nad has been researched along with 3-aminobenzamide in 106 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 42 (39.62) | 18.7374 |
1990's | 40 (37.74) | 18.2507 |
2000's | 21 (19.81) | 29.6817 |
2010's | 3 (2.83) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Ezell, EL; Jackson, GR; Perez-Polo, JR; Post, JF; Werrbach-Perez, K | 1 |
Lindahl, T; Satoh, MS | 1 |
Farber, JL; Yamamoto, K | 1 |
Choi, HS; Han, DM; Kim, WJ; Park, JK; Park, SD; Park, YS; Yu, JE | 1 |
Durkacz, BW; Harris, AL; Moses, K; Willmore, E | 1 |
Drevenstedt, B; Hoshino, J; Kröger, H; Schalge, S | 1 |
Kirkland, JB | 1 |
Brunborg, G; Dybing, E; Holme, JA; Låg, M; Søderlund, J | 1 |
Catsoulacos, P; Dozi-Vassiliades, J; Mioglou, E; Mourelatos, D; Petrou, C | 1 |
Konno, S; Oronsky, AL; Wu, JM; Zhao, B | 1 |
Ben-Hur, E; Elkind, MM; Shibuya, ML; Wells, RL | 1 |
Singh, N | 1 |
Cesarone, CF; Gallo, G; Giannoni, P; Orunesu, M; Scarabelli, L | 1 |
Alaoui Jamali, MA; Boudreau, A; Castonguay, A; Lautier, D; Poirier, D; Poirier, G | 1 |
Cohen, GM; Stubberfield, CR | 2 |
Cantoni, O; Cattabeni, F; Cerutti, P; Meyn, RE; Murray, D; Stocchi, V | 1 |
Andreoli, SP | 1 |
Ganeshaguru, K; Hoffbrand, AV; Latini, L; Piga, A | 1 |
Benjamin, RC; Jacobson, EL; Jacobson, MK; Moss, J; Rankin, PW | 1 |
Jones, DP; McConkey, DJ; Nicotera, P; Orrenius, S | 1 |
Ebel, JP; Gilson, G; Remy, P | 1 |
Lane, DA; Nadeau, D | 1 |
Cochrane, CG; Hinshaw, DB; Hyslop, PA; Schraufstatter, IU; Sklar, LA; Spragg, RG | 1 |
Chen, XR; Dai, YF; Yu, YN | 2 |
Wiencke, JK | 1 |
Barankiewicz, J; Cohen, A | 1 |
Berger, NA; Berger, SJ; Krothapalli, D; Manory, I; Sudar, DC | 1 |
Hayward, AR; Herberger, M | 1 |
Agarwal, S; Drysdale, BE; Shin, HS | 1 |
Armato, U; Menapace, L; Romano, F | 1 |
Schwartz, JL; Weichselbaum, RR | 1 |
Cerutti, P; Poirier, G; Singh, N | 1 |
Arlett, CF; James, MR; Lehmann, AR; Poirier, V | 1 |
Ben-Hur, E; Elkind, MM; Lindquist, K | 1 |
Gowans, BJ; Henderson, JF; Hunting, DJ | 1 |
Gaal, JC; Pearson, CK | 1 |
Adolph, KW | 1 |
Dritschilo, A; Kasid, UN; Lubet, RA; Smulson, ME; Stefanik, DF | 1 |
Berger, NA; Das, SK | 1 |
Cantoni, O; Cattabeni, F; Sestili, P; Stocchi, V | 1 |
Durkacz, BW; Harris, AL; Moses, K | 1 |
Emi, Y; Fujiwara, K; Konishi, Y; Nakae, D; Ohnishi, T; Shiraiwa, K; Takahashi, S; Tsutsumi, M; Uchida, K; Ueda, K | 1 |
Gowans, BJ; Hunting, DJ | 1 |
Althaus, FR; Alvarez-Gonzalez, R; Eichenberger, R | 1 |
Silver, AR; Stratford, IJ; Walling, JM | 1 |
Brinkley, FB; Gross, CL; Johnson, JB; Meier, HL; Papirmeister, B | 1 |
Berger, NA; Surowy, CS | 1 |
Schwartz, JL | 1 |
Adolph, KW; Song, MK | 1 |
Collins, A | 1 |
Ben-Hur, E; Elkind, MM; Utsumi, H | 1 |
Pearson, CK; Walker, J | 1 |
Allen, CM; Durkacz, BW; Paine, AJ; Shall, S | 1 |
Matsudaira, H; Tanaka, O; Ueno, AM | 1 |
Fujiwara, Y; Goto, K; Ichihashi, M; Yamamoto, K | 1 |
Coppola, S; Ghibelli, L; Maresca, V; Nosseri, C | 1 |
Hoyt, DG; Lazo, JS | 1 |
Holm, BA; Hudak, BB; Maloney, C; Sokolowski, J; Tufariello, J | 1 |
Burkart, V; Bürkle, A; Fehsel, K; Heller, B; Kolb, H; Radons, J; Wagner, EF; Wang, ZQ | 1 |
Boorstein, RJ; Haldar, J; Poirier, G; Putnam, D | 1 |
Berger, NA; Berger, RB; Berger, SJ; Chatterjee, S; Cheng, MF | 1 |
Burkart, V; Bürkle, A; Hartmann, B; Heller, B; Kolb, H; Kröncke, KD; Radons, J; Rodriguez, ML | 1 |
Coppola, S; Ghibelli, L; Nosseri, C | 1 |
Durkacz, BW; Willmore, E | 1 |
Farber, JL; Tsukidate, K; Yamamoto, K | 1 |
Beckmann, G; Hoshino, J; Kröger, H | 1 |
Kominami, R; Mishima, Y; Muramatsu, M; Nishimura, T | 1 |
Bernardi, R; Donzelli, M; Guano, F; Negri, C; Prosperi, E; Scovassi, AI; Torti, M | 1 |
Ochi, K; Penyige, A; Shima, J | 1 |
Blundell, G; Jones, BG; Rose, FA; Tudball, N | 1 |
Applegren, N; Bers, G; Hickey, R; Hilz, H; Malkas, L; Rosenthal, DS; Simbulan-Rosenthal, CM; Smulson, ME; Wu, Y | 1 |
Alvarez, L; Farber, JL; García, C; Mato, JM; Pajares, MA; Pastorino, JG; Sánchez-Góngora, E; Viña, JR | 1 |
Endres, M; Moskowitz, MA; Namura, S; Waeber, C; Wang, ZQ | 1 |
Caputi, AP; Cuzzocrea, S; Zingarelli, B | 1 |
de Lange, T; Giriat, I; Schmitt, A; Smith, S | 1 |
