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n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and metallothionein

n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine has been researched along with metallothionein in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (11.54)18.2507
2000's16 (61.54)29.6817
2010's5 (19.23)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Leone, A; Moltedo, O; Remondelli, P1
Beyersmann, D; Schmidt, C1
Béani, JC; Favier, A; Meplan, C; Parat, MO; Richard, MJ1
Gandley, R; Levitan, ES; Pearce, LL; Pitt, BR; St Croix, CM; Wasserloos, K1
Hainaut, P; Méplan, C; Richard, MJ1
Bobo, JA; Cao, J; Cousins, RJ; Liuzzi, JP1
Dineley, KE; Levitan, ES; Pitt, BR; Reynolds, IJ; St Croix, CM; Wasserloos, KJ1
Chimienti, F; Favier, A; Seve, M1
Daniel, H; Döring, F; Kindermann, B; Pfaffl, M1
Brown, RW; Chung, MJ; Hogstrand, C; Walker, PA1
Black, SM; Hubbard, M; Welker, JE; Wells, SM; Wilham, J; Wiseman, DA1
Black, SM; Hubbard, M; Welker, JE; Wells, SM; Wiseman, DA1
Dughish, M; Kiekenbush, C; Krezoski, S; Krull, S; Meeusen, J; Petering, DH; Specher, T; Zhu, J1
Chung, MJ; Hogstrand, C; Lee, SJ1
Kothinti, R; Krezoski, S; Meeusen, J; Petering, DH; Rana, U; Tabatabai, NM1
Bush, AI; Colvin, RA; Fontaine, CP; Holmes, WR; Kikuchi, K; Thomas, D; Volitakis, I1
Bauer, E; Bernal, PJ; Cao, R; Leelavanichkul, K; Pitt, BR; St Croix, CM; Wasserloos, KJ; Watkins, SC; Wilson, A1
Barchowsky, A; Leikauf, GD; Nemec, AA; Pitt, BR; Wasserloos, KJ1
Caprini, V; Murgia, C; Perozzi, G; Ranaldi, G; Sambuy, Y1
Hao, J; Huang, K; Li, X; Luo, Y; Shen, XL; Xu, W; Yang, X; Zhang, Y; Zheng, J1
Knuhtsen, A; Larsen, A; Nygaard, SB; Rungby, J; Smidt, K1
Hwang, JJ; Jo, DG; Kim, JS; Koh, JY; Lee, JY; Oh, SB; Suh, N1
Holland, TC; Killilea, DW; King, JC; Shenvi, SV1
Kung, H; Ma, H; Miao, J; Su, L; Xu, Z; Yin, X; Yue, H; Zhang, S; Zhao, J1
Cho, YH; Kim, HN; Koh, JY; Lee, SH; Lee, SJ1
Anderson, BJ; Armstrong, NJ; Berryman, CE; Hennigar, SR; Karl, JP; Kelley, AM; McClung, HL; McClung, JP1

Reviews

1 review(s) available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and metallothionein

ArticleYear
[Role of intracellular zinc in programmed cell death].
    Pathologie-biologie, 2002, Volume: 50, Issue:3

    Topics: Animals; Apoptosis; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Catalysis; Cation Transport Proteins; Cell Nucleus; Cells, Cultured; Chelating Agents; Culture Media; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Ethylenediamines; Etoposide; Humans; Intracellular Fluid; Ion Transport; Membrane Proteins; Membrane Transport Proteins; Metalloproteins; Metallothionein; Tumor Necrosis Factor-alpha; Zinc

2002

Other Studies

25 other study(ies) available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and metallothionein

ArticleYear
Regulation of ZiRF1 and basal SP1 transcription factor MRE-binding activity by transition metals.
    FEBS letters, 1997, Oct-27, Volume: 416, Issue:3

