Page last updated: 2024-09-03

naadp and inositol 1,4,5-trisphosphate

naadp has been researched along with inositol 1,4,5-trisphosphate in 62 studies

Compound Research Comparison

Studies (naadp)	Trials (naadp)	Recent Studies (post-2010) (naadp)	Studies (inositol 1,4,5-trisphosphate)	Trials (inositol 1,4,5-trisphosphate)	Recent Studies (post-2010) (inositol 1,4,5-trisphosphate)
411	0	184	6,600	1	589

Protein Interaction Comparison

Protein	Taxonomy	inositol 1,4,5-trisphosphate (IC50)
Inositol-trisphosphate 3-kinase A	Rattus norvegicus (Norway rat)	4.45
Inositol 1,4,5-trisphosphate receptor type 2	Homo sapiens (human)	0.03
Inositol 1,4,5-trisphosphate receptor type 3	Homo sapiens (human)	0.03
Inositol 1,4,5-trisphosphate receptor type 1	Homo sapiens (human)	0.03

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (16.13)	18.2507
2000's	39 (62.90)	29.6817
2010's	13 (20.97)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Beers, KW; Chini, CC; Chini, EN; Dousa, TP	1
Aarhus, R; Lee, HC	1
Chini, EN; Clapham, DE; Dousa, TP; Perez-Terzic, CM; Shen, SS	1
Galione, A; Genazzani, AA	1
Albrieux, M; Lee, HC; Villaz, M	1
Biancani, P	1
Dobashi, K; Horie, T; Iizuka, K; Mori, M; Nakazawa, T; Yoshii, A	1
Dubé, F; Eckberg, WR; Galione, A; Thomas, TW	1
Cancela, JM; Churchill, GC; Galione, A	1
Chini, EN; Dousa, TP	1
Gylfe, E; Hellman, B; Tengholm, A	1
Cancela, JM; Gerasimenko, JV; Gerasimenko, OV; Petersen, OH; Tepikin, AV	1
Berg, I; Guse, AH; Mayr, GW; Potter, BV	1
Churchill, GC; Galione, A	2
Churchill, GC; Galione, A; Patel, S	1
da Silva, CP; Guse, AH	1
Cheng, J; Chini, EN; Grande, JP; Thompson, MA; Yusufi, AN	1
Gallacher, DV; Harmer, AR; Smith, PM	1
Cancela, JM	1
Li, X; Mohanty, MJ; Rossi, NF; Ye, M	1
Brailoiu, E; Dun, NJ; Miyamoto, MD	1
Carafoli, E; Gragnaniello, G; Kyozuka, K; Lim, D; Santella, L	1
Grafton, G; Thwaite, L	1
Baux, G; Chameau, P; Fossier, P; Van de Vrede, Y	1
Burnett, JC; Cheng, J; Grande, JP; Thompson, MA; Yusufi, AN	1
Gobel, A; Krause, E; Schulz, I	1
Cancela, JM; Galione, A; Petersen, OH; Tepikin, AV; Van Coppenolle, F	1
Chini, EN	1
Li, X; Mohanty, MJ	1
Berridge, G; Dickinson, G; Galione, A; Parrington, J; Patel, S	1
Pivovarov, AS; Walker, RJ	1
Brailoiu, E; Dun, NJ; Patel, S	1
Dolman, NJ; Gerasimenko, JV; Gerasimenko, OV; Maruyama, Y; Petersen, OH; Tepikin, AV; Yano, K	1
Krause, E; Schulz, I	1
Gerasimenko, J; Gerasimenko, O	1
Guse, AH; Langhorst, MF; Schwarzmann, N	1
Lim, D; Moccia, F; Santella, L	1
Epel, D; Kuo, RC; Patton, C; Preston, CM; Thaler, CD; Yagisawa, H	1
Heidemann, AC; Kettenmann, H; Schipke, CG	1
López, JJ; Pariente, JA; Redondo, PC; Rosado, JA; Salido, GM	1
Churchill, GC; Galione, A; Yamasaki, M	1
Gerasimenko, JV; Gerasimenko, OV; Petersen, OH; Sherwood, M; Tepikin, AV	1
Chini, EN; Galione, A; Isbell, A; Lund, FE; Prakash, Y; Soares, S; Thompson, M; White, T; Yamasaki, M	1
Burdakov, A; Cancela, JM; Charpentier, G; Menteyne, A; Petersen, OH	1
Deguchi, R	1
Bodrato, N; Bruzzone, S; De Flora, A; Guida, L; Kassack, MU; Moreschi, I; Nicholas, RA; Usai, C; Zocchi, E	1
Baux, G; Bezin, S; Cancela, JM; Charpentier, G; Fossier, P; Lee, HC	1
Arredouani, A; Churchill, GC; Galione, A; Ganesan, A; Izumi, M; Lewis, AM; Mizote, A; Naylor, E; Parkesh, R; Rosen, D; Thomas, JM; Vasudevan, SR	1
Cho, BH; Kim, SY; Kim, UH	1
Brading, A; Chuang, KT; Galione, A; Parrington, J; Ruas, M; Tugba Durlu-Kandilci, N	1
Brailoiu, E; Dun, NJ; Friedman, G; Gogotsi, Y; Orynbayeva, Z; Vitol, EA	1
Aley, PK; Berger, F; Churchill, GC; Galione, A; Mikolajczyk, AM; Munz, B	1
Kim, UH; Mushtaq, M; Nam, TS	1
Lee, HC	1