Amor, Y; Babiychuk, E; Inzé, D; Levine, A | 1 |
Karczewski, JM; Noordhoek, J; Peters, JG | 1 |
Al-Saffar, NM; Clarke, PA; Cunningham, DC; DiStefano, F; Griffiths, JR; Leach, MO; McCoy, CL; Robertson, D; Ronen, SM; Smith, TA; Titley, J | 1 |
Grant, RS; Kapoor, V; Matanovic, G; Passey, R; Smythe, G | 1 |
Hirata, K; Mitaka, T; Mizuguchi, T; Mochizuki, Y; Sato, F | 1 |
Chen, D; Chen, J; Henshall, DC; Nagayama, T; Pei, W; Simon, RP; Stetler, RA | 1 |
Cheung, A; Zhang, J | 1 |
Espinosa, M; Grant, RS; Kapoor, V; Naif, H | 1 |
Komatsu, N; Muramatsu, T; Nakagawa, M; Oda, T | 1 |
Chan, SL; Culmsee, C; Guo, Z; Kruman, II; Kruman, Y; Mattson, MP; Penix, L | 1 |
Al-Affar, EB; Liaudet, L; Szabó, C; Yang, Z | 1 |
Cantoni, O; Guidarelli, A; Palomba, L; Scovassi, AI | 1 |
Marecki, JC; McCord, JM | 1 |
Cole, KK; Perez-Polo, JR | 1 |
Imamura, H; Kido, M; Kobayashi, Y; Ninomiya, H; Nogi, S; Okada, T; Otani, H; Uchiyama, T | 1 |
Cecchi, C; Celli, A; Fiorillo, C; Formigli, L; Giannini, L; Liguori, P; Nassi, N; Nassi, P; Nediani, C; Perna, AM; Ponziani, V; Tani, A | 1 |
Asakura, S; Caldecott, KW; de Murcia, G; Hester, SD; Nakamura, J; Swenberg, JA | 1 |
Hasmann, M; Nüssler, V; Pelka-Fleischer, R; Pogrebniak, A; Schemainda, I | 1 |
Komeda, M; Miwa, S; Nishimura, K; Tanaka, S; Toyokuni, S; Ueda, K; Unimonh, O; Yamazaki, K | 1 |
Araki, T; Milbrandt, J; Sasaki, Y | 1 |
Linning, KD; Olson, LK; Szabo, C; Tai, MH; Ye, DZ | 1 |
Hatano, T; Maruta, H; Okita, N; Takasawa, R; Tanuma, S; Uchiumi, F | 1 |
Misra, HS; Raju, KK; Sharma, A | 1 |
Bast, A; Brauers, K; Geraets, L; Gottschalk, RW; Hageman, GJ; Moonen, HJ; Wouters, EF | 1 |
Chuang, MC; Huang, CC; Lin, CH; Lin, P; Lin, PH | 1 |
Clark, RS; Dixon, CE; Jenkins, LW; Nathaniel, PD; Szabó, C; Vagni, VA | 1 |
Adachi, T; Bessho, M; Kusuhara, M; Nishizawa, K; Ohsuzu, F; Takayama, E; Yamagishi, T; Yanagida, S | 1 |
Bezbaruah, BK; Borah, P; Gurjar, SS; Hussain, MI; Jangra, A; Lahkar, M; Mohan, P; Sriram, CS | 1 |
Areti, A; Gogoi, R; Komirishetty, P; Kumar, A; Ruby, PK; Sharma, SS; Sistla, R; Yerra, VG | 1 |
106 other study(ies) available for nad and 3-aminobenzamide
Article | Year |
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Nerve growth factor effects on pyridine nucleotides after oxidant injury of rat pheochromocytoma cells.
Topics: Animals; Benzamides; Cell Death; Coloring Agents; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; NAD; NADP; Nerve Growth Factors; Oxidation-Reduction; PC12 Cells; Poly Adenosine Diphosphate Ribose; Rats; Tetrazolium Salts; Thiazoles | 1992 |
Role of poly(ADP-ribose) formation in DNA repair.
Topics: Benzamides; Cell-Free System; DNA Damage; DNA Repair; Histones; Humans; In Vitro Techniques; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 1992 |
Metabolism of pyridine nucleotides in cultured rat hepatocytes intoxicated with tert-butyl hydroperoxide.
Topics: Animals; Benzamides; Carmustine; Cell Death; Cells, Cultured; Deferoxamine; Drug Interactions; Hydrogen Peroxide; Liver; Male; NAD; NADP; Peroxides; Phenylenediamines; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide; Time Factors | 1992 |
Inhibition of topoisomerase I by NAD and enhancement of cytotoxicity of MMS by inhibitors of poly(ADP-ribose) polymerase in Saccharomyces cerevisiae.
Topics: Benzamides; Methyl Methanesulfonate; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Saccharomyces cerevisiae; Topoisomerase I Inhibitors | 1991 |
Correlation of enhanced 6-mercaptopurine cytotoxicity with increased phosphoribosylpyrophosphate levels in Chinese hamster ovary cells treated with 3-aminobenzamide.
Topics: Animals; Azathioprine; Benzamides; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Drug Synergism; Flow Cytometry; In Vitro Techniques; Mercaptopurine; NAD; Pentosephosphates; Phosphoribosyl Pyrophosphate; Poly(ADP-ribose) Polymerase Inhibitors | 1990 |
Influence of ADP-ribosyltransferase inhibitors on the intracellular NAD and ATP levels in Ehrlich ascites tumor cells: implication for the altered NAD + ATP-dependent cellular sensitivity to the cytotoxic agents.
