Page last updated: 2024-08-17

nad and 3-aminobenzamide

nad has been researched along with 3-aminobenzamide in 106 studies

Research

Studies (106)

TimeframeStudies, this research(%)All Research%
pre-199042 (39.62)18.7374
1990's40 (37.74)18.2507
2000's21 (19.81)29.6817
2010's3 (2.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ezell, EL; Jackson, GR; Perez-Polo, JR; Post, JF; Werrbach-Perez, K1
Lindahl, T; Satoh, MS1
Farber, JL; Yamamoto, K1
Choi, HS; Han, DM; Kim, WJ; Park, JK; Park, SD; Park, YS; Yu, JE1
Durkacz, BW; Harris, AL; Moses, K; Willmore, E1
Drevenstedt, B; Hoshino, J; Kröger, H; Schalge, S1
Kirkland, JB1
Brunborg, G; Dybing, E; Holme, JA; Låg, M; Søderlund, J1
Catsoulacos, P; Dozi-Vassiliades, J; Mioglou, E; Mourelatos, D; Petrou, C1
Konno, S; Oronsky, AL; Wu, JM; Zhao, B1
Ben-Hur, E; Elkind, MM; Shibuya, ML; Wells, RL1
Singh, N1
Cesarone, CF; Gallo, G; Giannoni, P; Orunesu, M; Scarabelli, L1
Alaoui Jamali, MA; Boudreau, A; Castonguay, A; Lautier, D; Poirier, D; Poirier, G1
Cohen, GM; Stubberfield, CR2
Cantoni, O; Cattabeni, F; Cerutti, P; Meyn, RE; Murray, D; Stocchi, V1
Andreoli, SP1
Ganeshaguru, K; Hoffbrand, AV; Latini, L; Piga, A1
Benjamin, RC; Jacobson, EL; Jacobson, MK; Moss, J; Rankin, PW1
Jones, DP; McConkey, DJ; Nicotera, P; Orrenius, S1
Ebel, JP; Gilson, G; Remy, P1
Lane, DA; Nadeau, D1
Cochrane, CG; Hinshaw, DB; Hyslop, PA; Schraufstatter, IU; Sklar, LA; Spragg, RG1
Chen, XR; Dai, YF; Yu, YN2
Wiencke, JK1
Barankiewicz, J; Cohen, A1
Berger, NA; Berger, SJ; Krothapalli, D; Manory, I; Sudar, DC1
Hayward, AR; Herberger, M1
Agarwal, S; Drysdale, BE; Shin, HS1
Armato, U; Menapace, L; Romano, F1
Schwartz, JL; Weichselbaum, RR1
Cerutti, P; Poirier, G; Singh, N1
Arlett, CF; James, MR; Lehmann, AR; Poirier, V1
Ben-Hur, E; Elkind, MM; Lindquist, K1
Gowans, BJ; Henderson, JF; Hunting, DJ1
Gaal, JC; Pearson, CK1
Adolph, KW1
Dritschilo, A; Kasid, UN; Lubet, RA; Smulson, ME; Stefanik, DF1
Berger, NA; Das, SK1
Cantoni, O; Cattabeni, F; Sestili, P; Stocchi, V1
Durkacz, BW; Harris, AL; Moses, K1
Emi, Y; Fujiwara, K; Konishi, Y; Nakae, D; Ohnishi, T; Shiraiwa, K; Takahashi, S; Tsutsumi, M; Uchida, K; Ueda, K1
Gowans, BJ; Hunting, DJ1
Althaus, FR; Alvarez-Gonzalez, R; Eichenberger, R1
Silver, AR; Stratford, IJ; Walling, JM1
Brinkley, FB; Gross, CL; Johnson, JB; Meier, HL; Papirmeister, B1
Berger, NA; Surowy, CS1
Schwartz, JL1
Adolph, KW; Song, MK1
Collins, A1
Ben-Hur, E; Elkind, MM; Utsumi, H1
Pearson, CK; Walker, J1
Allen, CM; Durkacz, BW; Paine, AJ; Shall, S1
Matsudaira, H; Tanaka, O; Ueno, AM1
Fujiwara, Y; Goto, K; Ichihashi, M; Yamamoto, K1
Coppola, S; Ghibelli, L; Maresca, V; Nosseri, C1
Hoyt, DG; Lazo, JS1
Holm, BA; Hudak, BB; Maloney, C; Sokolowski, J; Tufariello, J1
Burkart, V; Bürkle, A; Fehsel, K; Heller, B; Kolb, H; Radons, J; Wagner, EF; Wang, ZQ1
Boorstein, RJ; Haldar, J; Poirier, G; Putnam, D1
Berger, NA; Berger, RB; Berger, SJ; Chatterjee, S; Cheng, MF1
Burkart, V; Bürkle, A; Hartmann, B; Heller, B; Kolb, H; Kröncke, KD; Radons, J; Rodriguez, ML1
Coppola, S; Ghibelli, L; Nosseri, C1
Durkacz, BW; Willmore, E1
Farber, JL; Tsukidate, K; Yamamoto, K1
Beckmann, G; Hoshino, J; Kröger, H1
Kominami, R; Mishima, Y; Muramatsu, M; Nishimura, T1
Bernardi, R; Donzelli, M; Guano, F; Negri, C; Prosperi, E; Scovassi, AI; Torti, M1
Ochi, K; Penyige, A; Shima, J1
Blundell, G; Jones, BG; Rose, FA; Tudball, N1
Applegren, N; Bers, G; Hickey, R; Hilz, H; Malkas, L; Rosenthal, DS; Simbulan-Rosenthal, CM; Smulson, ME; Wu, Y1
Alvarez, L; Farber, JL; García, C; Mato, JM; Pajares, MA; Pastorino, JG; Sánchez-Góngora, E; Viña, JR1
Endres, M; Moskowitz, MA; Namura, S; Waeber, C; Wang, ZQ1
Caputi, AP; Cuzzocrea, S; Zingarelli, B1
de Lange, T; Giriat, I; Schmitt, A; Smith, S1
Amor, Y; Babiychuk, E; Inzé, D; Levine, A1
Karczewski, JM; Noordhoek, J; Peters, JG1
Al-Saffar, NM; Clarke, PA; Cunningham, DC; DiStefano, F; Griffiths, JR; Leach, MO; McCoy, CL; Robertson, D; Ronen, SM; Smith, TA; Titley, J1
Grant, RS; Kapoor, V; Matanovic, G; Passey, R; Smythe, G1
Hirata, K; Mitaka, T; Mizuguchi, T; Mochizuki, Y; Sato, F1
Chen, D; Chen, J; Henshall, DC; Nagayama, T; Pei, W; Simon, RP; Stetler, RA1
Cheung, A; Zhang, J1
Espinosa, M; Grant, RS; Kapoor, V; Naif, H1
Komatsu, N; Muramatsu, T; Nakagawa, M; Oda, T1
Chan, SL; Culmsee, C; Guo, Z; Kruman, II; Kruman, Y; Mattson, MP; Penix, L1
Al-Affar, EB; Liaudet, L; Szabó, C; Yang, Z1
Cantoni, O; Guidarelli, A; Palomba, L; Scovassi, AI1
Marecki, JC; McCord, JM1
Cole, KK; Perez-Polo, JR1
Imamura, H; Kido, M; Kobayashi, Y; Ninomiya, H; Nogi, S; Okada, T; Otani, H; Uchiyama, T1
Cecchi, C; Celli, A; Fiorillo, C; Formigli, L; Giannini, L; Liguori, P; Nassi, N; Nassi, P; Nediani, C; Perna, AM; Ponziani, V; Tani, A1
Asakura, S; Caldecott, KW; de Murcia, G; Hester, SD; Nakamura, J; Swenberg, JA1
Hasmann, M; Nüssler, V; Pelka-Fleischer, R; Pogrebniak, A; Schemainda, I1
Komeda, M; Miwa, S; Nishimura, K; Tanaka, S; Toyokuni, S; Ueda, K; Unimonh, O; Yamazaki, K1
Araki, T; Milbrandt, J; Sasaki, Y1
Linning, KD; Olson, LK; Szabo, C; Tai, MH; Ye, DZ1
Hatano, T; Maruta, H; Okita, N; Takasawa, R; Tanuma, S; Uchiumi, F1
Misra, HS; Raju, KK; Sharma, A1
Bast, A; Brauers, K; Geraets, L; Gottschalk, RW; Hageman, GJ; Moonen, HJ; Wouters, EF1
Chuang, MC; Huang, CC; Lin, CH; Lin, P; Lin, PH1
Clark, RS; Dixon, CE; Jenkins, LW; Nathaniel, PD; Szabó, C; Vagni, VA1
Adachi, T; Bessho, M; Kusuhara, M; Nishizawa, K; Ohsuzu, F; Takayama, E; Yamagishi, T; Yanagida, S1
Bezbaruah, BK; Borah, P; Gurjar, SS; Hussain, MI; Jangra, A; Lahkar, M; Mohan, P; Sriram, CS1
Areti, A; Gogoi, R; Komirishetty, P; Kumar, A; Ruby, PK; Sharma, SS; Sistla, R; Yerra, VG1

