n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride has been researched along with haloperidol in 14 studies
| Studies (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride) | Trials (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride) | Recent Studies (post-2010) (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride) | Studies (haloperidol) | Trials (haloperidol) | Recent Studies (post-2010) (haloperidol) |
|---|---|---|---|---|---|
| 5 | 0 | 2 | 20,330 | 1,753 | 3,294 |
| 98 | 0 | 29 | 20,330 | 1,753 | 3,294 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chaki, S; Hatayama, K; Kawashima, Y; Nakazato, A; Ohta, K; Okuyama, S; Sekiguchi, Y | 1 |
| Banister, SD; Chua, SW; Jorgensen, WT; Kassiou, M; Moussa, IA | 1 |
| Shibata, S; Watanabe, S; Yamamoto, Y | 1 |
| Bergeron, R; de Montigny, C; Debonnel, G | 1 |
| Hashimoto, K; Iyo, M; Minabe, Y; Narita, N; Yamazaki, K | 1 |
| Bowen, WD; de Costa, BR; Monnet, FP | 1 |
| Hatano, K; Ishii, S; Ishiwata, K; Ito, K; Nabeshima, T; Noguchi, J; Senda, M | 1 |
| Horikomi, K; Karasawa, J; Nukada, T; Okuyama, S; Sagi, N; Sora, I; Takahashi, S; Yamamoto, H; Yamamoto, T | 1 |
| Abate, C; Berardi, F; Colabufo, NA; Contino, M; Niso, M; Perrone, R; Tortorella, V | 1 |
| Baeyens, JM; Cobos, EJ; Del Pozo, E | 1 |
| Chen, L; Dai, XN; Sokabe, M | 1 |
| Bermack, JE; Debonnel, G | 1 |
| Bastianetto, S; Danik, M; Mennicken, F; Quirion, R; Williams, S | 1 |
| Betz, RM; Dror, RO; Kruse, AC; Schmidt, HR | 1 |
14 other study(ies) available for n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and haloperidol
| Article | Year |
|---|---|
Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine sigma ligands as potential antipsychotic drugs.
Topics: Animals; Anisoles; Antipsychotic Agents; Brain; Drug Design; Drug Evaluation, Preclinical; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Propylamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, sigma; Stereotyped Behavior; Structure-Activity Relationship | 1999 |
Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (σ) receptor ligands modulates off-target activity and subtype selectivity.
Topics: Alkanes; Aza Compounds; Cyclization; Dodecanol; Haloperidol; Ligands; Molecular Structure; Receptors, Dopamine; Receptors, sigma; Substrate Specificity | 2011 |
A role of sigma receptors on hypoxia/hypoglycemia-induced decrease in CA1 presynaptic fiber spikes in rat hippocampal slices.
Topics: Action Potentials; Animals; Anisoles; Guanidines; Haloperidol; Hippocampus; Hypoglycemia; Hypoxia, Brain; In Vitro Techniques; Male; Nerve Fibers; Presynaptic Terminals; Propylamines; Rats; Rats, Wistar; Receptors, sigma | 1995 |
Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors.
Topics: Animals; Anisoles; Dehydroepiandrosterone; Drug Synergism; Female; Guanidines; Haloperidol; Hippocampus; Iontophoresis; Ligands; Male; N-Methylaspartate; Pertussis Toxin; Pregnenolone; Progesterone; Propylamines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spiperone; Virulence Factors, Bordetella | 1996 |
Lack of neuroprotective effect of sigma receptor ligands in the neurotoxicity of p-chloroamphetamine in rat brain.
Topics: Animals; Anisoles; Antitussive Agents; Cerebral Cortex; Dextromethorphan; Haloperidol; Hydroxyindoleacetic Acid; Ligands; Male; p-Chloroamphetamine; Propylamines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin; Serotonin Agents | 1995 |
Differentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slices.
Topics: Animals; Anisoles; Anticonvulsants; Antipsychotic Agents; Cyclohexylamines; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Ligands; Male; N-Methylaspartate; Narcotics; Norepinephrine; Pentazocine; Propylamines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Tritium | 1996 |
Synthesis and preliminary evaluation of [11C]NE-100 labeled in two different positions as a PET sigma receptor ligand.
Topics: Animals; Anisoles; Autoradiography; Biological Transport; Brain; Carbon Radioisotopes; Haloperidol; Indicators and Reagents; Isotope Labeling; Ligands; Male; Mice; Propylamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, sigma; Tissue Distribution; Tomography, Emission-Computed | 1998 |
Multiple pathways of sigma(1) receptor ligand uptakes into primary cultured neuronal cells.
Topics: Animals; Anisoles; Arsenicals; Biological Transport; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Haloperidol; Hydroquinones; Kinetics; Ligands; Neurons; Ouabain; Pentazocine; Piperazines; Propylamines; Pyrrolidines; Rats; Receptors, sigma; Sigma-1 Receptor; Sodium; Sulfonamides; Tartrates; Thapsigargin; Time Factors; Tritium | 2001 |
Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines.
Topics: Animals; Anisoles; Antineoplastic Agents; Binding, Competitive; Brain; Cell Line, Tumor; Guanidines; Guinea Pigs; Haloperidol; Humans; In Vitro Techniques; Ligands; Liver; Membranes; Pentazocine; Piperazines; Propylamines; Pyridines; Radioligand Assay; Rats; Receptors, sigma; Sigma-1 Receptor | 2004 |
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
Topics: Allosteric Regulation; Animals; Anisoles; Anticonvulsants; Binding, Competitive; Brain; Dextromethorphan; Drug Interactions; Ethylenediamines; Guinea Pigs; Haloperidol; Ligands; Male; Morpholines; Neurons; Phenazocine; Phenytoin; Piperazines; Piperidines; Progesterone; Propylamines; Receptors, sigma; Synaptic Transmission | 2005 |
Chronic administration of dehydroepiandrosterone sulfate (DHEAS) primes for facilitated induction of long-term potentiation via sigma 1 (sigma1) receptor: optical imaging study in rat hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anisoles; Bicuculline; Dehydroepiandrosterone Sulfate; Diagnostic Imaging; Dose-Response Relationship, Radiation; Drug Combinations; Drug Interactions; Electric Stimulation; Endoplasmic Reticulum; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Haloperidol; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Membrane Proteins; Propylamines; Rats; Rats, Wistar; Tetrodotoxin | 2006 |
Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Anisoles; Antidepressive Agents; Autoreceptors; Brain; Haloperidol; Hypothalamus; Iontophoresis; Male; Piperazines; Presynaptic Terminals; Propylamines; Pyramidal Cells; Pyridines; Quinolones; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, sigma; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses | 2007 |
Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation.
Topics: Animals; Anisoles; Antipsychotic Agents; Benzazepines; Butaclamol; Caspase Inhibitors; Cell Death; Cells, Cultured; Chlorpromazine; Clozapine; Domperidone; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ginkgo biloba; Haloperidol; Hippocampus; Indans; Isoxazoles; Neurons; Neuroprotective Agents; Peptides; Piperidines; Plant Extracts; Propylamines; Raclopride; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Remoxipride; Risperidone; Sulpiride | 2006 |
Structural basis for σ
Topics: Anisoles; Crystallography, X-Ray; Haloperidol; Humans; Ligands; Models, Molecular; Molecular Docking Simulation; Pentazocine; Propylamines; Protein Domains; Receptors, sigma | 2018 |