Topics: Adenosine Triphosphate; Animals; Azacitidine; Benzamides; Carcinoma, Ehrlich Tumor; Female; Mice; Microsomes; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide-Nucleotide Adenylyltransferase; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured | 1990 |
Lipid peroxidation, protein thiol oxidation and DNA damage in hydrogen peroxide-induced injury to endothelial cells: role of activation of poly(ADP-ribose)polymerase.
Topics: Adenosine Triphosphate; Animals; Benzamides; Cattle; Cells, Cultured; Dithiothreitol; DNA Damage; Endothelium, Vascular; Enzyme Activation; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; Lipid Peroxidation; NAD; Oxidation-Reduction; Phenylenediamines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proteins; Pulmonary Artery; Sulfhydryl Compounds; Thiobarbiturates | 1991 |
Prevention of 1,2-dibromo-3-chloropropane (DBCP)-induced kidney necrosis and testicular atrophy by 3-aminobenzamide.
Topics: Animals; Atrophy; Benzamides; DNA Damage; DNA Replication; Ethylene Dibromide; Kidney; Male; NAD; Necrosis; Poly(ADP-ribose) Polymerase Inhibitors; Propane; Rats; Testis | 1991 |
Effects of alkylating antineoplastics alone or in combination with 3-aminobenzamide on genotoxicity, antitumor activity, and NAD levels in human lymphocytes in vitro and on Ehrlich ascites tumor cells in vivo.
Topics: Alkylating Agents; Animals; Benzamides; Carcinoma, Ehrlich Tumor; DNA Damage; DNA Repair; Humans; In Vitro Techniques; Lymphocytes; Mice; Mice, Inbred BALB C; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Sister Chromatid Exchange | 1990 |
Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by calicheamicin gamma 1 in human HL-60 cells.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Benzamides; Cell Survival; DNA Damage; DNA, Neoplasm; Enediynes; Humans; Leukemia, Promyelocytic, Acute; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tumor Cells, Cultured | 1990 |
Cellular NAD+ and ATP levels in alkylation-induced cytotoxicity enhanced by an inhibitor of poly(ADP-ribose) synthesis.
Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Survival; Cells, Cultured; Cricetinae; Fibroblasts; Intracellular Fluid; Kinetics; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors | 1990 |
A comparative study on the effect of tumor promoters on poly ADP-ribosylation in A431 cells.
Topics: Benzamides; Calcium; Carcinogens; Carcinoma, Squamous Cell; DNA; Gene Expression Regulation, Enzymologic; Humans; In Vitro Techniques; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tetradecanoylphorbol Acetate | 1990 |
Relationship between poly(ADP-ribose) polymerase activity and DNA synthesis in cultured hepatocytes.
Topics: Animals; Benzamides; Cells, Cultured; DNA; DNA Replication; Epidermal Growth Factor; Kinetics; Liver; Male; NAD; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains | 1990 |
Stimulation of poly(ADP-ribose) synthesis by free radicals in C3H10T1/2 cells: relationship with NAD metabolism and DNA breakage.
Topics: Alkaline Phosphatase; Animals; Benzamides; Cell Line; Chromatography, High Pressure Liquid; Clone Cells; DNA Damage; Free Radicals; Gamma Rays; Hydrogen Peroxide; Hydrogen-Ion Concentration; Mice; NAD; Nucleoside Diphosphate Sugars; Phosphoric Diester Hydrolases; Poly Adenosine Diphosphate Ribose; Superoxides; Tritium; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Pyridine nucleotide changes in hepatocytes exposed to quinones.
Topics: Animals; Benzamides; Dimethyl Sulfoxide; Liver; Male; NAD; NADP; Oxidation-Reduction; Quinones; Rats; Rats, Inbred Strains | 1990 |
Hydrogen peroxide insult in cultured mammalian cells: relationships between DNA single-strand breakage, poly(ADP-ribose) metabolism and cell killing.
Topics: Animals; Benzamides; Cell Line; Cell Survival; Cricetinae; DNA; DNA Damage; Dose-Response Relationship, Drug; Hydrogen Peroxide; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Time Factors | 1989 |
Mechanisms of endothelial cell ATP depletion after oxidant injury.
Topics: Adenosine Triphosphate; Benzamides; Cells, Cultured; DNA Damage; Endothelium, Vascular; Enzyme Activation; Glucose Oxidase; Humans; NAD; Niacinamide; Oxidation-Reduction; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Umbilical Veins; Xanthine Oxidase | 1989 |
Inability of poly-ADP-ribosylation inhibitors to protect peripheral blood lymphocytes from the toxic effects of ADA inhibition.
Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Benzamides; Colony-Forming Units Assay; Deoxyadenosines; DNA Damage; Humans; Lymphocyte Activation; Lymphocytes; NAD; Niacinamide; Nucleoside Deaminases; Pentostatin; Poly(ADP-ribose) Polymerase Inhibitors | 1989 |
Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Benzamides; Bromodeoxyuridine; Cattle; NAD; NAD+ Nucleosidase; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors | 1989 |
Calcium-activated DNA fragmentation in rat liver nuclei.
Topics: Adenosine Triphosphate; Animals; Benzamides; Calcium; Cell Nucleus; Cell Survival; DNA; DNA Damage; Electrophoresis, Agar Gel; Endodeoxyribonucleases; Imidazoles; In Vitro Techniques; Liver; Molecular Weight; NAD; Rats | 1989 |
Is Ap4A involved in DNA repair processes?
Topics: Adenine Nucleotides; Alkylation; Benzamides; Carcinoma, Hepatocellular; Dinucleoside Phosphates; DNA; DNA Repair; Hot Temperature; Kinetics; Liver Neoplasms; Methylnitronitrosoguanidine; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Biosynthesis; Tumor Cells, Cultured | 1988 |
The cytotoxicity of chrysotile asbestos fibers to pulmonary alveolar macrophages. I. Effects of inhibitors of ADP-ribosyl transferase.
