humans; NAD; Poly(ADP-ribose) Polymerases; Transfection | 1997 |
Analysis of poly(ADP-ribose) glycohydrolase activity in nuclear extracts from mammalian cells.
Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Cell Nucleus; CHO Cells; Chromatography, Thin Layer; Cricetinae; Ethacridine; Etoposide; Glycoside Hydrolases; HeLa Cells; HL-60 Cells; Humans; Kinetics; NAD; Neuroblastoma; Phosphorus Radioisotopes; Tumor Cells, Cultured | 1997 |
NAD-dependent cross-linking of dinitrogenase reductase and dinitrogenase reductase ADP-ribosyltransferase from Rhodospirillum rubrum.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP Ribose Transferases; Amino Acid Sequence; Catalysis; Cross-Linking Reagents; Dinitrogenase Reductase; Molecular Sequence Data; NAD; Rhodospirillum rubrum; Sodium Chloride | 1997 |
Effect of estrogen upon cyclic ADP ribose metabolism: beta-estradiol stimulates ADP ribosyl cyclase in rat uterus.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Brain; Calcium; Cell Nucleus; Chromatography, High Pressure Liquid; Cyclic ADP-Ribose; Estradiol; Female; Kidney; Kinetics; Liver; Membrane Glycoproteins; Models, Biological; Muscle, Smooth; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Ovariectomy; Ovum; Parathyroidectomy; Rats; Rats, Sprague-Dawley; Receptors, Estradiol; Sea Urchins; Second Messenger Systems; Tamoxifen; Thyroidectomy; Uterus | 1997 |
Activation of Ca2+-dependent currents in dorsal root ganglion neurons by metabotropic glutamate receptors and cyclic ADP-ribose precursors.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cells, Cultured; Cyclic ADP-Ribose; Cyclic GMP; Ganglia, Spinal; Glutamic Acid; Membrane Potentials; Muscle Proteins; NAD; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Ryanodine Receptor Calcium Release Channel; Synaptic Transmission | 1997 |
Sarcoplasmic reticulum-associated and protein kinase C-regulated ADP-ribosyl cyclase in cardiac muscle.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Cyclic ADP-Ribose; Dithiothreitol; Dogs; Electrophoresis, Polyacrylamide Gel; Guanine Nucleotides; Guanosine Diphosphate Sugars; Isoenzymes; Membrane Glycoproteins; Myocardium; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Phosphorylation; Protein Kinase C; Rats; Sarcoplasmic Reticulum | 1997 |
ADP-ribosylation of serum proteins: elevated levels in neoplastic cases due to altered NAD/ADP-ribose metabolism.
Topics: Adenosine Diphosphate Ribose; Adolescent; Adult; Age Factors; Aged; Animals; Biomarkers; Blood Proteins; Brain; Child; Child, Preschool; Disease; Female; Humans; Infant; Kinetics; Male; Middle Aged; NAD; NAD+ Nucleosidase; Neoplasms; Reference Values; Regression Analysis; Sex Characteristics; Swine | 1997 |
Residues within the polycationic region of cGMP phosphodiesterase gamma subunit crucial for the interaction with transducin alpha subunit. Identification by endogenous ADP-ribosylation and site-directed mutagenesis.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Animals; Arginine; Binding Sites; Cattle; Cyclic Nucleotide Phosphodiesterases, Type 6; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Mutagenesis, Site-Directed; NAD; Pertussis Toxin; Rana catesbeiana; Recombinant Proteins; Transducin; Virulence Factors, Bordetella | 1997 |
Mouse RT6 locus 1 and rat RT6.2 are NAD+. Arginine ADP-ribosyltransferases with auto-ADP-ribosylation activity.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antigens, Differentiation, T-Lymphocyte; Catalysis; Cell Division; Cell Line; Genetic Linkage; Histocompatibility Antigens; Membrane Glycoproteins; Mice; NAD; Precipitin Tests; Rats; Recombinant Fusion Proteins; Spodoptera; T-Lymphocytes | 1997 |
An ADP-ribosyltransferase from bovine erythrocytes apparently specific for cysteine residues.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cysteine; Enzyme Inhibitors; Erythrocytes; Ethylmaleimide; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases; Substrate Specificity | 1997 |
Endogenous mono-ADP-ribosylation in retina and peripheral nervous system. Effects of diabetes.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Diabetes Mellitus, Experimental; Insulin; NAD; Peripheral Nervous System; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Retina; Silymarin; Superior Cervical Ganglion | 1997 |
Metabolism and actions of ADP-riboses in coronary arterial smooth muscle.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Coronary Vessels; Cyclic ADP-Ribose; Electrophysiology; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Muscle, Smooth, Vascular; NAD; Potassium Channels; Potassium Channels, Calcium-Activated; Vasodilator Agents | 1997 |
Bovine liver mitochondrial NAD+ glycohydrolase. Relationship to ADP-ribosylation and calcium fluxes.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Calcium; Cattle; Dithiothreitol; Edetic Acid; Enzyme Inhibitors; Guanosine Diphosphate Sugars; Magnesium Chloride; Mitochondria, Liver; NAD; NAD+ Nucleosidase | 1997 |
Protein-protein interaction of the human poly(ADP-ribosyl)transferase depends on the functional state of the enzyme.
Topics: Adenosine Diphosphate Ribose; beta-Galactosidase; Binding Sites; DNA; Gene Deletion; HeLa Cells; Histidine; Histones; Humans; NAD; Poly(ADP-ribose) Polymerases; Protein Binding; Recombinant Fusion Proteins; Sodium Chloride; Zinc Fingers | 1997 |
Pertussis toxin: transition state analysis for ADP-ribosylation of G-protein peptide alphai3C20.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Catalysis; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Deuterium; GTP-Binding Proteins; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; NAD; Pertussis Toxin; Protein Structure, Secondary; Ribose; Virulence Factors, Bordetella | 1997 |
Endogenous ADP-ribosylation of a G(alpha i) protein in bovine ciliary body is stimulated by nitric oxide.
Topics: Adenosine Diphosphate Ribose; Animals; Blotting, Western; Cattle; Cell Membrane; Ciliary Body; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Hydroxylamine; Hydroxylamines; Kinetics; Macromolecular Substances; Membrane Proteins; Mercury; Molecular Weight; NAD; Nitric Oxide; Nitrogen Oxides; Phosphorus Radioisotopes; Spermine | 1997 |
Use of biotinylated NAD to label and purify ADP-ribosylated proteins.
Topics: Adenosine Diphosphate Ribose; Biotin; Chromatography, Affinity; Glyceraldehyde-3-Phosphate Dehydrogenases; GTP-Binding Proteins; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Proteins | 1997 |
Preparation of cyclic ADP-ribose, 2'-phospho-cyclic ADP-ribose, and nicotinate adenine dinucleotide phosphate: possible second messengers of calcium signaling.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Aplysia; Calcium; Cyclic ADP-Ribose; Cyclic AMP; Enzymes, Immobilized; Lyases; N-Glycosyl Hydrolases; NAD; NADP; Nucleotides, Cyclic; Second Messenger Systems | 1997 |
ADPribosylation reaction by free ADPribose in Sulfolobus solfataricus, a thermophilic archaeon.
Topics: Adenosine Diphosphate Ribose; Bacterial Proteins; Enzyme Inhibitors; Hydrogen-Ion Concentration; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Sulfolobus | 1997 |
Detection and identification of NAD-catabolizing activities in rat tissue homogenates.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Detergents; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Kidney Cortex; Male; Molecular Weight; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Pyrophosphatases; Rats; Rats, Wistar; Spleen; Zinc | 1997 |
A competitive inhibition of the mitochondrial NADH-ubiquinone oxidoreductase (complex I) by ADP-ribose.
Topics: Adenosine Diphosphate Ribose; Animals; Binding Sites; Binding, Competitive; Cattle; Chromatography, DEAE-Cellulose; Electron Transport Complex I; Enzyme Inhibitors; Flavoproteins; Kinetics; Myocardium; NAD; NAD+ Nucleosidase; NADH, NADPH Oxidoreductases; Spectrophotometry; Submitochondrial Particles; Succinates; Succinic Acid | 1997 |
Roles for adenosine ribose hydroxyl groups in cyclic adenosine 5'-diphosphate ribose-mediated Ca2+ release.
Topics: Adenosine Diphosphate Ribose; Animals; Aplysia; Calcium; Cyclic ADP-Ribose; Hydrogen Bonding; Hydroxyl Radical; NAD; Sea Urchins; Spectrum Analysis; Structure-Activity Relationship | 1997 |
ADP-ribosylation of tuftsin suppresses its receptor-binding capacity and phagocytosis-stimulating activity to murine peritoneal macrophages.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Calcimycin; Calcium; Chickens; Chromatography, High Pressure Liquid; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; NAD; Opsonin Proteins; Phagocytosis; Receptors, Immunologic; Tuftsin; Zymosan | 1997 |
Fourier transform infrared spectroscopic studies of proton transfer processes and the dissociation of Zn2+-bound water in alcohol dehydrogenases.
Topics: Adenine; Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Animals; Histidine; Horses; Hydrogen Bonding; Liver; NAD; Protons; Saccharomyces cerevisiae; Spectroscopy, Fourier Transform Infrared; Trifluoroethanol; Water; Zinc | 1997 |
cADP-ribose releases Ca2+ from cardiac sarcoplasmic reticulum independently of ryanodine receptor.
