Page last updated: 2024-09-03

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and rimcazole

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride has been researched along with rimcazole in 4 studies

Compound Research Comparison

Studies
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Trials
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Recent Studies (post-2010)
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Studies
(rimcazole)
Trials
(rimcazole)
Recent Studies (post-2010) (rimcazole)
502103213
98029103213

Protein Interaction Comparison

ProteinTaxonomyn,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride (IC50)rimcazole (IC50)
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.14
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)1.0235
Scavenger receptor class B member 1Homo sapiens (human)1.2
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.9196
Sigma non-opioid intracellular receptor 1Rattus norvegicus (Norway rat)1.4152

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, J; Katz, JL; Kopajtic, T; Newman, AH1
Collina, S; Cortesi, M; Curti, D; Laurini, E; Marra, A; Pace, V; Paolillo, M; Pricl, S; Rossi, D; Rui, M; Schepmann, D; Schinelli, S; Tesei, A; Urban, E; Wűnsch, B; Zamagni, A1
Araki, H; Ogawa, S; Okuyama, S; Otomo, S; Tsuchida, K1
Cao, J; Hiranita, T; Katz, JL; Kohut, SJ; Kopajtic, T; Newman, AH; Soto, PL; Tanda, G1

Other Studies

4 other study(ies) available for n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and rimcazole

ArticleYear
Dual DAT/sigma1 receptor ligands based on 3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-1-phenylpropan-1-ol.
    Bioorganic & medicinal chemistry letters, 2008, Oct-01, Volume: 18, Issue:19

    Topics: Animals; Carbazoles; Cocaine; Combinatorial Chemistry Techniques; Dopamine Plasma Membrane Transport Proteins; Molecular Structure; Piperazines; Protein Binding; Rats; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship

2008
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Molecular Structure; PC12 Cells; Piperidines; Rats; Receptors, sigma

2016
The sigma-selective ligand NE-100 attenuates the effect of phencyclidine in a rat diving model.
    General pharmacology, 1995, Volume: 26, Issue:1

    Topics: Animals; Anisoles; Carbazoles; Diving; Male; Motor Activity; Phencyclidine; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma

1995
Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: Animals; Anisoles; Antipsychotic Agents; Carbazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Molecular Targeted Therapy; Oxalates; Piperidines; Propylamines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Reinforcement, Psychology; Self Administration

2011