Other Studies

106 other study(ies) available for nad and 3-aminobenzamide

ArticleYear
Nerve growth factor effects on pyridine nucleotides after oxidant injury of rat pheochromocytoma cells.
    Brain research, 1992, Oct-02, Volume: 592, Issue:1-2

    Topics: Animals; Benzamides; Cell Death; Coloring Agents; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; NAD; NADP; Nerve Growth Factors; Oxidation-Reduction; PC12 Cells; Poly Adenosine Diphosphate Ribose; Rats; Tetrazolium Salts; Thiazoles

1992
Role of poly(ADP-ribose) formation in DNA repair.
    Nature, 1992, Mar-26, Volume: 356, Issue:6367

    Topics: Benzamides; Cell-Free System; DNA Damage; DNA Repair; Histones; Humans; In Vitro Techniques; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

1992
Metabolism of pyridine nucleotides in cultured rat hepatocytes intoxicated with tert-butyl hydroperoxide.
    Biochemical pharmacology, 1992, Mar-03, Volume: 43, Issue:5

    Topics: Animals; Benzamides; Carmustine; Cell Death; Cells, Cultured; Deferoxamine; Drug Interactions; Hydrogen Peroxide; Liver; Male; NAD; NADP; Peroxides; Phenylenediamines; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide; Time Factors

1992
Inhibition of topoisomerase I by NAD and enhancement of cytotoxicity of MMS by inhibitors of poly(ADP-ribose) polymerase in Saccharomyces cerevisiae.
    Cellular and molecular biology, 1991, Volume: 37, Issue:7

    Topics: Benzamides; Methyl Methanesulfonate; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Saccharomyces cerevisiae; Topoisomerase I Inhibitors

1991
Correlation of enhanced 6-mercaptopurine cytotoxicity with increased phosphoribosylpyrophosphate levels in Chinese hamster ovary cells treated with 3-aminobenzamide.
    Cancer research, 1990, Apr-01, Volume: 50, Issue:7

    Topics: Animals; Azathioprine; Benzamides; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Drug Synergism; Flow Cytometry; In Vitro Techniques; Mercaptopurine; NAD; Pentosephosphates; Phosphoribosyl Pyrophosphate; Poly(ADP-ribose) Polymerase Inhibitors

1990
Influence of ADP-ribosyltransferase inhibitors on the intracellular NAD and ATP levels in Ehrlich ascites tumor cells: implication for the altered NAD + ATP-dependent cellular sensitivity to the cytotoxic agents.
    Biochemistry international, 1990, Volume: 20, Issue:1

    Topics: Adenosine Triphosphate; Animals; Azacitidine; Benzamides; Carcinoma, Ehrlich Tumor; Female; Mice; Microsomes; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide-Nucleotide Adenylyltransferase; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured

1990
Lipid peroxidation, protein thiol oxidation and DNA damage in hydrogen peroxide-induced injury to endothelial cells: role of activation of poly(ADP-ribose)polymerase.
    Biochimica et biophysica acta, 1991, May-17, Volume: 1092, Issue:3

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cattle; Cells, Cultured; Dithiothreitol; DNA Damage; Endothelium, Vascular; Enzyme Activation; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; Lipid Peroxidation; NAD; Oxidation-Reduction; Phenylenediamines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proteins; Pulmonary Artery; Sulfhydryl Compounds; Thiobarbiturates

1991
Prevention of 1,2-dibromo-3-chloropropane (DBCP)-induced kidney necrosis and testicular atrophy by 3-aminobenzamide.
    Toxicology and applied pharmacology, 1991, Volume: 110, Issue:1

    Topics: Animals; Atrophy; Benzamides; DNA Damage; DNA Replication; Ethylene Dibromide; Kidney; Male; NAD; Necrosis; Poly(ADP-ribose) Polymerase Inhibitors; Propane; Rats; Testis

1991
Effects of alkylating antineoplastics alone or in combination with 3-aminobenzamide on genotoxicity, antitumor activity, and NAD levels in human lymphocytes in vitro and on Ehrlich ascites tumor cells in vivo.
    Teratogenesis, carcinogenesis, and mutagenesis, 1990, Volume: 10, Issue:4

    Topics: Alkylating Agents; Animals; Benzamides; Carcinoma, Ehrlich Tumor; DNA Damage; DNA Repair; Humans; In Vitro Techniques; Lymphocytes; Mice; Mice, Inbred BALB C; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Sister Chromatid Exchange