Topics: Adenosine Diphosphate Ribose; Aniline Compounds; Animals; Calcimycin; Calcium; Calcium Channel Agonists; Calcium Channels; Carbolines; Cyclic ADP-Ribose; Dogs; Drug Synergism; Fluorescent Dyes; Kinetics; Microsomes; Models, Cardiovascular; Muscle Proteins; Myocardium; NAD; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Xanthenes | 1997 |
Purification of bovine soluble guanylate cyclase and ADP-ribosylation on its small subunit by bacterial toxins.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Animals; Bacterial Toxins; Cattle; Cyclic GMP; Guanosine Triphosphate; Guanylate Cyclase; Heme; Kinetics; Lung; Macromolecular Substances; Manganese; NAD; Nitric Oxide; Sensitivity and Specificity; Solubility | 1997 |
GTP-dependent modification of a 21-kDa substrate with NAD+ in bovine brain soluble fraction is not ADP-ribosylation of small G-protein but tailing of tRNA.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Botulinum Toxins; Brain; Cattle; GTP-Binding Proteins; Guanosine Triphosphate; Molecular Weight; NAD; Phosphorus Radioisotopes; RNA, Transfer; Subcellular Fractions; Substrate Specificity | 1997 |
Nitric oxide-induced modification of glyceraldehyde-3-phosphate dehydrogenase with NAD+ is not ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Animals; Catalysis; Cattle; Glyceraldehyde-3-Phosphate Dehydrogenases; NAD; Nitric Oxide; Phosphorus Radioisotopes | 1997 |
Specificity and target proteins of arginine-specific mono-ADP-ribosylation in T-tubules of rabbit skeletal muscle.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Arginine; Biotin; Carbon Radioisotopes; Digoxigenin; GTP-Binding Protein alpha Subunits, Gs; Muscle Proteins; Muscle, Skeletal; NAD; Phosphorus Radioisotopes; Rabbits | 1997 |
Role of NAD+ and ADP-ribosylation in the maintenance of the Golgi structure.
Topics: Adenosine Diphosphate Ribose; Animals; Brefeldin A; Cell Membrane Permeability; Coatomer Protein; Cyclopentanes; Endoplasmic Reticulum; Golgi Apparatus; Membrane Proteins; NAD; Rats; Tumor Cells, Cultured | 1997 |
Thio-NADP is not an antagonist of NAADP.
Topics: Adenosine Diphosphate Ribose; Animals; Anion Exchange Resins; Calcium; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cyclic ADP-Ribose; Drug Contamination; NAD; NADP; Oocytes; Resins, Synthetic; Sea Urchins | 1998 |
Muscarinic receptor-mediated dual regulation of ADP-ribosyl cyclase in NG108-15 neuronal cell membranes.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Cell Line; Cell Membrane; Chromatography, Thin Layer; COS Cells; Cyclic ADP-Ribose; Humans; Membrane Glycoproteins; Multienzyme Complexes; NAD; NAD+ Nucleosidase; Neurons; Receptors, Muscarinic; Transfection | 1997 |
Helicobacter pylori extracts exhibit nicotinamide adenine dinucleotide-derived adenylation but not mono(adenosine 5'-diphosphate-ribosyl)ation of DNA ligase.
Topics: Adenosine Diphosphate Ribose; Bacterial Proteins; DNA Ligases; Electrophoresis, Polyacrylamide Gel; Helicobacter pylori; Hydrochloric Acid; NAD; Nucleoside Diphosphate Sugars; Precipitin Tests; Ribonucleosides; Single-Strand Specific DNA and RNA Endonucleases; Sodium Hydroxide; Thermolysin | 1997 |
Analysis of the combined effect of two linear inhibitors on a single enzyme.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Animals; Binding, Competitive; Drug Synergism; Enzyme Inhibitors; Horses; Liver; Models, Chemical; NAD; Phenanthrolines | 1998 |
Orf186 represents a new member of the Nudix hydrolases, active on adenosine(5')triphospho(5')adenosine, ADP-ribose, and NADH.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Cloning, Molecular; Dinucleoside Phosphates; Humans; Hydrolases; Molecular Sequence Data; NAD; Nudix Hydrolases; Pyrophosphatases; Sequence Homology, Amino Acid; Substrate Specificity | 1998 |
Transition-state structure for the ADP-ribosylation of recombinant Gialpha1 subunits by pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Catalysis; GTP-Binding Protein alpha Subunits, Gi-Go; Hydrolysis; Kinetics; Models, Chemical; Models, Molecular; NAD; Pertussis Toxin; Virulence Factors, Bordetella | 1998 |
Cyclic ADP-ribose and calcium-induced calcium release regulate neurotransmitter release at a cholinergic synapse of Aplysia.
Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Aplysia; Calcium; Cyclic ADP-Ribose; Electrophysiology; Fluorescent Dyes; Ganglia, Invertebrate; Membrane Potentials; NAD; Neurotransmitter Agents; Parasympathetic Nervous System; Patch-Clamp Techniques; Polymerase Chain Reaction; Receptors, Presynaptic; Ryanodine Receptor Calcium Release Channel; Synapses | 1998 |
Differential regulation of nicotinic acid-adenine dinucleotide phosphate and cADP-ribose production by cAMP and cGMP.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Cyclic AMP; Cyclic GMP; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Niacin; Oocytes; Sea Urchins; Second Messenger Systems; Temperature | 1998 |
The mechanism of the elongation and branching reaction of poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis.
Topics: Adenosine Diphosphate Ribose; Animals; Binding Sites; Chickens; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Models, Molecular; Mutagenesis; NAD; Niacinamide; Peptide Fragments; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship | 1998 |
Enzymic, cysteine-specific ADP-ribosylation in bovine liver mitochondria.
Topics: Adenosine Diphosphate Ribose; Aldehyde Dehydrogenase; Animals; Cattle; Cysteine; Disulfides; Enzyme Inhibitors; Ethylmaleimide; Fungal Proteins; Mitochondria, Liver; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases | 1998 |
Calcium signaling by cyclic ADP-ribose, NAADP, and inositol trisphosphate are involved in distinct functions in ascidian oocytes.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Chelating Agents; Cyclic ADP-Ribose; Electrophysiology; Fertilization; Inositol 1,4,5-Trisphosphate; NAD; NAD+ Nucleosidase; NADP; Oocytes; Patch-Clamp Techniques; Ryanodine; Signal Transduction; Urochordata | 1998 |
A role for NAD+ and cADP-ribose in melatonin signal transduction.
Topics: Adenosine Diphosphate Ribose; Cyclic ADP-Ribose; Humans; Melanoma; Melatonin; NAD; Signal Transduction; Tumor Cells, Cultured | 1998 |
Pertussis toxin abolishes the cardioprotective effect of ischemic preconditioning in intact rat heart.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate Ribose; Animals; Dogs; GTP-Binding Proteins; Heart Rate; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; NAD; Pertussis Toxin; Rabbits; Rats; Rats, Wistar; Virulence Factors, Bordetella | 1998 |
Regulation of KCa-channel activity by cyclic ADP-ribose and ADP-ribose in coronary arterial smooth muscle.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; Animals; Calcium; Cattle; Chromatography, High Pressure Liquid; Coronary Vessels; Cyclic ADP-Ribose; Cytosol; Electric Conductivity; Kinetics; Membrane Potentials; Microsomes; Muscle, Smooth, Vascular; NAD; NAD+ Nucleosidase; Phosphorus-Oxygen Lyases; Potassium Channels | 1998 |
The reaction mechanism for CD38. A single intermediate is responsible for cyclization, hydrolysis, and base-exchange chemistries.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Binding, Competitive; Catalysis; Cyclic ADP-Ribose; Fluorescence Polarization; Guanosine Diphosphate Sugars; Humans; Hydrolysis; Kinetics; Membrane Glycoproteins; Methanol; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Spectrometry, Fluorescence; Substrate Specificity | 1998 |
A novel deamido-NAD+-binding site revealed by the trapped NAD-adenylate intermediate in the NAD+ synthetase structure.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Amide Synthases; Bacillus subtilis; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cyclic ADP-Ribose; Models, Molecular; Molecular Sequence Data; NAD; Protein Conformation | 1998 |
Auto-ADP-ribosylation of NAD glycohydrolase from Neurospora crassa.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Enzyme Inhibitors; Fungal Proteins; NAD; NAD+ Nucleosidase; Neurospora crassa; Phosphoric Diester Hydrolases | 1998 |
The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranes.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Biological Transport; Catalysis; Cyclic ADP-Ribose; Erythrocyte Membrane; Guanosine Diphosphate Sugars; HeLa Cells; Humans; Membrane Glycoproteins; NAD; NAD+ Nucleosidase; Proteolipids; Second Messenger Systems | 1998 |
ADP-ribose gates the fertilization channel in ascidian oocytes.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cell Membrane Permeability; Chelating Agents; Ciona intestinalis; Egtazic Acid; Electric Conductivity; Female; Fertilization; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Potentials; NAD; NADP; Niacinamide; Oocytes; Patch-Clamp Techniques; Sodium | 1998 |
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Ankyrins; Benzamides; Catalytic Domain; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Humans; Molecular Sequence Data; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Structure, Secondary; Recombinant Proteins; Repetitive Sequences, Amino Acid; Sequence Alignment; Sequence Homology, Amino Acid; Tankyrases; Telomere; Telomeric Repeat Binding Protein 1 | 1998 |
Effect of NADH-X on cytosolic glycerol-3-phosphate dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Animals; Chromatography, High Pressure Liquid; Cytosol; Dialysis; Enzyme Activation; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerol-3-Phosphate Dehydrogenase (NAD+); Glycerolphosphate Dehydrogenase; Hydrogen-Ion Concentration; Islets of Langerhans; Kinetics; Ligands; Liver; Muscle, Skeletal; NAD; NADP; Oxidation-Reduction; Rabbits; Rats | 1998 |
Involvement of cytosolic NAD+ glycohydrolase in cyclic ADP-ribose metabolism.
Topics: Adenosine Diphosphate Ribose; Allosteric Site; Animals; Brain; Cattle; Cyclic ADP-Ribose; Cytosol; Enzyme Activation; Hydrolysis; Kinetics; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Substrate Specificity | 1998 |
Transient ADP-ribosylation of a 2'-phosphate implicated in its removal from ligated tRNA during splicing in yeast.
Topics: Adenosine Diphosphate Ribose; Animals; Cyclic ADP-Ribose; Escherichia coli; Escherichia coli Proteins; Mice; NAD; Phosphotransferases (Alcohol Group Acceptor); RNA Splicing; RNA, Transfer; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Tumor Protein, Translationally-Controlled 1 | 1999 |
Ligand-induced internalization of CD38 results in intracellular Ca2+ mobilization: role of NAD+ transport across cell membranes.
Topics: 3T3 Cells; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Biological Transport; Calcium; HeLa Cells; Humans; Jurkat Cells; Ligands; Membrane Glycoproteins; Mice; NAD; NAD+ Nucleosidase; Second Messenger Systems; Signal Transduction | 1999 |
CD38 signaling in B lymphocytes is controlled by its ectodomain but occurs independently of enzymatically generated ADP-ribose or cyclic ADP-ribose.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Antigens, CD; B-Lymphocytes; CD48 Antigen; Cyclic ADP-Ribose; Mice; Molecular Sequence Data; NAD; Rabbits; Signal Transduction; Transfection | 1999 |
Biochemical characterization of mono(ADP-ribosyl)ated poly(ADP-ribose) polymerase.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Catalysis; Cattle; Chromatin; Chymotrypsin; Hydrolysis; Liver; NAD; Papain; Poly(ADP-ribose) Polymerases; Rats; Substrate Specificity | 1999 |
Role of brefeldin A-dependent ADP-ribosylation in the control of intracellular membrane transport.