Topics: Animals; Asbestos; Asbestos, Serpentine; Benzamides; beta-Galactosidase; Cell Survival; Cells, Cultured; L-Lactate Dehydrogenase; Macrophages; Male; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Pulmonary Alveoli; Rats; Rats, Inbred Strains | 1988 |
Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase.
Topics: Actin Cytoskeleton; Actins; Adenosine Triphosphate; Animals; Benzamides; Calcium; Cell Line; Cell Survival; DNA Repair; Humans; Hydrogen Peroxide; In Vitro Techniques; Lymphocytes; Macrophages; Mice; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Theophylline | 1986 |
The cell-cycle dependent and the DNA-damaging agent-induced changes of cellular NAD content and their significance.
Topics: 4-Nitroquinoline-1-oxide; Benzamides; Cell Cycle; Cell Line; DNA Damage; DNA Replication; Humans; Interphase; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 1987 |
Nicotinamide deficiency in human lymphocytes prevents the [3H]thymidine-induced adaptive response for the repair of X-ray-induced chromosomal damage.
Topics: Benzamides; DNA; DNA Repair; Humans; Lymphocytes; NAD; Niacinamide; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thymidine | 1987 |
Metabolic consequences of DNA damage: alteration in purine metabolism following poly(ADP ribosyl)ation in human T-lymphoblasts.
Topics: Adenine; Adenosine Triphosphate; Benzamides; Cell Line; Cell Survival; DNA Damage; Glycine; Humans; Methylnitronitrosoguanidine; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Purines; T-Lymphocytes | 1987 |
Pyridine nucleotide analog interference with metabolic processes in mitogen-stimulated human T lymphocytes.
Topics: 6-Aminonicotinamide; Adenosine Triphosphate; Benzamides; Carbon Dioxide; Gluconates; Glucose-6-Phosphate; Glucosephosphates; Humans; Lymphocyte Activation; NAD; NADP; Niacinamide; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Nicotinamide protects target cells from cell-mediated cytolysis.
Topics: Benzamides; Calcium; Cell Survival; Cytotoxicity, Immunologic; DNA Damage; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lymphocyte Activation; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, Immunologic; Receptors, Interleukin-2 | 1988 |
Tumor necrosis factor-mediated cytotoxicity involves ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Benzamides; Cell Line; Cell Survival; Fibroblasts; Humans; Intracellular Fluid; Kinetics; Mice; NAD; Niacinamide; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1988 |
Inhibitors of ADP-ribosyl transferase suppress the mitogenic actions exerted by tumour promoters, but not those evoked by peptide mitogens, in primary neonatal rat hepatocytes.
Topics: Animals; Animals, Newborn; Benzamides; Carcinogens; Cell Cycle; Cell Nucleus; DNA; Epidermal Growth Factor; In Vitro Techniques; Liver; Mitogens; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Tetradecanoylphorbol Acetate | 1988 |
Similar sensitivity of human lymphoblast cells proficient or deficient in nucleotide biosynthesis to the cytotoxic and cell cycle effects of 3-aminobenzamide.
Topics: Aminobenzoates; Benzamides; Cell Cycle; Cell Line; Cell Survival; Humans; Hypoxanthine; Hypoxanthines; Lymphocytes; meta-Aminobenzoates; NAD; NAD+ Nucleosidase; Niacinamide; Nucleotides; Poly(ADP-ribose) Polymerase Inhibitors; Thymidine | 1985 |
Tumor promoter phorbol-12-myristate-13-acetate induces poly ADP-ribosylation in human monocytes.
Topics: Antioxidants; Benzamides; DNA; Humans; In Vitro Techniques; Monocytes; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Phorbols; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Tetradecanoylphorbol Acetate | 1985 |
NAD and the synthesis of (ADP-ribose)n in a human cell strain (46BR) hypersensitive to the lethal effects of 3-aminobenzamide.
Topics: Adenosine Diphosphate Ribose; Benzamides; Cell Line; Cell Survival; Humans; Immunologic Deficiency Syndromes; In Vitro Techniques; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases | 1985 |
Poly(ADP-ribose) and the recovery from damage in Chinese hamster cells due to 5-bromodeoxyuridine photolysis.
Topics: Animals; Benzamides; Bromodeoxyuridine; Cell Line; Cell Survival; Cricetinae; DNA; DNA Repair; Fibroblasts; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Photolysis; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Ultraviolet Rays | 1985 |
Specificity of inhibitors of poly(ADP-ribose) synthesis. Effects on nucleotide metabolism in cultured cells.
Topics: Animals; Benzamides; Cell Division; Cricetinae; Deoxyribonucleotides; DNA; Methylnitrosourea; Mice; NAD; NAD+ Nucleosidase; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Ribonucleotides | 1985 |
A gel-electrophoretic analysis of protein ADP-ribosylation in polyoma virus-transformed and non-transformed BHK-21/C13 fibroblasts.
Topics: Adenosine Diphosphate Ribose; Animals; Benzamides; Cell Line; Cell Membrane Permeability; Cell Transformation, Viral; Cricetinae; Electrophoresis, Polyacrylamide Gel; Fibroblasts; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Polyomavirus; Proteins; Solubility | 1986 |
ADPribosylation of nuclear proteins labeled with [3H]adenosine: changes during the HeLa cycle.
Topics: Adenosine; Adenosine Diphosphate Ribose; Benzamides; Cell Cycle; Cell Nucleus; Chromosomal Proteins, Non-Histone; HeLa Cells; Histones; Humans; Interphase; Lamins; Metaphase; NAD; Nucleoproteins; Phosphoric Diester Hydrolases | 1987 |
Relationship between DNA strand breaks and inhibition of poly (ADP-ribosylation): enhancement of carcinogen-induced transformation.
Topics: Animals; Base Sequence; Benzamides; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA, Neoplasm; Methylnitronitrosoguanidine; Mice; NAD; Oncogenes; Poly(ADP-ribose) Polymerase Inhibitors | 1986 |
Alterations in deoxynucleoside triphosphate metabolism in DNA damaged cells: identification and consequences of poly(ADP-ribose) polymerase dependent and independent processes.
