n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and metoprolol

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride has been researched along with metoprolol in 2 studies

Compound Research Comparison

Studies (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)	Trials (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)	Recent Studies (post-2010) (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)	Studies (metoprolol)	Trials (metoprolol)	Recent Studies (post-2010) (metoprolol)
98	0	29	5,821	1,743	1,304

Protein Interaction Comparison

Protein	Taxonomy	metoprolol (IC50)
Beta-2 adrenergic receptor	Homo sapiens (human)	2.573
Beta-1 adrenergic receptor	Homo sapiens (human)	0.176
Cytochrome P450 2C9	Homo sapiens (human)	4.87
Cytochrome P450 2J2	Homo sapiens (human)	4.87

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Itoga, H; Kohno, Y; Nagata, K; Yamamoto, T; Yamazoe, Y	1
Kohno, Y; Nagata, K; Suzuki, A; Yamamoto, T; Yamazoe, Y	1

Other Studies

2 other study(ies) available for n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and metoprolol

Article	Year
Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: comparison among well-stirred, parallel-tube, distributed and dispersion models. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:6 Topics: Administration, Oral; Animals; Anisoles; Aryl Hydrocarbon Hydroxylases; Clarithromycin; Cytochrome P-450 Enzyme System; Dogs; Humans; Male; Metabolic Clearance Rate; Metoprolol; Models, Biological; Piroxicam; Predictive Value of Tests; Propylamines; Rats; Rats, Wistar; Recombinant Proteins	2005
Prediction of drug-drug interactions for AUCoral of high clearance drug from in vitro data: utilization of a microtiter plate assay and a dispersion model. Current drug metabolism, 2006, Volume: 7, Issue:2 Topics: Administration, Oral; Adrenergic beta-Antagonists; Algorithms; Animals; Anisoles; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Area Under Curve; Baculoviridae; Desipramine; Drug Interactions; Humans; In Vitro Techniques; Insecta; Metoprolol; Microsomes; Microsomes, Liver; Models, Statistical; Propafenone; Propylamines; Thioridazine	2006

Article

Year

Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: comparison among well-stirred, parallel-tube, distributed and dispersion models.

Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:6

Topics: Administration, Oral; Animals; Anisoles; Aryl Hydrocarbon Hydroxylases; Clarithromycin; Cytochrome P-450 Enzyme System; Dogs; Humans; Male; Metabolic Clearance Rate; Metoprolol; Models, Biological; Piroxicam; Predictive Value of Tests; Propylamines; Rats; Rats, Wistar; Recombinant Proteins

2005

Prediction of drug-drug interactions for AUCoral of high clearance drug from in vitro data: utilization of a microtiter plate assay and a dispersion model.

Current drug metabolism, 2006, Volume: 7, Issue:2

Topics: Administration, Oral; Adrenergic beta-Antagonists; Algorithms; Animals; Anisoles; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Area Under Curve; Baculoviridae; Desipramine; Drug Interactions; Humans; In Vitro Techniques; Insecta; Metoprolol; Microsomes; Microsomes, Liver; Models, Statistical; Propafenone; Propylamines; Thioridazine

2006