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n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and pentazocine

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride has been researched along with pentazocine in 17 studies

Compound Research Comparison

Studies
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Trials
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Recent Studies (post-2010)
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Studies
(pentazocine)
Trials
(pentazocine)
Recent Studies (post-2010) (pentazocine)
980292,262353138

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (58.82)18.2507
2000's4 (23.53)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chaki, S; Muramatsu, M; Nakazato, A; Okuyama, S; Yae, T1
Chaki, S; Muramatsu, M; Otomo, S; Tanaka, M1
Bowen, WD; de Costa, BR; Monnet, FP1
Chaki, S; Muramatsu, M; Nakazato, A; Ogawa, S; Okuyama, S; Tanaka, M; Tomisawa, K1
Kobayashi, T; Matsuno, K; Mita, S; Tanaka, MK1
Matsuno, K; Mita, S; Nakazawa, M1
Kameyama, T; Maeda, H; Matsuno, K; Nanya, Y; Ukai, M1
Miura, R; Nakazato, A; Nukada, T; Okuyama, S; Shinohara, K; Watanabe, M; Yamamoto, H; Yamamoto, T1
Cazin, L; Foll, FL; Monnet, FP; Roman, F; Soriani, O; Vaudry, H1
Bucolo, C; Cacciaguerra, S; Campana, G; Di Toro, R; Spampinato, S1
Horikomi, K; Karasawa, J; Nukada, T; Okuyama, S; Sagi, N; Sora, I; Takahashi, S; Yamamoto, H; Yamamoto, T1
Abate, C; Berardi, F; Colabufo, NA; Contino, M; Niso, M; Perrone, R; Tortorella, V1
Hiramatsu, M; Hoshino, T1
Baeyens, JM; Cobos, EJ; Del Pozo, E; Lucena, G1
Isotani, K; Mori, T; Narita, M; Nomura, M; Suzuki, T; Torigoe, K; Tsukiyama, Y; Yoshizawa, K1
Bhuiyan, MS; Fukunaga, K; Tagashira, H1
Betz, RM; Dror, RO; Kruse, AC; Schmidt, HR1

Other Studies

17 other study(ies) available for n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and pentazocine

ArticleYear
Autoradiographic characterization of binding sites for [3H]NE-100 in guinea pig brain.
    Life sciences, 1995, Volume: 57, Issue:21

    Topics: Animals; Anisoles; Autoradiography; Binding Sites; Brain; Guinea Pigs; Ligands; Male; Pentazocine; Propylamines; Receptors, sigma; Tritium

1995
NE-100, a novel potent sigma ligand, preferentially binds to sigma 1 binding sites in guinea pig brain.
    European journal of pharmacology, 1994, Jan-04, Volume: 251, Issue:1

    Topics: Animals; Anisoles; Binding, Competitive; Brain; Guanidines; Guinea Pigs; In Vitro Techniques; Ligands; Pentazocine; Propylamines; Receptors, sigma

1994
Differentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slices.
    British journal of pharmacology, 1996, Volume: 119, Issue:1

    Topics: Animals; Anisoles; Anticonvulsants; Antipsychotic Agents; Cyclohexylamines; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Ligands; Male; N-Methylaspartate; Narcotics; Norepinephrine; Pentazocine; Propylamines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Tritium

1996
Solubilization and characterization of binding sites for [3H]NE-100, a novel and potent sigma 1 ligand, from guinea pig brain.
    Life sciences, 1996, Volume: 59, Issue:16

    Topics: Animals; Anisoles; Binding, Competitive; Brain; Dextromethorphan; Guinea Pigs; Ligands; Male; Pentazocine; Phenytoin; Propylamines; Radioligand Assay; Receptors, sigma; Tritium

1996
Sigma 1 receptor subtype is involved in the relief of behavioral despair in the mouse forced swimming test.
    European journal of pharmacology, 1996, Oct-03, Volume: 312, Issue:3

    Topics: Animals; Anisoles; Cinnamates; Cyclopropanes; Guanidines; Male; Mice; Mice, Inbred Strains; Motor Activity; Pentazocine; Piperazines; Propylamines; Receptors, sigma; Stress, Physiological

1996
Activation of sigma1 receptor subtype leads to neuroprotection in the rat primary neuronal cultures.
    Neurochemistry international, 1998, Volume: 32, Issue:4

    Topics: Animals; Anisoles; Cells, Cultured; Ligands; Neurons; Nootropic Agents; Pentazocine; Piperazines; Propylamines; Rats; Rats, Wistar; Receptors, sigma

1998
Beneficial effects of acute and repeated administrations of sigma receptor agonists on behavioral despair in mice exposed to tail suspension.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 61, Issue:3

    Topics: Animals; Anisoles; Antidepressive Agents; Body Weight; Desipramine; Drug Interactions; Fluoxetine; Hindlimb Suspension; Male; Mice; Motor Activity; Narcotics; Nootropic Agents; Pentazocine; Piperazines; Propylamines; Receptors, sigma