Bloor-Young, D; Cerundolo, V; Chen, JL; Churchill, GC; Conway, SJ; Davis, LC; Galione, A; Morgan, AJ; Parrington, J; Shenderov, E; Snead, CM; Stanton-Humphreys, MN	1
Wu, H	1
Chuang, KT; Churchill, GC; Davis, LC; Funnell, TM; Galione, A; Morgan, AJ; Parrington, J; Ruas, M	1
López Sanjurjo, CI; Taylor, CW; Tovey, SC	1
Molinari, G	1
Mills, SJ; Potter, BV; Riley, AM; Swarbrick, JM	1
Kyozuka, K; Takahashi, I	1

Reviews

10 review(s) available for naadp and inositol 1,4,5-trisphosphate

Article	Year
Intracellular Ca(2+) release mechanisms: multiple pathways having multiple functions within the same cell type? Biochimica et biophysica acta, 2000, Dec-20, Volume: 1498, Issue:2-3 Topics: Adenosine Diphosphate Ribose; Animals; Biological Evolution; Calcium; Cell Line; Cyclic ADP-Ribose; Humans; Inositol 1,4,5-Trisphosphate; NADP; Second Messenger Systems; Signal Transduction	2000
Specific Ca2+ signaling evoked by cholecystokinin and acetylcholine: the roles of NAADP, cADPR, and IP3. Annual review of physiology, 2001, Volume: 63 Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Calcium Signaling; Cholecystokinin; Cyclic ADP-Ribose; Humans; Inositol 1,4,5-Trisphosphate; NADP	2001
Calcium channels in lymphocytes. Immunology, 2001, Volume: 104, Issue:2 Topics: Calcium Channels; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lymphocyte Subsets; NADP; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Ryanodine Receptor Calcium Release Channel	2001
Inositol 1,4,5-trisphosphate and its co-players in the concert of Ca2+ signalling--new faces in the line up. Current molecular medicine, 2004, Volume: 4, Issue:3 Topics: Calcium Signaling; Cyclic ADP-Ribose; Inositol 1,4,5-Trisphosphate; NADP	2004
New aspects of nuclear calcium signalling. Journal of cell science, 2004, Jul-01, Volume: 117, Issue:Pt 15 Topics: Animals; Calcium; Cell Nucleus; Cyclic ADP-Ribose; Endoplasmic Reticulum; Humans; Inositol 1,4,5-Trisphosphate; Lysosomes; Models, Biological; NADP; Pancreas; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Thapsigargin	2004
Calcium and fertilization: the beginning of life. Trends in biochemical sciences, 2004, Volume: 29, Issue:8 Topics: Animals; Calcium; Calcium Signaling; Fertilization; Humans; Inositol 1,4,5-Trisphosphate; NADP	2004
Calcium signalling by nicotinic acid adenine dinucleotide phosphate (NAADP). The FEBS journal, 2005, Volume: 272, Issue:18 Topics: Animals; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Humans; Inositol 1,4,5-Trisphosphate; NADP; Second Messenger Systems	2005
Cyclic ADP-ribose and NAADP: fraternal twin messengers for calcium signaling. Science China. Life sciences, 2011, Volume: 54, Issue:8 Topics: ADP-ribosyl Cyclase 1; Animals; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Endoplasmic Reticulum; Humans; Inositol 1,4,5-Trisphosphate; Lysosomes; Models, Molecular; Molecular Structure; NADP; Protein Conformation; Ryanodine Receptor Calcium Release Channel	2011
[Calcium signaling in platelet activation]. Sheng li ke xue jin zhan [Progress in physiology], 2012, Volume: 43, Issue:6 Topics: Calcium; Calcium Channels; Calcium Signaling; Humans; Inositol 1,4,5-Trisphosphate; Membrane Proteins; NADP; Neoplasm Proteins; ORAI1 Protein; Platelet Activation; Stromal Interaction Molecule 1	2012
Designer small molecules to target calcium signalling. Biochemical Society transactions, 2015, Volume: 43, Issue:3 Topics: Adenosine; Adenosine Diphosphate Ribose; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Calcium Signaling; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; NADP; Ryanodine Receptor Calcium Release Channel; Small Molecule Libraries; Structure-Activity Relationship	2015