Topics: Animals; Benzamides; Cell Line; Deoxyribonucleotides; DNA; DNA Repair; Enzyme Activation; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 1986 |
Chilling followed by incubation at 37 degrees C causes a reduction in NAD+ levels which can be prevented by the poly(ADP-ribose)transferase inhibitor 3-aminobenzamide.
Topics: Animals; Benzamides; Body Temperature; Cells, Cultured; Cold Temperature; Cricetinae; Cricetulus; DNA Repair; Female; NAD; Ovary; Poly(ADP-ribose) Polymerase Inhibitors | 1986 |
[The cell cycle dependent and the DNA-damaging agent-induced changes of cellular NAD content and their significance].
Topics: Amnion; Benzamides; Cell Cycle; DNA; DNA Damage; Humans; NAD; Poly(ADP-ribose) Polymerase Inhibitors | 1987 |
Synergistic enhancement of 6-thioguanine cytotoxicity by ADP-ribosyltransferase inhibitors.
Topics: Animals; Benzamides; Cell Cycle; Cell Line; Cell Survival; DNA Repair; Drug Synergism; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Thioguanine | 1988 |
NAD+ depletion and cytotoxicity in isolated hepatocytes.
Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Survival; DNA Damage; In Vitro Techniques; Liver; Male; NAD; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains; Vitamin K | 1988 |
Preventive effect of 3-aminobenzamide on the reduction of NAD levels in rat liver following administration of diethylnitrosamine.
Topics: Animals; Benzamides; Diethylnitrosamine; DNA Repair; Liver; Liver Neoplasms, Experimental; Male; NAD; Poly Adenosine Diphosphate Ribose; Rats; Rats, Inbred F344 | 1988 |
Inhibition of repair patch ligation by an inhibitor of poly(ADP-ribose) synthesis in normal human fibroblasts damaged with ultraviolet radiation.
Topics: Adenosine Triphosphate; Benzamides; Cells, Cultured; DNA Damage; DNA Repair; Fibroblasts; Humans; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Ultraviolet Rays | 1988 |
Poly(ADP-ribose) biosynthesis and suicidal NAD+ depletion following carcinogen exposure of mammalian cells.
Topics: Animals; Benzamides; Carcinogens; Cell Line; Cells, Cultured; DNA Repair; Liver; Methylnitronitrosoguanidine; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Rats; Sulfuric Acid Esters; Ultraviolet Rays | 1986 |
The differential cytotoxicity of RSU 1069: cell survival studies indicating interaction with DNA as a possible mode of action.
Topics: Animals; Benzamides; Bromodeoxyuridine; Cell Survival; Cells, Cultured; Cricetinae; DNA; Dose-Response Relationship, Drug; Glutathione; Misonidazole; NAD; Oxygen; Radiation-Sensitizing Agents | 1986 |
Sulfur mustard lowers nicotinamide adenine dinucleotide concentrations in human skin grafted to athymic nude mice.
Topics: Animals; Benzamides; Biopsy; Dose-Response Relationship, Drug; Humans; Mice; Mice, Nude; Mustard Compounds; Mustard Gas; NAD; Poly(ADP-ribose) Polymerases; Rats; Skin; Skin Transplantation; Transplantation, Heterologous | 1985 |
A 3-aminobenzamide-resistant labeled protein in [32P]NAD+-labeled cells.
Topics: Adenosine Triphosphate; Benzamides; Cell Membrane Permeability; Edetic Acid; Humans; Lymphocytes; Molecular Weight; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Proteins | 1985 |
Potentiation of alkylation-induced sister chromatid exchange frequency by 3-aminobenzamide is mediated by intracellular loss of NAD+.
Topics: Adenosine Triphosphate; Alkylation; Animals; Benzamides; Cell Line; Cell Membrane Permeability; Clone Cells; Cricetinae; Cricetulus; Drug Synergism; Female; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD; Ovary; Sister Chromatid Exchange | 1986 |
Variations in ADP-ribosylation of nuclear scaffold proteins during the HeLa cell cycle.
Topics: Adenine Nucleotides; Adenosine Diphosphate Ribose; Benzamides; Cell Cycle; Cell Nucleus; Dinucleoside Phosphates; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Lamins; NAD; Nucleoproteins; Nucleoside Diphosphate Sugars | 1985 |
Poly (ADP-ribose) is not involved in the rejoining of DNA breaks accumulated to high levels in u.v.-irradiated HeLa cells.
Topics: Alkylating Agents; Benzamides; Cytarabine; DNA Repair; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Hydroxyurea; Kinetics; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Sulfuric Acid Esters; Ultraviolet Rays | 1985 |
Inhibitors of poly (ADP-ribose) synthesis enhance radiation response by differentially affecting repair of potentially lethal versus sublethal damage.
Topics: Animals; Benzamides; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Time Factors | 1984 |
NAD+, ADP-ribosylation and transcription in permeabilized mammalian cells.
Topics: Animals; Benzamides; Cells, Cultured; Cricetinae; DNA-Directed RNA Polymerases; Fibroblasts; Kidney; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases; RNA Polymerase I; Transcription, Genetic | 1981 |
Evidence that poly(ADP-ribose) polymerase is involved in the loss of NAD from cultured rat liver cells.
Topics: Animals; Benzamides; Cells, Cultured; Liver; Male; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains | 1982 |
Inhibition of gamma-ray dose-rate effects by D2O and inhibitors of poly(ADP-ribose) synthetase in cultured mammalian L5178Y cells.
Topics: Animals; Benzamides; Cell Survival; Cells, Cultured; Cobalt Radioisotopes; Deuterium; Deuterium Oxide; Dose-Response Relationship, Radiation; Gamma Rays; Leukemia L5178; Leukemia, Experimental; Mice; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerase Inhibitors; Theobromine; Theophylline; Water | 1984 |
Roles of poly(ADP-ribose) synthesis in repair and replication in normal human, Cockayne syndrome, and xeroderma pigmentosum fibroblasts after UV irradiation.