Topics: Adenosine Diphosphate Ribose; Angiotensin-Converting Enzyme Inhibitors; Animals; Brefeldin A; Carrier Proteins; Cytosol; Dose-Response Relationship, Drug; Glyceraldehyde-3-Phosphate Dehydrogenases; Golgi Apparatus; Inhibitory Concentration 50; Leukemia; Microscopy, Fluorescence; NAD; Peptide Fragments; Protein Synthesis Inhibitors; Rats; Time Factors; Tissue Distribution; Tumor Cells, Cultured | 1999 |
Membrane association of a new inositol 1,4,5-trisphosphate binding protein, p130 is not dependent on the pleckstrin homology domain.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Calcium Channels; Cell Membrane; COS Cells; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Fragments; Rats; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; src Homology Domains; Transfection | 1999 |
Characterization of alpha(s)-immunoreactive ADP-ribosylated proteins in postmortem human brain.
Topics: Adenosine Diphosphate Ribose; Adult; Aged; Aged, 80 and over; Autopsy; Autoradiography; Brain; Cholera Toxin; Dithiothreitol; Female; GTP-Binding Protein alpha Subunits, Gs; Humans; Kinetics; Male; Middle Aged; NAD; Peptide Mapping; Phosphorus Radioisotopes; Temporal Lobe | 1999 |
Inhibition of high glucose-induced protein mono-ADP-ribosylation restores neuritogenesis and sodium-pump activity in SY5Y neuroblastoma cells.
Topics: Adenosine Diphosphate Ribose; Culture Media, Serum-Free; Diabetes Mellitus; Glucose; Humans; Kinetics; NAD; Neurites; Neuroblastoma; Sodium-Potassium-Exchanging ATPase; Tretinoin; Tumor Cells, Cultured | 1999 |
CD38/ADP-ribosyl cyclase: A new role in the regulation of osteoclastic bone resorption.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Animals; Animals, Newborn; Antigens, CD; Antigens, Differentiation; Base Sequence; Bone Resorption; Calcium Signaling; Cell Membrane; Cells, Cultured; Cloning, Molecular; Cyclic ADP-Ribose; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Interleukin-6; Membrane Glycoproteins; Molecular Sequence Data; NAD; NAD+ Nucleosidase; Osteoclasts; Rabbits; Rats; Rats, Wistar; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Sequence Homology, Amino Acid | 1999 |
Molecular cloning of an apoptosis-inducing protein, pierisin, from cabbage butterfly: possible involvement of ADP-ribosylation in its activity.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Binding Sites; Butterflies; Cell Line; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; HeLa Cells; Humans; Insect Proteins; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Sequence Homology, Amino Acid | 1999 |
Modification of the ADP-ribosyltransferase and NAD glycohydrolase activities of a mammalian transferase (ADP-ribosyltransferase 5) by auto-ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Electrophoresis, Polyacrylamide Gel; Kinetics; NAD; NAD+ Nucleosidase; Oligopeptides; Pentosyltransferases; Peptides; Poly(ADP-ribose) Polymerases; Rabbits | 1999 |
Synthesis of NAADP and cADPR in mitochondria.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Cell Compartmentation; Cell Membrane; Cyclic ADP-Ribose; Dithiothreitol; Glycosylphosphatidylinositols; Guanine Nucleotides; Isoenzymes; Membrane Glycoproteins; Mitochondria, Liver; Multienzyme Complexes; NAD; NAD+ Nucleosidase; NADP; Niacinamide; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Rats; Rats, Sprague-Dawley; Type C Phospholipases | 1999 |
Arylazido-beta-alanine ADP-ribose, a novel irreversible competitive inhibitor of mitochondrial NADH-ubiquinone reductase.
Topics: Adenosine Diphosphate Ribose; Animals; Azides; Binding Sites; Cattle; Electron Transport Complex I; Enzyme Inhibitors; Kinetics; Mitochondria, Heart; NAD; NAD+ Nucleosidase; NADH, NADPH Oxidoreductases; Photolysis | 1999 |
A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasis.
Topics: 3T3 Cells; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Cell Fractionation; Cell Nucleus; Cyclic ADP-Ribose; Genes, Reporter; Immunoblotting; Inositol 1,4,5-Trisphosphate; Membrane Glycoproteins; Mice; Microscopy, Confocal; Multienzyme Complexes; NAD; NAD+ Nucleosidase; Nuclear Envelope; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel | 1999 |
Enhanced ADP-ribosylation and its diminution by lipoamide after ischemia-reperfusion in perfused rat heart.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antioxidants; DNA Damage; Enzyme Activation; In Vitro Techniques; Lipid Peroxidation; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; NAD; Perfusion; Poly(ADP-ribose) Polymerases; Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Thioctic Acid | 1999 |
ADP-ribosylation of tubulin by chicken NAD-arginine ADP-ribosyltransferase suppresses microtubule formation.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Brain; Cattle; Chickens; Cytosol; Electrophoresis, Polyacrylamide Gel; Kinetics; Microtubules; NAD; Neutrophils; Tubulin | 1999 |
cADP-ribose potentiates cytosolic Ca2+ elevation and Ca2+ entry via L-type voltage-activated Ca2+ channels in NG108-15 neuronal cells.
Topics: Adenosine Diphosphate Ribose; Biological Transport; Calcium; Calcium Channels, L-Type; Cells, Cultured; Cyclic ADP-Ribose; Cytosol; Ion Channel Gating; Manganese; Membrane Potentials; Models, Biological; NAD; Neurons; Niacinamide; Nifedipine; Patch-Clamp Techniques; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tacrolimus | 2000 |
Inhibitory G protein alpha subunit (Gi alpha) expression and localization during human trophoblast differentiation.
Topics: Adenosine Diphosphate Ribose; Autoradiography; Cell Differentiation; Cell Membrane; Cell Nucleus; Culture Techniques; Fluorescent Antibody Technique, Indirect; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; NAD; Time Factors; Trophoblasts | 2000 |
Cell biology. New clue to age control in yeast.
Topics: Acetylation; Adenosine Diphosphate Ribose; Aging; Animals; DNA-Binding Proteins; Energy Intake; Gene Silencing; Histone Deacetylases; Histones; NAD; Poly(ADP-ribose) Polymerases; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Trans-Activators; Yeasts | 2000 |
Modification of adipocyte membrane adenylyl cyclase activity by NAD: evidence against NAD-induced endogenous ADP-ribosylation of Gsalpha protein.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adipocytes; Arginine; Cell Membrane; Cell Membrane Permeability; Cholera Toxin; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Membrane Proteins; NAD; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational | 2000 |
Endogenous ADP-ribosylation of the G protein beta subunit prevents the inhibition of type 1 adenylyl cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arginine; Catalysis; CHO Cells; Cricetinae; GTP-Binding Proteins; Hydrolysis; NAD; Signal Transduction; Substrate Specificity | 2000 |
Interaction of two classes of ADP-ribose transfer reactions in immune signaling.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Apoptosis; Arginine; Calcium; Cell Line; Cyclic ADP-Ribose; Cysteine; Flow Cytometry; Humans; Lymphocyte Activation; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NAD; NAD+ Nucleosidase; Phosphatidylinositol Diacylglycerol-Lyase; Poly(ADP-ribose) Polymerases; Signal Transduction; T-Lymphocytes; Transfection; Type C Phospholipases | 2000 |
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases.
Topics: Acetylation; Adenosine Diphosphate Ribose; Animals; Chickens; Fungal Proteins; Gene Silencing; Histone Deacetylases; Histones; Lysine; Multigene Family; NAD; Niacinamide; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Trans-Activators | 2000 |
Direct NAD(P)H hydrolysis into ADP-ribose(P) and nicotinamide induced by reactive oxygen species: a new mechanism of oxygen radical toxicity.
Topics: Adenosine Diphosphate Ribose; Animals; Free Radicals; Hydrolysis; In Vitro Techniques; Male; Models, Biological; Myocardial Reperfusion Injury; NAD; NADP; Niacinamide; Rats; Rats, Wistar; Reactive Oxygen Species | 2000 |
Mouse T-cell antigen rt6.1 has thiol-dependent NAD glycohydrolase activity.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antigens, Differentiation, T-Lymphocyte; COS Cells; Cysteine; Dithiothreitol; Escherichia coli; Ethylmaleimide; Histocompatibility Antigens; Hydrolysis; Kinetics; Macrophages, Peritoneal; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mutation; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases; Recombinant Fusion Proteins; Sulfhydryl Compounds; T-Lymphocytes; Transfection | 2000 |
Diphtheria toxin NAD affinity and ADP ribosyltransferase activity are reduced at tryptophan 153 substitutions for alanine or phenylalanine.
Topics: Adenosine Diphosphate Ribose; Alanine; Amino Acid Substitution; Diphtheria Toxin; Mutagenesis, Site-Directed; NAD; Peptide Fragments; Phenylalanine; Poly(ADP-ribose) Polymerases; Temperature; Tryptophan | 2000 |
Role of NAD(+) in the deacetylase activity of the SIR2-like proteins.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Chromatography, High Pressure Liquid; Histone Deacetylases; Histones; Kinetics; Molecular Sequence Data; NAD; Niacinamide; Peptide Fragments; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Substrate Specificity; Trans-Activators | 2000 |
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Histone Deacetylases; Histones; Molecular Sequence Data; Molecular Structure; NAD; O-Acetyl-ADP-Ribose; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Trans-Activators | 2000 |
Extracellular cyclic ADP-ribose potentiates ACh-induced contraction in bovine tracheal smooth muscle.
Topics: Acetylcholine; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Bronchoconstriction; Calcium; Cattle; Cyclic ADP-Ribose; Extracellular Space; In Vitro Techniques; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Smooth; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Paracrine Communication; Receptor Cross-Talk; Respiratory Mucosa; Trachea; Vasodilator Agents | 2001 |
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product.