Other Studies

52 other study(ies) available for naadp and inositol 1,4,5-trisphosphate

Article	Year
Specific modulation of cyclic ADP-ribose-induced Ca2+ release by polyamines. The American journal of physiology, 1995, Volume: 269, Issue:4 Pt 1 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cyclic ADP-Ribose; Inositol 1,4,5-Trisphosphate; NADP; Ovum; Polyamines; Ryanodine; Sea Urchins; Spermine	1995
A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose. The Journal of biological chemistry, 1995, Feb-03, Volume: 270, Issue:5 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Magnetic Resonance Spectroscopy; Microsomes; NADP; Ovum; Sea Urchins	1995
Ca2+ release triggered by nicotinate adenine dinucleotide phosphate in intact sea urchin eggs. The Biochemical journal, 1995, Dec-15, Volume: 312 ( Pt 3) Topics: Animals; Calcium; Female; Fertilization; Heparin; Inositol 1,4,5-Trisphosphate; Microinjections; Microscopy, Confocal; NADP; Ovum; Sea Urchins	1995
Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive pool. The Biochemical journal, 1996, May-01, Volume: 315 ( Pt 3) Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Cyclic ADP-Ribose; Drug Resistance; Enzyme Inhibitors; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ion Transport; NADP; Organelles; Ovum; Sea Urchins; Terpenes; Thapsigargin	1996
Calcium signaling by cyclic ADP-ribose, NAADP, and inositol trisphosphate are involved in distinct functions in ascidian oocytes. The Journal of biological chemistry, 1998, Jun-05, Volume: 273, Issue:23 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Calcium; Chelating Agents; Cyclic ADP-Ribose; Electrophysiology; Fertilization; Inositol 1,4,5-Trisphosphate; NAD; NAD+ Nucleosidase; NADP; Oocytes; Patch-Clamp Techniques; Ryanodine; Signal Transduction; Urochordata	1998
Diversity of Ca(2+)-mobilizing mechanisms focus on "cGMP-mediated Ca2+ release from IP3-insensitive Ca2+ stores in smooth muscle". The American journal of physiology, 1998, Volume: 274, Issue:5 Topics: Adenosine Diphosphate Ribose; Animals; Biological Transport; Calcium; Cyclic ADP-Ribose; Cyclic GMP; Inositol 1,4,5-Trisphosphate; Muscle, Smooth; NADP	1998
InsP3, but not novel Ca2+ releasers, contributes to agonist-initiated contraction in rabbit airway smooth muscle. The Journal of physiology, 1998, Sep-15, Volume: 511 ( Pt 3) Topics: Adenosine Diphosphate Ribose; Administration, Topical; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Anticoagulants; Bronchi; Caffeine; Calcium; Carbachol; Central Nervous System Stimulants; Dimethyl Sulfoxide; Guanosine Triphosphate; Guinea Pigs; Heparin; Humans; Ileum; Immunosuppressive Agents; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth; NADP; Parasympathomimetics; Procaine; Rabbits; Ryanodine; Species Specificity; Tacrolimus; Trachea; Type C Phospholipases	1998
Mechanisms of calcium release and sequestration in eggs of Chaetopterus pergamentaceus. Cell calcium, 1998, Volume: 24, Issue:4 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Extracts; Cyclic ADP-Ribose; Female; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Male; NADP; Ovum; Polychaeta; Receptors, Cytoplasmic and Nuclear; Ryanodine; Spermatozoa; Thapsigargin; Thimerosal	1998
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells. Nature, 1999, Mar-04, Volume: 398, Issue:6722 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Mice; NADP; Pancreas; Sea Urchins	1999
