nad has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (42.11) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heikkila, RE; Nicklas, WJ; Ofori, S | 1 |
| Heikkila, RE; Nicklas, WJ; Vyas, I | 2 |
| Frei, B; Richter, C | 1 |
| Hassan, MN; Thakar, JH | 1 |
| Dadgar, J; Ramsay, RR; Singer, TP; Trevor, A | 1 |
| Castagnoli, N; Ramsay, RR; Singer, TP; Trevor, AJ | 1 |
| Abell, CW; Brossi, A; Gessner, W; Shen, RS | 1 |
| Holdup, D; Liptrot, J; Phillipson, O | 1 |
| Adams, JD; Cadenas, E; Kim, SS; Klaidman, LK; Leung, AC | 1 |
| Adams, JD; Klaidman, LK; Mukherjee, SK; Yasharel, R | 1 |
| Cosi, C; Marien, M | 2 |
| Baudry, M; Fonck, C | 1 |
| Caspersen, C; Jackson-Lewis, V; Naini, A; Perier, C; Przedborski, S; Ramasamy, R; Teismann, P; Tieu, K; Vila, M; Wu, DC; Yan, SD | 1 |
| Joshi, SD; Karunakaran, S; Koumar, RC; Meka, DP; Nidadavolu, P; Ramakrishnan, S; Ravindranath, V; Saeed, U | 1 |
| Acuña-Castroviejo, D; Camacho, E; Carrión, MD; Doerrier, C; Escames, G; Espinosa, A; López, LC; Mora, F; Tapias, V | 1 |
| Cai, AL; Sheline, CT; Shi, C; Zhang, W; Zhu, J | 1 |
| Abd Alrahman Alobaidy, A; Al-Adawi, S; Al-Asmi, A; Al-Senawi, H; Braidy, N; Essa, MM; Guillemin, GJ; Lakhtakia, R; Selvaraju, S; Vaishnav, R | 1 |
19 other study(ies) available for nad and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
| Article | Year |
|---|---|
Attenuation by dopamine uptake blockers of the inhibitory effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and some of its analogs on NADH-linked metabolism in mouse neostriatal slices.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cocaine; Corpus Striatum; Dopamine; In Vitro Techniques; Lactates; Lactic Acid; Male; Mice; NAD; Neurotransmitter Uptake Inhibitors; Rats; Tyrosine 3-Monooxygenase | 1989 |
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Diphosphate; Animals; Brain; Glutamates; Glutamic Acid; Malates; Male; Mice; Mitochondria; NAD; Neurotoxins; Oxidation-Reduction; Phosphorylation; Pyridines; Rats; Rats, Inbred Strains | 1985 |
N-methyl-4-phenylpyridine (MMP+) together with 6-hydroxydopamine or dopamine stimulates Ca2+ release from mitochondria.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dopamine; Egtazic Acid; Female; Hydroxydopamines; In Vitro Techniques; Mitochondria; NAD; Oxidopamine; Parkinson Disease, Secondary; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains | 1986 |
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), cyperquat (MPP+) and paraquat on isolated mitochondria from rat striatum, cortex and liver.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Animals; Cerebral Cortex; Corpus Striatum; Flavin-Adenine Dinucleotide; Malates; Mitochondria; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Paraquat; Phosphorylation; Pyridines; Pyridinium Compounds; Pyruvates; Pyruvic Acid; Rats; Succinates; Succinic Acid | 1988 |
Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Amino Acids; Animals; Brain; Corpus Striatum; Malates; Male; Mice; Mitochondria; NAD; Oxidation-Reduction; Oxygen Consumption; Pyridines; Pyridinium Compounds; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Energy Metabolism; Male; Mitochondria; NAD; Oxygen Consumption; Potassium; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Temperature; Valinomycin | 1986 |
Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Biotransformation; Brain; Humans; Mitochondria; Monoamine Oxidase; NAD; Parkinson Disease, Secondary; Pyridines; Pyridinium Compounds; Rats | 1987 |
Inhibition of dihydropteridine reductase by novel 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydropteridine Reductase; Humans; Hydroxylation; Liver; NAD; NADH, NADPH Oxidoreductases; Pyridines; Rats; Structure-Activity Relationship; Synaptosomes | 1984 |
1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol inhibits tyrosine hydroxylase activity in rat striatal synaptosomes.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biopterins; Chromatography, High Pressure Liquid; Clorgyline; Corpus Striatum; Dopamine; Isoquinolines; Monoamine Oxidase; NAD; Nerve Tissue Proteins; Nomifensine; Parkinson Disease; Rats; Selegiline; Sulpiride; Synaptosomes; Tyrosine 3-Monooxygenase | 1994 |