Topics: Acetylation; Adenosine Diphosphate Ribose; Coenzymes; Fungal Proteins; Gene Expression Regulation, Fungal; Gene Silencing; Histone Deacetylases; Histones; Hydrolysis; Models, Biological; NAD; O-Acetyl-ADP-Ribose; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Trans-Activators | 2001 |
Chain length analysis of ADP-ribose polymers generated by poly(ADP-ribose) polymerase (PARP) as a function of beta-NAD+ and enzyme concentrations.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Hydrolysis; NAD; Poly(ADP-ribose) Polymerases; Polymers; Thymus Gland | 2000 |
How the sperm triggers development of the egg: what have we learned and what can we expect in the next millennium?
Topics: Adenosine Diphosphate Ribose; Animals; Calcium Signaling; Cyclic ADP-Ribose; Cyclic GMP; Embryology; Forecasting; Inositol 1,4,5-Trisphosphate; Microinjections; NAD; Nitric Oxide; Oocytes; Phosphatidylinositol Diacylglycerol-Lyase; Sea Urchins; Sperm-Ovum Interactions; Type C Phospholipases; Zygote | 2000 |
O-ADP-Ribosylation in the NAD/NADase system: 2-alkanols as efficient substrates.
Topics: Adenosine Diphosphate Ribose; Alcohols; Magnetic Resonance Spectroscopy; NAD; NAD+ Nucleosidase; Spectrometry, Mass, Fast Atom Bombardment; Substrate Specificity | 2001 |
Novel mechanisms involved in superoxide anion radical-triggered Ca2+ release from cardiac sarcoplasmic reticulum linked to cyclic ADP-ribose stimulation.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Calmodulin; Cyclic ADP-Ribose; Dogs; Electron Spin Resonance Spectroscopy; Hypoxanthine; Myocardium; NAD; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1999 |
Paracrine roles of NAD+ and cyclic ADP-ribose in increasing intracellular calcium and enhancing cell proliferation of 3T3 fibroblasts.
Topics: 3T3 Cells; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Binding Sites; Calcium; Cell Division; Cell Membrane; Coculture Techniques; Connexin 43; Cyclic ADP-Ribose; Cytosol; Kinetics; Membrane Glycoproteins; Mice; Models, Biological; Multienzyme Complexes; NAD; NAD+ Nucleosidase; Oligodeoxyribonucleotides, Antisense; Recombinant Proteins; Transfection | 2001 |
Mobilization of Ca2+ by cyclic ADP-ribose from the endoplasmic reticulum of cauliflower florets.
Topics: Adenosine Diphosphate Ribose; Brassica; Calcium; Cell Fractionation; Cyclic ADP-Ribose; Endoplasmic Reticulum, Rough; Intracellular Membranes; Kinetics; Microsomes; NAD; Plant Stems; Vacuoles | 2001 |
Regulation of glutamate dehydrogenase by reversible ADP-ribosylation in mitochondria.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Cations, Divalent; Cattle; Glutamate Dehydrogenase; Guanosine Diphosphate; Magnesium; Mitochondria, Liver; Molecular Sequence Data; NAD; NADP | 2001 |
The NADH diphosphatase encoded by the Saccharomyces cerevisiae NPY1 nudix hydrolase gene is located in peroxisomes.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Amino Acid Sequence; Binding Sites; Chromatography; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Green Fluorescent Proteins; Kinetics; Luminescent Proteins; Microscopy, Fluorescence; Molecular Sequence Data; NAD; NADP; Peroxisomes; Protein Binding; Pyrophosphatases; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Subcellular Fractions; Substrate Specificity; Time Factors | 2001 |
Significance of ecto-cyclase activity of CD38 in insulin secretion of mouse pancreatic islet cells.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Cyclic ADP-Ribose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NAD; NAD+ Nucleosidase; Second Messenger Systems | 2001 |
Rapid induction of naive T cell apoptosis by ecto-nicotinamide adenine dinucleotide: requirement for mono(ADP-ribosyl)transferase 2 and a downstream effector.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antigens, Differentiation, T-Lymphocyte; Apoptosis; Extracellular Space; Female; Glycosylphosphatidylinositols; Histocompatibility Antigens; Immunosuppressive Agents; Interphase; Isoenzymes; Lymphocyte Activation; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NZB; Mice, Knockout; NAD; Poly(ADP-ribose) Polymerases; Rabbits; Rats; T-Lymphocytes | 2001 |
Extracellular NAD(+) induces calcium signaling and apoptosis in human osteoblastic cells.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Apoptosis; Calcium; Calcium Signaling; Cell Count; Cell Division; Cell Line; Chelating Agents; Cyclic ADP-Ribose; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Fluorescent Dyes; Fura-2; Humans; Membrane Glycoproteins; Microscopy, Video; NAD; NAD+ Nucleosidase; Osteoblasts; Ryanodine; Stimulation, Chemical; Thapsigargin | 2001 |
Evidence of a role for cyclic ADP-ribose in calcium signalling and neurotransmitter release in cultured astrocytes.
Topics: Adenosine Diphosphate Ribose; Administration, Topical; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation; Astrocytes; Calcium Signaling; Cell Communication; Cells, Cultured; Coculture Techniques; Connexin 43; Cyclic ADP-Ribose; gamma-Aminobutyric Acid; Glutamic Acid; Glycyrrhetinic Acid; Hippocampus; Immunoblotting; Membrane Glycoproteins; Microscopy, Fluorescence; Models, Neurological; NAD; NAD+ Nucleosidase; Neurons; Neurotransmitter Agents; Rats; Spectrometry, Fluorescence | 2001 |
Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Monophosphate; ADP Ribose Transferases; Animals; Antigens, Differentiation, T-Lymphocyte; Cell Membrane; Cells, Cultured; Cholera Toxin; Female; Histocompatibility Antigens; Immunosuppressive Agents; Lymphocyte Activation; Male; Membrane Glycoproteins; Mitogens; NAD; NAD+ Nucleosidase; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphorus Radioisotopes; Poly(ADP-ribose) Polymerases; Pyrophosphatases; Rats; Rats, Inbred BB; Rats, Inbred WF; T-Lymphocytes; Type C Phospholipases; Virulence Factors, Bordetella | 2001 |
Biochemistry. TRP ion channels--two proteins in one.
Topics: Adenosine Diphosphate Ribose; Amino Acid Motifs; Animals; Calcium Channels; Catalysis; Catalytic Domain; Crystallography, X-Ray; Evolution, Molecular; Ion Channel Gating; Ion Channels; Membrane Proteins; Mutation; NAD; Patch-Clamp Techniques; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyrophosphatases; TRPM Cation Channels | 2001 |
Immunocyte Ca2+ influx system mediated by LTRPC2.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Apoptosis; Calcium; Calcium Channels; Cell Line; Eosinophils; Humans; Ion Channels; Jurkat Cells; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Monocytes; NAD; NAD+ Nucleosidase; Patch-Clamp Techniques; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; TRPM Cation Channels | 2001 |
Kinetic competence of the cADP-ribose-CD38 complex as an intermediate in the CD38/NAD+ glycohydrolase-catalysed reactions: implication for CD38 signalling.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Catalysis; Cattle; Cyclic ADP-Ribose; Kinetics; Macromolecular Substances; Models, Chemical; NAD; NAD+ Nucleosidase; Signal Transduction | 2001 |
Glyceraldehyde-3-phosphate dehydrogenase is negatively regulated by ADP-ribosylation in the fungus Phycomyces blakesleeanus.
Topics: Adenosine Diphosphate Ribose; Arginine; Glyceraldehyde-3-Phosphate Dehydrogenases; Models, Biological; Molecular Weight; NAD; Phycomyces; Protein Processing, Post-Translational; Spores, Fungal | 2001 |
The effect of carvedilol on enhanced ADP-ribosylation and red blood cell membrane damage caused by free radicals.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Adrenergic Antagonists; Animals; Blood Viscosity; Carbazoles; Carvedilol; Erythrocyte Membrane; Hemorheology; Humans; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; NAD; Perfusion; Poly(ADP-ribose) Polymerases; Propanolamines; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction | 2001 |
A quantitative analysis for the ADP-ribosylation activity of pertussis toxin: an enzymatic-HPLC coupled assay applicable to formulated whole cell and acellular pertussis vaccine products.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Biological Assay; Chromatography, High Pressure Liquid; Fluorescent Dyes; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Humans; In Vitro Techniques; Mass Spectrometry; Molecular Sequence Data; NAD; Peptides; Pertussis Toxin; Pertussis Vaccine; Vaccines, Acellular; Virulence Factors, Bordetella | 2001 |
Mono(ADP-ribosyl)ation of 2'-deoxyguanosine residue in DNA by an apoptosis-inducing protein, pierisin-1, from cabbage butterfly.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Apoptosis; Deoxyguanosine; DNA; HeLa Cells; Humans; Insect Proteins; NAD | 2001 |
A self-restricted CD38-connexin 43 cross-talk affects NAD+ and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblasts.
Topics: 3T3 Cells; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Base Sequence; Calcium; Connexin 43; Cyclic ADP-Ribose; DNA Primers; Enzyme Activation; Fibroblasts; Membrane Glycoproteins; Mice; NAD; NAD+ Nucleosidase; Phosphorylation; Protein Kinase C | 2001 |
Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice.
Topics: Adenosine Diphosphate Ribose; Animals; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Brain; Cell Cycle Proteins; Cerebellum; DNA Damage; DNA-Binding Proteins; In Situ Nick-End Labeling; Mice; Mitochondria; NAD; NADP; Oxygen Consumption; Protein Serine-Threonine Kinases; Tumor Suppressor Proteins | 2002 |
Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium Signaling; Chemotaxis, Leukocyte; Cyclic ADP-Ribose; Lymphoid Tissue; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; NAD; NAD+ Nucleosidase; Neutrophils; Pneumococcal Infections; Ryanodine; Streptococcus pneumoniae | 2001 |
Metabolism of NAD+ in nuclei of Saccharomyces cerevisiae during stimulation of its biosynthesis by nicotinamide.