Differential effect of glycolytic intermediaries upon cyclic ADP-ribose-, inositol 1',4',5'-trisphosphate-, and nicotinate adenine dinucleotide phosphate-induced Ca(2+) release systems. Archives of biochemistry and biophysics, 1999, Oct-15, Volume: 370, Issue:2 Topics: Adenosine Diphosphate Ribose; Animals; Calcium Signaling; Cyclic ADP-Ribose; Female; Fructosediphosphates; Glycolysis; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; NADP; Oocytes; Ryanodine Receptor Calcium Release Channel; Sea Urchins	1999
Mobilization of Ca2+ stores in individual pancreatic beta-cells permeabilized or not with digitonin or alpha-toxin. Cell calcium, 2000, Volume: 27, Issue:1 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Bacterial Toxins; Caffeine; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Compartmentation; Cell Membrane Permeability; Cyclic ADP-Ribose; Cytoplasm; Digitonin; Enzyme Inhibitors; Hemolysin Proteins; Inositol 1,4,5-Trisphosphate; Ionophores; Islets of Langerhans; Mice; Mice, Obese; NADP; Organelles; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin	2000
Two different but converging messenger pathways to intracellular Ca(2+) release: the roles of nicotinic acid adenine dinucleotide phosphate, cyclic ADP-ribose and inositol trisphosphate. The EMBO journal, 2000, Jun-01, Volume: 19, Issue:11 Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Calcium Signaling; Cell Line; Cholecystokinin; Cyclic ADP-Ribose; Drug Synergism; Endoplasmic Reticulum; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Ion Transport; Mice; NADP; Pancreas; Patch-Clamp Techniques; Receptors, Cell Surface; Receptors, Cholecystokinin; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel	2000
Nicotinic acid adenine dinucleotide phosphate (NAADP(+)) is an essential regulator of T-lymphocyte Ca(2+)-signaling. The Journal of cell biology, 2000, Aug-07, Volume: 150, Issue:3 Topics: Adenosine Diphosphate Ribose; Calcium Signaling; CD3 Complex; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Humans; Image Processing, Computer-Assisted; Inositol 1,4,5-Trisphosphate; Jurkat Cells; Lymphocyte Activation; Microinjections; NADP; Receptors, Antigen, T-Cell; Ryanodine Receptor Calcium Release Channel; T-Lymphocytes	2000
Spatial control of Ca2+ signaling by nicotinic acid adenine dinucleotide phosphate diffusion and gradients. The Journal of biological chemistry, 2000, Dec-08, Volume: 275, Issue:49 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Diffusion; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; NADP; Oocytes; Sea Urchins	2000
Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhance the sensitivity of NAADP receptors for their ligand. The Biochemical journal, 2000, Dec-15, Volume: 352 Pt 3 Topics: Adenosine Diphosphate Ribose; Animals; Binding Sites; Calcium; Calcium Signaling; Cell Extracts; Cyclic ADP-Ribose; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; NADP; Ovum; Protein Binding; Sea Urchins; Sodium Chloride	2000
Nicotinic acid-adenine dinucleotide phosphate (NAADP) elicits specific microsomal Ca2+ release from mammalian cells. The Biochemical journal, 2001, Feb-01, Volume: 353, Issue:Pt 3 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cells, Cultured; Cyclic ADP-Ribose; Glomerular Mesangium; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Microsomes; NADP; Radioligand Assay; Rats; Rats, Sprague-Dawley; Ryanodine	2001
Role of Ins(1,4,5)P3, cADP-ribose and nicotinic acid-adenine dinucleotide phosphate in Ca2+ signalling in mouse submandibular acinar cells. The Biochemical journal, 2001, Feb-01, Volume: 353, Issue:Pt 3 Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Calcium Signaling; Cyclic ADP-Ribose; Inositol 1,4,5-Trisphosphate; Male; Mice; NADP; Submandibular Gland	2001
NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ stores. The EMBO journal, 2001, Jun-01, Volume: 20, Issue:11 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Calcium Signaling; Cyclic ADP-Ribose; Female; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Models, Biological; NADP; Oocytes; Oscillometry; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Thapsigargin	2001
Hypotonic swelling-induced Ca(2+) release by an IP(3)-insensitive Ca(2+) store. American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:2 Topics: Animals; Calcium; Cell Line; Enzyme Inhibitors; Hypotonic Solutions; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Muscle, Smooth, Vascular; NADP; Osmolar Concentration; Ryanodine; Thapsigargin	2001
Nicotinic acid adenine dinucleotide phosphate enhances quantal neurosecretion at the frog neuromuscular junction: possible action on synaptic vesicles in the releasable pool. Molecular pharmacology, 2001, Volume: 60, Issue:4 Topics: Adenosine Diphosphate Ribose; Animals; Calcimycin; Cyclic ADP-Ribose; Drug Interactions; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; NADP; Neuromuscular Junction; Neurosecretion; Rana pipiens; Synaptic Vesicles; Thapsigargin	2001
NAADP+ initiates the Ca2+ response during fertilization of starfish oocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:12 Topics: Animals; Calcium Signaling; Cell Nucleus; Cells, Cultured; Exocytosis; Fertilization; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Maturation-Promoting Factor; Microscopy, Confocal; NADP; Oocytes; Spermatozoa; Starfish	2001
Ryanodine-, IP3- and NAADP-dependent calcium stores control acetylcholine release. Pflugers Archiv : European journal of physiology, 2001, Volume: 443, Issue:2 Topics: Acetylcholine; Animals; Aplysia; Biological Transport; Calcium; Cheek; Ganglia; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; NADP; Ryanodine; Ryanodine Receptor Calcium Release Channel; Synaptic Transmission	2001
Differential mechanisms of Ca(2+) release from vascular smooth muscle cell microsomes. Experimental biology and medicine (Maywood, N.J.), 2002, Volume: 227, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cells, Cultured; Cyclic ADP-Ribose; Inositol 1,4,5-Trisphosphate; Male; Microsomes; Muscle, Smooth, Vascular; NADP; Rats; Rats, Sprague-Dawley; Signal Transduction	2002
Cell side-specific sensitivities of intracellular Ca2+ stores for inositol 1,4,5-trisphosphate, cyclic ADP-ribose, and nicotinic acid adenine dinucleotide phosphate in permeabilized pancreatic acinar cells from mouse. The Journal of biological chemistry, 2002, Apr-05, Volume: 277, Issue:14 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cell Membrane; Cyclic ADP-Ribose; Cytoplasm; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; Heparin; Inositol 1,4,5-Trisphosphate; Mice; Microscopy, Confocal; Models, Biological; NADP; Pancreas; Protein Binding	2002
Transformation of local Ca2+ spikes to global Ca2+ transients: the combinatorial roles of multiple Ca2+ releasing messengers. The EMBO journal, 2002, Mar-01, Volume: 21, Issue:5 Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium Channels; Calcium Signaling; Cell Polarity; Cholecystokinin; Cyclic ADP-Ribose; Exocytosis; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; NADP; Pancreas; Patch-Clamp Techniques; Receptors, Cell Surface; Receptors, Cholecystokinin; Receptors, Cholinergic; Receptors, Cytoplasmic and Nuclear; Second Messenger Systems; Sincalide	2002