1990
Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by calicheamicin gamma 1 in human HL-60 cells.
    Cancer letters, 1990, Apr-20, Volume: 50, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Benzamides; Cell Survival; DNA Damage; DNA, Neoplasm; Enediynes; Humans; Leukemia, Promyelocytic, Acute; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tumor Cells, Cultured

1990
Cellular NAD+ and ATP levels in alkylation-induced cytotoxicity enhanced by an inhibitor of poly(ADP-ribose) synthesis.
    Cancer biochemistry biophysics, 1990, Volume: 11, Issue:2

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Survival; Cells, Cultured; Cricetinae; Fibroblasts; Intracellular Fluid; Kinetics; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors

1990
A comparative study on the effect of tumor promoters on poly ADP-ribosylation in A431 cells.
    International journal of cancer, 1990, Oct-15, Volume: 46, Issue:4

    Topics: Benzamides; Calcium; Carcinogens; Carcinoma, Squamous Cell; DNA; Gene Expression Regulation, Enzymologic; Humans; In Vitro Techniques; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tetradecanoylphorbol Acetate

1990
Relationship between poly(ADP-ribose) polymerase activity and DNA synthesis in cultured hepatocytes.
    Biochemical and biophysical research communications, 1990, Sep-28, Volume: 171, Issue:3

    Topics: Animals; Benzamides; Cells, Cultured; DNA; DNA Replication; Epidermal Growth Factor; Kinetics; Liver; Male; NAD; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains

1990
Stimulation of poly(ADP-ribose) synthesis by free radicals in C3H10T1/2 cells: relationship with NAD metabolism and DNA breakage.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1990, Volume: 68, Issue:3

    Topics: Alkaline Phosphatase; Animals; Benzamides; Cell Line; Chromatography, High Pressure Liquid; Clone Cells; DNA Damage; Free Radicals; Gamma Rays; Hydrogen Peroxide; Hydrogen-Ion Concentration; Mice; NAD; Nucleoside Diphosphate Sugars; Phosphoric Diester Hydrolases; Poly Adenosine Diphosphate Ribose; Superoxides; Tritium; Xanthine; Xanthine Oxidase; Xanthines

1990
Pyridine nucleotide changes in hepatocytes exposed to quinones.
    Free radical research communications, 1990, Volume: 8, Issue:4-6

    Topics: Animals; Benzamides; Dimethyl Sulfoxide; Liver; Male; NAD; NADP; Oxidation-Reduction; Quinones; Rats; Rats, Inbred Strains

1990
Hydrogen peroxide insult in cultured mammalian cells: relationships between DNA single-strand breakage, poly(ADP-ribose) metabolism and cell killing.
    Biochimica et biophysica acta, 1989, Oct-30, Volume: 1014, Issue:1

    Topics: Animals; Benzamides; Cell Line; Cell Survival; Cricetinae; DNA; DNA Damage; Dose-Response Relationship, Drug; Hydrogen Peroxide; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Time Factors

1989
Mechanisms of endothelial cell ATP depletion after oxidant injury.
    Pediatric research, 1989, Volume: 25, Issue:1

    Topics: Adenosine Triphosphate; Benzamides; Cells, Cultured; DNA Damage; Endothelium, Vascular; Enzyme Activation; Glucose Oxidase; Humans; NAD; Niacinamide; Oxidation-Reduction; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Umbilical Veins; Xanthine Oxidase

1989
Inability of poly-ADP-ribosylation inhibitors to protect peripheral blood lymphocytes from the toxic effects of ADA inhibition.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Benzamides; Colony-Forming Units Assay; Deoxyadenosines; DNA Damage; Humans; Lymphocyte Activation; Lymphocytes; NAD; Niacinamide; Nucleoside Deaminases; Pentostatin; Poly(ADP-ribose) Polymerase Inhibitors

1989
Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo.
    The Journal of biological chemistry, 1989, Mar-15, Volume: 264, Issue:8

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Benzamides; Bromodeoxyuridine; Cattle; NAD; NAD+ Nucleosidase; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors

1989
Calcium-activated DNA fragmentation in rat liver nuclei.
    The Journal of biological chemistry, 1989, Apr-15, Volume: 264, Issue:11

    Topics: Adenosine Triphosphate; Animals; Benzamides; Calcium; Cell Nucleus; Cell Survival; DNA; DNA Damage; Electrophoresis, Agar Gel; Endodeoxyribonucleases; Imidazoles; In Vitro Techniques; Liver; Molecular Weight; NAD; Rats

1989
Is Ap4A involved in DNA repair processes?
    Experimental cell research, 1988, Volume: 177, Issue:1

    Topics: Adenine Nucleotides; Alkylation; Benzamides; Carcinoma, Hepatocellular; Dinucleoside Phosphates; DNA; DNA Repair; Hot Temperature; Kinetics; Liver Neoplasms; Methylnitronitrosoguanidine; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Biosynthesis; Tumor Cells, Cultured

1988
The cytotoxicity of chrysotile asbestos fibers to pulmonary alveolar macrophages. I. Effects of inhibitors of ADP-ribosyl transferase.
    Cell biology and toxicology, 1988, Volume: 4, Issue:1

    Topics: Animals; Asbestos; Asbestos, Serpentine; Benzamides; beta-Galactosidase; Cell Survival; Cells, Cultured; L-Lactate Dehydrogenase; Macrophages; Male; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Pulmonary Alveoli; Rats; Rats, Inbred Strains

1988
Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:13

    Topics: Actin Cytoskeleton; Actins; Adenosine Triphosphate; Animals; Benzamides; Calcium; Cell Line; Cell Survival; DNA Repair; Humans; Hydrogen Peroxide; In Vitro Techniques; Lymphocytes; Macrophages; Mice; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Theophylline

1986
The cell-cycle dependent and the DNA-damaging agent-induced changes of cellular NAD content and their significance.
    Mutation research, 1987, Volume: 191, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Benzamides; Cell Cycle; Cell Line; DNA Damage; DNA Replication; Humans; Interphase; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

1987
Nicotinamide deficiency in human lymphocytes prevents the [3H]thymidine-induced adaptive response for the repair of X-ray-induced chromosomal damage.
    Experimental cell research, 1987, Volume: 171, Issue:2

    Topics: Benzamides; DNA; DNA Repair; Humans; Lymphocytes; NAD; Niacinamide; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thymidine

1987
Metabolic consequences of DNA damage: alteration in purine metabolism following poly(ADP ribosyl)ation in human T-lymphoblasts.
    Archives of biochemistry and biophysics, 1987, Nov-01, Volume: 258, Issue:2

    Topics: Adenine; Adenosine Triphosphate; Benzamides; Cell Line; Cell Survival; DNA Damage; Glycine; Humans; Methylnitronitrosoguanidine; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Purines; T-Lymphocytes

