Page last updated: 2024-09-03

naadp and thapsigargin

naadp has been researched along with thapsigargin in 23 studies

Compound Research Comparison

Studies (naadp)	Trials (naadp)	Recent Studies (post-2010) (naadp)	Studies (thapsigargin)	Trials (thapsigargin)	Recent Studies (post-2010) (thapsigargin)
411	0	184	5,234	3	918

Protein Interaction Comparison

Protein	Taxonomy	naadp (IC50)	thapsigargin (IC50)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Oryctolagus cuniculus (rabbit)		0.002

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (13.04)	18.2507
2000's	16 (69.57)	29.6817
2010's	4 (17.39)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Galione, A; Genazzani, AA	1
Chini, EN; Dousa, TP	1
Dubé, F; Eckberg, WR; Galione, A; Thomas, TW	1
Gylfe, E; Hellman, B; Tengholm, A	1
Churchill, GC; Galione, A	1
Li, X; Mohanty, MJ; Rossi, NF; Ye, M	1
Brailoiu, E; Dun, NJ; Miyamoto, MD	1
Johnson, JD; Misler, S	1
Brailoiu, E; Dun, NJ; Patel, S	1
Dolman, NJ; Gerasimenko, JV; Gerasimenko, OV; Maruyama, Y; Petersen, OH; Tepikin, AV; Yano, K	1
Ashcroft, SJ; Churchill, GC; Galione, A; Masgrau, R; Morgan, AJ; Patel, S; Yamasaki, M	1
Gerasimenko, J; Gerasimenko, O	1
Brailoiu, E; Brailoiu, GC; Dun, NJ; Dun, SL; Filipeanu, CM; Hoard, JL; Patel, S	1
López, JJ; Pariente, JA; Redondo, PC; Rosado, JA; Salido, GM	1
Bak, J; Mándi, M; Timár, G; Tóth, B	1
Gerasimenko, JV; Gerasimenko, OV; Petersen, OH; Sherwood, M; Tepikin, AV	1
Churchill, GC; Galione, A; Macgregor, A; Parkesh, R; Rakovic, S; Sanders, L; Terrar, DA; Yamasaki, M	1
Guse, AH; Kirchberger, T; Steen, M	1
Biel, M; Cuny, H; Fenske, S; Griesbeck, O; Gruner, C; Harz, H; Rötzer, K; Schieder, M; Wahl-Schott, C; Zong, X	1
Harper, AG; Mason, MJ; Pugh, N; Sage, SO	1
Lee, AK; Tse, A; Yeung-Yam-Wah, V	1
Agbani, E; Evans, AM; Li, J; Ma, J; Ogunbayo, OA; Shen, B; Zhu, MX; Zhu, Y	1
Denti, F; Gagliano, G; Genazzani, AA; Guerra, G; Lim, D; Mapelli, L; Moccia, F; Pinton, P; Potenza, DM; Ronco, V; Tognolina, M; Vullo, S	1

Reviews

1 review(s) available for naadp and thapsigargin

Article	Year
New aspects of nuclear calcium signalling. Journal of cell science, 2004, Jul-01, Volume: 117, Issue:Pt 15 Topics: Animals; Calcium; Cell Nucleus; Cyclic ADP-Ribose; Endoplasmic Reticulum; Humans; Inositol 1,4,5-Trisphosphate; Lysosomes; Models, Biological; NADP; Pancreas; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Thapsigargin	2004