Topics: Benzamides; Cockayne Syndrome; DNA Repair; DNA Replication; Dwarfism; Fibroblasts; Humans; In Vitro Techniques; Methyl Methanesulfonate; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Ultraviolet Rays; Xeroderma Pigmentosum | 1983 |
Different basal NAD levels determine opposite effects of poly(ADP-ribosyl)polymerase inhibitors on H2O2-induced apoptosis.
Topics: Apoptosis; Benzamides; Cell Death; Cell Line; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Kinetics; Monocytes; NAD; Niacinamide; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors | 1995 |
NAD depletion after in vitro exposure of murine lung slices to bleomycin.
Topics: Adenosine Triphosphate; Animals; Benzamides; Bleomycin; Dose-Response Relationship, Drug; Enzyme Activation; Female; Glucose; In Vitro Techniques; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NAD; Poly(ADP-ribose) Polymerases; Time Factors | 1993 |
Inhibition of poly(ADP-ribose) polymerase preserves surfactant synthesis after hydrogen peroxide exposure.
Topics: Adenosine Triphosphate; Animals; Benzamides; Deoxyglucose; Free Radical Scavengers; Hydrogen Peroxide; NAD; Niacinamide; Phosphatidylcholines; Poly(ADP-ribose) Polymerase Inhibitors; Pulmonary Alveoli; Pulmonary Surfactants; Rabbits | 1995 |
Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.
Topics: Animals; Benzamides; Cell Nucleus; Cells, Cultured; DNA Damage; Islets of Langerhans; Kinetics; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; NAD; Nitric Oxide; Nitroprusside; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Xanthine Oxidase | 1995 |
DNA base excision repair of 5-hydroxymethyl-2'-deoxyuridine stimulates poly(ADP-ribose) synthesis in Chinese hamster cells.
Topics: Animals; Antineoplastic Agents; Benzamides; Bromodeoxyuridine; Carcinogens; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA Repair; Kinetics; Methylnitronitrosoguanidine; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Thymidine; Time Factors | 1995 |
Effect of inhibitors of poly(ADP-ribose) polymerase on the induction of GRP78 and subsequent development of resistance to etoposide.
Topics: 6-Aminonicotinamide; Animals; Benzamides; Carrier Proteins; Cricetinae; Cricetulus; Drug Resistance; Endoplasmic Reticulum Chaperone BiP; Etoposide; Heat-Shock Proteins; Isoquinolines; Molecular Chaperones; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Substance Withdrawal Syndrome; Transcription, Genetic | 1995 |
Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD+ depletion.
Topics: 1-Naphthylamine; Animals; Benzamides; Cell Survival; Cells, Cultured; DNA Damage; Enzyme Activation; Islets of Langerhans; Kinetics; NAD; Naphthalimides; Niacinamide; Nitric Oxide; Penicillamine; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Time Factors | 1994 |
Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis.
Topics: Apoptosis; Benzamides; Cell Line; DNA Damage; Hot Temperature; Humans; In Vitro Techniques; NAD; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Stress, Physiological | 1994 |
Cytotoxic mechanisms of 5-fluoropyrimidines. Relationships with poly(ADP-ribose) polymerase activity, DNA strand breakage and incorporation into nucleic acids.
Topics: Animals; Benzamides; CHO Cells; Colony-Forming Units Assay; Cricetinae; Cricetulus; DNA Damage; Floxuridine; Fluorouracil; NAD; Nucleic Acids; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 1993 |
Differing effects of the inhibition of poly(ADP-ribose) polymerase on the course of oxidative cell injury in hepatocytes and fibroblasts.
Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Death; Cells, Cultured; DNA Damage; DNA, Single-Stranded; Hydrogen Peroxide; L Cells; Liver; Male; Mice; NAD; Oxidation-Reduction; Peroxides; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Time Factors | 1993 |
3-aminobenzamide protects the mouse thymocytes in vitro from dexamethasone-mediated apoptotic cell death and cytolysis without changing DNA strand breakage.
Topics: Animals; Benzamides; Cell Death; Cell Survival; Dexamethasone; DNA; DNA Damage; L-Lactate Dehydrogenase; Male; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Thymus Gland | 1993 |
Transcription of mouse ribosomal RNA gene with inactive extracts is activated by NAD+ in vitro.
Topics: Animals; Base Sequence; Benzamides; Cell Line; DNA, Ribosomal; Down-Regulation; Mice; NAD; Promoter Regions, Genetic; RNA, Ribosomal; Transcription, Genetic | 1993 |
Activation of poly(ADP-ribose)polymerase in apoptotic human cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Benzamides; Cell Nucleus; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Etoposide; HeLa Cells; Humans; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 1995 |
Changes in patterns of ADP-ribosylated proteins during differentiation of Streptomyces coelicolor A3(2) and its development mutants.
Topics: Adenosine Diphosphate; Benzamides; Chromosome Mapping; Drug Resistance, Microbial; Mutation; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Streptomyces | 1996 |
Homocysteine mediated endothelial cell toxicity and its amelioration.
Topics: Benzamides; Cell Survival; Cells, Cultured; DNA; DNA Replication; Eicosanoids; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; Homocysteine; Humans; NAD; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Sulfhydryl Compounds; Umbilical Veins; Xanthine Oxidase | 1996 |
The expression of poly(ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex.
Topics: 3T3 Cells; Animals; Benzamides; Cell Cycle; Cell Differentiation; DNA Polymerase III; DNA Primase; DNA Replication; Enzyme Induction; Flow Cytometry; HeLa Cells; Humans; Mice; Microscopy, Confocal; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; RNA Nucleotidyltransferases; RNA, Antisense; S Phase | 1996 |
Increased sensitivity to oxidative injury in chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Benzamides; Cell Survival; CHO Cells; Cricetinae; DNA Methylation; DNA Primers; DNA, Complementary; Enzyme Inhibitors; Hydrogen Peroxide; Liver; Methionine Adenosyltransferase; NAD; Oxidants; Phenylenediamines; Polymerase Chain Reaction; Rats; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Transfection | 1996 |
Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.
Topics: Animals; Benzamides; Brain; Brain Damage, Chronic; Brain Ischemia; Cerebral Infarction; DNA Damage; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Male; Mice; Mice, Inbred Strains; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases | 1997 |
Peroxynitrate-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a nonseptic shock model induced by zymosan in the rat.