1987
Pyridine nucleotide analog interference with metabolic processes in mitogen-stimulated human T lymphocytes.
    Experimental cell research, 1987, Volume: 173, Issue:2

    Topics: 6-Aminonicotinamide; Adenosine Triphosphate; Benzamides; Carbon Dioxide; Gluconates; Glucose-6-Phosphate; Glucosephosphates; Humans; Lymphocyte Activation; NAD; NADP; Niacinamide; T-Lymphocytes; Tetradecanoylphorbol Acetate

1987
Nicotinamide protects target cells from cell-mediated cytolysis.
    Cellular immunology, 1988, Volume: 113, Issue:2

    Topics: Benzamides; Calcium; Cell Survival; Cytotoxicity, Immunologic; DNA Damage; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lymphocyte Activation; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, Immunologic; Receptors, Interleukin-2

1988
Tumor necrosis factor-mediated cytotoxicity involves ADP-ribosylation.
    Journal of immunology (Baltimore, Md. : 1950), 1988, Jun-15, Volume: 140, Issue:12

    Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Benzamides; Cell Line; Cell Survival; Fibroblasts; Humans; Intracellular Fluid; Kinetics; Mice; NAD; Niacinamide; Recombinant Proteins; Tumor Necrosis Factor-alpha

1988
Inhibitors of ADP-ribosyl transferase suppress the mitogenic actions exerted by tumour promoters, but not those evoked by peptide mitogens, in primary neonatal rat hepatocytes.
    Carcinogenesis, 1988, Volume: 9, Issue:12

    Topics: Animals; Animals, Newborn; Benzamides; Carcinogens; Cell Cycle; Cell Nucleus; DNA; Epidermal Growth Factor; In Vitro Techniques; Liver; Mitogens; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Tetradecanoylphorbol Acetate

1988
Similar sensitivity of human lymphoblast cells proficient or deficient in nucleotide biosynthesis to the cytotoxic and cell cycle effects of 3-aminobenzamide.
    Experimental cell research, 1985, Volume: 157, Issue:1

    Topics: Aminobenzoates; Benzamides; Cell Cycle; Cell Line; Cell Survival; Humans; Hypoxanthine; Hypoxanthines; Lymphocytes; meta-Aminobenzoates; NAD; NAD+ Nucleosidase; Niacinamide; Nucleotides; Poly(ADP-ribose) Polymerase Inhibitors; Thymidine

1985
Tumor promoter phorbol-12-myristate-13-acetate induces poly ADP-ribosylation in human monocytes.
    Biochemical and biophysical research communications, 1985, Feb-15, Volume: 126, Issue:3

    Topics: Antioxidants; Benzamides; DNA; Humans; In Vitro Techniques; Monocytes; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Phorbols; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Tetradecanoylphorbol Acetate

1985
NAD and the synthesis of (ADP-ribose)n in a human cell strain (46BR) hypersensitive to the lethal effects of 3-aminobenzamide.
    Carcinogenesis, 1985, Volume: 6, Issue:6

    Topics: Adenosine Diphosphate Ribose; Benzamides; Cell Line; Cell Survival; Humans; Immunologic Deficiency Syndromes; In Vitro Techniques; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases

1985
Poly(ADP-ribose) and the recovery from damage in Chinese hamster cells due to 5-bromodeoxyuridine photolysis.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 48, Issue:1

    Topics: Animals; Benzamides; Bromodeoxyuridine; Cell Line; Cell Survival; Cricetinae; DNA; DNA Repair; Fibroblasts; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Photolysis; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Ultraviolet Rays

1985
Specificity of inhibitors of poly(ADP-ribose) synthesis. Effects on nucleotide metabolism in cultured cells.
    Molecular pharmacology, 1985, Volume: 28, Issue:2

    Topics: Animals; Benzamides; Cell Division; Cricetinae; Deoxyribonucleotides; DNA; Methylnitrosourea; Mice; NAD; NAD+ Nucleosidase; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Ribonucleotides

1985
A gel-electrophoretic analysis of protein ADP-ribosylation in polyoma virus-transformed and non-transformed BHK-21/C13 fibroblasts.
    Biochimica et biophysica acta, 1986, Apr-11, Volume: 881, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Benzamides; Cell Line; Cell Membrane Permeability; Cell Transformation, Viral; Cricetinae; Electrophoresis, Polyacrylamide Gel; Fibroblasts; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Polyomavirus; Proteins; Solubility

1986
ADPribosylation of nuclear proteins labeled with [3H]adenosine: changes during the HeLa cycle.
    Biochimica et biophysica acta, 1987, Aug-25, Volume: 909, Issue:3

    Topics: Adenosine; Adenosine Diphosphate Ribose; Benzamides; Cell Cycle; Cell Nucleus; Chromosomal Proteins, Non-Histone; HeLa Cells; Histones; Humans; Interphase; Lamins; Metaphase; NAD; Nucleoproteins; Phosphoric Diester Hydrolases

1987
Relationship between DNA strand breaks and inhibition of poly (ADP-ribosylation): enhancement of carcinogen-induced transformation.
    Carcinogenesis, 1986, Volume: 7, Issue:2

    Topics: Animals; Base Sequence; Benzamides; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA, Neoplasm; Methylnitronitrosoguanidine; Mice; NAD; Oncogenes; Poly(ADP-ribose) Polymerase Inhibitors

1986
Alterations in deoxynucleoside triphosphate metabolism in DNA damaged cells: identification and consequences of poly(ADP-ribose) polymerase dependent and independent processes.
    Biochemical and biophysical research communications, 1986, Jun-30, Volume: 137, Issue:3

    Topics: Animals; Benzamides; Cell Line; Deoxyribonucleotides; DNA; DNA Repair; Enzyme Activation; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

1986
Chilling followed by incubation at 37 degrees C causes a reduction in NAD+ levels which can be prevented by the poly(ADP-ribose)transferase inhibitor 3-aminobenzamide.
    FEBS letters, 1986, Aug-18, Volume: 204, Issue:2

    Topics: Animals; Benzamides; Body Temperature; Cells, Cultured; Cold Temperature; Cricetinae; Cricetulus; DNA Repair; Female; NAD; Ovary; Poly(ADP-ribose) Polymerase Inhibitors

1986
[The cell cycle dependent and the DNA-damaging agent-induced changes of cellular NAD content and their significance].
    Shi yan sheng wu xue bao, 1987, Volume: 20, Issue:3

    Topics: Amnion; Benzamides; Cell Cycle; DNA; DNA Damage; Humans; NAD; Poly(ADP-ribose) Polymerase Inhibitors

1987
Synergistic enhancement of 6-thioguanine cytotoxicity by ADP-ribosyltransferase inhibitors.
    Cancer research, 1988, Oct-15, Volume: 48, Issue:20