Topics: Adenosine Diphosphate Ribose; Cell Nucleus; NAD; Niacinamide; Poly(ADP-ribose) Polymerases; Pyrophosphatases; Saccharomyces cerevisiae | 2001 |
Assay for ADP-ribosyl cyclase by reverse-phase high-performance liquid chromatography.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Aplysia; Chromatography, High Pressure Liquid; Humans; Jurkat Cells; Leukemia; Membrane Glycoproteins; NAD; NAD+ Nucleosidase; Subcellular Fractions; T-Lymphocytes | 2001 |
Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Arabinose; Archaeal Proteins; Bacterial Proteins; Deuterium Oxide; Enzyme Inhibitors; Fungal Proteins; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Isomerism; Kinetics; Molecular Sequence Data; NAD; Nuclear Magnetic Resonance, Biomolecular; O-Acetyl-ADP-Ribose; Oxygen Isotopes; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Sirtuin 2; Sirtuins; Substrate Specificity; Trans-Activators | 2001 |
A novel cycling assay for cellular cADP-ribose with nanomolar sensitivity.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium Signaling; Cyclic ADP-Ribose; NAD; Rats; Sensitivity and Specificity | 2002 |
Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases.
Topics: Acetylesterase; Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Catalysis; Cell Cycle; Chick Embryo; Drosophila Proteins; Histone Deacetylases; Molecular Sequence Data; NAD; O-Acetyl-ADP-Ribose; Phenotype; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Sirtuin 2; Sirtuins; Trans-Activators | 2002 |
Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Chromatography, High Pressure Liquid; Histone Deacetylases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; NAD; O-Acetyl-ADP-Ribose; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Trans-Activators | 2002 |
Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.
Topics: Adenosine Diphosphate Ribose; Adult; Base Sequence; Calcium; Calcium Channels; Cloning, Molecular; Humans; Hydrogen Peroxide; Ion Channels; Membrane Proteins; Molecular Sequence Data; NAD; Oxidative Stress; TRPM Cation Channels | 2002 |
NAD binding induces conformational changes in Rho ADP-ribosylating clostridium botulinum C3 exoenzyme.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Motifs; Binding Sites; Botulinum Toxins; NAD; Protein Conformation | 2002 |
Structural basis for the NAD-dependent deacetylase mechanism of Sir2.
Topics: Adenosine Diphosphate Ribose; Archaea; Binding Sites; Catalytic Domain; Crystallization; Histone Deacetylases; NAD; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Structure-Activity Relationship | 2002 |
Kinetics of the transhydrogenase reaction catalyzed by mitochondrial NADH:ubiquinone oxidoreductase (complex I).
Topics: Adenosine Diphosphate Ribose; Anthraquinones; Catalysis; Electron Transport Complex I; Kinetics; Mitochondria; NAD; NADH, NADPH Oxidoreductases | 2002 |
Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD.
Topics: Adenosine Diphosphate Ribose; Base Sequence; Calcium Channels; Cell Line; DNA Primers; Gene Expression Profiling; Humans; Ion Channels; Membrane Proteins; NAD; Neutrophils; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; TRPC Cation Channels; TRPM Cation Channels | 2003 |
A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14-3-3gamma.
Topics: 14-3-3 Proteins; Adenosine Diphosphate Ribose; Animals; Brain; Brain Injuries; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Enzyme Inhibitors; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proteins; Tyrosine 3-Monooxygenase | 2003 |
Identification of regulatory domains in ADP-ribosyltransferase-1 that determine transferase and NAD glycohydrolase activities.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Agmatine; Amino Acid Sequence; Animals; Base Sequence; Catalytic Domain; DNA Primers; In Vitro Techniques; Mice; Molecular Sequence Data; NAD; NAD+ Nucleosidase; Protein Structure, Tertiary; Rabbits; Recombinant Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Species Specificity | 2003 |
A FlashPlate assay for the identification of PARP-1 inhibitors.
Topics: Adenosine Diphosphate Ribose; Biochemistry; Cell Nucleus; Dose-Response Relationship, Drug; Drug Design; Drug Industry; Enzyme Inhibitors; HeLa Cells; Humans; Inhibitory Concentration 50; Kinetics; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Polymers | 2003 |
Enzymatic assays for NAD-dependent deacetylase activities.
Topics: Acetylation; Adenosine Diphosphate Ribose; Animals; Chickens; Electrophoresis, Polyacrylamide Gel; Histone Deacetylases; Histones; Indicators and Reagents; Kinetics; NAD; Peptides; Sirtuins; Substrate Specificity | 2003 |
Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry.
Topics: Acetylation; Adenosine Diphosphate Ribose; Animals; Archaeoglobus fulgidus; Base Pairing; Gene Expression Regulation, Fungal; Histone Deacetylases; Lysine; Mice; Models, Biological; NAD; Niacinamide; Oxygen; Peptide Fragments; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Sirtuin 2; Sirtuins; Species Specificity | 2003 |
NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD+ levels in Saccharomyces cerevisiae.
Topics: Adenosine Diphosphate Ribose; Fungal Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Glutathione Transferase; Histone Deacetylases; Histones; NAD; Niacinamide; Nuclear Proteins; Promoter Regions, Genetic; Recombinant Proteins; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirtuins | 2003 |
Fluorometric studies of ligand-induced conformational changes of CD38.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Binding Sites; Humans; Hydrolysis; Kinetics; Ligands; Membrane Glycoproteins; Mice; Models, Molecular; NAD; Niacinamide; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Temperature; Tryptophan | 2003 |
Toward the elucidation of the catalytic mechanism of the mono-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exotoxin A.
Topics: 1-Naphthylamine; Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Monophosphate; ADP Ribose Transferases; Bacterial Toxins; Binding, Competitive; Catalysis; Enzyme Activation; Exotoxins; Fluorescence Resonance Energy Transfer; Kinetics; Mutagenesis, Site-Directed; NAD; Naphthalimides; Niacinamide; Peptide Elongation Factor 2; Protein Binding; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Quinolones; Recombinant Proteins; Substrate Specificity; Virulence Factors | 2004 |
Structural basis for the mechanism and regulation of Sir2 enzymes.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Archaea; Archaeal Proteins; Catalytic Domain; Lysine; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; NAD; Protein Binding; Sequence Homology, Amino Acid; Sirtuins; Structure-Activity Relationship | 2004 |
Regulatory role of lactate in wound repair.
Topics: Adenosine Diphosphate Ribose; Animals; Collagen; Fibroblasts; Humans; Immunohistochemistry; Lactic Acid; Macrophages; NAD; Neovascularization, Physiologic; Vascular Endothelial Growth Factor A; Wound Healing | 2004 |
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Topics: Adenosine Diphosphate Ribose; Binding Sites; Histone Deacetylases; Models, Molecular; NAD; Niacinamide; Protein Conformation; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Thermodynamics | 2004 |
Extracellular NAD+ regulates intracellular free calcium concentration in human monocytes.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Calcium; Cells, Cultured; Cytosol; Humans; Membrane Glycoproteins; Monocytes; NAD; Signal Transduction | 2004 |
Active-site conformational changes associated with hydride transfer in proton-translocating transhydrogenase.
Topics: Adenosine Diphosphate Ribose; Binding Sites; Crystallization; Crystallography, X-Ray; Electron Transport; Humans; NAD; NADP; NADP Transhydrogenases; Nucleic Acid Conformation; Oxidation-Reduction; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Protons; Recombinant Proteins; Rhodospirillum rubrum | 2004 |
The mitochondrial ADPR link between Ca2+ store release and Ca2+ influx channel opening in immune cells.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Diffusion; Ion Channel Gating; Leukocytes; Mitochondria; Models, Biological; NAD | 2004 |
ADP-ribosylation of integrin alpha7 modulates the binding of integrin alpha7beta1 to laminin.
Topics: Adenosine Diphosphate Ribose; Animals; Antigens, CD; Cations, Divalent; Cell Differentiation; Cell Line; Cells, Cultured; Integrin alpha Chains; Integrins; Laminin; Magnesium; Manganese; Mice; NAD; Protein Binding; Protein Conformation | 2005 |
Effect of oxidative stress on in vivo ADP-ribosylation of eukaryotic elongation factor 2.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bacterial Proteins; Carbon Radioisotopes; Diphtheria Toxin; Humans; Hydrogen Peroxide; K562 Cells; NAD; Oxidative Stress; Peptide Elongation Factor 2; Protein Binding; Protein Processing, Post-Translational | 2005 |
Mechanistic aspects of the deoxyribonuclease activity of diphtheria toxin.
Topics: Adenosine; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Azides; Binding Sites; Catalysis; Cations, Divalent; Cell Line; Cycloheximide; Diphtheria Toxin; DNA; Endodeoxyribonucleases; Humans; NAD; Niacinamide; Oligoribonucleotides; Peptide Elongation Factor 2; Protein Biosynthesis; Substrate Specificity | 2005 |
P2X7 receptor-dependent and -independent T cell death is induced by nicotinamide adenine dinucleotide.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Apoptosis; Cell Death; Cell Proliferation; Cells, Cultured; Female; Growth Inhibitors; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; NAD; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Signal Transduction; Substrate Specificity; T-Lymphocytes; Time Factors | 2005 |
CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Immunomagnetic Separation; In Vitro Techniques; L-Selectin; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; NAD; Phosphatidylserines; T-Lymphocytes | 2005 |
Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.
Topics: Adenosine Diphosphate Ribose; Amino Acid Substitution; Catalysis; Cysteine; Glutamate Dehydrogenase; Humans; Isoenzymes; Ketoglutaric Acids; Kinetics; NAD; p-Chloromercuribenzoic Acid | 2005 |
NAD-, NMN-, and NADP-dependent modification of dinitrogenase reductases from Rhodospirillum rubrum and Azotobacter vinelandii.
Topics: Adenosine Diphosphate Ribose; Azotobacter vinelandii; Dinitrogenase Reductase; NAD; NADP; Nicotinamide Mononucleotide; Rhodospirillum rubrum; Ribonucleotides | 2005 |
Analysis of Arabidopsis growth factor gene 1 (GFG1) encoding a nudix hydrolase during oxidative signaling.
Topics: Adenosine Diphosphate Ribose; Apoptosis; Arabidopsis; Arabidopsis Proteins; Base Sequence; Escherichia coli; Escherichia coli Proteins; Genetic Complementation Test; Hydrogen Peroxide; Molecular Sequence Data; Mutation; NAD; Nudix Hydrolases; Oxidation-Reduction; Ozone; Pseudomonas syringae; Pyrophosphatases; Reactive Oxygen Species; Signal Transduction; Superoxides | 2006 |
Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.