Topics: Animals; Benzamides; Disease Models, Animal; DNA Damage; Energy Metabolism; Enzyme Activation; Macrophages, Peritoneal; Male; Mitochondria; NAD; NG-Nitroarginine Methyl Ester; Niacinamide; Nitrates; Nitric Oxide Synthase; Oxidants; Oxygen Consumption; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Shock; Zymosan | 1998 |
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Ankyrins; Benzamides; Catalytic Domain; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Humans; Molecular Sequence Data; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Structure, Secondary; Recombinant Proteins; Repetitive Sequences, Amino Acid; Sequence Alignment; Sequence Homology, Amino Acid; Tankyrases; Telomere; Telomeric Repeat Binding Protein 1 | 1998 |
The involvement of poly(ADP-ribose) polymerase in the oxidative stress responses in plants.
Topics: Apoptosis; Arabidopsis; Benzamides; Blotting, Western; Calcium; Cells, Cultured; DNA Repair; Glycine max; Hydrogen Peroxide; In Situ Nick-End Labeling; Ionophores; NAD; Niacinamide; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; RNA, Antisense; Time Factors; Transformation, Genetic | 1998 |
Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca2+ chelation: involvement of a common mechanism.
Topics: Adenosine Triphosphate; Benzamides; Caco-2 Cells; Calcium; Cell Death; Chelating Agents; DNA Damage; DNA, Neoplasm; Egtazic Acid; Glutathione; Humans; Hydrogen Peroxide; Kinetics; NAD; Naphthoquinones; Oxidants; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Vitamin K | 1999 |
Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Caspases; Cell Survival; Colorectal Neoplasms; Dihydroxyacetone Phosphate; Doxorubicin; Fructosediphosphates; Glycerophosphates; Humans; Iodoacetates; Leukemia L1210; Magnetic Resonance Spectroscopy; Mechlorethamine; NAD; Niacinamide; Tumor Cells, Cultured | 1999 |
Evidence for increased de novo synthesis of NAD in immune-activated RAW264.7 macrophages: a self-protective mechanism?
Topics: Animals; Benzamides; Cell Line; Dexamethasone; Enzyme Inhibitors; Interferon-gamma; Macrophage Activation; Macrophages; Mice; NAD; NG-Nitroarginine Methyl Ester; Niacinamide; Nitric Oxide Synthase; Poly(ADP-ribose) Polymerase Inhibitors; Quinolinic Acid; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase | 1999 |
Effects of nicotinamide-related agents on the growth of primary rat hepatocytes and formation of small hepatocyte colonies.
Topics: Albumins; Animals; Benzamides; Blotting, Northern; Bromodeoxyuridine; Cell Count; Cell Division; Cells, Cultured; Connexins; Enzyme Inhibitors; Gap Junction beta-1 Protein; Liver; Male; NAD; Niacin; Poly(ADP-ribose) Polymerase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tryptophan Oxygenase | 1999 |
Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia.
Topics: Animals; Benzamides; Blotting, Northern; Blotting, Western; Cell Death; Cell Survival; Disease Models, Animal; DNA Repair; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hippocampus; Immunohistochemistry; In Situ Hybridization; Ischemic Attack, Transient; Male; NAD; Neurons; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stroke | 2000 |
A scintillation proximity assay for poly(ADP-ribose) polymerase.
Topics: Animals; Autoradiography; Benzamides; Biotinylation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunoblotting; Inhibitory Concentration 50; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Scintillation Counting; Time Factors | 2000 |
IDO induction in IFN-gamma activated astroglia: a role in improving cell viability during oxidative stress.
Topics: Astrocytes; Astrocytoma; Benzamides; Cell Survival; Enzyme Induction; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; NAD; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured | 2000 |
Depletion of intracellular NAD(+) and ATP levels during ricin-induced apoptosis through the specific ribosomal inactivation results in the cytolysis of U937 cells.
Topics: Adenosine Triphosphate; Apoptosis; Benzamides; Blotting, Western; Cells, Cultured; Diphtheria Toxin; Humans; Microscopy, Fluorescence; NAD; Plant Proteins; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Ribosomes; Ricin; Time Factors; U937 Cells | 2000 |
Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity.
Topics: Animals; Apoptosis; Benzamides; Calcium; Cells, Cultured; DNA; DNA Damage; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Homocysteine; Intracellular Fluid; Kainic Acid; Membrane Potentials; Mitochondria; NAD; Neurons; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Tumor Suppressor Protein p53 | 2000 |
Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase.
Topics: Animals; Benzamides; Enzyme Inhibitors; Immunohistochemistry; Interleukin-10; Interleukin-12; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Knockout; Myocardial Reperfusion Injury; Myocardium; NAD; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Tissue Extracts; Tumor Necrosis Factor-alpha; Tyrosine | 2001 |
Different effects of tert-butylhydroperoxide-induced peroxynitrite-dependent and -independent DNA single-strand breakage on PC12 cell poly(ADP-ribose) polymerase activity.
Topics: Animals; Benzamides; Cattle; CHO Cells; Cricetinae; DNA Damage; DNA Repair; DNA, Single-Stranded; Enzyme Activation; Humans; NAD; NG-Nitroarginine Methyl Ester; PC12 Cells; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Rats; tert-Butylhydroperoxide; Time Factors; U937 Cells | 2001 |
The inhibition of poly(ADP-ribose) polymerase enhances growth rates of ataxia telangiectasia cells.
Topics: Adenosine Triphosphate; Ataxia Telangiectasia; Benzamides; Blotting, Western; Cell Division; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Humans; Isoquinolines; NAD; Poly(ADP-ribose) Polymerase Inhibitors | 2002 |
Poly(ADP-ribose) polymerase inhibition prevents both apoptotic-like delayed neuronal death and necrosis after H(2)O(2) injury.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzamides; Caspase 3; Caspases; Cell Death; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; NAD; NADP; Necrosis; Neurons; Neuroprotective Agents; PC12 Cells; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats | 2002 |
Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes.