    Topics: Animals; Benzamides; Cell Cycle; Cell Line; Cell Survival; DNA Repair; Drug Synergism; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Thioguanine

1988
NAD+ depletion and cytotoxicity in isolated hepatocytes.
    Biochemical pharmacology, 1988, Oct-15, Volume: 37, Issue:20

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Survival; DNA Damage; In Vitro Techniques; Liver; Male; NAD; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains; Vitamin K

1988
Preventive effect of 3-aminobenzamide on the reduction of NAD levels in rat liver following administration of diethylnitrosamine.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:10

    Topics: Animals; Benzamides; Diethylnitrosamine; DNA Repair; Liver; Liver Neoplasms, Experimental; Male; NAD; Poly Adenosine Diphosphate Ribose; Rats; Rats, Inbred F344

1988
Inhibition of repair patch ligation by an inhibitor of poly(ADP-ribose) synthesis in normal human fibroblasts damaged with ultraviolet radiation.
    Molecular pharmacology, 1988, Volume: 33, Issue:3

    Topics: Adenosine Triphosphate; Benzamides; Cells, Cultured; DNA Damage; DNA Repair; Fibroblasts; Humans; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Ultraviolet Rays

1988
Poly(ADP-ribose) biosynthesis and suicidal NAD+ depletion following carcinogen exposure of mammalian cells.
    Biochemical and biophysical research communications, 1986, Aug-14, Volume: 138, Issue:3

    Topics: Animals; Benzamides; Carcinogens; Cell Line; Cells, Cultured; DNA Repair; Liver; Methylnitronitrosoguanidine; Mice; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Rats; Sulfuric Acid Esters; Ultraviolet Rays

1986
The differential cytotoxicity of RSU 1069: cell survival studies indicating interaction with DNA as a possible mode of action.
    British journal of cancer, 1986, Volume: 53, Issue:3

    Topics: Animals; Benzamides; Bromodeoxyuridine; Cell Survival; Cells, Cultured; Cricetinae; DNA; Dose-Response Relationship, Drug; Glutathione; Misonidazole; NAD; Oxygen; Radiation-Sensitizing Agents

1986
Sulfur mustard lowers nicotinamide adenine dinucleotide concentrations in human skin grafted to athymic nude mice.
    Toxicology and applied pharmacology, 1985, Volume: 81, Issue:1

    Topics: Animals; Benzamides; Biopsy; Dose-Response Relationship, Drug; Humans; Mice; Mice, Nude; Mustard Compounds; Mustard Gas; NAD; Poly(ADP-ribose) Polymerases; Rats; Skin; Skin Transplantation; Transplantation, Heterologous

1985
A 3-aminobenzamide-resistant labeled protein in [32P]NAD+-labeled cells.
    Biochimica et biophysica acta, 1985, Dec-12, Volume: 847, Issue:3

    Topics: Adenosine Triphosphate; Benzamides; Cell Membrane Permeability; Edetic Acid; Humans; Lymphocytes; Molecular Weight; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Proteins

1985
Potentiation of alkylation-induced sister chromatid exchange frequency by 3-aminobenzamide is mediated by intracellular loss of NAD+.
    Carcinogenesis, 1986, Volume: 7, Issue:1

    Topics: Adenosine Triphosphate; Alkylation; Animals; Benzamides; Cell Line; Cell Membrane Permeability; Clone Cells; Cricetinae; Cricetulus; Drug Synergism; Female; Methyl Methanesulfonate; Methylnitronitrosoguanidine; NAD; Ovary; Sister Chromatid Exchange

1986
Variations in ADP-ribosylation of nuclear scaffold proteins during the HeLa cell cycle.
    Biochemical and biophysical research communications, 1985, Jan-31, Volume: 126, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate Ribose; Benzamides; Cell Cycle; Cell Nucleus; Dinucleoside Phosphates; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Lamins; NAD; Nucleoproteins; Nucleoside Diphosphate Sugars

1985
Poly (ADP-ribose) is not involved in the rejoining of DNA breaks accumulated to high levels in u.v.-irradiated HeLa cells.
    Carcinogenesis, 1985, Volume: 6, Issue:7

    Topics: Alkylating Agents; Benzamides; Cytarabine; DNA Repair; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Hydroxyurea; Kinetics; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Sulfuric Acid Esters; Ultraviolet Rays

1985
Inhibitors of poly (ADP-ribose) synthesis enhance radiation response by differentially affecting repair of potentially lethal versus sublethal damage.
    The British journal of cancer. Supplement, 1984, Volume: 6

    Topics: Animals; Benzamides; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Time Factors

1984
NAD+, ADP-ribosylation and transcription in permeabilized mammalian cells.
    The Biochemical journal, 1981, Dec-01, Volume: 199, Issue:3

    Topics: Animals; Benzamides; Cells, Cultured; Cricetinae; DNA-Directed RNA Polymerases; Fibroblasts; Kidney; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases; RNA Polymerase I; Transcription, Genetic

1981
Evidence that poly(ADP-ribose) polymerase is involved in the loss of NAD from cultured rat liver cells.
    The Biochemical journal, 1982, Feb-15, Volume: 202, Issue:2

    Topics: Animals; Benzamides; Cells, Cultured; Liver; Male; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains

1982
Inhibition of gamma-ray dose-rate effects by D2O and inhibitors of poly(ADP-ribose) synthetase in cultured mammalian L5178Y cells.
    Radiation research, 1984, Volume: 98, Issue:3

    Topics: Animals; Benzamides; Cell Survival; Cells, Cultured; Cobalt Radioisotopes; Deuterium; Deuterium Oxide; Dose-Response Relationship, Radiation; Gamma Rays; Leukemia L5178; Leukemia, Experimental; Mice; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerase Inhibitors; Theobromine; Theophylline; Water

1984
Roles of poly(ADP-ribose) synthesis in repair and replication in normal human, Cockayne syndrome, and xeroderma pigmentosum fibroblasts after UV irradiation.
    Princess Takamatsu symposia, 1983, Volume: 13

    Topics: Benzamides; Cockayne Syndrome; DNA Repair; DNA Replication; Dwarfism; Fibroblasts; Humans; In Vitro Techniques; Methyl Methanesulfonate; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Ultraviolet Rays; Xeroderma Pigmentosum

1983
Different basal NAD levels determine opposite effects of poly(ADP-ribosyl)polymerase inhibitors on H2O2-induced apoptosis.
    Experimental cell research, 1995, Volume: 221, Issue:2

    Topics: Apoptosis; Benzamides; Cell Death; Cell Line; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Kinetics; Monocytes; NAD; Niacinamide; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors

1995
NAD depletion after in vitro exposure of murine lung slices to bleomycin.
    Biochemical pharmacology, 1993, Nov-17, Volume: 46, Issue:10