Topics: Acetylation; Adenosine Diphosphate Ribose; Alanine; Binding Sites; Catalysis; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutation; NAD; Protein Conformation; Sirtuins; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Thermodynamics | 2006 |
The simultaneous measurement of nicotinamide adenine dinucleotide and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Chromatography, Liquid; Erythrocytes; HL-60 Cells; Humans; Mice; Mice, Inbred BALB C; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2006 |
A nonradioactive, cell-free method for measuring protein synthesis inhibition by Pseudomonas exotoxin.
Topics: Adenosine Diphosphate Ribose; Bacterial Proteins; beta-Galactosidase; Cell-Free System; Enzyme Activation; Genes, Reporter; NAD; Peptide Elongation Factor 2; Protein Biosynthesis; Protein Synthesis Inhibitors; Transcription, Genetic | 2006 |
Human alpha-defensins neutralize toxins of the mono-ADP-ribosyltransferase family.
Topics: Adenosine Diphosphate Ribose; alpha-Defensins; Animals; Cell Death; Corynebacterium diphtheriae; Diphtheria Toxin; Exotoxins; HeLa Cells; Humans; Kinetics; Mice; NAD; Peptide Elongation Factor 2; Protein Binding; Substrate Specificity; Thermodynamics | 2006 |
Extracellular NAD+ metabolism modulates osteoclastogenesis.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Animals; Calcium; Cyclic ADP-Ribose; Lymphocytes; Macrophage Colony-Stimulating Factor; Mice; Mice, Inbred C57BL; Models, Biological; NAD; Osteoclasts | 2006 |
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.
Topics: Adenosine Diphosphate Ribose; Amino Acids; Animals; Caloric Restriction; Cell Line, Tumor; Down-Regulation; Glucose; Glutamate Dehydrogenase; Glutamine; Humans; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Knockout; Mitochondria; NAD; Protein Processing, Post-Translational; RNA, Small Interfering; Sirtuin 1; Sirtuins; Transfection | 2006 |
NAD+-induced vasotoxicity in the pericyte-containing microvasculature of the rat retina: effect of diabetes.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Apoptosis; Benzoxazoles; Cell Membrane Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Fluorescent Dyes; Microscopy, Fluorescence; NAD; Pericytes; Purinergic P2 Receptor Antagonists; Quinolinium Compounds; Rats; Rats, Long-Evans; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Retinal Vessels | 2006 |
ADP-ribosylation activity in pertussis vaccines and its relationship to the in vivo histamine-sensitisation test.
Topics: Adenosine Diphosphate Ribose; Animals; Chromatography, High Pressure Liquid; GTP-Binding Protein alpha Subunits, Gi-Go; Histamine; Mice; NAD; Pertussis Toxin; Pertussis Vaccine; Vaccines, Acellular | 2007 |
Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Eukaryotic Cells; NAD; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Thiamine; Thiamine Pyrophosphate; Thiazoles | 2007 |
AtNUDT7, a negative regulator of basal immunity in Arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis.
Topics: Adenosine Diphosphate Ribose; Arabidopsis; Arabidopsis Proteins; Cell Death; Homeostasis; Mutation; NAD; Nudix Hydrolases; Plant Diseases; Pseudomonas syringae; Pyrophosphatases; Reactive Oxygen Species; Salicylic Acid; Signal Transduction | 2007 |
Redox-dependent change of nucleotide affinity to the active site of the mammalian complex I.
Topics: Adenosine Diphosphate Ribose; Algorithms; Animals; Antimycin A; Binding Sites; Cattle; Electron Transport; Electron Transport Complex I; Enzyme Inhibitors; Mitochondria, Heart; Models, Biological; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Nucleotides; Oxidation-Reduction; Protein Binding; Reducing Agents; Rotenone; Structure-Activity Relationship; Submitochondrial Particles; Succinic Acid; Uncoupling Agents | 2007 |
Transformation products of extracellular NAD(+) in the rat liver: kinetics of formation and metabolic action.
Topics: Adenosine Diphosphate Ribose; Animals; Glucose; Infusion Pumps; Inosine; Liver; Male; NAD; Niacinamide; Pyruvic Acid; Rats; Rats, Wistar; Time Factors; Uric Acid | 2008 |
Infrared multiphoton dissociation and electron-induced dissociation as alternative MS/MS strategies for metabolite identification.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Carbohydrates; Electrons; Fourier Analysis; Glucose-6-Phosphate; Glycolysis; Molecular Structure; NAD; NADP; Phosphorylation; Photons; Tandem Mass Spectrometry | 2007 |
Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Animals; Bone Marrow Cells; Calcium; Cell Line; Chemotaxis; Dendritic Cells; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD; Neutrophils; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Sensitivity and Specificity; Structure-Activity Relationship; Time Factors | 2007 |
Characterization of a Listeria monocytogenes protein interfering with Rab5a.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Clone Cells; Endosomes; Glyceraldehyde-3-Phosphate Dehydrogenases; Listeria monocytogenes; Mice; Molecular Sequence Data; NAD; Phagosomes; rab5 GTP-Binding Proteins | 2008 |
A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Signaling; CHO Cells; Cricetinae; Cricetulus; Electrophysiology; Hydrogen Peroxide; NAD; Oxidants; Oxidative Stress; Patch-Clamp Techniques; Transfection; TRPM Cation Channels | 2008 |
Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Francisella tularensis; Kinetics; Manganese; Models, Molecular; Molecular Sequence Data; NAD; Nicotinamide-Nucleotide Adenylyltransferase; Protein Structure, Tertiary; Pyrophosphatases; Synechocystis | 2008 |
The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cell Line; Humans; Ion Channel Gating; Lymphocytes; Mice; NAD; Oxidants; Oxidative Stress; Patch-Clamp Techniques; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Second Messenger Systems; TRPM Cation Channels | 2008 |
Overexpression of an ADP-ribose pyrophosphatase, AtNUDX2, confers enhanced tolerance to oxidative stress in Arabidopsis plants.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Arabidopsis; Arabidopsis Proteins; DNA, Bacterial; Gene Expression Regulation, Plant; Mutagenesis, Insertional; NAD; Oxidative Stress; Plants, Genetically Modified; Pyrophosphatases | 2009 |
Transformation and action of extracellular NAD+ in perfused rat and mouse livers.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Chromatography, High Pressure Liquid; Gluconeogenesis; Inosine; Liver; Male; Mice; NAD; Niacinamide; Oxygen Consumption; Perfusion; Rats; Rats, Sprague-Dawley; Rats, Wistar; Uric Acid | 2009 |
Delocalization of nucleolar poly(ADP-ribose) polymerase-1 to the nucleoplasm and its novel link to cellular sensitivity to DNA damage.
Topics: Adenosine Diphosphate Ribose; Apoptosis; Apoptosis Inducing Factor; Camptothecin; Cell Nucleus; DNA Damage; DNA Repair; DNA Topoisomerases, Type I; Enzyme Inhibitors; HeLa Cells; Humans; Methylnitronitrosoguanidine; NAD; Nuclear Proteins; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Topoisomerase I Inhibitors; Transcription, Genetic | 2009 |
Niacin status, NAD distribution and ADP-ribose metabolism.
Topics: Adenosine Diphosphate Ribose; Animals; Humans; NAD; Niacin; Rats | 2009 |
Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.
Topics: Acetylation; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Alkynes; Animals; Biocatalysis; Diphtheria Toxin; HeLa Cells; Histone Deacetylases; Histones; Humans; Hydrolysis; Kinetics; Mice; Models, Biological; NAD; Peptide Elongation Factor 2; Phosphorus Radioisotopes; Saccharomyces cerevisiae; Sirtuins; Substrate Specificity | 2009 |
NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Erythrocytes; Hemolysis; L-Selectin; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; NAD; Phosphatidylserines; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Spleen; Stress, Physiological; T-Lymphocytes; Temperature | 2009 |
Structure and function of an ADP-ribose-dependent transcriptional regulator of NAD metabolism.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Binding Sites; Crystallography, X-Ray; DNA, Fungal; Hydrogen Bonding; Models, Molecular; NAD; Protein Conformation; RNA, Fungal; Saccharomyces; Sirtuins; Templates, Genetic; Transcription, Genetic | 2009 |
Leukocyte elastase inhibitor: a new regulator of PARP-1.
Topics: Adenosine Diphosphate Ribose; Animals; Blotting, Western; Cell Line; Cell Nucleus; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Endodeoxyribonucleases; Fluorescent Antibody Technique; Hydrogen Peroxide; Immunohistochemistry; Leukocyte Elastase; NAD; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Swine | 2009 |
Niacin status impacts chromatin structure.
Topics: Adenosine Diphosphate Ribose; Chromatin; Diet; Epigenesis, Genetic; Gene Expression Regulation; Histones; Humans; NAD; Niacin; Niacinamide; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Sirtuins | 2009 |
Pyridine nucleotide cycling and control of intracellular redox state in relation to poly (ADP-ribose) polymerase activity and nuclear localization of glutathione during exponential growth of Arabidopsis cells in culture.
Topics: Adenosine Diphosphate Ribose; Animals; Arabidopsis; Cell Cycle; Cells; Cyclization; Cytoplasm; Glutathione Disulfide; NAD; NADP; Oxidation-Reduction; Poly(ADP-ribose) Polymerases | 2009 |
AtNUDX6, an ADP-ribose/NADH pyrophosphohydrolase in Arabidopsis, positively regulates NPR1-dependent salicylic acid signaling.
Topics: Adaptation, Physiological; Adenosine Diphosphate Ribose; Antioxidants; Arabidopsis; Arabidopsis Proteins; Gene Knockout Techniques; NAD; Nudix Hydrolases; Pyrophosphatases; Salicylic Acid; Signal Transduction | 2010 |
Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells.
Topics: Adenosine Diphosphate Ribose; Adult; Blood Cells; Cell Death; Cell Survival; Cells; DNA Damage; DNA Repair; Female; Humans; Male; Methylnitronitrosoguanidine; Middle Aged; NAD; Neutrophils; Niacin; Nicotinic Acids; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational | 2010 |
Quantitative magnetic resonance imaging of enzyme activity on the cell surface: in vitro and in vivo monitoring of ADP-ribosyltransferase 2 on T cells.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antibodies, Monoclonal; Cell Line, Tumor; Cell Membrane; Ferric Compounds; Flow Cytometry; Linear Models; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Microscopy, Fluorescence; NAD; Reproducibility of Results; T-Lymphocytes; Whole Body Imaging | 2010 |
Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Humans; Hydrogen Peroxide; NAD; NADP; Oxidants; Oxidative Stress; TRPM Cation Channels; Xenopus laevis | 2010 |
Modulation of redox homeostasis under suboptimal conditions by Arabidopsis nudix hydrolase 7.