Interactions between intracellular Ca2+ stores: Ca2+ released from the NAADP pool potentiates cADPR-induced Ca2+ release. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2002, Volume: 35, Issue:5 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Inositol 1,4,5-Trisphosphate; NADP; Ovum; Sea Urchins	2002
Stretch-induced Ca(2+) release via an IP(3)-insensitive Ca(2+) channel. American journal of physiology. Cell physiology, 2002, Volume: 283, Issue:2 Topics: Actins; Animals; Calcium; Calcium Channels; Cell Line; Cytochalasin D; Drug Resistance; Gadolinium; Heparin; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Ion Channels; Lanthanum; Microtubules; NADP; Nocodazole; Ryanodine; Stress, Mechanical	2002
Solubilization of receptors for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate. The Journal of biological chemistry, 2002, Nov-15, Volume: 277, Issue:46 Topics: Animals; Calcium; Centrifugation, Density Gradient; Chromatography, Gel; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Inositol 1,4,5-Trisphosphate; Ligands; NADP; Octoxynol; Protein Binding; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Sucrose; Time Factors	2002
EPYLRFamide-mediated reduction of acetylcholine-induced inward currents in Helix lucorum-identified neurones: role of NAADP-dependent and IP3-dependent Ca2+ release from internal stores, calmodulin and Ca2+/calmodulin-dependent protein kinase II. Regulatory peptides, 2003, Mar-28, Volume: 111, Issue:1-3 Topics: Acetylcholine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Electrophysiology; Enzyme Inhibitors; Helix, Snails; Heparin; Inositol 1,4,5-Trisphosphate; NADP; Neurons; Neuropeptides; Patch-Clamp Techniques; Receptors, Cholinergic; Receptors, Thrombin	2003
Modulation of spontaneous transmitter release from the frog neuromuscular junction by interacting intracellular Ca(2+) stores: critical role for nicotinic acid-adenine dinucleotide phosphate (NAADP). The Biochemical journal, 2003, Jul-15, Volume: 373, Issue:Pt 2 Topics: Animals; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Electrophysiology; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Muscles; NADP; Neuromuscular Junction; Neurotransmitter Agents; Phosphorylcholine; Rana pipiens; Sphingosine; Thapsigargin; Wound Healing	2003
NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors. The Journal of cell biology, 2003, Oct-27, Volume: 163, Issue:2 Topics: Animals; Calcium; Cyclic ADP-Ribose; Fluorescent Dyes; Inositol 1,4,5-Trisphosphate; Mice; Mice, Inbred Strains; Models, Biological; NADP; Nuclear Envelope; Pancreas; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin	2003
Ca2+ release via ryanodine receptors and Ca2+ entry: major mechanisms in NAADP-mediated Ca2+ signaling in T-lymphocytes. Cellular signalling, 2004, Volume: 16, Issue:11 Topics: Calcium; Calcium Channel Blockers; Calcium Signaling; Down-Regulation; Gadolinium; Heparin; Humans; Inositol 1,4,5-Trisphosphate; Jurkat Cells; Lymphocyte Activation; NADP; RNA, Antisense; Ruthenium Red; Ryanodine Receptor Calcium Release Channel; Signal Transduction; T-Lymphocytes; Transfection	2004
Phosphoinositide metabolism at fertilization of sea urchin eggs measured with a GFP-probe. Development, growth & differentiation, 2004, Volume: 46, Issue:5 Topics: Animals; Base Sequence; Calcium; Cyclic ADP-Ribose; DNA Primers; Green Fluorescent Proteins; Inositol 1,4,5-Trisphosphate; Lytechinus; Molecular Probes; NADP; Ovum; Phosphatidylinositols; Type C Phospholipases	2004
