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n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and edetic acid

n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine has been researched along with edetic acid in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (28.00)18.2507
2000's9 (36.00)29.6817
2010's7 (28.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Abouelhassan, Y; Garrison, AT; Huigens, RW; Jin, S; Kallifidas, D; Kim, YS; Luesch, H; Tan, H1
Abouelhassan, Y; Chojnacki, M; Ding, Y; Dunman, PM; Fuse, MA; Huang, G; Huigens, RW; Jin, S; Kallifidas, D; Kundra, S; Lemos, JA; Liu, K; Luesch, H; Rohde, KH; Yang, H; Zhang, P1
Shi, J; Tong, R; Wang, T; Xiong, L; Xu, K; Zhao, L1
Aballay, A; Colombo, MI; Mayorga, LS; Sarrouf, MN; Stahl, PD1
McKain, N; Wallace, RJ1
Breed, WG; Jian, X; Lincoln, SF; Seamark, RF; Soon, LL; Sun, FZ; Ward, AD; Zalewski, PD1
Leone, A; Moltedo, O; Remondelli, P1
Dansithong, W; Paul, S; Sakabe, I; Shinozawa, T1
Balasubramanian, AS; Bhanumathy, CD1
Ahn, YS; Hsu, CY; Kim, CH; Kim, JH; Xu, J1
Armstrong, C; Lees, GJ; Leong, W1
Kamimura, I; Kariya, H; Kumaraswami, NS; Minagawa, N; Sakajo, S; Yoshimoto, A1
Hahn, BL; Lulloff, SJ; Sohnle, PG1
Choi, JS; Fujikado, T; Joo, CK; Kim, KA; Yoon, YJ1
Adrion, CB; Cai, F; Keller, JE1
Howes, JM; Laing, GD; Theakston, RD1
Bush, AI; Colvin, RA; Fontaine, CP; Holmes, WR; Kikuchi, K; Thomas, D; Volitakis, I1
Imai, S; Ishida, S; Matsuo, Y; Nishimura, Y; Okano, Y; Oyama, TB; Oyama, TM; Oyama, Y; Sakanashi, Y1
Connor, JA; Shuttleworth, CW; Vander Jagt, TA; Weiss, JH1
Kiedrowski, L1
Aiba, I; Carlson, AP; Sheline, CT; Shuttleworth, CW1
Briggs, DB; Giron, RM; Hart, MV; Hausrath, AC; Park, CK; Schnittker, K; Tsao, TS1
Che, JH; Cho, WS; Cho, Y; Jang, A; Jeong, J; Kang, BC; Kim, H; Kim, T; Ko, S; Lee, JK; Na, Y; Park, JS; Seok, SH; You, JR1
Furuta, T; Nagasawa, K; Nishida, K; Nishiura, T; Ohsato, Y; Segawa, S; Tani, M1
Catapano, MC; Karlíčková, J; Mercolini, L; Mladěnka, P; Tvrdý, V1

Reviews

1 review(s) available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and edetic acid

ArticleYear
Recent research and development of NDM-1 inhibitors.
    European journal of medicinal chemistry, 2021, Nov-05, Volume: 223

    Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Catalytic Domain; Drug Resistance, Bacterial; Molecular Docking Simulation; Picolinic Acids; Sulfonamides

2021

Other Studies

24 other study(ies) available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and edetic acid

ArticleYear
An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.
    Journal of medicinal chemistry, 2018, 05-10, Volume: 61, Issue:9

    Topics: Anti-Bacterial Agents; Biofilms; Cyclization; Halogenation; HeLa Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phenazines

2018
A Modular Synthetic Route Involving
    Journal of medicinal chemistry, 2021, 06-10, Volume: 64, Issue:11

    Topics: Aniline Compounds; Animals; Anti-Bacterial Agents; Biofilms; Cell Line; Cell Survival; Disease Models, Animal; Drug Design; Female; Halogenation; Humans; Iron; Iron Deficiencies; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Phenazines; Staphylococcal Infections; Structure-Activity Relationship; Wound Healing

2021
Zn2+ depletion blocks endosome fusion.
    The Biochemical journal, 1995, Dec-15, Volume: 312 ( Pt 3)

    Topics: Animals; Calcimycin; Calcium; Chelating Agents; Edetic Acid; Egtazic Acid; Endosomes; Ethylenediamines; Intracellular Membranes; Ionomycin; Membrane Fusion; Mice; Zinc

1995
Influence of 1,10-phenanthroline and its analogues, other chelators and transition metal ions on dipeptidase activity of the rumen bacterium, Prevotella ruminicola.
    The Journal of applied bacteriology, 1996, Volume: 81, Issue:1

    Topics: Animals; Chelating Agents; Dipeptidases; Edetic Acid; Egtazic Acid; Ethylenediamines; Ions; Metals; Phenanthrolines; Prevotella; Rumen; Sheep; Structure-Activity Relationship