Topics: Adenosine Diphosphate Ribose; Arabidopsis; Arabidopsis Proteins; DNA, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Plant; Homeostasis; Mutation; NAD; Nudix Hydrolases; Oxidation-Reduction; Plants, Genetically Modified; Pyrophosphatases; Reactive Oxygen Species; RNA, Plant; Signal Transduction | 2010 |
Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches.
Topics: Acetylation; Adenosine Diphosphate Ribose; Archaeoglobus fulgidus; Biocatalysis; Computer Simulation; Kinetics; Lysine; NAD; Sirtuin 2 | 2010 |
Dynamic conformations of the CD38-mediated NAD cyclization captured in a single crystal.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Amino Acid Substitution; Catalytic Domain; Crystallography, X-Ray; Humans; In Vitro Techniques; Membrane Glycoproteins; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; NAD; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity | 2011 |
Structure and biochemical functions of SIRT6.
Topics: Adenosine Diphosphate Ribose; Amino Acid Motifs; Calorimetry; Catalytic Domain; Crystallography, X-Ray; Gene Expression Regulation; Histone Deacetylases; Humans; Kinetics; NAD; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sirtuins; Thermodynamics | 2011 |
Endogenous protein mono-ADP-ribosylation in Arabidopsis thaliana.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; ADP-Ribosylation Factors; Arabidopsis; Cysteine; Gene Expression Regulation, Plant; Genes, Plant; Glycosylation; NAD; Organ Specificity; Oxidative Stress; Plant Leaves; Protein Processing, Post-Translational | 2011 |
Mitochondria-localized NAD biosynthesis by nicotinamide mononucleotide adenylyltransferase in Jerusalem artichoke (Helianthus tuberosus L.) heterotrophic tissues.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Adenosine Triphosphate; Cell Fractionation; Chromatography, High Pressure Liquid; Diphosphates; Helianthus; Heterotrophic Processes; Hydrogen-Ion Concentration; Kinetics; Mitochondria; NAD; NADP; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Oxygen; Plant Tubers; Substrate Specificity; Temperature | 2011 |
A ternary mechanism for NADH oxidation by positively charged electron acceptors, catalyzed at the flavin site in respiratory complex I.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Cattle; Electron Transport Complex I; Electrons; Flavins; Herbicides; Mitochondria, Heart; NAD; Oxidation-Reduction; Paraquat; Ruthenium Compounds | 2011 |
Phytophthora sojae avirulence effector Avr3b is a secreted NADH and ADP-ribose pyrophosphorylase that modulates plant immunity.
Topics: Adenosine Diphosphate Ribose; Alleles; Genotype; Glycine max; Molecular Sequence Data; Mutation; NAD; Nicotiana; Nudix Hydrolases; Phosphorylases; Phytophthora; Plant Diseases; Plant Immunity; Pyrophosphatases; Reactive Oxygen Species; Virulence Factors | 2011 |
Structural studies of intermediates along the cyclization pathway of Aplysia ADP-ribosyl cyclase.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; Animals; Aplysia; Catalytic Domain; Crystallography, X-Ray; Models, Molecular; NAD | 2012 |
The ΔC splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Cell Proliferation; Gene Silencing; HEK293 Cells; HeLa Cells; Humans; Membrane Glycoproteins; NAD; Protein Isoforms; Reactive Oxygen Species; RNA, Small Interfering; TRPM Cation Channels | 2012 |
The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death.
Topics: Adenosine Diphosphate Ribose; Amino Acid Motifs; Animals; Apoptosis; Calcium-Binding Proteins; Gene Expression Regulation; HEK293 Cells; Hippocampus; Humans; Hydrogen Peroxide; Mice; Mutation; Myoclonic Epilepsy, Juvenile; NAD; Neurons; Oxidants; Protein Structure, Tertiary; TRPM Cation Channels | 2012 |
Adenosine 5-diphosphate-ribose is a neural regulator in primate and murine large intestine along with β-NAD(+).
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Colon; Gastrointestinal Motility; Macaca fascicularis; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscle, Smooth; Myocytes, Smooth Muscle; NAD; Neurotransmitter Agents; Purinergic P2Y Receptor Antagonists; Purines; Receptors, Purinergic P2Y1; Synaptic Transmission | 2012 |
Identification of novel components of NAD-utilizing metabolic pathways and prediction of their biochemical functions.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Bacteria; Escherichia coli Proteins; Evolution, Molecular; Genomics; Humans; Metabolic Networks and Pathways; Models, Biological; Molecular Sequence Annotation; Molecular Sequence Data; NAD; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Sequence Alignment; Sequence Homology, Amino Acid; Tankyrases | 2012 |
NAD(+) biosynthesis and salvage--a phylogenetic perspective.
Topics: Adenosine Diphosphate Ribose; Animals; Eukaryota; Humans; Metabolic Networks and Pathways; NAD; Niacinamide; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Protein Processing, Post-Translational; Saccharomyces cerevisiae | 2012 |
Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Alternative Splicing; Animals; HEK293 Cells; Humans; Ion Channel Gating; Mice; Mice, Inbred BALB C; NAD; Protein Isoforms; Protein Processing, Post-Translational; Protein Structure, Tertiary; Receptors, Purinergic P2X7; T-Lymphocytes, Regulatory | 2012 |
The ammonium/nitrate ratio is an input signal in the temperature-modulated, SNC1-mediated and EDS1-dependent autoimmunity of nudt6-2 nudt7.
Topics: Adenosine Diphosphate Ribose; Ammonium Compounds; Arabidopsis; Arabidopsis Proteins; DNA-Binding Proteins; Gene Expression Regulation, Plant; NAD; Nitrates; Nitric Oxide; Nudix Hydrolases; Pyrophosphatases; Signal Transduction; Temperature | 2013 |
CD8-β ADP-ribosylation affects CD8(+) T-cell function.
Topics: Adenosine Diphosphate Ribose; Animals; CD8 Antigens; CD8-Positive T-Lymphocytes; Cell Separation; Flow Cytometry; Lymphocyte Activation; Mice; Mice, Inbred C57BL; NAD | 2013 |
Investigation of NADH binding, hydride transfer, and NAD(+) dissociation during NADH oxidation by mitochondrial complex I using modified nicotinamide nucleotides.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Binding, Competitive; Cattle; Coenzymes; Electron Transport Complex I; Flavins; Hydrogen; Kinetics; Mitochondria, Heart; Models, Molecular; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction; Protein Binding | 2013 |
Molecular mechanism and functional role of brefeldin A-mediated ADP-ribosylation of CtBP1/BARS.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Alcohol Oxidoreductases; Animals; Binding Sites; Binding, Competitive; Blotting, Western; Brefeldin A; Cytosol; DNA-Binding Proteins; HeLa Cells; Humans; Membrane Glycoproteins; Models, Molecular; NAD; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Rats | 2013 |
Genomics-guided analysis of NAD recycling yields functional elucidation of COG1058 as a new family of pyrophosphatases.
Topics: Adenosine Diphosphate Ribose; Amidohydrolases; Base Sequence; Cloning, Molecular; Computational Biology; Genomics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Phylogeny; Protein Structure, Tertiary; Pyrophosphatases; Sequence Alignment; Sequence Analysis, DNA; Species Specificity | 2013 |
Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism.
Topics: Adenosine Diphosphate Ribose; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Heterocyclic Compounds, 4 or More Rings; Humans; NAD; Protein Conformation; Sirtuin 3 | 2013 |
Toxicological properties of the thiolated inorganic arsenic and arsenosugar metabolite thio-dimethylarsinic acid in human bladder cells.
Topics: Adenosine Diphosphate Ribose; Apoptosis; Arsenates; Arsenic; Arsenicals; Biological Availability; Cacodylic Acid; Caspase 2; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line; DNA Breaks, Double-Stranded; DNA Damage; Gene Expression Regulation; Glycoside Hydrolases; Humans; Hydrogen Peroxide; Monosaccharides; NAD; Nuclear Proteins; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Sulfhydryl Compounds; Urinary Bladder | 2014 |
Nudix hydrolase controls nucleotides and glycolytic mechanisms in hypoxic Aspergillus nidulans.
Topics: Adenosine Diphosphate Ribose; Aspergillus nidulans; Ethanol; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Lactic Acid; NAD; Nudix Hydrolases; Oxidation-Reduction; Oxygen; Pyrophosphatases; Up-Regulation | 2013 |
Mapping NAD(+) metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Aging; Animals; Brain; DNA Damage; Electron Transport; Female; Gene Knockdown Techniques; Lipid Peroxidation; Membrane Glycoproteins; Mitochondria; NAD; Oxidative Stress; Poly(ADP-ribose) Polymerases; Protein Carbonylation; Rats; Rats, Wistar; RNA, Small Interfering; Sirtuin 1; Tissue Distribution | 2014 |
NAD-dependent ADP-ribosylation of the human antimicrobial and immune-modulatory peptide LL-37 by ADP-ribosyltransferase-1.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antimicrobial Cationic Peptides; Arginine; Cathelicidins; Cell Line; Cell Membrane; GPI-Linked Proteins; Humans; Immunomodulation; Mass Spectrometry; NAD | 2015 |
Proteomics approaches to identify mono-(ADP-ribosyl)ated and poly(ADP-ribosyl)ated proteins.
Topics: Adenosine Diphosphate Ribose; Animals; Humans; Mass Spectrometry; NAD; Poly Adenosine Diphosphate Ribose; Proteins; Proteomics | 2015 |
Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.
Topics: Adenosine Diphosphate Ribose; Alicyclobacillus; Amino Acid Sequence; Azotobacter vinelandii; Bacterial Proteins; Binding Sites; Catalytic Domain; Coenzymes; Crystallography, X-Ray; Desulfurococcaceae; Ketol-Acid Reductoisomerase; Magnesium; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutant Proteins; NAD; NADP; Phosphorylation; Protein Folding; Recombinant Proteins; Sequence Alignment | 2015 |
Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate.
