nad has been researched along with 1-methyl-4-phenylpyridinium in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 10 (38.46) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arora, PK; Harik, SI; Hoppel, CL; Riachi, NJ; Sayre, LM; Wang, FJ | 1 |
| Hasegawa, E; Minakami, S; Murai, Y; Oishi, T; Takeshige, K | 1 |
| Albores, R; Collins, MA; Drucker, G; Fields, JZ; Neafsey, EJ | 1 |
| Heikkila, RE; Jin, YZ; McKeown, KA; Nicklas, WJ; Ramsay, RR; Singer, TP; Youngster, SK | 1 |
| Ramsay, RR; Salach, JI; Singer, TP | 1 |
| Booth, RG; Johnson, EA; McKeown, KA; Ramsay, RR; Singer, TP | 1 |
| Frei, B; Richter, C | 1 |
| Hassan, MN; Thakar, JH | 1 |
| Heikkila, RE; Nicklas, WJ; Vyas, I | 1 |
| Dadgar, J; Ramsay, RR; Singer, TP; Trevor, A | 1 |
| Mizuno, Y; Saitoh, T; Sone, N | 1 |
| Castagnoli, N; Ramsay, RR; Singer, TP; Trevor, AJ | 1 |
| Krueger, MJ; Murphy, MP; Ramsay, RR; Sablin, SO; Singer, TP | 1 |
| Adams, JD; Cadenas, E; Kim, SS; Klaidman, LK; Leung, AC | 1 |
| Ackrell, BA; Krueger, MJ; Singer, TP; Tan, AK | 1 |
| Greenamyre, JT; Higgins, DS | 1 |
| Bennett, JP; Davis, RE; Miller, SW; Parker, WD; Parks, JK; Sheehan, JP; Swerdlow, RH; Trimmer, PA; Tuttle, JB | 1 |
| Inoue, M; Iwamura, H; Miyoshi, H; Ohshima, M; Okamoto, S; Sakamoto, K | 1 |
| Cosi, C; Marien, M | 1 |
| Burkhardt, K; Kaftan, A; Schwarz, J; Storch, A | 1 |
| Casida, JE; Schuler, F | 1 |
| Baudry, M; Fonck, C | 1 |
| Alonso, JC; Fuentes, JM; González-Polo, RA; Rodríguez-Martín, A; Soler, G | 1 |
| Choi, WS; Palmiter, RD; Xia, Z | 1 |
| Antenor-Dorsey, JA; O'Malley, KL | 1 |
| Chakraborty, S; Chiou, A; Karmenyan, A; Tsai, JW | 1 |
26 other study(ies) available for nad and 1-methyl-4-phenylpyridinium
| Article | Year |
|---|---|
Dopaminergic neurotoxicity in vivo and inhibition of mitochondrial respiration in vitro by possible endogenous pyridinium-like substances.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Anions; Dopamine; Mitochondria; NAD; Neurotoxins; Oxidation-Reduction; Oxygen Consumption; Pyridinium Compounds; Quinolinium Compounds; Rats; Succinates; Succinic Acid; Tetraphenylborate | 1991 |
1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cattle; Free Radicals; Lipid Peroxidation; Mitochondria, Heart; NAD; Submitochondrial Particles; Superoxides | 1990 |
Mitochondrial respiratory inhibition by N-methylated beta-carboline derivatives structurally resembling N-methyl-4-phenylpyridine.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Carbolines; Female; Harmine; Kinetics; Mitochondria, Liver; NAD; Oxygen Consumption; Polarography; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |
Structural dependence of the inhibition of mitochondrial respiration and of NADH oxidase by 1-methyl-4-phenylpyridinium (MPP+) analogs and their energized accumulation by mitochondria.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Kinetics; Mitochondria, Liver; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Oxygen Consumption; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1989 |
Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport, Active; Electron Transport; Glutamates; Glutamic Acid; Intracellular Membranes; Malates; Mitochondria, Heart; Mitochondria, Liver; NAD; NAD(P)H Dehydrogenase (Quinone); Pyridinium Compounds; Quinone Reductases; Rats; Succinates; Succinic Acid | 1986 |
Inhibition of NADH oxidation by pyridine derivatives.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Cytochrome Reductases; Glutamates; Glutamic Acid; Intracellular Membranes; Mitochondria, Heart; Mitochondria, Liver; NAD; NADH Dehydrogenase; Oxidation-Reduction; Oxygen Consumption; Pyridines; Pyridinium Compounds; Rats; Structure-Activity Relationship | 1987 |
N-methyl-4-phenylpyridine (MMP+) together with 6-hydroxydopamine or dopamine stimulates Ca2+ release from mitochondria.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dopamine; Egtazic Acid; Female; Hydroxydopamines; In Vitro Techniques; Mitochondria; NAD; Oxidopamine; Parkinson Disease, Secondary; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains | 1986 |
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), cyperquat (MPP+) and paraquat on isolated mitochondria from rat striatum, cortex and liver.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Animals; Cerebral Cortex; Corpus Striatum; Flavin-Adenine Dinucleotide; Malates; Mitochondria; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Paraquat; Phosphorylation; Pyridines; Pyridinium Compounds; Pyruvates; Pyruvic Acid; Rats; Succinates; Succinic Acid | 1988 |
Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Amino Acids; Animals; Brain; Corpus Striatum; Malates; Male; Mice; Mitochondria; NAD; Oxidation-Reduction; Oxygen Consumption; Pyridines; Pyridinium Compounds; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Energy Metabolism; Male; Mitochondria; NAD; Oxygen Consumption; Potassium; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Temperature; Valinomycin | 1986 |
Inhibition of mitochondrial alpha-ketoglutarate dehydrogenase by 1-methyl-4-phenylpyridinium ion.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Brain; Citric Acid Cycle; In Vitro Techniques; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Male; Mice; Mice, Inbred C57BL; Mitochondria; NAD; NADP; Oxygen Consumption; Pyridinium Compounds | 1987 |
Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Biotransformation; Brain; Humans; Mitochondria; Monoamine Oxidase; NAD; Parkinson Disease, Secondary; Pyridines; Pyridinium Compounds; Rats | 1987 |
Inhibition of complex I by hydrophobic analogues of N-methyl-4-phenylpyridinium (MPP+) and the use of an ion-selective electrode to measure their accumulation by mitochondria and electron-transport particles.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cations; Cattle; Electron Transport; Female; Intracellular Membranes; Ion-Selective Electrodes; Mitochondria, Heart; Mitochondria, Liver; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Pyridinium Compounds; Rats; Rats, Wistar | 1995 |
Redox cycling of MPP+: evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Aldehyde Dehydrogenase; Dihydrolipoamide Dehydrogenase; Electron Spin Resonance Spectroscopy; Hydroxides; Hydroxyl Radical; NAD; Oxidation-Reduction; Photolysis; Superoxides; Ultraviolet Rays; Xanthine Oxidase | 1993 |
Is complex II involved in the inhibition of mitochondrial respiration by N-methyl-4-phenylpyridinium cation (MMP+) and N-methyl-beta-carbolines?