Extracellular application of nicotinic acid adenine dinucleotide phosphate induces Ca2+ signaling in astrocytes in situ. The Journal of biological chemistry, 2005, Oct-21, Volume: 280, Issue:42 Topics: Adenosine; ADP-ribosyl Cyclase 1; Animals; Astrocytes; Calcium; Cell Line, Tumor; Central Nervous System; Cerebellum; Connexins; Immunohistochemistry; Inositol 1,4,5-Trisphosphate; Lysosomes; Mice; Models, Biological; NADP; Neurons; Oligodendroglia; Signal Transduction; Time Factors	2005
Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets. Cellular signalling, 2006, Volume: 18, Issue:3 Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Compartmentation; Estrenes; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Isoenzymes; NADP; Nimodipine; Pyrrolidinones; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Thrombin; Type C Phospholipases; Vasopressins	2006
NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area. Journal of cell science, 2006, Jan-15, Volume: 119, Issue:Pt 2 Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Cyclic ADP-Ribose; Endoplasmic Reticulum; Enzyme Inhibitors; Fluorescent Dyes; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Ionophores; Macrolides; Mice; NADP; Nigericin; Pancreas; Secretory Vesicles; Thapsigargin	2006
NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells. American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:1 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Calcium; Cells, Cultured; Female; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Lysosomes; Mice; Mice, Inbred C57BL; Mice, Knockout; Myometrium; NADP; Ryanodine Receptor Calcium Release Channel; Second Messenger Systems; Signal Transduction	2007
Generation of specific Ca(2+) signals from Ca(2+) stores and endocytosis by differential coupling to messengers. Current biology : CB, 2006, Oct-10, Volume: 16, Issue:19 Topics: Acetylcholine; Animals; Calcium; Calcium Signaling; Cells, Cultured; Cholecystokinin; Cyclic ADP-Ribose; Endocytosis; Endoplasmic Reticulum; Inositol 1,4,5-Trisphosphate; Lysosomes; NADP; Secretory Vesicles	2006
Fertilization causes a single Ca2+ increase that fully depends on Ca2+ influx in oocytes of limpets (Phylum Mollusca, Class Gastropoda). Developmental biology, 2007, Apr-15, Volume: 304, Issue:2 Topics: Animals; Caffeine; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Female; Fertilization; Gastropoda; Inositol 1,4,5-Trisphosphate; Male; Meiosis; NADP; Oocytes	2007
NAADP+ is an agonist of the human P2Y11 purinergic receptor. Cell calcium, 2008, Volume: 43, Issue:4 Topics: Animals; Calcium; Cell Line; Chemotaxis; Cyclic ADP-Ribose; Cyclic AMP; Granulocytes; Humans; Inositol 1,4,5-Trisphosphate; NADP; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Signal Transduction	2008
Regulation of nuclear Ca2+ signaling by translocation of the Ca2+ messenger synthesizing enzyme ADP-ribosyl cyclase during neuronal depolarization. The Journal of biological chemistry, 2008, Oct-10, Volume: 283, Issue:41 Topics: Active Transport, Cell Nucleus; ADP-ribosyl Cyclase; Animals; Aplysia; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Nucleus; Cyclic ADP-Ribose; Cytosol; Inositol 1,4,5-Trisphosphate; NADP; Neurons; Ryanodine Receptor Calcium Release Channel	2008
Identification of a chemical probe for NAADP by virtual screening. Nature chemical biology, 2009, Volume: 5, Issue:4 Topics: Animals; Carbolines; Cyclic ADP-Ribose; Inositol 1,4,5-Trisphosphate; Insulin-Secreting Cells; Mice; Models, Molecular; Molecular Structure; NADP; Ovum; Piperazines; Sea Urchins; Small Molecule Libraries	2009