1998
Amino acid residues in the transmembrane domain of the type 1 sigma receptor critical for ligand binding.
    FEBS letters, 1999, Feb-19, Volume: 445, Issue:1

    Topics: Amino Acids; Animals; Anisoles; Binding Sites; Cell Membrane; Gene Expression; Guinea Pigs; Ligands; Oocytes; Pentazocine; Propylamines; Rabbits; Receptors, sigma; Sigma-1 Receptor; Xenopus

1999
A-Current down-modulated by sigma receptor in frog pituitary melanotrope cells through a G protein-dependent pathway.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:1

    Topics: Animals; Anisoles; Cells, Cultured; Cinnamates; Cyclopropanes; Down-Regulation; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Melanocyte-Stimulating Hormones; Membrane Potentials; Patch-Clamp Techniques; Pentazocine; Pituitary Gland; Potassium Channels; Propylamines; Rana ridibunda; Receptors, sigma; Signal Transduction

1999
Sigma1 recognition sites in rabbit iris-ciliary body: topical sigma1-site agonists lower intraocular pressure.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Animals; Anisoles; Antipsychotic Agents; Binding, Competitive; Cell Membrane; Ciliary Body; Functional Laterality; Guanidines; Intraocular Pressure; Iris; Kinetics; Lens, Crystalline; Male; Pentazocine; Phenazocine; Propylamines; Rabbits; Receptors, sigma; Retina; Tritium

1999
Multiple pathways of sigma(1) receptor ligand uptakes into primary cultured neuronal cells.
    European journal of pharmacology, 2001, Aug-03, Volume: 425, Issue:1

    Topics: Animals; Anisoles; Arsenicals; Biological Transport; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Haloperidol; Hydroquinones; Kinetics; Ligands; Neurons; Ouabain; Pentazocine; Piperazines; Propylamines; Pyrrolidines; Rats; Receptors, sigma; Sigma-1 Receptor; Sodium; Sulfonamides; Tartrates; Thapsigargin; Time Factors; Tritium

2001
Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Animals; Anisoles; Antineoplastic Agents; Binding, Competitive; Brain; Cell Line, Tumor; Guanidines; Guinea Pigs; Haloperidol; Humans; In Vitro Techniques; Ligands; Liver; Membranes; Pentazocine; Piperazines; Propylamines; Pyridines; Radioligand Assay; Rats; Receptors, sigma; Sigma-1 Receptor

2004
Improvement of memory impairment by (+)- and (-)-pentazocine via sigma, but not kappa opioid receptors.
    Brain research, 2005, Sep-28, Volume: 1057, Issue:1-2

    Topics: Acetic Acid; Analgesics, Opioid; Analysis of Variance; Animals; Anisoles; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Isomerism; Male; Maze Learning; Memory Disorders; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Pentazocine; Propylamines; Receptors, Opioid, kappa; Receptors, sigma; Scopolamine

2005
Differences in the allosteric modulation by phenytoin of the binding properties of the sigma1 ligands [3H](+)-pentazocine and [3H]NE-100.
    Synapse (New York, N.Y.), 2006, Mar-01, Volume: 59, Issue:3

    Topics: Analgesics, Opioid; Animals; Anisoles; Anticonvulsants; Brain; Data Interpretation, Statistical; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Membranes; Pentazocine; Phenytoin; Propylamines; Radioligand Assay; Receptors, Opioid, delta

2006
Sigma-1 receptor function is critical for both the discriminative stimulus and aversive effects of the kappa-opioid receptor agonist U-50488H.
    Addiction biology, 2012, Volume: 17, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anisoles; Avoidance Learning; Conditioning, Psychological; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Narcotic Antagonists; Pentazocine; Phenazocine; Phencyclidine; Propylamines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Receptors, sigma; Sigma-1 Receptor

2012
Diverse regulation of IP3 and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes.
    American journal of physiology. Heart and circulatory physiology, 2013, Oct-15, Volume: 305, Issue:8

    Topics: Adenosine Triphosphate; Angiotensin II; Animals; Anisoles; Calcium; Cardiomegaly; Cells, Cultured; Female; Heart; Hypertrophy, Left Ventricular; Inositol 1,4,5-Trisphosphate Receptors; Mitochondria; Myocardial Contraction; Myocytes, Cardiac; Narcotic Antagonists; Narcotics; Ovariectomy; Pentazocine; Propylamines; Rats; Rats, Wistar; Receptors, sigma; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sigma-1 Receptor; Vasoconstrictor Agents

2013
Structural basis for σ
    Nature structural & molecular biology, 2018, Volume: 25, Issue:10

    Topics: Anisoles; Crystallography, X-Ray; Haloperidol; Humans; Ligands; Models, Molecular; Molecular Docking Simulation; Pentazocine; Propylamines; Protein Domains; Receptors, sigma

2018