    Topics: Adenosine Triphosphate; Animals; Benzamides; Bleomycin; Dose-Response Relationship, Drug; Enzyme Activation; Female; Glucose; In Vitro Techniques; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NAD; Poly(ADP-ribose) Polymerases; Time Factors

1993
Inhibition of poly(ADP-ribose) polymerase preserves surfactant synthesis after hydrogen peroxide exposure.
    The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 1

    Topics: Adenosine Triphosphate; Animals; Benzamides; Deoxyglucose; Free Radical Scavengers; Hydrogen Peroxide; NAD; Niacinamide; Phosphatidylcholines; Poly(ADP-ribose) Polymerase Inhibitors; Pulmonary Alveoli; Pulmonary Surfactants; Rabbits

1995
Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.
    The Journal of biological chemistry, 1995, May-12, Volume: 270, Issue:19

    Topics: Animals; Benzamides; Cell Nucleus; Cells, Cultured; DNA Damage; Islets of Langerhans; Kinetics; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; NAD; Nitric Oxide; Nitroprusside; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Xanthine Oxidase

1995
DNA base excision repair of 5-hydroxymethyl-2'-deoxyuridine stimulates poly(ADP-ribose) synthesis in Chinese hamster cells.
    Carcinogenesis, 1995, Volume: 16, Issue:5

    Topics: Animals; Antineoplastic Agents; Benzamides; Bromodeoxyuridine; Carcinogens; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA Repair; Kinetics; Methylnitronitrosoguanidine; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Thymidine; Time Factors

1995
Effect of inhibitors of poly(ADP-ribose) polymerase on the induction of GRP78 and subsequent development of resistance to etoposide.
    Cancer research, 1995, Feb-15, Volume: 55, Issue:4

    Topics: 6-Aminonicotinamide; Animals; Benzamides; Carrier Proteins; Cricetinae; Cricetulus; Drug Resistance; Endoplasmic Reticulum Chaperone BiP; Etoposide; Heat-Shock Proteins; Isoquinolines; Molecular Chaperones; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Substance Withdrawal Syndrome; Transcription, Genetic

1995
Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD+ depletion.
    Biochemical and biophysical research communications, 1994, Mar-30, Volume: 199, Issue:3

    Topics: 1-Naphthylamine; Animals; Benzamides; Cell Survival; Cells, Cultured; DNA Damage; Enzyme Activation; Islets of Langerhans; Kinetics; NAD; Naphthalimides; Niacinamide; Nitric Oxide; Penicillamine; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Time Factors

1994
Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis.
    Experimental cell research, 1994, Volume: 212, Issue:2

    Topics: Apoptosis; Benzamides; Cell Line; DNA Damage; Hot Temperature; Humans; In Vitro Techniques; NAD; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Stress, Physiological

1994
Cytotoxic mechanisms of 5-fluoropyrimidines. Relationships with poly(ADP-ribose) polymerase activity, DNA strand breakage and incorporation into nucleic acids.
    Biochemical pharmacology, 1993, Jul-20, Volume: 46, Issue:2

    Topics: Animals; Benzamides; CHO Cells; Colony-Forming Units Assay; Cricetinae; Cricetulus; DNA Damage; Floxuridine; Fluorouracil; NAD; Nucleic Acids; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

1993
Differing effects of the inhibition of poly(ADP-ribose) polymerase on the course of oxidative cell injury in hepatocytes and fibroblasts.
    Biochemical pharmacology, 1993, Aug-03, Volume: 46, Issue:3

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Death; Cells, Cultured; DNA Damage; DNA, Single-Stranded; Hydrogen Peroxide; L Cells; Liver; Male; Mice; NAD; Oxidation-Reduction; Peroxides; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Time Factors

1993
3-aminobenzamide protects the mouse thymocytes in vitro from dexamethasone-mediated apoptotic cell death and cytolysis without changing DNA strand breakage.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:2

    Topics: Animals; Benzamides; Cell Death; Cell Survival; Dexamethasone; DNA; DNA Damage; L-Lactate Dehydrogenase; Male; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Thymus Gland

1993
Transcription of mouse ribosomal RNA gene with inactive extracts is activated by NAD+ in vitro.
    Journal of biochemistry, 1993, Volume: 113, Issue:1

    Topics: Animals; Base Sequence; Benzamides; Cell Line; DNA, Ribosomal; Down-Regulation; Mice; NAD; Promoter Regions, Genetic; RNA, Ribosomal; Transcription, Genetic

1993
Activation of poly(ADP-ribose)polymerase in apoptotic human cells.
    Biochimie, 1995, Volume: 77, Issue:5

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Benzamides; Cell Nucleus; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Etoposide; HeLa Cells; Humans; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

1995
Changes in patterns of ADP-ribosylated proteins during differentiation of Streptomyces coelicolor A3(2) and its development mutants.
    Journal of bacteriology, 1996, Volume: 178, Issue:13

    Topics: Adenosine Diphosphate; Benzamides; Chromosome Mapping; Drug Resistance, Microbial; Mutation; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Streptomyces

1996
Homocysteine mediated endothelial cell toxicity and its amelioration.
    Atherosclerosis, 1996, Volume: 122, Issue:2

    Topics: Benzamides; Cell Survival; Cells, Cultured; DNA; DNA Replication; Eicosanoids; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; Homocysteine; Humans; NAD; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Sulfhydryl Compounds; Umbilical Veins; Xanthine Oxidase

1996
The expression of poly(ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex.
    Biochemistry, 1996, Sep-10, Volume: 35, Issue:36

    Topics: 3T3 Cells; Animals; Benzamides; Cell Cycle; Cell Differentiation; DNA Polymerase III; DNA Primase; DNA Replication; Enzyme Induction; Flow Cytometry; HeLa Cells; Humans; Mice; Microscopy, Confocal; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; RNA Nucleotidyltransferases; RNA, Antisense; S Phase

1996
Increased sensitivity to oxidative injury in chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA.
    The Biochemical journal, 1996, Nov-01, Volume: 319 ( Pt 3)

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Benzamides; Cell Survival; CHO Cells; Cricetinae; DNA Methylation; DNA Primers; DNA, Complementary; Enzyme Inhibitors; Hydrogen Peroxide; Liver; Methionine Adenosyltransferase; NAD; Oxidants; Phenylenediamines; Polymerase Chain Reaction; Rats; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Transfection

1996
Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:11

    Topics: Animals; Benzamides; Brain; Brain Damage, Chronic; Brain Ischemia; Cerebral Infarction; DNA Damage; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Male; Mice; Mice, Inbred Strains; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases

1997
Peroxynitrate-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a nonseptic shock model induced by zymosan in the rat.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:5