Other Studies

22 other study(ies) available for naadp and thapsigargin

Article	Year
Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive pool. The Biochemical journal, 1996, May-01, Volume: 315 ( Pt 3) Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Cyclic ADP-Ribose; Drug Resistance; Enzyme Inhibitors; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ion Transport; NADP; Organelles; Ovum; Sea Urchins; Terpenes; Thapsigargin	1996
Nicotinate-adenine dinucleotide phosphate-induced Ca(2+)-release does not behave as a Ca(2+)-induced Ca(2+)-release system. The Biochemical journal, 1996, Jun-15, Volume: 316 ( Pt 3) Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cyclic ADP-Ribose; Egtazic Acid; Enzyme Inhibitors; Female; Gallic Acid; Kinetics; NADP; Ovum; Sea Urchins; Terpenes; Thapsigargin	1996
Mechanisms of calcium release and sequestration in eggs of Chaetopterus pergamentaceus. Cell calcium, 1998, Volume: 24, Issue:4 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Extracts; Cyclic ADP-Ribose; Female; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Male; NADP; Ovum; Polychaeta; Receptors, Cytoplasmic and Nuclear; Ryanodine; Spermatozoa; Thapsigargin; Thimerosal	1998
Mobilization of Ca2+ stores in individual pancreatic beta-cells permeabilized or not with digitonin or alpha-toxin. Cell calcium, 2000, Volume: 27, Issue:1 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Bacterial Toxins; Caffeine; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Compartmentation; Cell Membrane Permeability; Cyclic ADP-Ribose; Cytoplasm; Digitonin; Enzyme Inhibitors; Hemolysin Proteins; Inositol 1,4,5-Trisphosphate; Ionophores; Islets of Langerhans; Mice; Mice, Obese; NADP; Organelles; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin	2000
NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ stores. The EMBO journal, 2001, Jun-01, Volume: 20, Issue:11 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Calcium Signaling; Cyclic ADP-Ribose; Female; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Models, Biological; NADP; Oocytes; Oscillometry; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Thapsigargin	2001
Hypotonic swelling-induced Ca(2+) release by an IP(3)-insensitive Ca(2+) store. American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:2 Topics: Animals; Calcium; Cell Line; Enzyme Inhibitors; Hypotonic Solutions; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Muscle, Smooth, Vascular; NADP; Osmolar Concentration; Ryanodine; Thapsigargin	2001
Nicotinic acid adenine dinucleotide phosphate enhances quantal neurosecretion at the frog neuromuscular junction: possible action on synaptic vesicles in the releasable pool. Molecular pharmacology, 2001, Volume: 60, Issue:4 Topics: Adenosine Diphosphate Ribose; Animals; Calcimycin; Cyclic ADP-Ribose; Drug Interactions; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; NADP; Neuromuscular Junction; Neurosecretion; Rana pipiens; Synaptic Vesicles; Thapsigargin	2001
Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells. Proceedings of the National Academy of Sciences of the United States of America, 2002, Oct-29, Volume: 99, Issue:22 Topics: Caffeine; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Cells, Cultured; Electrophysiology; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate Receptors; Insulin; Intracellular Fluid; Islets of Langerhans; Macrocyclic Compounds; NADP; Oxazoles; Receptors, Cytoplasmic and Nuclear; Thapsigargin	2002
Modulation of spontaneous transmitter release from the frog neuromuscular junction by interacting intracellular Ca(2+) stores: critical role for nicotinic acid-adenine dinucleotide phosphate (NAADP). The Biochemical journal, 2003, Jul-15, Volume: 373, Issue:Pt 2 Topics: Animals; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Electrophysiology; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Muscles; NADP; Neuromuscular Junction; Neurotransmitter Agents; Phosphorylcholine; Rana pipiens; Sphingosine; Thapsigargin; Wound Healing	2003
NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors. The Journal of cell biology, 2003, Oct-27, Volume: 163, Issue:2 Topics: Animals; Calcium; Cyclic ADP-Ribose; Fluorescent Dyes; Inositol 1,4,5-Trisphosphate; Mice; Mice, Inbred Strains; Models, Biological; NADP; Nuclear Envelope; Pancreas; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin	2003
Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells. The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8 Topics: Acetylcholine; Animals; Bombesin; Calcium; Cell Line; Endoplasmic Reticulum; Enzyme Inhibitors; Islets of Langerhans; Lysosomes; Macrolides; Male; Mice; Models, Biological; NADP; Organelles; Pancreas; Signal Transduction; Thapsigargin; Time Factors; Ultraviolet Rays	2004