    Topics: Animals; Base Sequence; Binding Sites; Cell Nucleus; Chelating Agents; DNA-Binding Proteins; Edetic Acid; Ethylenediamines; Gene Expression Regulation; Glutathione Transferase; L Cells; Metallothionein; Metals; Mice; Oligodeoxyribonucleotides; Phenanthrolines; Podophyllin; Podophyllotoxin; Promoter Regions, Genetic; Recombinant Fusion Proteins; Substrate Specificity; Transcription Factor MTF-1; Transcription Factors; Transfection

1997
Transient peaks in zinc and metallothionein levels during differentiation of 3T3L1 cells.
    Archives of biochemistry and biophysics, 1999, Apr-01, Volume: 364, Issue:1

    Topics: 3T3 Cells; Adipocytes; Animals; Apoptosis; Cell Differentiation; Cell Division; Cell Nucleus; Chelating Agents; Ethylenediamines; Flow Cytometry; Immunohistochemistry; Metallothionein; Mice; Subcellular Fractions; Zinc

1999
Impairment of cultured cell proliferation and metallothionein expression by metal chelator NNN'N'-tetrakis-(2-pyridylmethyl)ethylene diamine.
    Biological trace element research, 1999, Volume: 70, Issue:1

    Topics: Blotting, Northern; Cell Division; Cell Line, Transformed; Chelating Agents; Ethylenediamines; Gene Expression Regulation; Humans; Immunohistochemistry; Metallothionein; RNA, Messenger; Ultraviolet Rays; Zinc

1999
Metallothionein, nitric oxide and zinc homeostasis in vascular endothelial cells.
    The Journal of nutrition, 2000, Volume: 130, Issue:5S Suppl

    Topics: Animals; Antioxidants; Cells, Cultured; Chelating Agents; Cysteine; Drug Interactions; Endothelium, Vascular; Ethylenediamines; Fluorescent Dyes; Homeostasis; Metallothionein; Mice; Mice, Knockout; Nitric Oxide; Nitroso Compounds; Oxidation-Reduction; Pulmonary Artery; Quinolones; S-Nitrosothiols; Sheep; Tosyl Compounds; Zinc

2000
Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells.
    Oncogene, 2000, Nov-02, Volume: 19, Issue:46

    Topics: Animals; Cadmium; Cations, Divalent; Chelating Agents; Cobalt; DNA; Ethylenediamines; Fibroblasts; Humans; Metallothionein; Mice; Precipitin Tests; Protein Binding; Protein Conformation; Protein Folding; Protein Renaturation; Thermodynamics; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Zinc

2000
Effects of intracellular zinc depletion on metallothionein and ZIP2 transporter expression and apoptosis.
    Journal of leukocyte biology, 2001, Volume: 70, Issue:4

    Topics: Adult; Apoptosis; Carrier Proteins; Cation Transport Proteins; Cell Line; Cell Survival; Cells, Cultured; Chelating Agents; Cytoplasm; Ethylenediamines; Humans; Male; Metallothionein; Monocytes; RNA, Messenger; Transcription, Genetic; Zinc

2001
Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:2

    Topics: Animals; Cells, Cultured; Chelating Agents; Cysteine; Endothelium, Vascular; Ergothioneine; Ethylenediamines; Female; Fibroblasts; Fluorescent Dyes; Gene Expression; Homeostasis; Lung; Male; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Donors; Pulmonary Artery; Quinolones; S-Nitrosothiols; Sheep; Spectrometry, Fluorescence; Tosyl Compounds; Zinc

2002
Identification of genes responsive to intracellular zinc depletion in the human colon adenocarcinoma cell line HT-29.
    The Journal of nutrition, 2004, Volume: 134, Issue:1

    Topics: Adenocarcinoma; Apoptosis; Blotting, Northern; Cell Division; Chelating Agents; Colonic Neoplasms; DNA-Binding Proteins; Epithelial Cells; Ethylenediamines; Gene Expression; Gene Expression Regulation; Humans; Intestines; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Metallothionein; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured; Zinc

2004
ZINC-mediated gene expression offers protection against H2O2-induced cytotoxicity.
    Toxicology and applied pharmacology, 2005, Jun-15, Volume: 205, Issue:3

