Compounds > n-nitroso-n(2)-fluorenylacetamide
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n-nitroso-n(2)-fluorenylacetamide and 2-acetylaminofluorene

n-nitroso-n(2)-fluorenylacetamide has been researched along with 2-acetylaminofluorene in 8 studies

Compound Research Comparison

Studies
(n-nitroso-n(2)-fluorenylacetamide)		Trials
(n-nitroso-n(2)-fluorenylacetamide)		Recent Studies (post-2010)
(n-nitroso-n(2)-fluorenylacetamide)		Studies
(2-acetylaminofluorene)		Trials
(2-acetylaminofluorene)		Recent Studies (post-2010) (2-acetylaminofluorene)
8002,352097

Protein Interaction Comparison

ProteinTaxonomyn-nitroso-n(2)-fluorenylacetamide (IC50)2-acetylaminofluorene (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)2.143
Cytochrome P450 1A2Homo sapiens (human)0.016
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)8.595
Amine oxidase [flavin-containing] AHomo sapiens (human)0.059
Sodium-dependent noradrenaline transporter Homo sapiens (human)8.595
5-hydroxytryptamine receptor 2CHomo sapiens (human)2.143
Sodium-dependent serotonin transporterHomo sapiens (human)6.053
5-hydroxytryptamine receptor 2BHomo sapiens (human)3.17

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's6 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, JK; Tseng, SF1
Kuo, ML; Lin, JK3
Cheng, HT; Ho, YS; Lin, JK; Wang, YJ1
Ho, YS; Lin, JK2
Lin, JK; Lin-Shiau, SY; Wang, JM1

Other Studies

8 other study(ies) available for n-nitroso-n(2)-fluorenylacetamide and 2-acetylaminofluorene

ArticleYear
Chromosomal aberrations and sister-chromatid exchanges induced by N-nitroso-2-acetylaminofluorene and their modifications by arsenite and selenite in Chinese hamster ovary cells.
    Mutation research, 1992, Volume: 265, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Arsenic; Arsenites; Cell Cycle; CHO Cells; Chromosome Aberrations; Cricetinae; Drug Interactions; Mutagens; Nitroso Compounds; Selenium; Sister Chromatid Exchange; Sodium Selenite

1992
Induction of ouabain-resistance mutation and cycle-dependent transformation of C3H/10T1/2 cells by N-nitroso-2-acetylaminofluorene.
    Mutation research, 1990, Volume: 230, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Resistance; Half-Life; Mutagens; Mutation; Nitroso Compounds; Ouabain; Time Factors

1990
The relationship between DNA damage and mutation frequency in mammalian cell lines treated with N-nitroso-N-2-fluorenylacetamide.
    Mutation research, 1989, Volume: 212, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Cell Line; Cricetinae; DNA Damage; Dose-Response Relationship, Drug; Drug Administration Schedule; In Vitro Techniques; Mice; Mutation; Nitroso Compounds; Plasmids

1989
N-nitroso-N-2-fluorenylacetamide: a new direct-acting mutagen and teratogen.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Adenosine; Amino Acids; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Chromatography, High Pressure Liquid; Cytidine; DNA Damage; Glutathione; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylnitronitrosoguanidine; Methylnitrosourea; Mutation; Nitroso Compounds; Nucleosides; Salmonella typhimurium; Spectrophotometry, Infrared

1988
p53 gene mutational spectra in hepatocellular carcinomas induced by 2-acetylaminofluorene and N-nitroso-2-acetylaminofluorene in rats.
    Molecular carcinogenesis, 1995, Volume: 13, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Base Sequence; Cell Differentiation; DNA Primers; DNA, Neoplasm; Genes, p53; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Molecular Sequence Data; Nitroso Compounds; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Sprague-Dawley

1995
Preferential promutagenic lesions at exons 7-8 of human p53 genomic DNA induced by the direct-acting hepatocarcinogens N-nitroso-2-acetylaminofluorene and N-acetoxy-2-acetylaminofluorene.
    Cancer letters, 1995, Aug-16, Volume: 95, Issue:1-2

    Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; DNA Adducts; DNA Primers; Dose-Response Relationship, Drug; Exons; Genes, p53; Humans; In Vitro Techniques; Molecular Sequence Data; Mutation; Nitroso Compounds; Plasmids

1995
N-nitroso-2-acetylaminofluorene: a direct-acting carcinogen inducing hepatocellular carcinoma in Sprague-Dawley rats.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:8

    Topics: 2-Acetylaminofluorene; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Body Weight; Carcinogens; gamma-Glutamyltransferase; Glutathione Peroxidase; Glutathione Transferase; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Necrosis; Nitroso Compounds; Organ Size; Rats; Rats, Sprague-Dawley; Time Factors

1994
Relaxation of rat thoracic aorta by N-nitroso compounds and nitroprusside and their modifications of nucleic acid bases through release of nitric oxide.
    Biochemical pharmacology, 1993, Feb-24, Volume: 45, Issue:4

    Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Aorta, Thoracic; Deamination; Dose-Response Relationship, Drug; Female; Hemoglobins; Hydroxylation; Male; Methylene Blue; Methylnitronitrosoguanidine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Nitroso Compounds; Nucleic Acids; Rats; Rats, Wistar

1993