n-succinimidyl-4-fluorobenzoate and 4-fluorobenzoic-acid

n-succinimidyl-4-fluorobenzoate has been researched along with 4-fluorobenzoic-acid* in 1 studies

Other Studies

1 other study(ies) available for n-succinimidyl-4-fluorobenzoate and 4-fluorobenzoic-acid

ArticleYear
Fully automated preparation of n.c.a. 4-[18F]fluorobenzoic acid and N-succinimidyl 4-[18F]fluorobenzoate using a Siemens/CTI chemistry process control unit (CPCU).
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2007, Volume: 65, Issue:2

    The widely used bifunctional labeling reagent 4-[18F]fluorobenzoic acid ([18F]FBA) and its activated form N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB) were prepared using a modified Siemens/CTI chemistry process control unit (CPCU) double vessel [18F]FDG module. The products were obtained with a radiochemical yield greater than 99% with decay corrected yields of 77+/-5% (n=4) for [18F]FBA and 46+/-5% (n=4) for [18F]SFB. The presented synthetic procedure is highly reproducible and fully automated.

    Topics: Benzoates; Fluorine Radioisotopes; Isotope Labeling; Radiopharmaceuticals; Succinimides

2007