    Topics: Animals; Caspase 3; Caspases; Cell Death; Cell Survival; Cholinesterase Inhibitors; Culture Media; DNA Fragmentation; Ethylenediamines; Gene Expression; Gills; Glucosephosphate Dehydrogenase; Glutathione Transferase; Hydrogen Peroxide; L-Lactate Dehydrogenase; Metallothionein; Oncorhynchus mykiss; Oxidative Stress; RNA, Messenger; Zinc Sulfate

2005
Endothelial response to stress from exogenous Zn2+ resembles that of NO-mediated nitrosative stress, and is protected by MT-1 overexpression.
    American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:3

    Topics: Adenoviridae; Animals; Apoptosis; Cell Culture Techniques; Cell Survival; Chelating Agents; Endothelial Cells; Ethylenediamines; Fetus; Gene Expression; Homeostasis; Metallothionein; Microscopy, Fluorescence; Mitochondria; Nitric Oxide; Oxidative Stress; Pulmonary Artery; Reactive Nitrogen Species; Sheep; Zinc

2006
Alterations in zinc homeostasis underlie endothelial cell death induced by oxidative stress from acute exposure to hydrogen peroxide.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:1

    Topics: Animals; Apoptosis; Cells, Cultured; Chelating Agents; Endothelial Cells; Ethylenediamines; Homeostasis; Hydrogen Peroxide; Metallothionein; Oxidative Stress; Pulmonary Artery; Recombinant Proteins; Sheep; Signal Transduction; Zinc

2007
Apo-metallothionein emerging as a major player in the cellular activities of metallothionein.
    Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:9

    Topics: Animals; Dexamethasone; Ethylenediamines; Metallothionein; Mice; Mice, Nude; Mice, Transgenic; Myocardium; Neoplasm Transplantation; Zinc

2006
Cytotoxicity of nitric oxide is alleviated by zinc-mediated expression of antioxidant genes.
    Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:9

    Topics: Base Sequence; Cell Line, Tumor; DNA Primers; Ethylenediamines; Glucosephosphate Dehydrogenase; Glutathione Transferase; Humans; Metallothionein; Nitric Oxide; Nitric Oxide Donors; Nitrosation; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; Zinc

2006
Zinc binding ligands and cellular zinc trafficking: apo-metallothionein, glutathione, TPEN, proteomic zinc, and Zn-Sp1.
    Journal of inorganic biochemistry, 2008, Volume: 102, Issue:3

    Topics: Animals; Biological Transport; Carrier Proteins; Cell Line; Cell Line, Tumor; Cells, Cultured; Chromatography, Gel; Electrophoretic Mobility Shift Assay; Ethylenediamines; Glutathione; Humans; Metallothionein; Protein Binding; Rabbits; Sp1 Transcription Factor; Zinc

2008
Insights into Zn2+ homeostasis in neurons from experimental and modeling studies.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:3

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Chelating Agents; Clioquinol; Computer Simulation; Edetic Acid; Ethylenediamines; Homeostasis; Kinetics; Mass Spectrometry; Metallothionein; Models, Neurological; Neurons; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Fluorescence; Thiones; Zinc

2008
Nitric-oxide-mediated zinc release contributes to hypoxic regulation of pulmonary vascular tone.
    Circulation research, 2008, Jun-20, Volume: 102, Issue:12

    Topics: Animals; Aorta; Cell Size; Cells, Cultured; Chelating Agents; Endothelial Cells; Ethylenediamines; Hypoxia; In Vitro Techniques; Metallothionein; Mice; Mice, Transgenic; Microscopy, Fluorescence; Nitric Oxide; Nitrosation; Organ Specificity; Oxygen; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sheep; Vascular Resistance; Vasoconstriction; Zinc

2008
Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells.
    American journal of respiratory cell and molecular biology, 2009, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Bronchi; Cell Separation; Cells, Cultured; Chelating Agents; Chlorides; DNA-Binding Proteins; Epithelial Cells; Ethylamines; Flow Cytometry; Fluorescent Dyes; Humans; Metallothionein; Mice; Mice, Knockout; Nickel; Polycyclic Compounds; Pyridines; Pyrimidines; Reactive Oxygen Species; RNA, Messenger; Time Factors; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Transfection; Up-Regulation; Zinc Compounds