Redox cycling of MPP+: evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Aldehyde Dehydrogenase; Dihydrolipoamide Dehydrogenase; Electron Spin Resonance Spectroscopy; Hydroxides; Hydroxyl Radical; NAD; Oxidation-Reduction; Photolysis; Superoxides; Ultraviolet Rays; Xanthine Oxidase | 1993 |
Increased brain NAD prevents neuronal apoptosis in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Brain; DNA Fragmentation; Electron Spin Resonance Spectroscopy; Free Radicals; Immunohistochemistry; Mice; Mice, Inbred C57BL; NAD; Neurons; Niacinamide; Substantia Nigra | 1997 |
Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP): prevention by the poly(ADP-ribose) polymerase inhibitor, benzamide.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzamides; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Frontal Lobe; Male; Mesencephalon; Mice; Mice, Inbred C57BL; NAD; Neuroprotective Agents; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Pyridinium Compounds | 1998 |
Implication of poly (ADP-ribose) polymerase (PARP) in neurodegeneration and brain energy metabolism. Decreases in mouse brain NAD+ and ATP caused by MPTP are prevented by the PARP inhibitor benzamide.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Benzamides; Brain; Corpus Striatum; Dopamine; Dopamine Agents; Frontal Lobe; Male; Mesencephalon; Mice; Mice, Inbred C57BL; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 1999 |
Toxic effects of MPP(+) and MPTP in PC12 cells independent of reactive oxygen species formation.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Cell Differentiation; Cell Survival; Dopamine; Dopamine Agents; Drug Interactions; Free Radical Scavengers; Herbicides; Lipid Peroxidation; NAD; Nerve Growth Factor; Neurons; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Rats; Reactive Oxygen Species; Substantia Nigra; Tritium | 2001 |
D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Brain; Cell Respiration; Dopamine; Dopamine Agents; Electron Transport; Electron Transport Complex I; Humans; Hydrogen Peroxide; Hydroxybutyrate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mitochondria; Motor Activity; NAD; NADH, NADPH Oxidoreductases; Neurons; Neuroprotective Agents; Oxidants; Oxygen; Parkinson Disease; Tyrosine 3-Monooxygenase | 2003 |
Redox activated MAP kinase death signaling cascade initiated by ASK1 is not activated in female mice following MPTP: novel mechanism of neuroprotection.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Carrier Proteins; Co-Repressor Proteins; Dopamine; Female; Gene Expression Regulation; Glutathione Reductase; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Kinase Kinase 5; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Models, Biological; Molecular Chaperones; NAD; Neurons; Neurotoxins; Nuclear Proteins; Oncogene Proteins; Oxidation-Reduction; Peroxiredoxins; Protein Deglycase DJ-1; Protein Transport; Sex Factors; Thioredoxin-Disulfide Reductase; Time Factors | 2009 |
Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Cytosol; Disease Models, Animal; Drug Administration Schedule; Kynurenine; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mitochondria; MPTP Poisoning; NAD; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Substantia Nigra | 2011 |
Mitochondrial inhibitor models of Huntington's disease and Parkinson's disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carrier Proteins; Cation Transport Proteins; Cell Death; Cells, Cultured; Cerebral Cortex; Dihydroxyacetone Phosphate; Disease Models, Animal; Drug Interactions; Embryo, Mammalian; Fructose-Bisphosphatase; Humans; Huntington Disease; Male; Matrix Metalloproteinase 16; Membrane Proteins; Membrane Transport Proteins; Mental Disorders; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; NAD; Neurons; Niacinamide; Nitro Compounds; Oxidopamine; Parkinson Disease; Propionates; Pyruvic Acid; Rats; Rats, Long-Evans; Tyrosine 3-Monooxygenase; Zinc | 2013 |
Neuroprotective effects of a variety of pomegranate juice extracts against MPTP-induced cytotoxicity and oxidative stress in human primary neurons.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Antioxidants; Beverages; Cell Death; Cell Survival; Cells, Cultured; Humans; Lipid Peroxidation; Lythraceae; NAD; Neurons; Neuroprotective Agents; Neurotoxins; Oman; Oxidative Stress; Phenols; Plant Extracts; Reactive Oxygen Species | 2013 |