Page last updated: 2024-09-03

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and scopolamine hydrobromide

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride has been researched along with scopolamine hydrobromide in 5 studies

Compound Research Comparison

Studies
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Trials
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Recent Studies (post-2010)
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Studies
(scopolamine hydrobromide)
Trials
(scopolamine hydrobromide)
Recent Studies (post-2010) (scopolamine hydrobromide)
980297,5485631,401

Protein Interaction Comparison

ProteinTaxonomyn,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride (IC50)scopolamine hydrobromide (IC50)
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.003
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.006
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.006
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.006
Cytochrome P450 3A4Homo sapiens (human)0.0006
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.006
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.006
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0026

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maurice, T; Privat, A; Urani, A1
Altar, CA; Kikuchi, T; Miwa, T; Nakai, M; Oshiro, Y; Tottori, K; Uwahodo, Y; Yamada, S1
Hiramatsu, M; Hoshino, T; Kanematsu, K1
Hiramatsu, M; Hoshino, T1
Araki, H; Hato-Yamada, N; Su, J; Yoshimura, H1

Other Studies

5 other study(ies) available for n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and scopolamine hydrobromide

ArticleYear
The modulation by neurosteroids of the scopolamine-induced learning impairment in mice involves an interaction with sigma1 (sigma1) receptors.
    Brain research, 1998, Jul-13, Volume: 799, Issue:1

    Topics: Animals; Anisoles; Dehydroepiandrosterone Sulfate; Learning Disabilities; Male; Maze Learning; Mice; Muscarinic Antagonists; Pregnenolone; Progesterone; Propylamines; Receptors, sigma; Scopolamine; Swimming

1998
Attenuation of scopolamine-induced and age-associated memory impairments by the sigma and 5-hydroxytryptamine(1A) receptor agonist OPC-14523 (1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2[1H]-quinolinone monomethanesulfonate).
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:1

    Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Anisoles; Avoidance Learning; Brain Chemistry; Cholinergic Agents; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Male; Maze Learning; Memory Disorders; Microdialysis; Muscarinic Antagonists; Piperazines; Propylamines; Quinolones; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, sigma; Scopolamine; Serotonin Receptor Agonists

2002
Pharmacological characterization of the ameliorating effect on short-term memory impairment and antinociceptive effect of KT-90 in mice.
    Behavioural brain research, 2005, May-28, Volume: 160, Issue:2

    Topics: Animals; Anisoles; Antipsychotic Agents; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Morphine Derivatives; Narcotic Antagonists; Pain; Pain Measurement; Propylamines; Receptors, Opioid; Scopolamine; Statistics, Nonparametric

2005
Improvement of memory impairment by (+)- and (-)-pentazocine via sigma, but not kappa opioid receptors.
    Brain research, 2005, Sep-28, Volume: 1057, Issue:1-2

    Topics: Acetic Acid; Analgesics, Opioid; Analysis of Variance; Animals; Anisoles; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Isomerism; Male; Maze Learning; Memory Disorders; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Pentazocine; Propylamines; Receptors, Opioid, kappa; Receptors, sigma; Scopolamine

2005
Test-retest paradigm of the forced swimming test in female mice is not valid for predicting antidepressant-like activity: participation of acetylcholine and sigma-1 receptors.
    Journal of pharmacological sciences, 2013, Volume: 123, Issue:3

    Topics: Acetylcholine; Animals; Anisoles; Antidepressive Agents; Cholinergic Antagonists; Female; Forecasting; Imipramine; Mice; Mice, Inbred ICR; Motor Activity; Paroxetine; Propylamines; Receptors, sigma; Scopolamine; Stress, Psychological; Swimming

2013