Compounds > n-palmitoylglycine
Page last updated: 2024-09-04

n-palmitoylglycine and glycine

n-palmitoylglycine has been researched along with glycine in 12 studies

Compound Research Comparison

Studies
(n-palmitoylglycine)		Trials
(n-palmitoylglycine)		Recent Studies (post-2010)
(n-palmitoylglycine)		Studies
(glycine)		Trials
(glycine)		Recent Studies (post-2010) (glycine)
180635,1637568,415

Protein Interaction Comparison

ProteinTaxonomyn-palmitoylglycine (IC50)glycine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.4852
Sodium- and chloride-dependent glycine transporter 1Homo sapiens (human)106
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.3253
Sodium- and chloride-dependent glycine transporter 2Homo sapiens (human)128

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's9 (75.00)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vamvakidès, A1
Haines, DC; Machius, M; Peterson, JA; Tomchick, DR1
Boland, W; Bossi, S; Maffei, M; Mithöfer, A; Spiteller, D1
Friesner, RA; Gallicchio, E; Levy, RM; McDermott, AE; Ravindranathan, KP1
Gallicchio, E; Levy, RM; McDermott, AE; Ravindranathan, KP1
Brenner, S; Girvan, HM; Hay, S; Munro, AW; Scrutton, NS1
Bradshaw, HB; Burstein, S; Chen, JS; Cravatt, BF; Hu, SS; Hughes, HV; Jahnsen, JA; Masuda, K; McHugh, D; O'Dell, DK; Prieto, AL; Rimmerman, N; Thompson, EL; Vasko, MR; Vefring, E; Walker, JM1
Chowdhary, PK; Haines, DC; Lopez, C; Stewart, L1
Bradshaw, HB; Lee, SH; McHugh, D1
Bradshaw, HB; Burstein, S; Hu, SS; Rimmerman, N; Walker, JM1
Bradshaw, HB; Hollis, JL; Raboune, S1
Brown, AJ; Chen, MX; Dowell, SJ; Foster, JR; Harvey, J; Irving, AJ; Ueno, S1

Reviews

3 review(s) available for n-palmitoylglycine and glycine

ArticleYear
Orphan endogenous lipids and orphan GPCRs: a good match.
    Prostaglandins & other lipid mediators, 2009, Volume: 89, Issue:3-4

    Topics: Amides; Animals; Fatty Acids; Glycine; Humans; Lipid Metabolism; Lipids; Palmitic Acids; Polyisoprenyl Phosphates; Protein Isoforms; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Research Design; Sesquiterpenes; Signal Transduction

2009
Novel endogenous N-acyl glycines identification and characterization.
    Vitamins and hormones, 2009, Volume: 81

    Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Glycine; Humans; Molecular Structure; Palmitic Acids; Signal Transduction

2009
Opportunistic activation of TRP receptors by endogenous lipids: exploiting lipidomics to understand TRP receptor cellular communication.
    Life sciences, 2013, Mar-19, Volume: 92, Issue:8-9

    Topics: Cell Communication; Glycine; Humans; Lipids; Metabolomics; Palmitic Acids; Transient Receptor Potential Channels

2013

Other Studies

9 other study(ies) available for n-palmitoylglycine and glycine

ArticleYear
[Pharmacologic profile of n-palmitoylglycine. Its effect on reserpine and haloperidol catalepsy].
    Bollettino chimico farmaceutico, 1995, Volume: 134, Issue:5

    Topics: Animals; Catalepsy; Glycine; Haloperidol; Male; Mice; Palmitic Acids; Rats; Reserpine

1995
Pivotal role of water in the mechanism of P450BM-3.
    Biochemistry, 2001, Nov-13, Volume: 40, Issue:45

    Topics: Bacillus megaterium; Bacterial Proteins; Binding Sites; Binding, Competitive; Crystallization; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Glycine; Heme; Mixed Function Oxygenases; Models, Molecular; NADPH-Ferrihemoprotein Reductase; Palmitic Acids; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity; Water

2001
Effects of feeding Spodoptera littoralis on lima bean leaves. I. Membrane potentials, intracellular calcium variations, oral secretions, and regurgitate components.
    Plant physiology, 2004, Volume: 134, Issue:4

    Topics: alpha-Linolenic Acid; Animals; Bodily Secretions; Calcium; Calcium Channel Blockers; Fabaceae; Feeding Behavior; Glutamine; Glycine; Glycine max; Immunity, Innate; Insect Bites and Stings; Larva; Palmitic Acids; Plant Diseases; Plant Leaves; Signal Transduction; Spodoptera; Stress, Mechanical; Verapamil

2004
Conformational equilibrium of cytochrome P450 BM-3 complexed with N-palmitoylglycine: a replica exchange molecular dynamics study.
    Journal of the American Chemical Society, 2006, May-03, Volume: 128, Issue:17

    Topics: Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Glycine; Models, Molecular; Palmitic Acids; Spectrophotometry, Ultraviolet; Temperature

2006
Conformational dynamics of substrate in the active site of cytochrome P450 BM-3/NPG complex: insights from NMR order parameters.
    Journal of the American Chemical Society, 2007, Jan-24, Volume: 129, Issue:3

    Topics: Algorithms; Bacillus megaterium; Bacterial Proteins; Binding Sites; Computer Simulation; Cytochrome P-450 Enzyme System; Glycine; Magnetic Resonance Spectroscopy; Palmitic Acids; Protein Conformation; Protein Engineering; Temperature

2007
Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed "proximal-distal" transition probed by temperature-jump spectroscopy.
    The journal of physical chemistry. B, 2007, Jul-12, Volume: 111, Issue:27

    Topics: Algorithms; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Glycine; Heme; Iron; Magnetic Resonance Spectroscopy; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Palmitic Acids; Phenylalanine; Protein Conformation; Spectrophotometry, Ultraviolet; Spectrum Analysis

2007
N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons.
    Molecular pharmacology, 2008, Volume: 74, Issue:1

    Topics: Amidohydrolases; Animals; Antibodies; Benzamides; Brain Chemistry; Calcium; Carbamates; Cell Line; Crosses, Genetic; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Female; Ganglia, Spinal; Glycine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; Nitric Oxide; Nociceptors; Palmitic Acids; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Tissue Distribution; Up-Regulation

2008
A single mutation in P450BM-3 enhances acyl homoserine lactone: acyl homoserine substrate binding selectivity nearly 250-fold.
    Journal of biotechnology, 2008, Jul-31, Volume: 135, Issue:4

    Topics: Acyl-Butyrolactones; Arginine; Bacillus megaterium; Bacterial Proteins; Cytochrome P-450 Enzyme System; Glycine; Homoserine; Kinetics; Mutation; NADPH-Ferrihemoprotein Reductase; Palmitic Acids; Spectrophotometry, Ultraviolet; Substrate Specificity

2008
    Pharmacology research & perspectives, 2019, Volume: 7, Issue:6

    Topics: Animals; Cell Cycle Proteins; CHO Cells; Cricetulus; Cyclohexanols; Drug Antagonism; Fatty Acids, Unsaturated; Glycine; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Palmitic Acids; Peptidomimetics; Receptors, G-Protein-Coupled; Recombinant Proteins; Signal Transduction; Structural Homology, Protein; Telmisartan

2019