    Topics: Animals; Benzamides; Disease Models, Animal; DNA Damage; Energy Metabolism; Enzyme Activation; Macrophages, Peritoneal; Male; Mitochondria; NAD; NG-Nitroarginine Methyl Ester; Niacinamide; Nitrates; Nitric Oxide Synthase; Oxidants; Oxygen Consumption; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Shock; Zymosan

1998
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres.
    Science (New York, N.Y.), 1998, Nov-20, Volume: 282, Issue:5393

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Ankyrins; Benzamides; Catalytic Domain; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Humans; Molecular Sequence Data; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Structure, Secondary; Recombinant Proteins; Repetitive Sequences, Amino Acid; Sequence Alignment; Sequence Homology, Amino Acid; Tankyrases; Telomere; Telomeric Repeat Binding Protein 1

1998
The involvement of poly(ADP-ribose) polymerase in the oxidative stress responses in plants.
    FEBS letters, 1998, Nov-27, Volume: 440, Issue:1-2

    Topics: Apoptosis; Arabidopsis; Benzamides; Blotting, Western; Calcium; Cells, Cultured; DNA Repair; Glycine max; Hydrogen Peroxide; In Situ Nick-End Labeling; Ionophores; NAD; Niacinamide; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; RNA, Antisense; Time Factors; Transformation, Genetic

1998
Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca2+ chelation: involvement of a common mechanism.
    Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1

    Topics: Adenosine Triphosphate; Benzamides; Caco-2 Cells; Calcium; Cell Death; Chelating Agents; DNA Damage; DNA, Neoplasm; Egtazic Acid; Glutathione; Humans; Hydrogen Peroxide; Kinetics; NAD; Naphthoquinones; Oxidants; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Vitamin K

1999
Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis.
    British journal of cancer, 1999, Volume: 80, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Caspases; Cell Survival; Colorectal Neoplasms; Dihydroxyacetone Phosphate; Doxorubicin; Fructosediphosphates; Glycerophosphates; Humans; Iodoacetates; Leukemia L1210; Magnetic Resonance Spectroscopy; Mechlorethamine; NAD; Niacinamide; Tumor Cells, Cultured

1999
Evidence for increased de novo synthesis of NAD in immune-activated RAW264.7 macrophages: a self-protective mechanism?
    Archives of biochemistry and biophysics, 1999, Dec-01, Volume: 372, Issue:1

    Topics: Animals; Benzamides; Cell Line; Dexamethasone; Enzyme Inhibitors; Interferon-gamma; Macrophage Activation; Macrophages; Mice; NAD; NG-Nitroarginine Methyl Ester; Niacinamide; Nitric Oxide Synthase; Poly(ADP-ribose) Polymerase Inhibitors; Quinolinic Acid; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase

1999
Effects of nicotinamide-related agents on the growth of primary rat hepatocytes and formation of small hepatocyte colonies.
    Liver, 1999, Volume: 19, Issue:6

    Topics: Albumins; Animals; Benzamides; Blotting, Northern; Bromodeoxyuridine; Cell Count; Cell Division; Cells, Cultured; Connexins; Enzyme Inhibitors; Gap Junction beta-1 Protein; Liver; Male; NAD; Niacin; Poly(ADP-ribose) Polymerase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tryptophan Oxygenase

1999
Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: Animals; Benzamides; Blotting, Northern; Blotting, Western; Cell Death; Cell Survival; Disease Models, Animal; DNA Repair; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hippocampus; Immunohistochemistry; In Situ Hybridization; Ischemic Attack, Transient; Male; NAD; Neurons; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stroke

2000
A scintillation proximity assay for poly(ADP-ribose) polymerase.
    Analytical biochemistry, 2000, Jun-15, Volume: 282, Issue:1

    Topics: Animals; Autoradiography; Benzamides; Biotinylation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunoblotting; Inhibitory Concentration 50; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Scintillation Counting; Time Factors

2000
IDO induction in IFN-gamma activated astroglia: a role in improving cell viability during oxidative stress.
    Redox report : communications in free radical research, 2000, Volume: 5, Issue:2-3

    Topics: Astrocytes; Astrocytoma; Benzamides; Cell Survival; Enzyme Induction; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; NAD; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured

2000
Depletion of intracellular NAD(+) and ATP levels during ricin-induced apoptosis through the specific ribosomal inactivation results in the cytolysis of U937 cells.
    Journal of biochemistry, 2000, Volume: 128, Issue:3

    Topics: Adenosine Triphosphate; Apoptosis; Benzamides; Blotting, Western; Cells, Cultured; Diphtheria Toxin; Humans; Microscopy, Fluorescence; NAD; Plant Proteins; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Ribosomes; Ricin; Time Factors; U937 Cells

2000
Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Sep-15, Volume: 20, Issue:18

    Topics: Animals; Apoptosis; Benzamides; Calcium; Cells, Cultured; DNA; DNA Damage; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Homocysteine; Intracellular Fluid; Kainic Acid; Membrane Potentials; Mitochondria; NAD; Neurons; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Tumor Suppressor Protein p53

2000
Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase.
    Molecular medicine (Cambridge, Mass.), 2001, Volume: 7, Issue:6

    Topics: Animals; Benzamides; Enzyme Inhibitors; Immunohistochemistry; Interleukin-10; Interleukin-12; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Knockout; Myocardial Reperfusion Injury; Myocardium; NAD; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Tissue Extracts; Tumor Necrosis Factor-alpha; Tyrosine

2001
Different effects of tert-butylhydroperoxide-induced peroxynitrite-dependent and -independent DNA single-strand breakage on PC12 cell poly(ADP-ribose) polymerase activity.
    European journal of biochemistry, 2001, Volume: 268, Issue:20

    Topics: Animals; Benzamides; Cattle; CHO Cells; Cricetinae; DNA Damage; DNA Repair; DNA, Single-Stranded; Enzyme Activation; Humans; NAD; NG-Nitroarginine Methyl Ester; PC12 Cells; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Rats; tert-Butylhydroperoxide; Time Factors; U937 Cells

2001
The inhibition of poly(ADP-ribose) polymerase enhances growth rates of ataxia telangiectasia cells.
    Archives of biochemistry and biophysics, 2002, Jun-15, Volume: 402, Issue:2

    Topics: Adenosine Triphosphate; Ataxia Telangiectasia; Benzamides; Blotting, Western; Cell Division; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Humans; Isoquinolines; NAD; Poly(ADP-ribose) Polymerase Inhibitors

2002
Poly(ADP-ribose) polymerase inhibition prevents both apoptotic-like delayed neuronal death and necrosis after H(2)O(2) injury.
    Journal of neurochemistry, 2002, Volume: 82, Issue:1

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzamides; Caspase 3; Caspases; Cell Death; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; NAD; NADP; Necrosis; Neurons; Neuroprotective Agents; PC12 Cells; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats

2002
Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes.
    Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:8