1996
Changes in distribution of labile zinc in mouse spermatozoa during maturation in the epididymis assessed by the fluorophore Zinquin.
    Reproduction, fertility, and development, 1996, Volume: 8, Issue:7

    Topics: Animals; Chelating Agents; Chromatin; Edetic Acid; Epididymis; Ethylenediamines; Female; Fluorescent Dyes; Male; Mice; Microscopy, Fluorescence; Octoxynol; Quinolones; Rats; Spermatozoa; Tosyl Compounds; Uterus; Zinc

1996
Regulation of ZiRF1 and basal SP1 transcription factor MRE-binding activity by transition metals.
    FEBS letters, 1997, Oct-27, Volume: 416, Issue:3

    Topics: Animals; Base Sequence; Binding Sites; Cell Nucleus; Chelating Agents; DNA-Binding Proteins; Edetic Acid; Ethylenediamines; Gene Expression Regulation; Glutathione Transferase; L Cells; Metallothionein; Metals; Mice; Oligodeoxyribonucleotides; Phenanthrolines; Podophyllin; Podophyllotoxin; Promoter Regions, Genetic; Recombinant Fusion Proteins; Substrate Specificity; Transcription Factor MTF-1; Transcription Factors; Transfection

1997
Induction of apoptosis in Neuro-2A cells by Zn2+ chelating.
    Cell structure and function, 1998, Volume: 23, Issue:2

    Topics: Animals; Apoptosis; Cell Division; Cell Nucleus; Chelating Agents; Copper; DNA Fragmentation; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Ethylenediamines; Iron; Manganese; Mice; Neuroblastoma; Tumor Cells, Cultured; Zinc

1998
Selective inactivation of butyrylcholinesterase with metal chelators suggests there is more than one metal binding site.
    The international journal of biochemistry & cell biology, 1998, Volume: 30, Issue:6

    Topics: Binding Sites; Butyrylcholinesterase; Catalysis; Chelating Agents; Cholinesterase Inhibitors; Chromatography, Gel; Cysteine; Dextrans; Edetic Acid; Ethylenediamines; Histidine; Humans; Metals; Phenanthrolines; Spectrophotometry, Atomic; Time Factors; Zinc

1998
Pyrrolidine dithiocarbamate induces bovine cerebral endothelial cell death by increasing the intracellular zinc level.
    Journal of neurochemistry, 1999, Volume: 72, Issue:4

    Topics: Animals; Antioxidants; Calcium; Cattle; Cell Death; Cerebral Cortex; Chelating Agents; Copper; Copper Sulfate; Edetic Acid; Endothelium; Ethylenediamines; L-Lactate Dehydrogenase; Phenanthrolines; Pyrrolidines; Thiocarbamates; Zinc

1999
Comparative effects of metal chelating agents on the neuronal cytotoxicity induced by copper (Cu+2), iron (Fe+3) and zinc in the hippocampus.
    Brain research, 2001, Feb-16, Volume: 892, Issue:1

    Topics: Animals; Cell Survival; Chelating Agents; Chlorides; Copper Sulfate; Cytotoxins; Deferoxamine; Edetic Acid; Ethylenediamines; Ferric Compounds; Hippocampus; Male; Neurons; Phenanthrolines; Rats; Rats, Wistar; Zinc

2001
Zinc is involved in the expression of a nuclear-encoded alternative oxidase gene in the yeast Hansenula anomala.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:12

    Topics: Cell Nucleus; Chelating Agents; Edetic Acid; Ethylenediamines; Gene Expression Regulation, Fungal; Oxidoreductases; Pichia; Pyridines; RNA, Messenger; Thiones; Zinc

2002
Fungal susceptibility to zinc deprivation.
    The Journal of laboratory and clinical medicine, 2004, Volume: 144, Issue:4

    Topics: Candida albicans; Chelating Agents; Edetic Acid; Ethylenediamines; Fungi; Humans; In Vitro Techniques; Leukocyte L1 Antigen Complex; Metals; Pentetic Acid; Zinc

2004
Inhibition of cyclooxygenase-2 expression by zinc-chelator in retinal ischemia.
    Vision research, 2006, Volume: 46, Issue:17

    Topics: Animals; Chelating Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Edetic Acid; Ethylenediamines; Ischemia; Male; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Retinal Ganglion Cells; Retinal Vessels; Zinc

2006
Comparison of extracellular and intracellular potency of botulinum neurotoxins.
    Infection and immunity, 2006, Volume: 74, Issue:10

    Topics: Animals; Biological Assay; Botulinum Toxins; Botulinum Toxins, Type A; Cells, Cultured; Chelating Agents; Edetic Acid; Ethylenediamines; Mice; Mice, Inbred C57BL; Neurons; Neurotoxins; Peptide Hydrolases; Zinc