Topics: Adenosine Diphosphate Ribose; Animals; Humans; Ion Channel Gating; NAD; NADP; Protein Binding; Pyrophosphatases; TRPM Cation Channels; Xenopus | 2015 |
Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Bacterial Proteins; cdc42 GTP-Binding Protein; Crystallography, X-Ray; Escherichia coli; Gene Expression; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Ligands; Molecular Docking Simulation; Molecular Sequence Data; NAD; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Recombinant Proteins; Sequence Alignment | 2015 |
PARPs and ADP-Ribosylation: 50 Years … and Counting.
Topics: Adenosine Diphosphate Ribose; Biomedical Research; Biosynthetic Pathways; Forecasting; Humans; Interviews as Topic; Molecular Structure; NAD; Niacinamide; Nicotinamide Mononucleotide; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Time Factors | 2015 |
SnapShot: ADP-Ribosylation Signaling.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Biosynthetic Pathways; Humans; Models, Chemical; Molecular Structure; NAD; Niacinamide; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Signal Transduction | 2015 |
Nucleotide-Induced Membrane-Proximal Proteolysis Controls the Substrate Specificity of T Cell Ecto-ADP-Ribosyltransferase ARTC2.2.
Topics: ADAM Proteins; ADAM17 Protein; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Cell Line, Tumor; Cell Membrane; Flow Cytometry; Glycosylphosphatidylinositols; HEK293 Cells; Humans; L-Selectin; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NAD; Proteolysis; Receptors, Purinergic P2X7; Substrate Specificity; T-Lymphocyte Subsets; T-Lymphocytes | 2015 |
Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Catalytic Domain; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Molecular Sequence Data; NAD; Protein Structure, Secondary; Sirtuin 2; Sirtuin 3 | 2015 |
Ubiquitination independent of E1 and E2 enzymes by bacterial effectors.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; ADP Ribose Transferases; Amino Acid Motifs; Amino Acid Sequence; Bacterial Load; Bacterial Proteins; Biocatalysis; Endoplasmic Reticulum; Legionella pneumophila; Membrane Proteins; Molecular Sequence Data; NAD; rab GTP-Binding Proteins; Ubiquitin; Ubiquitin-Activating Enzymes; Ubiquitin-Conjugating Enzymes; Ubiquitination; Virulence Factors | 2016 |
Who Put the "A" in ATP? Generation of ATP from ADP-Ribose in the Nucleus for Hormone-Dependent Gene Regulation.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Cell Nucleus; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases | 2016 |
Key role of an ADP - ribose - dependent transcriptional regulator of NAD metabolism for fitness and virulence of Pseudomonas aeruginosa.
Topics: Adenosine Diphosphate Ribose; Animals; Bacterial Proteins; Cricetulus; Disease Models, Animal; Female; Gene Expression Regulation, Bacterial; Mice, Inbred C3H; NAD; Operon; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Transcription Factors; Virulence | 2017 |
Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.
Topics: 2,2'-Dipyridyl; Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Animals; Catalytic Domain; Crystallography, X-Ray; Formamides; Horses; Kinetics; Liver; Models, Molecular; NAD; Phenanthrolines; Protein Binding; Protein Conformation; Water; Zinc | 2017 |
Reversible mono-ADP-ribosylation of DNA breaks.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation; Animals; Cell Cycle Proteins; DNA; DNA Breaks; DNA Repair; Humans; Hydrolases; Models, Genetic; NAD; Poly(ADP-ribose) Polymerases | 2017 |
Characterization of a non-nudix pyrophosphatase points to interplay between flavin and NAD(H) homeostasis in Saccharomyces cerevisiae.
Topics: Adenosine Diphosphate Ribose; Cations; Cytosol; Dinitrocresols; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Mitochondria; NAD; Potassium; Pyrophosphatases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2018 |
Assessment of Intracellular Auto-Modification Levels of ARTD10 Using Mono-ADP-Ribose-Specific Macrodomains 2 and 3 of Murine Artd8.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Cytoplasm; Humans; Immunoprecipitation; Mice; NAD; Poly(ADP-ribose) Polymerases; Protein Domains; Protein Processing, Post-Translational; Proto-Oncogene Proteins | 2018 |
Hydrolysis of ADP-Ribosylation by Macrodomains.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; ADP-Ribosylation; Hydrolysis; Models, Molecular; Molecular Biology; NAD; Protein Domains; Protein Processing, Post-Translational; Proteins | 2018 |
Monitoring the Sensitivity of T Cell Populations Towards NAD
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Arginine; Mice; Molecular Biology; NAD; Receptors, Purinergic P2X7; T-Lymphocytes | 2018 |
Conformational changes on substrate binding revealed by structures of Methylobacterium extorquens malate dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Apoenzymes; Bacterial Proteins; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Genetic Vectors; Hydrogen Bonding; Kinetics; Malate Dehydrogenase; Malates; Methylobacterium extorquens; Models, Molecular; NAD; Oxaloacetic Acid; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Multimerization; Protons; Recombinant Proteins; Substrate Specificity | 2018 |
Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Bacterial Proteins; Clostridium thermocellum; Ligands; NAD; Phosphates; Protein Conformation; RNA, Transfer | 2019 |
Methods to study phosphoribosylated ubiquitin ligation and removal.
Topics: Adenosine Diphosphate Ribose; Bacterial Proteins; HEK293 Cells; Host-Pathogen Interactions; Humans; Legionella pneumophila; Legionnaires' Disease; NAD; Phosphoric Diester Hydrolases; rab GTP-Binding Proteins; Ubiquitin; Ubiquitination | 2019 |
Functional analysis of Arabidopsis and maize transgenic lines overexpressing the ADP-ribose/NADH pyrophosphohydrolase, AtNUDX7.
Topics: Adenosine Diphosphate Ribose; Arabidopsis; Arabidopsis Proteins; Droughts; Gene Expression Regulation, Plant; NAD; Oxidative Stress; Plants, Genetically Modified; Promoter Regions, Genetic; Pyrophosphatases; Seeds; Stress, Physiological; Zea mays | 2019 |
Reversible ADP-ribosylation of RNA.
Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; ADP Ribose Transferases; ADP-Ribosylation; Animals; Catalysis; Chromatin; DNA Repair; DNA Repair Enzymes; DNA, Single-Stranded; Escherichia coli; Humans; Hydrolases; Mice; NAD; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; RNA; Signal Transduction | 2019 |
Quartz Crystal Microbalance Detection of Poly(ADP-ribose) Polymerase-1 Based on Gold Nanorods Signal Amplification.
Topics: Adenosine Diphosphate Ribose; Biomarkers, Tumor; Cell Line, Tumor; Cetrimonium; Female; Gold; Humans; Limit of Detection; NAD; Nanotubes; Neoplasm Proteins; Niacinamide; Ovarian Neoplasms; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Quartz Crystal Microbalance Techniques; Static Electricity | 2019 |
Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; ADP-Ribosylation; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; NAD; Poly ADP Ribosylation; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Substrate Specificity | 2020 |
Targeting NAD
Topics: Acrylamides; Adenosine; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytokines; Drug Synergism; Humans; Membrane Glycoproteins; Multiple Myeloma; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Tumor Escape; Warburg Effect, Oncologic | 2020 |
Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Animals; Autophagosomes; Calcium; Carbon Monoxide; Cell Line; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Macrophages; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD; NADP; Ras Homolog Enriched in Brain Protein; RNA, Small Interfering; Sepsis; Sirtuin 1; TOR Serine-Threonine Kinases; Tristetraprolin | 2020 |
Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity.
Topics: A549 Cells; Adenosine Diphosphate Ribose; ADP-Ribosylation; Adult; Animals; Cell Line, Tumor; COVID-19; Female; Ferrets; Humans; Immunity, Innate; Male; Metabolome; Mice; Mice, Inbred C57BL; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyridinium Compounds; SARS-CoV-2 | 2020 |
Biomimetic α-selective ribosylation enables two-step modular synthesis of biologically important ADP-ribosylated peptides.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation; Biomimetic Materials; Catalysis; Click Chemistry; Histones; Ionic Liquids; NAD; Peptides; Protein Binding | 2020 |
NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Sequence; DNA; DNA Breaks, Double-Stranded; DNA Ligase ATP; DNA Repair; Humans; NAD | 2020 |
Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Bacterial Proteins; Bacterial Toxins; Catalytic Domain; Crystallography, X-Ray; DNA; DNA-Binding Proteins; Guanine; Kinetics; Molecular Dynamics Simulation; NAD; Protein Binding; Protein Conformation; RNA; Streptomyces; Structure-Activity Relationship | 2021 |
Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites.
Topics: Adenosine Diphosphate Ribose; Binding Sites; Biophysical Phenomena; Crystallization; Crystallography, X-Ray; Humans; Ligands; Middle East Respiratory Syndrome Coronavirus; Models, Molecular; NAD; Nuclear Magnetic Resonance, Biomolecular; Poly Adenosine Diphosphate Ribose; Protein Binding; Protein Domains; Protein Stability; Thermodynamics; Viral Proteins | 2021 |
Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate Ribose; ADP-Ribosylation; GPI-Linked Proteins; Humans; Membrane Proteins; NAD | 2022 |
Profiling of the ADP-Ribosylome in Living Cells.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation; Humans; NAD; Protein Processing, Post-Translational; Proteome | 2022 |
Crystal structures of pertussis toxin with NAD
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation; Bordetella pertussis; Cytosol; NAD; Pertussis Toxin; Virulence Factors, Bordetella | 2022 |
NAD-catabolizing ectoenzymes of Schistosoma mansoni.
Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; NAD; Niacinamide; Schistosoma mansoni | 2022 |
Structural Insights into
Topics: Adenosine Diphosphate Ribose; Histidine; Molecular Dynamics Simulation; NAD; Peptide Elongation Factor 2; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A | 2023 |
Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; ADP-Ribosylation; Animals; HeLa Cells; Humans; Mice; NAD; Nucleic Acids; Phosphotransferases (Alcohol Group Acceptor); Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2023 |
Structural basis for Tpt1-catalyzed 2'-PO
Topics: Adenosine Diphosphate Ribose; NAD; NADP; Phosphates; RNA; RNA, Transfer | 2023 |
Identification of NAD-RNA species and ADPR-RNA decapping in Archaea.
Topics: Adenosine Diphosphate Ribose; Archaea; Chromatography, Liquid; NAD; RNA; Tandem Mass Spectrometry | 2023 |