Topics: 1-Methyl-4-phenylpyridinium; Animals; Carbolines; Cations; Cattle; Methylation; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; NAD; Oxygen Consumption; Rats; Submitochondrial Particles; Succinate Dehydrogenase; Succinates; Succinic Acid | 1993 |
[3H]dihydrorotenone binding to NADH: ubiquinone reductase (complex I) of the electron transport chain: an autoradiographic study.
Topics: 1-Methyl-4-phenylpyridinium; Adenine Nucleotides; Animals; Autoradiography; Brain; Electron Transport; Entorhinal Cortex; Insecticides; Male; Mitochondria; N-Methylaspartate; NAD; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Rotenone; Sensitivity and Specificity; Tritium | 1996 |
Origin and functional consequences of the complex I defect in Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Aged; Apoptosis; Cell Death; DNA, Mitochondrial; Female; Humans; Male; Middle Aged; Muscle, Skeletal; NAD; NAD(P)H Dehydrogenase (Quinone); Parkinson Disease; Point Mutation | 1996 |
Probing the ubiquinone reduction site of mitochondrial complex I using novel cationic inhibitors.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Binding Sites; Cattle; Electron Transport Complex I; NAD; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Proton Pumps; Tetraphenylborate; Ubiquinone | 1997 |
Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP): prevention by the poly(ADP-ribose) polymerase inhibitor, benzamide.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzamides; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Frontal Lobe; Male; Mesencephalon; Mice; Mice, Inbred C57BL; NAD; Neuroprotective Agents; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Pyridinium Compounds | 1998 |
1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (salsolinol) is toxic to dopaminergic neuroblastoma SH-SY5Y cells via impairment of cellular energy metabolism.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Dopamine; Dose-Response Relationship, Drug; Electron Transport Complex I; Electron Transport Complex II; Energy Metabolism; Glucose; Herbicides; Humans; Isoquinolines; Mitochondria; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Neuroblastoma; Oxidoreductases; Parkinson Disease, Secondary; Rotenone; Succinate Dehydrogenase; Tumor Cells, Cultured; Uncoupling Agents | 2000 |
Functional coupling of PSST and ND1 subunits in NADH:ubiquinone oxidoreductase established by photoaffinity labeling.
Topics: 1-Methyl-4-phenylpyridinium; Binding Sites; Electron Transport Complex I; Enzyme Inhibitors; Enzyme Stability; Hot Temperature; Molecular Structure; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Photoaffinity Labels; Polyenes; Pyridazines; Rotenone; Structure-Activity Relationship; Tritium; Ubiquinone | 2001 |
Toxic effects of MPP(+) and MPTP in PC12 cells independent of reactive oxygen species formation.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Cell Differentiation; Cell Survival; Dopamine; Dopamine Agents; Drug Interactions; Free Radical Scavengers; Herbicides; Lipid Peroxidation; NAD; Nerve Growth Factor; Neurons; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Rats; Reactive Oxygen Species; Substantia Nigra; Tritium | 2001 |
MPP(+) causes inhibition of cellular energy supply in cerebellar granule cells.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Dopamine Agents; Dose-Response Relationship, Drug; Energy Metabolism; Female; Glucose; Glycolysis; Lactic Acid; Male; Mitochondria; NAD; Neurons; Nucleotides; Rats; Rats, Wistar | 2003 |
Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cytoplasm; Disease Models, Animal; Dopamine; Electron Transport Complex I; Mice; Microtubules; NAD; Nerve Degeneration; Parkinson Disease; Reactive Oxygen Species; Rotenone; Substantia Nigra; Vesicular Monoamine Transport Proteins | 2011 |
WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Axons; Cells, Cultured; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutation; NAD; Nerve Tissue Proteins; Neurites; Neuroprotective Agents; Nicotinamide-Nucleotide Adenylyltransferase; Parkinson Disease; Wallerian Degeneration | 2012 |
Inhibitory effects of curcumin and cyclocurcumin in 1-methyl-4-phenylpyridinium (MPP
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Differentiation; Cell Survival; Curcumin; Microscopy, Fluorescence; NAD; Nerve Growth Factor; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; PC12 Cells; Rats; Reactive Oxygen Species | 2017 |