    Topics: Animals; Apoptosis; Benzamides; Caspase 3; Caspases; Cytochrome c Group; Mitochondria; Myocytes, Cardiac; NAD; Necrosis; Nitric Oxide; Oligopeptides; Rats; Rats, Sprague-Dawley; Triazenes

2002
Beneficial effects of poly (ADP-ribose) polymerase inhibition against the reperfusion injury in heart transplantation.
    Free radical research, 2003, Volume: 37, Issue:3

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzamides; Blotting, Western; Caspase 3; Caspases; Cell Nucleus; Creatine Kinase; DNA Damage; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Heart Transplantation; L-Lactate Dehydrogenase; Lipid Peroxidation; Myocardium; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Reperfusion Injury; Temperature; Troponin I

2003
Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time.
    Nucleic acids research, 2003, Sep-01, Volume: 31, Issue:17

    Topics: Animals; Benzamides; CHO Cells; Comet Assay; Cricetinae; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Single-Stranded; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genotype; Isoquinolines; Methyl Methanesulfonate; Mutation; NAD; NADP; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Time Factors; X-ray Repair Cross Complementing Protein 1

2003
Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.
    European journal of medical research, 2003, Oct-22, Volume: 8, Issue:10

    Topics: 1-Naphthylamine; Adenosine Triphosphate; Alkylating Agents; Apoptosis; Benzamides; Cell Death; Cell Line, Tumor; Cell Size; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia; Melphalan; Methylnitronitrosoguanidine; NAD; Naphthalimides; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones

2003
Prevention of myocardial reperfusion injury by poly(ADP-ribose) synthetase inhibitor, 3-aminobenzamide, in cardioplegic solution: in vitro study of isolated rat heart model.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2004, Volume: 26, Issue:2

    Topics: Animals; Apoptosis; Benzamides; Cardiac Surgical Procedures; Cardioplegic Solutions; Disease Models, Animal; DNA; Enzyme Inhibitors; Heart; Heart Arrest, Induced; Male; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Myocardium; NAD; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Time Factors; Ventricular Function, Left

2004
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.
    Science (New York, N.Y.), 2004, Aug-13, Volume: 305, Issue:5686

    Topics: 3T3 Cells; Animals; Axons; Axotomy; Benzamides; Cell Line; Cell Nucleus; Cell Survival; Cells, Cultured; Ganglia, Spinal; Humans; Lentivirus; Mice; Mutation; NAD; Naphthols; Nerve Tissue Proteins; Neuroprotective Agents; Nicotinamide-Nucleotide Adenylyltransferase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Resveratrol; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stilbenes; Ubiquitin-Protein Ligases; Vincristine; Wallerian Degeneration

2004
MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.
    Diabetes, 2006, Volume: 55, Issue:3

    Topics: Antioxidants; Benzamides; Cells, Cultured; Enzyme Inhibitors; Homeodomain Proteins; Insulin; Insulin-Secreting Cells; Isoquinolines; Maf Transcription Factors, Large; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Promoter Regions, Genetic; RNA, Messenger; Trans-Activators

2006
The involvement of ATP produced via (ADP-Ribose)n in the maintenance of DNA replication apparatus during DNA repair.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3

    Topics: Adenosine Triphosphate; Benzamides; Cell Nucleus; Chromatography, High Pressure Liquid; Chromosomal Proteins, Non-Histone; Diphosphates; DNA Damage; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoside Hydrolases; HeLa Cells; Humans; Hydrolyzable Tannins; Methylnitronitrosoguanidine; Models, Biological; NAD; Poly Adenosine Diphosphate Ribose; S Phase; Thymidine Monophosphate

2007
Xanthomonas caspase displays an inherent PARP-like activity.
    FEMS microbiology letters, 2007, Volume: 272, Issue:2

    Topics: Amidohydrolases; Amino Acid Sequence; Bacterial Proteins; Benzamides; Blotting, Western; Caspases; Cell Death; Cloning, Molecular; Cross Reactions; Culture Media; Enzyme Inhibitors; Immunoprecipitation; Molecular Sequence Data; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Structure, Tertiary; Sequence Alignment; Xanthomonas campestris

2007
Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression.
    European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3

    Topics: Alcohol Oxidoreductases; Antioxidants; Benzamides; Cell Line, Tumor; Cell Nucleus; Cyclic N-Oxides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferrous Compounds; Flavones; Flavonoids; Gene Expression Regulation; Humans; Hydrogen Peroxide; Interleukin-8; Lipopolysaccharides; Methylnitronitrosoguanidine; Molecular Structure; NAD; NF-kappa B; Nucleotidases; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; Spin Trapping; Transcription, Genetic

2007
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
    Toxicology letters, 2007, Volume: 172, Issue:3

    Topics: Benzamides; Benzoflavones; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Survival; Coumarins; DNA Breaks; Environmental Pollutants; Estrogen Receptor alpha; Glutathione; Humans; NAD; NADP; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Tamoxifen

2007
Local administration of the poly(ADP-ribose) polymerase inhibitor INO-1001 prevents NAD+ depletion and improves water maze performance after traumatic brain injury in mice.
    Journal of neurotrauma, 2007, Volume: 24, Issue:8

    Topics: Animals; Brain Injuries; Indoles; Injections, Intralesional; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; NAD; Poly(ADP-ribose) Polymerase Inhibitors

2007
Continuous inhibition of poly(ADP-ribose) polymerase does not reduce reperfusion injury in isolated rat heart.
    Journal of cardiovascular pharmacology, 2013, Volume: 62, Issue:1

    Topics: Animals; Apoptosis; Benzamides; Blotting, Western; Cardiotonic Agents; Enzyme Inhibitors; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NAD; Oncogene Protein v-akt; Phosphocreatine; Phosphorus; Phosphorylation; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Sodium; Sodium Radioisotopes; Treatment Failure; Ventricular Function, Left

2013
Poly (ADP-ribose) polymerase-1 inhibitor, 3-aminobenzamide pretreatment ameliorates lipopolysaccharide-induced neurobehavioral and neurochemical anomalies in mice.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 133

    Topics: Animals; Benzamides; Catalase; Glutathione; Hippocampus; Imipramine; Immobility Response, Tonic; Interleukin-1beta; Lipid Peroxidation; Lipopolysaccharides; Male; Mice; Motor Activity; NAD; Nitrites; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2015
PARP inhibition attenuates neuroinflammation and oxidative stress in chronic constriction injury induced peripheral neuropathy.
    Life sciences, 2016, Apr-01, Volume: 150

    Topics: Animals; Benzamides; Constriction, Pathologic; Cyclooxygenase 2; Hyperalgesia; Inflammation; Male; NAD; Neuritis; Neuroprotective Agents; Oxidative Stress; Pain Measurement; Peripheral Nervous System Diseases; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Sensation; Tyrosine; Walking

2016