Nicotinic acid adenine dinucleotide phosphate potentiates neurite outgrowth. The Journal of biological chemistry, 2005, Feb-18, Volume: 280, Issue:7 Topics: Animals; Calcium; Cell Enlargement; Cell Shape; Cells, Cultured; Inositol Phosphates; Liposomes; Macrocyclic Compounds; Macrolides; NADP; Neurites; Oxazoles; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin	2005
Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets. Cellular signalling, 2006, Volume: 18, Issue:3 Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Compartmentation; Estrenes; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Isoenzymes; NADP; Nimodipine; Pyrrolidinones; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Thrombin; Type C Phospholipases; Vasopressins	2006
Ca2+ release triggered by NAADP in hepatocyte microsomes. The Biochemical journal, 2006, Apr-15, Volume: 395, Issue:2 Topics: Animals; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Hepatocytes; Hydrogen-Ion Concentration; Liver; Macrolides; Microsomes, Liver; NADP; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Thapsigargin; Time Factors	2006
NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area. Journal of cell science, 2006, Jan-15, Volume: 119, Issue:Pt 2 Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Cyclic ADP-Ribose; Endoplasmic Reticulum; Enzyme Inhibitors; Fluorescent Dyes; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Ionophores; Macrolides; Mice; NADP; Nigericin; Pancreas; Secretory Vesicles; Thapsigargin	2006
NAADP controls cross-talk between distinct Ca2+ stores in the heart. The Journal of biological chemistry, 2007, May-18, Volume: 282, Issue:20 Topics: Action Potentials; Animals; Calcium; Calcium Channels; Enzyme Inhibitors; Guinea Pigs; Heart Ventricles; Ion Channel Gating; Macrolides; Myocytes, Cardiac; NADP; Proton-Translocating ATPases; Receptors, Adrenergic, beta; Ryanodine; Sarcolemma; Thapsigargin	2007
NAADP mobilizes calcium from the endoplasmic reticular Ca(2+) store in T-lymphocytes. The Journal of biological chemistry, 2007, Jun-29, Volume: 282, Issue:26 Topics: Calcium; Calcium Signaling; Endoplasmic Reticulum; Enzyme Inhibitors; Humans; Jurkat Cells; Lysosomes; Macrolides; NADP; T-Lymphocytes; Thapsigargin	2007
The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores. Pflugers Archiv : European journal of physiology, 2009, Volume: 458, Issue:5 Topics: Amino Acid Sequence; Animal Structures; Animals; Calcium; Calcium Channels; Calcium Signaling; Cell Line; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Endoplasmic Reticulum; Enzyme Inhibitors; Glycosylation; Humans; Ion Channel Gating; Lysosomal-Associated Membrane Protein 1; Lysosomes; Mice; Mice, Inbred Strains; Molecular Sequence Data; NADP; Sequence Homology, Amino Acid; Thapsigargin; Transfection; Vacuolar Proton-Translocating ATPases	2009
Monitoring the intracellular store Ca2+ concentration in agonist-stimulated, intact human platelets by using Fluo-5N. Journal of thrombosis and haemostasis : JTH, 2011, Volume: 9, Issue:3 Topics: Blood Platelets; Calcium; Calcium Signaling; Fluorescent Dyes; Fura-2; Humans; Hydroquinones; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Ionomycin; Microscopy, Confocal; NADP; Nigericin; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Thrombin	2011
Arachidonic acid mobilizes Ca2+ from the endoplasmic reticulum and an acidic store in rat pancreatic β cells. Cell calcium, 2012, Volume: 51, Issue:2 Topics: Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Calcium Channel Agonists; Calcium Signaling; Cells, Cultured; Endoplasmic Reticulum; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate Receptors; Insulin-Secreting Cells; Macrolides; Male; NADP; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Secretory Vesicles; Thapsigargin; TRPM Cation Channels	2012
Organelle-specific subunit interactions of the vertebrate two-pore channel family. The Journal of biological chemistry, 2015, Jan-09, Volume: 290, Issue:2 Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Chickens; Endoplasmic Reticulum; Endosomes; Gene Expression Regulation; HEK293 Cells; Humans; Lysosomes; Macrolides; NADP; Rabbits; Thapsigargin	2015
A novel Ca²⁺-mediated cross-talk between endoplasmic reticulum and acidic organelles: implications for NAADP-dependent Ca²⁺ signalling. Cell calcium, 2015, Volume: 57, Issue:2 Topics: Calcium; Calcium Signaling; Dipeptides; Endoplasmic Reticulum; Endosomes; HeLa Cells; Humans; Lysosomes; Macrolides; Membrane Potentials; NADP; Nigericin; Patch-Clamp Techniques; Thapsigargin; TRPM Cation Channels	2015