Topics: Animals; Apoptosis; Benzamides; Caspase 3; Caspases; Cytochrome c Group; Mitochondria; Myocytes, Cardiac; NAD; Necrosis; Nitric Oxide; Oligopeptides; Rats; Rats, Sprague-Dawley; Triazenes | 2002 |
Beneficial effects of poly (ADP-ribose) polymerase inhibition against the reperfusion injury in heart transplantation.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzamides; Blotting, Western; Caspase 3; Caspases; Cell Nucleus; Creatine Kinase; DNA Damage; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Heart Transplantation; L-Lactate Dehydrogenase; Lipid Peroxidation; Myocardium; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Reperfusion Injury; Temperature; Troponin I | 2003 |
Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time.
Topics: Animals; Benzamides; CHO Cells; Comet Assay; Cricetinae; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Single-Stranded; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genotype; Isoquinolines; Methyl Methanesulfonate; Mutation; NAD; NADP; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Time Factors; X-ray Repair Cross Complementing Protein 1 | 2003 |
Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.
Topics: 1-Naphthylamine; Adenosine Triphosphate; Alkylating Agents; Apoptosis; Benzamides; Cell Death; Cell Line, Tumor; Cell Size; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia; Melphalan; Methylnitronitrosoguanidine; NAD; Naphthalimides; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones | 2003 |
Prevention of myocardial reperfusion injury by poly(ADP-ribose) synthetase inhibitor, 3-aminobenzamide, in cardioplegic solution: in vitro study of isolated rat heart model.
Topics: Animals; Apoptosis; Benzamides; Cardiac Surgical Procedures; Cardioplegic Solutions; Disease Models, Animal; DNA; Enzyme Inhibitors; Heart; Heart Arrest, Induced; Male; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Myocardium; NAD; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Time Factors; Ventricular Function, Left | 2004 |
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.
Topics: 3T3 Cells; Animals; Axons; Axotomy; Benzamides; Cell Line; Cell Nucleus; Cell Survival; Cells, Cultured; Ganglia, Spinal; Humans; Lentivirus; Mice; Mutation; NAD; Naphthols; Nerve Tissue Proteins; Neuroprotective Agents; Nicotinamide-Nucleotide Adenylyltransferase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Resveratrol; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stilbenes; Ubiquitin-Protein Ligases; Vincristine; Wallerian Degeneration | 2004 |
MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.
Topics: Antioxidants; Benzamides; Cells, Cultured; Enzyme Inhibitors; Homeodomain Proteins; Insulin; Insulin-Secreting Cells; Isoquinolines; Maf Transcription Factors, Large; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Promoter Regions, Genetic; RNA, Messenger; Trans-Activators | 2006 |
The involvement of ATP produced via (ADP-Ribose)n in the maintenance of DNA replication apparatus during DNA repair.
Topics: Adenosine Triphosphate; Benzamides; Cell Nucleus; Chromatography, High Pressure Liquid; Chromosomal Proteins, Non-Histone; Diphosphates; DNA Damage; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoside Hydrolases; HeLa Cells; Humans; Hydrolyzable Tannins; Methylnitronitrosoguanidine; Models, Biological; NAD; Poly Adenosine Diphosphate Ribose; S Phase; Thymidine Monophosphate | 2007 |
Xanthomonas caspase displays an inherent PARP-like activity.
Topics: Amidohydrolases; Amino Acid Sequence; Bacterial Proteins; Benzamides; Blotting, Western; Caspases; Cell Death; Cloning, Molecular; Cross Reactions; Culture Media; Enzyme Inhibitors; Immunoprecipitation; Molecular Sequence Data; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Structure, Tertiary; Sequence Alignment; Xanthomonas campestris | 2007 |
Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression.
Topics: Alcohol Oxidoreductases; Antioxidants; Benzamides; Cell Line, Tumor; Cell Nucleus; Cyclic N-Oxides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferrous Compounds; Flavones; Flavonoids; Gene Expression Regulation; Humans; Hydrogen Peroxide; Interleukin-8; Lipopolysaccharides; Methylnitronitrosoguanidine; Molecular Structure; NAD; NF-kappa B; Nucleotidases; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; Spin Trapping; Transcription, Genetic | 2007 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
Topics: Benzamides; Benzoflavones; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Survival; Coumarins; DNA Breaks; Environmental Pollutants; Estrogen Receptor alpha; Glutathione; Humans; NAD; NADP; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Tamoxifen | 2007 |
Local administration of the poly(ADP-ribose) polymerase inhibitor INO-1001 prevents NAD+ depletion and improves water maze performance after traumatic brain injury in mice.
Topics: Animals; Brain Injuries; Indoles; Injections, Intralesional; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; NAD; Poly(ADP-ribose) Polymerase Inhibitors | 2007 |
Continuous inhibition of poly(ADP-ribose) polymerase does not reduce reperfusion injury in isolated rat heart.
Topics: Animals; Apoptosis; Benzamides; Blotting, Western; Cardiotonic Agents; Enzyme Inhibitors; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NAD; Oncogene Protein v-akt; Phosphocreatine; Phosphorus; Phosphorylation; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Sodium; Sodium Radioisotopes; Treatment Failure; Ventricular Function, Left | 2013 |
Poly (ADP-ribose) polymerase-1 inhibitor, 3-aminobenzamide pretreatment ameliorates lipopolysaccharide-induced neurobehavioral and neurochemical anomalies in mice.
Topics: Animals; Benzamides; Catalase; Glutathione; Hippocampus; Imipramine; Immobility Response, Tonic; Interleukin-1beta; Lipid Peroxidation; Lipopolysaccharides; Male; Mice; Motor Activity; NAD; Nitrites; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2015 |
PARP inhibition attenuates neuroinflammation and oxidative stress in chronic constriction injury induced peripheral neuropathy.
Topics: Animals; Benzamides; Constriction, Pathologic; Cyclooxygenase 2; Hyperalgesia; Inflammation; Male; NAD; Neuritis; Neuroprotective Agents; Oxidative Stress; Pain Measurement; Peripheral Nervous System Diseases; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Sensation; Tyrosine; Walking | 2016 |