2006
Neutralization of the haemorrhagic activities of viperine snake venoms and venom metalloproteinases using synthetic peptide inhibitors and chelators.
    Toxicon : official journal of the International Society on Toxinology, 2007, Volume: 49, Issue:5

    Topics: Animals; Biphenyl Compounds; Chelating Agents; Chromatography, Gel; Chromatography, Liquid; Edetic Acid; Egtazic Acid; Ethylenediamines; Evaluation Studies as Topic; Hemorrhage; Hydroxamic Acids; Metalloproteases; Mice; Molecular Structure; Organic Chemicals; Phenylbutyrates; Protein Kinase Inhibitors; Pyrazines; Snake Bites; Statistics, Nonparametric; Sulfonamides; Viper Venoms

2007
Insights into Zn2+ homeostasis in neurons from experimental and modeling studies.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:3

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Chelating Agents; Clioquinol; Computer Simulation; Edetic Acid; Ethylenediamines; Homeostasis; Kinetics; Mass Spectrometry; Metallothionein; Models, Neurological; Neurons; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Fluorescence; Thiones; Zinc

2008
Zn(2+), derived from cell preparation, partly attenuates Ca(2+)-dependent cell death induced by A23187, calcium ionophore, in rat thymocytes.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:2

    Topics: Animals; Apoptosis; Calcimycin; Calcium Compounds; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Edetic Acid; Ethylenediamines; Ionophores; Rats; Thymus Gland; Zinc Compounds

2009
Intracellular Zn2+ increases contribute to the progression of excitotoxic Ca2+ increases in apical dendrites of CA1 pyramidal neurons.
    Neuroscience, 2009, Mar-03, Volume: 159, Issue:1

    Topics: Animals; Calcium; Chelating Agents; Dendrites; Edetic Acid; Ethylenediamines; Excitatory Amino Acid Agonists; Extracellular Fluid; Hippocampus; In Vitro Techniques; Male; Mice; N-Methylaspartate; Polycyclic Compounds; Pyramidal Cells; Time Factors; Zinc

2009
Cytosolic zinc release and clearance in hippocampal neurons exposed to glutamate--the role of pH and sodium.
    Journal of neurochemistry, 2011, Volume: 117, Issue:2

    Topics: Animals; Calcium; Cells, Cultured; Chelating Agents; Cytosol; Dose-Response Relationship, Drug; Edetic Acid; Embryo, Mammalian; Ethylenediamines; Excitatory Amino Acid Agonists; Fura-2; Glutamic Acid; Glycine; Hippocampus; Hydrogen-Ion Concentration; Mice; N-Methylaspartate; Neurons; Polycyclic Compounds; Sodium; Statistics, Nonparametric; Zinc

2011
Synaptic release and extracellular actions of Zn2+ limit propagation of spreading depression and related events in vitro and in vivo.
    Journal of neurophysiology, 2012, Volume: 107, Issue:3

    Topics: Animals; CA1 Region, Hippocampal; Carrier Proteins; Cation Transport Proteins; Chelating Agents; Cortical Spreading Depression; Edetic Acid; Ethylenediamines; Female; Hippocampus; Male; Membrane Proteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroglia; Neurons; Parietal Lobe; Potassium Chloride; Synapses; Zinc

2012
Zinc enhances adiponectin oligomerization to octadecamers but decreases the rate of disulfide bond formation.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2012, Volume: 25, Issue:2

    Topics: Adiponectin; Animals; Disulfides; Dithiothreitol; Edetic Acid; Ethylenediamines; Female; Hydrogen-Ion Concentration; Pentetic Acid; Protein Multimerization; Rats; Rats, Zucker; Zinc

2012
Rat pancreatitis produced by 13-week administration of zinc oxide nanoparticles: biopersistence of nanoparticles and possible solutions.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:10

    Topics: Administration, Oral; Animals; Carcinogens; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Ethylenediamines; Female; Humans; Male; Nanoparticles; No-Observed-Adverse-Effect Level; Organ Size; Pancreatitis; Rats; Rats, Sprague-Dawley; Toxicity Tests, Subchronic; Zinc Oxide

2013
Zinc is released by cultured astrocytes as a gliotransmitter under hypoosmotic stress-loaded conditions and regulates microglial activity.
    Life sciences, 2014, Jan-17, Volume: 94, Issue:2

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Cation Transport Proteins; Cells, Cultured; Edetic Acid; Ethylenediamines; Mice; Microglia; Neurotransmitter Agents; Osmotic Pressure; Real-Time Polymerase Chain Reaction; Zinc

2014
A simple, cheap but reliable method for evaluation of zinc chelating properties.
    Bioorganic chemistry, 2018, Volume: 77

    Topics: Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Ethylenediamines; Molecular Structure; Structure-Activity Relationship; Zinc

2018