2009
Intracellular zinc stores protect the intestinal epithelium from Ochratoxin A toxicity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:8

    Topics: Caco-2 Cells; Cation Transport Proteins; Electric Impedance; Ethylamines; Humans; Intestinal Mucosa; Metallothionein; Ochratoxins; Pyridines; Zinc

2009
Zinc protects HepG2 cells against the oxidative damage and DNA damage induced by ochratoxin A.
    Toxicology and applied pharmacology, 2013, Apr-15, Volume: 268, Issue:2

    Topics: Catalase; Cytoprotection; DNA Damage; Ethylamines; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Metallothionein; Mycotoxins; Ochratoxins; Oxidation-Reduction; Oxidative Stress; Pyridines; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Zinc

2013
Effects of zinc supplementation and zinc chelation on in vitro β-cell function in INS-1E cells.
    BMC research notes, 2014, Feb-07, Volume: 7

    Topics: Animals; Apoptosis; Cation Transport Proteins; Cell Division; Cell Line; Chelating Agents; DNA, Complementary; Dose-Response Relationship, Drug; Ethylenediamines; Gene Expression Profiling; Gene Expression Regulation; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Metallothionein; Necrosis; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Zinc; Zinc Transporter 8

2014
Indomethacin preconditioning induces ischemic tolerance by modifying zinc availability in the brain.
    Neurobiology of disease, 2015, Volume: 81

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Carrier Proteins; Cell Death; Chelating Agents; Disease Models, Animal; Drug Administration Schedule; Ethylenediamines; HSP70 Heat-Shock Proteins; Hypoxia-Inducible Factor 1, alpha Subunit; Indomethacin; Infarction, Middle Cerebral Artery; Male; Metallothionein; Neurons; Rats; Rats, Sprague-Dawley; Time Factors; Zinc

2015
Acute changes in cellular zinc alters zinc uptake rates prior to zinc transporter gene expression in Jurkat cells.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2015, Volume: 28, Issue:6

    Topics: Cation Transport Proteins; Cations, Divalent; Chelating Agents; Dose-Response Relationship, Drug; Ethylamines; Gene Expression Regulation; Humans; Ion Transport; Jurkat Cells; Metallothionein; Protein Isoforms; Pyridines; Zinc; Zinc Sulfate

2015
HMBOX1 interacts with MT2A to regulate autophagy and apoptosis in vascular endothelial cells.
    Scientific reports, 2015, Oct-12, Volume: 5

    Topics: Apoptosis; Autophagy; Caspase 3; Ethylamines; Fibroblast Growth Factor 2; Gene Expression Regulation; HEK293 Cells; Homeodomain Proteins; Human Umbilical Vein Endothelial Cells; Humans; Immunoprecipitation; Metallothionein; Pyridines; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Two-Hybrid System Techniques; Zinc

2015
A role of metallothionein-3 in radiation-induced autophagy in glioma cells.
    Scientific reports, 2020, 02-06, Volume: 10, Issue:1

    Topics: Animals; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chelating Agents; Ethylenediamines; Gene Knockdown Techniques; Glioma; Humans; Lysosomes; Metallothionein; Metallothionein 3; Mice; Nerve Tissue Proteins; Photons; Radiation Tolerance; RNA, Small Interfering; Zinc

2020
Sensitivity and reliability of zinc transporter and metallothionein gene expression in peripheral blood mononuclear cells as indicators of zinc status: responses to
    The British journal of nutrition, 2021, 02-28, Volume: 125, Issue:4

    Topics: Adolescent; Adult; Carrier Proteins; Cells, Cultured; Ethylamines; Female; Gene Expression Regulation; Humans; Leukocytes, Mononuclear; Male; Metallothionein; Middle Aged; Protein Isoforms; Pyridines; RNA, Messenger; Young Adult; Zinc

2021