CD38-mediated Ca2+ signaling contributes to angiotensin II-induced activation of hepatic stellate cells: attenuation of hepatic fibrosis by CD38 ablation. The Journal of biological chemistry, 2010, Jan-01, Volume: 285, Issue:1 Topics: ADP-ribosyl Cyclase 1; Angiotensin II; Animals; Calcium; Calcium Signaling; Cell Proliferation; Collagen Type I; Cyclic ADP-Ribose; Extracellular Matrix Proteins; Gene Deletion; Hepatic Stellate Cells; Inositol 1,4,5-Trisphosphate; Intracellular Space; Liver Cirrhosis; Mice; Models, Biological; NADP	2010
TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle. The Journal of biological chemistry, 2010, Aug-06, Volume: 285, Issue:32 Topics: Animals; Calcium; Calcium Channels; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; Gene Expression Profiling; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Lysosomes; Male; Mice; Muscle Contraction; Muscle, Smooth; NADP	2010
Surface-enhanced Raman spectroscopy as a tool for detecting Ca2+ mobilizing second messengers in cell extracts. Analytical chemistry, 2010, Aug-15, Volume: 82, Issue:16 Topics: Calcium; Calcium Signaling; Cell Line, Tumor; Cyclic ADP-Ribose; Gold; Humans; Inositol 1,4,5-Trisphosphate; Metal Nanoparticles; NADP; Second Messenger Systems; Spectrum Analysis, Raman	2010
Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channels. Proceedings of the National Academy of Sciences of the United States of America, 2010, Nov-16, Volume: 107, Issue:46 Topics: Acids; Animals; Calcium; Calcium Channels; Cell Differentiation; Cells, Cultured; Down-Regulation; Endoplasmic Reticulum; Inositol 1,4,5-Trisphosphate; Mice; Muscle, Skeletal; NADP; Ryanodine; Second Messenger Systems; Signal Transduction	2010
Critical role for CD38-mediated Ca2+ signaling in thrombin-induced procoagulant activity of mouse platelets and hemostasis. The Journal of biological chemistry, 2011, Apr-15, Volume: 286, Issue:15 Topics: ADP-ribosyl Cyclase 1; Animals; Blood Platelets; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Enzyme Inhibitors; Hemostasis; Hemostatics; Inositol 1,4,5-Trisphosphate; Macrolides; Membrane Glycoproteins; Mice; Mice, Knockout; NADP; Phosphatidylserines; Protein Kinase C; Thrombin	2011
NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing. Current biology : CB, 2012, Dec-18, Volume: 22, Issue:24 Topics: Animals; Cytoplasmic Granules; Exocytosis; Humans; Inositol 1,4,5-Trisphosphate; Lymphocyte Activation; NADP; T-Lymphocytes, Cytotoxic	2012
Preparation and use of sea urchin egg homogenates for studying NAADP-mediated Ca²⁺ release. Cold Spring Harbor protocols, 2014, Sep-02, Volume: 2014, Issue:9 Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Calcium; Calcium Signaling; Cell Fractionation; Female; Inositol 1,4,5-Trisphosphate; Male; NADP; Ovum; Sea Urchins; Xanthenes	2014
Rapid recycling of Ca2+ between IP3-sensitive stores and lysosomes. PloS one, 2014, Volume: 9, Issue:10 Topics: Calcium; Calcium Signaling; Carbachol; Cell Line; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lysosomes; NADP	2014
Is hydrogen ion (H(+)) the real second messenger in calcium signalling? Cellular signalling, 2015, Volume: 27, Issue:7 Topics: Adenosine Triphosphate; Calcium Signaling; Cyclic AMP; Cytosol; Humans; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Lysophospholipids; NADP; Second Messenger Systems; Sphingosine	2015
Development of Ca2+-release mechanisms during oocyte maturation of the starfish Asterina pectinifera. Zygote (Cambridge, England), 2016, Volume: 24, Issue:6 Topics: Adenine; Animals; Asterina; Calcium; Calcium Ionophores; Cytosol; Female; Fertilization in Vitro; Heparin; In Vitro Oocyte Maturation Techniques; Inositol 1,4,5-Trisphosphate; Ionomycin; Male; NADP; Oocytes; Sperm-Ovum Interactions	2016